{"title":"Comparison of outcomes after open versus robotic kidney transplantation: A systematic review and meta-analysis.","authors":"Kumar Madhavan, Rahul Jena, Priyank Bhargava, Aditya Pradhan, Mahendra Bhandari","doi":"10.4103/iju.iju_390_22","DOIUrl":"10.4103/iju.iju_390_22","url":null,"abstract":"<p><strong>Introduction: </strong>This meta-analysis compares the clinical outcomes of robot-assisted kidney transplant (RAKT) to open kidney transplant (OKT).</p><p><strong>Methods: </strong>A systematic search of Scopus and MEDLINE databases was carried out using a combination of keywords to identify studies comparing RAKT to OKT. Baseline characteristics and preoperative and postoperative data were collected along with data on the short- and long-term outcomes. The study was registered in PROSPERO and Assessing the Methodological Quality of Systematic Reviews and Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines were followed.</p><p><strong>Results: </strong>A total of 16 studies were included with a total of 2555 patients, of which 677 underwent RAKT and 1878 underwent OKT. This meta-analysis shows a significant benefit of RAKT over OKT in terms of less intra-operative blood loss, smaller incision length, less postoperative pain scores at 24 and 48 hours, and a lower incidence of surgical site infections (SSIs), especially in obese patients. In addition, the incidence of postoperative lymphoceles was lower in the RAKT group compared to the OKT group, although not statistically significant. There was no difference between the two groups in terms of short-term graft functional outcomes and overall survival. The number of deceased donor recipients undergoing RAKT was very small. At the time of reporting this meta-analysis, no randomized controlled trials (RCTs) had been published.</p><p><strong>Conclusion: </strong>This meta-analysis showed that RAKT is a safe and feasible alternative to OKT, especially in obese individuals. Further trials are needed to confirm the safety, efficacy, and cost-effectiveness of RAKT.</p>","PeriodicalId":47352,"journal":{"name":"Indian Journal of Urology","volume":"39 3","pages":"186-194"},"PeriodicalIF":1.1,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/24/a6/IJU-39-186.PMC10419774.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10350988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Re: Budukh AM, Thakur JS, Dora TK, Kadam PR, Bagal SS, Patel KK, <i>et al</i>. Overall survival of prostate cancer from Sangrur and Mansa cancer registries of Punjab state, India. Indian J Urol 2023;39:148.","authors":"Soumya Shivasis Pattnaik","doi":"10.4103/iju.iju_186_23","DOIUrl":"10.4103/iju.iju_186_23","url":null,"abstract":"","PeriodicalId":47352,"journal":{"name":"Indian Journal of Urology","volume":"39 3","pages":"252-253"},"PeriodicalIF":1.3,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/6f/e5/IJU-39-252.PMC10419767.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10052257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Medical conferences: Limitation or liberal escalation.","authors":"Rishi Nayyar","doi":"10.4103/iju.iju_173_23","DOIUrl":"10.4103/iju.iju_173_23","url":null,"abstract":"Conferences are an important and integral part of scientific networking and exchange of ideas, while simultaneously providing an opportunity to showcase scientific work and staying abreast with technology and trade. Of late, the number of medical conferences being held has increased exponentially, seemingly outgrowing their need and demand. Herd mentality seems to have engulfed the society from its highest echelons to its lowest levels, each organizing a multitude of conferences in various forms. But, as a responsible society, should we be concerned? We need to understand the needs of students, practicing urologists, teachers, institutions, and the society at large and how conferences may help fulfill these needs before we draw any conclusion about limiting or escalating the number of conferences. For each of these elements of the society, the ideal conference would vary not only in terms of numbers but also their nature, content, mode, and delivery. For a senior urologist, a conference every weekend is unlikely to be of any benefit professionally or otherwise, particularly when the same set of individuals are involved as the core group.","PeriodicalId":47352,"journal":{"name":"Indian Journal of Urology","volume":"39 3","pages":"179-180"},"PeriodicalIF":1.1,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/cf/45/IJU-39-179.PMC10419773.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10052259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Socio-economic, education, and insurance-related factors associated with the treatment completion rates in patients with nonmetastatic urinary bladder cancer: A Retrospective cohort study.","authors":"Gorrepati Rohith, Abhay Singh Gaur, Prasant Nayak, Swarnendu Mandal, Manoj K Das, Santosh Kumaraswamy, Vivek Tarigopula, Sambit Tripathy","doi":"10.4103/iju.iju_116_23","DOIUrl":"10.4103/iju.iju_116_23","url":null,"abstract":"<p><strong>Introduction: </strong>Among urological malignancies, the diagnosis and treatment of urinary bladder cancer (UBC) incurs the highest cost per patient. Our objective was to broaden the current understanding of how demographic, socioeconomic, education, and insurance-related factors influence UBC management.</p><p><strong>Methods: </strong>Between January 2017 and December 2019, all patients with nonmetastatic bladder cancer were included. The demographic, treatment, and follow-up details were retrieved from a prospectively maintained database, and the Modified Kuppuswamy Index was used to evaluate the patients' socioeconomic level. Patients were divided into the completed treatment group, or the incomplete treatment group based on adherence to the initially intended treatment plan. Patients who presented with benign disease or metastases were not included.</p><p><strong>Results: </strong>Eighty-nine patients did not complete the initially intended course of treatment out of 132 patients who needed additional management after the initial transurethral resection. Comparable risk factors and demographic profiles existed in both groups. Patients with intermediate-risk disease are more likely to fail to adhere to the initial intended treatment (odds ratio [OR] = 0.09; 95% confidence interval [CI]: 0.02-0.30). On logistic regression analysis, upper socioeconomic status (OR = 6.8; 95% CI: 0.35-132.1) patients and patients with higher educational status of graduation or above (OR = 3.62; 95% CI: 0.75-17.43) had higher chances of treatment completion. Education status significantly impacted treatment completion on multivariate analysis (<i>P</i> = 0.01). Patients who utilized employer-funded insurance had better treatment compliance (OR = 4.1; 95% CI: 0.90-18.7). The compliance was unaffected by smoking, occupation, or other demographic factors.</p><p><strong>Conclusion: </strong>Patients with low economic status, low levels of education, and who need adjuvant intravesical therapy had considerably greater treatment dropout rates.</p>","PeriodicalId":47352,"journal":{"name":"Indian Journal of Urology","volume":"39 3","pages":"228-235"},"PeriodicalIF":1.1,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/31/c7/IJU-39-228.PMC10419770.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10052255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Author Reply Re: Wirjopranoto S. Comparison between neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio as predictors of mortality on Fournier's gangrene cases. Indian J Urol 2023;39:121-5.","authors":"Soetojo Wirjopranoto","doi":"10.4103/iju.iju_183_23","DOIUrl":"10.4103/iju.iju_183_23","url":null,"abstract":"","PeriodicalId":47352,"journal":{"name":"Indian Journal of Urology","volume":"39 3","pages":"255"},"PeriodicalIF":1.3,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/71/b1/IJU-39-255.PMC10419766.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10052256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Krishnendu Maiti, Swadeep Kumar Srivastava, Dilip Kumar Pal
{"title":"Low-intensity extracorporeal shockwave therapy for Peyronie's disease: An Indian experience.","authors":"Krishnendu Maiti, Swadeep Kumar Srivastava, Dilip Kumar Pal","doi":"10.4103/iju.iju_22_23","DOIUrl":"10.4103/iju.iju_22_23","url":null,"abstract":"<p><strong>Introduction: </strong>Efficacy of low-intensity extracorporeal shockwave therapy (LiESWT) in Peyronie's disease (PD) has not been studied in an Indian population. Here, we studied the effect of LiESWT in Indian PD patients.</p><p><strong>Methods: </strong>This prospective study was conducted on 25 patients who completed weekly sessions of LiESWT for 6 weeks with a follow-up of 6 months. Patients were evaluated using International Index of Erectile Function (IIEF)-5 questionnaire for erectile dysfunction and visual analog scale for pain. Baseline and follow-up examinations included measurement of plaque size and curvature. The primary outcome was to assess remission of pain and reduction of plaque size along with improvement of penile curvature and erectile function as the secondary outcome.</p><p><strong>Results: </strong>Primary goal of pain reduction and ≥50% reduction of plaque size was achieved in 64% and 20% of patients, respectively. Improvement in vaginal penetration during sexual intercourse and IIEF-5 score increase of ≥3 was achieved 20% and 36% cases, respectively. The mean reduction of penile curvature was more with plaque calcification (PC), but the difference was not statistically significant (<i>P</i> = 0.26). The difference in mean visual analog scale reduction was more in noncalcified plaque (<i>P</i> = 0.002). The mean reduction of plaque size in patients with PC was significant (<i>P</i> = 0.03).</p><p><strong>Conclusions: </strong>Shockwave therapy is a probable alternative treatment option. A significant improvement was observed in pain and plaque size in patients treated by LiESWT. The presence of PC may affect the outcome of LiESWT in PD.</p>","PeriodicalId":47352,"journal":{"name":"Indian Journal of Urology","volume":"39 3","pages":"209-215"},"PeriodicalIF":1.1,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c1/b9/IJU-39-209.PMC10419780.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10052253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinicoradiological parameters predicting operative difficulty in laparoscopic partial nephrectomy for renal tumors.","authors":"Faisal Masood Pirzada, Rajeev Sood, Anil Taneja, Umesh Sharma, Hemant Kumar Goel, Sumit Gahlawat","doi":"10.4103/iju.iju_384_22","DOIUrl":"10.4103/iju.iju_384_22","url":null,"abstract":"<p><strong>Introduction: </strong>The number of renal tumors amenable to laparoscopic surgery is rising, both, due early detection by improved imaging techniques and due to progressive improvements in minimal access surgery. Conversion to open surgery, which is a significant event, can be minimized by proper case selection. We assessed the pre-operative factors that can predict the operative difficulty and can help in case selection, thus avoiding complications and reducing the chances of conversion to open.</p><p><strong>Methods: </strong>One hundred and sixteen patients (73 males and 43 females) with the mean age of 50.78 ± 14.2 years, meeting the inclusion criteria underwent transperitoneal laparoscopic partial nephrectomy (LPN). Various clinical, anthropometric, radiological, and pathological parameters were recorded. Intraoperative difficulty was assessed and graded on a scale of 1 (easiest) to 4 (most difficult or open conversion) by an independent observer to calculate the difficulty score, which along with the other parameters of operative difficulty, was used to calculate the difficulty scale. Significant parameters on the univariate analysis, were subjected to a multivariate analysis, to find parameters that can predict the operative difficulty.</p><p><strong>Results: </strong>The mean age was 52 ± 14.29 years, mean size was 4 ± 1.04 cm, male:female ratio was 1.6:1, most of the tumors were exophytic (60%) and anteriorly located (62%) and had a mean perinephric fat surface density (PnFSD) of 6446.026 ± 2244 surface density pixel units (SDPU). On the univariate analysis, age >60 years, Eastern Cooperative Oncology Group performance score >1, presence of perinephric fat stranding, increased PnFSD (>10,000 SDPU), large tumor size (>4 cm), hilar/posterior location, endophytic tumors and higher clinical stage were significantly associated with intraoperative difficulty. However, on the multivariate analysis, no single factor could independently predict intraoperative difficulty in LPN for Renal tumors.</p><p><strong>Conclusion: </strong>It is difficult to predict the intra-operative difficulty during LPN. Feasibility of LPN should be based on multiple factors rather than a single factor.</p>","PeriodicalId":47352,"journal":{"name":"Indian Journal of Urology","volume":"39 3","pages":"216-222"},"PeriodicalIF":1.1,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/bb/29/IJU-39-216.PMC10419771.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10052264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Atul Madhukar Budukh, Jarnail S Thakur, Tapas Kumar Dora, Prithviraj R Kadam, Sonali S Bagal, Kamalesh Kumar Patel, Alok K Goel, Sankalp M Sancheti, Ashish R Gulia, Pankaj P Chaturvedi, Rajesh P Dikshit, Rajendra A Badwe
{"title":"Author reply re: Budukh AM, Thakur JS, Dora TK, Kadam PR, Bagal SS, Patel KK, <i>et al</i>. Overall survival of prostate cancer from Sangrur and Mansa cancer registries of Punjab state, India. Indian J Urol 2023;39:148.","authors":"Atul Madhukar Budukh, Jarnail S Thakur, Tapas Kumar Dora, Prithviraj R Kadam, Sonali S Bagal, Kamalesh Kumar Patel, Alok K Goel, Sankalp M Sancheti, Ashish R Gulia, Pankaj P Chaturvedi, Rajesh P Dikshit, Rajendra A Badwe","doi":"10.4103/iju.iju_208_23","DOIUrl":"10.4103/iju.iju_208_23","url":null,"abstract":"","PeriodicalId":47352,"journal":{"name":"Indian Journal of Urology","volume":"39 3","pages":"253-254"},"PeriodicalIF":1.3,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f1/b4/IJU-39-253.PMC10419781.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10052249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Upper moiety vascular ureteropelvic junction obstruction in an incomplete duplex kidney: A variant of the Fraley's syndrome?","authors":"Somanath Karmungikar, Siddharth Yadav, Ankit Goel","doi":"10.4103/iju.iju_30_23","DOIUrl":"10.4103/iju.iju_30_23","url":null,"abstract":"<p><p>Although duplication of the collecting system is fairly common, ureteropelvic junction obstruction of the upper moiety in a patient with duplex system is rare, more so if the obstruction is extrinsic and vascular. Herein, we report a case of obstruction of the upper moiety infundibulum by a crossing vein, in a patient with partially duplex system who presented with flank pain and focal hydronephrosis of the superior calyx, a clinical presentation similar to that of Fraley's syndrome. The infundibulum was transected and transposed anterior to the crossing vessel.</p>","PeriodicalId":47352,"journal":{"name":"Indian Journal of Urology","volume":"39 3","pages":"245-248"},"PeriodicalIF":1.1,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c2/ac/IJU-39-245.PMC10419786.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10052258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}