{"title":"Ophthalmic manifestations and management of Traboulsi syndrome in three children of a Saudi family.","authors":"Amal Alhemidan, Omar Khan, Khaled Al Qahtani","doi":"10.4103/sjopt.sjopt_219_24","DOIUrl":"10.4103/sjopt.sjopt_219_24","url":null,"abstract":"<p><p>Traboulsi syndrome is a rare genetic disorder characterized by dysmorphic facial features and ectopia lentis with high myopia. This condition is often associated with anterior segment abnormalities and spontaneous filtering blebs. Here, we present three children (siblings and one cousin) of one Saudi family with clinical features and genetic profiles consistent with this syndrome. Homozygous variant c.2062C>T, p.(Arg688*) gene were identified. Features such as anterior segment abnormalities and spontaneous filtering blebs were not present. One child was operated on in both eyes for lens subluxation by lens aspiration, anterior vitrectomy, and scleral-fixated intraocular lens implantation. Four months after surgery, uncorrected visual acuity was 20/20 in the right eye and 20/22.5 in the left eye. There was no spontaneous filtration bleb before or following surgery.</p>","PeriodicalId":46810,"journal":{"name":"Saudi Journal of Ophthalmology","volume":"40 1","pages":"99-102"},"PeriodicalIF":1.1,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13082555/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147699452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Age-related changes in the reticulin fibers of the lacrimal sac.","authors":"Hirohiko Kakizaki, Mohammad J Ali","doi":"10.4103/sjopt.sjopt_65_25","DOIUrl":"10.4103/sjopt.sjopt_65_25","url":null,"abstract":"<p><strong>Purpose: </strong>To microscopically analyze the changes in the lacrimal sac reticulin fibers with aging.</p><p><strong>Methods: </strong>Histological evaluation of seven lacrimal sac mucosae from five Indian patients (age and sex: 43-year-old male, 55-year-old female, 58-year-old female, 65-year-old female, and 73-year-old female) was performed. All the patients were diagnosed with primary acquired nasolacrimal duct obstruction. The mucosal walls of the lacrimal sacs were harvested during dacryocystorhinostomy or dacryocystectomy surgery. The specimens were fixed in 10% formalin and special staining with reticulin. The specimens were dehydrated and embedded in paraffin and cut into 7-μm-thick sections. The ratio of flexible and fragmented/thickened fibers (ratio f/ft) was estimated subjectively with a total score of 4. The score 4 meant that all fibers are the flexible type only but that of the score 0 does no flexible fibers.</p><p><strong>Results: </strong>All the lacrimal sac mucosae demonstrated the subepithelial presence of reticulin fibers. As age advanced, the ratio f/ft tended to be lower, reflecting degenerative changes. The laterality difference was minimal in bilateral specimens.</p><p><strong>Conclusion: </strong>The reticulin fibers were illustrated in the lacrimal sacs and demonstrated degenerative changes with advancing age. These changes may potentially alter the tissue tonicity and contribute to the pathogenesis of lacrimal drainage disorders as the age increases.</p>","PeriodicalId":46810,"journal":{"name":"Saudi Journal of Ophthalmology","volume":"39 3","pages":"243-245"},"PeriodicalIF":1.2,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12578428/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145432643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Local anesthesia in upper eyelid surgery - Some considerations.","authors":"Samata Sharma, Jose M Ambat, Hirohiko Kakizaki","doi":"10.4103/sjopt.sjopt_59_25","DOIUrl":"10.4103/sjopt.sjopt_59_25","url":null,"abstract":"<p><p>Local anesthesia injection into the upper eyelid is usually performed with the needle in the horizontal position, perpendicular to the vertically oriented subcutaneous vascular layer. This sometimes results in extensive eyelid ecchymosis and edema, causing prolonged downtime. The purpose of this article is to present an alternative way of infiltrating local anesthesia into the upper eyelids, taking into account the anatomic orientation of the subcutaneous vascular layer. The authors present how infiltration is done with the needle oriented parallel to the vertically oriented blood vessels underneath the skin. Inadvertent injury to the subcutaneous vascular layer was avoided with parallel alignment of the needle. After a certain volume of anesthesia injection into the central portion, it is extended with a glass bar or a cotton swab to infiltrate the whole eyelid. In case of insufficient infiltration to the medial or lateral edge, one more injection is added in the same manner. This reduced intraoperative bleeding, postoperative ecchymosis, and hematoma formation. When magnification is needed during surgery, placing a drop of clear liquid over the blood vessel gives an enlarged view and makes injection of local anesthesia easier. The authors recommend orienting the needle parallel to the vertical subcutaneous vascular layer with droplet magnification to minimize the chance of injury and bleeding and to decrease the incidence of postoperative swelling.</p>","PeriodicalId":46810,"journal":{"name":"Saudi Journal of Ophthalmology","volume":"39 2","pages":"141-142"},"PeriodicalIF":0.6,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12240269/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144609940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rafah Fairaq, Lamees Alshaikh, Saud A Khan, Halah Bin Helayel, Ahmed Al Habash, Mohammed Almutlak
{"title":"Zonular compromise: A narrative review of indicators and management strategies.","authors":"Rafah Fairaq, Lamees Alshaikh, Saud A Khan, Halah Bin Helayel, Ahmed Al Habash, Mohammed Almutlak","doi":"10.4103/sjopt.sjopt_96_24","DOIUrl":"10.4103/sjopt.sjopt_96_24","url":null,"abstract":"<p><p>The reported prevalence of zonular weakness in the general population ranges between 0.46% and 2.6%. Several etiological risk factors are associated with zonular weakness, including increased age, pseudoexfoliation syndrome, Marfan syndrome, homocystinuria, retinitis pigmentosa mature cataracts, high axial myopia, and previous ocular trauma or surgery. Careful preoperative assessment or intraoperative recognition of the condition in the early steps of cataract surgery can aid in the prevention of complications and facilitate the management of the case. In this article, we summarized the available evidence to improve the surgery outcome and prevent complications. We mainly explored different approaches and instrumentation to preserve the lenticular capsule and aid in-the-bag intraocular lens implantation.</p>","PeriodicalId":46810,"journal":{"name":"Saudi Journal of Ophthalmology","volume":"39 4","pages":"354-360"},"PeriodicalIF":1.2,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12685262/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145716160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Analysis of topographic corneal parameters in a large cohort of corneal refractive surgery candidates.","authors":"Ahmed A Abdelghany, Ismail Omar","doi":"10.4103/sjopt.sjopt_237_24","DOIUrl":"10.4103/sjopt.sjopt_237_24","url":null,"abstract":"<p><strong>Purpose: </strong>Analysis of different corneal parameters in patients seeking corneal refractive surgery.</p><p><strong>Methods: </strong>Patients examined by Oculus Pentacam<sup>®</sup> HR from Oculus, Inc. at Roaa Laser <i>in situ</i> keratomileusis center, Minia, Egypt, during the period from July 1, 2023, to the end of December 2023 from both sexes between 18 and 45 years asking for corneal refractive surgery were reviewed. The following parameters were obtained and analyzed: K1 (Flat K)-K2 (Steep K)-K max-Pachymetry at corneal apex - Pachymetry at thinnest location - Distance between apex and thinnest location - Corneal back elevation - Topography shape - Keratoconus (If present). Patients with previous corneal surgery, intraocular surgery, or corneal opacity were excluded from the study.</p><p><strong>Results: </strong>The study included 5059 eyes of 2694 subjects; the mean age was 27.46 ± 7.04 (18-45) years, and most of them were of female gender, representing 1886 subjects (70.007%). The mean spherical equivalent was - 2.94 ± 3.68 diopters. The most common topographic shape was a symmetric bow tie in 2474 eyes (48.9%). Abnormal back elevation was reported in 19.4% of studied eyes and keratoconus in 4.1% of the studied eyes.</p><p><strong>Conclusion: </strong>Examination of refractive surgery candidates revealed that high myopia is frequent, the most frequent topographic shape is the symmetric bowtie, and keratoconus is infrequent, but abnormal back elevation had a higher percentage. Therefore, routine corneal examination by pentacam is recommended for these patients regardless of whether they are seeking refractive surgery or not. Our findings emphasize the importance of conservative pachymetry thresholds (≥500 µ) in regions with higher keratoconus risk. Future research should focus on longitudinal tracking of refractive surgery candidates to better understand the impact of subclinical ectasia markers on long-term outcomes.</p>","PeriodicalId":46810,"journal":{"name":"Saudi Journal of Ophthalmology","volume":"40 1","pages":"21-25"},"PeriodicalIF":1.1,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13082547/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147700351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nandini Bothra, Lisa Y Lin, Benjamin S Bleier, Suzanne K Freitag
{"title":"Multidisciplinary management of nasal and lacrimal drainage disorders in ectrodactyly-ectodermal dysplasia-clefting syndrome.","authors":"Nandini Bothra, Lisa Y Lin, Benjamin S Bleier, Suzanne K Freitag","doi":"10.4103/sjopt.sjopt_51_25","DOIUrl":"10.4103/sjopt.sjopt_51_25","url":null,"abstract":"<p><p>Ectrodactyly-ectodermal dysplasia-clefting syndrome (EECS) and its association with lacrimal drainage disorders are well known. EECS has p63 gene mutations which affect the ectodermal, orofacial, and limb development along with developmental delay affecting the entire body. Complex lacrimal drainage anomalies typically require endoscopic guidance through the nose for successful outcomes. p63 gene mutations affect the nasal structural development, making the surgical access as well as the outcomes in complex lacrimal drainage disorders difficult to predict and achieve. The present case describes a multidisciplinary approach of the oculoplastic and rhinology services in managing a complex lacrimal drainage disorder.</p>","PeriodicalId":46810,"journal":{"name":"Saudi Journal of Ophthalmology","volume":"39 3","pages":"278-280"},"PeriodicalIF":1.2,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12578411/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145432754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Multimodal imaging in a patient with sequential bilateral sarcoid intraretinal granuloma.","authors":"Wijden Nabi, Sana Khochtali, Molka Khairallah, Melek Kechida, Ilhem Mili, Bechir Jelliti, Nesrine Abroug, Moncef Khairallah","doi":"10.4103/sjopt.sjopt_221_24","DOIUrl":"10.4103/sjopt.sjopt_221_24","url":null,"abstract":"<p><p>A 24-year-old male patient with an unremarkable medical history presented with blurred vision in the right eye (RE) for a few weeks. The best-corrected visual acuity (BCVA) was 20/400 in the RE and 20/20 in the left eye (LE). Ophthalmic examination showed 3+ vitreous cells, snowballs, and multifocal segmental periphlebitis in both eyes. There was a one-disc diameter white lesion inferotemporal to the optic disc associated with hard exudates in the RE. Multimodal imaging findings were consistent with intraretinal granuloma. Workup led to the diagnosis of probable ocular sarcoidosis. Three years later, the patient developed an intraretinal granuloma involving the macula in the fellow eye. Intravitreal antivascular endothelial growth factor was given in association with anti-inflammatory therapy. Final BCVA was 20/200 in the RE and 20/1000 in the LE.</p>","PeriodicalId":46810,"journal":{"name":"Saudi Journal of Ophthalmology","volume":"40 3","pages":"305-309"},"PeriodicalIF":1.1,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13585357/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148991933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Through the eyes of an ocular immunologist: The interdisciplinary ophthalmology-rheumatology approach.","authors":"Emanuele Ragusa, Carlo Salvarani, Luca Cimino","doi":"10.4103/sjopt.sjopt_81_25","DOIUrl":"10.4103/sjopt.sjopt_81_25","url":null,"abstract":"","PeriodicalId":46810,"journal":{"name":"Saudi Journal of Ophthalmology","volume":"39 1","pages":"1-4"},"PeriodicalIF":0.6,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11964354/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A case of choroidal neovascularization following multiple repairs of a rhegmatogenous retinal detachment.","authors":"Dipen Kumar, Jason Zehden, Alice Y Zhang","doi":"10.4103/sjopt.sjopt_137_23","DOIUrl":"10.4103/sjopt.sjopt_137_23","url":null,"abstract":"<p><p>Choroidal neovascularization (CNV) is rare after retinal detachment (RD) surgery. In this retrospective report, we detail a case of CNV after three RD repairs with silicone oil placement for the repair of the most recent redetachment. The patient responded to antivascular endothelial growth factor intravitreal injections with resolution of intraretinal and subretinal fluid. Postoperative optical coherence tomography imaging may be required for patients with risk factors such as multiple surgeries on the same eye, silicone oil, or macular detachment.</p>","PeriodicalId":46810,"journal":{"name":"Saudi Journal of Ophthalmology","volume":"39 1","pages":"104-106"},"PeriodicalIF":0.6,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11964336/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ioannis Papasavvas, Abdulrahman F Albloushi, Masaru Takeuchi, Yoshihiko Usui, Sagnik Sen, Vania Lages, De-Kuang Hwang, Wen-Jung Lo, Marina Papadia, Carl P Herbort
{"title":"The potential harmfulness of consensus meetings and/or opinion surveys in medicine to determine nosological classifications: The \"white dots\" case.","authors":"Ioannis Papasavvas, Abdulrahman F Albloushi, Masaru Takeuchi, Yoshihiko Usui, Sagnik Sen, Vania Lages, De-Kuang Hwang, Wen-Jung Lo, Marina Papadia, Carl P Herbort","doi":"10.4103/sjopt.sjopt_331_24","DOIUrl":"10.4103/sjopt.sjopt_331_24","url":null,"abstract":"","PeriodicalId":46810,"journal":{"name":"Saudi Journal of Ophthalmology","volume":"39 1","pages":"110-111"},"PeriodicalIF":0.6,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11964338/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}