Indian Journal of Urology最新文献

{"title":"Talazoparib plus enzalutamide for metastatic castration-resistant prostate cancer: TALAPRO-2 trial.","authors":"Prashant Gupta","doi":"10.4103/iju.iju_307_23","DOIUrl":"https://doi.org/10.4103/iju.iju_307_23","url":null,"abstract":"","PeriodicalId":47352,"journal":{"name":"Indian Journal of Urology","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10704975/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138807702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Triplet combination in metastatic renal cell carcinoma.","authors":"P Jithesh","doi":"10.4103/iju.iju_192_23","DOIUrl":"https://doi.org/10.4103/iju.iju_192_23","url":null,"abstract":"","PeriodicalId":47352,"journal":{"name":"Indian Journal of Urology","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10704969/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138807706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>Post hoc</i> analysis of CheckMate 274 trial for programmed death-ligand 1 expression and outcome.","authors":"Deepak Prakash Bhirud","doi":"10.4103/iju.iju_172_23","DOIUrl":"https://doi.org/10.4103/iju.iju_172_23","url":null,"abstract":"","PeriodicalId":47352,"journal":{"name":"Indian Journal of Urology","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10704977/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138807642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quality: The eternal goal of scientific publishing","authors":"Rajeev Kumar","doi":"10.4103/iju.iju_457_23","DOIUrl":"https://doi.org/10.4103/iju.iju_457_23","url":null,"abstract":"","PeriodicalId":47352,"journal":{"name":"Indian Journal of Urology","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2023-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139334065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of outcomes after open versus robotic kidney transplantation: A systematic review and meta-analysis.","authors":"Kumar Madhavan,&nbsp;Rahul Jena,&nbsp;Priyank Bhargava,&nbsp;Aditya Pradhan,&nbsp;Mahendra Bhandari","doi":"10.4103/iju.iju_390_22","DOIUrl":"10.4103/iju.iju_390_22","url":null,"abstract":"<p><strong>Introduction: </strong>This meta-analysis compares the clinical outcomes of robot-assisted kidney transplant (RAKT) to open kidney transplant (OKT).</p><p><strong>Methods: </strong>A systematic search of Scopus and MEDLINE databases was carried out using a combination of keywords to identify studies comparing RAKT to OKT. Baseline characteristics and preoperative and postoperative data were collected along with data on the short- and long-term outcomes. The study was registered in PROSPERO and Assessing the Methodological Quality of Systematic Reviews and Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines were followed.</p><p><strong>Results: </strong>A total of 16 studies were included with a total of 2555 patients, of which 677 underwent RAKT and 1878 underwent OKT. This meta-analysis shows a significant benefit of RAKT over OKT in terms of less intra-operative blood loss, smaller incision length, less postoperative pain scores at 24 and 48 hours, and a lower incidence of surgical site infections (SSIs), especially in obese patients. In addition, the incidence of postoperative lymphoceles was lower in the RAKT group compared to the OKT group, although not statistically significant. There was no difference between the two groups in terms of short-term graft functional outcomes and overall survival. The number of deceased donor recipients undergoing RAKT was very small. At the time of reporting this meta-analysis, no randomized controlled trials (RCTs) had been published.</p><p><strong>Conclusion: </strong>This meta-analysis showed that RAKT is a safe and feasible alternative to OKT, especially in obese individuals. Further trials are needed to confirm the safety, efficacy, and cost-effectiveness of RAKT.</p>","PeriodicalId":47352,"journal":{"name":"Indian Journal of Urology","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/24/a6/IJU-39-186.PMC10419774.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10350988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Re: Budukh AM, Thakur JS, Dora TK, Kadam PR, Bagal SS, Patel KK, <i>et al</i>. Overall survival of prostate cancer from Sangrur and Mansa cancer registries of Punjab state, India. Indian J Urol 2023;39:148.","authors":"Soumya Shivasis Pattnaik","doi":"10.4103/iju.iju_186_23","DOIUrl":"10.4103/iju.iju_186_23","url":null,"abstract":"","PeriodicalId":47352,"journal":{"name":"Indian Journal of Urology","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/6f/e5/IJU-39-252.PMC10419767.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10052257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Medical conferences: Limitation or liberal escalation.","authors":"Rishi Nayyar","doi":"10.4103/iju.iju_173_23","DOIUrl":"10.4103/iju.iju_173_23","url":null,"abstract":"Conferences are an important and integral part of scientific networking and exchange of ideas, while simultaneously providing an opportunity to showcase scientific work and staying abreast with technology and trade. Of late, the number of medical conferences being held has increased exponentially, seemingly outgrowing their need and demand. Herd mentality seems to have engulfed the society from its highest echelons to its lowest levels, each organizing a multitude of conferences in various forms. But, as a responsible society, should we be concerned? We need to understand the needs of students, practicing urologists, teachers, institutions, and the society at large and how conferences may help fulfill these needs before we draw any conclusion about limiting or escalating the number of conferences. For each of these elements of the society, the ideal conference would vary not only in terms of numbers but also their nature, content, mode, and delivery. For a senior urologist, a conference every weekend is unlikely to be of any benefit professionally or otherwise, particularly when the same set of individuals are involved as the core group.","PeriodicalId":47352,"journal":{"name":"Indian Journal of Urology","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/cf/45/IJU-39-179.PMC10419773.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10052259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Socio-economic, education, and insurance-related factors associated with the treatment completion rates in patients with nonmetastatic urinary bladder cancer: A Retrospective cohort study.","authors":"Gorrepati Rohith,&nbsp;Abhay Singh Gaur,&nbsp;Prasant Nayak,&nbsp;Swarnendu Mandal,&nbsp;Manoj K Das,&nbsp;Santosh Kumaraswamy,&nbsp;Vivek Tarigopula,&nbsp;Sambit Tripathy","doi":"10.4103/iju.iju_116_23","DOIUrl":"10.4103/iju.iju_116_23","url":null,"abstract":"<p><strong>Introduction: </strong>Among urological malignancies, the diagnosis and treatment of urinary bladder cancer (UBC) incurs the highest cost per patient. Our objective was to broaden the current understanding of how demographic, socioeconomic, education, and insurance-related factors influence UBC management.</p><p><strong>Methods: </strong>Between January 2017 and December 2019, all patients with nonmetastatic bladder cancer were included. The demographic, treatment, and follow-up details were retrieved from a prospectively maintained database, and the Modified Kuppuswamy Index was used to evaluate the patients' socioeconomic level. Patients were divided into the completed treatment group, or the incomplete treatment group based on adherence to the initially intended treatment plan. Patients who presented with benign disease or metastases were not included.</p><p><strong>Results: </strong>Eighty-nine patients did not complete the initially intended course of treatment out of 132 patients who needed additional management after the initial transurethral resection. Comparable risk factors and demographic profiles existed in both groups. Patients with intermediate-risk disease are more likely to fail to adhere to the initial intended treatment (odds ratio [OR] = 0.09; 95% confidence interval [CI]: 0.02-0.30). On logistic regression analysis, upper socioeconomic status (OR = 6.8; 95% CI: 0.35-132.1) patients and patients with higher educational status of graduation or above (OR = 3.62; 95% CI: 0.75-17.43) had higher chances of treatment completion. Education status significantly impacted treatment completion on multivariate analysis (<i>P</i> = 0.01). Patients who utilized employer-funded insurance had better treatment compliance (OR = 4.1; 95% CI: 0.90-18.7). The compliance was unaffected by smoking, occupation, or other demographic factors.</p><p><strong>Conclusion: </strong>Patients with low economic status, low levels of education, and who need adjuvant intravesical therapy had considerably greater treatment dropout rates.</p>","PeriodicalId":47352,"journal":{"name":"Indian Journal of Urology","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/31/c7/IJU-39-228.PMC10419770.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10052255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"What's inside?","authors":"Abhishek Singh","doi":"10.4103/iju.iju_225_23","DOIUrl":"10.4103/iju.iju_225_23","url":null,"abstract":"","PeriodicalId":47352,"journal":{"name":"Indian Journal of Urology","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a1/4a/IJU-39-181.PMC10419783.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10044819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Author Reply Re: Wirjopranoto S. Comparison between neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio as predictors of mortality on Fournier's gangrene cases. Indian J Urol 2023;39:121-5.","authors":"Soetojo Wirjopranoto","doi":"10.4103/iju.iju_183_23","DOIUrl":"10.4103/iju.iju_183_23","url":null,"abstract":"","PeriodicalId":47352,"journal":{"name":"Indian Journal of Urology","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/71/b1/IJU-39-255.PMC10419766.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10052256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}