Indian Journal of Urology最新文献_第8页

Is rucaparib the definite direction for metastatic prostate cancer? – TRITON3 results decoded 鲁卡帕尼是治疗转移性前列腺癌的明确方向吗？- TRITON3 结果解码

IF 1.1

Indian Journal of Urology Pub Date : 2023-12-29 DOI: 10.4103/iju.iju_373_23

Abhijit S. Shah

引用次数: 0

Round up 综述

IF 1.1

Indian Journal of Urology Pub Date : 2023-12-29 DOI: 10.4103/iju.iju_472_23

S. Mandal

引用次数: 0

Evaluation of a novel augmented reality educational tool and its effects on patient experience: A randomized controlled trial 评估新型增强现实教育工具及其对患者体验的影响：随机对照试验

IF 1.1

Indian Journal of Urology Pub Date : 2023-12-29 DOI: 10.4103/iju.iju_191_23

Caroline A. Miller, Rachel A. Locke, Hailey W. Holck, Holt J. Evans, Tiag P. Bhamber, Alexander L. Sinks, Lila G. McGrath, Danielle M. Boselli, Peter E. Clark, Ornob P. Roy

{"title":"Evaluation of a novel augmented reality educational tool and its effects on patient experience: A randomized controlled trial","authors":"Caroline A. Miller, Rachel A. Locke, Hailey W. Holck, Holt J. Evans, Tiag P. Bhamber, Alexander L. Sinks, Lila G. McGrath, Danielle M. Boselli, Peter E. Clark, Ornob P. Roy","doi":"10.4103/iju.iju_191_23","DOIUrl":"https://doi.org/10.4103/iju.iju_191_23","url":null,"abstract":"Patient education is an essential element of the treatment pathway. Augmented reality (AR), with disease simulations and three-dimensional visuals, offers a developing approach to patient education. We aim to determine whether this tool can increase patient understanding of their disease and post-visit satisfaction in comparison to current standard of care (SOC) educational practices in a randomized control study. Our single-site study consisted of 100 patients with initial diagnoses of kidney masses or stones randomly enrolled in the AR or SOC arm. In the AR arm, a physician used AR software on a tablet to educate the patient. SOC patients were educated through traditional discussion, imaging, and hand-drawn illustrations. Participants completed pre- and post-physician encounter surveys adapted from the Press Ganey® patient questionnaire to assess understanding and satisfaction. Their responses were evaluated in the Readability Studio® and analyzed to quantify rates of improvement in self-reported understanding and satisfaction scores. There was no significant difference in participant education level (P = 0.828) or visit length (27.6 vs. 25.0 min, P = 0.065) between cohorts. Our data indicate that the rate of change in pre- to post-visit self-reported understanding was similar in each arm (P ≥ 0.106 for all responses). The AR arm, however, had significantly higher patient satisfaction scores concerning the educational effectiveness and understanding of images used during the consultation (P < 0.05). While AR did not significantly increase self-reported patient understanding of their disease compared to SOC, this study suggests AR as a potential avenue to increase patient satisfaction with educational tools used during consultations.","PeriodicalId":47352,"journal":{"name":"Indian Journal of Urology","volume":"19 1","pages":""},"PeriodicalIF":1.1,"publicationDate":"2023-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139147909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Human epidermal growth factor receptor 2/neu expression in urothelial carcinomas 尿路上皮癌中人类表皮生长因子受体 2/neu 的表达

IF 1.1

Indian Journal of Urology Pub Date : 2023-12-29 DOI: 10.4103/iju.iju_287_23

A. Soudamini, A. Nalwa, G. Choudhary, J. Bharti, M. Rao, P. Elhence, Himanshu Pandey, A. Goel

{"title":"Human epidermal growth factor receptor 2/neu expression in urothelial carcinomas","authors":"A. Soudamini, A. Nalwa, G. Choudhary, J. Bharti, M. Rao, P. Elhence, Himanshu Pandey, A. Goel","doi":"10.4103/iju.iju_287_23","DOIUrl":"https://doi.org/10.4103/iju.iju_287_23","url":null,"abstract":"Urothelial carcinomas of the bladder are more common in males, making them the sixth-most common cancer in men and the tenth-most common cancer overall, worldwide. Current guidelines do not recommend routine testing for human epidermal growth factor receptor (HER2/neu) expression on the biopsy specimens of patients with urothelial carcinoma. This study was aimed at determining the expression pattern of HER2/neu and its usefulness in muscle-invasive and nonmuscle-invasive urothelial carcinoma. HER2/neu expression was assessed in 89 specimens of urothelial cancer by immunohistochemistry (IHC), and equivocal cases were subjected to fluorescent in situ hybridization (FISH). On IHC for HER2/neu, 17.9% (7/39) of the muscle-invasive bladder cancers (MIBCs) showed a 3+ expression, whereas 22% (11/50) of the non-muscle invasive cancers were positive with a score of 3+. A significant correlation between HER2/neu status and muscle invasion could not be established in the current study (P = 0.74, Fisher’s exact test). Three cases of muscle-invasive (7.7%) and 2 cases (4%) among nonmuscle invasive cancers showed equivocal expression. All the cases with equivocal (2+) expression on IHC were subjected to FISH and none showed gene amplification on hybridization and were considered as negative. Overexpression of HER-2/neu was seen in 17.9% of MIBCs and 22% of non-MIBCs. There are no norms for routine testing of HER2/neu expression in the biopsy specimens of urothelial carcinoma. There is an unmet need to establish guidelines for HER2/neu scoring, similar to that for breast and gastric cancers, to determine the proportion of positive cases and help in identification of those who may benefit from targeted therapies.","PeriodicalId":47352,"journal":{"name":"Indian Journal of Urology","volume":" 26","pages":""},"PeriodicalIF":1.1,"publicationDate":"2023-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139143835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fifteen-year outcomes of the ProtecT trial: Should patients be "protected" from radical treatments? ProtecT 试验的 15 年结果：是否应 "保护 "患者免于接受根治性治疗？

IF 1.1

Indian Journal of Urology Pub Date : 2023-10-01 Epub Date: 2023-09-29 DOI: 10.4103/iju.iju_271_23

Nisanth Puliyath

引用次数: 0

Talazoparib plus enzalutamide for metastatic castration-resistant prostate cancer: TALAPRO-2 trial. 他唑帕尼联合恩杂鲁胺治疗转移性耐受性前列腺癌：TALAPRO-2试验。

IF 1.1

Indian Journal of Urology Pub Date : 2023-10-01 Epub Date: 2023-09-29 DOI: 10.4103/iju.iju_307_23

Prashant Gupta

引用次数: 0

Triplet combination in metastatic renal cell carcinoma. 转移性肾细胞癌的三联疗法

IF 1.1

Indian Journal of Urology Pub Date : 2023-10-01 Epub Date: 2023-09-29 DOI: 10.4103/iju.iju_192_23

P Jithesh

引用次数: 0

Post hoc analysis of CheckMate 274 trial for programmed death-ligand 1 expression and outcome. 对CheckMate 274试验中程序性死亡配体1的表达和结果进行事后分析。

IF 1.1

Indian Journal of Urology Pub Date : 2023-10-01 Epub Date: 2023-09-29 DOI: 10.4103/iju.iju_172_23

Deepak Prakash Bhirud

引用次数: 0

Quality: The eternal goal of scientific publishing 质量：科学出版的永恒目标

IF 1.1

Indian Journal of Urology Pub Date : 2023-09-29 DOI: 10.4103/iju.iju_457_23

Rajeev Kumar

引用次数: 0

Comparison of outcomes after open versus robotic kidney transplantation: A systematic review and meta-analysis. 开放式与机器人肾移植术后结果的比较：一项系统综述和荟萃分析。

IF 1.1

Indian Journal of Urology Pub Date : 2023-07-01 Epub Date: 2023-06-30 DOI: 10.4103/iju.iju_390_22

Kumar Madhavan, Rahul Jena, Priyank Bhargava, Aditya Pradhan, Mahendra Bhandari

{"title":"Comparison of outcomes after open versus robotic kidney transplantation: A systematic review and meta-analysis.","authors":"Kumar Madhavan, Rahul Jena, Priyank Bhargava, Aditya Pradhan, Mahendra Bhandari","doi":"10.4103/iju.iju_390_22","DOIUrl":"10.4103/iju.iju_390_22","url":null,"abstract":"Introduction: This meta-analysis compares the clinical outcomes of robot-assisted kidney transplant (RAKT) to open kidney transplant (OKT).Methods: A systematic search of Scopus and MEDLINE databases was carried out using a combination of keywords to identify studies comparing RAKT to OKT. Baseline characteristics and preoperative and postoperative data were collected along with data on the short- and long-term outcomes. The study was registered in PROSPERO and Assessing the Methodological Quality of Systematic Reviews and Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines were followed.Results: A total of 16 studies were included with a total of 2555 patients, of which 677 underwent RAKT and 1878 underwent OKT. This meta-analysis shows a significant benefit of RAKT over OKT in terms of less intra-operative blood loss, smaller incision length, less postoperative pain scores at 24 and 48 hours, and a lower incidence of surgical site infections (SSIs), especially in obese patients. In addition, the incidence of postoperative lymphoceles was lower in the RAKT group compared to the OKT group, although not statistically significant. There was no difference between the two groups in terms of short-term graft functional outcomes and overall survival. The number of deceased donor recipients undergoing RAKT was very small. At the time of reporting this meta-analysis, no randomized controlled trials (RCTs) had been published.Conclusion: This meta-analysis showed that RAKT is a safe and feasible alternative to OKT, especially in obese individuals. Further trials are needed to confirm the safety, efficacy, and cost-effectiveness of RAKT.","PeriodicalId":47352,"journal":{"name":"Indian Journal of Urology","volume":"39 3","pages":"186-194"},"PeriodicalIF":1.1,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/24/a6/IJU-39-186.PMC10419774.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10350988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2