Analytical and Bioanalytical Chemistry最新文献

{"title":"Antibacterial Ag-PET flexible electrode via silver-mirror reaction with MOF Cu-BTC for sweat uric acid sensing.","authors":"Wenbo Li, Xiuxiu He, Xiang Hou, Xianpeng Gong, Jie Liu","doi":"10.1007/s00216-026-06751-4","DOIUrl":"https://doi.org/10.1007/s00216-026-06751-4","url":null,"abstract":"<p><p>Currently, wearable health monitors face challenges such as complex manufacturing processes, trade-offs between flexibility and performance, limited multimodal integration, and issues like low sensitivity, high detection limits, and susceptibility to interference. To address these issues, we present a high-performance, antibacterial wearable sweat sensor based on a flexible Ag/PET electrode fabricated via a silver mirror reaction. Surface pretreatment with carboxyl groups optimizes silver nanoparticle distribution, resulting in excellent conductivity, mechanical stability, and efficient 3D sweat collection. The electrode is further functionalized with Cu-BTC through electrochemical cathodic deposition. The constructed sensors demonstrate high sensitivity for uric acid (32.4 μA mM^-1 cm²) detection in artificial sweat (pH 5.5), with a wide linear range (10-300 μM), a low detection limit (1 μM), and strong anti-interference capability against common metabolites (the inhibition rate of over 62.3% and 75.5%). Moreover, the MOF-modified electrode exhibits significant antibacterial activity, achieving over 99% inhibition against Staphylococcus aureus and Escherichia coli through Ag⁺ release, thereby preventing bacterial contamination and ensuring long-term signal stability. The sensor is highly customizable via laser engraving and easily integrable, showing great potential for personalized healthcare and real-time sports monitoring. This work provides an innovative integrated strategy for advanced flexible electrochemical sensors, paving the way for the development of reliable smart wearable devices in health management.</p>","PeriodicalId":462,"journal":{"name":"Analytical and Bioanalytical Chemistry","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148910411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A novel approach for monitoring the spatial distribution and quantitative analysis of micronutrients in plant tissues using laser ablation ICP-MS imaging.","authors":"Olivia Doolan, Marta Peirats-Llobet, Mathew G Lewsey, Nicola Aberdein, Neil Bricklebank","doi":"10.1007/s00216-026-06780-z","DOIUrl":"https://doi.org/10.1007/s00216-026-06780-z","url":null,"abstract":"<p><p>Quantitative imaging of plant tissues by laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) is hindered by the lack of matrix-matched calibration standards. Established approaches, such as gelatine or homogenised tissue blocks, do not replicate plant matrices accurately. Here, we introduce a nano-dispenser-based calibration strategy that deposits nanolitre volumes of elemental standards directly onto paraffin-embedded grain sections, exploiting the low endogenous metal content of the endosperm to generate in situ calibration curves. Calibration performance for Mg, Mn, Cu, Zn, and Mo was assessed using LA-ICP-MS imaging and Iolite 4 data processing. The method demonstrated excellent linearity (R² > 0.98), reproducibility across multiple grains, and sub-ppm limits of detection. Comparative analysis with in-house homogenised blocks and NIST wheat reference material confirmed superior accuracy and reproducibility of the nano-dispenser approach. As a proof-of-concept, we have applied the method for the quantitative imaging of metals in a whole barley grain section, and the results show excellent agreement with published data obtained by conventional liquid-mode ICP MS. The technique reported here provides a robust, scalable, solution for quantitative metallomics studies of plant tissues, enabling improved assessment of nutrient distribution and supporting the development of standardised protocols for LA-ICP-MS imaging.</p>","PeriodicalId":462,"journal":{"name":"Analytical and Bioanalytical Chemistry","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148910459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Towards the digital analytical sciences in chemistry and biochemistry: from FAIR data ecosystems to artificial intelligence.","authors":"Darina Storozhuk, Jawad Kamran, Ravi Teja Vulchi, Rodrigo Escobar Díaz Guerrero, Thomas Bocklitz","doi":"10.1007/s00216-026-06781-y","DOIUrl":"https://doi.org/10.1007/s00216-026-06781-y","url":null,"abstract":"<p><p>The chemical and biochemical sciences are undergoing a profound digital transformation that is giving rise to the emerging paradigm of the digital analytical sciences, driven by an increasing need for research data digitalization, structuring, and standardization. This Trends article provides a bird's-eye view of how FAIR (Findable, Accessible, Interoperable, Reusable) data ecosystems are evolving from administrative guidelines into a critical enabler of modern analytical discovery. Because major advances in artificial intelligence (AI) depend fundamentally on structured and openly accessible scientific data, we discuss how the analytical sciences are now laying the corresponding infrastructural foundations needed to support the next generation of data-driven research. However, in domains such as biophotonics and advanced spectroscopy, large, comprehensively annotated experimental datasets remain limited, and algorithmic advances alone cannot fully compensate for data scarcity or poor standardization. To address this challenge, we examine the rapidly emerging field of physics-informed deep learning, in which physical laws and domain knowledge are incorporated directly into AI pipelines. By leveraging quantum-chemical simulations and transfer-matrix optics to generate synthetic pretraining data, these hybrid approaches can improve the robustness and generalizability of predictive models trained on limited experimental datasets. Finally, we discuss the emerging role of scientific representation learning and argue that realizing the full potential of AI in chemistry will require continued advances in hybrid algorithms alongside a sustained commitment to FAIR data governance and open scientific data infrastructures.</p>","PeriodicalId":462,"journal":{"name":"Analytical and Bioanalytical Chemistry","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148904862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recent advances in CRISPR/Cas12a-based biosensors for heavy metal analysis: a review of signal readout strategies and analytical performance.","authors":"Shanshan Hu, Jingxuan Liu, Jiahui Deng, Yanhui Yuan, Shuchang Peng, Mingxia Le, Jingxian Li, Kun Xu","doi":"10.1007/s00216-026-06786-7","DOIUrl":"https://doi.org/10.1007/s00216-026-06786-7","url":null,"abstract":"<p><p>Heavy metals are environmental hazards owing to their toxicity, persistence, and bioaccumulation in living organisms. These metals often accumulate or transform into more toxic compounds, and some accumulate in the human body through the food chain, which is extremely harmful to health. Although conventional detection methods are reliable, they are often hampered by high costs and complex operations, motivating the exploration of alternative sensing strategies. CRISPR/Cas (Clustering Regularly Interspaced Short Palindromic Repeats and Related Proteins) systems have shown potential for developing sensitive assays with significant target specificity, programmability, and signal amplification capabilities. This review discusses research progress on using CRISPR/Cas12a to detect and prevent heavy metal contamination in food. This review introduces methodological innovations in various signal readout methods, including fluorescence, colorimetry, electrochemistry, and microfluidics, and critically evaluates their analytical performance, such as sensitivity, selectivity, and practical applicability in complex food matrices. Finally, this review aims to provide valuable guidance for researchers to develop next-generation diagnostic tools that meet the requirements of rapid screening and precision testing for food safety.</p>","PeriodicalId":462,"journal":{"name":"Analytical and Bioanalytical Chemistry","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148899831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An excitation-customized ICT-type turn-on probe for visualization of cysteine fluctuation in diverse drug-induced ferroptosis pathways.","authors":"Yi-Jun Gong, Wenxue Shi, Aiying Ma, Qian Wang, Wenjuan Lou, Minglu Zhang","doi":"10.1007/s00216-026-06782-x","DOIUrl":"10.1007/s00216-026-06782-x","url":null,"abstract":"<p><p>Cysteine (Cys) acts as a key upstream regulator of cellular redox homeostasis and ferroptosis. Distinct ferroptosis inducers exert different effects on Cys metabolism. Erastin disrupts X_c^--dependent cystine uptake to deplete cellular Cys and trigger ferroptosis, while RSL3 induces ferroptosis by impairing downstream lipid metabolism without disturbing Cys homeostasis. Thus, real-time monitoring of Cys fluctuations is vital for distinguishing early ferroptosis initiation from downstream cascades. Conventional PET-type turn-on fluorescent probes suffer from high background and poor sensitivity. Herein, we report an excitation-customized strategy to develop ICT-type turn-on probe for Cys sensing. Based on a series of chalcogen-regulated near-infrared hemicyanine dyes, a selenium-substituted fluorophore HDXZ was screened out to construct the Cys-specific probe BXXZ. Under the customized excitation, BXXZ exhibited high fluorescence enhancement (66-fold), a low detection limit (0.23 μM), fast response, and excellent selectivity for Cys over Hcy and GSH. Benefiting from these merits, BXXZ enabled real-time visualization of differential Cys fluctuation in ferroptosis induced by erastin and RSL3, and achieved in situ tracking of intratumoral Cys fluctuation in HepG2 xenograft models. This work provides a feasible design strategy for high-quality ICT-type turn-on probes and a powerful imaging tool to explore the relationship between Cys homeostasis and ferroptosis.</p>","PeriodicalId":462,"journal":{"name":"Analytical and Bioanalytical Chemistry","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148896208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cold solvent washing enhances AFADESI-MSI spatial lipidomics and lipid metabolism profiling in pancreatic cancer.","authors":"Na Jiang, Qianlun Pu, Dan Du, Yangjuan Bai, Manjiangcuo Wang","doi":"10.1007/s00216-026-06795-6","DOIUrl":"https://doi.org/10.1007/s00216-026-06795-6","url":null,"abstract":"<p><p>In this study, we developed a cold solvent washing-enhanced AFADESI-MSI spatial lipidomics approach that improves detection sensitivity of tissue lipid metabolites while preserving molecular spatial distribution fidelity. Using brain tissue homogenate sections as benchmark samples, the solvent composition, washing temperature, and washing time were systematically optimized, with the optimal condition determined as methanol/water (8:2, v/v) treatment at -80 °C for 1 h. The optimized method yielded an average of more than 150 enhanced mass spectral peaks in mouse brain, kidney, and liver tissues, with significant signal enhancement. Molecular imaging of fine cerebellar structures (fiber tracts, ~60 μm) confirmed that lipid spatial fidelity was largely maintained. Clinical application to pancreatic cancer tissues revealed that PC and PE species were significantly upregulated in cancer tissues, with longer-chain PC species (e.g., PC 38:5, PC 40:7) showing preferential upregulation. Notably, PC 36:3 exhibited robust discriminatory power between cancer and distal margin tissues, demonstrating the broad tissue applicability of this method in revealing previously undetectable lipid spatial distributions and providing a novel analytical tool for lipid biomarker discovery in pancreatic cancer.</p>","PeriodicalId":462,"journal":{"name":"Analytical and Bioanalytical Chemistry","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148896170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis of molecularly imprinted polymers via core-shell magnetic mesoporous silicon-metal organic frameworks and their detection of three estrogens in traditional Chinese medicinal materials.","authors":"Lijuan Zhong, Jie Wen, Qing Zhou, Liwei Zheng, Haiyun Zhai","doi":"10.1007/s00216-026-06767-w","DOIUrl":"https://doi.org/10.1007/s00216-026-06767-w","url":null,"abstract":"<p><p>Steroidal estrogens are a type of compound that disrupts endocrine function and could potentially threaten food safety and human health. So, there is a real need for a sensitive and convenient method to detect estrogens in food samples. Magnetic silica (Fe₃O₄@SiO₂) has been recognized as a versatile adsorbent material with a porous structure that provides numerous imprinting sites while reducing mass transfer resistance, making it a promising candidate for adsorption applications. Fe₃O₄@SiO₂ denotes core-shell nanoparticles with magnetite as core and silica as outer shell. However, to further enhance the adsorption capacity and selectivity, the incorporation of metal-organic frameworks (MOFs) can be highly beneficial. In this work, estrogens were detected using molecularly imprinted polymers (MIPs) based on composites of Fe₃O₄@SiO₂ and aluminum metal-organic framework (Al-MOF). The Al-MOF, specifically MIL-68(Al), was selected for its high surface area, tunable pore size, and strong stability, which contribute to its excellent adsorption properties. The incorporation of MIL-68(Al) into the Fe₃O₄@SiO₂ matrix not only increases the available surface area but also provides additional specific binding sites for estrogens, resulting in enhanced selectivity and sensitivity. The resulting Fe₃O₄@SiO₂@MIL-68(Al)@MIP material proved to be a powerful adsorbent for estrogens with a maximum adsorption capacity of 34.52 mg g^-1. Notably, Fe₃O₄@SiO₂@MIL-68(Al)@MIP exhibited high adsorption capacity and selectivity and achieved a limit of detection (LOD) of 1.1-4.6 ng mL^-1 (0.04-0.18 µg kg^-1) and a linear response range of 40.96-8000 ng mL^-1, with recoveries between 87.34% and 99.86%, and relative standard deviations (RSDs) ≤ 5.92%. These impressive results are attributed to the synergistic effect of the magnetic core, porous silica shell, and high-affinity MOF, making the material a highly efficient sorbent for the pretreatment of estrogenic veterinary drugs in traditional Chinese medicine.</p>","PeriodicalId":462,"journal":{"name":"Analytical and Bioanalytical Chemistry","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148885958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A systematic approach for harmonisation of reference material (RM) production and analytical method development using Reference Matrix Materials (RMMs) combined with a database for reporting.","authors":"Håkan Emteborg, John Seghers, Andreas Breidbach, Robert Koeber","doi":"10.1007/s00216-026-06758-x","DOIUrl":"https://doi.org/10.1007/s00216-026-06758-x","url":null,"abstract":"<p><p>Analytical chemistry has changed profoundly over the last four decades with a tremendous expansion of analytical detection power. However, an increasing gap seems to exist between access to high-quality matrix Reference Materials and Certified Reference Materials (CRMs) and the sheer number of new analytes that can be determined in many matrices. The development of new RMs is moreover often connected with the use and development of novel measurement methods, especially in emerging fields of measurement. A challenge arises when characterising such RMs through interlaboratory comparisons, as it creates an RM/method causality dilemma, namely the production of new RMs require reliable and accurate methods, which in turn need good-quality RMs for method harmonisation and analytical quality assurance purposes. To overcome this dilemma, RM-producers must take iterative steps to gradually improve their candidate materials particularly with respect to homogeneity, which in turn allows improving the performance of the analytical methods. As both materials and methods evolve, they will eventually reach a point where target parameters can be certified in an appropriate matrix material. Provision of shared samples of specific matrices to a community of researchers could be a promising approach for future development of certified reference materials. This Trends article describes the components needed to establish such a resource and its expected outcomes. The core elements necessary for such a resource include (1) a material processing facility, (2) a storage and distribution centre, and (3) an online database for reporting measurement results. We propose the term Reference Matrix Materials (RMMs) for this category of samples. When multiple laboratories analyse RMMs, clusters of results eventually emerge in the database, tentatively providing a network of laboratories capable of performing specific measurements. Those results would subsequently become particularly valuable assets for RM-producers and proficiency testing providers. Method developers and analytical laboratories would also benefit from access to common materials enabling them to harmonise, compare, and evaluate the capabilities of different analytical methods. By providing such an anticipatory and dynamic platform, RM-producers and method developers can break open the closed circle of the RM/method causality dilemma. Such an approach could be a driver for faster, more universal, and efficient progress in the development of new RMs and analytical measurement methods alike.</p>","PeriodicalId":462,"journal":{"name":"Analytical and Bioanalytical Chemistry","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148890519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stripping voltammetric determination of zinc ions using a graphite-based electrochemical sensor modified with Alizarin Red S.","authors":"Maqsud Sayfiyev, Qudrat Boqiyev, Makhsuda Nazarova, Dilshod Ziyaev, Utkirjon Madatov, Charos Komilova, Gulnoza Boshbekova, Jasur Tursunqulov, Shakhboz Khasanov","doi":"10.1007/s00216-026-06770-1","DOIUrl":"https://doi.org/10.1007/s00216-026-06770-1","url":null,"abstract":"<p><p>A simple, low-cost, and sensitive electrochemical sensor was developed for the determination of zinc ions by anodic stripping voltammetry (ASV). The sensor (denoted G/W/ARS/MES) consists of a graphite-wax paste modified in situ with Alizarin Red S (ARS). The nature of the Zn-ARS interaction was examined by quantum-chemical calculations together with FT-IR and UV-Vis spectroscopy, which consistently indicated coordination of Zn(II) through the hydroxyl and carbonyl groups of ARS. Under optimised conditions-a universal buffer of pH 4.5-5.5, a 0.1 M H₃PO₄ + 0.1 M KNO₃ supporting electrolyte and an 80 s accumulation time-the modified sensor produced a well-resolved Zn(II) stripping peak at - 1040 mV, shifted by about 280 mV from that of the unmodified electrode and clearly separated from the signals of Cd(II), Pb(II), and Cu(II). The peak current varied linearly with concentration over the range 2.0-35.0 µg L^-1 (R² = 0.9910), with a detection limit of 0.57 µg L^-1. The method showed good repeatability and high selectivity and was applied to the determination of trace Zn(II) in waste, ground, and industrial-zone waters and in agricultural soils of the Jizzakh and Tashkent regions. The results agreed well with those obtained by atomic absorption spectrometry, confirming the accuracy of the proposed method.</p>","PeriodicalId":462,"journal":{"name":"Analytical and Bioanalytical Chemistry","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148885891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A luciferase immunoprecipitation system-based ultra-sensitive assay for HIV-1 p24 IgG in serum.","authors":"Yun Zhang, Xiane Guo, Yongsheng Chang, Maogang Chen, Yiming Tian, Tianjun Ni, Hongping Wei, Junping Yu","doi":"10.1007/s00216-026-06785-8","DOIUrl":"https://doi.org/10.1007/s00216-026-06785-8","url":null,"abstract":"<p><p>The human immunodeficiency virus type 1 (HIV-1) continues to pose a major global public health burden. However, progress in curbing the HIV pandemic is slowing, with the annual number of new infections remaining persistently high globally. HIV-1 p24 antigen-specific antibodies serve as the most consistent and robust markers for early HIV-1 seroconversion. Thus, the development of ultra-sensitive p24 IgG detection methods is of clinical and epidemiological significance. In this study, an assay for the detection of HIV p24-specific IgG in serum was established using the luciferase immunomagnetic system (LIMS), with the incorporation of a humanized Gaussia luciferase (hGLuc)-p24 chimeric antigen. Under optimized conditions, the assay enables semi-automated processing of 32 clinical serum samples within 15 min, with a minimal sample volume of only 2.5 μL per test. Compared to conventional enzyme-linked immunosorbent assay (ELISA), the HIV-1 p24 LIMS assay not only streamlines the experimental workflow but also exhibits superior sensitivity, a wider dynamic range for signal detection, and enhanced discrimination between positive and negative specimens. These integrated advantages render the assay particularly valuable for scenarios demanding rapid, accurate and high-throughput diagnostic responses to HIV-1 infection.</p>","PeriodicalId":462,"journal":{"name":"Analytical and Bioanalytical Chemistry","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148885929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}