Respirology Case Reports最新文献_第6页

Shrinking Lung Syndrome in Adolescent Systemic Lupus Erythematosus: Diagnostic Utility of Diaphragmatic Ultrasound. 青少年系统性红斑狼疮肺萎缩综合征：横膈膜超声的诊断价值。

IF 0.7

Respirology Case Reports Pub Date : 2026-08-26 eCollection Date: 2026-08-01 DOI: 10.1002/rcr2.70733

Ayesha Farid, Abdul Basit, Ali Raza Rana, Sharaz Ahmed, Majeed Haq

{"title":"Shrinking Lung Syndrome in Adolescent Systemic Lupus Erythematosus: Diagnostic Utility of Diaphragmatic Ultrasound.","authors":"Ayesha Farid, Abdul Basit, Ali Raza Rana, Sharaz Ahmed, Majeed Haq","doi":"10.1002/rcr2.70733","DOIUrl":"10.1002/rcr2.70733","url":null,"abstract":"Shrinking lung syndrome (SLS) is a rare pulmonary complication of systemic lupus erythematosus (SLE), characterized by dyspnoea, reduced lung volumes, and elevated diaphragms without significant parenchymal lung disease. We report a 17-year-old female with SLE presenting with progressive dyspnoea, dry cough, and pleuritic chest pain. Pulmonary function tests showed a restrictive defect (forced vital capacity 39% predicted) with preserved diffusing capacity. High-resolution computed tomography demonstrated reduced lung volumes with bilateral diaphragmatic elevation and basal atelectasis, without interstitial lung disease. Diaphragmatic ultrasound revealed reduced excursion and decreased thickening fraction, indicating diaphragmatic dysfunction. Alternative cardiopulmonary and neuromuscular causes were excluded, establishing the diagnosis of SLS. The patient was treated with corticosteroids and theophylline, resulting in symptomatic improvement. This case highlights the importance of recognizing SLS and demonstrates the diagnostic value of diaphragmatic ultrasound as a non-invasive tool facilitating early diagnosis and management.","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"14 8","pages":"e70733"},"PeriodicalIF":0.7,"publicationDate":"2026-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13508146/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148832985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pulmonary Infiltrates, Airway Mucosal Lesions and Respiratory Microbiology After Freshwater Drowning: A Case Report. 淡水溺水后肺浸润、气道黏膜病变和呼吸道微生物学1例报告。

IF 0.7

Respirology Case Reports Pub Date : 2026-08-26 eCollection Date: 2026-08-01 DOI: 10.1002/rcr2.70731

Huan Xiao, Yu-Xi Rao, Mei-Li Xu, Wei Wang, Chao-Qian Li

{"title":"Pulmonary Infiltrates, Airway Mucosal Lesions and Respiratory Microbiology After Freshwater Drowning: A Case Report.","authors":"Huan Xiao, Yu-Xi Rao, Mei-Li Xu, Wei Wang, Chao-Qian Li","doi":"10.1002/rcr2.70731","DOIUrl":"10.1002/rcr2.70731","url":null,"abstract":"Early pulmonary abnormalities after freshwater drowning can be overinterpreted as bacterial pneumonia, especially when inflammatory biomarkers and respiratory microbiology are positive. A 20-year-old man was resuscitated after approximately 2 min of freshwater submersion. Day 1 chest CT showed bilateral lower-lobe-predominant opacities compatible with non-cardiogenic pulmonary oedema and aspiration-related lung injury, with near-complete resolution by Day 25. Day 3 bronchoscopy showed diffuse, non-removable, millet-seed-like whitish tracheal mucosal protrusions with hyperaemia and oedema, compatible with acute irritative airway injury. BALF mNGS detected multiple gram-negative bacterial signals, predominantly Klebsiella pneumoniae, while sputum culture yielded ESBL-negative, susceptible K. pneumoniae. Possible drowning-associated pneumonia was considered because of aspiration, fever, markedly elevated inflammatory biomarkers and concordant microbiology; however, rapid radiological improvement and clinical stability suggested a substantial non-infectious component. The patient recovered after an 8-day course of piperacillin-tazobactam without antibiotic escalation, corticosteroids, mechanical ventilation or acute respiratory distress syndrome.","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"14 8","pages":"e70731"},"PeriodicalIF":0.7,"publicationDate":"2026-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13508129/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148832868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Probable Tigecycline-Induced Acute Eosinophilic Pneumonia: A Case Report. 可能的替加环素引起的急性嗜酸性肺炎1例报告。

IF 0.7

Respirology Case Reports Pub Date : 2026-08-25 eCollection Date: 2026-08-01 DOI: 10.1002/rcr2.70726

Annette Eom, Mutsumi Kioka

{"title":"Probable Tigecycline-Induced Acute Eosinophilic Pneumonia: A Case Report.","authors":"Annette Eom, Mutsumi Kioka","doi":"10.1002/rcr2.70726","DOIUrl":"10.1002/rcr2.70726","url":null,"abstract":"A 25-year-old man developed acute hypoxaemic respiratory failure after 21 days of tigecycline therapy for osteomyelitis caused by multidrug-resistant organisms. Chest computed tomography demonstrated bilateral consolidations, ground-glass opacities, interlobular septal thickening, small bilateral pleural effusions and mediastinal lymphadenopathy. Bronchoalveolar lavage (BAL) revealed marked eosinophilia (99%-100%) despite minimal peripheral eosinophilia. Alternative causes, including infectious, parasitic, autoimmune and other potential aetiologies, were carefully evaluated. Based on the temporal relationship with tigecycline exposure, marked BAL eosinophilia, exclusion of alternative causes and the overall clinical presentation, probable tigecycline-induced acute eosinophilic pneumonia (AEP) was diagnosed. Tigecycline was discontinued, cefiderocol was initiated for concomitant multidrug-resistant Acinetobacter baumannii, and systemic corticosteroid therapy was administered, followed by progressive clinical and radiographic improvement. Although the clinical response followed multiple simultaneous interventions and therefore does not establish causality, the overall findings support tigecycline as the probable causative agent. To our knowledge, this is the first reported case of probable tigecycline-associated AEP. This case highlights the importance of considering AEP in patients who develop unexplained respiratory deterioration during tigecycline therapy and underscores the diagnostic value of BAL, particularly in the absence of marked peripheral eosinophilia.","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"14 8","pages":"e70726"},"PeriodicalIF":0.7,"publicationDate":"2026-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13505188/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148819911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recurrent Spasmodic Croup-Like Episodes With Cough-Predominant Symptoms in an Atopic School-Aged Child: The Importance of Integrated Upper- and Lower-Airway Management. 特应性学龄儿童以咳嗽为主要症状的反复发作痉挛性群样发作：综合上下气道管理的重要性。

IF 0.7

Respirology Case Reports Pub Date : 2026-08-25 eCollection Date: 2026-08-01 DOI: 10.1002/rcr2.70686

Rina Sakaguchi, Shizuka Mitsubuchi, Yusuke Miyashita, Toshihiko Nonaka, Kimitoshi Nakamura

{"title":"Recurrent Spasmodic Croup-Like Episodes With Cough-Predominant Symptoms in an Atopic School-Aged Child: The Importance of Integrated Upper- and Lower-Airway Management.","authors":"Rina Sakaguchi, Shizuka Mitsubuchi, Yusuke Miyashita, Toshihiko Nonaka, Kimitoshi Nakamura","doi":"10.1002/rcr2.70686","DOIUrl":"10.1002/rcr2.70686","url":null,"abstract":"Recurrent spasmodic croup is uncommon in school-aged children and may reflect an atopy-associated upper-airway dysfunction rather than a viral illness. We reported a 14-year-old boy with perennial allergic rhinitis and cough-predominant asthma who experienced 10 early-morning episodes of barking cough and inspiratory stridor between 2020 and 2024. Despite the long-term prescription of inhaled corticosteroid therapy, seasonal discontinuation and inconsistent adherence were evident, and recurrent episodes persisted. After referral, integrated management including stepwise allergic-rhinitis treatment and re-education promoting year-round adherence was implemented. Although the direct impact of these interventions on episode recurrence could not be determined, cough symptoms improved and asthma control stabilized despite persistently elevated fractional nitric oxide (~60 ppb). Integrated upper- and lower-airway management and adherence optimization may help stabilize cough-predominant symptoms in atopic children.","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"14 8","pages":"e70686"},"PeriodicalIF":0.7,"publicationDate":"2026-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13504217/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148819936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pulmonary Sarcoidosis Mimicking Eosinophilic Bronchiolitis Diagnosed by Cutibacterium Acnes Positivity. 模拟嗜酸性细支气管炎的肺结节病由痤疮表皮杆菌阳性诊断。

IF 0.7

Respirology Case Reports Pub Date : 2026-08-25 eCollection Date: 2026-08-01 DOI: 10.1002/rcr2.70736

Keishi Sugino, Hirotaka Ono, Mikako Saito, Miho Kobayashi, Seiji Igarashi

引用次数: 0

Spurious Fingertip Oxygen Desaturation During the 6-Minute Walk Test in a Patient With NSIP and Raynaud Phenomenon: The Value of Forehead Pulse Oximetry and Transcutaneous Oxygen Tension. NSIP患者6分钟步行试验中假指尖氧饱和度和雷诺现象：前额脉搏血氧仪和经皮氧张力的价值。

IF 0.7

Respirology Case Reports Pub Date : 2026-08-25 eCollection Date: 2026-08-01 DOI: 10.1002/rcr2.70737

Yusuke Nakamura, Masayoshi Takamori, Honoka Sunaga, Kosuke Natsume, Yuri Nomura, Yuto Goto, Nobuhiko Tsukada, Azusa Tsukada, Nobuhiko Uchida, Nana Yazawa, Hiromi Hoshi, Yasuo Shimizu, Seiji Niho

{"title":"Spurious Fingertip Oxygen Desaturation During the 6-Minute Walk Test in a Patient With NSIP and Raynaud Phenomenon: The Value of Forehead Pulse Oximetry and Transcutaneous Oxygen Tension.","authors":"Yusuke Nakamura, Masayoshi Takamori, Honoka Sunaga, Kosuke Natsume, Yuri Nomura, Yuto Goto, Nobuhiko Tsukada, Azusa Tsukada, Nobuhiko Uchida, Nana Yazawa, Hiromi Hoshi, Yasuo Shimizu, Seiji Niho","doi":"10.1002/rcr2.70737","DOIUrl":"10.1002/rcr2.70737","url":null,"abstract":"Reduced digital perfusion associated with Raynaud phenomenon may cause spuriously low fingertip pulse oximetry readings during the 6-minute walk test (6MWT), potentially leading to overestimation of exercise-induced hypoxaemia in patients with interstitial lung disease. We report a 39-year-old woman with non-specific interstitial pneumonia and Raynaud phenomenon who underwent repeated 6MWTs. Fingertip SpO2 progressively decreased from 96% to 82%, whereas forehead SpO2 remained stable (93%-98%). Simultaneously, transcutaneous oxygen tension (TcPO2) measured on the volar forearm remained unchanged. Progressive finger cooling and digital pallor were also observed. Fingertip SpO2 rapidly returned to baseline during recovery. These findings suggested that the apparent desaturation reflected reduced digital perfusion rather than true systemic hypoxaemia. This case highlights the potential limitations of fingertip pulse oximetry during exercise in patients with Raynaud phenomenon. Alternative methods of assessing oxygenation, such as forehead pulse oximetry or TcPO2, may be useful during the 6MWT when fingertip SpO2 readings are discordant with the clinical presentation.","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"14 8","pages":"e70737"},"PeriodicalIF":0.7,"publicationDate":"2026-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13504363/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148820006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Mimic of Metastatic Malignancy: Dietary Supplement-Associated Drug-Induced Lung Injury Presenting as Multiple Pulmonary Nodules With an Acute Fibrinous and Organizing Pneumonia Pattern. 一种模拟转移性恶性肿瘤：膳食补充剂相关药物引起的肺损伤表现为多发性肺结节，伴急性纤维性和组织性肺炎。

IF 0.7

Respirology Case Reports Pub Date : 2026-08-24 eCollection Date: 2026-08-01 DOI: 10.1002/rcr2.70735

Yuto Goto, Yusuke Nakamura, Nana Yazawa, Kosuke Natsume, Nobuhiko Tsukada, Azusa Tsukada, Nobuaki Yoshida, Yuri Nomura, Akihiro Kawabe, Hiroaki Arakawa, Akihiro Takemasa, Kazuyuki Ishida, Yasuo Shimizu, Seiji Niho

{"title":"A Mimic of Metastatic Malignancy: Dietary Supplement-Associated Drug-Induced Lung Injury Presenting as Multiple Pulmonary Nodules With an Acute Fibrinous and Organizing Pneumonia Pattern.","authors":"Yuto Goto, Yusuke Nakamura, Nana Yazawa, Kosuke Natsume, Nobuhiko Tsukada, Azusa Tsukada, Nobuaki Yoshida, Yuri Nomura, Akihiro Kawabe, Hiroaki Arakawa, Akihiro Takemasa, Kazuyuki Ishida, Yasuo Shimizu, Seiji Niho","doi":"10.1002/rcr2.70735","DOIUrl":"10.1002/rcr2.70735","url":null,"abstract":"Drug-induced lung injury (DILI) may present with diverse radiological and histopathological manifestations. We report a case of dietary supplement-associated DILI presenting as multiple randomly distributed pulmonary nodules mimicking metastatic malignancy and histopathologically exhibiting an acute fibrinous and organizing pneumonia (AFOP) pattern. A 62-year-old man who had taken a dietary supplement containing fermented grain extract, malt extract, and coenzyme Q10 for approximately 15 years developed multiple pulmonary nodules accompanied by marked peripheral eosinophilia. Computed tomography initially raised suspicion of metastatic malignancy. Bronchoalveolar lavage demonstrated eosinophilia, and transbronchial lung cryobiopsy revealed an AFOP pattern with prominent eosinophilic inflammation. The diagnosis of dietary supplement-associated DILI was established based on the exposure history, exclusion of alternative diagnoses, and spontaneous regression of the pulmonary nodules and improvement in eosinophilia following discontinuation of the dietary supplement. This case highlights that dietary supplement-associated DILI may mimic metastatic malignancy by presenting as multiple pulmonary nodules, while histopathological evaluation may reveal an AFOP pattern with marked eosinophilic inflammation.","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"14 8","pages":"e70735"},"PeriodicalIF":0.7,"publicationDate":"2026-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13504219/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148819953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Five Cases of Primary Pulmonary Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma With Atypical Image Findings and Literature Review: A Case Series. 原发性肺粘膜相关淋巴组织（MALT）淋巴瘤5例影像学表现不典型并文献复习。

IF 0.7

Respirology Case Reports Pub Date : 2026-08-21 eCollection Date: 2026-08-01 DOI: 10.1002/rcr2.70727

Yihao Guo, Jinsong Li

引用次数: 0

Chylothorax Following Endoscopic Ultrasound-Guided Fine-Needle Aspiration: A Rare Complication and Its Anatomical Risk Factors. 超声内镜引导下细针穿刺后乳糜胸：一种罕见的并发症及其解剖学危险因素。

IF 0.7

Respirology Case Reports Pub Date : 2026-08-19 eCollection Date: 2026-08-01 DOI: 10.1002/rcr2.70732

Saima Bandarkar, Ahmed Abdelsamad, Yousef Aleid, Ahmed Nasr, Talal AlSaeed, Essa AlGunaim, Derar AlShehab, Adel Ayed, Mohammed I Ghanbar, Sulaiman Khadadah

引用次数: 0

Inhaled N-Acetylcysteine as a Potential Adjunctive Therapy in Mucus Plug-Forming Asthma With Irpex lacteus Isolation: A Case Report. 吸入n -乙酰半胱氨酸作为一种潜在的辅助治疗黏液塞形成哮喘与Irpex乳酸分离：1例报告。

IF 0.7

Respirology Case Reports Pub Date : 2026-08-18 eCollection Date: 2026-08-01 DOI: 10.1002/rcr2.70723

Yuka Uchida, Yusuke Hirao, Koji Kurokawa, Yukari Ichikawa, Shiho Furusho, Haruhiko Ogawa

{"title":"Inhaled N-Acetylcysteine as a Potential Adjunctive Therapy in Mucus Plug-Forming Asthma With Irpex lacteus Isolation: A Case Report.","authors":"Yuka Uchida, Yusuke Hirao, Koji Kurokawa, Yukari Ichikawa, Shiho Furusho, Haruhiko Ogawa","doi":"10.1002/rcr2.70723","DOIUrl":"10.1002/rcr2.70723","url":null,"abstract":"A 68-year-old woman was hospitalized for hypoxemia during an asthma exacerbation with cough, highly tenacious sputum and exertional dyspnoea. Chest computed tomography revealed lower lobe-dominant mucus plugs. Irpex lacteus was identified from both sputum culture and environmental sampling from the patient's bedroom, although diagnostic criteria for allergic bronchopulmonary mycosis were not fulfilled. Wheezing improved after standard therapy; however highly tenacious sputum persisted. Following administration of inhaled N-acetylcysteine (NAC), sputum tenacity improved, followed by improvements in respiratory symptoms, pulmonary function test values and flow-volume curves and the resolution of mucus plugs. This case suggests that highly tenacious sputum may represent a treatable trait in mucus plug-forming asthma and that inhaled NAC may serve as a useful adjunctive therapy in selected patients. Further accumulation of cases is needed to clarify the clinical significance of Irpex lacteus colonisation.","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"14 8","pages":"e70723"},"PeriodicalIF":0.7,"publicationDate":"2026-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13483092/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148799346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0