Respirology Case ReportsPub Date : 2025-08-19eCollection Date: 2025-08-01DOI: 10.1002/rcr2.70318
{"title":"Correction to \"A Case of Stevens-Johnson Syndrome Triggered by Methicillin-Resistant <i>Staphylococcus aureus</i> Infection During Pembrolizumab Treatment for Lung Squamous Cell Carcinoma\".","authors":"","doi":"10.1002/rcr2.70318","DOIUrl":"10.1002/rcr2.70318","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1002/rcr2.70290.].</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 8","pages":"e70318"},"PeriodicalIF":0.8,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12364610/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Case of Hybrid of Congenital Pulmonary Airway Malformation and Anomalous Systemic Blood Supply Presenting Elevated Serum Levels of Carbohydrate Antigen 19-9.","authors":"Yukihisa Inoue, Osamu Matsubara, Tetsu Hara, Hiroyuki Shimada, Kazuki Yamanaka, Yasuto Jinn","doi":"10.1002/rcr2.70323","DOIUrl":"10.1002/rcr2.70323","url":null,"abstract":"<p><p>Congenital pulmonary airway malformations (CPAM) are rare congenital pulmonary anomalies in adults and are at risk of malignant transformation. CPAM lesions with abnormal systemic blood supply are considered hybrid lesions (HL). There are few cases of HL in adults. Here, we report a 44-year-old woman who presented with elevated serum carbohydrate antigen19-9 (CA19-9) levels and was diagnosed with HL with abnormal arterial blood flow from the celiac artery. After surgical resection, serum CA19-9 levels immediately decreased to the normal range. Immunohistochemical staining of the resected lung tissue showed positive staining for CA19-9 in the bronchiolar ciliated columnar epithelial cells. This report highlights that elevated serum CA19-9 levels may be seen in HL, even in the absence of malignancy.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 8","pages":"e70323"},"PeriodicalIF":0.8,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12364611/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Tracheobronchial Tuberculosis During Treatment for Bronchial Asthma.","authors":"Hiromitsu Sakai, Hirokazu Tokuyasu, Shuichi Matsuoka, Katsunori Arai, Chika Esumi, Akira Yamasaki","doi":"10.1002/rcr2.70314","DOIUrl":"10.1002/rcr2.70314","url":null,"abstract":"<p><p>Tracheobronchial tuberculosis is a disease that requires careful attention when treating patients with chronic cough, such as those with bronchial asthma.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 8","pages":"e70314"},"PeriodicalIF":0.8,"publicationDate":"2025-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12358676/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144884096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Early Pseudoprogression After Tarlatamab in Small-Cell Lung Cancer: A Case Report.","authors":"Yoshio Nakano, Hiroka Serizawa, Yuri Enomoto, Yusuke Kuze, Norio Okamoto, Iwao Gohma","doi":"10.1002/rcr2.70319","DOIUrl":"10.1002/rcr2.70319","url":null,"abstract":"<p><p>Pseudoprogression, a transient radiographic flare caused by immune infiltration, is common after immune-checkpoint inhibitors but has not been reported with tarlatamab, a bispecific T-cell engager approved for third-line small-cell lung cancer (SCLC). A 57-year-old woman with extensive-stage SCLC and syndrome of inappropriate antidiuretic hormone secretion (SIADH) received tarlatamab. Within hours, she developed bone pain; Day 7 imaging showed marked tumour swelling and pleural effusion despite negative cytology and rising serum sodium. Therapy continued. By Day 13, computed tomography demonstrated regression of thoracic and hepatic lesions and falling pro-gastrin-releasing peptide (pro-GRP). Early pseudoprogression and paraneoplastic biomarker improvement may predict efficacy.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 8","pages":"e70319"},"PeriodicalIF":0.8,"publicationDate":"2025-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12358216/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144875844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Respirology Case ReportsPub Date : 2025-08-17eCollection Date: 2025-08-01DOI: 10.1002/rcr2.70321
Bader J Alghamdi, Maha A Safhi, Reuof M Almakati
{"title":"Post-Engraftment Syndrome Following Autologous Haematopoietic Stem Cell Transplantation in a Patient With Relapsed Hodgkin Lymphoma.","authors":"Bader J Alghamdi, Maha A Safhi, Reuof M Almakati","doi":"10.1002/rcr2.70321","DOIUrl":"10.1002/rcr2.70321","url":null,"abstract":"<p><p>Post-engraftment syndrome (PES) is a significant and potentially life-threatening complication of autologous haematopoietic stem cell transplantation (AHSCT) that presents with fever, skin rash and pulmonary involvement. Despite its clinical relevance, PES remains a diagnostic challenge and is often misidentified as an infectious process, leading to a delay in the appropriate treatment. We report the case of a 38-year-old man with relapsed Hodgkin's lymphoma and glucose-6-phosphate dehydrogenase (G6PD) deficiency who developed severe PES following AHSCT. The patient experienced severe respiratory distress and an altered mental status, necessitating intubation and intensive care unit admission. Despite broad-spectrum antimicrobial coverage, his condition deteriorated until intravenous corticosteroids were administered, with a subsequent remarkable clinical response. This case highlights the importance of the early recognition and appropriate management of PES.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 8","pages":"e70321"},"PeriodicalIF":0.8,"publicationDate":"2025-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12358217/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144875846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Respirology Case ReportsPub Date : 2025-08-15eCollection Date: 2025-08-01DOI: 10.1002/rcr2.70317
{"title":"Correction to \"Paraneoplastic Hypoglycaemia in a Patient With Solitary Fibrous Tumor of Pleura\".","authors":"","doi":"10.1002/rcr2.70317","DOIUrl":"10.1002/rcr2.70317","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1002/rcr2.70275.].</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 8","pages":"e70317"},"PeriodicalIF":0.8,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12355037/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144875843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Respirology Case ReportsPub Date : 2025-08-13eCollection Date: 2025-08-01DOI: 10.1002/rcr2.70303
Hirohisa Horinouchi, Fumio Maitani, Jun Miyauchi
{"title":"A Case of Lung Volume Reduction Surgery in a Young Adult With Chronic Lung Disease.","authors":"Hirohisa Horinouchi, Fumio Maitani, Jun Miyauchi","doi":"10.1002/rcr2.70303","DOIUrl":"10.1002/rcr2.70303","url":null,"abstract":"<p><p>Chronic lung disease, characterised by impaired development and/or fibrotic changes in the lungs of preterm neonates, results in lifelong consequences that affect respiratory well-being. An 18-year-old male with chronic lung disease presented with shortness of breath upon exertion. Computed tomography revealed bilateral emphysema and a large bulla in the left lower lobe. Additionally, severe obstructive ventilatory impairment was observed and respiratory rehabilitation was ineffective in improving lung function. We performed lung volume reduction surgery on the left lower lobe, resulting in improved ventilatory function and exercise capability. This case shows that emphysematous changes in patients with chronic lung disease can be successfully treated with surgery.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 8","pages":"e70303"},"PeriodicalIF":0.8,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12350186/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144875842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Respirology Case ReportsPub Date : 2025-08-13eCollection Date: 2025-08-01DOI: 10.1002/rcr2.70312
Ella Brockwell-Mole, John D Blakey, Vidya V Navaratnam
{"title":"Loeys-Dietz Syndrome and Asthma: Pathophysiological Insights and Clinical Dilemmas.","authors":"Ella Brockwell-Mole, John D Blakey, Vidya V Navaratnam","doi":"10.1002/rcr2.70312","DOIUrl":"10.1002/rcr2.70312","url":null,"abstract":"<p><p>A 23-year-old man presented with a life-threatening asthma exacerbation following a respiratory infection. Although he had a childhood history of asthma, he had remained asymptomatic in adulthood and reported regular use of both vapes and marijuana. His medical history included Type 2 Loeys-Dietz syndrome (LDS), requiring multiple vascular surgeries, rendering standard asthma therapies relatively contraindicated. Due to the severity of his condition, nebulised beta-agonists were cautiously administered, and his beta-blocker therapy was substituted. Imaging and forced oscillation technique (FOT) demonstrated severe obstructive airways disease. Marked and persistent eosinophilia was noted. While asthma is a recognised comorbidity in LDS, earlier recognition and intervention, such as inhaled corticosteroids, smoking cessation support, and judicious use of beta-blockers, may have reduced the severity. Increased awareness of the prevalence and severity of asthma in LDS could support earlier diagnosis, preventive strategies and timely escalation of therapy, thereby reducing the risk of catastrophic respiratory events.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 8","pages":"e70312"},"PeriodicalIF":0.8,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12350188/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144875845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Respirology Case ReportsPub Date : 2025-08-12eCollection Date: 2025-08-01DOI: 10.1002/rcr2.70315
Jaejun Jeong, Min Kyun Kang
{"title":"Iatrogenic Pneumothorax Misdiagnosed as Spontaneous Pneumothorax.","authors":"Jaejun Jeong, Min Kyun Kang","doi":"10.1002/rcr2.70315","DOIUrl":"10.1002/rcr2.70315","url":null,"abstract":"<p><p>Pigtail catheter drainage is commonly performed for pleural effusion drainage. It should be noted that if the catheter is not connected to a closed system such as a chest bottle, outside air may enter; causing iatrogenic pneumothorax.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 8","pages":"e70315"},"PeriodicalIF":0.8,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12340230/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144838199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Surgical Resection for Rare Cases of Lung Cancer in Teenagers.","authors":"Ryusuke Sumiya, Takeshi Matsunaga, Yukio Watanabe, Mariko Fukui, Aritoshi Hattori, Takuo Hayashi, Kazuya Takamochi, Kenji Suzuki","doi":"10.1002/rcr2.70281","DOIUrl":"10.1002/rcr2.70281","url":null,"abstract":"<p><p>We experienced two cases of lung cancer in teenagers. Case 1 involved a 17-year-old never-smoking girl with no medical history. Chest computed tomography revealed a 9 × 7 mm ground-glass nodule in the left lung. Case 2 involved an 18-year-old man with no smoking history but bilateral pneumothorax. Chest computed tomography showed a 13 × 11 mm ground-glass nodule in the right lung. In both cases, thoracoscopic wedge resection was performed, and the tumours were pathologically diagnosed as adenocarcinoma in situ. There was no evidence of recurrence for 2 years in Case 1, and for 1.5 years in Case 2.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 8","pages":"e70281"},"PeriodicalIF":0.8,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12328035/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144795755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}