Pan African Medical Journal最新文献

{"title":"[A case report of paraneoplastic Cushing's syndrome in young adults: a rare entity and real diagnostic challenge].","authors":"Ghizlane Sabbar, Kaoutar Rifai, Fatima Toulali, Hinde Iraqi, Mohamed El Hassan Gharbi","doi":"10.11604/pamj.2025.51.47.46381","DOIUrl":"https://doi.org/10.11604/pamj.2025.51.47.46381","url":null,"abstract":"<p><p>Paraneoplastic Cushing's syndrome is a rare cause of ACTH-dependent Cushing's syndrome, rarely observed in young adults, and often presents a challenge in determining its etiology. We report the case of a 16-year-old female patient presenting with a severe hypercortisolism, for which no underlying cause could initially be identified. Her clinical condition worsened, leading to emergency bilateral adrenalectomy as a life-saving measure. The underlying tumor pathology was diagnosed several months later on the basis of functional imaging. The patient underwent surgical excision, resulting in significant clinical improvement. This case highlights both a rare form of ACTH-dependent Cushing's syndrome and the very young age of onset, demonstrating the difficulty in establishing a precise etiological diagnosis, often requiring advanced imaging techniques.</p>","PeriodicalId":48190,"journal":{"name":"Pan African Medical Journal","volume":"51 ","pages":"47"},"PeriodicalIF":1.0,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12374737/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144974519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical features and natural history of pelvic organ prolapse in South Kivu (Eastern DRC): a cross-sectional study.","authors":"Eloge Ilunga-Mbaya, Dieudonné Sengeyi Mushengezi Amani, Prosper Lukusa Tshilobo, Raha Maroyi, Alex Mutombo Baleka, Mukanire Ntankwinja, Denis Mukwege","doi":"10.11604/pamj.2025.51.48.44340","DOIUrl":"https://doi.org/10.11604/pamj.2025.51.48.44340","url":null,"abstract":"<p><strong>Introduction: </strong>pelvic organ prolapse, a common condition, is a real public health problem in developing countries. Its anamnestic and clinical features may present particularities in these environments. The objective of this study was to assess when women present for treatment and the reasons for delay in seeking care. The authors also describe the clinical particularities of prolapse in the East of the Democratic Republic of Congo.</p><p><strong>Methods: </strong>a cross-sectional study conducted on 217 women with pelvic organ prolapse consulting for the first time. Descriptive statistics and logistic regression were performed to describe clinical features and determinants of delay in seeking care.</p><p><strong>Results: </strong>the mean age was 46.38±14.12. Women under the age of 41 represents a third of the population or 36.4%. Young people (18-30 years old) represented 16.6%. Mechanical symptoms were the main reasons for consultation (63.1%) followed by sexual disorders (21.2%). Half of the population had a lateral cystocele (50.5%) followed by medio-lateral cystocele (32.1%). The average duration of symptoms was 6.67±6.85 years. The farming profession proved to be a determinant of consultation delays with adjusted Odds ratio « aOR » 3.10, 95% Confidence interval « CI », 1.055-3.481 (aOR: 3.10, 95% CI 1.055-3.481; p=0.017) and urban residence a protective factor (aOR: 0.48, 95% CI 0.24-0.97; p=0.04).</p><p><strong>Conclusion: </strong>prolapse affects women of all ages but especially a large proportion of young people in genital activity. The clinic of pelvic organ prolapse in our environment can present particularities and the time is long between the first symptoms occurrence and the decision to consult. Delays in consulting are essentially linked to the profession of farmer and the fact of residing in town is a protective factor for late consultations.</p>","PeriodicalId":48190,"journal":{"name":"Pan African Medical Journal","volume":"51 ","pages":"48"},"PeriodicalIF":1.0,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12374742/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144974478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiology and clinical outcomes of advanced maternal age: a cross-sectional study at Saint-Joseph Hospital and the University Clinics of Kinshasa in the Democratic Republic of Congo.","authors":"Antoine Tshimbundu Kayembe, Anne Kapinga Mutshiaudi, Alex Mutombo Baleka, Andy Mbangama Muela, Rahma Raschid Tozin, Roger Mbungu Mwimba, Dieudonné Sengeyi Mushengezi, Patrick Kahindo Muyayalo","doi":"10.11604/pamj.2025.51.49.47389","DOIUrl":"https://doi.org/10.11604/pamj.2025.51.49.47389","url":null,"abstract":"<p><strong>Introduction: </strong>advanced maternal age is defined as women aged 35 years or older at the estimated date of delivery based on the woman's physiology. Pregnancies at this maternal age are at risk for adverse obstetric outcomes. The objective of this study is to determine the epidemiological and clinical profile of elderly mothers at Saint-Joseph Hospital and the University Clinics of Kinshasa in the Democratic Republic of Congo.</p><p><strong>Methods: </strong>this is a cross-sectional study of a series of records of elderly mothers who were followed and gave birth in the maternity wards of Saint-Joseph Hospital and the University Clinics of Kinshasa from January 1, 2018, to December 31, 2022, using non-probability convenience sampling for case selection. Descriptive analyses were performed in the statistical analyses.</p><p><strong>Results: </strong>the birth rate among advanced mothers was 28.7% with their average age of 38.65 (SD: 2.64) years, housewives, married mothers and those with university education were present respectively in 62.78%, 95% and 49.75% of cases, their average parity was 3.69 (SD: 1.96) deliveries and primiparous mothers were present in 43.2% of cases. The spontaneous abortion´s history was present in 43.2% of cases, scarred uterus history in 29.61% of cases, pregnancy-induced hypertension´s history in 6.1%, and pre-eclampsia´s history in 2.53% of cases. The advanced maternal age was significantly associated with the occurrence of pre-eclampsia (aOR: 3.5, 95% CI: 1.3-9.5, p=0.002), pregnancy-induced hypertension (aOR: 2.3, 95% CI: 1.7-7.8, p=0.012), prematurity (aOR: 2.7, 95% CI: 1.4-5.0, p=0.001), low birth weight (aOR: 2.5, 95% CI: 1.1-63, p=0.002) and admission to neonatal unit (aOR: 2.5, 95% CI: 1.0-6.3, p=0.020).</p><p><strong>Conclusion: </strong>the pregnancy in mothers with advanced maternal age is a real public health problem, primiparas with university education, married women, and housewives with a history of spontaneous abortion and scarred uterus are more affected. Adverse obstetric outcomes include preeclampsia, pregnancy-induced hypertension, prematurity, low birth weight, and admission to the neonatal unit.</p>","PeriodicalId":48190,"journal":{"name":"Pan African Medical Journal","volume":"51 ","pages":"49"},"PeriodicalIF":1.0,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12374739/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144974558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Prevalence and associated factors of hyperuricemia in patients with type 2 diabetes in hospital settings in Dakar, Senegal].","authors":"Ngoné Diaba Diack, Nafy Ndiaye, Ali Hedroj, Arnaud Ndi Manga, Mouhamed Dieng, Djiby Sow, Michel Assane Ndour, Yakham Mouhamed Leye, Demba Diedhiou, Anna Sarr, Maimouna Ndour Mbaye, Abdoulaye Leye","doi":"10.11604/pamj.2025.51.45.47695","DOIUrl":"https://doi.org/10.11604/pamj.2025.51.45.47695","url":null,"abstract":"<p><strong>Introduction: </strong>hyperuricemia increases cardiovascular morbidity and mortality in type 2 diabetes (T2D). The purpose of this study was to determine the prevalence of asymptomatic hyperuricemia in a population with type 2 diabetes and its determinants.</p><p><strong>Methods: </strong>we conducted a cross-sectional study at the Pikine National Hospital Center (CHNP) and the Abass Ndao Hospital Center (Dakar, Senegal). It involved outpatients with type 2 diabetes and without a history or symptoms of gout. Fasting blood samples were taken to measure metabolic parameters (uric acid, HbA1c, lipid profile, and magnesium levels).</p><p><strong>Results: </strong>the study included 90 patients. The mean age was 59,6 ± 8,8 years. There were 24 men and 66 women. The average duration of diabetes was 5 years, with a median HbA1c at inclusion of 7.2%. The prevalence of hyperuricemia was 31.1% (n=28). After multivariate analysis, the factors independently associated with hyperuricemia were male sex (adjusted odds ratio [aOR]: 3.9, 95% CI: 1,3-12,1; p=0,015), and GFR below 60 ml/min (aOR: 7.7, 95% CI: 1,2-48,3; p=0,029). A significant positive correlation was found between triglyceride levels and uric acid levels (r=0.5; p<0.001). Magnesium levels were inversely correlated with uric acid levels (r=-0,3; p=0,051).</p><p><strong>Conclusion: </strong>hyperuricemia is common in patients with type 2 diabetes. Screening is necessary, especially in male patients with impaired renal function and/or hypertriglyceridemia.</p>","PeriodicalId":48190,"journal":{"name":"Pan African Medical Journal","volume":"51 ","pages":"45"},"PeriodicalIF":1.0,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12374736/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144974490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiological characteristics and pathogen profiles of non-<i>Escherichia coli</i> gram-negative urinary tract infections in pregnant women: insights from Makassar, Indonesia.","authors":"Kadri Rusman, Rizalinda Sjahril, Mochammad Hatta, Muhammad Nasrum Massi, Lisa Tenriesa Muslich, Fadhilah Syamsuri, Andi Meutiah Ilhamjaya","doi":"10.11604/pamj.2025.51.46.46208","DOIUrl":"https://doi.org/10.11604/pamj.2025.51.46.46208","url":null,"abstract":"<p><strong>Introduction: </strong>urinary tract infections (UTIs) during pregnancy pose significant health risks for both mother and fetus. While Escherichia coli is the most common causative agent, non-Escherichia coli gram-negative bacteria also contribute to UTIs, with their specific prevalence and characteristics in pregnant women needing further elucidation, particularly in local contexts. This study aimed to identify gram-negative non-Escherichia coli bacteria causing UTIs in pregnant women and to determine their epidemiological characteristics in Makassar, Indonesia.</p><p><strong>Methods: </strong>a cross-sectional study was conducted at the Clinical Microbiology Laboratory of Hasanuddin University Hospital, Makassar, from July to August 2024. The study utilized 38 non-Escherichia coli bacterial isolates from urine cultures of pregnant women diagnosed with UTIs at various community health centers. After re-culturing on MacConkey Agar, bacterial identification was performed using the API 20e system. Epidemiological data were collected from medical records and questionnaires.</p><p><strong>Results: </strong>among 38 non-Escherichia coli isolates, Enterobacter cloacae was most prevalent (34.2%), followed by Klebsiella pneumoniae spp. Pneumoniae (23.7%). Most isolates (76.3%) were lactose fermenters. Epidemiologically, the 25-34 age group dominated (71.0%), with the highest UTI incidence in first pregnancies (47.4%) and the second trimester (44.7%). Significantly, 97.4% of pregnant women with UTI symptoms did not seek treatment.</p><p><strong>Conclusion: </strong>Enterobacter cloacae is the most common non-Escherichia coli gram-negative UTI bacterium in this Makassar cohort. Key epidemiological characteristics were elucidated, revealing a substantial proportion of women not seeking treatment for UTI symptoms. These findings underscore the importance of local surveillance and targeted health education interventions for pregnant women regarding UTI management.</p>","PeriodicalId":48190,"journal":{"name":"Pan African Medical Journal","volume":"51 ","pages":"46"},"PeriodicalIF":1.0,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12374735/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144974568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Parental acceptance of human papillomavirus vaccine for female adolescents in Abia State, southeastern Nigeria: a pre-implementation study.","authors":"Chidinma Ihuoma Amuzie, Amos Paul Bassi, Eliza Fishman, Dessie Mekonnen, Quail Rogers-Bloch, Kelli Cappelier, Scott LaMontagne, Kalu Ulu Kalu, Michael Izuka, Sola Thomas Sunday","doi":"10.11604/pamj.2025.51.44.43317","DOIUrl":"https://doi.org/10.11604/pamj.2025.51.44.43317","url":null,"abstract":"<p><strong>Introduction: </strong>cervical cancer is the second most common cancer amongst women in Nigeria, with an incidence rate of 26.2 per 100,000 and mortality rate of 14.3 per 1000 adult women. Vaccination is the primary prevention if initiated prior to Human Papillomavirus (HPV) infection. However, vaccine hesitancy remains a threat to the uptake of the HPV vaccine. This study identified the pattern and predictors of parental acceptance of HPV vaccines for their female adolescents in Abia State, Nigeria prior to state level introduction.</p><p><strong>Methods: </strong>we conducted a community-based cross-sectional study between August and September 2023 among parents of female adolescents residing in Abia State. A multistage sampling technique was used to select the study respondents. An interviewer-based, semi-structured questionnaire was administered to the respondents. Analysis was done using IBM SPSS version 26. Univariate analysis was used to present the socio-demographic characteristics of the respondents in frequencies and proportions. The association between parental acceptance and the independent variables was assessed using the chi-square test. Logistic regression was used to identify the independent predictors of parental acceptance of HPV vaccination. The level of significance was 5%.</p><p><strong>Results: </strong>a total of 1,016 respondents participated in this survey, with a mean age of 42.2 ± 10.5 years. The prevalence of parental HPV vaccine acceptance was 63.0% (95% CI: 59.8 - 66.0). The major sources of information on the HPV vaccine were the healthcare workers (43.0%) and social media (37.8%). Among respondents who would accept the HPV vaccine for their female adolescents, the commonest reason was for the prevention of HPV transmission (58.3%). Most of the respondents who declined willingness reported lack of information (63.9%), followed by fear of adverse effects (32.9%) as the triggers for non-acceptance of the vaccine. The most preferable source of HPV vaccine recommendation mentioned by the respondents were healthcare workers (92.7%). Female (aOR=1.44, 95% CI: 1.02 - 2.03), good knowledge of HPV infection (aOR=2.87, 95% CI: 1.82 - 4.53) and good knowledge of HPV vaccine (aOR=18.52, 95% CI: 10.52 - 32.61) were the predictors of HPV vaccine acceptance.</p><p><strong>Conclusion: </strong>prior to the introduction of HPV vaccine into the routine immunization of Abia State, Nigeria, most parents surveyed indicated that they would accept HPV vaccine for their female adolescents. Sex, knowledge of HPV infection and HPV vaccine were the independent predictors of parental acceptance of HPV vaccine. We recommend the raising of awareness campaign on HPV vaccine benefits and safety, prioritizing healthcare workers and the social media as the major channels of communication to support HPV vaccination.</p>","PeriodicalId":48190,"journal":{"name":"Pan African Medical Journal","volume":"51 ","pages":"44"},"PeriodicalIF":1.0,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12374744/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144974549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic and therapeutic challenges of a heparin-induced thrombocytopenia in HIV immunodeficiency: in regards to a pediatric case (a case report).","authors":"Mouna Zouine, Yousra El Boussadani, Abdallah Oulmaati","doi":"10.11604/pamj.2025.51.43.46466","DOIUrl":"https://doi.org/10.11604/pamj.2025.51.43.46466","url":null,"abstract":"<p><p>We are dealing with a female infant case who had a cerebral venous thrombosis, revealing a secondary immunodeficiency, owing to a human immunodeficiency virus infection. After anticoagulant treatment with low-molecular-weight heparin (LMWH), it came to light that she had a severe thrombocytopenia, suggesting a thrombocytopenia induced by an auto-immune origin of heparin. Within a developing country in which means of confirmation are not always available, it was difficult to identify whether severe thrombocytopenia was owing to HIV infection, sepsis, or heparin. The therapeutic decision was therefore difficult, because stopping anticoagulation can lead to a cerebral thrombosis extension.</p>","PeriodicalId":48190,"journal":{"name":"Pan African Medical Journal","volume":"51 ","pages":"43"},"PeriodicalIF":1.0,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12374743/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144974628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unveiling dengue fever prevention and control strategy in Ethiopia: a policy landscape analysis.","authors":"Chalachew Sisay, Netsanet Worku, Tadesse Awoke, Kassahun Alemu","doi":"10.11604/pamj.2025.51.42.47457","DOIUrl":"https://doi.org/10.11604/pamj.2025.51.42.47457","url":null,"abstract":"<p><strong>Introduction: </strong>dengue fever is an emerging mosquito-borne viral disease in Ethiopia. To sustainably address its incidence and impact, a strong policy framework is essential for enhancing prevention and control efforts. This study aimed to explore existing operational policies and identify the facilitators and barriers to implementing tailored, country-specific strategies.</p><p><strong>Methods: </strong>the study employed a mixed-methods design. A desk review analysis, utilizing the policy triangle framework, examined existing operational policy documents, analyzing their content, context, actors, and processes. Additionally, eight key informant interviews were conducted with stakeholders, leading to the development of a thematic analysis based on the study objectives.</p><p><strong>Results: </strong>six dengue fever prevention and control policy documents were identified. Two from the Ministry of Health and four from the Ethiopian Public Health Institute lacked details regarding target populations, geographic areas, risk levels, and the focus of interventions across different contexts. A qualitative review revealed that the lack of tailored, country-specific intervention strategies, the absence of dedicated programs, and insufficient budget allocation to dengue fever prevention and control. Furthermore, collaboration among ministries and health stakeholders was poor, and the application of operational research was limited.</p><p><strong>Conclusion: </strong>the identified gaps emphasize the urgent need for a comprehensive strategy to address dengue prevention and control. This involves developing tailored, country-specific intervention strategies and establishing a dedicated dengue program with sufficient resources. Robust early warning surveillance systems, coupled with strengthened intra- and inter-sectoral collaboration, are crucial for coordinated dengue fever control. Implementing cost-effective, locally adapted integrated vector management strategies, guided by a one health approach.</p>","PeriodicalId":48190,"journal":{"name":"Pan African Medical Journal","volume":"51 ","pages":"42"},"PeriodicalIF":1.0,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12374738/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144974611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The prevalence and severity of late postnatal anaemia amongst women at the Buea and Limbe Regional Hospitals in Cameroon.","authors":"Nancy Labu Nji, Nicholas Tendongfor, Roussel Ngetsche Ambebe, Julie Nchung Ashu, Magouanet Sandrine Tchio, Jules Clement Assob Nguedia, Gregory Edie Halle-Ekane","doi":"10.11604/pamj.2025.51.41.40494","DOIUrl":"https://doi.org/10.11604/pamj.2025.51.41.40494","url":null,"abstract":"<p><strong>Introduction: </strong>late postnatal anaemia is not routinely investigated in lower-middle and low-income countries. Hence, it remains undiagnosed and untreated. There are quality of life, morbidity, and mortality implications of anaemia in this period. The objective of this study was to determine the prevalence, severity, and factors predisposing to late postnatal anaemia amongst women in the Buea Regional Hospital (BRH) and the Limbe Regional Hospital (LRH), Cameroon.</p><p><strong>Methods: </strong>a cross-sectional study amongst 355 women between the 6^th to 27^th week postpartum was conducted. Data collection using a structured questionnaire and capillary hemoglobin (Hb) was measured with the Sejoy® Hemoglobinometer. Late postnatal anaemia was defined by a Hb < 12g/dl between the 6^th to 27^th week postpartum. The prevalence of anaemia was calculated as the proportion of women with a haemoglobin level less than 12g/dl in the LPNP concerning the total population of women studied. The severity of anaemia was categorized into mild, moderate, and severe. The relationship between late postnatal anaemia (LPNA) and predictor variables was analyzed by the binary logistic regression method for odds ratios and p-values. Data analysis using SPSS version 23 with statistical significance set at a p-value < 0.05 at a 95% confidence interval.</p><p><strong>Results: </strong>there were 109 women out of the 355 participants with anemia, giving a prevalence of 30.7%. A majority of whom had mild and moderate anemia, that is 61 (56%) and 46 (43.1%) respectively, with only 1 (0.9%) participant with severe anemia. Level of education (p= 0.030), trimester of commencing antenatal care consultations (p=0.001), prenatal anemia (p=0.003), the baby??s birth weight (p= 0.047), and mucocutaneous pallor (p<0.001) were significantly and independently associated with late postnatal anemia.</p><p><strong>Conclusion: </strong>late postnatal anaemia is relatively common in this study setting, demonstrating a prevalence of 3 in 10 women affected. However, most cases are with mild to moderate anaemia. Determinants found were a low level of education, late commencement of antenatal care, prenatal anaemia, and mothers with low-birth-weight babies, plus mucocutaneous palor.</p>","PeriodicalId":48190,"journal":{"name":"Pan African Medical Journal","volume":"51 ","pages":"41"},"PeriodicalIF":1.0,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12374741/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144974623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Takotsubo cardiomyopathy due to a pheochromocytoma: a case report.","authors":"Fatima Toulali, Afrah El Kaissi, Nada Ait Kassi, Hiba Kouira, Kaoutar Rifai, Hinde Iraqi, Mohammed El Hassan Gharbi","doi":"10.11604/pamj.2025.51.39.47439","DOIUrl":"10.11604/pamj.2025.51.39.47439","url":null,"abstract":"<p><p>Takotsubo cardiomyopathy is typically triggered by severe adrenergic surges secondary to various stress factors. In rare cases, excessive catecholamine secretion due to a pheochromocytoma may be the cause. It is typically manifested by dyskinesia of the apex of the left ventricle. In this case report, we describe an atypical case of takotsubo cardiomyopathy, characterized by hypokinesia of the apical and mid-segments of the inferior wall of the left ventricle, which led to the discovery of an underlying pheochromocytoma. Although this association is rare, it is crucial to consider it, especially in atypical forms, as once the tumor is resected, the phenomenon becomes reversible.</p>","PeriodicalId":48190,"journal":{"name":"Pan African Medical Journal","volume":"51 ","pages":"39"},"PeriodicalIF":1.0,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12329457/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144800643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}