{"title":"饮食和唾液氧化状态与牙根龋严重程度相关：一项病例对照研究。","authors":"Baydaa Ahmed Yas","doi":"10.4103/jispcd.jispcd_116_24","DOIUrl":null,"url":null,"abstract":"<p><strong>Aim: </strong>Root caries (RC) is a significant concern in older adults. Oxidative stress and dietary factors may play a role in its development and progression. However, the interactive effects of dietary total antioxidant capacity (dTAC) and RC severity (RCS) on salivary oxidative status in this population are not fully understood. This study aimed to assess dietary and salivary oxidative status and to investigate the interactive effect of RCS and dTAC on salivary total antioxidant capacity (TAC) and total oxidative status (TOS) in older adults.</p><p><strong>Materials and methods: </strong>A case-control study was conducted with 90 participants aged 50-60 years recruited from a university dental hospital. Participants were allocated into six groups (<i>n</i> = 15/group) based on dTAC (high/low) and RCS (none, incipient, and shallow). dTAC was measured using the ferric reducing-antioxidant power assay. Salivary TAC and TOS levels were measured using colorimetric kits. RCS was clinically diagnosed. Data were analyzed using two-way analysis of variance (ANOVA), two-way multivariate ANOVA, and Pearson's correlation coefficient.</p><p><strong>Results: </strong>Salivary TAC was significantly higher in participants with high dTAC (<i>P</i> < 0.05) and increased with increasing RCS (<i>P</i> < 0.01). Salivary TOS was lower in those with high dTAC (<i>P</i> < 0.01) and increased with increasing RCS (<i>P</i> < 0.01). A significant interactive effect of RCS and dTAC on both TAC and TOS was observed (<i>P</i> < 0.01).</p><p><strong>Conclusion: </strong>Both dietary TAC and RC S have significant, independent, and interactive effects on salivary oxidative status among older adults. A diet high in antioxidants may improve salivary oxidative status and potentially mitigate the severity of RC. Dietary interventions aimed at increasing antioxidant intake may be a valuable adjunct to conventional RC prevention strategies in older adults. Further research should explore the long-term impact of dietary antioxidants on RC incidence and progression, and investigate specific antioxidant compounds and their mechanisms of action in larger, more diverse populations.</p>","PeriodicalId":47247,"journal":{"name":"Journal of International Society of Preventive and Community Dentistry","volume":"15 4","pages":"364-373"},"PeriodicalIF":2.1000,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12425397/pdf/","citationCount":"0","resultStr":"{\"title\":\"Dietary and Salivary Oxidative Status Related to Root Caries Severity: A Case-Control Study.\",\"authors\":\"Baydaa Ahmed Yas\",\"doi\":\"10.4103/jispcd.jispcd_116_24\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Aim: </strong>Root caries (RC) is a significant concern in older adults. Oxidative stress and dietary factors may play a role in its development and progression. However, the interactive effects of dietary total antioxidant capacity (dTAC) and RC severity (RCS) on salivary oxidative status in this population are not fully understood. This study aimed to assess dietary and salivary oxidative status and to investigate the interactive effect of RCS and dTAC on salivary total antioxidant capacity (TAC) and total oxidative status (TOS) in older adults.</p><p><strong>Materials and methods: </strong>A case-control study was conducted with 90 participants aged 50-60 years recruited from a university dental hospital. Participants were allocated into six groups (<i>n</i> = 15/group) based on dTAC (high/low) and RCS (none, incipient, and shallow). dTAC was measured using the ferric reducing-antioxidant power assay. Salivary TAC and TOS levels were measured using colorimetric kits. RCS was clinically diagnosed. Data were analyzed using two-way analysis of variance (ANOVA), two-way multivariate ANOVA, and Pearson's correlation coefficient.</p><p><strong>Results: </strong>Salivary TAC was significantly higher in participants with high dTAC (<i>P</i> < 0.05) and increased with increasing RCS (<i>P</i> < 0.01). Salivary TOS was lower in those with high dTAC (<i>P</i> < 0.01) and increased with increasing RCS (<i>P</i> < 0.01). A significant interactive effect of RCS and dTAC on both TAC and TOS was observed (<i>P</i> < 0.01).</p><p><strong>Conclusion: </strong>Both dietary TAC and RC S have significant, independent, and interactive effects on salivary oxidative status among older adults. A diet high in antioxidants may improve salivary oxidative status and potentially mitigate the severity of RC. Dietary interventions aimed at increasing antioxidant intake may be a valuable adjunct to conventional RC prevention strategies in older adults. Further research should explore the long-term impact of dietary antioxidants on RC incidence and progression, and investigate specific antioxidant compounds and their mechanisms of action in larger, more diverse populations.</p>\",\"PeriodicalId\":47247,\"journal\":{\"name\":\"Journal of International Society of Preventive and Community Dentistry\",\"volume\":\"15 4\",\"pages\":\"364-373\"},\"PeriodicalIF\":2.1000,\"publicationDate\":\"2025-08-14\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12425397/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of International Society of Preventive and Community Dentistry\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4103/jispcd.jispcd_116_24\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/7/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q3\",\"JCRName\":\"DENTISTRY, ORAL SURGERY & MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of International Society of Preventive and Community Dentistry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/jispcd.jispcd_116_24","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/7/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}
Dietary and Salivary Oxidative Status Related to Root Caries Severity: A Case-Control Study.
Aim: Root caries (RC) is a significant concern in older adults. Oxidative stress and dietary factors may play a role in its development and progression. However, the interactive effects of dietary total antioxidant capacity (dTAC) and RC severity (RCS) on salivary oxidative status in this population are not fully understood. This study aimed to assess dietary and salivary oxidative status and to investigate the interactive effect of RCS and dTAC on salivary total antioxidant capacity (TAC) and total oxidative status (TOS) in older adults.
Materials and methods: A case-control study was conducted with 90 participants aged 50-60 years recruited from a university dental hospital. Participants were allocated into six groups (n = 15/group) based on dTAC (high/low) and RCS (none, incipient, and shallow). dTAC was measured using the ferric reducing-antioxidant power assay. Salivary TAC and TOS levels were measured using colorimetric kits. RCS was clinically diagnosed. Data were analyzed using two-way analysis of variance (ANOVA), two-way multivariate ANOVA, and Pearson's correlation coefficient.
Results: Salivary TAC was significantly higher in participants with high dTAC (P < 0.05) and increased with increasing RCS (P < 0.01). Salivary TOS was lower in those with high dTAC (P < 0.01) and increased with increasing RCS (P < 0.01). A significant interactive effect of RCS and dTAC on both TAC and TOS was observed (P < 0.01).
Conclusion: Both dietary TAC and RC S have significant, independent, and interactive effects on salivary oxidative status among older adults. A diet high in antioxidants may improve salivary oxidative status and potentially mitigate the severity of RC. Dietary interventions aimed at increasing antioxidant intake may be a valuable adjunct to conventional RC prevention strategies in older adults. Further research should explore the long-term impact of dietary antioxidants on RC incidence and progression, and investigate specific antioxidant compounds and their mechanisms of action in larger, more diverse populations.
期刊介绍：
It is a journal aimed for research, scientific facts and details covering all specialties of dentistry with a good determination for exploring and sharing the knowledge in the medical and dental fraternity. The scope is therefore huge covering almost all streams of dentistry - starting from original studies, systematic reviews, narrative reviews, very unique case reports. Journal scope is not limited to these subjects and is more wider covering all specialities of dentistry follows: -Preventive and Community dentistry (Dental public health)- Endodontics- Oral and maxillofacial pathology- Oral and maxillofacial radiology- Oral and maxillofacial surgery (also called oral surgery)- Orthodontics and dentofacial orthopedics- Periodontology (also called periodontics)- Pediatric dentistry (also called pedodontics)- Prosthodontics (also called prosthetic dentistry)- Oral medicine- Special needs dentistry (also called special care dentistry)- Oral Biology- Forensic odontology- Geriatric dentistry or Geriodontics- Preventive and Social Medicine (Public health)- Our journal appreciates research articles pertaining with advancement of dentistry, preventive and community dentistry including oral epidemiology, oral health services research, oral health education and promotion, behavioral sciences related to dentistry, dental jurisprudence, ethics and oral health, economics, and quality assessment, recent advances in preventive dentistry and community dentistry.
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