Fanar Turki Al-Jadwaa, Nadia Modhafer Ahmed Alshakir, Saif Nadhim Hassoon, Nawal Atiya Al-Sabawi
{"title":"Influence of Various Chelating Irrigating Solutions and Protocols on the Micro-hardness and Surface Roughness of Root Dentin.","authors":"Fanar Turki Al-Jadwaa, Nadia Modhafer Ahmed Alshakir, Saif Nadhim Hassoon, Nawal Atiya Al-Sabawi","doi":"10.4103/jispcd.jispcd_7_25","DOIUrl":"10.4103/jispcd.jispcd_7_25","url":null,"abstract":"<p><strong>Aim: </strong>Effective irrigants and chemo-mechanical debridement are critical for successful endodontic therapy. However, use of irrigating solutions can significantly alter the physical properties of root canal dentin, particularly its micro-hardness (MH) and surface roughness (SR). This study evaluated and compared the effects of three final chelating irrigants-0.5% chitosan nanoparticle solution (CNPs), 17% ethylenediaminetetraacetic acid (EDTA), and 10% citric acid (CA)-with and without ultrasonic (US) activation on the MH and SR of radicular dentin, aiming for informed clinical endodontic practices.</p><p><strong>Materials and methods: </strong>Forty-nine extracted mandibular premolars were decoronated, instrumented, longitudinally sectioned, and divided into 98 root halves. These were randomly assigned to two main groups for MH and SR testing and further subdivided (<i>n</i> = 7 per subgroup) based on the irrigant type and protocol: CNPs, CNPs + US, EDTA, EDTA + US, CA, CA + US, and distilled water (control). After 180-s immersion at 37°C, the MH was measured using a Vickers MH tester, while the SR was assessed using an SR tester. Statistical analyses were conducted using one-way analysis of variance with Tukey's <i>post hoc</i> test (<i>α</i> = 0.05).</p><p><strong>Results: </strong>EDTA and EDTA + US groups showed the most significant MH reduction across all root regions (coronal, middle, and apical), followed by CA and CA + US groups (<i>P</i> < 0.05). In contrast, CNPs and CNPs + US groups showed a significant increase in the MH compared to the control group (<i>P</i> < 0.05). Regarding SR, EDTA and EDTA + US produced the highest roughness values, while CNPs and CNPs + US treatment induced minimal SR changes relative to the control group.</p><p><strong>Conclusion: </strong>CNPs demonstrated superior performance by increasing dentin MH and minimizing SR alterations, suggesting it is a promising, bio-compatible alternative to conventional chelating agents like EDTA for endodontic irrigation.</p>","PeriodicalId":47247,"journal":{"name":"Journal of International Society of Preventive and Community Dentistry","volume":"15 3","pages":"275-283"},"PeriodicalIF":2.1,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12364412/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Manjiri Bhate, Ravindra K Jain, Arthi Balasubramaniam
{"title":"Effectiveness of Clear Aligner Therapy in Maxillary Molar Distalization for Class II Malocclusion: A Systematic Review of Clinical Studies.","authors":"Manjiri Bhate, Ravindra K Jain, Arthi Balasubramaniam","doi":"10.4103/jispcd.jispcd_59_24","DOIUrl":"10.4103/jispcd.jispcd_59_24","url":null,"abstract":"<p><strong>Aim: </strong>Addressing skeletal Class II (CII) malocclusion often involves molar distal movement (Dx). While traditional methods like headgear face challenges related to patient compliance, clear aligner therapy (CAT) is considered an appealing alternative, although its effectiveness in molar Dx is an ongoing study area. This systematic review (SR) seeks to review the recent studies on the efficacy of CAT for effecting molar Dx. The aim of this SR was to assess the effectiveness of CAT in achieving molar Dxs in individuals with sagittal CII malocclusion.</p><p><strong>Materials and methods: </strong>A comprehensive search in five electronic databases (Scopus, PubMed, Google Scholar, Cochrane, and Web of Science) for relevant articles till December 2023 was performed. The population, intervention, comparision, outcome and study design criteria included subjects with CII malocclusion intervened with CAT, the control was no treatment or fixed appliance therapy using traditional methods of molar distalization, and the outcomes assessed were molar Dx, achieved vs. predicted movements, molar tipping, and rotation. Only prospective trials, retrospective studies, randomized controlled trials (RCTs), and controlled clinical trials were included. The principal measure of Dx was millimeters. The risk of bias (ROB) assessment of the included studies was conducted using the Newcastle-Ottawa scale and ROBINS-I tool. Preferred reporting items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines were adopted for data reporting and synthesis. The SR was registered in the PROSPERO database (registration number CRD42024531205).</p><p><strong>Results: </strong>Out of 547 studies identified, 11 papers were included in the present SR. Eight of them were retrospective, and three were prospective studies. The sample size ranged from a minimum of seven to 49 patients. A total of 278 patients were assessed in all the studies. Invisalign<sup>®</sup> system CA was used in all studies. Five studies reported predicted vs. achieved tooth movements. Two studies reported the use of attachments, and one study reported the use of microimplants for preventing anchorage loss along with Class I elastics. Dx ranged from 0.67 ± 0.5 mm to 2.54 ± 0.12 mm. When compared to the predicted Dx, the achieved Dx for M6 was 36.48-75.5%; for M7, it was 41.94-72.2%, and the accuracy of derotation of molars was 62.7-77.5%. Quantitative analysis could not be performed owing to the heterogeneity in the included studies. Six included studies had a low ROB, and two of them had a moderate ROB. Three studies were ranked low quality on the Newcastle-Ottawa scale. The strength of evidence for the included studies was judged as moderate on assessment with the Agency for Healthcare Research and Quality criteria.</p><p><strong>Conclusion: </strong>The available moderate-quality evidence suggests that CAT can achieve molar Dx up to 2 mm with good accuracy. However, the included studies wer","PeriodicalId":47247,"journal":{"name":"Journal of International Society of Preventive and Community Dentistry","volume":"15 3","pages":"222-233"},"PeriodicalIF":2.1,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12364402/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144974006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Awareness of Oral Health Complications in Type 2 Diabetic Patients in Ajman, UAE: A Cross-Sectional Study.","authors":"Haydy Nassar, Radhika Taroor, Jayakumary Muttappallymyalil","doi":"10.4103/jispcd.jispcd_77_24","DOIUrl":"10.4103/jispcd.jispcd_77_24","url":null,"abstract":"<p><strong>Aim: </strong>Type 2 diabetes mellitus (T2DM) is linked to several oral complications, yet patient awareness of this association remains suboptimal, particularly in culturally and demographically diverse populations like the United Arab Emirates (UAE). The present study aimed to assess awareness of oral health implications among T2DM patients in Ajman, UAE, and to identify predictors of good awareness.</p><p><strong>Materials and methods: </strong>A cross-sectional study was conducted among 306 self-reported T2DM patients at a tertiary hospital. A validated, structured questionnaire assessed awareness across 12 oral health indicators. Descriptive and inferential statistics were used, with logistic regression to identify predictors of good awareness (score ≥6/12).</p><p><strong>Results: </strong>While 83.7% of participants acknowledged a general oral health impact of diabetes, awareness of specific complications was low, particularly regarding caries risk (24%) and effects on glycemic control (23%). Predictors of good awareness included higher education (AOR: 2.2, 95% CI: 1-4.6), T2DM duration ≥10 years (AOR: 3.3, 95% CI: 1.6-7.0), recent dental visits (AOR: 2.92, 95% CI: 1.2-7.0), and use of internet resources (AOR: 7.87, 95% CI: 1.3-46.4). Receiving education from healthcare providers was not significantly associated with improved awareness.</p><p><strong>Conclusion: </strong>Despite high general awareness, knowledge of specific oral health complications remains inadequate. The findings highlight the need for targeted, culturally contextualized educational interventions and the integration of oral health education into diabetes care protocols in the UAE and similar settings.</p>","PeriodicalId":47247,"journal":{"name":"Journal of International Society of Preventive and Community Dentistry","volume":"15 3","pages":"284-295"},"PeriodicalIF":2.1,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12364389/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144974015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Role of Poly Vinyl Pyrrolidone Iodine (PVP-I) in Preventing Cross-Infection during Dental Procedures: A Systematic Review in the COVID-19 Context.","authors":"Vania Jovita Gunawan, Fitrina Rachmadanty Siregar, Agatha Ravi Vidiasratri, Lisdrianto Hanindriyo","doi":"10.4103/jispcd.jispcd_78_24","DOIUrl":"10.4103/jispcd.jispcd_78_24","url":null,"abstract":"<p><strong>Aim: </strong>As the dental community navigates the challenges posed by the coronavirus disease 2019 (COVID-19) pandemic, mitigating the risk of viral cross-transmission among dentists and dental clinic operators remains paramount. Polyvinyl pyrrolidone iodine (PVP-I) has emerged as a promising agent in reducing the chance of cross-transmission, primarily through its broad-spectrum antiseptic properties and ability to kill viruses rapidly. This study aimed to explore the role of PVP-I in preventing cross-infection of severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) and assess its effectiveness as a prophylaxis before dental treatment.</p><p><strong>Materials and methods: </strong>A comprehensive search of multiple databases, including Science Direct, PubMed, Sage Journal, Cochrane, and Wiley Online Library, was conducted following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. The study selection process utilized the Patient, Intervention, Comparison, Outcome, and Study Design framework (P: SARS-CoV-2 positive individuals, I: PVP-I mouthwash, C: various PVP-I concentrations, O: virucidal effect, S: randomized-controlled trials and clinical trials). Titles and abstracts were screened for relevance, and full-text articles were assessed for eligibility based on predefined inclusion and exclusion criteria. The risk of bias was assessed using the Cochrane Risk of Bias Tool version 2 for randomized controlled trials and Toxicological Data Reliability Assessment Tool for <i>in vitro</i> studies. A total of 11 articles (seven <i>in vitro</i> and four <i>in vivo</i>) were included in the systematic review.</p><p><strong>Results: </strong>Our findings suggest that PVP-I exhibits superior antiseptic properties compared to other agents, with gargling using PVP-I solutions of 0.2% and 0.5% demonstrating significant efficacy in reducing viral load in saliva. Notably, PVP-I showed rapid virucidal action, effectively reducing SARS-CoV-2 viral particles and potentially lowering the risk of cross-infection during dental procedures. However, despite these promising results in viral reduction, the evidence remains insufficient to definitively recommend PVP-I as a routine clinical prophylaxis for preventing cross-infection in dental care settings during the COVID-19 pandemic. Further large-scale clinical trials are necessary to establish its widespread use.</p><p><strong>Conclusion: </strong>This systematic review highlights the potential of PVP-I as a critical antiseptic in dental settings to mitigate the risk of SARS-CoV-2 transmission. The rapid and significant reduction in viral load suggests that PVP-I could play a pivotal role in infection control protocols. Nonetheless, further robust clinical trials are essential to confirm its efficacy and guide its adoption in routine dental care practices.</p>","PeriodicalId":47247,"journal":{"name":"Journal of International Society of Preventive and Community Dentistry","volume":"15 3","pages":"197-210"},"PeriodicalIF":2.1,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12364388/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prevalence and Severity of Dental Caries Among Schoolchildren in Libya: A Systematic Review and Meta-Analysis.","authors":"Farida Abdunabi, Mawlood Kowash, Amar Khamis, Moosa Abuzayeda","doi":"10.4103/jispcd.jispcd_5_25","DOIUrl":"10.4103/jispcd.jispcd_5_25","url":null,"abstract":"<p><strong>Aim: </strong>Dental caries remains a significant public health burden among children in Libya, yet national-level epidemiological data are fragmented and inconsistent. This systematic review and meta-analysis aim to provide a comprehensive estimate of caries prevalence and severity among Libyan school children.</p><p><strong>Materials and methods: </strong>A systematic search of four electronic databases (PubMed, Scopus, Cochrane Library, and Google Scholar) was conducted for studies published between January 1990 and June 2024. Inclusion criteria targeted observational studies reporting Decayed, Missing, Filled Teeth (DMFT) scores or prevalence of caries among children aged 5-15 years in Libya. Data were synthesized using a random-effects model. Heterogeneity was assessed using <i>I</i>² and Cochran's <i>Q</i>-statistic. Publication bias was evaluated using funnel plots and Egger's regression test.</p><p><strong>Results: </strong>Seventeen studies were included, encompassing a pooled sample of 7149 children for DMFT and 7079 for prevalence. The overall mean DMFT was 2.577 (95% confidence interval [CI]: 2.533-2.620), and the pooled prevalence of caries in permanent teeth was 64.7% (95% CI: 63.9%-65.4%). Substantial heterogeneity was observed (<i>I</i> <sup>2</sup> > 99% for both outcomes, <i>P</i> < 0.001), and publication bias was confirmed by Egger's test (<i>P</i> = 0.001-0.003). Most studies originated from Benghazi, with limited data from other regions.</p><p><strong>Conclusions: </strong>Libyan children exhibit a high burden of dental caries, with significant geographic and methodological variability. These findings emphasize the urgent need for comprehensive preventive programs, school-based oral healthcare initiatives, and improved data collection strategies across all Libyan regions.</p>","PeriodicalId":47247,"journal":{"name":"Journal of International Society of Preventive and Community Dentistry","volume":"15 3","pages":"211-221"},"PeriodicalIF":2.1,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12364407/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144974008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alessandro Marchesi, Andrea Sardella, Shahnawaz Khijmatgar
{"title":"Depression and Anxiety as Predictors of Pain and Sensory Thresholds in Adults with and Without Temporomandibular Disorder: A Case-Control Study.","authors":"Alessandro Marchesi, Andrea Sardella, Shahnawaz Khijmatgar","doi":"10.4103/jispcd.jispcd_236_24","DOIUrl":"10.4103/jispcd.jispcd_236_24","url":null,"abstract":"<p><strong>Aim: </strong>Temporomandibular disorders (TMDs) are often associated with psychological distress and altered pain perception. However, the relationship between depression, anxiety, and sensory/pain thresholds in TMD remains underexplored. The present study aimed to assess the association of depression and anxiety with sensory and pain thresholds in adults with and without TMD using standardized electrical stimulation.</p><p><strong>Materials and methods: </strong>This observational case-control study included 56 adults with TMD and 56 matched healthy controls. Psychological distress was evaluated using the SCL-90-R questionnaire. Sensory and pain thresholds were assessed via electrical stimulation of the dental pulp. The sensory threshold was the minimum intensity of a stimulus, and pain threshold is the minimum intensity of a stimulus that triggers the perception of pain. Statistical analyses included Mann-Whitney U, Kruskal-Wallis, Spearman correlation, and multivariate logistic regression, adjusted for age and gender.</p><p><strong>Results: </strong>TMD subjects demonstrated significantly higher depression and anxiety scores than controls (<i>P</i> < 0.01). Pain thresholds were negatively correlated with depression and anxiety in both groups (<i>r</i> ≈ -0.63 to -0.66, <i>P</i> < 0.001), while anxiety correlated with lower sensory thresholds in TMD subjects only (<i>r</i> = -0.37, <i>P</i> < 0.01). Multivariate analysis revealed that a low pain threshold was independently associated with moderate/severe depression (OR = 4.38; 95% CI: 1.13-17.04), while a low sensory threshold was linked with moderate/severe anxiety, TMD status, female gender, and older age.</p><p><strong>Conclusion: </strong>Depression is independently associated with reduced pain thresholds in both TMD and healthy subjects. Anxiety is specifically linked to sensory threshold reduction in TMD patients. These findings underscore the need to integrate psychological assessment in chronic orofacial pain management.</p>","PeriodicalId":47247,"journal":{"name":"Journal of International Society of Preventive and Community Dentistry","volume":"15 3","pages":"257-264"},"PeriodicalIF":2.1,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12364403/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Adopting a Comprehensive Approach to Ensure Effective Delivery of Oral Healthcare Services among Elderly.","authors":"Saurabh RamBihariLal Shrivastava, Prateek Sudhakar Bobhate, Bayu Fajar Pratama, Vaishnavi Himanshu Mishra","doi":"10.4103/jispcd.jispcd_28_25","DOIUrl":"10.4103/jispcd.jispcd_28_25","url":null,"abstract":"<p><p>Oral health is closely linked to overall wellbeing among the elderly as poor oral hygiene can result in conditions like tooth loss, periodontal diseases, and xerostomia. The purpose of the current article is to justify the need for maintaining oral health among the elderly, identify the barriers that can prevent maintenance of oral health, and propose potential interventions to overcome these identified barriers. To ensure that elderly people have an adequate intake of essential nutrients, they must have healthy teeth and gums, which enable them to chew foods efficiently. Elderly people with good oral health tend to have clear speech and effective communication, which improves their self-confidence and eliminates the possibility of being socially isolated. Despite the presence of multiple benefits of good oral health, there are multiple constraints that can limit the maintenance of optimal oral health among the elderly. Acknowledging the significance of maintaining oral health and the presence of different barriers that can interfere with the maintenance of optimal oral health among the elderly, there is an indispensable need to implement specific interventions to improve the existing scenario. In conclusion, oral health is an integral component of the overall health and wellbeing of elderly people. The need of the hour is to implement a comprehensive package of interventions to ensure easy access to quality-assured oral healthcare services for the benefit of the elderly people.</p>","PeriodicalId":47247,"journal":{"name":"Journal of International Society of Preventive and Community Dentistry","volume":"15 3","pages":"296-299"},"PeriodicalIF":2.1,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12364397/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144974043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Oral Health and Climate Change: Working Toward Adaptive Strategies to the Changing Environment.","authors":"Saurabh RamBihariLal Shrivastava, Prateek Sudhakar Bobhate, Monal Kukde","doi":"10.4103/jispcd.jispcd_228_24","DOIUrl":"10.4103/jispcd.jispcd_228_24","url":null,"abstract":"<p><p>Climate change has been acknowledged as one of the current's century most significant global public health challenges. Climate change has resulted in a multifaceted impact on oral health, including the exacerbation of periodontal diseases, enamel erosion, and the increased risk of oral cancers. At the policy level, oral healthcare initiatives should be incorporated into climate adaptation strategies. Key recommendations include promoting climate-resilient dental practices (like mobile clinics and tele-dentistry), integrating sustainable oral healthcare practices, and advocating for water conservation. To summarize, these findings offer a blueprint to mitigate oral health disparities and augment the resilience of dental care systems, emphasizing the linkages between environmental policies and oral health outcomes.</p>","PeriodicalId":47247,"journal":{"name":"Journal of International Society of Preventive and Community Dentistry","volume":"15 2","pages":"192-195"},"PeriodicalIF":1.4,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12105816/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144161847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Raghad A Al-Askary, Wiaam M O Al-Ashou, Sawsan H Al-Jubori
{"title":"<i>In Vitro</i> Apatite-Forming Ability of Different Root Canal Sealers (A Comparative Study).","authors":"Raghad A Al-Askary, Wiaam M O Al-Ashou, Sawsan H Al-Jubori","doi":"10.4103/jispcd.jispcd_12_25","DOIUrl":"10.4103/jispcd.jispcd_12_25","url":null,"abstract":"<p><strong>Aim: </strong>Hydroxyapatite (HA) formation ability of endodontic sealers is considered an index of their bioactivity and plays a significant role in hard-tissue inductivity and elevating the sealing ability of the root canal system. This study evaluated and compared <i>in vitro</i> the apatite-forming ability of endodontic sealers after immersion in phosphate buffer saline (PBS).</p><p><strong>Methods: </strong>Eighty sealer specimens, 20 samples for each sealer (GuttaFlow2, GuttaFlow Bioseal, ProRoot mineral trioxide aggregate [MTA], and MTA Fillapex), measuring 1.0 ± 0.1 mm in thickness and 20 ± 0.1 mm in diameter, were prepared, then incubated at 37°C and 95% relative humidity for three times their setting time to ensure complete setting. The disc samples were de-molded, and 10 sealer discs of each sealer were immersed for 28 days in PBS, while the other discs were not immersed. Morphological and elemental analyses for the surface precipitate of each sealer's disc were analyzed with a field emission scanning electron microscope with energy-dispersive X-ray spectroscopy (FESEM). In addition, X-ray diffraction (XRD) and Raman spectroscopy analyses were used to assess the HA precipitate.</p><p><strong>Results: </strong>The FESEM revealed a superficial layer of apatite spherulites coated on (GuttaFlow Bioseal, ProRoot MTA, and MTA Fillapex) sealers after 28 days of immersion in PBS. The calcium to phosphorus (Ca/P) ratio of the coating indicated the formation of HA deposits which is higher for ProRoot MTA followed by MTA Fillapex and then by GuttaFlow Bioseal. Apatite deposits were confirmed by XRD through their characteristic peaks and Raman spectra through their band at 960 cm<sup>-1</sup>.</p><p><strong>Conclusions: </strong>This <i>in vitro</i> research approves the excellent bioactivity of ProRoot MTA. In addition, both MTA Fillapex and GuttaFlow Bioseal sealer have bioactive ability.</p>","PeriodicalId":47247,"journal":{"name":"Journal of International Society of Preventive and Community Dentistry","volume":"15 2","pages":"173-183"},"PeriodicalIF":1.4,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12105809/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144162937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nurfarhana Ilyas, Saraswathy Devi Sinniah, Norashikin Abu Bakar
{"title":"Assessment Factors for Managing First Permanent Molars in Children with Poor Prognosis: A Systematic Mapping of Clinical Evidence.","authors":"Nurfarhana Ilyas, Saraswathy Devi Sinniah, Norashikin Abu Bakar","doi":"10.4103/jispcd.jispcd_234_24","DOIUrl":"10.4103/jispcd.jispcd_234_24","url":null,"abstract":"<p><strong>Background: </strong>Managing the first permanent molar (FPM) with a poor prognosis can be challenging as it depends on several modifying factors that must be considered, and each approach has potential implications and clinical outcomes.</p><p><strong>Aim: </strong>This review aimed to systematically review the assessment factors that should be considered prior to managing FPM with poor prognosis in children.</p><p><strong>Methods: </strong>A computerized database search was conducted using Cochrane, PubMed, and Scopus with predefined search terms related to \"management, treatment, extraction, restoration, endodontic, and orthodontic\" involving the \"FPM.\" The search included studies published in English between 1990 and 2024. Two reviewers independently extracted data and assessed whether the studies met the inclusion criteria. The inclusion criteria specified management approaches for FPM with poor prognosis in children aged 6-16. Any disagreement between reviewers was resolved through discussion.</p><p><strong>Results: </strong>A total of 1815 studies were screened, and 37 full-text articles were retrieved. Seven retrospective observational studies met the inclusion criteria. All the included studies focused on orthodontic assessment factors, such as the presence of a third molar and angulation of the second permanent molar, aimed at achieving spontaneous space closure following FPM extraction. However, no studies have addressed restorative perspectives on managing this problem, particularly in pediatric patients.</p><p><strong>Conclusion: </strong>This review highlights a lack of well-established and robust studies on managing poor prognosis in FPM. The absence of research on long-term functional outcomes, patient-reported experiences, and the role of restorative alternatives, especially in children, reveals significant gaps in the current literature. Incorporating these findings into clinical practice could lead to more personalized and effective treatment strategies that focus on both immediate and long-term oral health outcomes for children. Given the complexity of FPM management, a multidisciplinary approach combining restorative, orthodontic, and preventive strategies is crucial. Therefore, further studies with stronger evidence are needed to explore a comprehensive clinical approach that could enhance treatment outcomes.</p>","PeriodicalId":47247,"journal":{"name":"Journal of International Society of Preventive and Community Dentistry","volume":"15 2","pages":"101-113"},"PeriodicalIF":1.4,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12105808/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144162939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}