Clinical and Radiographic Outcomes Following Pulpotomy Using Biodentine in Carious Exposed Mature Permanent Teeth: A Systematic Review and Meta-analysis.
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引用次数: 0
Abstract
Aim: Vital pulp therapy is increasingly used in managing mature permanent teeth exposed to caries. Biodentine, a tricalcium silicate-based material, has emerged as a potential alternative to mineral trioxide aggregate (MTA) in pulpotomy procedures due to its favorable properties of handling and biocompatibility. The aim was to systematically evaluate and compare the clinical and radiographic outcomes of biodentine and MTA as pulpotomy agents in mature permanent teeth exposed to caries.
Materials and methods: This systematic review and meta-analysis was registered with International Prospective Register of Systematic Reviews (CRD4202457708) and followed Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020 guidelines. A comprehensive search of MEDLINE, Scopus, EBSCOhost, OpenGrey, and relevant journals was conducted up to August 31, 2024, to identify randomized controlled trials (RCTs). Studies comparing biodentine and MTA in mature permanent teeth with carious pulp exposure were included. The risk of bias was assessed using the Joanna Briggs Institute checklist, and statistical analysis was conducted using RevMan 5.4. The certainty of evidence was graded using the Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) approach.
Results: Seven RCTs were included in the systematic review, of which three were eligible for meta-analysis. The pooled results showed no significant difference between biodentine and MTA regarding clinical and radiographic success (odds ratio = 0.77; 95% confidence interval: 0.24-2.49; P = 0.66). Heterogeneity was low (I2 = 0%), and no significant publication bias was detected. However, the GRADE assessment rated the certainty of evidence as low due to imprecision and potential risk of bias.
Conclusion: Both biodentine and MTA demonstrate comparable clinical and radiographic success as pulpotomy agents in mature permanent teeth exposed to caries pulp. Given its advantageous handling and lower discoloration potential, biodentine may serve as a suitable alternative to MTA. Further high-quality trials are warranted to strengthen the current evidence base.
期刊介绍：
It is a journal aimed for research, scientific facts and details covering all specialties of dentistry with a good determination for exploring and sharing the knowledge in the medical and dental fraternity. The scope is therefore huge covering almost all streams of dentistry - starting from original studies, systematic reviews, narrative reviews, very unique case reports. Journal scope is not limited to these subjects and is more wider covering all specialities of dentistry follows: -Preventive and Community dentistry (Dental public health)- Endodontics- Oral and maxillofacial pathology- Oral and maxillofacial radiology- Oral and maxillofacial surgery (also called oral surgery)- Orthodontics and dentofacial orthopedics- Periodontology (also called periodontics)- Pediatric dentistry (also called pedodontics)- Prosthodontics (also called prosthetic dentistry)- Oral medicine- Special needs dentistry (also called special care dentistry)- Oral Biology- Forensic odontology- Geriatric dentistry or Geriodontics- Preventive and Social Medicine (Public health)- Our journal appreciates research articles pertaining with advancement of dentistry, preventive and community dentistry including oral epidemiology, oral health services research, oral health education and promotion, behavioral sciences related to dentistry, dental jurisprudence, ethics and oral health, economics, and quality assessment, recent advances in preventive dentistry and community dentistry.
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