Md Nurul Amin, A K M Rezaur Rahman, Muhammad Asif Zubair, Quazi Muhammad Rashed Nizam
{"title":"Quantitative assessment of <sup>167</sup>Tm isotope production: experimental data analysis and model validation.","authors":"Md Nurul Amin, A K M Rezaur Rahman, Muhammad Asif Zubair, Quazi Muhammad Rashed Nizam","doi":"10.1007/s12194-024-00862-2","DOIUrl":"https://doi.org/10.1007/s12194-024-00862-2","url":null,"abstract":"<p><p><sup>167</sup>Tm is an effective radioisotope for use in theragnostic purposes. This study aims to find the best alternative routes for producing <sup>167</sup>Tm for appropriate cancer therapy and diagnostics. In this study, we comprehensively analyzed production cross-sections of <sup>167</sup>Tm and investigated the behavior of these reactions using six different level density models and refined optical model potential (OMP) parameters with the nuclear reaction code TALYS 1.96. Using this code, we estimated the specific activity and production yield for promising production routes. For characterizing the <sup>167</sup>Tm isotopes, the energy distribution of <sup>167</sup>Tm was also analyzed for each prominent reaction by particle and heavy ion transport code system (PHITS). The maximum specific activity was estimated as 52.6-75.2 GBq/g with a production yield of 20.2-32.7 GBq/mAh for the route <sup>169</sup>Tm(p,x)<sup>167</sup>Tm. The experimental value was reproduced with good agreement by TALYS adjusting different OMP parameters. <sup>169</sup>Tm(p,x)<sup>167</sup>Tm is the alternative route for producing <sup>167</sup>Tm, for which TALYS can reproduce the result more accurately.</p>","PeriodicalId":46252,"journal":{"name":"Radiological Physics and Technology","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142792648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Optimizing the planning process in computed tomography-based image-guided adaptive brachytherapy for cervical cancer using a spreadsheet-based daily dose management system.","authors":"Jun Takatsu, Takahito Chiba, Naoya Murakami, Kotaro Iijima, Tatsuya Inoue, Noriyuki Okonogi, Yoichi Muramoto, Terufumi Kawamoto, Tatsuki Karino, Hiroyuki Okamoto, Satoshi Nakamura, Hiroki Nakayama, Yasuhisa Terao, Naoto Shikama","doi":"10.1007/s12194-024-00867-x","DOIUrl":"https://doi.org/10.1007/s12194-024-00867-x","url":null,"abstract":"<p><p>This study developed a system to reduce the treatment planning time for cervical cancer brachytherapy. An in-house Excel spreadsheet was developed to streamline dosimetric evaluation by combining external beam radiotherapy and brachytherapy doses, while also displaying daily dose constraints, a novel feature of the system. This system was validated in 46 consecutive patients who underwent intracavitary and interstitial brachytherapy using several applicators and required more complex dose calculation procedures than intracavitary brachytherapy alone. The proposed system included contouring and catheter reconstruction using multiple treatment planning systems simultaneously and was integrated with Excel spreadsheets for rapid dosimetric evaluation. The median time required for treatment planning was 36 min (range: 12-72 min), which was a much shorter time than those reported previously. This optimized system demonstrated the potential to increase the efficiency of brachytherapy planning to meet prescribed dose constraints without compromising treatment quality.</p>","PeriodicalId":46252,"journal":{"name":"Radiological Physics and Technology","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142787310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Behzad Aminafshar, Hamid Reza Baghani, Ali Asghar Mowlavi
{"title":"Tuning the range-energy relationship parameter for Monte Carlo-based proton Bragg curve spreading in muscle, bone, and polymethylmethacrylate.","authors":"Behzad Aminafshar, Hamid Reza Baghani, Ali Asghar Mowlavi","doi":"10.1007/s12194-024-00864-0","DOIUrl":"https://doi.org/10.1007/s12194-024-00864-0","url":null,"abstract":"<p><p>Determination of spread-out Bragg peak (SOBP) inside media other than water is important for research or clinical purposes. Current study aims to characterize the optimal \"p\" values needed for the simulation of proton SOBP inside some dosimetry media using MCNPX Monte Carlo code. Following the provided data by ICRU-49 and applying the Bortfeld and Jette recommendations, the \"p\" values were determined for muscle, compact bone, and PMMA. Then, \"p\" values were optimized to reach accurate weight fractions for the Monte Carlo simulation of SOBP curves. Obtained optimal \"p\" values can produce accurate proton weight fractions for flat SOBP simulation. The slope of the SOBP region was highly dependent on the \"p\" value, so small changes in this parameter can largely tilt up or down the SOBP. The tabulated optimal \"p\" values can be reliably used for proton weight fraction determination during the Monte Carlo simulation of the proton beam SOBP curve inside the investigated media.</p>","PeriodicalId":46252,"journal":{"name":"Radiological Physics and Technology","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142787372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mayu Sakai, Toshioh Fujibuchi, Hyojin Lee, Donghee Han
{"title":"Imaging of scattered radiation sources in X-ray radiography using a semiconductor radiation visualization camera.","authors":"Mayu Sakai, Toshioh Fujibuchi, Hyojin Lee, Donghee Han","doi":"10.1007/s12194-024-00865-z","DOIUrl":"https://doi.org/10.1007/s12194-024-00865-z","url":null,"abstract":"<p><p>The objective of this study is to verify whether X-ray can be visualized for imaging scattered radiation sources in X-ray radiography using a semiconductor radiation visualization camera with image processing and to evaluate its characteristics. Measurements were performed using a C-arm X-ray fluoroscopy device with a portable radiation visualization camera. The height of the radiation protective board and size of the irradiation field were the conditions that were varied during X-ray radiography. Based on the data obtained from the radiation visualization camera, output images were created displaying the intensity of the scattered radiation in color, which were then superimposed on the images captured with an optical camera. The scattered radiation generated by the phantom and within the X-ray tube were confirmed. These results indicate the feasibility of using this radiation visualization camera for imaging.</p>","PeriodicalId":46252,"journal":{"name":"Radiological Physics and Technology","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142787282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M Muranaka, M Sakai, T Ogano, Y Hoshino, M Nakao, K Yusa, T Suto, T Ohno
{"title":"Evaluation of stopping power ratio of artificial breast implants for carbon-ion radiotherapy.","authors":"M Muranaka, M Sakai, T Ogano, Y Hoshino, M Nakao, K Yusa, T Suto, T Ohno","doi":"10.1007/s12194-024-00860-4","DOIUrl":"https://doi.org/10.1007/s12194-024-00860-4","url":null,"abstract":"<p><p>The number of patients requiring breast reconstruction with artificial implants has been increasing, and so is the use of carbon-ion radiotherapy (CIRT). Consequently, a growing number of patients with artificial breast implants are expected to undergo CIRT. Because artificial breasts are composed of a silicone polymer gel with a silicon-oxygen backbone, which differs significantly from human tissues, the stopping power ratio for carbon beams cannot be accurately converted from CT values using standard CT-to-stopping power ratio tables (CT-SP tables). Incorrect stopping power ratios can lead to significant problems in CIRT, including erroneous calculations of carbon beam range. To address this, we measured the CT values and stopping power ratios of three commercial artificial breasts using a 380 MeV/u carbon beam. Our results revealed significant deviations from the CT-SP table values. For instance, calculations for treating lung cancer with incorrect stopping power ratios resulted in errors of approximately 5 mm in range calculations, adversely affecting dose distribution to the target. Although further studies with various products are needed, it is crucial to conduct thorough patient consultations and develop treatment plans using accurate stopping power ratios.</p>","PeriodicalId":46252,"journal":{"name":"Radiological Physics and Technology","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142773518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Can bile excretion on Gd-EOB-MRI be used as a visual criterion for the hepatobiliary phase?","authors":"Masafumi Nakamura, Yasuo Takatsu, Mutsumi Yoshizawa, Satoshi Kobayashi, Tosiaki Miyati","doi":"10.1007/s12194-024-00868-w","DOIUrl":"https://doi.org/10.1007/s12194-024-00868-w","url":null,"abstract":"<p><p>To determine whether visually observed biliary excretion of gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid (Gd-EOB-DTPA) can be used to assess contrast adequacy of hepatobiliary phase (HBP) images. Images of 121 patients undergoing Gd-EOB-DTPA-enhanced magnetic resonance imaging were used. Adequate HBP images were defined as a quantitative liver-spleen contrast ratio (Q-LSC) ≥ 1.5. Visual evaluation was performed to determine if an adequate HBP image could be obtained based on the presence or absence of bile excretion. Common bile duct-paravertebral contrast (CPC) was used to assess the degree of bile excretion, the albumin-bilirubin (ALBI) grade was used to assess liver reserve, and the Q-LSC was used to assess HBP image contrast. The results were used to quantitatively evaluate the relationships of the degree of bile excretion with HBP image contrast and liver reserve. The cases correctly determined by visual evaluation via bile excretion were 80 (66.1%) at HBP 10 min after injection and 89 (73.6%) at HBP 20 min after injection. Among cases with Q-LSC ≥ 1.5 indicating bile excretion, there were 33 cases at HBP 10 min after injection and 86 cases at HBP 20 min after injection. Furthermore, among cases with Q-LSC < 1.5, indicating no bile excretion, there were 47 cases at HBP 10 min after injection and 3 cases at HBP 20 min after injection. Visually observed biliary excretion of Gd-EOB-DTPA is not a criterion for adequate HBP image contrast.</p>","PeriodicalId":46252,"journal":{"name":"Radiological Physics and Technology","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142773423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Assessing knowledge about medical physics in language-generative AI with large language model: using the medical physicist exam.","authors":"Noriyuki Kadoya, Kazuhiro Arai, Shohei Tanaka, Yuto Kimura, Ryota Tozuka, Keisuke Yasui, Naoki Hayashi, Yoshiyuki Katsuta, Haruna Takahashi, Koki Inoue, Keiichi Jingu","doi":"10.1007/s12194-024-00838-2","DOIUrl":"10.1007/s12194-024-00838-2","url":null,"abstract":"<p><p>This study aimed to evaluate the performance for answering the Japanese medical physicist examination and providing the benchmark of knowledge about medical physics in language-generative AI with large language model. We used questions from Japan's 2018, 2019, 2020, 2021 and 2022 medical physicist board examinations, which covered various question types, including multiple-choice questions, and mainly focused on general medicine and medical physics. ChatGPT-3.5 and ChatGPT-4.0 (OpenAI) were used. We compared the AI-based answers with the correct ones. The average accuracy rates were 42.2 ± 2.5% (ChatGPT-3.5) and 72.7 ± 2.6% (ChatGPT-4), showing that ChatGPT-4 was more accurate than ChatGPT-3.5 [all categories (except for radiation-related laws and recommendations/medical ethics): p value < 0.05]. Even with the ChatGPT model with higher accuracy, the accuracy rates were less than 60% in two categories; radiation metrology (55.6%), and radiation-related laws and recommendations/medical ethics (40.0%). These data provide the benchmark for knowledge about medical physics in ChatGPT and can be utilized as basic data for the development of various medical physics tools using ChatGPT (e.g., radiation therapy support tools with Japanese input).</p>","PeriodicalId":46252,"journal":{"name":"Radiological Physics and Technology","volume":" ","pages":"929-937"},"PeriodicalIF":1.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142298277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of calculation accuracy and computation time in a commercial treatment planning system for accelerator-based boron neutron capture therapy.","authors":"Akihiko Takeuchi, Katsumi Hirose, Ryohei Kato, Shinya Komori, Mariko Sato, Tomoaki Motoyanagi, Yuhei Yamazaki, Yuki Narita, Yoshihiro Takai, Takahiro Kato","doi":"10.1007/s12194-024-00833-7","DOIUrl":"10.1007/s12194-024-00833-7","url":null,"abstract":"<p><p>This study aims to evaluate the feasibility of using a commercially available boron neutron capture therapy (BNCT) dose calculation program (NeuCure<sup>®</sup> Dose Engine) in terms of calculation accuracy and computation time. Treatment planning was simulated under the following calculation parameters: 1.5-5.0 mm grid sizes and 1-10% statistical uncertainties. The calculated monitor units (MUs) and computation times were evaluated. The MUs calculated on grid sizes larger than 2 mm were overestimated by 2% compared with the result of 1.5 mm grid. We established the two-step method for the routine administration of BNCT: multiple calculations involved in beam optimization should be done at a 5 mm grid and a 10% statistical uncertainty (the shortest computation time: 10.3 ± 2.1 min) in the first-step, and final dose calculations should be performed at a 2 mm grid and a 10% statistical uncertainty (satisfied clinical accuracy: 6.9 ± 0.3 h) in the second-step.</p>","PeriodicalId":46252,"journal":{"name":"Radiological Physics and Technology","volume":" ","pages":"907-917"},"PeriodicalIF":1.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141976920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"LIT-Unet: a lightweight and effective model for medical image segmentation.","authors":"Ru Wang, Qiqi Kou, Lina Dou","doi":"10.1007/s12194-024-00844-4","DOIUrl":"10.1007/s12194-024-00844-4","url":null,"abstract":"<p><p>This study aimed to design a simple and efficient automatic segmentation model for medical images, so as to facilitate doctors to make more accurate diagnosis and treatment plan. A hybrid lightweight network LIT-Unet with symmetric encoder-decoder U-shaped architecture is proposed. Synapse multi-organ segmentation dataset and automated cardiac diagnosis challenge (ACDC) dataset were used to test the segmentation performance of the method. Two indexes, Dice similarity coefficient (DSC ↑) and 95% Hausdorff distance (HD95 ↓), were used to evaluate and compare the segmentation ability with the current advanced methods. Ablation experiments were conducted to demonstrate the lightweight nature and effectiveness of our model. For Synapse dataset, our model achieves a higher DSC score (80.40%), an improvement of 3.8% over the typical hybrid model (TransUnet). The 95 HD value is low at 20.67%. For ACDC dataset, LIT-Unet achieves the optimal average DSC (%) of 91.84 compared with other networks listed. Compared to patch expanding, the DSC of our model is intuitively improved by 1.62% with the help of deformable token merging (DTM). These results show that the proposed hierarchical LIT-Unet can achieve significant accuracy and is expected to provide a reliable basis for clinical diagnosis and treatment.</p>","PeriodicalId":46252,"journal":{"name":"Radiological Physics and Technology","volume":" ","pages":"878-887"},"PeriodicalIF":1.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142298279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The effect on gastrointestinal peristalsis for magnetic resonance cholangiopancreatography during breath-holding methods.","authors":"Yuhei Otsuka, Tomoya Nakamura, Nao Kajihara, Takao Tashiro","doi":"10.1007/s12194-024-00846-2","DOIUrl":"10.1007/s12194-024-00846-2","url":null,"abstract":"<p><p>The breath-hold (BH) 3D magnetic resonance cholangiopancreatography method has been reported to suppress \"respiratory artifacts\"; however, the influence of gastrointestinal peristalsis around the target organs has not been discussed. In contrast, the autonomic nervous system has been reported to affect gastrointestinal peristalsis and BH imaging has been reported to influence venous blood flow signal (BFS) through its involvement with the autonomic nervous system. We examined the impact of BH imaging on gastrointestinal peristalsis. Seven healthy volunteers participated. Three respiratory patterns-free breathing (FB), BH at maximum inspiration (Insp-BH), and BH at maximum expiration (Exp-BH)-were used. Gastrointestinal peristalsis was measured using cine MRI. Cine MRI data were analyzed using the normalized interframe difference method, focusing on the duodenum and gastric body. Hemodynamic changes resulting from BH methods were evaluated using 2D phase contrast, targeting the inferior vena cava (IVC). The BFS was examined for all phases of each respiratory pattern. Peristalsis variation in the duodenum showed no significant differences among FB, Exp-BH, and Insp-BH. In the gastric body, no significant differences were observed between FB and Exp-BH or between Exp-BH and Insp-BH. However, a significant difference emerged between FB and Insp-BH. Regarding BFS, in the IVC, significant differences were observed between Exp-BH and Insp-BH and between FB and Insp-BH (both, p < 0.01), with no significant difference between FB and Exp-BH. Insp-BH reduces venous blood flow and suppresses the influence of peristalsis variation.</p>","PeriodicalId":46252,"journal":{"name":"Radiological Physics and Technology","volume":" ","pages":"888-895"},"PeriodicalIF":1.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142356119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}