Dietary and Salivary Oxidative Status Related to Root Caries Severity: A Case-Control Study.

IF 2.1 Q3 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of International Society of Preventive and Community Dentistry Pub Date : 2025-08-14 eCollection Date: 2025-07-01 DOI:10.4103/jispcd.jispcd_116_24

Baydaa Ahmed Yas

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引用次数: 0

Abstract

Aim: Root caries (RC) is a significant concern in older adults. Oxidative stress and dietary factors may play a role in its development and progression. However, the interactive effects of dietary total antioxidant capacity (dTAC) and RC severity (RCS) on salivary oxidative status in this population are not fully understood. This study aimed to assess dietary and salivary oxidative status and to investigate the interactive effect of RCS and dTAC on salivary total antioxidant capacity (TAC) and total oxidative status (TOS) in older adults.

Materials and methods: A case-control study was conducted with 90 participants aged 50-60 years recruited from a university dental hospital. Participants were allocated into six groups (n = 15/group) based on dTAC (high/low) and RCS (none, incipient, and shallow). dTAC was measured using the ferric reducing-antioxidant power assay. Salivary TAC and TOS levels were measured using colorimetric kits. RCS was clinically diagnosed. Data were analyzed using two-way analysis of variance (ANOVA), two-way multivariate ANOVA, and Pearson's correlation coefficient.

Results: Salivary TAC was significantly higher in participants with high dTAC (P < 0.05) and increased with increasing RCS (P < 0.01). Salivary TOS was lower in those with high dTAC (P < 0.01) and increased with increasing RCS (P < 0.01). A significant interactive effect of RCS and dTAC on both TAC and TOS was observed (P < 0.01).

Conclusion: Both dietary TAC and RC S have significant, independent, and interactive effects on salivary oxidative status among older adults. A diet high in antioxidants may improve salivary oxidative status and potentially mitigate the severity of RC. Dietary interventions aimed at increasing antioxidant intake may be a valuable adjunct to conventional RC prevention strategies in older adults. Further research should explore the long-term impact of dietary antioxidants on RC incidence and progression, and investigate specific antioxidant compounds and their mechanisms of action in larger, more diverse populations.

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饮食和唾液氧化状态与牙根龋严重程度相关：一项病例对照研究。

目的：牙根龋（RC）是老年人的一个重要问题。氧化应激和饮食因素可能在其发生和发展中起作用。然而，膳食总抗氧化能力（dTAC）和RC严重程度（RCS）对该人群唾液氧化状态的相互作用尚不完全清楚。本研究旨在评估老年人饮食和唾液氧化状态，并探讨RCS和dTAC对老年人唾液总抗氧化能力（TAC）和总氧化状态（TOS）的相互作用。材料与方法：从某大学牙科医院招募年龄在50 ~ 60岁的90例患者进行病例对照研究。根据dTAC（高/低）和RCS（无、早期和浅）将参与者分为六组（n = 15/组）。dTAC采用铁还原-抗氧化能力法测定。用比色试剂盒测定唾液TAC和TOS水平。临床诊断为RCS。数据分析采用双向方差分析（ANOVA）、双向多元方差分析（ANOVA）和Pearson相关系数。结果：高dTAC组唾液TAC显著升高（P < 0.05），且随RCS的增加而升高（P < 0.01）。高dTAC组唾液TOS较低（P < 0.01），随RCS的升高而升高（P < 0.01）。RCS和dTAC对TAC和TOS均有显著交互作用（P < 0.01）。结论：饮食中TAC和RC S对老年人唾液氧化状态有显著的、独立的和相互作用的影响。高抗氧化剂的饮食可以改善唾液氧化状态，并可能减轻RC的严重程度。旨在增加抗氧化剂摄入量的饮食干预可能是老年人传统RC预防策略的有价值的辅助手段。进一步的研究应该探索膳食抗氧化剂对RC发病率和进展的长期影响，并在更大、更多样化的人群中研究特定的抗氧化剂化合物及其作用机制。

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来源期刊

Journal of International Society of Preventive and Community Dentistry DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

2.50

自引率

0.00%

发文量

123

期刊介绍： It is a journal aimed for research, scientific facts and details covering all specialties of dentistry with a good determination for exploring and sharing the knowledge in the medical and dental fraternity. The scope is therefore huge covering almost all streams of dentistry - starting from original studies, systematic reviews, narrative reviews, very unique case reports. Journal scope is not limited to these subjects and is more wider covering all specialities of dentistry follows: -Preventive and Community dentistry (Dental public health)- Endodontics- Oral and maxillofacial pathology- Oral and maxillofacial radiology- Oral and maxillofacial surgery (also called oral surgery)- Orthodontics and dentofacial orthopedics- Periodontology (also called periodontics)- Pediatric dentistry (also called pedodontics)- Prosthodontics (also called prosthetic dentistry)- Oral medicine- Special needs dentistry (also called special care dentistry)- Oral Biology- Forensic odontology- Geriatric dentistry or Geriodontics- Preventive and Social Medicine (Public health)- Our journal appreciates research articles pertaining with advancement of dentistry, preventive and community dentistry including oral epidemiology, oral health services research, oral health education and promotion, behavioral sciences related to dentistry, dental jurisprudence, ethics and oral health, economics, and quality assessment, recent advances in preventive dentistry and community dentistry.