用于加速高分辨率上腹部磁共振成像的深度学习重建技术可在不耽误时间的情况下改进病灶检测。

IF 4.9 2区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Diagnostic and Interventional Imaging Pub Date : 2025-03-01 DOI:10.1016/j.diii.2024.09.008

Jan M. Brendel , Johann Jacoby , Reza Dehdab , Judith Herrmann , Stephan Ursprung , Sebastian Werner , Sebastian Gassenmaier , Dominik Nickel , Konstantin Nikolaou , Saif Afat , Haidara Almansour

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引用次数: 0

摘要

目的：本研究旨在比较传统T1加权容积插值屏气检查（VIBE）序列与DL重建加速高分辨率VIBE序列（HR-VIBEDL）在图像质量、病变清晰度和病变检测方面的差异：前瞻性招募了 2023 年 12 月至 2024 年 3 月期间在一家三级中心接受上腹部 MRI 检查的连续患者。参与者接受了 1.5 T 上腹部磁共振成像，采集了光谱脂肪饱和未增强和钆喷酸增强的常规 VIBE（四倍加速，3.0 毫米切片厚度，72 个轴向切片）和 HR-VIBEDL（六倍加速，2.0 毫米，108 个切片）。两个序列的采集时间相同，均为 16 秒。图像分析由三名读片员以盲法和随机法进行，内容涉及图像质量、病变的明显性以及肝脏、胰腺、脾脏、淋巴结和肾上腺的病变检测。采用重复测量方差分析比较了图像质量参数。病变检出率采用费舍尔精确检验进行比较。使用 Fleiss κ 检验评估阅读者之间的一致性：在 744 名连续患者中，有 50 人接受了评估。其中男性 30 人，女性 20 人，平均年龄为 60 ± 15（标准差 [SD]）岁（年龄范围：18-88 岁）。与传统的 VIBE 图像相比，HR-VIBEDL 图像的信噪比和边缘锐利度更高（P < 0.001），读片者之间的一致性也更高（κ：0.70-0.90）。与传统 VIBE 图像（3.21 ± 0.98 [SD]）相比，HR-VIBEDL 图像的病灶清晰度更高（3.50 ± 0.83 [SD]）（P = 0.005）。上腹部病变共有 171 个，三位读者的总病变数为 513 个。与传统 VIBE 图像（93.2%；478/513）相比，HR-VIBEDL 图像的病灶检出率更高（97.5%；500/513）（P = 0.002）：结论：与传统 VIBE 图像相比，上腹部 HR-VIBEDL 图像具有更高的图像质量、更好的病灶清晰度和更高的病灶检出率，而且不会耽误时间。

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Deep learning reconstruction for accelerated high-resolution upper abdominal MRI improves lesion detection without time penalty

Purpose

The purpose of this study was to compare a conventional T1-weighted volumetric interpolated breath-hold examination (VIBE) sequence with a DL-reconstructed accelerated high-resolution VIBE sequence (HR-VIBE_DL) in terms of image quality, lesion conspicuity, and lesion detection.

Materials and methods

Consecutive patients referred for upper abdominal MRI between December 2023 and March 2024 at a single tertiary center were prospectively enrolled. Participants underwent 1.5 T upper abdominal MRI with acquisition of spectrally fat-saturated unenhanced and gadobutrol-enhanced conventional VIBE (fourfold acceleration, 3.0 mm slice thickness, 72 axial slices) and HR-VIBE_DL (sixfold acceleration, 2.0 mm, 108 slices). Both sequences had an identical acquisition time of 16 s. Image analysis was performed by three readers in a blinded and randomized fashion, with respect to image quality, lesion conspicuity, and lesion detection in liver, pancreas, spleen, lymph nodes and adrenal glands. Image quality parameters were compared using repeated measures analysis of variance. Lesion detection rates were compared using Fisher exact test. Inter-reader agreement was assessed using Fleiss κ test.

Results

Among 744 consecutive patients, 50 participants were evaluated. There were 30 men and 20 women, with a mean age of 60 ± 15 (standard deviation [SD]) years (age range: 18–88 years). HR-VIBE_DL images demonstrated superior signal-to-noise ration and edge sharpness by comparison with conventional VIBE images (P < 0.001 for both), with substantial interreader agreement (κ: 0.70–0.90). Lesion conspicuity was higher with for HR-VIBE_DL images (3.50 ± 0.83 [SD]) by comparison with conventional VIBE images (3.21 ± 0.98 [SD]) (P = 0.005). There were 171 upper abdominal lesions, yielding a total of 513 for all three readers. HR-VIBE_DL images yielded higher lesion detection rate (97.5 %; 500/513) compared to conventional VIBE images (93.2 %; 478/513) (P = 0.002).

Conclusion

HR-VIBE_DL images of the upper abdomen result in superior image quality, better lesion conspicuity, and improved lesion detection without time penalty by comparsion with conventional VIBE images.

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来源期刊

Diagnostic and Interventional Imaging Medicine-Radiology, Nuclear Medicine and Imaging

CiteScore

8.50

自引率

29.10%

发文量

126

审稿时长

11 days

期刊介绍： Diagnostic and Interventional Imaging accepts publications originating from any part of the world based only on their scientific merit. The Journal focuses on illustrated articles with great iconographic topics and aims at aiding sharpening clinical decision-making skills as well as following high research topics. All articles are published in English. Diagnostic and Interventional Imaging publishes editorials, technical notes, letters, original and review articles on abdominal, breast, cancer, cardiac, emergency, forensic medicine, head and neck, musculoskeletal, gastrointestinal, genitourinary, interventional, obstetric, pediatric, thoracic and vascular imaging, neuroradiology, nuclear medicine, as well as contrast material, computer developments, health policies and practice, and medical physics relevant to imaging.