Abdel-Naser M Emam, Esmail Ahmed Abdel-Gawwad, Abdel Aziz Abdullah Baiomy, Mostafa Yassin Farhat, Ehap Atito, Mohamed Ahmed Helal
{"title":"Efficacy of Occlusal Splints and Low-Level Laser Therapy on the Mandibular Range of Motion in Subjects with Temporomandibular Joint Disc Displacement with Reduction.","authors":"Abdel-Naser M Emam, Esmail Ahmed Abdel-Gawwad, Abdel Aziz Abdullah Baiomy, Mostafa Yassin Farhat, Ehap Atito, Mohamed Ahmed Helal","doi":"10.4103/jispcd.JISPCD_159_22","DOIUrl":"https://doi.org/10.4103/jispcd.JISPCD_159_22","url":null,"abstract":"<p><strong>Aims and objectives: </strong>The study was carried out to evaluate the efficacy of four conservative therapeutic modalities on the mandibular range of motion (MRM) in subjects with anterior disc displacement with reduction (ADDwR) of the temporomandibular joint (TMJ).</p><p><strong>Materials and methods: </strong>One hundred patients (64 women and 36 men) were selected, and randomly distributed into four groups. Group I: Subjects receiving behavioral therapy (BT). Group II: Subjects receiving low-level laser therapy (LLLT). Group III: Subjects receiving maxillary anterior repositioning splint (MARS). Group IV: Subjects receiving stabilization splint (SS). The MRM was evaluated for each patient before treatment and after 6 months. Paired <i>t</i> test and one-way analysis of variance (ANOVA) tests were used for statistical analysis followed by a <i>post hoc</i> Tukey test (<i>P</i> ≤ 0.05).</p><p><strong>Results: </strong>All groups showed significant improvement in MRM after 6 months of treatment (<i>P</i> ≤ 0.05) except for BT. There was a significant improvement for SS and MARS on the different movements of MRM, more than for LLLT and BT (<i>P</i> ≤ 0.05).</p><p><strong>Conclusion: </strong>The MARS and the SS are effective in increasing the MRM for patients with ADDwR.</p>","PeriodicalId":47247,"journal":{"name":"Journal of International Society of Preventive and Community Dentistry","volume":"13 3","pages":"229-236"},"PeriodicalIF":1.1,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/19/bc/JISPCD-13-229.PMC10411297.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10032563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Edith Perez, Liliana Salinas, Roman Mendoza, Maria Eugenia Guerrero, Jose Oliva, Frank Mayta-Tovalino
{"title":"Osseointegration of Dental Implants in Patients with Congenital and Degenerative Bone Disorders: A Literature Review.","authors":"Edith Perez, Liliana Salinas, Roman Mendoza, Maria Eugenia Guerrero, Jose Oliva, Frank Mayta-Tovalino","doi":"10.4103/jispcd.JISPCD_51_22","DOIUrl":"https://doi.org/10.4103/jispcd.JISPCD_51_22","url":null,"abstract":"<p><strong>Aims and objectives: </strong>The aim of this study was to describe the mechanism of dental implants osseointegration in patients with congenital and degenerative genetic bone disorders.</p><p><strong>Materials and methods: </strong>A PubMed and Scopus documents search was carried out between November 2021 in the, using words such as \"osseointegration,\" \"degenerative disease,\" \"congenital disease,\" and \"dental implants.\"</p><p><strong>Results: </strong>The thirteen articles selected dealt with dental implants osseointegration in patients with congenital and degenerative bone disorders. The influence and repercussion of these diseases on the bone system, as well as the osseointegration process were described from healing to bone remodeling. In addition, certain articles described some considerations to improve the osseointegration process in patients suffering from these types of conditions.</p><p><strong>Conclusions: </strong>Within the limitations of this literature review we can conclude that osseointegration in patients with ectodermal dysplasia and osteoporosis could be achieved. However, the planning process for dental implant placement in these patients should be more meticulous and individualized considering the degree of tissue involvement as well as the patient's age and skeletal development compared to systemically healthy patients.</p>","PeriodicalId":47247,"journal":{"name":"Journal of International Society of Preventive and Community Dentistry","volume":"13 3","pages":"167-172"},"PeriodicalIF":1.1,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d2/98/JISPCD-13-167.PMC10411298.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9978938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Neil Vincent Lewis, Shalini Aggarwal, Nikhil N Borse, Shailendra Sonawane, Prasanna Dhatavkar, Rhea Digholkar, Divyanshi Agarwal
{"title":"The Effect of Matrix Metalloproteinase Inhibitors on the Microtensile Bond Strength of Dentin Bonding Agents in Caries Affected Dentin: A Systematic Review.","authors":"Neil Vincent Lewis, Shalini Aggarwal, Nikhil N Borse, Shailendra Sonawane, Prasanna Dhatavkar, Rhea Digholkar, Divyanshi Agarwal","doi":"10.4103/jispcd.JISPCD_5_23","DOIUrl":"https://doi.org/10.4103/jispcd.JISPCD_5_23","url":null,"abstract":"<p><strong>Aims and objectives: </strong>Matrix metalloproteinases (MMPs) cause degradation of the dentinal matrix, as they act actively on collagen fibrils, leading to their deterioration and collapse. MMP inhibitors are known to be used for the pre-treatment of human dentin before bonding. Most studies on the MMP inhibitors examined the effect of MMP inhibitors on bonding to sound dentin (SD), but few examine their effect on bonding to caries affected dentin (CAD). This systematic review aims to identify and summarize studies that have applied MMP inhibitors for pre-treatment of CAD, and examine the microtensile bond strength (µTBS), bond durability, and the mode of failure.</p><p><strong>Materials and methods: </strong>A systematic review was performed using the PubMed database according to the PRISMA guidelines. A total of 785 original articles published between 2010 and 2022 were initially retrieved. Six studies were selected based on predefined inclusion-exclusion criteria, and their outcomes were extracted and analyzed. The methodological quality assessment was performed using a combined checklist that utilizes the reporting criteria mentioned in the checklist for reporting in-vitro studies guidelines and guidelines for reporting pre-clinical <i>in vitro</i> studies on dental materials.</p><p><strong>Results: </strong>All six studies included here showed a definitive increase of the µTBS when MMP inhibitors were applied to the CAD. The mode of failure was found to be predominantly adhesive in nature. The deviation in the values of µTBS was approximately 2-5 MPa on immediate and delayed testing.</p><p><strong>Conclusion: </strong>MMP-inhibiting agents could be considered for the pretreatment of teeth with CAD as a part of their tooth preparation area, thereby allowing the clinician to retain CAD and bond to the CAD without endangering the vital pulp.</p>","PeriodicalId":47247,"journal":{"name":"Journal of International Society of Preventive and Community Dentistry","volume":"13 3","pages":"173-184"},"PeriodicalIF":1.1,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/77/90/JISPCD-13-173.PMC10411291.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9978939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Identification of Potential Molecular Mechanisms and Prognostic Markers for Oral Squamous Cell Carcinoma: A Bioinformatics Analysis.","authors":"Suthipong Chujan, Nakarin Kitkumthorn, Jutamaad Satayavivad","doi":"10.4103/jispcd.JISPCD_15_23","DOIUrl":"https://doi.org/10.4103/jispcd.JISPCD_15_23","url":null,"abstract":"<p><strong>Aims and objectives: </strong>The goal of this study was to uncover crucial biochemical pathways, prognostic indicators, and therapeutic targets in patients with oral cancer in order to enhance therapy strategies.</p><p><strong>Materials and methods: </strong>Five gene expression omnibus datasets were analyzed by using bioinformatics approaches to identify differentially expressed genes (DEGs). To determine biological alterations, gene ontology (GO) and KEGG pathway analyses were implied using the identified DEGs. Hub genes were determined using protein-protein interaction (PPI) network analysis and an interactome was constructed using NetworkAnalyst. Furthermore, five hub genes were evaluated for use as prognostic markers by using the human protein atlas (HPA) and the GEPIA2.0 database. In addition, the correlations between hub-gene expression and immune cell infiltration of oral squamous cell carcinoma (OSCC) tumors were analyzed using the tWumor immune estimation resource (TIMER) database.</p><p><strong>Results: </strong>A total of 2071 upregulated genes and 1893 downregulated genes were identified. GO and pathway analysis showed DEGs were enriched in multiple immune response terms and interaction of inflammatory cytokines. From the PPI network, five hub genes were identified that have a crucial role in OSCC. These included interferon regulatory factor 4 (IRF4), chemokine receptor 7 (CCR7), TNF receptor superfamily member 17 (TNFRSF17), CD27, and sphingosine-1-phosphate receptor 4 (S1PR4), which were predicted to be favorable prognostic markers for OSCC using HPA. Overall survival analysis revealed that low expression of the five hub genes was significantly associated with worse overall survival. Our analysis of tumor-associated immune infiltration revealed that increased IRF4 expression was positively correlated with the gene expression profiles suggestive of infiltration of all immune cell types, whereas increased CCR7 expression was negatively correlated with neutrophil infiltration. Increased expression of CD27, S1PR4, and TNFRSF17 was found to be negatively correlated with dendritic cell, M0 macrophage, and neutrophil infiltration.</p><p><strong>Conclusion: </strong>In summary, inflammation, and the immune response play an important role in OSCC. All five hub genes were good predictors of OSCC prognosis, suggesting that they could be used as potential therapeutic targets and tumor markers.</p>","PeriodicalId":47247,"journal":{"name":"Journal of International Society of Preventive and Community Dentistry","volume":"13 3","pages":"237-246"},"PeriodicalIF":1.1,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c8/ee/JISPCD-13-237.PMC10411293.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9978940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Analysis of Epstein-Barr Virus Infection in Oral Potentially Malignant Disorders and Oral Cancer: A Cross-Sectional Study.","authors":"Jintana Pankam, Puangwan Lapthanasupkul, Nakarin Kitkumthorn, Dulyapong Rungraungrayabkul, Boworn Klongnoi, Siribang-On Piboonniyom Khovidhunkit","doi":"10.4103/jispcd.JISPCD_235_22","DOIUrl":"https://doi.org/10.4103/jispcd.JISPCD_235_22","url":null,"abstract":"<p><strong>Aims and objectives: </strong>The primary objective of this study is to determine the prevalence of Epstein-Barr virus (EBV) in oral potentially malignant disorders (OPMDs) and oral cancer (OC) in a group of Thais using polymerase chain reaction (PCR) and Epstein-Barr encoding regions (<i>EBERs</i>) <i>in situ</i> hybridization (ISH). The secondary objective is to investigate the risk factors of OC and the association between the presence of EBV and risk factors of OC/site of oral lesions.</p><p><strong>Materials and methods: </strong>Sixty-one participants attending the screening project for OC and OPMDs at the Northeastern district hospitals of Thailand were recruited. Information related to risk factors and biopsy tissues for histopathological diagnosis was collected. Sixty-seven paraffin tissue blocks, including 52 OPMDs and 15 OC specimens, were investigated for EBV infection, using PCR analysis with latent membrane protein-1 (<i>LMP-1</i>) primer and <i>EBERs</i> ISH. Pearson's Chi-square or Fisher's exact test was used to analyze the differences in variables between participants with OPMDs and OC, as appropriate. The association between EBV infection and related risk factors was analyzed using logistic regression with a significant level at 0.05.</p><p><strong>Results: </strong>Using PCR analysis, 8 of 67 specimens (11.94%) were positive for <i>LMP-1.</i> Three cases of OPMDs were positive for both <i>LMP-1</i> PCR and <i>EBERs</i> ISH. Regarding risk factors of OC, the two most common risk factors were betel nut chewing (52.46%) and working in sunlight (42.62%). The habit of taking alcohol was significantly different between the OC and the OPMDs groups (<i>p</i> = 0.009). The association between <i>LMP-1</i> and the lesion at the tongue was statistically significant, with odds ratio = 4.900 (95% confidence interval = 1.046-22.943; <i>p</i> = 0.044).</p><p><strong>Conclusions: </strong>The prevalence of EBV infection in this group of participants was low. However, OPMDs at the tongue exhibited a significant association with EBV infection.</p>","PeriodicalId":47247,"journal":{"name":"Journal of International Society of Preventive and Community Dentistry","volume":"13 3","pages":"221-228"},"PeriodicalIF":1.1,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/87/1a/JISPCD-13-221.PMC10411295.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9978935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prevalence of Dental trauma in Permanent anterior teeth among school children in Villupuram District","authors":"Vansy Merlin Yesupatham, Arungani NS, Kalaivani V","doi":"10.56501/intjcommunitydent.v11i1.753","DOIUrl":"https://doi.org/10.56501/intjcommunitydent.v11i1.753","url":null,"abstract":"Introduction: Traumatic tooth injuries range in severity from minor fractures of the enamel to whole tooth displacement (avulsion) brought on by a forceful blow to the tooth's supporting components. The aim of this study is to determine the prevalence of fracture in anterior teeth of children aged between 8 - 15 years, in different villages of Villupuram district.\u0000Materials and Methods: This cross-sectional epidemiological study has adopted multi stage sampling design. Study was conducted in various schools in Villupuram district. A Type III clinical examination was carried out in just the correct quantity of natural light. Every participant who showed up on the exam day was included in the study. Patient’s Demographic details were collected followed by screening fractured teeth using Ellis Fracture classification and reason for fracture.\u0000Result: Nearly 15% of the population had fractures in anterior teeth. Boy children had more fractures in anterior teeth compared to girl children. Most of the children had Ellis Class II Fracture followed by Ellis Class I fracture\u0000Conclusion: Increased prevalence indicates the importance to formulate treatment plan and facilities in primary health centres to treat the injuries.","PeriodicalId":47247,"journal":{"name":"Journal of International Society of Preventive and Community Dentistry","volume":"19 1","pages":""},"PeriodicalIF":1.1,"publicationDate":"2023-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81711401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dental Fluorosis – A Review","authors":"Sivashankari Boobalan, Logesh Sidhu","doi":"10.56501/intjcommunitydent.v11i1.695","DOIUrl":"https://doi.org/10.56501/intjcommunitydent.v11i1.695","url":null,"abstract":"Dental fluorosis is a dental enamel development disturbance caused by repeated exposure to high fluoride concentrations during tooth development, resulting in enamel with a lower mineral content and more porosity. Dental fluorosis shows white opaque appearance of hypomineralized enamel subsurface, with pitting and subsequent loss of enamel surface leads to brown color. The lesions take place in these forms : hypoplasia of dental enamel, pitting, decalcified areas, mottling, brownin. Fluorides are always considered as double-edged sword. Fluorides are necessary for the healthy growth and development of the body, however excessive fluoride intake can be harmful and causes severe deformities by understanding the sources of fluoride, knowing to avoid over exposure, fluorosis can be prevented. They are also treated with bleaching, micro abrasion, resin infiltration, resin infiltration with bleaching, and microabrasion with bleaching.","PeriodicalId":47247,"journal":{"name":"Journal of International Society of Preventive and Community Dentistry","volume":"6 1","pages":""},"PeriodicalIF":1.1,"publicationDate":"2023-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82223662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohammed Abidullah, Prashanth Nahar, Syed Afroze Ahmed, Hemant Kothari, Sana Vakeel
{"title":"MUC4 Expression in Oral Dysplastic Epithelium and Oral Squamous Cell Carcinoma: An Immunohistochemical Study.","authors":"Mohammed Abidullah, Prashanth Nahar, Syed Afroze Ahmed, Hemant Kothari, Sana Vakeel","doi":"10.4103/jispcd.JISPCD_241_22","DOIUrl":"https://doi.org/10.4103/jispcd.JISPCD_241_22","url":null,"abstract":"<p><strong>Objective: </strong>MUCIN4 (MUC4) glycosylation is linked to the oncogenesis and progression of a neoplastic process. It can suggest information pertaining to tumor progression, management and its natural properties. Thus, MUC4 can play a pivotal role in prognostic diagnosis. This study aimed to analyze the MUC4 expression in oral cell squamous carcinoma and oral dysplastic epithelium.</p><p><strong>Materials and methods: </strong>The research included 45 samples of oral epithelial dysplasia (OED) and 45 cases of oral squamous cell carcinoma (OSCC). In order to carry out the investigation, tissue blocks of previously diagnosed cases of OED and OSCC were retrieved from the relevant archives. Forty-five OED cases were categorized into three group's mild, moderate and severe dysplasia, with 15 cases in each respective category. Forty-five OSCC cases were categorized into three groups: well differentiated, moderately differentiated, and poorly differentiated OSCC with 15 cases in each respective category. Ten tissue biopsies of normal oral mucosa were obtained from subjects in the control group. The chi-square test and one-way ANOVA were used for statistical analysis.</p><p><strong>Result: </strong>There was an absence of MUC4 expression in normal mucosa, whereas the OED and OSCC groups had a significant amount of observable variance. Within the OED category of cases, a consistent progression from mild to severe dysplasia was seen in terms of the staining pattern. Cases with severe dysplasia displayed a staining pattern that covered the complete thickness of the tissue in the epithelium. Expression of MUC4 was shown to be lower in moderate differentiated squamous cell carcinoma (MDSCC), and poorly differentiated squamous cell carcinoma (PDSCC) as compared to well differentiated squamous cell carcinoma (WDSCC). It showed decreasing pattern across all grades of OSCC. In WDSCC, an intense highest staining response was noticed, particularly among the cells that are highly differentiated and take the form of a honeycomb pattern.</p><p><strong>Conclusion: </strong>Analysis of the expression profile of MUC4 and the aberrant expression of this gene in OSCC suggests that it may serve as a useful diagnostic marker. Therefore, it is possible to draw the conclusion that MUC4 plays a very significant part in the pathogenesis of OSCC and also acts as a marker that may be taken into consideration for the accurate diagnosis of OED and OSCC.</p>","PeriodicalId":47247,"journal":{"name":"Journal of International Society of Preventive and Community Dentistry","volume":"13 2","pages":"124-132"},"PeriodicalIF":1.1,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d5/19/JISPCD-13-124.PMC10202254.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9569986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sonia Gupta, Harman Sandhu, Karthick T Nadar, Rosa L Ocampo Escobedo, Radhika Gupta, Anitha Subbappa, Harkaran S Bhullar, Manjinder Kaur
{"title":"Plasma Fibrinogen Degradation Products as the Nonsurgical Diagnostic Tool for Oral Submucous Fibrosis: A Systematic Review.","authors":"Sonia Gupta, Harman Sandhu, Karthick T Nadar, Rosa L Ocampo Escobedo, Radhika Gupta, Anitha Subbappa, Harkaran S Bhullar, Manjinder Kaur","doi":"10.4103/jispcd.JISPCD_229_22","DOIUrl":"https://doi.org/10.4103/jispcd.JISPCD_229_22","url":null,"abstract":"<p><strong>Aims and objectives: </strong>Oral submucous fibrosis (OSMF) is known to be one of the most common premalignant conditions of the oral cavity. Areca nut (AN) is considered to be the disease's primary cause, while there are other potential causes as well. However, routine clinical practice has revealed that not all people who chew AN exhibit clinical signs of OSMF, and few people are reported to have it even without chewing AN. So, there must be other factors contributing to OSMF. Plasma fibrinogen degradation products (FDPs) have recently been discovered to be an early sign of this disease, indicating a potential link between the two. This review aims to examine the studies which have been published in the literature that explain the role of plasma FDPs in contributing to OSMF.</p><p><strong>Materials and methods: </strong>An electronic search of the published literature was performed without publication year limitation in PubMed/ Medline, Scopus, Google Scholar, Web of Science, Science Direct, Embase, and Research gate databases, using mesh keywords like ('Oral submucous fibrosis' OR 'Oral submucous fibrosis') AND ('Fibrinogen degradation products' OR 'Plasma fibrinogen degradation products') AND ('Clinical grades' OR 'Histological grades') AND ('Diagnosis'). A manual search of all related journals was also done. We also referred to the reference lists of papers. The risk of bias was evaluated with the GRADE criteria (from the Grading of Recommendations Assessment, Development, and Evaluation Working Group).</p><p><strong>Results: </strong>The search revealed a total of 12 relevant studies from 1979 to 2022. Nine out of 12 studies demonstrated the definite presence of plasma FDPs in such cases.</p><p><strong>Conclusions: </strong>Although the studies documented in the literature showing evidence of plasma FDPs in patients with OSMF are very few in number, their detection signifies an important clinical finding. More research is still required in this aspect to establish stronger evidence.</p>","PeriodicalId":47247,"journal":{"name":"Journal of International Society of Preventive and Community Dentistry","volume":"13 2","pages":"89-95"},"PeriodicalIF":1.1,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d1/c2/JISPCD-13-89.PMC10202252.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9871512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cristhel Juarez, Luis Langa, Roman Mendoza, Maria E Guerrero, Jose Oliva, Frank Mayta-Tovalino
{"title":"Antimicrobial Photodynamic Therapy for the Treatment of Peri-implantitis: A Literature Review.","authors":"Cristhel Juarez, Luis Langa, Roman Mendoza, Maria E Guerrero, Jose Oliva, Frank Mayta-Tovalino","doi":"10.4103/jispcd.JISPCD_44_22","DOIUrl":"https://doi.org/10.4103/jispcd.JISPCD_44_22","url":null,"abstract":"<p><strong>Aim: </strong>The aim of this article is to describe the existing scientific literature on photodynamic therapy (PDT) effectiveness for peri-implantitis treatment.</p><p><strong>Materials and methods: </strong>A date-restricted electronic search strategy was performed in PubMed and Scopus databases. The following words were used: \"peri-implant photodynamic therapy,\" \"photodynamic therapy in implantology,\" \"effectives of photodynamic therapy in peri-implantitis,\" \"Antimicrobial Photodynamic Therapy,\" \"Photodynamic Therapy for the treatment of peri-implantitis,\" and \"Mechanical debridement and photodynamic therapy in implantology.\"</p><p><strong>Results: </strong>Of the 15 articles, 13 articles were selected, of which 11 were prospective and experimental studies and 2 were longitudinal. The PDT effectiveness of peri-implantitis inflammation treatment was the most reported and investigated.</p><p><strong>Conclusion: </strong>There is scientific evidence that may support the use of PDT for peri-implantitis treatments. However, even more studies would still be needed to have solid evidence.</p>","PeriodicalId":47247,"journal":{"name":"Journal of International Society of Preventive and Community Dentistry","volume":"13 2","pages":"83-88"},"PeriodicalIF":1.1,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/70/d9/JISPCD-13-83.PMC10202255.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9871515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}