Radiological Physics and Technology最新文献

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Verification of image quality improvement by deep learning reconstruction to 1.5 T MRI in T2-weighted images of the prostate gland. 在前列腺 T2 加权图像中,验证通过深度学习重构 1.5 T MRI 提高图像质量的效果。
IF 1.7
Radiological Physics and Technology Pub Date : 2024-09-01 Epub Date: 2024-06-08 DOI: 10.1007/s12194-024-00819-5
Yoshiomi Sato, Kiyoshi Ohkuma
{"title":"Verification of image quality improvement by deep learning reconstruction to 1.5 T MRI in T2-weighted images of the prostate gland.","authors":"Yoshiomi Sato, Kiyoshi Ohkuma","doi":"10.1007/s12194-024-00819-5","DOIUrl":"10.1007/s12194-024-00819-5","url":null,"abstract":"<p><p>This study aimed to evaluate whether the image quality of 1.5 T magnetic resonance imaging (MRI) of the prostate is equal to or higher than that of 3 T MRI by applying deep learning reconstruction (DLR). To objectively analyze the images from the 13 healthy volunteers, we measured the signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) of the images obtained by the 1.5 T scanner with and without DLR, as well as for images obtained by the 3 T scanner. In the subjective, T2W images of the prostate were visually evaluated by two board-certified radiologists. The SNRs and CNRs in 1.5 T images with DLR were higher than that in 3 T images. Subjective image scores were better for 1.5 T images with DLR than 3 T images. The use of the DLR technique in 1.5 T MRI substantially improved the SNR and image quality of T2W images of the prostate gland, as compared to 3 T MRI.</p>","PeriodicalId":46252,"journal":{"name":"Radiological Physics and Technology","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141293816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Air inflow into vacuum-type immobilization devices impacts setup errors. 空气流入真空固定装置会影响设置误差。
IF 1.7
Radiological Physics and Technology Pub Date : 2024-09-01 Epub Date: 2024-06-19 DOI: 10.1007/s12194-024-00822-w
Fumiyasu Matsubayashi, Tatsuya Kamima, Yasushi Ito, Yasuo Yoshioka
{"title":"Air inflow into vacuum-type immobilization devices impacts setup errors.","authors":"Fumiyasu Matsubayashi, Tatsuya Kamima, Yasushi Ito, Yasuo Yoshioka","doi":"10.1007/s12194-024-00822-w","DOIUrl":"10.1007/s12194-024-00822-w","url":null,"abstract":"<p><p>We aimed to determine the impact of air inflow into vacuum-type immobilization devices (VIDs) on setup errors. We assigned 70 patients undergoing radiotherapy for head and neck cancer to groups V (n = 34) or N (n = 36) according to whether the VIDs were deflated weekly or not deflated during treatment, respectively. We calculated systematic errors (Σ) as the standard deviations (SDs) of mean errors, and random errors (σ) as the root mean square of SDs in each patient. We compared overall means (μ), SDs (SD<sub>overall</sub>), random errors and systematic errors. We also measured temporary pressure changes in VIDs to determine the influence of pressure changes in VIDs on setup errors. The μ was within 0.20 mm and 0.2° in both groups, whereas SD<sub>overall</sub> significantly differed between them. The SD<sub>overall</sub> differed the most in the Roll axes of groups N (0. 87°) and V (0.58°). The Σ and σ values were lower in all axes of group V than in group N. Despite the initial deflation target of - 70 kPa, the pressure in VIDs reached - 5 kPa at the end of treatment. However, weekly deflation apparently maintained pressure at - 20 kPa. Effective pressure control in VIDs can reduce patient-by-patient variation and improve setup reproducibility for individual patients, consequently resulting in small variations among overall setup errors.</p>","PeriodicalId":46252,"journal":{"name":"Radiological Physics and Technology","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141421354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The relationship between diffusion tensor imaging and the clinical classification of cubital tunnel syndrome. 弥散张量成像与肘管综合征临床分类之间的关系。
IF 1.7
Radiological Physics and Technology Pub Date : 2024-09-01 Epub Date: 2024-05-24 DOI: 10.1007/s12194-024-00813-x
Mitsuhiro Kimura, Shuji Nagata, Makoto Suzuki, Kazutaka Nashiki, Hidemichi Kawata, Toshi Abe
{"title":"The relationship between diffusion tensor imaging and the clinical classification of cubital tunnel syndrome.","authors":"Mitsuhiro Kimura, Shuji Nagata, Makoto Suzuki, Kazutaka Nashiki, Hidemichi Kawata, Toshi Abe","doi":"10.1007/s12194-024-00813-x","DOIUrl":"10.1007/s12194-024-00813-x","url":null,"abstract":"<p><p>The purpose of the study was to investigate the relationship between diffusion tensor imaging (DTI) and the clinical classification of cubital tunnel syndrome (CuTS). Ten patients with CuTS (7 men and 3 women; mean age: 52.7 years) and 5 patients without ulnar neuropathy (2 men and 3 women; mean age: 38.0 years) were enrolled in this retrospective study. Fifteen patients were clinically classified into three groups: \"Normal\", \"1 and 2A\", and \"2B and 3\" by an orthopedic surgeon using the modified McGowan stages. DTI was acquired using a 3.0-T MRI. Fractional anisotropy (FA) of the ulnar nerve was measured in slices covering 20 mm proximal to 20 mm distal to ulnar sulcus. Median FA values in each group were compared by Kruskal-Wallis and Steel-Dwass test (P < 0.05). Five patients with CuTS were classified as \"1 and 2A\" and five patients as \"2B and 3\". The FA values, proximal 12 mm to the ulnar sulcus were 0.486 ± 0.117, 0.425 ± 0.166 and 0.298 ± 0.0386 in the \"Normal\", \"1 and 2A\" and \"2B and 3\" groups, respectively. The FA values of patients classified as \"Normal\" were significantly higher than those classified as \"2B and 3\" (P = 0.0326 in Steel-Dwass test). FA proximal to the ulnar sulcus might be associated to the modified McGowan stages for the clinical classification of CuTS.</p>","PeriodicalId":46252,"journal":{"name":"Radiological Physics and Technology","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141088448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Identification of peroneal artery perforators using non-contrast-enhanced T2prep multi-shot gradient echo planar imaging MRA. 利用非对比度增强 T2prep 多拍梯度回波平面成像 MRA 鉴定腓动脉穿孔器。
IF 1.7
Radiological Physics and Technology Pub Date : 2024-09-01 Epub Date: 2024-05-28 DOI: 10.1007/s12194-024-00799-6
Yutaka Shigenaga, Takeo Osaki, Nobuyuki Murai, Saki Kamino, Koji Nakao, Ryohei Kawasaki, Daisuke Takenaka, Takayuki Ishida
{"title":"Identification of peroneal artery perforators using non-contrast-enhanced T2prep multi-shot gradient echo planar imaging MRA.","authors":"Yutaka Shigenaga, Takeo Osaki, Nobuyuki Murai, Saki Kamino, Koji Nakao, Ryohei Kawasaki, Daisuke Takenaka, Takayuki Ishida","doi":"10.1007/s12194-024-00799-6","DOIUrl":"10.1007/s12194-024-00799-6","url":null,"abstract":"<p><p>The purpose of this study was to investigate the spatial resolution of non-contrast-enhanced (CE) T2prep multi-shot gradient echo planar imaging (MSG-EPI) magnetic resonance angiography (MRA) required to identify peroneal artery perforators and demonstrate its effectiveness in preoperative simulation. Twenty-six legs of 13 volunteers were scanned using non-CE T2prep MSG-EPI-MRA at three spatial resolutions: 1.0-, 0.8-, and 0.6-mm isotropic voxels. The location and number of peroneal artery perforators that could be candidates for free fibula flaps were identified by consensus among three plastic surgeons. Surgeons distinguished between septocutaneous and musculocutaneous perforators using MRA, and confirmed the accuracy of their presence and identification using ultrasonography (US). The ability to detect hypoplasia or stenosis of the anterior tibial, posterior tibial, and peroneal arteries was evaluated by confirming the consistency between the MRA and US results. The number of cutaneous perforators identified using MRA and confirmed using US was 39, 51, and 52 at each respective resolution. The discrimination accuracies between septocutaneous and musculocutaneous perforators were 92.3%, 96.1%, and 96.2%. The number of identified septocutaneous perforators was 1.3 ± 0.6, 1.6 ± 0.8, and 1.7 ± 0.8 at 1.0-, 0.8-, and 0.6-mm data, respectively. All the MRA results, including hypoplasia and stenosis, were consistent with the US results. Non-CE T2prep MSG-EPI-MRA with a spatial resolution of 0.8 mm or less shows promise for identifying septocutaneous perforators of the peroneal artery, suggesting its potential as an alternative to conventional imaging methods for the preoperative planning of free fibula osteocutaneous flap transfers.</p>","PeriodicalId":46252,"journal":{"name":"Radiological Physics and Technology","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141157741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adjustment of scan delay for bolus tracking with cardiothoracic ratio of CT scout image for hepatic artery phase of hepatic dynamic CT. 在肝脏动态 CT 的肝动脉阶段,利用 CT 扫描图像的心胸比率调整栓子追踪的扫描延迟。
IF 1.7
Radiological Physics and Technology Pub Date : 2024-09-01 Epub Date: 2024-05-17 DOI: 10.1007/s12194-024-00814-w
Koji Muroga, Kanta Kitahara
{"title":"Adjustment of scan delay for bolus tracking with cardiothoracic ratio of CT scout image for hepatic artery phase of hepatic dynamic CT.","authors":"Koji Muroga, Kanta Kitahara","doi":"10.1007/s12194-024-00814-w","DOIUrl":"10.1007/s12194-024-00814-w","url":null,"abstract":"<p><p>This study aimed to determine the scan delay for bolus tracking in the hepatic artery phase (HAP) of hepatic dynamic computed tomography (CT) using the cardiothoracic ratio (CTR) from CT scout images. We retrospectively studied 188 patients who underwent hepatic dynamic CT, 24 of whom had scan delays adjusted for CTR. The contrast enhancement of the abdominal aorta, portal vein, hepatic vein, and hepatic parenchyma was calculated for HAP. The adequacy of the scan timing for HAP was assessed using three classifications: early, appropriate, or late. The effect of HAP on scan timing adequacy was determined using multivariate logistic regression analysis, and the optimal cutoff value of CTR was evaluated using receiver operating characteristic analysis. The trigger times for bolus tracking (odds ratio: 1.58) and CTR (odds ratio: 1.23) were significantly affected by the appropriate scan timing of the HAP. The optimal cutoff value of CTR was 59.3%. The scan timing of HAP with a scan delay of 15 s was 14% of early and 86% of appropriate, and the proportion of early in CTR ≥ 60% (early, 52%; appropriate, 48%) was higher than that in CTR < 60% (early, 6%; appropriate, 94%). Adjusting the scan delay to 20 s in CTR ≥ 60% increased the proportion of appropriate (early, 4%; appropriate, 96%). The CTR of a CT scout image is an effective index for determining the scan delay for bolus tracking. Adjusting the scan delay by CTR can provide appropriate HAP images in more patients. Trial registration number: R-080; date of registration: 9 March 2023, retrospectively registered.</p>","PeriodicalId":46252,"journal":{"name":"Radiological Physics and Technology","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140959785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Data analysis of average glandular dose in mammography toward revision of the diagnostic reference level of Japan. 乳腺 X 射线照相术中平均腺体剂量的数据分析,以修订日本的诊断参考水平。
IF 1.7
Radiological Physics and Technology Pub Date : 2024-09-01 Epub Date: 2024-06-21 DOI: 10.1007/s12194-024-00823-9
Toru Negishi, Yusuke Koba, Kiyomitsu Shinsho, Daisuke Fujise, Masahiro Sai, Hiroko Nishide
{"title":"Data analysis of average glandular dose in mammography toward revision of the diagnostic reference level of Japan.","authors":"Toru Negishi, Yusuke Koba, Kiyomitsu Shinsho, Daisuke Fujise, Masahiro Sai, Hiroko Nishide","doi":"10.1007/s12194-024-00823-9","DOIUrl":"10.1007/s12194-024-00823-9","url":null,"abstract":"<p><p>Diagnostic reference level (DRL) for mammography for 2015 and 2020 has been published by J-RIME. More new dose studies are needed to revise the next DRL. In preparation for the next revision of the DRL for mammography, this study investigated data from the Japan Central Organization on Quality Assurance of Breast Cancer Screening on the mean average glandular dose (AGD) for institutional image accreditation in 2019-2023 and the relationship between the average at eligible institutions to date and the type of breast X-ray system. The 95th percentile values of the AGD distributions for the Computed Radiography (CR) and Flat Panel Detector (FPD) systems were 2.5 mGy and 2.0 mGy, respectively. Moreover, it is assumed that AGD is decreasing due to the spread of FPD systems, and it is expected that the further spread of FPD systems and systems with W/Rh target/filter will reduce AGD in future.</p>","PeriodicalId":46252,"journal":{"name":"Radiological Physics and Technology","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141433052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigation of distributed learning for automated lesion detection in head MR images. 研究分布式学习在头部磁共振图像中的自动病灶检测。
IF 1.7
Radiological Physics and Technology Pub Date : 2024-09-01 Epub Date: 2024-07-24 DOI: 10.1007/s12194-024-00827-5
Aiki Yamada, Shouhei Hanaoka, Tomomi Takenaga, Soichiro Miki, Takeharu Yoshikawa, Yukihiro Nomura
{"title":"Investigation of distributed learning for automated lesion detection in head MR images.","authors":"Aiki Yamada, Shouhei Hanaoka, Tomomi Takenaga, Soichiro Miki, Takeharu Yoshikawa, Yukihiro Nomura","doi":"10.1007/s12194-024-00827-5","DOIUrl":"10.1007/s12194-024-00827-5","url":null,"abstract":"<p><p>In this study, we investigated the application of distributed learning, including federated learning and cyclical weight transfer, in the development of computer-aided detection (CADe) software for (1) cerebral aneurysm detection in magnetic resonance (MR) angiography images and (2) brain metastasis detection in brain contrast-enhanced MR images. We used datasets collected from various institutions, scanner vendors, and magnetic field strengths for each target CADe software. We compared the performance of multiple strategies, including a centralized strategy, in which software development is conducted at a development institution after collecting de-identified data from multiple institutions. Our results showed that the performance of CADe software trained through distributed learning was equal to or better than that trained through the centralized strategy. However, the distributed learning strategies that achieved the highest performance depend on the target CADe software. Hence, distributed learning can become one of the strategies for CADe software development using data collected from multiple institutions.</p>","PeriodicalId":46252,"journal":{"name":"Radiological Physics and Technology","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11341643/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141761605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical application of single-shot fast spin-echo sequence for cerebrospinal fluid flow MR imaging. 脑脊液流磁共振成像中单次快速自旋回波序列的临床应用。
IF 1.7
Radiological Physics and Technology Pub Date : 2024-09-01 Epub Date: 2024-07-19 DOI: 10.1007/s12194-024-00825-7
Takahito Bessho, Tatsuya Hayashi, Shuhei Shibukawa, Kazuyuki Kourin, Takashi Shouda
{"title":"Clinical application of single-shot fast spin-echo sequence for cerebrospinal fluid flow MR imaging.","authors":"Takahito Bessho, Tatsuya Hayashi, Shuhei Shibukawa, Kazuyuki Kourin, Takashi Shouda","doi":"10.1007/s12194-024-00825-7","DOIUrl":"10.1007/s12194-024-00825-7","url":null,"abstract":"<p><p>In normal-pressure hydrocephalus, disturbances in cerebrospinal fluid (CSF) circulation occur; therefore, understanding CSF dynamics is crucial. The two-dimensional phase-contrast (2D-PC) method, a common approach for visualizing CSF flow on MRI, often presents challenges owing to prominent vein signals and excessively high contrast, hindering the interpretation of morphological information. Therefore, we devised a new imaging method that utilizes T<sub>2</sub>-weighted high-signal intensification of the CSF and saturation pulses, without requiring specialized imaging sequences. This sequence utilized a T<sub>2</sub>-weighted single-shot fast spin-echo combined with multi-phase imaging synchronized with a pulse wave. Optimal imaging conditions (repetition time, presence/absence of fast recovery, and echo time) were determined using self-made contrast and single-plate phantoms to evaluate signal-to-noise ratio, contrast ratio, and spatial resolution. In certain clinical cases of hydrocephalus, confirming CSF flow using 2D-PC was challenging. However, our method enabled the visualization of CSF flow, proving to be useful in understanding the pathophysiology of hydrocephalus.</p>","PeriodicalId":46252,"journal":{"name":"Radiological Physics and Technology","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141724711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of monthly variations in electrometer calibration coefficients using a charge generator for radiation therapy. 使用用于放射治疗的电荷发生器评估电量计校准系数的月度变化。
IF 1.7
Radiological Physics and Technology Pub Date : 2024-09-01 Epub Date: 2024-08-01 DOI: 10.1007/s12194-024-00830-w
Motohiro Kawashima, Maria Varnava, Shuichi Ozawa, Hiromitsu Higuchi, Yoshihiko Hoshino, Mutsumi Tashiro
{"title":"Evaluation of monthly variations in electrometer calibration coefficients using a charge generator for radiation therapy.","authors":"Motohiro Kawashima, Maria Varnava, Shuichi Ozawa, Hiromitsu Higuchi, Yoshihiko Hoshino, Mutsumi Tashiro","doi":"10.1007/s12194-024-00830-w","DOIUrl":"10.1007/s12194-024-00830-w","url":null,"abstract":"<p><p>Electrometers are important devices that are part of the standard dosimetry system. Therefore, we evaluated the variation of electrometer calibration coefficients (k<sub>elec</sub>) over 1 year in this study. We investigated two types of electrometers: a rate mode and an integrate mode. Each electrometer was connected to a charge generator, a constant charge was applied, and k<sub>elec</sub> was determined by measuring the current. The current measurements were repeated once a month. For electrometers with multiple ranges, measurements were taken at low and medium ranges. Almost all k<sub>elec</sub> measurements agreed within 0.2% of the initial measurements. However, the low range of the electrometer with an integrate mode showed seasonal variation, with a variation greater than 0.2%. This study shows that electrometers may exhibit errors that cannot be detected through annual inspections. The importance of quality assurance using a charge generator at one's own institution was demonstrated.</p>","PeriodicalId":46252,"journal":{"name":"Radiological Physics and Technology","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11341583/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141876265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Influence of Gd-EOB-DTPA on proton-density fat fraction in the liver using chemical shift-encoded magnetic resonance imaging at 3-T. 利用 3 T 化学位移编码磁共振成像技术研究 Gd-EOB-DTPA 对肝脏质子密度脂肪分数的影响。
IF 1.7
Radiological Physics and Technology Pub Date : 2024-09-01 Epub Date: 2024-05-10 DOI: 10.1007/s12194-024-00811-z
Makoto Suzuki, Tatsuya Hayashi, Kazutaka Nashiki, Hidemichi Kawata, Shuji Nagata, Toshi Abe
{"title":"Influence of Gd-EOB-DTPA on proton-density fat fraction in the liver using chemical shift-encoded magnetic resonance imaging at 3-T.","authors":"Makoto Suzuki, Tatsuya Hayashi, Kazutaka Nashiki, Hidemichi Kawata, Shuji Nagata, Toshi Abe","doi":"10.1007/s12194-024-00811-z","DOIUrl":"10.1007/s12194-024-00811-z","url":null,"abstract":"<p><p>Non-alcoholic fatty liver disease (NAFLD) and its advanced stage, non-alcoholic steatohepatitis (NASH), have become increasingly prevalent owing to the rise in metabolic syndromes. Accurate assessment of hepatic fat deposition and inflammation is crucial for diagnosing and managing NAFLD/NASH. We investigated the influence of Gd-EOB-DTPA, (EOB) on proton-density fat fraction (PDFF) measurements using chemical shift-encoded magnetic resonance imaging (CSE-MRI) at 3-T. In total, 431 patients who underwent EOB contrast-enhanced MRI were included. PDFF measurements were obtained from pre- and post-contrast CSE-MRI. Linear regression and Bland-Altman analyses were performed to assess the correlation and agreement between pre- and post-EOB PDFF measurements. Relative enhancement (RE) of the liver was calculated as an EOB uptake index. There was a significant decrease in PDFF following EOB administration compared with the pre-contrast values (P < 0.0001), which was observed across all PDFF ranges (< 10% and ≥ 10%). Linear regression analysis revealed high correlation between pre- and post-EOB PDFF measurements. Bland-Altman analysis indicated a small bias between pre- and post-EOB PDFF values. Subgroup analysis based on RE showed a significant difference in ΔPDFF between patients with high RE (> 120%) and those with lower RE levels. EOB administration resulted in a slight decrease in PDFF measurements obtained using CSE-MRI at 3-T. We were able to generalize and clarify that the PDFF of the liver on 3D CSE-MRI at 3-T was slightly decreased after EOB administration as we used a larger group of patients compared to previous studies.</p>","PeriodicalId":46252,"journal":{"name":"Radiological Physics and Technology","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140904933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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