Diagnostic and Interventional Imaging最新文献

{"title":"Photon-counting CT-derived extracellular volume in acute myocarditis: Comparison with cardiac MRI","authors":"Christos Gkizas ,&nbsp;Benjamin Longere ,&nbsp;Olga Sliwicka ,&nbsp;Aimee Rodriguez Musso ,&nbsp;Gilles Lemesle ,&nbsp;Cedric Croisille ,&nbsp;Mehdi Haidar ,&nbsp;Francois Pontana","doi":"10.1016/j.diii.2025.03.001","DOIUrl":"10.1016/j.diii.2025.03.001","url":null,"abstract":"<div><h3>Purpose</h3><div>The purpose of this study was to evaluate the feasibility and the accuracy of myocardial late iodine enhancement for extracellular volume (ECV) quantification using dual-source photon-counting detector computed tomography (PCD-CT) in patients with suspected acute myocarditis by comparison with cardiac MRI.</div></div><div><h3>Materials and methods</h3><div>Patients with clinical suspicion of myocarditis who were referred for coronary CT angiography (CCTA) to exclude coronary artery disease were included in this retrospective study. All patients underwent CCTA examination using a first-generation PCD-CT, which included slate iodine enhancement images. ECV was calculated from the iodine ratio of the myocardium to the blood pool on late iodine enhancement PCD-CT images. A comprehensive cardiac MRI protocol was used as the reference method to confirm myocarditis according to the Lake Louise 2018 criteria. All subjects underwent CCTA using PCD-CT and cardiac MRI within 24 h. The mean dose-length product of late enhancement PCD-CT scanning was calculated. Correlations between ECV PCD-CT (endocardial, epicardial, midcardial, and global), cardiac MRI-LGE, and right and left ventricular ejection fractions were assessed using Pearson correlation test. ECV values derived from PCD-CT and those from cardiac MRI were compared using Bland Altman plots and linear regression analysis. Areas under the receiver operating characteristic curves (AUCs) were used to determine the optimal thresholds of ECV-PCD-CT and ECV-MRI for differentiating patients with myocarditis from those not meeting the Lake Louise criteria.</div></div><div><h3>Results</h3><div>Thirty-two patients were included. There were 19 men and 13 women with a mean age of 35.9 ± 15.0 (standard deviation [SD]) years; age range: 21–51). The mean dose-length product of late enhancement PCD-CT scanning was 96 ± 32 (SD) mGy.cm. No significant differences in mean global ECV were found between ECV calculated with the PCD-CT (29.4 ± 4.5 [SD] %) and that calculated with cardiac MRI (30.0 ± 4.1 [SD] %) (<em>P</em> = 0.69). ECV-CT was greater in patients with cardiac MRI-confirmed myocarditis (31.65 ± 3.6 [SD] %) by comparison with those with normal findings (25.6 ± 3.2 [SD] %) (<em>P</em> &lt; 0.01). ECV-CT strongly correlated with LGE mass (<em>r</em> = 0.82) and showed strong segmental correlation with ECV-MRI (basal: <em>r</em> = 0.95; mid-ventricular: <em>r</em> = 0.91). An ECV-CT threshold of 26.9 % yielded an AUC of 0.95 (95 % CI: 0.84–1.00) for the diagnosis of myocarditis.</div></div><div><h3>Conclusion</h3><div>Calculation of ECV using iodine maps derived from late iodine enhancement cardiac PCD-CT images is both feasible and accurate at low radiation doses. PCD-CT appears as a promising non-invasive imaging modality for the diagnostic and prognostic assessment of acute myocarditis in the setting of chest pain.</div></div>","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"106 7","pages":"Pages 255-263"},"PeriodicalIF":4.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143659125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiac magnetic resonance imaging in the follow-up of patients with Fabry cardiomyopathy","authors":"Jules Senlis ,&nbsp;Fabien Labombarda ,&nbsp;Julien Burel ,&nbsp;Arthur Flouriot ,&nbsp;Sébastien Normant ,&nbsp;Matthieu Demeyere ,&nbsp;Olivier Lairez ,&nbsp;Soraya El Ghannudi ,&nbsp;Alexis Jacquier ,&nbsp;Olivier Ghekiere ,&nbsp;Farah Cadour ,&nbsp;Jean-Nicolas Dacher","doi":"10.1016/j.diii.2025.02.002","DOIUrl":"10.1016/j.diii.2025.02.002","url":null,"abstract":"<div><h3>Purpose</h3><div>The purpose of this study was to evaluate the role of cardiac magnetic resonance imaging (MRI) in the follow-up of patients with Fabry disease. Our hypothesis was that LV functional parameters and native myocardial T1 and T2 values could be used to monitor treatment efficacy.</div></div><div><h3>Materials and methods</h3><div>This prospective, observational, multicenter study included patients with Fabry disease who underwent two cardiac MRI examinations performed at 1.5 T 24 months apart at five University Hospitals between March 2017 and December 2022. Changes in cardiac MRI parameters were compared between two groups of patients according to whether or not they were receiving specific treatment.</div></div><div><h3>Results</h3><div>Twenty-six patients with Fabry disease were enrolled. There were 17 women and 9 men, with a mean age of 45.3 ± 17.4 (standard deviation [SD]) years. Both treated and untreated patients showed an increase in native T1 values over time, but the T1 increase was higher in treated patients (global T1, +39.4 ± 28.9 [SD] ms) than in untreated ones (global T1, +14.5 ± 30.3 [SD] ms) (<em>P</em> = 0.04). T2 values decreased in treated patients (global T2, -2.11 [SD] ms ± 3.36 but increased in untreated ones (global T2, +0.57 ± 1.63 [SD] ms) (<em>P</em> = 0.02). No significant changes in extracellular cardiac volume, left ventricular functional parameters, late gadolinium enhancement or left atrial volume were observed. However, LV mass index increased in untreated patients and decreased in treated patients. Intra- and interobserver reproducibility of T1 measurements showed mean biases of -0.18 ms (limit of agreement:11.61, 11.24) and -0.64 ms (limit of agreement:23.82; 22.54), respectively.</div></div><div><h3>Conclusion</h3><div>Variations in native myocardial T1 values at cardiac MRI are significantly greater in patients with Fabry disease receiving treatment than in untreated patients, suggesting an effect of treatment on lipid storage. In addition, changes in T2 values suggest an anti-inflammatory effect of the treatment.</div></div>","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"106 7","pages":"Pages 247-254"},"PeriodicalIF":4.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiac MRI in Fabry disease: T1 mapping as a quantitative biomarker for treatment monitoring","authors":"Jean-Francois Deux ,&nbsp;Paul Habert","doi":"10.1016/j.diii.2025.04.005","DOIUrl":"10.1016/j.diii.2025.04.005","url":null,"abstract":"","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"106 7","pages":"Pages 243-244"},"PeriodicalIF":4.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143992955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unicentric Castleman disease: CT and cinematic rendering imaging features","authors":"Taha M. Ahmed,&nbsp;Elliot K. Fishman","doi":"10.1016/j.diii.2025.05.001","DOIUrl":"10.1016/j.diii.2025.05.001","url":null,"abstract":"","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"106 7","pages":"Pages 280-281"},"PeriodicalIF":4.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144182690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unveiling an under-recognized strain: New guidelines for pelvic congestion syndrome.","authors":"Maxime Barat, Philippe Soyer, Anthony Dohan","doi":"10.1016/j.diii.2025.06.001","DOIUrl":"https://doi.org/10.1016/j.diii.2025.06.001","url":null,"abstract":"","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144508933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reevaluating the dominant sequence paradigm: Toward a comprehensive scoring model for PI-RADS.","authors":"Sébastien Molière, Raphaële Renard-Penna","doi":"10.1016/j.diii.2025.05.009","DOIUrl":"10.1016/j.diii.2025.05.009","url":null,"abstract":"","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2025-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144340513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"AI in radiology: Powerful, promising… but alarmingly hackable.","authors":"Augustin Lecler, Philippe Soyer","doi":"10.1016/j.diii.2025.06.003","DOIUrl":"https://doi.org/10.1016/j.diii.2025.06.003","url":null,"abstract":"","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2025-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144369438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Baseline CT-derived tumor burden and liquid biopsy as biomarkers to predict survival in patients with metastatic solid cancer.","authors":"Ghina Jardali, Littisha Lawrance, Lama Dawi, Jules Dupont, Othilie Gautier, Michèle Kind, Samy Ammari, Joya Hadchiti, Aurélie Choucair, Arnaud Bayle, Paul-Henry Cournède, Isabelle Borget, Serge Muller, François Bidault, Corinne Balleyguier, Antoine Hollebecque, Yohann Loriot, Filippo Gustavo Dall-Olio, Benjamin Besse, Ludovic Lacroix, Etienne Rouleau, Alexandre Bône, Fabrice André, Christophe Massard, Fabrice Barlesi, Antoine Italiano, Nathalie Lassau","doi":"10.1016/j.diii.2025.06.002","DOIUrl":"https://doi.org/10.1016/j.diii.2025.06.002","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to evaluate baseline tumor burden from liquid biopsy (LB) and computed tomography (CT) as prognostic biomarkers and whether their combination refines stratification in metastatic solid cancers.</p><p><strong>Materials and methods: </strong>This retrospective cohort study included 1065 patients. Eligible patients underwent LB and chest-abdomen-pelvis CT examination at baseline. Radiologists outlined lesions on the largest axial slice, and total tumor volume (TTV) was approximated in three dimensions. LB Tumor fraction (TF) ≥ 10 % was considered high. To assess combined prognostic power of LB and TTV, patients were divided into three groups according to LB (circulating tumor deoxyribonucleic acid [ctDNA] detectability and TF) and each group was further divided into two subgroups using TTV thresholds determined by Youden's index. Overall survival (OS) analyses were performed using Cox proportional hazard models and Kaplan-Meier curves.</p><p><strong>Results: </strong>A total of 560 patients (290 women and 270 men; median age, 61 years) with 31,314 annotated lesions were selected. The median OS was 11.28 months, and the median TTV was 96.68 cm³. The LB groups included patients with undetectable ctDNA (n = 102), patients with detectable ctDNA and low TF (n = 251), and patients with high TF (n = 207). Integrating TTV thresholds (18.7 cm³, 44.9 cm³, and 159.94 cm³) to LB groups significantly stratified the population on OS. Patients with undetectable ctDNA and TTV ≥ 18.7 cm³ had significantly shorter OS (median OS, 24.8 months) than those with TTV < 18.7 cm³ (median OS, > 35 months).</p><p><strong>Conclusion: </strong>Combining baseline CT tumor burden with LB could be a valuable prognostic tool for stratifying patients with metastatic solid cancer.</p>","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2025-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144250459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"3D post-processing in postmortem forensic imaging: Techniques, applications, and future directions.","authors":"Nicolas Douis, Elodie Marchand, Gwendoline Wary, Romain Gillet, Martin Kolopp, Alain Blum, Laurent Martrille","doi":"10.1016/j.diii.2025.05.007","DOIUrl":"https://doi.org/10.1016/j.diii.2025.05.007","url":null,"abstract":"<p><p>Three-dimensional (3D) post-processing is now an essential part of postmortem forensic computed tomography (CT) imaging. Recent advances in this field include the development of sophisticated reconstruction algorithms, such as global illumination rendering. These tools enable the photorealistic, synthetic, and selective visualization of complex anatomical information with high degrees of accuracy. This technology is particularly valuable in bone injury cases because it facilitates lesion mechanism analysis. 3D representations are valuable tools in forensic investigations, including radiological analysis, communicating results, preparing autopsies, and presenting forensic findings in court. Several factors influence the quality of the final 3D representation, including the technical parameters of CT data acquisition and the appropriate use of post-processing software. This review provides an overview of the key factors that determine the quality of 3D forensic CT images, examines their applications and limitations, and discusses future directions.</p>","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144227265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Normal variations of myocardial T1, T2 and T2* values at 1.5 T cardiac MRI in sex-matched healthy volunteers","authors":"Farah Cadour ,&nbsp;Jérôme Caudron ,&nbsp;André Gillibert ,&nbsp;Sébastien Normant ,&nbsp;Jean-Nicolas Dacher","doi":"10.1016/j.diii.2025.01.005","DOIUrl":"10.1016/j.diii.2025.01.005","url":null,"abstract":"<div><h3>Purpose</h3><div>The purpose of this study was to determine the normal variations of myocardial T1, T2, and T2* relaxation times on cardiac MRI obtained at 1.5 T in healthy, sex-balanced volunteers aged between 18 and 69 years.</div></div><div><h3>Material and methods</h3><div>A total of 172 healthy volunteers were recruited prospectively. They were further divided into seven sex-balanced age groups (18–19 years, 20–24 years, 25–29 years, 30–39 years, 40–49 years, 50–59 years, and 60–69 years). T1, T2, and T2* mapping were acquired in a single short-axis slice at the mid-level of the left ventricle. Global T1, T2, and T2* values were the mean of all segments. Comparisons between females and males were performed in each age group using independent samples <em>t</em>-test or Wilcoxon rank sum test, as appropriate. Multivariable linear effects models were used to analyze the effect of heart rate, body mass index, left ventricular mass, age, and sex on T1, T2, and T2* values. Inter- and intra-observer correlation (ICC) was evaluated.</div></div><div><h3>Results</h3><div>A total of 172 healthy participants were included. There were 83 males and 89 females, with a mean age of 37.3 ± 15.6 (standard deviation [SD]) years. Females had greater T1 values (980.9 ± 26.2 [SD] ms) compared to males (949.7 ± 18.3 [SD] ms) (<em>P</em> &lt; 0.001). T1 values decreased with age (974.3 ± 26.97 [SD] ms when ≤ 39 years vs<em>.</em> 954.4 ± 24.12 [SD] ms when &gt; 39 years; <em>P</em> &lt; 0.001), with smaller sex-related differences in older participants. Male sex and age were independently associated with lower values of T1 mapping. Age in females was independently associated with lower T1, T2, and T2* values. Moderate to good inter- and intra-observer agreement was found for T1, T2, and T2* (ICC ranging from 0.72 to 0.89).</div></div><div><h3>Conclusion</h3><div>T1, T2, and T2* values are influenced by age and sex, emphasizing the need to read and calibrate MRI values with respect to patient characteristics to avoid misdiagnosis.</div></div>","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"106 6","pages":"Pages 217-225"},"PeriodicalIF":4.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143048091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}