Indian Journal of Urology最新文献

{"title":"PROMPTS Trial: Screening spinal magnetic resonance imaging in castration-resistant prostate cancer.","authors":"Soumya Shivasis Pattnaik","doi":"10.4103/iju.iju_21_23","DOIUrl":"10.4103/iju.iju_21_23","url":null,"abstract":"SUMMARY The PROMPTS trial [1] is a recently concluded phase 3 trial which was conducted in 45 NHS hospitals in the United Kingdom. It evaluated the role of screening spinal magnetic resonance imaging (MRI) and subsequent treatment of radiological spinal cord compression in asymptomatic patients with metastatic castration-resistant prostate cancer (CRPC) and whether early treatment reduced the incidence of clinical spinal cord compression. This study included patients with an Eastern Cooperative Oncology Group performance status of 0–2, with asymptomatic spinal metastasis without any history of prior spinal cord compression, and no spinal MRI in the past 12 months. Patients were randomized 1:1 into two groups. In one group, screening spinal MRI was done followed by treatment for radiological spinal cord compression (if diagnosed). The other group did not undergo the screening spinal MRI. Patients who were included in the study and had screening detected radiological spinal cord compression were offered treatment in the form of radiotherapy or surgical decompression as recommended by the physician and 6-month spinal MRI was done. All patients were followed up every 3 months, and then at the 30 th and 36 th months. The study evaluated the incidence of confirmed clinical spinal cord compression and the time taken to develop cord compression. The trial enrolled 420 patients, 210 in each arm. Screening MRI detected radiological cord compression in 61 (31%) of 200 patients with assessable scans in the intervention group. At a median follow-up of 22 months (interquartile range: 13–31), time to clinical cord compression was not significantly improved with screening. One-year clinical cord compression rates were 6·7% for the control group and 4·3% for the screening and treatment group. Median time to clinical cord compression was not reached in either group. This study concluded that despite there being a significant incidence of radiological (asymptomatic","PeriodicalId":47352,"journal":{"name":"Indian Journal of Urology","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d7/a3/IJU-39-175.PMC10249523.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9674216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hourglass appearance in cystocele with an impacted vesical calculus.","authors":"Manickam Ramalingam, Senthil Kallappan, M N Janani","doi":"10.4103/iju.iju_20_23","DOIUrl":"10.4103/iju.iju_20_23","url":null,"abstract":"A 62-year-old hypertensive female presented with a mass protruding from the vagina for the past 20 years. She complained of dysuria and urinary incontinence for the past 3 months. There was no history of surgical intervention in the past. The examination revealed a tender irreducible total uterine prolapse (procidentia) and cystocele with a decubitus ulcer. Computed tomography urogram showed a total uterine prolapse along with the prolapse of a part of urinary bladder, with a vesical calculus of size 2.8 cm × 2.7 cm in the prolapsed part of the bladder, below the level of the pubic symphysis, with minimal wall thickening. After optimization, vesical lithotripsy and bilateral ureteric stenting were performed, followed by hysterectomy after 2 days.","PeriodicalId":47352,"journal":{"name":"Indian Journal of Urology","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/29/95/IJU-39-163.PMC10249529.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9674217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Re: Ramadhani MZ, Kloping YP, Rahman IA, Yogiswara N, Soebadi MA, Renaldo J. Silodosin as a medical expulsive therapy for distal ureteral stones: A systematic review and meta-analysis. Indian J Urol 2023;39:21-6.","authors":"Gopal Sharma","doi":"10.4103/iju.iju_439_22","DOIUrl":"10.4103/iju.iju_439_22","url":null,"abstract":"I read with great interest an article published by Ramadhani et al.[1] in the latest edition of the Journal. In this study, the authors have performed a systematic review and meta-analysis of the studies examining the role of silodosin as a medical expulsive therapy for distal ureteric stones. I would like to congratulate the authors on their publication. Multiple randomized control trials have established the efficacy of alpha‐blockers as a part of medical expulsive therapy for distal ureteric stones. Most of the studies conducted in this field have been small, single‐center, poor‐quality randomized studies. Therefore, there is still a scope for a well-conducted multicentric randomized control trial to close this debate. This is where systematic reviews and meta-analyses have proved handy by performing a pooled analysis of these small randomized studies. However, this pooling of data may not be without limitations as there would be heterogeneity in the patient population and outcomes studied. In the present meta-analysis, the authors have tried to handle this delicate issue; however, there are still limitations that need to be addressed.","PeriodicalId":47352,"journal":{"name":"Indian Journal of Urology","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/81/e9/IJU-39-177.PMC10249525.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9993002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pediatric robotic urologic procedures: Indications and outcomes.","authors":"Sean W Hou,&nbsp;Monica H Xing,&nbsp;Mohan S Gundeti","doi":"10.4103/iju.iju_276_22","DOIUrl":"10.4103/iju.iju_276_22","url":null,"abstract":"<p><strong>Introduction: </strong>Robotic-assisted laparoscopic surgery (RALS) has revolutionized minimally invasive surgery in pediatric urology. The robotic platform allows surgeons to maintain the benefits of laparoscopic surgery while having enhanced three-dimensional view, dexterity, range of motion, and control of high-resolution cameras. In this review, we summarize the indications and recent outcomes for various pediatric urologic RALS procedures to illustrate the current state of robotics in pediatric urology.</p><p><strong>Methods: </strong>We systematically searched the PubMed and EMBASE databases. We extrapolated and summarized recent evidence on RALS in pediatric urology patients, with an emphasis on indications and outcomes, with regard to the following procedures and search terms: pyeloplasty, kidney stone surgery, partial nephrectomy, nephroureterectomy, ureteral reimplantation, appendico-vesicostomy, augmentation cystoplasty, bladder neck reconstruction, and Malone antegrade continence enema. Additional Medical Subject Headings terms used to augment the search included \"Treatment Outcome\" and \"Robotic Surgical Procedures.\"</p><p><strong>Results: </strong>Increasing usage of RALS has shown many benefits in perioperative and postoperative outcomes. In addition, there is growing evidence that robotic procedures in pediatric urology result in similar or better surgical outcomes when compared to the standard of care.</p><p><strong>Conclusions: </strong>RALS has shown considerable effectiveness in pediatric urologic procedures and may achieve surgical outcomes comparable to the standard approaches of open or laparoscopic surgery. However, larger case series and prospective randomized controlled trials are still necessary to validate the reported outcomes, in addition to cost analyses and studies on the surgical learning curve. We believe that the continuous evolution of robotic platforms will allow for enhanced care and quality of life for pediatric urology patients.</p>","PeriodicalId":47352,"journal":{"name":"Indian Journal of Urology","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f5/d2/IJU-39-107.PMC10249524.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9674215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison between neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio as predictors of mortality on Fournier's gangrene cases.","authors":"Soetojo Wirjopranoto","doi":"10.4103/iju.iju_256_22","DOIUrl":"10.4103/iju.iju_256_22","url":null,"abstract":"<p><strong>Introduction: </strong>Fournier's gangrene (FG) is an infection of the subcutaneous tissue and fascia that progresses quickly and leads to necrosis. It is more prevalent in male patients and immunocompromised individuals, such as those suffering from uncontrolled diabetes. It has a high mortality rate, which makes its early identification and clinical suspicion critical. This study aimed to compare two laboratory parameters, neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR), and to predict the mortality of FG in a tertiary care hospital.</p><p><strong>Methods: </strong>In a retrospective study, data was retrieved from medical records for the period from January 2014 to December 2020, of patients diagnosed with FG. Recorded data that is age, sex, comorbidities, mortality, and laboratory results (PLR and NLR) were used to assess determinants of survival.</p><p><strong>Results: </strong>There were 23 (17.04%) nonsurvivors among the 135 subjects studied. The mean age was 50.9 ± 14.9 years and men were 103 (83%) patients. Among the participants, diabetes mellitus was the most frequent comorbidity at 74 (54.81%) patients. NLR ≥8 was statistically significant (<i>P</i> = 0.013) for identifying mortality, while PLR >140 was not. In multivariate analysis, NLR ≥8 was found to be a reliable predictor of the FG mortality rate (adjusted odds ratio 12.062, confidence interval 95% 2.115-68.778, <i>P</i> = 0.005).</p><p><strong>Conclusion: </strong>NLR had prognosis predictive value for FG, whereas PLR did not.</p>","PeriodicalId":47352,"journal":{"name":"Indian Journal of Urology","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e7/99/IJU-39-121.PMC10249533.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10356446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of preoperative estrogen on complications after proximal hypospadias repair: A randomized controlled trial.","authors":"Akash Bihari Pati,&nbsp;Pritinanada Mishra,&nbsp;Santosh K Mahalik,&nbsp;Bikasha Bihary Tripathy,&nbsp;Manoj Kumar Mohanty","doi":"10.4103/iju.iju_387_22","DOIUrl":"10.4103/iju.iju_387_22","url":null,"abstract":"<p><strong>Introduction: </strong>Proximal hypospadias repair has many postoperative complications such as urethrocutaneous fistulae, wound dehiscence, and urethral stricture. The beneficial effect of estrogen to promote wound healing has been known. We designed a study to determine whether preoperative stimulation of tissue with estrogen can reduce the postoperative complications associated with wound healing in patients undergoing hypospadias repair.</p><p><strong>Methods: </strong>Patients with proximal hypospadias requiring two-stage repairs (chordee correction followed by urethral tubularization) were randomized to estrogen and control groups before the second stage of surgery. In the former, topical estrogen cream (0.5 mg of estriol) was applied to the ventral penis for a month, whereas normal saline gel was applied to the latter; the urethroplasty was carried out thereafter. Patients were followed up for complications.</p><p><strong>Results: </strong>There were 29 patients in the estrogen group and 31 in the placebo group after the exclusion criteria were met. There was no significant difference in the overall postoperative complications between the estrogen group (44.8%) and the placebo group (51.6%). The occurrence of urethrocutaneous fistula (37.9% vs. 51.6%) and dehiscence (41.4% vs. 45.2%) was not significantly different between the estrogen and placebo groups. Neourethral stricture occurred in four patients in the estrogen group, while none of the patients in the placebo group developed stricture.</p><p><strong>Conclusions: </strong>The preoperative application of topical estrogen cream to the ventral penis failed to demonstrate any significant effect on wound healing and complications.</p>","PeriodicalId":47352,"journal":{"name":"Indian Journal of Urology","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e0/bf/IJU-39-126.PMC10249528.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9975934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perioperative, oncological, and survival outcomes of robotic radical cystectomy with urinary diversion in females: A single-center retrospective observational study.","authors":"Varun V Agarwal,&nbsp;B Yuvaraja Thyavihally,&nbsp;Santosh Subhash Waigankar,&nbsp;Preetham Dev,&nbsp;Abhinav P Pednekar,&nbsp;Diptiman Roy,&nbsp;Nevitha Athikari,&nbsp;Meenal Hastak,&nbsp;Naresh Badlani,&nbsp;D Harshwardhan Pokharkar,&nbsp;Nagaraja Sekhar Ayyalasomayajula,&nbsp;Archan Khandekar,&nbsp;Ashish Asari","doi":"10.4103/iju.iju_179_21","DOIUrl":"10.4103/iju.iju_179_21","url":null,"abstract":"<p><strong>Introduction: </strong>Robot-assisted radical cystectomy (RARC) is a standrad approach for surgical management of bladder cancer. Currently, most literature on RARC is in men, possibly due to the higher incidence of bladder cancer in males. We reviewed the perioperative, oncological and survival outcomes in 41 women who underwent RARC by a single surgeon at a tertiary health-care center.</p><p><strong>Methods: </strong>Out of 225 RARC and urinary diversion procedures performed from 2012 to 2020, a retrospective analysis of 41 women was performed. Baseline demographic and perioperative details, oncological data, and survival were recorded and analyzed. Kaplan-Meir analysis was done for survival outcomes and prognostic factors were assessed by log rank test.</p><p><strong>Results: </strong>Thirty-eight patients underwent intracorporeal urinary diversion, while three underwent extracorporeal diversion. One patient underwent organ preserving cystectomy. Clavien-Dindo 30-day postoperative complications were Grade I in 8 (19.5%), Grade II in 4 (9.8%), and Grade IIIa in 3 (7.3%) patients with no mortality. During the median follow-up of 34 months (range: 6-87 months), 7 patients died of disease recurrence. Five-year survival was 74% (95% confidence interval [CI]: 59-82) and 35% (95% CI: 10-91) in transitional cell carcinoma (TCC) and non-TCC group, respectively, with <i>P</i> = 0.04. There was no mortality in Stages 0 and 1 disease. Five-year survival was 78% in Stage 2 and 41% in Stage 3 and 4.</p><p><strong>Conclusion: </strong>Our study demonstrates acceptable clinical, perioperative, and oncological outcomes of robotic radical cystectomy in females, thus highlighting its safety and feasibility.</p>","PeriodicalId":47352,"journal":{"name":"Indian Journal of Urology","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/97/ef/IJU-39-27.PMC9942226.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9335817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Growth and popularity of urology as a specialty among residents in India","authors":"Apul Goel, SandeepKumar Patel","doi":"10.4103/iju.iju_221_23","DOIUrl":"https://doi.org/10.4103/iju.iju_221_23","url":null,"abstract":"In India, to practice urology, a surgical resident is required to enter into a training program and acquire one of two equivalent degrees; Magister Chirurgiae (MCh) or Diplomate of National Board (DNB). Both government and privately run medical colleges/universities may be accredited to offer either of these two degrees. Some of the government run institutions, designated as Institute of National Importance (INI), can also award these degrees after admitting students to their training program through an entrance examination separate from other institutions. To register for urology training, a student who has completed a 3-year training program in general surgery, has to appear in an all India entrance examination called the National Eligibility-cum-Entrance Test Super Specialty (NEET-SS) conducted by the National Testing Agency. As there are a total of 4285 seats for pursuing residency in general surgery (including Master of Surgery [MS] and DNB Surgery),[1] more than 4285 students are eligible to appear in the entrance examination for surgical super-specialties (including urology) each year including some who may qualified in earlier years. While taking the NEET-SS exam, till 2021, all eligible students could opt to take the exam for upto two super-specialties. Furthermore, till 2021, the exam for admission to urology included questions primarily from the field of urology. Similarly, a student who appeared for neurosurgery had to answer questions based on the subject of neurosurgery. In 2022, however, the question paper pattern was changed, and now the entire examination, for all the super-specialities, tests the students knowledge of general surgery only. In India, urology as a specialty was first started in 1965 by the University of Madras.[2] Subsequent progress was slow and only a handful of departments offered urology training, mostly at the national institutes. Although robust data are lacking, by 2006, there were approximately 20–25 centers that awarded the MCh degree and around 10–12 centers offered DNB courses in urology.[3] Today, there are 96 institutes with M.Ch programmes in urology, including 53 government run and 43 privately run colleges. This translates into a total of 309 seats for MCh urology, 181 in the government and 128 in the privately run medical colleges. Besides, there are nine INIs with a total of 31-MCh seats. 70 centers offer a DNB in urology, with a total of 126 seats throughout the country. The number of available seats and their growth in the past 7 years (between 2016 and 2022) for some common surgical super-specialties is shown in Table 1. The largest increase, of 223 seats, is seen in the field of urology. Typically, the number of seats in a specialty reflects its popularity, mirroring the phenomenon of demand and supply. By that yardstick, urology has witnessed the maximum increase in the number of available seats.Table 1: Year-wise total number of seats (Magister Chirurgiae and Diplomate of National Board com","PeriodicalId":47352,"journal":{"name":"Indian Journal of Urology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135953168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Author Reply Re: Sharma G, Shah M, Ahluwalia P, Dasgupta P, Challacombe BJ, Bhandari M, <i>et al</i>. Perioperative outcomes following robot-assisted partial nephrectomy for complex renal masses: A Vattikuti Collective Quality Initiative database study. Indian J Urol 2022;38:288-95.","authors":"Gopal Sharma,&nbsp;Puneet Ahluwalia,&nbsp;Gagan Gautam","doi":"10.4103/iju.iju_393_22","DOIUrl":"10.4103/iju.iju_393_22","url":null,"abstract":"We read with great interest the “letter to the editor” on our article published in the October–December 2022 issue of the Indian Journal of Urology.[1] We would like to thank the authors for their kind comments and for showing interest in our study. In their “letter to the editor”, authors have reiterated the previously mentioned limitations of the Vattikuti Collective Quality Initiative (VCQI) database in the original study such as those related to hilar location, endophytic tumors, and surgeon factors.[1] The template used for VCQI robot-assisted partial nephrectomy (RAPN) database has been employed since 2014 without any update. Contemporarily, the database has multiple limitations which have been adequately highlighted in the present and previous studies.[2-4] Efforts are being made to update the database to the current standard of scientific reasoning.","PeriodicalId":47352,"journal":{"name":"Indian Journal of Urology","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/59/04/IJU-39-80.PMC9942227.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10773564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prosthetics in urology: Current status and future directions.","authors":"Abhilash Cheriyan","doi":"10.4103/iju.iju_90_22","DOIUrl":"10.4103/iju.iju_90_22","url":null,"abstract":"<p><p>The field of genitourinary prosthetics has evolved rapidly to become the standard of care for conditions such as incontinence and refractory erectile dysfunction. Its scope has expanded to encompass newer indications such as Peyronie's disease and gender-affirming surgeries. This review, based on the Urological Society of India's Best Essay Award 2022, aims to elaborate on the advances in the field of urological prosthetics in the past 20 years as well as to provide an insight into ongoing research and what one can expect to see in the next decade, particularly in the area of penile and testicular prosthetics as well as treatment of incontinence. A PubMed and patent search was performed to achieve these objectives. Future considerations include improving acceptance, reliability, making them more accessible for developing countries and improving training and education to improve outcomes.</p>","PeriodicalId":47352,"journal":{"name":"Indian Journal of Urology","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c6/68/IJU-39-12.PMC9942223.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10773567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}