Lung India最新文献

{"title":"Delayed blast lung injury following a truck tyre explosion in a civilian.","authors":"V Ramkishore, Praveen Dubey, Ajoy K Behera, Manish Kumar, Ranganath Ganga","doi":"10.4103/lungindia.lungindia_29_26","DOIUrl":"https://doi.org/10.4103/lungindia.lungindia_29_26","url":null,"abstract":"","PeriodicalId":47462,"journal":{"name":"Lung India","volume":"43 3","pages":"347-349"},"PeriodicalIF":1.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147844377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safety and major adverse events of endobronchial ultrasound performed under conscious sedation: Insights from 3,454 procedures over 14 years and a systematic review of literature.","authors":"Babu Ram, Valliappan Muthu, Inderpaul S Sehgal, Sahajal Dhooria, Kuruswamy T Prasad, Ashutosh N Aggarwal, Ritesh Agarwal","doi":"10.4103/lungindia.lungindia_436_25","DOIUrl":"https://doi.org/10.4103/lungindia.lungindia_436_25","url":null,"abstract":"<p><strong>Background: </strong>Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is widely used for evaluating mediastinal lymphadenopathy. However, its safety profile requires comprehensive evaluation. This study aimed to determine the prevalence of complications associated with EBUS-TBNA and to conduct a systematic review and meta-analysis to estimate the pooled complication rates.</p><p><strong>Methods: </strong>We retrospectively analysed a prospectively maintained database of patients who underwent EBUS between April 2011 and April 2025. We extracted demographic, procedural, and complication-related data. Major complications were defined as events necessitating endotracheal intubation, cardiopulmonary arrest, hospitalization ≥24 h, mediastinitis, significant bleeding requiring intervention, pneumothorax unrelated to transbronchial biopsy, or death. A systematic review and meta-analysis were performed using the Der Simonian and Laird random-effects model to determine pooled complication rates from studies with ≥1000 EBUS procedures.</p><p><strong>Results: </strong>Of the 3,454 patients included 77 (2.2%) experienced complications, with 10 (0.3%) classified as major. Major events included severe bleeding ( n = 4), respiratory arrest ( n = 2), mediastinal cyst rupture, mediastinitis, temporomandibular joint dislocation, and one death. The meta-analysis included 27,560 patients from seven studies and yielded a pooled complication rate of 1.21%. The pooled complication rates from our meta-analysis were 26.2 for major bleeding, 9.6 for mediastinitis, 5.5 for pneumothorax, and 1.52 for procedure-related mortality per 10,000 EBUS procedures.</p><p><strong>Conclusions: </strong>EBUS-TBNA is a safe diagnostic procedure with a rare incidence of major complications. Bleeding, infectious complications, and respiratory events constitute the most significant risks.</p>","PeriodicalId":47462,"journal":{"name":"Lung India","volume":"43 3","pages":"245-252"},"PeriodicalIF":1.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147844489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrating pulmonary rehabilitation into post-tuberculosis care: Evidence-based rationale for policy change in high tuberculosis burden countries.","authors":"Ramakant Dixit, Manudev Mehta","doi":"10.4103/lungindia.lungindia_537_25","DOIUrl":"https://doi.org/10.4103/lungindia.lungindia_537_25","url":null,"abstract":"<p><p>Post-tuberculosis sequelae (PTBS) constitute a significant but underrecognised global health burden, especially in high TB-incidence countries. Although the microbiological cure of tuberculosis (TB) is prioritised within national TB programmes, residual structural and functional pulmonary impairments often persist. Pulmonary rehabilitation (PR)-a multidisciplinary intervention has shown compelling efficacy in addressing chronic respiratory limitations, psychological distress, and compromised quality of life in PTBS patients. This review consolidates current evidence, including findings from different interventional study in India, to propose integration of PR into routine post-TB care and advocate for its inclusion in national policies in high-burden settings.</p>","PeriodicalId":47462,"journal":{"name":"Lung India","volume":"43 3","pages":"323-326"},"PeriodicalIF":1.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147844508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"THRIVE: An unexplored technique for bronchoscopy.","authors":"Poonam Godhwal, Nishkarsh Gupta, Karan Madan","doi":"10.4103/lungindia.lungindia_66_25","DOIUrl":"https://doi.org/10.4103/lungindia.lungindia_66_25","url":null,"abstract":"<p><p>Trans-nasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) has emerged as a promising technique for prolonging safe apnea time while maintaining oxygenation during airway procedures. This case highlights the successful application of THRIVE as a respiratory support modality during interventional bronchoscopy. By ensuring adequate oxygenation, reducing airway trauma, and improving procedural conditions, THRIVE proves to be a valuable alternative to conventional ventilation techniques in select airway interventions.</p>","PeriodicalId":47462,"journal":{"name":"Lung India","volume":"43 3","pages":"337-339"},"PeriodicalIF":1.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147844607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phenotyping and unmet need assessment for biological agents in uncontrolled asthma.","authors":"Rahul Tyagi, Randeep Guleria, Pawan Tiwari, Karan Madan, Anant Mohan, Vijay Hadda, Ravindra Mohan Pandey, Saurabh Mittal","doi":"10.4103/lungindia.lungindia_464_25","DOIUrl":"https://doi.org/10.4103/lungindia.lungindia_464_25","url":null,"abstract":"<p><strong>Setting: </strong>Uncontrolled asthma patients at a university teaching hospital in India.</p><p><strong>Objective: </strong>To determine the prevalence, endotypes, and need for add-on therapies in severe asthma.</p><p><strong>Methods: </strong>This prospective study screened all patients with uncontrolled asthma, and those with uncontrolled asthma while on moderate-to-high dose inhaled corticosteroids with long-acting beta agonists (ICS + LABA) were further assessed. Endotyping and optimisation of therapy for all potentially modifiable factors were performed, followed by reassessment at 3 months of optimised treatment. Uncontrolled patients at 3 months were classified as having severe asthma and assessed for eligibility for add-on therapies.</p><p><strong>Results: </strong>After screening 261 uncontrolled asthma patients, 160 patients with uncontrolled asthma on moderate-high dose ICS + LABA were included in the study (prevalence of difficult-to-treat asthma: 61.2%). On endotyping, 134 (83.75%) had T2-high endotype and 26 (16.25%) had T2-low endotype asthma. Severe asthma prevalence was 20% (32 out of 160) in this subgroup, and they were assessed for eligibility for guideline-directed add-on therapy: 12 (37.5%) were eligible for omalizumab; 18 (56.25%) were eligible for mepolizumab, benralizumab, or dupilumab; and seven (21.87%) were not eligible for any add-on therapy.</p><p><strong>Conclusion: </strong>T2-high asthma is five times more common than T2-low asthma, and the prevalence of severe asthma is 20% among uncontrolled asthmatics.</p>","PeriodicalId":47462,"journal":{"name":"Lung India","volume":"43 3","pages":"266-270"},"PeriodicalIF":1.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147844459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Non-tubercular mycobacterial infections: Emerging from the shadows.","authors":"Anant Mohan, Tejas Suri","doi":"10.4103/lungindia.lungindia_268_26","DOIUrl":"https://doi.org/10.4103/lungindia.lungindia_268_26","url":null,"abstract":"","PeriodicalId":47462,"journal":{"name":"Lung India","volume":"43 3","pages":"243-244"},"PeriodicalIF":1.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147844480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Late expectoration of an arterial hemolock clip after segmentectomy for pulmonary fibrohistiocytic tumour.","authors":"Hasan Emre Yildirim, Hasan Ekrem Camas, Suleyman Emre Akin, Isa Dongel","doi":"10.4103/lungindia.lungindia_21_26","DOIUrl":"https://doi.org/10.4103/lungindia.lungindia_21_26","url":null,"abstract":"","PeriodicalId":47462,"journal":{"name":"Lung India","volume":"43 3","pages":"341-343"},"PeriodicalIF":1.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147844495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spontaneous lung herniation due to congenital rib hypoplasia in an elderly patient.","authors":"Ekaterina S Zinovkina, Dmitry A Zinovkin, Samira S A Al-Shiekh, Zahidul I Pranjol Md","doi":"10.4103/lungindia.lungindia_125_26","DOIUrl":"https://doi.org/10.4103/lungindia.lungindia_125_26","url":null,"abstract":"","PeriodicalId":47462,"journal":{"name":"Lung India","volume":"43 3","pages":"349-350"},"PeriodicalIF":1.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147844553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pulmonary mycobacterial spindle cell pseudotumour: Report of a case and systematic review of literature.","authors":"Rakesh Kodati, Narendra Kumar Narahari, Shantveer G Uppin, Ranganath Ratnagiri, Sujata Patnaik, Kavitha Nair, Paramjyothi Gongati","doi":"10.4103/lungindia.lungindia_395_25","DOIUrl":"https://doi.org/10.4103/lungindia.lungindia_395_25","url":null,"abstract":"<p><p>Mycobacterial spindle cell pseudotumour (MSP) is a rare benign disease characterized by proliferation of spindle-shaped histiocytes containing acid-fast mycobacteria. Most of the reported cases occur in lymph nodes and skin, predominantly in immunocompromised patients, particularly those with human immunodeficiency virus (HIV) infection or after organ transplantation. The occurrence of MSP in the pulmonary parenchyma is less common. We describe a case of MSP arising in a lung sequestration in an immunocompetent host and present a systematic review of all cases of pulmonary MSP reported in the English literature.</p>","PeriodicalId":47462,"journal":{"name":"Lung India","volume":"43 3","pages":"327-332"},"PeriodicalIF":1.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147844514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating lung transplant referral and listing in chronic respiratory disease: A single-center experience from a tertiary care centre in India.","authors":"Gaurav Jain, Amita Athavale","doi":"10.4103/lungindia.lungindia_559_25","DOIUrl":"https://doi.org/10.4103/lungindia.lungindia_559_25","url":null,"abstract":"<p><strong>Background: </strong>Patients with advanced chronic respiratory diseases experience severe functional limitation, limited therapeutic options, and high mortality risk. Lung transplantation (LTx) offers potential survival benefit in carefully selected candidates. However, Indian data describing the severity profile and eligibility of such patients are scarce. This study assessed the proportion and characteristics of patients meeting International Society for Heart and Lung Transplantation (ISHLT) referral and listing criteria, along with disease severity, contraindications, and risk factors.</p><p><strong>Methods: </strong>This retrospective observational study included adults admitted between January 2020 and October 2023 with interstitial lung disease, chronic obstructive pulmonary disease, bronchiectasis, or pulmonary vascular disease. Eligibility for LTx was evaluated using 2021 ISHLT consensus criteria. Lung Allocation Score was calculated as per OPTN/UNOS guidelines. ISHLT-defined risk factors, substantially increased risk, and absolute contraindications were recorded.</p><p><strong>Results: </strong>Among 401 patients, 105 (26.2%) met referral and 97 (24.2%) listing criteria. Most demonstrated advanced physiological limitation (mean FVC 44.1% predicted; median ECOG 3). ILD was the leading indication among listing-eligible patients (48.6%), followed by COPD (32.4%) and bronchiectasis (18.1%). LAS was highest in ILD (mean 47.8). ISHLT-defined risk factors were present in 90.5% of referral-eligible patients, with 25.7% showing substantially increased risk and 32.4% absolute contraindications. Findings may overestimate eligibility and severity given the inclusion of only hospitalized patients, limiting broader generalizability to ambulatory patients.</p><p><strong>Conclusion: </strong>A considerable proportion of hospitalized patients with advanced respiratory disease are LTx-eligible, though many have comorbidities or modifiable risks. Early referral and multidisciplinary optimization are essential to improve candidacy.</p>","PeriodicalId":47462,"journal":{"name":"Lung India","volume":"43 3","pages":"283-290"},"PeriodicalIF":1.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147844539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}