Analytical and Bioanalytical Chemistry最新文献

Enzyme-induced fluorescence signal-on for specific detection of alkaline phosphatase and imaging in live cells. 酶诱导荧光信号的特异性检测碱性磷酸酶和成像在活细胞。

IF 3.8 2区化学

Analytical and Bioanalytical Chemistry Pub Date : 2025-07-14 DOI: 10.1007/s00216-025-06003-x

Zhifeng Wang, Yu Huang, Ke Pei, Tingting Feng

{"title":"Enzyme-induced fluorescence signal-on for specific detection of alkaline phosphatase and imaging in live cells.","authors":"Zhifeng Wang, Yu Huang, Ke Pei, Tingting Feng","doi":"10.1007/s00216-025-06003-x","DOIUrl":"https://doi.org/10.1007/s00216-025-06003-x","url":null,"abstract":"A highly sensitive and stable fluorescent strategy for detecting alkaline phosphatase (ALP) in complex samples was developed using oxidized single-walled carbon nanohorns (oxSWCNHs) and exonuclease I (Exo I). A ssDNA probe, comprising a fluorophore-labeled aptamer and a 3' phosphate group, was designed and synthesized. In the absence of ALP, the ssDNA probe binds to oxSWCNHs, causing fluorescence quenching. When ALP is present, it removes the 3' phosphate group from the ssDNA, releasing a free 3'-OH group. The dephosphorylated ssDNA is then hydrolyzed by Exo I, generating a single base and FAM, which cannot bind to oxSWCNHs, resulting in enhanced fluorescence of the system. This strategy was successfully applied to image hepatocytes, showing the potential of our sensing system for ALP bioimaging in living cells. The method has good selectivity and high sensitivity under optimized experimental conditions, with a detection limit of 0.4 mU/mL and a range of 0.5-50 mU/mL. Additionally, it was used to study the inhibitory effects of Na3VO4. This method has great potential for the quantitative detection of ALP in clinical diagnostics.","PeriodicalId":462,"journal":{"name":"Analytical and Bioanalytical Chemistry","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144625110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Characterizing cyanopeptides and transformation products in freshwater: integrating targeted, suspect, and non-targeted analysis with in silico modeling. 表征淡水中的氰肽和转化产物：整合目标，怀疑和非目标分析与硅模型。

IF 3.8 2区化学

Analytical and Bioanalytical Chemistry Pub Date : 2025-07-12 DOI: 10.1007/s00216-025-05999-6

Audrey Roy-Lachapelle, Morgan Solliec, Christian Gagnon

{"title":"Characterizing cyanopeptides and transformation products in freshwater: integrating targeted, suspect, and non-targeted analysis with in silico modeling.","authors":"Audrey Roy-Lachapelle, Morgan Solliec, Christian Gagnon","doi":"10.1007/s00216-025-05999-6","DOIUrl":"https://doi.org/10.1007/s00216-025-05999-6","url":null,"abstract":"Harmful algal blooms (HABs) pose significant risks to environmental and public health, primarily through cyanotoxin production. Influenced by anthropogenic and climatic factors, cyanobacteria require advanced methods for identifying and characterizing their secondary metabolites. This study presents a multi-step approach to investigate the most abundant cyanopeptides in freshwater samples from agricultural and urban areas, aiming to improve their characterization and understand their environmental fate. A targeted method was developed to quantify 28 cyanopeptides across seven families, being one of the most extensive quantitative analyses of cyanopeptides. Significant concentrations of 14 congeners were detected, ranging from 0.038 to 5.68 µg L-1. A suspect screening method was developed and applied to expand detection, integrating CyanoMetDB and in silico modeling for the prediction of molecular features, increasing confidence in characterization. This approach enabled the identification of 26 uncommon cyanopeptides, including the newly characterized [DMAdda5, GluOMe6]microcystin-LHty. Additionally, a novel non-targeted analysis method was developed, combining compound class search, in silico modeling, and the enviPath UG & Co KG biotransformation prediction tool. This new strategy led to the identification of seven new transformation products and potential microcystins, including a new dopamine-modified microcystin-YR and the new linear [seco-1/7][Asp3]microcystin-LR. By integrating targeted, suspect, and non-targeted approaches, this study significantly enhanced cyanopeptide detection and characterization, providing valuable insights for environmental monitoring and public health protection.","PeriodicalId":462,"journal":{"name":"Analytical and Bioanalytical Chemistry","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144615700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pentameric nanobodies serve as a capture agent and RANbodies function as immunoprobes for the sensitive detection of Salmonella typhimurium in immunoassays. 在免疫分析中，五聚体纳米体作为捕获剂，ranbody作为免疫探针用于鼠伤寒沙门菌的敏感检测。

IF 3.8 2区化学

Analytical and Bioanalytical Chemistry Pub Date : 2025-07-10 DOI: 10.1007/s00216-025-05973-2

Yuan Weng, Ming Yang, Yunmin Wang, Qiang Xu, Miwan Shi, Aomo Tan, Peiling Yuan, Changwei Lei, Kui Gu

引用次数: 0

Microwave-assisted synthesis of hyper-crosslinked polymer composite alginate hydrogel sorbent for dispersive solid-phase extraction of phthalate esters leached from PET and LDPE. 微波辅助合成超交联聚合物复合海藻酸盐水凝胶吸附剂分散固相萃取PET和LDPE浸出的邻苯二甲酸酯。

IF 3.8 2区化学

Analytical and Bioanalytical Chemistry Pub Date : 2025-07-10 DOI: 10.1007/s00216-025-06001-z

Patamawadee Phalipat, Opas Bunkoed, Maria Llompart, Peerada Pakdeepin, Piyaluk Nurerk

{"title":"Microwave-assisted synthesis of hyper-crosslinked polymer composite alginate hydrogel sorbent for dispersive solid-phase extraction of phthalate esters leached from PET and LDPE.","authors":"Patamawadee Phalipat, Opas Bunkoed, Maria Llompart, Peerada Pakdeepin, Piyaluk Nurerk","doi":"10.1007/s00216-025-06001-z","DOIUrl":"https://doi.org/10.1007/s00216-025-06001-z","url":null,"abstract":"A hyper-crosslinked polymer composite alginate hydrogel was developed as a sorbent for dispersive solid-phase extraction of phthalate esters. The hyper-crosslinked polymer was synthesized via microwave-assisted polymerization and subsequently embedded into the alginate hydrogel sorbent. Four extracted target analytes were quantified using high-performance liquid chromatography coupled with diode array detection. The method demonstrated good linearity with R2 values exceeding 0.999 for all analytes. The linear ranges were 0.20 to 200 µg L-1 for benzyl butyl phthalate and 0.5 to 200 µg L⁻1 for dibutyl phthalate, di-2-ethylhexyl phthalate, and di-n-octyl phthalate. Limits of detection ranged from 0.05 to 0.15 µg L-1, while limits of quantification ranged from 0.20 to 0.50 µg L-1. The method exhibited high precision with intra-day and inter-day relative standard deviations (RSDs) between 1.1-3.2% and 1.7-3.7%, respectively. The sorbent showed good reproducibility with RSDs in the range of 0.9 to 4.9% and reusability for up to 11 cycles of adsorption-desorption. The efficiency of the method was comparable with that of a commercial cartridge. Recoveries of phthalate esters from drinking water and artificial tear samples ranged from 90.0 to 100.6%. The developed method was efficient and reliable for the analysis of phthalate esters.","PeriodicalId":462,"journal":{"name":"Analytical and Bioanalytical Chemistry","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144599026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Programmable DNA aptamer logic gates: from structural design to integrated systems for intelligent nanoscale biosensors. 可编程DNA适体逻辑门：从结构设计到集成系统的智能纳米级生物传感器。

IF 3.8 2区化学

Analytical and Bioanalytical Chemistry Pub Date : 2025-07-10 DOI: 10.1007/s00216-025-05982-1

Precious Asumadu, Zhuowen Guo, Shuo Qi, Chang Liu, Yaqi Li, Qiaoqiao Shi, Dezhao Kong, Hua Ye, Caili Fu, Zhouping Wang

{"title":"Programmable DNA aptamer logic gates: from structural design to integrated systems for intelligent nanoscale biosensors.","authors":"Precious Asumadu, Zhuowen Guo, Shuo Qi, Chang Liu, Yaqi Li, Qiaoqiao Shi, Dezhao Kong, Hua Ye, Caili Fu, Zhouping Wang","doi":"10.1007/s00216-025-05982-1","DOIUrl":"https://doi.org/10.1007/s00216-025-05982-1","url":null,"abstract":"DNA aptamer-based logic gates represent significant advances in molecular computing, enabling complex biological computations at the nanoscale. These systems leverage the unique programmable properties of DNA aptamers-short, single-stranded oligonucleotides with high specificity and binding affinity for diverse applications across fields such as clinical diagnostics, food/environmental monitoring, and targeted therapeutic delivery, garnering significant research interest in the past few decades. In this review, we first expand on the fundamentals of aptamers, including its SELEX process and post-SELEX modifications. We systematically examine the design principles and operation mechanisms of DNA aptamer-based logic gates, mainly AND, OR, INHIBIT and NOT as reported by researchers. Then, we highlight various logic gates based on different oligonucleotides spanning from intact and split aptamers to DNA origami architectures, DNA nanorobots, and G-quadruplex structural switches, bringing to light their applications across various fields. Recent innovations in multi-input/output gate cascades, CRISPR-Cas-integrated systems and signal amplification approaches are highlighted as key developments in DNA aptamer-based logic gates. Finally, we elucidate challenges relating to DNA aptamer-based systems such as aptamer performance, cross-reactivity in complex multi-input systems and the complexities of merging other systems to amplify output readability, among others, to the end that in addressing these challenges, we will be able to unlock the full potential of this system.","PeriodicalId":462,"journal":{"name":"Analytical and Bioanalytical Chemistry","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144599028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Liquid chromatography-mass spectrometry approach for characterizing sucrose isomers in complex mono-floral honey. 液相色谱-质谱法测定复合单花蜂蜜中蔗糖异构体。

IF 3.8 2区化学

Analytical and Bioanalytical Chemistry Pub Date : 2025-07-09 DOI: 10.1007/s00216-025-05988-9

Enoch Amoah, Santosh Raman Acharya, Ayesha Seth, Abraham K Badu-Tawiah

{"title":"Liquid chromatography-mass spectrometry approach for characterizing sucrose isomers in complex mono-floral honey.","authors":"Enoch Amoah, Santosh Raman Acharya, Ayesha Seth, Abraham K Badu-Tawiah","doi":"10.1007/s00216-025-05988-9","DOIUrl":"https://doi.org/10.1007/s00216-025-05988-9","url":null,"abstract":"Sucrose, which forms < 2% of the chemical content in honey samples, is known to have five structural isomers each with its own medicinal benefits. Unfortunately, studies characterizing the specific sucrose isomer(s) present in honey samples are limited. Herein, we introduce a contained electrospray ionization (cESI) method that can be coupled between liquid chromatography (LC) and tandem mass spectrometry (MS/MS). This LC-cESI-MS/MS platform leverages chloride adduction to enable sensitive differentiation and characterization of disaccharide isomers in complex honey samples. By integrating retention time and collision-induced dissociation (CID) MS/MS data, we achieved orthogonal analysis of six sucrose isomers. The MS/MS on the chloride adducts showed distinct fragment ions for each isomer. Additional optimization afforded nanomolar (nM) detection limits for all disaccharides analyzed via chloride adduction in negative-ion mode, a feature that showed superior sensitivity compared with conventional sodium adduction methods typically achieved in positive-ion mode. We identified four sucrose isomers (turanose, palatinose, maltulose, and trehalulose) in three mono-floral honey samples, of which turanose was the most abundant isomer. Sucrose itself could not be confirmed in any of the honey samples tested and leucrose was confirmed to be absent. Although the specific amounts of these isomers were not determined, principal component analysis showed that the abundances of the four identified structural isomers significantly differed in the three mono-floral honey samples. The current study forms the first report suggesting turanose to be the main sucrose isomer in the tested mono-floral honey. Such identification was made possible because of our ability to independently optimize LC and cESI spray solvents, and to enable online microdroplet chemistry via chloride adduction, which allowed the conventional CID-MS/MS to yield highly informative fragmentation.","PeriodicalId":462,"journal":{"name":"Analytical and Bioanalytical Chemistry","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144590151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quantification of poly(ethylene terephthalate) in environmental samples after methanolysis via gas chromatography-mass spectrometry. 气相色谱-质谱联用法测定甲醇分解后环境样品中的聚对苯二甲酸乙酯。

IF 3.8 2区化学

Analytical and Bioanalytical Chemistry Pub Date : 2025-07-09 DOI: 10.1007/s00216-025-05963-4

Tim Lauschke, Ann-Christin Merfels, Thomas A Ternes, Georg Dierkes

{"title":"Quantification of poly(ethylene terephthalate) in environmental samples after methanolysis via gas chromatography-mass spectrometry.","authors":"Tim Lauschke, Ann-Christin Merfels, Thomas A Ternes, Georg Dierkes","doi":"10.1007/s00216-025-05963-4","DOIUrl":"https://doi.org/10.1007/s00216-025-05963-4","url":null,"abstract":"Quantification of the polyester poly(ethylene terephthalate) (PET) in environmental samples is a particular challenge. Due to strong matrix effects by inorganic compounds, thermoanalytical methods are not recommendable for a precise quantification of PET in complex environmental matrices. It was shown that depolymerization followed by determination of chemolysis products is a good alternative. In this study, we developed a quantification method for PET based on methanolysis to terephthalic acid dimethyl ester using sodium methoxide as a catalyst, and subsequent determination via GC-MS. With poly(ethylene terephthalate-d4), we introduce a new internal standard covering the whole analytical process. Satisfactory detection and quantifications limits (1 and 4 µg g-1) as well as recoveries of 87-117% were achieved. Tests with various PET-free natural compounds exhibited no interfering matrix effects. The newly developed method was applied for MP quantification in a variety of environmental samples such as sediments, sewage sludge, indoor dust, and water. In all these matrices, PET was present. Highest concentrations were detected in indoor dust with up to 57 mg/g. In bottled water, PET concentrations were detected as high as 463 ng/L. The described depolymerization method offers a straightforward approach for a reliable quantification of PET in complex environmental matrices suitable for routine analysis.","PeriodicalId":462,"journal":{"name":"Analytical and Bioanalytical Chemistry","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144590154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

On the question of correct use of replicates in quantitative label-free proteomics. 关于定量无标记蛋白质组学中正确使用重复的问题。

IF 3.8 2区化学

Analytical and Bioanalytical Chemistry Pub Date : 2025-07-09 DOI: 10.1007/s00216-025-05992-z

Leyla A Garibova, Mikhail V Gorshkov, Mark V Ivanov

{"title":"On the question of correct use of replicates in quantitative label-free proteomics.","authors":"Leyla A Garibova, Mikhail V Gorshkov, Mark V Ivanov","doi":"10.1007/s00216-025-05992-z","DOIUrl":"https://doi.org/10.1007/s00216-025-05992-z","url":null,"abstract":"Label-free quantitation is the most popular method in proteomics for assessing changes in protein concentrations. However, practical aspects like the optimal use of technical replicates, the impact of removing low-identified protein runs, and the effect of combining information from technical replicates for subsequent differential expression analysis remain debated. This study utilized five LFQ workflows: MaxQuant + Perseus, FragPipe + MSstats, Proteome Discoverer, DirectMS1Quant, and IdentiPy + IQMMA. Previously published data sets acquired for three-species proteomes using Orbitrap FTMS consisted of spikes of Escherichia coli, yeast, and human lysates with known concentration changes that were used for benchmarking the workflows. All tested workflows gave fairly similar results in terms of the number of differentially expressed proteins (DEPs) and quantitative false discovery rate (FDR). Adding more technical replicates either increased the number of DEPs or decreased the FDR, depending on the workflow. Eliminating runs with the lowest number of protein identifications led to an increase in the number of DEPs, but at the cost of elevated FDR, thus reducing the accuracy and precision of protein fold change estimations. The Match-Between-Runs option provides additional DEPs and does not increase empirical FDR in most methods. We found that the selected set of proteomics workflows turned out to be different in answering the practical questions raised above, even for the simple artificial benchmark data set. Our results should serve as a starting point and encourage researchers to more thoroughly test their own approaches in real-world problems.","PeriodicalId":462,"journal":{"name":"Analytical and Bioanalytical Chemistry","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144590152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthetic spectral libraries for Raman model calibration. 用于拉曼模型校准的合成光谱库。

IF 3.8 2区化学

Analytical and Bioanalytical Chemistry Pub Date : 2025-07-08 DOI: 10.1007/s00216-025-05985-y

Louis V Hellequin, Vicent J Borràs, Patrick Romann, Nandita Vishwanathan, Jonathan Souquet, Thomas K Villiger

{"title":"Synthetic spectral libraries for Raman model calibration.","authors":"Louis V Hellequin, Vicent J Borràs, Patrick Romann, Nandita Vishwanathan, Jonathan Souquet, Thomas K Villiger","doi":"10.1007/s00216-025-05985-y","DOIUrl":"https://doi.org/10.1007/s00216-025-05985-y","url":null,"abstract":"Raman spectroscopy has become increasingly popular in the process analytical technology (PAT) landscape due to its versatility and predictive capability in bioprocesses. However, model building remains a time-consuming and cost-intensive task. Building upon a fast calibration workflow based on physical pure compounds spiking in water, this work explores the novel use of in silico spiking of pure spectral fingerprints of various analytes. Through data fusion, a synthetic spectral library (SSL) is created that combines base spectra information from mammalian cell culture runs with matrix variability, as well as pure component spectra in water, aiming to greatly reduce the cost and time required for efficient model building. The findings indicate that the in silico addition of pure compounds provides spectral information comparable to physically spiked measurements. Consequently, this approach allows for the generation of an extensive number of information-rich spectra, forming a robust foundation for various regression algorithms and enhancing Raman calibration of existing spectral databases.","PeriodicalId":462,"journal":{"name":"Analytical and Bioanalytical Chemistry","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144590155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Automated thermal desorption-gas chromatography/mass spectrometry for screening of hazardous chemicals in cotton and cotton blend garments-analytical challenges. 自动热解吸-气相色谱/质谱法筛选棉和棉混纺服装中的危险化学品-分析挑战。

IF 3.8 2区化学

Analytical and Bioanalytical Chemistry Pub Date : 2025-07-08 DOI: 10.1007/s00216-025-05993-y

Tim Åström, Conny Östman, Ioannis Sadiktsis, Maria-Ximena Ruiz-Caldas, Ulrika Nilsson

{"title":"Automated thermal desorption-gas chromatography/mass spectrometry for screening of hazardous chemicals in cotton and cotton blend garments-analytical challenges.","authors":"Tim Åström, Conny Östman, Ioannis Sadiktsis, Maria-Ximena Ruiz-Caldas, Ulrika Nilsson","doi":"10.1007/s00216-025-05993-y","DOIUrl":"https://doi.org/10.1007/s00216-025-05993-y","url":null,"abstract":"The global production of textiles involves large amounts of health-hazardous chemicals, constituting possible health risks since residues usually remain in the finished garments. In the present study, a recently published ATD-GC/MS methodology for screening synthetic textiles is further extended to cotton and cotton blend materials. Different textile materials with a high content of cotton were found to exhibit large variations in adsorption strength for a number of chemicals frequently detected in textiles. This was shown to strongly influence the thermal desorption efficiency in ATD-GC/MS. By using absolute response factors from appropriate internal standards spiked directly onto the textile samples, the effects from these differences could be minimized. In this way, accurate quantification was made possible regardless of textile composition, and quantification of native textile chemicals in garments made with the ATD-GC/MS method agreed well with an offline method based on solvent extraction and GC/MS analysis. The ATD-GC/MS method has now been shown to be applicable for quantitative screening of at least 75% of all the clothing textiles on the retail market. The simplified quantification method makes it suitable for screening large numbers of samples. For all fiber materials investigated, the method limit of detection, using only 20 mg of textile, is at least 100 times lower than the current EU regulation for quinoline and a number of toxic arylamines.","PeriodicalId":462,"journal":{"name":"Analytical and Bioanalytical Chemistry","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144590150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0