{"title":"Comparison of the duration of androgen deprivation therapy in prostate cancer-RADICALS-HD trial.","authors":"Prabhu E Rajendran","doi":"10.4103/iju.iju_347_24","DOIUrl":"10.4103/iju.iju_347_24","url":null,"abstract":"","PeriodicalId":47352,"journal":{"name":"Indian Journal of Urology","volume":"41 1","pages":"75-76"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11778699/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143068818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Neoadjuvant chemotherapy for bladder cancer: Two decades on.","authors":"Rishi Nayyar","doi":"10.4103/iju.iju_432_24","DOIUrl":"10.4103/iju.iju_432_24","url":null,"abstract":"","PeriodicalId":47352,"journal":{"name":"Indian Journal of Urology","volume":"41 1","pages":"1-2"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11778688/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143068872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Shifting tides: A survey analysis of urologists' evolving attitudes toward focal therapy for prostate cancer.","authors":"Jason Koehler, Alon Lazarovich, Shima Tayebi, Vijay Viswanath, Arvin George, Wei-Wen Hsu, Abhinav Sidana","doi":"10.4103/iju.iju_239_24","DOIUrl":"10.4103/iju.iju_239_24","url":null,"abstract":"<p><strong>Introduction: </strong>Focal therapy (FT) is emerging as an alternative to radical treatment for prostate cancer (CaP). The purpose of this study is to assess the current perceptions of FT amongst urologists.</p><p><strong>Methods: </strong>A 22-item questionnaire was e-mailed to members of the American Urological Association. Multivariate logistic regression analysis was used to identify predictors of FT utilization. Results were compared to a previous survey from 2019.</p><p><strong>Results: </strong>Two hundred and sixty-four responses were recorded. Less than half (115/264, 43.6%) of respondents utilize FT; among them, 42% perform FT on more than 10 patients/year. Reasons for avoiding FT included: lack of experience (51.8%), belief that CaP is multifocal (46.0%), and lack of infrastructure (43.1%). The most common modalities for FT were high-intensity focused ultrasound (63.4%) and cryoablation (47.3%). Preferred patients for FT were primarily unilateral/anterior only Gleason Grade Group 2 (95/110, 86.4%). A fellowship training in urologic oncology (odds ratio [OR] = 2.86, <i>P</i> = 0.008) and seeing more than 10 CaP patients per month (OR = 2.46, <i>P</i> = 0.002) were associated with greater utilization of FT. Most respondents (85.4%) cited better imaging methods as a factor that has increased FT utilization. Compared to a previous survey, a higher number of respondents (43% vs. 24%) utilize FT and more respondents believe in the \"index lesion theory.\"</p><p><strong>Conclusions: </strong>Less than half of the respondents utilize FT in their practice. Fellowship training in urologic oncology and a higher volume of CaP patients were correlated with FT utilization. As urologists gain more experience, the trend of further utilization of FT for CaP may continue.</p>","PeriodicalId":47352,"journal":{"name":"Indian Journal of Urology","volume":"41 1","pages":"59-65"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11778692/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143068447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Courtney Yong, Yan Tong, Mark Tann, Chandru Sundaram
{"title":"Reply to Letter for the Article, the Impact of Sestamibi Scan on Clinical Decision-Making for Renal Masses: An Observational Single-center Study. Yong, Courtney; Tong, Yan; Tann, Mark; Sundaram, Chandru P. Indian Journal of Urology. 40(3):151-155, Jul-Sep 2024.","authors":"Courtney Yong, Yan Tong, Mark Tann, Chandru Sundaram","doi":"10.4103/iju.iju_424_24","DOIUrl":"https://doi.org/10.4103/iju.iju_424_24","url":null,"abstract":"","PeriodicalId":47352,"journal":{"name":"Indian Journal of Urology","volume":"41 1","pages":"78-79"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11778693/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143068472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Urethral duplication with five openings in anal canal: A novel case report.","authors":"Faisal Masood Pirzada, Rishi Nayyar, Devendra Kumar Yadav","doi":"10.4103/iju.iju_264_24","DOIUrl":"10.4103/iju.iju_264_24","url":null,"abstract":"<p><p>Urethral duplication is a rare congenital anomaly characterized by more than one urethral channel, with varied course, location of the external opening, and presentation. Presentations can be varied, depending upon individual anatomical dispensation but mostly present as obstruction, recurrent urinary infection, or double urinary stream. Treatment depends on the type of duplication and associated anomalies. Here, we report a case of urethral duplication which did not fit into any known reported type of urethral duplication forms and had five openings at the anal verge.</p>","PeriodicalId":47352,"journal":{"name":"Indian Journal of Urology","volume":"41 1","pages":"69-72"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11778702/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143068594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Can lesion volume and prostate-specific antigen density play a role in detecting clinically significant prostate cancer in Prostate Imaging Reporting and Data System-3 lesions on multiparametric magnetic resonance imaging?","authors":"Shashank Agrawal, Vishnu Prasad, Arun Ramadas Menon, Ginil Kumar Pooleri","doi":"10.4103/iju.iju_112_24","DOIUrl":"10.4103/iju.iju_112_24","url":null,"abstract":"<p><strong>Introduction: </strong>Recently, the Prostate Imaging Reporting and Data System - 3 lesions (PI-RADS 3) have been sub classified into \"3a\" - lesions with a volume of <0.5 mL and \"3b\" - lesions exceeding 0.5 mL, whereas the prostate-specific antigen density (PSAD) is an established adjunct tool for predicting clinically significant prostate cancer (csPCa). The objective of this study was to evaluate the association between the volume of PI-RADS 3 lesions and PSAD in diagnosing csPCa and to assess the sensitivity, specificity, negative predictive value (NPV), and positive predictive value (PPV) when PSAD is combined with the lesion volume.</p><p><strong>Methods: </strong>This retrospective single-center study reviewed the data of transperineal prostate biopsies performed under transrectal ultrasound guidance from January 2018 to December 2023. csPCa was defined as a Gleason score ≥3 + 4. Patients were divided into two groups based on the PIRADS-3 subclassification and PSAD.</p><p><strong>Results: </strong>Out of the 108 PIRADS-3 lesions, 17 patients had csPCa. All the patients with PIRADS-3a (<i>n</i> = 37) had clinically insignificant tumors or benign conditions. Receiver operating characteristic curve analysis for predicting csPCa showed that the (Area under the curve) AUC values of PSAD, prostate volume, and prostate-specific antigen were 0.899, 0.746, and 0.381, respectively. 16 csPCa patients in PIRADS-3b category had PSAD ≥0.29 ng/ml<sup>2</sup>, whereas 1 patient had PSAD <0.29 ng/ml<sup>2</sup>. Sensitivity, specificity, PPV, and NPV of PIRADS-3b lesions were 100%, 40.66%, 23.94%, and 100%, respectively, and it became 94.12%, 74.07%, 53.33%, and 97.56%, respectively, when PSAD was added to PIRADS-3b lesions.</p><p><strong>Conclusion: </strong>The combination of lesion volume of the PI-RADS 3 lesion and PSAD improved the PPV and specificity of detecting csPCa.</p>","PeriodicalId":47352,"journal":{"name":"Indian Journal of Urology","volume":"41 1","pages":"35-39"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11778701/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143068791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Single-port robot-assisted pyeloplasty through supine anterior retroperitoneal access.","authors":"Sina Sobhani, Sij Hemal","doi":"10.4103/iju.iju_389_24","DOIUrl":"10.4103/iju.iju_389_24","url":null,"abstract":"<p><p>This video explores the technique of robot-assisted pyeloplasty using the Da-Vinci Single-Port robot through the supine anterior retroperitoneal access in a 28-year-old male with a right-sided ureteropelvic junction obstruction. The patient was placed in a supine position, with a 10°-20° elevation of the ipsilateral flank. Retroperitoneal access was obtained at the McBurney's point for the placement of the port. The standardized steps of the Anderson-Hynes pyeloplasty technique were executed. Operative time was 120 min with 10 mL of blood loss. The patient was discharged on the same day without complications. At 4-months follow-up, on the renal scan, the right kidney showed stable function with improved drainage.</p>","PeriodicalId":47352,"journal":{"name":"Indian Journal of Urology","volume":"41 1","pages":"73-74"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11778694/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143068517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}