World Journal of Orthopedics最新文献

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Total hip arthroplasty following the failure of intertrochanteric nailing: First implant or salvage surgery? 转子间钉钉失败后全髋关节置换术:首次植入还是保留手术?
IF 1.9
World Journal of Orthopedics Pub Date : 2023-10-18 DOI: 10.5312/wjo.v14.i10.763
Giuseppe Solarino, Davide Bizzoca, Pasquale Dramisino, Giovanni Vicenti, Lorenzo Moretti, Biagio Moretti, Andrea Piazzolla
{"title":"Total hip arthroplasty following the failure of intertrochanteric nailing: First implant or salvage surgery?","authors":"Giuseppe Solarino, Davide Bizzoca, Pasquale Dramisino, Giovanni Vicenti, Lorenzo Moretti, Biagio Moretti, Andrea Piazzolla","doi":"10.5312/wjo.v14.i10.763","DOIUrl":"https://doi.org/10.5312/wjo.v14.i10.763","url":null,"abstract":"<p><strong>Background: </strong>Proximal femur fractures, including both intracapsular (femoral neck fractures) and extracapsular fractures (intertrochanteric femoral fractures, IFFs), affect around 1.5 million people per year worldwide. Mechanical failures of intertrochanteric nailing in IFFs could be managed with revision total hip arthroplasty (THA).</p><p><strong>Aim: </strong>To describe the surgical complexity and the procedure-related complication rates in patients with trochanteric nailing failure and treated with THA.</p><p><strong>Methods: </strong>Patients referred to our level I trauma center between April 2012 and July 2018 with failed cephalomedullary nailing following trochanteric fractures were retrospectively recruited. All patients underwent a salvage surgical procedure, <i>i.e.</i>, cephalomedullary nail removal and conversion to THA. The same surgical and anesthesiology team performed the surgical procedures under spinal anesthesia. All patients underwent clinical and radiographic follow-ups for at least 24 mo. Complications and re-operations were recorded.</p><p><strong>Results: </strong>Seventy-four patients met the inclusion criteria (male: 29; female: 45; mean age: 73.8-years-old; range: 65-89) and were included in the current study. The average operative time was 117 min (76-192 min). The average blood loss was 585 mL (430-1720 mL). Among the 74 patients, 43 (58.1%) required transfusion of three or more blood units. Two patients died within the 4<sup>th</sup> d after surgery because of pulmonary embolism, and 1 patient died 9 mo after surgery due to ischemic myocardial infarction. The complication rate in the 71 patients who completed the minimum 24-mo follow-up was 22.5%. In 3 cases out of 71 (4.2%) periprosthetic acetabular fracture was observed during the follow-up. One of these periacetabular fractures occurred intraoperatively. An intraoperative periprosthetic femur fracture was observed in 5 patients out of 71 (7.0%). Four of these patients needed a re-operation to fix the fracture with plates and cerclages; in one of these patients, femoral stem revision was also necessary. In 4 patients out of 71 (5.6%), an early THA dislocation was observed, whereas in 1 case (1.4%) a late THA dislocation was observed. Three patients out of 71 (4.2%) developed a periprosthetic joint infection during the study follow-up.</p><p><strong>Conclusion: </strong>The present study demonstrated that salvage options for IFF fixation failure are complex procedures with a relevant intraoperative and postoperative complication rate.</p>","PeriodicalId":47843,"journal":{"name":"World Journal of Orthopedics","volume":"14 10","pages":"763-770"},"PeriodicalIF":1.9,"publicationDate":"2023-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10642404/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134650218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Late brachial plexopathy after a mid-shaft clavicle fracture: A case report. 锁骨中轴骨折后晚期臂丛病1例。
IF 1.9
World Journal of Orthopedics Pub Date : 2023-10-18 DOI: 10.5312/wjo.v14.i10.776
Mohammad M Alzahrani
{"title":"Late brachial plexopathy after a mid-shaft clavicle fracture: A case report.","authors":"Mohammad M Alzahrani","doi":"10.5312/wjo.v14.i10.776","DOIUrl":"https://doi.org/10.5312/wjo.v14.i10.776","url":null,"abstract":"<p><strong>Background: </strong>Clavicle fractures can rarely be associated with brachial plexus injury. These are commonly caused by tractional injury at the time of trauma, but unfrequently can be caused by compression of the brachial plexus from excessive callus or granulation tissue formation.</p><p><strong>Case summary: </strong>We report a rare case of an adult male who sustained a mid-shaft clavicle fracture and had a late presentation of brachial plexus palsy due to compression from excessive callus formation.</p><p><strong>Conclusion: </strong>We reported a case of a rare occurrence of delayed brachial plexus palsy due to compression from excessive callus formation in a midshaft clavicle fracture. Early diagnosis and surgical decompression of the brachial plexus is critical, as when managed efficiently, a full recovery of the brachial plexus palsy can be expected in these patients.</p>","PeriodicalId":47843,"journal":{"name":"World Journal of Orthopedics","volume":"14 10","pages":"776-783"},"PeriodicalIF":1.9,"publicationDate":"2023-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10642401/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134650167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vancomycin flushing syndrome in orthopaedic practice: A case report. 骨科实践中万古霉素潮红综合征1例报告。
IF 1.9
World Journal of Orthopedics Pub Date : 2023-10-18 DOI: 10.5312/wjo.v14.i10.771
Fawaz M Al-Anii, Mir Sadat-Ali, Khalid Waleed Al-Tabash, Ahmad I AlMulhim, Sulaiman A AlMousa, Abdulaziz M AlHawas
{"title":"Vancomycin flushing syndrome in orthopaedic practice: A case report.","authors":"Fawaz M Al-Anii, Mir Sadat-Ali, Khalid Waleed Al-Tabash, Ahmad I AlMulhim, Sulaiman A AlMousa, Abdulaziz M AlHawas","doi":"10.5312/wjo.v14.i10.771","DOIUrl":"https://doi.org/10.5312/wjo.v14.i10.771","url":null,"abstract":"<p><strong>Background: </strong>Vancomycin flushing syndrome (VFS), also known as red man syndrome, is an allergic reaction to vancomycin. It typically presents as a rash on the face, neck, and upper torso after intravenous administration of vancomycin. VFS is blamed on rapid intravenous infusion of vancomycin during management and rarely happens after local use. A review of the literature showed that in the last 23 years, 4 such cases have been reported. Here, we add another case of VFS developed after slow local absorption of vancomycin in cement beads.</p><p><strong>Case summary: </strong>A 44-year-old male with a known case of hypertension, no history of allergies to medications, and a history of chronic osteomyelitis of the right tibia with discharging sinus over the anterolateral aspect of the leg. The pus culture grew <i>Staphylococcus aureus</i>, which was sensitive to clindamycin and vancomycin. The patient underwent irrigation and debridement with the placement of vancomycin cement beads made from 4 g of vancomycin powder and 40 g of polymethyl methacrylate. Three hours postoperatively, the patient developed a pruritic, erythematous, macular rash predominantly on his face, neck, chest, and lower extremities and to a lesser extent his upper extremities. A diagnosis of VFS was made and was successfully treated with cetirizine (10 mg, oral) and methylprednisolone sodium succinate (125 mg, intravenous). The patient continued to have itching with a facial rash for 12 h with gradual improvement. A decision was made to not remove the beads as the patient continued to improve. Gradually, the rash disappeared after 96 h with no further sequela.</p><p><strong>Conclusion: </strong>VFS can occur not only after rapid intravenous injection of vancomycin but also with local release, as in our case. As orthopaedic surgeons routinely use vancomycin with polymethyl methacrylate in chronic osteomyelitis and revision arthroplasty, they should be aware of such a complication occurring.</p>","PeriodicalId":47843,"journal":{"name":"World Journal of Orthopedics","volume":"14 10","pages":"771-775"},"PeriodicalIF":1.9,"publicationDate":"2023-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10642402/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134650220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Catania flatfoot score: A diagnostic-therapeutic evaluation tool in children. 卡塔尼亚平足评分:儿童诊断治疗评估工具。
IF 1.9
World Journal of Orthopedics Pub Date : 2023-10-18 DOI: 10.5312/wjo.v14.i10.755
Andrea Vescio, Gianluca Testa, Alessia Caldaci, Marco Sapienza, Vito Pavone
{"title":"Catania flatfoot score: A diagnostic-therapeutic evaluation tool in children.","authors":"Andrea Vescio, Gianluca Testa, Alessia Caldaci, Marco Sapienza, Vito Pavone","doi":"10.5312/wjo.v14.i10.755","DOIUrl":"https://doi.org/10.5312/wjo.v14.i10.755","url":null,"abstract":"<p><strong>Background: </strong>Flexible flatfoot (FFF) is a very common condition in children, but no evidence-based guidelines or assessment tools exist. Yet, surgical indication is left to the surgeon's experience and preferences.</p><p><strong>Aim: </strong>To develop a functional clinical score for FFF [Catania flatfoot (CTF) score] and a measure of internal consistency; to evaluate inter-observer and intra-observer reliability of the CTF Score; to provide a strong tool for proper FFF surgical indication.</p><p><strong>Methods: </strong>CTF is a medically compiled score of four main domains for a total of twelve items: Patient features, Pain, Clinical Parameters, and Functionality. Each item refers to a specific rate. Five experienced observers answered 10 case reports according to the CTF. To assess inter- and intra-observer reliability of the CTF score, the intra-class correlation coefficients' (ICCs) statistics test was performed, as well as to gauge the correlation between the CTF score and the surgical or conservative treatment indication. Values of 75% were chosen as the score cut-off for surgical indication. Sensitivity, specificity, positive likelihood ratio (PLHR), negative likelihood ratio (NLHR), positive predictive value (PPV), and negative predictive value (NPV).</p><p><strong>Results: </strong>Overall interobserver reliability ICC was 0.87 [95% confidence interval (CI): 0.846-0.892; <i>P</i> < 0.001]. Overall intra-observer reliability ICC was 0.883 (95%CI: 0.854-0.909; <i>P</i> < 0.001). A direct correlation between the CTF score and surgical treatment indication [Pearson correlation coefficient = 0.94 (<i>P</i> < 0.001)] was found. According to the 75% cut-off, the sensitivity was 100% (95%CI: 83.43%-100%), specificity was 85.71% (95%CI: 75.29%-92.93%), PLHR was 7 (95%CI: 3.94-12.43), NLHR was 0 (95%CI: 0-0), PPV was 75% (95%CI: 62.83%-84.19%) and NPV was 100% (95%CI: 100%-100%).</p><p><strong>Conclusion: </strong>CTF represents a useful tool for orthopedic surgeons in the FFF evaluation. The CTF score is a quality questionnaire to reproduce suitable clinical research, survey studies, and clinical practice. Moreover, the 75% cut-off is an important threshold for surgical indication and helps in the decision-making process.</p>","PeriodicalId":47843,"journal":{"name":"World Journal of Orthopedics","volume":"14 10","pages":"755-762"},"PeriodicalIF":1.9,"publicationDate":"2023-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10642399/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134650166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Machine learning applications for the prediction of extended length of stay in geriatric hip fracture patients. 机器学习在老年髋部骨折患者延长住院时间预测中的应用。
IF 1.9
World Journal of Orthopedics Pub Date : 2023-10-18 DOI: 10.5312/wjo.v14.i10.741
Chu-Wei Tian, Xiang-Xu Chen, Liu Shi, Huan-Yi Zhu, Guang-Chun Dai, Hui Chen, Yun-Feng Rui
{"title":"Machine learning applications for the prediction of extended length of stay in geriatric hip fracture patients.","authors":"Chu-Wei Tian, Xiang-Xu Chen, Liu Shi, Huan-Yi Zhu, Guang-Chun Dai, Hui Chen, Yun-Feng Rui","doi":"10.5312/wjo.v14.i10.741","DOIUrl":"https://doi.org/10.5312/wjo.v14.i10.741","url":null,"abstract":"<p><strong>Background: </strong>Geriatric hip fractures are one of the most common fractures in elderly individuals, and prolonged hospital stays increase the risk of death and complications. Machine learning (ML) has become prevalent in clinical data processing and predictive models. This study aims to develop ML models for predicting extended length of stay (eLOS) among geriatric patients with hip fractures and to identify the associated risk factors.</p><p><strong>Aim: </strong>To develop ML models for predicting the eLOS among geriatric patients with hip fractures, identify associated risk factors, and compare the performance of each model.</p><p><strong>Methods: </strong>A retrospective study was conducted at a single orthopaedic trauma centre, enrolling all patients who underwent hip fracture surgery between January 2018 and December 2022. The study collected various patient characteristics, encompassing demographic data, general health status, injury-related data, laboratory examinations, surgery-related data, and length of stay. Features that exhibited significant differences in univariate analysis were integrated into the ML model establishment and subsequently cross-verified. The study compared the performance of the ML models and determined the risk factors for eLOS.</p><p><strong>Results: </strong>The study included 763 patients, with 380 experiencing eLOS. Among the models, the decision tree, random forest, and extreme Gradient Boosting models demonstrated the most robust performance. Notably, the artificial neural network model also exhibited impressive results. After cross-validation, the support vector machine and logistic regression models demonstrated superior performance. Predictors for eLOS included delayed surgery, D-dimer level, American Society of Anaesthesiologists (ASA) classification, type of surgery, and sex.</p><p><strong>Conclusion: </strong>ML proved to be highly accurate in predicting the eLOS for geriatric patients with hip fractures. The identified key risk factors were delayed surgery, D-dimer level, ASA classification, type of surgery, and sex. This valuable information can aid clinicians in allocating resources more efficiently to meet patient demand effectively.</p>","PeriodicalId":47843,"journal":{"name":"World Journal of Orthopedics","volume":"14 10","pages":"741-754"},"PeriodicalIF":1.9,"publicationDate":"2023-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10642403/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134650168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Relationships among body weight, lipids and bone mass in elderly individuals with fractures: A case-control study. 老年骨折患者体重、血脂和骨量之间的关系:一项病例对照研究。
IF 1.9
World Journal of Orthopedics Pub Date : 2023-09-18 DOI: 10.5312/wjo.v14.i9.720
Xiang-Xu Chen, Chu-Wei Tian, Li-Yong Bai, Ya-Kuan Zhao, Cheng Zhang, Liu Shi, Yuan-Wei Zhang, Wen-Jun Xie, Huan-Yi Zhu, Hui Chen, Yun-Feng Rui
{"title":"Relationships among body weight, lipids and bone mass in elderly individuals with fractures: A case-control study.","authors":"Xiang-Xu Chen,&nbsp;Chu-Wei Tian,&nbsp;Li-Yong Bai,&nbsp;Ya-Kuan Zhao,&nbsp;Cheng Zhang,&nbsp;Liu Shi,&nbsp;Yuan-Wei Zhang,&nbsp;Wen-Jun Xie,&nbsp;Huan-Yi Zhu,&nbsp;Hui Chen,&nbsp;Yun-Feng Rui","doi":"10.5312/wjo.v14.i9.720","DOIUrl":"https://doi.org/10.5312/wjo.v14.i9.720","url":null,"abstract":"<p><strong>Background: </strong>The prevalence of osteoporosis and low bone mass is steadily rising each year. Low body weight is commonly linked to diminished bone mass and serves as a robust predictor of osteoporosis. Nonetheless, the connection between body mass index (BMI), bone mineral density, and lipid profiles among the elderly remains elusive.</p><p><strong>Aim: </strong>To examine the association between BMI and bone mass, explore the correlation between lipid profiles and bone mass, and delve into the interplay between lipid metabolism and bone health.</p><p><strong>Methods: </strong>The study included 520 patients aged ≥ 65 years (178 men and 342 women). Age, sex, weight, and height were recorded. Femoral neck bone mineral density and T scores were determined using a dual-energy X-ray absorptiometry scanner. Blood calcium (Ca), phosphorus (P), albumin (ALB), alkaline phosphatase (ALP), aspartate aminotransferase, alanine aminotransferase, triglyceride (TG), total cholesterol (TC), high-density lipoprotein (HDL) and low-density lipoprotein (LDL) levels were measured. Patients were classified by sex (male and female), age (65-79 years and ≥ 80 years), and T score (normal bone mineral density, osteopenia and osteoporosis).</p><p><strong>Results: </strong>Age, sex, BMI, and ALP and TG levels were independent risk factors for osteoporosis. For the 65-79- and ≥ 80-year-old groups, females presented lower T scores than males. Ca, P, ALB, ALP, TC, HDL and LDL levels were significantly different between men and women in the 65-79-year-old group. In addition, BMI and TG levels were significantly decreased in osteoporotic patients compared with patients with normal bone mass. TC levels declined in 65- to 79-year-old male and female osteoporosis patients. In the group of women aged ≥ 80 years, osteoporotic patients showed significantly increased ALP levels. Furthermore, we found positive correlations between BMI and TG levels in the male and female patient groups. However, we found no significant differences in ALB, Ca, P, HDL and LDL levels in osteoporotic patients compared to patients with normal bone mass.</p><p><strong>Conclusion: </strong>Osteoporotic patients showed significantly decreased BMI and TG levels compared with those with normal bone mass. BMI showed positive correlations with TG levels in male and female patients. These results indicate correlations between BMI and bone mass and between lipid profiles and bone mass.</p>","PeriodicalId":47843,"journal":{"name":"World Journal of Orthopedics","volume":"14 9","pages":"720-732"},"PeriodicalIF":1.9,"publicationDate":"2023-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/62/50/WJO-14-720.PMC10514712.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41180252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epidemiology of shoulder dislocations presenting to United States emergency departments: An updated ten-year study. 美国急诊科肩部脱臼的流行病学:一项更新的十年研究。
IF 1.9
World Journal of Orthopedics Pub Date : 2023-09-18 DOI: 10.5312/wjo.v14.i9.690
Cole M Patrick, Josiah Snowden, Michael D Eckhoff, Clare K Green, John P Scanaliato, John C Dunn, Nata Parnes
{"title":"Epidemiology of shoulder dislocations presenting to United States emergency departments: An updated ten-year study.","authors":"Cole M Patrick,&nbsp;Josiah Snowden,&nbsp;Michael D Eckhoff,&nbsp;Clare K Green,&nbsp;John P Scanaliato,&nbsp;John C Dunn,&nbsp;Nata Parnes","doi":"10.5312/wjo.v14.i9.690","DOIUrl":"https://doi.org/10.5312/wjo.v14.i9.690","url":null,"abstract":"<p><strong>Background: </strong>Glenohumeral dislocation is a common injury that may predispose patients to chronic pain and instability. However, there is a paucity of current data available regarding the epidemiological trends of this injury.</p><p><strong>Aim: </strong>To provide an updated, comparative assessment of the epidemiology of shoulder dislocations presenting to emergency departments in the United States. We also sought to analyze patient demographic risk factors and consumer products associated with dislocation events.</p><p><strong>Methods: </strong>Data were obtained from the national electronic injury surveillance system database for glenohumeral dislocations between 2012 and 2021. Incidence, age, sex, and injury characteristics were analyzed using weighted population statistics as well as incidence rates and 95% confidence intervals (CI).</p><p><strong>Results: </strong>In total, an estimated 773039 shoulder dislocations (CI: 640598-905481) presented to emergency rooms across the United States during the study period. The annual incidence rate was 23.96 per 100000 persons and the average patient age at the time of injury was 37.1 years. Significantly more male patients sustained dislocations than female patients (537189, 69.5%, <i>vs</i> 235834, 30.5%, <i>P</i> < 0.001). With regard to associated consumer products, sports and recreation equipment were involved in the highest proportion of incidents (44.31%), followed by home structures and construction materials (21.22%), and home furnishings, fixtures, and accessories (21.21%). Regarding product sub-groups, stairs, ramps, landings, floors was cited in the greatest number of cases (131745).</p><p><strong>Conclusion: </strong>The national annual incidence rate of glenohumeral dislocations throughout the study period was approximately 23.92 per 100000 persons. Male adolescents sustained the highest proportion of dislocations, with a peak incidence in age group 15-20 years, predominantly secondary to participation in sporting and recreational activities. Conversely, women experienced a relatively consistent incidence of dislocation throughout their lifespan. After age 63, the incidence rate of dislocations in females was found to surpass that observed in males.</p>","PeriodicalId":47843,"journal":{"name":"World Journal of Orthopedics","volume":"14 9","pages":"690-697"},"PeriodicalIF":1.9,"publicationDate":"2023-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/93/64/WJO-14-690.PMC10514709.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41165823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Silver nanoparticle technology in orthopaedic infections. 银纳米粒子技术在骨科感染中的应用。
IF 1.9
World Journal of Orthopedics Pub Date : 2023-09-18 DOI: 10.5312/wjo.v14.i9.662
Madhan Jeyaraman, Naveen Jeyaraman, Arulkumar Nallakumarasamy, Karthikeyan P Iyengar, Vijay Kumar Jain, Anish G Potty, Ashim Gupta
{"title":"Silver nanoparticle technology in orthopaedic infections.","authors":"Madhan Jeyaraman,&nbsp;Naveen Jeyaraman,&nbsp;Arulkumar Nallakumarasamy,&nbsp;Karthikeyan P Iyengar,&nbsp;Vijay Kumar Jain,&nbsp;Anish G Potty,&nbsp;Ashim Gupta","doi":"10.5312/wjo.v14.i9.662","DOIUrl":"https://doi.org/10.5312/wjo.v14.i9.662","url":null,"abstract":"<p><p>The irrational and prolonged use of antibiotics in orthopaedic infections poses a major threat to the development of antimicrobial resistance. To combat antimicrobial resistance, researchers have implemented various novel and innovative modalities to curb infections. Nanotechnology involves doping ions/metals onto the scaffolds to reach the target site to eradicate the infective foci. In this connotation, we reviewed silver nanoparticle technology in terms of mechanism of action, clinical applications, toxicity, and regulatory guidelines to treat orthopaedic infections.</p>","PeriodicalId":47843,"journal":{"name":"World Journal of Orthopedics","volume":"14 9","pages":"662-668"},"PeriodicalIF":1.9,"publicationDate":"2023-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c9/94/WJO-14-662.PMC10514710.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41178825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Use of orthotics with orthotic sandals versus the sole use of orthotics for plantar fasciitis: Randomised controlled trial. 矫形器与矫形器凉鞋的使用与足趾筋膜炎矫形器的单独使用:随机对照试验。
IF 1.9
World Journal of Orthopedics Pub Date : 2023-09-18 DOI: 10.5312/wjo.v14.i9.707
Portia Amoako-Tawiah, Holly Love, Jaida Chacko Madathilethu, Jessica LaCourse, Alice E Fortune, Jonathan M G Sims, George Ampat
{"title":"Use of orthotics with orthotic sandals versus the sole use of orthotics for plantar fasciitis: Randomised controlled trial.","authors":"Portia Amoako-Tawiah,&nbsp;Holly Love,&nbsp;Jaida Chacko Madathilethu,&nbsp;Jessica LaCourse,&nbsp;Alice E Fortune,&nbsp;Jonathan M G Sims,&nbsp;George Ampat","doi":"10.5312/wjo.v14.i9.707","DOIUrl":"https://doi.org/10.5312/wjo.v14.i9.707","url":null,"abstract":"BACKGROUND Plantar fasciitis (PF) affects around 10% of the population. Prefabricated orthotics with arch support has been shown to provide symptom relief in PF by decreasing the repetitive stress sustained by the plantar fascia. However, prefabricated orthotics are only effective when shoes are worn, meaning the foot may be left unsupported when it is impractical to wear shoes. Using orthotic sandals in conjunction with prefabricated orthotics may increase PF symptom relief, as they can be worn inside the home, extending the period in which the foot is supported. AIM To compare the combined use of prefabricated orthotics and orthotic sandals vs the sole use of prefabricated orthotics in the treatment of PF. METHODS 98 participants with PF were randomised into two groups. The intervention group received the Aetrex L420 Compete orthotics and the Aetrex L3000 Maui Flips (orthotic sandals), whilst the control group received the Aetrex L420 Compete orthotics only. Foot pain was assessed both by the numerical rating scale (NRS) and the pain sub-scale of the foot health status questionnaire (FHSQ). Foot functionality was measured using the function sub-scale of the FHSQ. Symptom change was measured using the global rating of change scale (GROC). RESULTS Foot pain scores measured both by NRS and FHSQ pain sub-scale showed statistically significant reductions in foot pain in both groups (P < 0.05) at six months. Both groups also reported statistically significant improvements (P < 0.05) in function as measured by the FHSQ function subscale and improvement of symptoms as measured by the GROC scale. Between-group analysis showed that the intervention group with the combined use of orthotics and orthotic sandals scored better on all four outcome measures as compared to the control group with the sole use of orthotics. However, the between-group analysis only reached statistical significance on the NRS pain score (P < 0.05). CONCLUSION Combined use of prefabricated orthotics and orthotic sandals provides a greater decrease in foot pain and improvement in foot function in PF compared to using prefabricated orthotics alone.","PeriodicalId":47843,"journal":{"name":"World Journal of Orthopedics","volume":"14 9","pages":"707-719"},"PeriodicalIF":1.9,"publicationDate":"2023-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/aa/1f/WJO-14-707.PMC10514714.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41171641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative study in vivo of the osseointegration of 3D-printed and plasma-coated titanium implants. 3D打印和等离子涂层钛植入物骨整合的体内比较研究。
IF 1.9
World Journal of Orthopedics Pub Date : 2023-09-18 DOI: 10.5312/wjo.v14.i9.682
Stanislav Bondarenko, Volodymyr Filipenko, Nataliya Ashukina, Valentyna Maltseva, Gennadiy Ivanov, Iurii Lazarenko, Dmytro Sereda, Ran Schwarzkopf
{"title":"Comparative study <i>in vivo</i> of the osseointegration of 3D-printed and plasma-coated titanium implants.","authors":"Stanislav Bondarenko,&nbsp;Volodymyr Filipenko,&nbsp;Nataliya Ashukina,&nbsp;Valentyna Maltseva,&nbsp;Gennadiy Ivanov,&nbsp;Iurii Lazarenko,&nbsp;Dmytro Sereda,&nbsp;Ran Schwarzkopf","doi":"10.5312/wjo.v14.i9.682","DOIUrl":"https://doi.org/10.5312/wjo.v14.i9.682","url":null,"abstract":"<p><strong>Background: </strong>Total hip arthroplasty is a common surgical treatment for elderly patients with osteoporosis, particularly in postmenopausal women. In such cases, highly porous acetabular components are a favorable option in achieving osseointegration. However, further discussion is needed if use of such acetabular components is justified under the condition of normal bone mass.</p><p><strong>Aim: </strong>To determine the features of osseointegration of two different types of titanium implants [3-dimensional (3D)-printed and plasma-coated titanium implants] in bone tissue of a distal metaphysis in a rat femur model.</p><p><strong>Methods: </strong>This study was performed on 20 white male laboratory rats weighing 300-350 g aged 6 mo. Rats were divided into two groups of 10 animals, which had two different types of implants were inserted into a hole defect (2 × 3 mm) in the distal metaphysis of the femur: Group I: 3D-printed titanium implant (highly porous); Group II: Plasma-coated titanium implant. After 45 and 90 d following surgery, the rats were sacrificed, and their implanted femurs were extracted for histological examination. The relative perimeter (%) of bone trabeculae [bone-implant contact (BIC%)] and bone marrow surrounding the titanium implants was measured.</p><p><strong>Results: </strong>Trabecular bone tissue was formed on the 45<sup>th</sup> day after implantation around the implants regardless of their type. 45 d after surgery, group I (3D-printed titanium implant) and group II (plasma-coated titanium implant) did not differ in BIC% (83.51 ± 8.5 <i>vs</i> 84.12 ± 1 .73; <i>P</i> = 0.838). After 90 d, the BIC% was higher in group I (87.04 ± 6.99 <i>vs</i> 81.24 ± 7.62; <i>P</i> = 0.049), compared to group II. The relative perimeter of the bone marrow after 45 d did not differ between groups and was 16.49% ± 8.58% for group I, and 15.88% ± 1.73% for group II. Futhermore, after 90 d, in group I the relative perimeter of bone marrow was 1.4 times smaller (12.96 ± 6.99 <i>vs</i> 18.76 ± 7.62; <i>P</i> = 0.049) compared to the relative perimeter of bone marrow in group II.</p><p><strong>Conclusion: </strong>The use of a highly porous titanium implant, manufactured with 3D printing, for acetabular components provides increased osseointegration compared to a plasma-coated titanium implant.</p>","PeriodicalId":47843,"journal":{"name":"World Journal of Orthopedics","volume":"14 9","pages":"682-689"},"PeriodicalIF":1.9,"publicationDate":"2023-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/33/e7/WJO-14-682.PMC10514715.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41158804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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