World Journal of Orthopedics最新文献

{"title":"Update on synthetic biomaterials combined with fibrin derivatives for regenerative medicine: Applications in bone defect treatment: Systematic review.","authors":"Bruna Trazzi Pagani, Marcelie Priscila de Oliveira Rosso, Matheus Bento Medeiros Moscatel, Beatriz Flavia de Moraes Trazzi, Marcelo Rodrigues da Cunha, João Paulo Mardegan Issa, Daniela Vieira Buchaim, Rogério Leone Buchaim","doi":"10.5312/wjo.v16.i5.106181","DOIUrl":"10.5312/wjo.v16.i5.106181","url":null,"abstract":"<p><strong>Background: </strong>Bone regeneration is a central focus of regenerative medicine, with applications in orthopedics and dentistry, particularly for treating bone defects caused by trauma, infection, or congenital anomalies. Synthetic biomaterials, often combined with fibrin derivatives, offer promising solutions for bone healing and restoration.</p><p><strong>Aim: </strong>To Explore the increasingly important role of the association of synthetic biomaterials with fibrin in bone regeneration.</p><p><strong>Methods: </strong>Search terms included: \"synthetic biomaterials AND fibrin sealant\", \"hydroxyapatite AND fibrin sealant\", \"tricalcium phosphate AND fibrin sealant\", and \"synthetic biomaterials AND platelet-rich fibrin (PRF)\", resulting in 67 articles. After rigorous screening, 21 articles met the inclusion criteria.</p><p><strong>Results: </strong>The reviewed studies assessed biomaterials like hydroxyapatite (HA), β-tricalcium phosphate (β-TCP), and fibrin-based products. Key findings highlighted the enhanced osteoconductivity and biocompatibility of HA and β-TCP, especially when combined with fibrin sealants. These composites show significant potential for improving cellular adhesion, promoting osteogenic differentiation, and accelerating bone regeneration. The antimicrobial properties and structural support for cell growth of certain biomaterials indicate a promising potential for clinical applications.</p><p><strong>Conclusion: </strong>This systematic review emphasizes the growing role of fibrin-based biomaterials in bone regeneration and urges continued research to improve their clinical use for complex bone defects.</p>","PeriodicalId":47843,"journal":{"name":"World Journal of Orthopedics","volume":"16 5","pages":"106181"},"PeriodicalIF":2.0,"publicationDate":"2025-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12146973/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144267677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Parallax-free panoramic X-ray imaging combined with minimally invasive plate osteosynthesis for treating proximal humeral shaft fractures.","authors":"Wen-Jing Cheng, Jing-Shun Lu, Zhou-Shan Tao, Jia-Bing Xie, Min Yang","doi":"10.5312/wjo.v16.i5.102916","DOIUrl":"10.5312/wjo.v16.i5.102916","url":null,"abstract":"<p><strong>Background: </strong>The objective of this study was to evaluate the use of combined parallax-free panoramic X-ray imaging during surgery by enabling the mobile C-arm with minimally invasive plate osteosynthesis (MIPO) in the management of proximal humeral shaft fractures.</p><p><strong>Aim: </strong>To evaluate parallax-free panoramic X-ray images during surgery.</p><p><strong>Methods: </strong>A retrospective series of 17 proximal humeral shaft fractures were treated using combined parallax-free panoramic X-ray imaging during surgery by enabling the mobile C-arm with MIPO. The operating time and radiation exposure time were recorded, and early postoperative physical therapy and partial weight bearing were encouraged. Patients were followed at regular intervals and evaluated radiographically and clinically.</p><p><strong>Results: </strong>The mean operating time and radiation time were 73 (range, 49-95) minutes and 57 (range: 36-98) seconds, respectively. No complications occurred during the operation. All fractures healed at an average of 16.9 (range: 15-23) weeks. The average Constant-Murley score for all the patients was 89.5 (range: 75-100) points. None of the patients showed symptoms of vascular or nerve damage or wound infection. Three months after the operation, none of the patients developed subacromial impingement syndrome. No loosening or fracture of the implants occurred. The frontal and lateral radiographs showed good alignment.</p><p><strong>Conclusion: </strong>We consider that MIPO with combined parallax-free panoramic X-ray imaging during surgery is an efficient method for treating proximal humeral shaft fractures, and could significantly reduce operative morbidity as well as lower the rate of intra- and postoperative complications.</p>","PeriodicalId":47843,"journal":{"name":"World Journal of Orthopedics","volume":"16 5","pages":"102916"},"PeriodicalIF":2.0,"publicationDate":"2025-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12146976/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144267672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of functional recovery of the knee following total knee arthroplasty in patients with and without ankle symptoms.","authors":"Antea Buterin, Mirela Vuckovic, Sandra Spanja Prpic, Vedrana Zaharija, Martin Nonkovic, Tomislav Prpic","doi":"10.5312/wjo.v16.i5.106004","DOIUrl":"10.5312/wjo.v16.i5.106004","url":null,"abstract":"<p><strong>Background: </strong>Total knee arthroplasty (TKA) aims to restore motion and alleviate pain, enabling patients to return to daily activities. Despite advances in implants, surgery, and perioperative care, patient dissatisfaction rates remain significant.</p><p><strong>Aim: </strong>To determine whether ankle symptoms are associated with inferior results of functional recovery of the knee following TKA.</p><p><strong>Methods: </strong>This prospective study included all patients with advanced knee osteoarthritis who underwent a primary unilateral TKA between August 2019 and December 2019 with data documented by the treating surgeon and outpatient physical therapists. Patients were categorized based on ankle symptoms using the American Orthopaedic Foot and Ankle Society (AOFAS) score: (1) Group 1 (AOFAS ≤ 85, <i>n</i> = 30); and (2) Group 2 (AOFAS > 85, <i>n</i> = 49). Active range of motion (ROM), the Knee Injury and Osteoarthritis Outcome Score (KOOS), and the visual analogue scale (VAS) were compared between two groups.</p><p><strong>Results: </strong>Postoperative KOOS, ROM, and VAS significantly improved in both groups (<i>P</i> < 0.001). However, at three months, KOOS (<i>P</i> = 0.02) and extension motion (<i>P</i> = 0.01) improvements were significantly greater in group 2.</p><p><strong>Conclusion: </strong>These findings suggest that preoperative ankle symptoms may negatively impact early knee functional recovery, particularly in KOOS scores and extension motion.</p>","PeriodicalId":47843,"journal":{"name":"World Journal of Orthopedics","volume":"16 5","pages":"106004"},"PeriodicalIF":2.0,"publicationDate":"2025-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12146978/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144267658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Most vexing problem in pediatric fractures: Epiphyseal fractures.","authors":"Zi-Qi Fan, Yu-Yin Xie, Can Liu, Yi-Fan Chen, Yang-Fei Yi, Zhong-Wen Tang, Jie Wen, Sheng Xiao, Yu-Fei Li","doi":"10.5312/wjo.v16.i5.106265","DOIUrl":"10.5312/wjo.v16.i5.106265","url":null,"abstract":"<p><p>Epiphyseal fracture is a significant etiology of limb deformity in children following fractures. However, unlike the rapid advancements in orthopedics, progress regarding the pathological changes, diagnosis, and treatment of epiphyseal fractures has been slow. This review provides an overview of the epidemiology and classification of epiphyseal fractures, as well as the post-fracture pathological changes occurring within the epiphysis and its surrounding areas. Furthermore, it reviews recent advancements in the treatment of epiphyseal fractures. By summarizing laboratory-to-clinical progress related to this type of fracture, this article aims to assist pediatric orthopedists in accurately recognizing, diagnosing, and treating such injuries.</p>","PeriodicalId":47843,"journal":{"name":"World Journal of Orthopedics","volume":"16 5","pages":"106265"},"PeriodicalIF":2.0,"publicationDate":"2025-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12146971/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144267662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of post-operative X-rays in distal-radius fractures among pediatric patients.","authors":"Ammar K Alomran, Bandar A Alzahrani, Dana S Alamoud, Layan S Alsultan, Meshail M AlSaud, Raneem G Althobaiti, Badriah S Alruwaili","doi":"10.5312/wjo.v16.i5.105590","DOIUrl":"10.5312/wjo.v16.i5.105590","url":null,"abstract":"<p><strong>Background: </strong>In pediatric age group patients (< 18 years old) treated operatively for distal radius/both bone fractures extending imaging beyond the initial postoperative period -particularly in uncomplicated cases - appears to provide limited additional benefit.</p><p><strong>Aim: </strong>To determine the necessary number of follow-up X-rays to use resources efficiently.</p><p><strong>Methods: </strong>Participants included in this study are pediatric age group patients who were treated operatively for distal radius/both bone fractures and were identified from a prospected collected data from the operating room database between the years 2009 and 2017. The data in the study included patients who had distal radius fractures and underwent fixation surgery (<i>n</i> = 88).</p><p><strong>Results: </strong>When assessing the difference in the odds of conducting 1 or less X-ray compared to 2 or more X-rays in regard to the type of fixation, the only significant difference is the closed reduction fixation method. Patients who underwent closed reduction method procedure have significantly lower odds of having 2 more X-rays compared to those who didn't have closed reduction method. Open reduction, internal fixation, and other fixation methods (close reduction and internal fixation, debridement, or epiphysiodesis) have higher odds of having two or more X-rays compared to patients who did not receive these methods; however, these odds are not statistically significant.</p><p><strong>Conclusion: </strong>The findings of this study reveal notable absence of a statistically significant association between the frequency of postoperative X-rays and the outcome of children with distal radius fractures.</p>","PeriodicalId":47843,"journal":{"name":"World Journal of Orthopedics","volume":"16 5","pages":"105590"},"PeriodicalIF":2.0,"publicationDate":"2025-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12146974/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144267676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Medial cortical reduction does not influence outcomes in geriatric intertrochanteric femur fractures treated with proximal femoral nail.","authors":"Prabu Mounisamy, Hanoop Suresh, Sushma Chandrashekar, Udayakumar D, Naveen Jeyaraman, Madhan Jeyaraman, Sathish Muthu","doi":"10.5312/wjo.v16.i4.106862","DOIUrl":"https://doi.org/10.5312/wjo.v16.i4.106862","url":null,"abstract":"<p><strong>Background: </strong>In intertrochanteric fractures, the positive medial cortex support reduction is considered to provide a non-anatomical buttress that helps in controlled collapse.</p><p><strong>Aim: </strong>To analyze the concept of medial cortical reduction (MCR) and its clinical and radiological association in geriatric intertrochanteric femur fractures.</p><p><strong>Methods: </strong>Geriatric patients who presented with AO/OTA 31A1 and 31A2 femur fractures and treated with proximal femoral nailing between July 2021 and June 2023 were include in this prospective cohort study. Based on the degree of MCR, they were divided into positive, neutral, or negative MCR groups. The demographic baseline characteristics, postoperative radiographic femoral neck-shaft angle and neck length were analyzed at 6, 12 and 24 weeks post-surgery. Functional outcomes such as modified Harris Hip Score (HHS) and time to full-weight bearing were also analyzed.</p><p><strong>Results: </strong>47 patients (Male: Famale 35:12) with mean age of 65.8 ± 4.2 years were included in this study. Twenty-two cases had neutral support, nine had negative support, and sixteen had positive support in the medial cortex post-operatively. Baseline characteristics of the three groups were comparable. No significant differences were found in the femur neck length and femur neck-shaft angle changes post-surgery between the groups. The modified HHS was not found to be significant between the groups (<i>P</i> = 0.883) as that of the time to full weight bearing (<i>P</i> = 0.789).</p><p><strong>Conclusion: </strong>The type of reduction achieved based on medial cortical alignment does not affect the femur neck length shortening or varus collapse. Future randomized controlled trials are needed to validate the findings noted in the study.</p>","PeriodicalId":47843,"journal":{"name":"World Journal of Orthopedics","volume":"16 4","pages":"106862"},"PeriodicalIF":2.0,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12019145/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143992219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"First metatarsophalangeal joint: Embryology, anatomy and biomechanics.","authors":"Osama M Embaby, Mohamed M Elalfy","doi":"10.5312/wjo.v16.i4.102506","DOIUrl":"https://doi.org/10.5312/wjo.v16.i4.102506","url":null,"abstract":"<p><p>The first metatarsophalangeal (MTP) joint plays a crucial role in foot biomechanics, particularly in weight-bearing activities such as walking and running. It is frequently affected by conditions like hallux valgus (HV) and hallux rigidus, with HV impacting approximately 23%-35% of the population. This narrative review explores the embryology, anatomy, and biomechanics of the first MTP joint (MTPJ), highlighting its significance in maintaining foot stability and function. A comprehensive literature search was conducted using PubMed, Scopus, and Google Scholar, analyzing 50 relevant studies, including 12 clinical trials. The joint's complex structure and mechanical demands make it susceptible to degenerative and structural disorders. Studies indicate that 25%-40% of individuals with HV experience significant pain and functional impairment, affecting mobility and quality of life. Biomechanical stress, abnormal gait patterns, and joint instability contribute to disease progression. Understanding the anatomical and biomechanical properties of the first MTPJ is essential for improving diagnostic and therapeutic approaches. Emerging surgical techniques, such as osteotomy and joint resurfacing, show promise in reducing recurrence rates and enhancing long-term outcomes. Further research is needed to refine minimally invasive interventions and optimize treatment strategies for first MTPJ disorders.</p>","PeriodicalId":47843,"journal":{"name":"World Journal of Orthopedics","volume":"16 4","pages":"102506"},"PeriodicalIF":2.0,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12019138/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144045046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accuracy of artificial intelligence in prediction of osteoporotic fractures in comparison with dual-energy X-ray absorptiometry and the Fracture Risk Assessment Tool: A systematic review.","authors":"Mir Sadat-Ali, Bandar A Alzahrani, Turki S Alqahtani, Musaad A Alotaibi, Abdallah M Alhalafi, Ahmed A Alsousi, Abdullah M Alasiri","doi":"10.5312/wjo.v16.i4.103572","DOIUrl":"https://doi.org/10.5312/wjo.v16.i4.103572","url":null,"abstract":"<p><strong>Background: </strong>Osteoporotic fractures, whether due to postmenopausal or senile causes, impose a significant financial burden on developing countries and diminish quality of life. Recent advancements in artificial intelligence (AI) algorithms have demonstrated immense potential in predicting osteoporotic fractures.</p><p><strong>Aim: </strong>To assess and compare the efficacy of AI models against dual-energy X-ray absorptiometry (DXA) and the Fracture Risk Assessment Tool (FRAX) in predicting fragility fractures.</p><p><strong>Methods: </strong>We conducted a literature search in English using electronic databases, including PubMed, Web of Science, and Scopus, for studies published until May 2024. The keywords employed were fragility fractures, osteoporosis, AI, deep learning, machine learning, and convolutional neural network. The inclusion criteria for selecting publications were based on studies involving patients with proximal femur and vertebral column fractures due to osteoporosis, utilizing AI algorithms, and analyzing the site of fracture and accuracy for predicting fracture risk using SPSS version 29 (Chicago, IL, United States).</p><p><strong>Results: </strong>We identified 156 publications for analysis. After applying our inclusion criteria, 24489 patients were analyzed from 13 studies. The mean area under the receiver operating characteristic curve was 0.925 ± 0.69. The mean sensitivity was 68.3% ± 15.3%, specificity was 85.5% ± 13.4%, and positive predictive value was 86.5% ± 6.3%. DXA showed a sensitivity of 37.0% and 74.0%, while FRAX demonstrated a sensitivity of 45.7% and 84.7%. The <i>P</i> value for sensitivity between DXA and AI was < 0.0001, while for FRAX it was < 0.0001 and 0.2.</p><p><strong>Conclusion: </strong>This review found that AI is a valuable tool to analyze and identify patients who will suffer from fragility fractures before they occur, demonstrating superiority over DXA and FRAX. Further studies are necessary to be conducted across various centers with diverse population groups, larger datasets, and a longer duration of follow-up to enhance the predictive performance of the AI models before their universal application.</p>","PeriodicalId":47843,"journal":{"name":"World Journal of Orthopedics","volume":"16 4","pages":"103572"},"PeriodicalIF":2.0,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12019139/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144045035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Senility, defecation disorders, sleep disorders, and non-operative spinal infections: A single-center retrospective analysis.","authors":"Ling-Ling Guo, Hong-Kun Liu, Jin-Feng Cao, Hai-Xia Zhang, Bo Li, Tong Li, Liang Li","doi":"10.5312/wjo.v16.i4.103388","DOIUrl":"https://doi.org/10.5312/wjo.v16.i4.103388","url":null,"abstract":"<p><strong>Background: </strong>Non-operative spinal infections (NOSI) are caused by tuberculosis, brucella, and other specific bacteria. The etiology of the disease is insidious, the onset is slow and the diagnosis and treatment are difficult. Identifying the factors associated with spinal infection and early intervention can reduce the occurrence of the disease. At present, the research mainly focuses on the accurate diagnosis and treatment of spinal infection, and there are few studies on the prevention of spinal infection. The concept of \"preventive treatment of diseases\" in traditional Chinese medicine may help identify the causes and reduce the occurrence of NOSI.</p><p><strong>Aim: </strong>To determine the association of age, bowel movements, and sleep patterns with NOSI.</p><p><strong>Methods: </strong>Data of 69 NOSI patients and 84 healthy controls in a tertiary hospital from January 2019 to June 2024 were collected. Patients with NOSI had imaging evidence (magnetic resonance imaging) of spinal infections (including infections caused by tuberculosis, brucopathy, and other pathogens) and had no history of spinal surgery in the last 1 year were included in the analysis. Patients with spinal infection due to spinal surgery are excluded in the study. Data including age, sex, place of residence, sleeping status, and bowel movements were collected. SPSS22.0 was used for correlation analysis of all data.</p><p><strong>Results: </strong>The mean age of the NOSI group and the control group was 63.55 ± 14.635 years and 59.18 ± 17.111 years, respectively, without statistical difference (<i>P</i> = 0.096). There was also no statistically significant difference in gender between the two groups. In the NOSI group, 45 (65.22%) were over 60 years old, and 44 (63.77%) were rural residents. Compared with the control group, the NOSI group had more patients with sleep disorder and defecation disorder, accounting for 69.57% and 68.12%, respectively, with significant statistical difference (both <i>P</i> < 0.001). Regression analysis showed that defecation and sleep disorders were closely related to NOSI (both <i>P</i> < 0.001).</p><p><strong>Conclusion: </strong>Most patients with NOSI are older and have sleep disorders and abnormal defecation.</p>","PeriodicalId":47843,"journal":{"name":"World Journal of Orthopedics","volume":"16 4","pages":"103388"},"PeriodicalIF":2.0,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12019144/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144046710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validity of the Arabic version of AAOS-foot and ankle outcomes questionnaire in patients with traumatic foot and ankle injuries.","authors":"Sulaiman A AlMousa, Mohammad M Alzahrani, Bandar A Alzahrani, Ahmed K Alsenan, Abdulraheem A Altalib, Hashem Abdulkarim Alkhamis","doi":"10.5312/wjo.v16.i4.103463","DOIUrl":"https://doi.org/10.5312/wjo.v16.i4.103463","url":null,"abstract":"<p><strong>Background: </strong>Arabic-speaking patients are underrepresented in orthopedic clinical studies, particularly in foot and ankle trauma research. The lack of validated Arabic language tools hinders their inclusion, creating a need for culturally and linguistically adapted instruments. The American Academy of Orthopedic Surgeons Foot and Ankle Outcomes Questionnaire (AAOS-FAOQ) is a widely used tool but has not been adapted for Arabic-speaking patients.</p><p><strong>Aim: </strong>To translate, cross-culturally adapt, and validate the AAOS-FAOQ for Arabic-speaking patients with traumatic foot and ankle injuries.</p><p><strong>Methods: </strong>The cross-cultural adaptation followed established guidelines, involving forward and backward translations, expert review, and pre-testing. The final Arabic version was administered alongside the Arabic Short-Form 36 (SF-36) to 100 patients for validity testing. Reliability was assessed through test-retest methods with 20 patients completing the questionnaire twice within 48 hours. Pearson correlation coefficients measured convergent and divergent validity with SF-36 subscales, while Cronbach's alpha and intraclass correlation coefficients (ICC) determined internal consistency and reliability.</p><p><strong>Results: </strong>Out of 100 patients, 92 completed the first set of questionnaires. The Arabic AAOS-FAOQ showed strong correlations with the SF-36 subscales, particularly in physical function and bodily pain (<i>r</i> > 0.6). Test-retest reliability was robust, with ICCs of 0.69 and 0.66 for the Global Foot and Ankle Scale and Shoe Comfort Scale, respectively. Cronbach's alpha for internal consistency ranged from 0.7 to 0.9.</p><p><strong>Conclusion: </strong>The Arabic version of the AAOS-FAOQ demonstrated validity and reliability for use in Arabic-speaking patients with traumatic foot and ankle injuries. This adaptation will enhance the inclusion of this population in orthopedic clinical studies, improving the generalizability of research findings and patient care.</p>","PeriodicalId":47843,"journal":{"name":"World Journal of Orthopedics","volume":"16 4","pages":"103463"},"PeriodicalIF":2.0,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12019141/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143990826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}