Biology-Basel最新文献_第4页

The Sublethal Effects of Neonicotinoids on Honeybees. 新烟碱类杀虫剂对蜜蜂的亚致死效应。

IF 3.5 3区生物学

Biology-Basel Pub Date : 2025-08-18 DOI: 10.3390/biology14081076

Zunair Ahsan, Zhijia Wu, Zheguang Lin, Ting Ji, Kang Wang

{"title":"The Sublethal Effects of Neonicotinoids on Honeybees.","authors":"Zunair Ahsan, Zhijia Wu, Zheguang Lin, Ting Ji, Kang Wang","doi":"10.3390/biology14081076","DOIUrl":"10.3390/biology14081076","url":null,"abstract":"Honeybees (Apis mellifera) are indispensable pollinators vital to global biodiversity, ecosystem stability, and agricultural productivity, and they promote over 35% of food crops and 75% of flowering plants. Yet, they are in unprecedented decline, partly as a result of neonicotinoid pesticide use elsewhere. These effects on honey bee health are synthesized in this paper through molecular, physiological, and behavioral data showing that sublethal effects of neonicotinoids impair honey bee health. As neurotoxic insecticides that target nicotinic acetylcholine receptors (nAChRs), these insecticides interfere with neurotransmission and underlie cognitive impairment, immune suppression, and oxidative stress. Developmental toxicity is manifested in larvae as retarded growth, reduced feeding, and increased death; queen and drone reproduction are impaired, lowering colony viability. As a result, adult bees have shortened lives and erratic foraging, are further disoriented, and experience impaired navigation, communication, and resource collection. Together, these effects cascade to reduced brood care, thermoregulatory failure, and heretofore unrecognized increased susceptibility to pathogens, increasing the probability of colony collapse at the colony level. Contaminants such as pesticides may cause pollinator exposure and, in turn, may cause their population to be undermined if they are not mitigated; therefore, urgent mitigation strategies, including integrated pest management (IPM), regulatory reforms, and adoption of biopesticides, are needed to mitigate pollinator exposure. The focus of this review lies in the ecological necessity of restructuring how agriculture is managed to simultaneously meet food security and the conservation of honeybee health, the linchpin of global ecosystems.","PeriodicalId":48624,"journal":{"name":"Biology-Basel","volume":"14 8","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12383910/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144994092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Qualitative Analysis of a Nonautonomous Delayed Stochastic Predator-Prey Model with Beddington-DeAngelis Functional Response. 具有Beddington-DeAngelis功能响应的非自治延迟随机捕食-食饵模型的定性分析。

IF 3.5 3区生物学

Biology-Basel Pub Date : 2025-08-18 DOI: 10.3390/biology14081078

Lili Jia, Changyou Wang

引用次数: 0

From Panels to Pathogen Networks: The Expanding Role of Targeted Sequencing in Veterinary Medicine. 从小组到病原体网络：目标测序在兽医学中的扩展作用。

IF 3.5 3区生物学

Biology-Basel Pub Date : 2025-08-18 DOI: 10.3390/biology14081075

Jiali Luo, Wentao Lu, Ruiting Liu, Shukai Zhang, Jie Cao, Chong Ma

{"title":"From Panels to Pathogen Networks: The Expanding Role of Targeted Sequencing in Veterinary Medicine.","authors":"Jiali Luo, Wentao Lu, Ruiting Liu, Shukai Zhang, Jie Cao, Chong Ma","doi":"10.3390/biology14081075","DOIUrl":"10.3390/biology14081075","url":null,"abstract":"Targeted sequencing, a pivotal branch of next-generation sequencing (NGS), enables the selective enrichment of specific genomic regions and has demonstrated significant advantages in the detection of animal pathogens. This review systematically explores the underlying principles of targeted sequencing, various enrichment strategies-including PCR amplification, probe hybridization, and CRISPR-Cas systems-and their key applications in veterinary pathogen diagnostics. Due to its high throughput, sensitivity, and cost-effectiveness, targeted sequencing has been successfully applied in the multiplex detection of pathogens in economically significant livestock, such as cattle, as well as in the surveillance of antimicrobial resistance (AMR) genes, pathogen typing, and source tracing. It is particularly effective in identifying mixed infections and low-abundance pathogens. Nonetheless, wide application is restricted by some factors, like incomprehensive reference databases, cost-effectiveness, and limited application in primary-level laboratories. Further development directions are AI-based panel design, multimodal diagnostic platform integration, standard workflow construction, and introduction of a multi-omics method. Such progress focuses on enhancing the targeted sequencing scalability and precision consistent with the \"One Health\" initiative objective.","PeriodicalId":48624,"journal":{"name":"Biology-Basel","volume":"14 8","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12383765/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144993911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of Bacterial Population Changes and Ecological Dynamics in Oil-Impacted Soils Using 16S rRNA Amplicon Sequencing. 利用16S rRNA扩增子测序评价石油污染土壤细菌种群变化和生态动态

IF 3.5 3区生物学

Biology-Basel Pub Date : 2025-08-18 DOI: 10.3390/biology14081074

Teddie O Rahube, Ramganesh Selvarajan, Batendi Nduna, Bokani Nthaba, Loago Molwalefhe, Elisha Shemang

引用次数: 0

Assessing the Potential Distribution of the Traditional Chinese Medicinal Plant Spatholobus suberectus in China Under Climate Change: A Biomod2 Ensemble Model-Based Study. 气候变化背景下中国药用植物鸡血藤潜在分布评估：基于Biomod2集合模型的研究

IF 3.5 3区生物学

Biology-Basel Pub Date : 2025-08-17 DOI: 10.3390/biology14081071

Yijun Lin, Quanwei Liu, Shan Lv, Xiaoyu Huang, Chaoyang Wei, Jun Li, Yijie Guan, Yaxuan Pan, Yijia Mi, Yanshu Cheng, Xiangyu Yang, Danping Xu

{"title":"Assessing the Potential Distribution of the Traditional Chinese Medicinal Plant Spatholobus suberectus in China Under Climate Change: A Biomod2 Ensemble Model-Based Study.","authors":"Yijun Lin, Quanwei Liu, Shan Lv, Xiaoyu Huang, Chaoyang Wei, Jun Li, Yijie Guan, Yaxuan Pan, Yijia Mi, Yanshu Cheng, Xiangyu Yang, Danping Xu","doi":"10.3390/biology14081071","DOIUrl":"10.3390/biology14081071","url":null,"abstract":"Spatholobus suberectus, a valuable Chinese medicinal plant, faces habitat shifts under climate change. In order to better utilize the medicinal properties of S. suberectus and conduct further investigations, this study utilized the Biomod2 ensemble model to predict and analyze the potential expansion and contraction of suitable habitat areas for S. suberectus in China under changing climatic and environmental conditions. The results showed that, compared to the pre-screened models, the ensemble model significantly improved the prediction accuracy. Currently, S. suberectus is primarily distributed in southern China. Under the projected scenarios of SSP1-2.6, SSP2-4.5, and SSP5-8.5, its suitable habitat is expected to expand overall, with the increased areas concentrated mainly in southwestern, central, and eastern China. As climatic factors shift, the high-suitability center of S. suberectus is predicted to shift slightly southward under the SSP1-2.6 scenario, while under the SSP2-4.5 and SSP5-8.5 scenarios, it is projected to move northwestward. In the future, it will be necessary to optimize the warm and humid growth environment for cultivated S. suberectus in China. Meanwhile, wild S. suberectus populations should be closely monitored for the impact of climate change to prevent potential partial reductions in suitable habitats, thereby ensuring ecological balance and sustainable development.","PeriodicalId":48624,"journal":{"name":"Biology-Basel","volume":"14 8","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12383331/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144993856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of Decapitation on Chlorophyll Metabolism, Endogenous Hormones, and Tillering Ability in Pinus yunnanensis Seedlings of Different Ages. 无头处理对云南松苗叶绿素代谢、内源激素及分蘖能力的影响

IF 3.5 3区生物学

Biology-Basel Pub Date : 2025-08-17 DOI: 10.3390/biology14081070

Wei Li, Xin Su, Sili Cheng, Dan Wang, Yulan Xu, Nianhui Cai

{"title":"Effects of Decapitation on Chlorophyll Metabolism, Endogenous Hormones, and Tillering Ability in Pinus yunnanensis Seedlings of Different Ages.","authors":"Wei Li, Xin Su, Sili Cheng, Dan Wang, Yulan Xu, Nianhui Cai","doi":"10.3390/biology14081070","DOIUrl":"10.3390/biology14081070","url":null,"abstract":"Pinus yunnanensis is an essential tree species in southwest China. However, its genetic degeneration problem urgently needs to be addressed. Decapitation promotes seedling propagation primarily by disrupting apical dominance, triggering hormonal changes that stimulate lateral bud growth. To investigate the response of hormones and photosynthetic pigments in P. yunnanensis to decapitation at different seedling ages, seedlings aged 6, 10, 14, 18, and 30 months were used as materials to carry out unified decapitation treatment, and the dynamics of photosynthetic pigments, changes in endogenous hormones, and their relationship with tillering ability were analyzed. The results showed that the photosynthetic pigments were higher in younger decapitated seedlings than in older ones, and carotenoids showed an upward trend with time. Additionally, decapitation significantly altered the balance of endogenous hormones, including the contents of GAs, ABA, SA, JA, JA-Ile, and ACC. The GA3 and ABA contents in the middle-aged decapitated seedlings of P. yunnanensis were higher. The seedlings with older decapitation ages showed higher contents of IAA, SA, and JA. Overall, seedlings with different decapitation ages exhibit significant differences in their responses to decapitation, as indicated by variations in photosynthetic pigments and hormones. This research elucidated the optimal decapitation age for P. yunnanensis, providing a theoretical foundation for establishing efficient decapitation nurseries and promoting near-natural propagation.","PeriodicalId":48624,"journal":{"name":"Biology-Basel","volume":"14 8","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12383709/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144994069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Genome-Wide Association Study of Rib Number and Thoracolumbar Vertebra Number in a Landrace × Yorkshire Crossbred Pig Population. 长约克杂交猪肋数和胸腰椎数的全基因组关联研究。

IF 3.5 3区生物学

Biology-Basel Pub Date : 2025-08-16 DOI: 10.3390/biology14081068

Chunyan Bai, Junwen Fei, Xiaoran Zhang, Wuyang Liu, Juan Ke, Changyi Chen, Yu He, Shuang Liang, Boxing Sun, Hao Sun

{"title":"A Genome-Wide Association Study of Rib Number and Thoracolumbar Vertebra Number in a Landrace × Yorkshire Crossbred Pig Population.","authors":"Chunyan Bai, Junwen Fei, Xiaoran Zhang, Wuyang Liu, Juan Ke, Changyi Chen, Yu He, Shuang Liang, Boxing Sun, Hao Sun","doi":"10.3390/biology14081068","DOIUrl":"10.3390/biology14081068","url":null,"abstract":"The number of thoracolumbar vertebrae (NTLV) and the number of ribs (NR) are economically important traits in pigs due to their influence on carcass length and meat yield. Although VRTN is an established key gene, it fails to fully account for population-level variation in vertebral count, necessitating a further exploration of its genetic mechanisms. Given the efficacy of crossbred populations in mapping the genetic determinants of phenotypic variation, we analyzed 439 pigs from a Landrace × Yorkshire cross. Genotyping was performed via a 50 K SNP chip. Both NTLV and NR showed high heritability (0.700 and 0.752, respectively), while the number of lumbar vertebrae (NLV) showed limited variation (92.5% of pigs had NLV = 6). Using the BLINK model, four significant loci were identified. The most significant SNP, rs3469762345, located in the intergenic region between ABCD4 and VRTN, corresponds to a previously known QTL. Additionally, three novel variant sites (rs81211244, rs81347323, and rs81416674) were identified within or near the ALDH7A1, PTPRT, and PAK1 genes, which are known to play a role in bone development. This study uncovers novel swine candidate genes associated with vertebral and rib number variation, subsequently facilitating targeted research into their molecular mechanisms.","PeriodicalId":48624,"journal":{"name":"Biology-Basel","volume":"14 8","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12383743/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144993863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Burdock Tea Affects Pulmonary Microbiota and Physiology Through Short-Chain Fatty Acids in Wistar Rats. 牛蒡茶通过短链脂肪酸影响Wistar大鼠肺微生物群和生理。

IF 3.5 3区生物学

Biology-Basel Pub Date : 2025-08-16 DOI: 10.3390/biology14081064

Xiao-Feng Peng, Jing-Yi Zhu, Li-Zhi Cheng, Wan-Hong Wei, Sheng-Mei Yang, Xin Dai

{"title":"Burdock Tea Affects Pulmonary Microbiota and Physiology Through Short-Chain Fatty Acids in Wistar Rats.","authors":"Xiao-Feng Peng, Jing-Yi Zhu, Li-Zhi Cheng, Wan-Hong Wei, Sheng-Mei Yang, Xin Dai","doi":"10.3390/biology14081064","DOIUrl":"10.3390/biology14081064","url":null,"abstract":"The impact of burdock tea (BT) made from burdock (Arctium lappa) roots in normal individuals and animal models remains largely unknown, particularly on lung protection. This study examined responses of oxidative stress, inflammation, and the microbiota within the cecum and the lung to BT treatment in healthy Wistar rats. A middle-dose BT reduced the Chao1 and Shannon indices, and both low and middle doses induced structural alterations in the cecal microbiota. Additionally, low doses increased the abundances of Phascolarctobacterium, Alloprevotella, Desulfovibrio, and the NK4A214 group. In the lung, middle and high doses increased Corynebacterium, with high doses also boosting Megasphaera and Lactobacillus. Functionally, low doses downregulated the biosynthesis of antibiotics in the cecal microbiota, while middle doses reduced the Epstein-Barr virus and Escherichia coli pathogenic infection pathways; additionally, middle and high doses modulated chromosomal proteins and bile acid biosynthesis in the pulmonary microbiota. BT treatment enhanced the content of short-chain fatty acids (SCFAs), upregulated the expression of GPR43, and suppressed NLRP3 expression in both the colon and lung tissues, while concurrently promoting the expression of ZO-1 and Occludin. Furthermore, serum levels of IL-1β and IL-6, as well as tissue levels of MDA, were significantly reduced. Notably, propionate exhibited an inverse correlation with MDA, IL-6, and NLRP3, while showing a positive correlation with ZO-1. Similarly, acetate was negatively correlated with MDA and NLRP3 and positively correlated with ZO-1. Overall, BT exhibits a nontoxic profile and may protect lung tissue through its antioxidant nature and gut-lung axis mediated by SCFAs.","PeriodicalId":48624,"journal":{"name":"Biology-Basel","volume":"14 8","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12383450/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144994035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mapping Multi-Modal Fatigue in Elite Soccer Through Sweat-Omics Perspectives: A Narrative Review. 通过汗液组学视角绘制精英足球多模态疲劳：一个叙述性回顾。

IF 3.5 3区生物学

Biology-Basel Pub Date : 2025-08-16 DOI: 10.3390/biology14081069

Moses Gnanasigamani, Ersan Arslan, Yusuf Soylu, Bulent Kilit, Paweł Chmura

{"title":"Mapping Multi-Modal Fatigue in Elite Soccer Through Sweat-Omics Perspectives: A Narrative Review.","authors":"Moses Gnanasigamani, Ersan Arslan, Yusuf Soylu, Bulent Kilit, Paweł Chmura","doi":"10.3390/biology14081069","DOIUrl":"10.3390/biology14081069","url":null,"abstract":"Fatigue in elite soccer is a multifaceted phenomenon involving physical, metabolic, psychological, and neuromuscular stressors that accumulate over training and competition. Traditional monitoring tools, while informative, are often invasive, impractical during play, or fail to provide real-time insights. This narrative review synthesizes sweat-based biomarkers linked to fatigue in elite soccer, with a focus on multi-modal domains (neuromuscular, metabolic, inflammatory, psychological). Using an integrative approach, we reviewed studies published across databases including PubMed, Scopus, and Web of Science that evaluate sweat biomarkers of different types of fatigue in soccer. We identified key candidates-lactate, sodium, cortisol, IL-6, and hypoxanthine-and evaluated their potential in non-invasive monitoring. Youth-specific and female populations remain underrepresented. We also assessed each biomarker's technological maturity using a sweat-specific Technology Readiness Level (TRL) framework. Based on these findings, we propose a translational framework for practitioners and outline priorities for future research and validation in real-world sport settings.","PeriodicalId":48624,"journal":{"name":"Biology-Basel","volume":"14 8","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12383715/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144993422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mimicking Gastric Cancer Collagen Reorganization with Decellularized ECM-Based Scaffolds. 脱细胞ecm支架模拟胃癌胶原重组。

IF 3.5 3区生物学

Biology-Basel Pub Date : 2025-08-16 DOI: 10.3390/biology14081067

Néstor Corro, Sebastián Alarcón, Ángel Astroza, Roxana González-Stegmaier, Carolina Añazco

{"title":"Mimicking Gastric Cancer Collagen Reorganization with Decellularized ECM-Based Scaffolds.","authors":"Néstor Corro, Sebastián Alarcón, Ángel Astroza, Roxana González-Stegmaier, Carolina Añazco","doi":"10.3390/biology14081067","DOIUrl":"10.3390/biology14081067","url":null,"abstract":"The tumor microenvironment (TME) has a substantial impact on the progression of gastric cancer. Collagen, the most abundant protein in the extracellular matrix (ECM), forms a dense physical barrier that regulates anti-tumor immunity in the TME. It is a significant regulator of the signaling pathways of cancer cells, which are responsible for migration, proliferation, and metabolism. ECM proteins, particularly remodeling enzymes and collagens, can be modified to increase stiffness and alter the mechanical properties of the stroma. This, in turn, increases the invasive potential of tumor cells and resistance to immunotherapy. Given the dynamic nature of collagen, novel therapeutic strategies have emerged that target both collagen biosynthesis and degradation, processes that are essential for addressing ECM stiffening. This review delineates the upregulation of the expression and deposition of collagen, as well as the biological functions, assembly, and reorganization that contribute to the dissemination of this aggressive malignancy. Furthermore, the review emphasizes the importance of creating 3D in vitro models that incorporate innovative biomaterials that avoid the difficulties of traditional 2D culture in accurately simulating real-world conditions that effectively replicate the distinctive collagen microenvironment. Ultimately, it investigates the use of decellularized ECM-derived biomaterials as tumor models that are designed to precisely replicate the mechanisms associated with the progression of stomach cancer.","PeriodicalId":48624,"journal":{"name":"Biology-Basel","volume":"14 8","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12383932/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144994026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0