Biology-Basel最新文献_第5页

Potential Interactions Between Soil-Transmitted Helminths and Herpes Simplex Virus Type II: Implications for Sexual and Reproductive Health in Sub-Saharan African.

IF 3.6 3区生物学

Biology-Basel Pub Date : 2024-12-15 DOI: 10.3390/biology13121050

Roxanne Pillay, Pragalathan Naidoo, Zamathombeni Duma, Khethiwe N Bhengu, Miranda N Mpaka-Mbatha, Nomzamo Nembe-Mafa, Zilungile L Mkhize-Kwitshana

{"title":"Potential Interactions Between Soil-Transmitted Helminths and Herpes Simplex Virus Type II: Implications for Sexual and Reproductive Health in Sub-Saharan African.","authors":"Roxanne Pillay, Pragalathan Naidoo, Zamathombeni Duma, Khethiwe N Bhengu, Miranda N Mpaka-Mbatha, Nomzamo Nembe-Mafa, Zilungile L Mkhize-Kwitshana","doi":"10.3390/biology13121050","DOIUrl":"https://doi.org/10.3390/biology13121050","url":null,"abstract":"Sub-Saharan Africa (SSA) bears a disproportionate and overlapping burden of soil-transmitted helminths (STHs) and sexually transmitted viral infections. An estimated 232 million pre-school and school-aged children in SSA are vulnerable to STH infections. Together with this, SSA has a high prevalence of herpes simplex virus type II (HSV-2), the primary cause of genital herpes. Studies have examined the immunological interactions between STHs and human immunodeficiency virus and human papillomavirus during co-infections. However, epidemiological and immunological studies on STH-HSV-2 co-infections are lacking, therefore their impact on sexual and reproductive health is not fully understood. STH-driven Th2 immune responses are known to downregulate Th1/Th17 immune responses. Therefore, during STH-HSV-2 co-infections, STH-driven immune responses may alter host immunity to HSV-2 and HSV-2 pathology. Herein, we provide an overview of the burden of STH and HSV-2 infections in SSA, and host immune responses to STH and HSV-2 infections. Further, we emphasize the relevance and urgent need for (i) focused research into the interactions between these important pathogens, and (ii) integrated approaches to improve the clinical detection and management of STH-HSV-2 co-infections in SSA.","PeriodicalId":48624,"journal":{"name":"Biology-Basel","volume":"13 12","pages":""},"PeriodicalIF":3.6,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11673149/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142957218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of Arsenic Stress on the Antioxidant System and Photosystem of Arthrospira platensis.

IF 3.6 3区生物学

Biology-Basel Pub Date : 2024-12-15 DOI: 10.3390/biology13121049

Jiawei Liu, Jie Du, Di Wu, Xiang Ji, Xiujuan Zhao

{"title":"Impact of Arsenic Stress on the Antioxidant System and Photosystem of Arthrospira platensis.","authors":"Jiawei Liu, Jie Du, Di Wu, Xiang Ji, Xiujuan Zhao","doi":"10.3390/biology13121049","DOIUrl":"https://doi.org/10.3390/biology13121049","url":null,"abstract":"Arthrospira platensis exhibits high tolerance to arsenic; however, the mechanisms underlying its response to the arsenic stress have not been fully elucidated. This study investigated the growth and resistance mechanisms of A. platensis under As3+ stress by measuring physiological and biochemical indices, conducting transcriptome sequencing, and validating the results through qPCR. The findings show that arsenic stress affected the antioxidant system and photosynthetic pigment synthesis in A. platensis. The algae mitigated arsenic-induced oxidative stress by increasing cellular metabolic rates, enhancing cell wall stability, and reducing membrane lipid peroxidation. Transcriptome analysis revealed that pathways related to oxidative phosphorylation and chlorophyll degradation were upregulated under arsenic stress, while the expression of membrane transporters was significantly downregulated. Additionally, the algae alleviated arsenic stress by producing hydrogen and polyamine compounds. This study provides insights into the mechanisms of A. platensis response to arsenic stress and elucidates the molecular pathways involved in the stress response to As3+.","PeriodicalId":48624,"journal":{"name":"Biology-Basel","volume":"13 12","pages":""},"PeriodicalIF":3.6,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11673294/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142957168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Abundance, Size Structure, and Growth of the Invasive Blue Crab Callinectes sapidus in the Lesina Lagoon, Southern Adriatic Sea.

IF 3.6 3区生物学

Biology-Basel Pub Date : 2024-12-15 DOI: 10.3390/biology13121051

Giorgio Mancinelli, Nicola Lago, Tommaso Scirocco, Oscar Antonio Lillo, Raffaele De Giorgi, Lorenzo Doria, Emanuele Mancini, Francesco Mancini, Luigi Potenza, Lucrezia Cilenti

{"title":"Abundance, Size Structure, and Growth of the Invasive Blue Crab Callinectes sapidus in the Lesina Lagoon, Southern Adriatic Sea.","authors":"Giorgio Mancinelli, Nicola Lago, Tommaso Scirocco, Oscar Antonio Lillo, Raffaele De Giorgi, Lorenzo Doria, Emanuele Mancini, Francesco Mancini, Luigi Potenza, Lucrezia Cilenti","doi":"10.3390/biology13121051","DOIUrl":"https://doi.org/10.3390/biology13121051","url":null,"abstract":"The fishery biology of the invasive Atlantic blue crab Callinectes sapidus in the Mediterranean Sea outside the eastern sectors of the basin has been only recently investigated. Here we studied the population of C. sapidus in the Lesina Lagoon (Adriatic Sea, SE Italy). In total, 838 crabs were captured monthly between February 2021 and January 2022 using fyke nets. Abundances varied seasonally with catches per unit effort ranging between 0 and 1.76 crabs fyke nets-1 d-1 in winter and summer. Spatial abundances estimated in summer by a Carle-Strub procedure ranged between 0.06 and 0.64 crabs m-2. The sex ratio (♂/♀) was close to 1:1; males prevailed only in August and September; ovigerous females occurred from April to August. The males' size at morphological maturity was smaller than females (110.6-112.3 mm vs. 122.1-123.1 mm). Seasonal von Bertalanffy growth parameters indicated that, compared with males, females showed a shorter maximum lifespan (5 vs. 8 years), a higher growth coefficient K (0.6 vs. 0.4 y-1) and growth performance index Ф' (4.6 vs. 4.3), while maximum sizes CW∞ (237.8 vs. 232.6 mm) and seasonality indices C (0.62 vs. 0.57) were similar. Furthermore, females showed higher natural and fishing mortalities and exploitation rate. We discussed the results of the present study in the context of the available literature to provide a valuable basis for the implementation of standardized Mediterranean-scale management plans, matching exploitation of C. sapidus with sustainable conservation of coastal ecosystems.","PeriodicalId":48624,"journal":{"name":"Biology-Basel","volume":"13 12","pages":""},"PeriodicalIF":3.6,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11673200/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142956809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Eggshell Quality Traits and Transcriptome Gene Screening Between Yunnong and Jingfen Chicken Breeds.

IF 3.6 3区生物学

Biology-Basel Pub Date : 2024-12-14 DOI: 10.3390/biology13121048

Zijian Li, Hao Wu, Jing Fu, Maida Mushtaq, Muhammad Khan, Yong Liu, Zobia Azeem, Hongmei Shi, Yang He, Ru Zhang, Muhammad Aziz Ur Rahman, Jiajia Kang, Changrong Ge, Kun Wang

{"title":"Eggshell Quality Traits and Transcriptome Gene Screening Between Yunnong and Jingfen Chicken Breeds.","authors":"Zijian Li, Hao Wu, Jing Fu, Maida Mushtaq, Muhammad Khan, Yong Liu, Zobia Azeem, Hongmei Shi, Yang He, Ru Zhang, Muhammad Aziz Ur Rahman, Jiajia Kang, Changrong Ge, Kun Wang","doi":"10.3390/biology13121048","DOIUrl":"https://doi.org/10.3390/biology13121048","url":null,"abstract":"The eggshell quality traits in avian species, including Yunnong chickens (YN), are crucial for commercial and breeding purposes. The use of advanced biotechnologies, such as gene sequencing, has become increasingly common for identifying genetic markers and comparing specific traits in livestock. However, genetic markers related to eggshell traits in YN chickens remain unexplored. This study aimed to compare eggshell quality traits and identify genetic markers in YN chickens versus commercial Jingfen chickens (JF). A total of 400 chicks (200 per breed) were reared for 300 days under controlled conditions. At the end, 60 eggs from each breed were analyzed using scanning electron microscopy to examine eggshell cross-sections and mammillary layer structure. Tissue samples from kidneys and eggshell glands were collected from six hens per breed for RT-qPCR analysis to study gene expression profiles. Results showed that YN chickens had significantly higher eggshell strength, thickness, mammillary density, and effective layer thickness than JF chickens (p < 0.01). Despite this, YN chickens had a thinner mammillary layer. RT-qPCR analysis confirmed five candidate genes related to eggshells (LSS, NSDHL, MSMO1, SQLE, and FDFT1) that play an important role in this process. Pathway analysis revealed significant enrichment in several biological processes, including steroid biosynthesis, glycerolipid metabolism, purine metabolism, and thiamine metabolism. Based on these results, the YN chickens have strong eggshells with better thickness, mammillary density, and effective layer thickness. In addition, genomic and pathways analysis suggest a complex interaction of metabolic, immune, and cellular processes potentially influencing eggshell quality traits in poultry.","PeriodicalId":48624,"journal":{"name":"Biology-Basel","volume":"13 12","pages":""},"PeriodicalIF":3.6,"publicationDate":"2024-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11673107/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142957077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring the Adaptation Process of Huso dauricus to High Temperatures Based on Changes in Intestinal Microbiota.

IF 3.6 3区生物学

Biology-Basel Pub Date : 2024-12-13 DOI: 10.3390/biology13121045

Ruoyu Wang, Yutao Li, Yining Zhang, Sihan Wang, Zheng He, Dingchen Cao, Zhipeng Sun, Nianmin Wang, Ying Zhang, Bo Ma

{"title":"Exploring the Adaptation Process of Huso dauricus to High Temperatures Based on Changes in Intestinal Microbiota.","authors":"Ruoyu Wang, Yutao Li, Yining Zhang, Sihan Wang, Zheng He, Dingchen Cao, Zhipeng Sun, Nianmin Wang, Ying Zhang, Bo Ma","doi":"10.3390/biology13121045","DOIUrl":"https://doi.org/10.3390/biology13121045","url":null,"abstract":"Global warming has led to rising water temperatures, posing a significant threat to fish survival. Understanding the mechanisms by which fish respond to and adapt to temperature variations is thus of considerable importance. This study employed high-throughput 16S rRNA gene sequencing and bioinformatics to investigate changes in the intestinal microbiota of the kaluga sturgeon (Huso dauricus) under four temperature conditions (19 °C, 25 °C, 28 °C, and 31 °C) and its relationship with adaptation to high-temperature stress. The results indicated that temperature variations caused significant changes in the intestinal microbiota. Over time, differences in the microbiota structure became more pronounced under different temperature conditions, and within-group variability gradually decreased. At higher temperatures, the relative abundance of Sphingomonas significantly decreased, while that of Clostridium sensu stricto 1, Cetobacterium, and Plesiomonas exhibited a significant increase in relative abundance. Upon the cessation of rapid mortality under various high-temperature conditions, the intestinal microbiota structure and composition became highly similar, with Clostridium sensu stricto 1 dominating both in terms of composition and relative abundance, suggesting a central role in adaptation to high-temperature stress. This study preliminarily confirms that the high-temperature adaptability of Huso dauricus is closely related to the structure and composition of its intestinal microbiota, with bacteria such as Clostridium sensu stricto 1 playing an important role. These findings provide new scientific insights into enhancing fish adaptability to high-temperature stress.","PeriodicalId":48624,"journal":{"name":"Biology-Basel","volume":"13 12","pages":""},"PeriodicalIF":3.6,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11672952/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142957093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Insights into the Biotic Factors Shaping Ectomycorrhizal Associations.

IF 3.6 3区生物学

Biology-Basel Pub Date : 2024-12-13 DOI: 10.3390/biology13121044

Belkacem El Amrani

引用次数: 0

Exploring the Potent Roles of an Internally Translated Truncated Connexin-43 Isoform.

IF 3.6 3区生物学

Biology-Basel Pub Date : 2024-12-13 DOI: 10.3390/biology13121046

Mario Maalouf, Adelaide T Gaffney, Bridger R Bell, Robin M Shaw

引用次数: 0

The Unique Roles of Ion Channels in Pluripotent Stem Cells in Response to Biological Stimuli.

IF 3.6 3区生物学

Biology-Basel Pub Date : 2024-12-13 DOI: 10.3390/biology13121043

Taku Kaitsuka

引用次数: 0

Synergistic Effect of Lactobacillus Mixtures and Lagerstroemia speciosa Leaf Extract in Reducing Obesity in High-Fat Diet-Fed Mice.

IF 3.6 3区生物学

Biology-Basel Pub Date : 2024-12-13 DOI: 10.3390/biology13121047

Kippeum Lee, Hyeon-Ji Kim, Joo Yun Kim, Jae Jung Shim, Jae Hwan Lee

{"title":"Synergistic Effect of Lactobacillus Mixtures and Lagerstroemia speciosa Leaf Extract in Reducing Obesity in High-Fat Diet-Fed Mice.","authors":"Kippeum Lee, Hyeon-Ji Kim, Joo Yun Kim, Jae Jung Shim, Jae Hwan Lee","doi":"10.3390/biology13121047","DOIUrl":"https://doi.org/10.3390/biology13121047","url":null,"abstract":"In this study, we describe the anti-obesity effects of a novel combination of Lactobacillus mixture (Lactobacillus curvatus HY7601 and Lactobacillus plantarum KY1032) and leaf extract of Lagerstroemia speciosa (L. speciosa) in mice. The administration of the probiotic mixture of HY7601 and KY1032 in combination with the leaf extract of L. speciosa significantly attenuated fat tissue formation and body weight gain in mice fed a high-fat diet. The white adipose fat mass, comprising the inguinal and epididymal fat pads, was most effectively reduced when the probiotic mixture and L. speciosa leaf extract was orally administered to the mice in combination. This combination also reduced the mRNA expression of adipogenic genes (those encoding CCAAT/enhancer-binding protein alpha, peroxisome proliferator-activated receptor gamma, and fatty acid-binding protein 4) in inguinal and epididymal white adipose tissue depots and the liver. Finally, the combination of reduced blood glucose concentrations regulated the insulin resistance of high-fat diet-fed obese mice. These findings provide insight into the mechanisms underlying the effect of this combination and suggest that using Lactobacillus mixture (HY7601 and KY1032) is as safe as microbial monotherapy, but more effective at preventing obesity.","PeriodicalId":48624,"journal":{"name":"Biology-Basel","volume":"13 12","pages":""},"PeriodicalIF":3.6,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11673097/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142957230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of Cold Resistance in Alfalfa Varieties Based on Root Traits and Winter Survival in Horqin Sandy Land.

IF 3.6 3区生物学

Biology-Basel Pub Date : 2024-12-12 DOI: 10.3390/biology13121042

Tao Li, Tiexia Zhu, Zhongguo Liu, Ning Yang, Zhipeng Wang, Tiegang Yang, Kai Gao

{"title":"Evaluation of Cold Resistance in Alfalfa Varieties Based on Root Traits and Winter Survival in Horqin Sandy Land.","authors":"Tao Li, Tiexia Zhu, Zhongguo Liu, Ning Yang, Zhipeng Wang, Tiegang Yang, Kai Gao","doi":"10.3390/biology13121042","DOIUrl":"https://doi.org/10.3390/biology13121042","url":null,"abstract":"The Horqin Sandy Land in China is a key alfalfa production base, challenged by low winter temperatures and large diurnal temperature shifts, affecting alfalfa's winter survival. Alfalfa roots are the primary organs responsible for winter adaptability; consequently, by investigating the changes in the root physiology and nutritional components of alfalfa during the overwintering period, we can enhance our understanding of its mechanisms for cold resistance. Over the course of two years (2022-2023), field trials were conducted on 40 alfalfa varieties selected from both domestic and international sources for their potential cold resistance. This study assessed winter survival rates and analyzed root contents, including soluble sugars, starch, soluble proteins, and the concentrations of carbon (C), nitrogen (N), phosphorus (P) and their stoichiometric ratios. Principal component analysis, subordinate function analysis, and cluster analysis were employed for comprehensive evaluation. Biochemical markers varied significantly across varieties. The C, N, and starch contents in the roots were the main factors determining cold resistance. The varieties were categorized into four groups: Category I included five highly resistant varieties ('Baimu 202', 'WL168HQ', 'Zhongmu No. 1', 'Gongnong No. 1', and 'Legacy'); Category II consisted of six moderately resistant varieties; Category III included twenty-eight slightly resistant varieties; and Category IV contained one non-resistant variety ('3010'). This study recommends the adoption of the five varieties in Category I to enhance alfalfa cultivation in the Horqin region. This research provides valuable theoretical and practical guidance for improving the cultivation of alfalfa in the cold regions of northeastern China, supporting the development of the local livestock industry.","PeriodicalId":48624,"journal":{"name":"Biology-Basel","volume":"13 12","pages":""},"PeriodicalIF":3.6,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11672984/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142957083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0