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Bronchiolar Adenoma/Ciliated Muconodular Papillary Tumour With a 17-Year Follow-Up: A Case Report. 细支气管腺瘤/纤毛黏结乳头状瘤17年随访1例。
IF 0.8
Respirology Case Reports Pub Date : 2025-08-27 eCollection Date: 2025-08-01 DOI: 10.1002/rcr2.70337
Yuri Hayashi, Eiji Ando, Yasuhiro Matsuo, Toshio Kasugai, Takuya Mikamo, Taro Takeda, Hideo Saka
{"title":"Bronchiolar Adenoma/Ciliated Muconodular Papillary Tumour With a 17-Year Follow-Up: A Case Report.","authors":"Yuri Hayashi, Eiji Ando, Yasuhiro Matsuo, Toshio Kasugai, Takuya Mikamo, Taro Takeda, Hideo Saka","doi":"10.1002/rcr2.70337","DOIUrl":"10.1002/rcr2.70337","url":null,"abstract":"<p><p>Bronchiolar Adenoma/Ciliated muconodular papillary tumour (BA/CMPT) is a rare pulmonary tumour that arises in the peripheral lung and exhibits both benign and malignant features. The classification and biological behaviour of BA/CMPT remain uncertain. We present a rare case of CMPT with a 17-year follow-up period.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 8","pages":"e70337"},"PeriodicalIF":0.8,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12391720/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Resilience Story of Managing Severe Obstructive Sleep Apnea With Hypoventilation Secondary to SELENON (SEPN1)-Related Myopathy. 管理SELENON （SEPN1）相关肌病继发的严重阻塞性睡眠呼吸暂停伴通气不足的恢复力故事。
IF 0.8
Respirology Case Reports Pub Date : 2025-08-27 eCollection Date: 2025-08-01 DOI: 10.1002/rcr2.70327
Raghad Alhajaji, Hamza O Dhafar, Muslim Mohammed Al Saadi, Ahmed S BaHammam
{"title":"Resilience Story of Managing Severe Obstructive Sleep Apnea With Hypoventilation Secondary to SELENON (SEPN1)-Related Myopathy.","authors":"Raghad Alhajaji, Hamza O Dhafar, Muslim Mohammed Al Saadi, Ahmed S BaHammam","doi":"10.1002/rcr2.70327","DOIUrl":"10.1002/rcr2.70327","url":null,"abstract":"<p><p>SELENON-related myopathy is a rare autosomal recessive disorder characterised predominantly by muscle weakness; sleep-disordered breathing and respiratory failure are frequent complications. We report a 15-year-old male with genetically confirmed SELENON-RM and a 12-year history of progressive sleep-related breathing disorders, managed with overnight volume-targeted pressure support (VtPS) positive airway pressure (PAP) plus supplemental oxygen. Longitudinal polysomnography (PSG) revealed evolution from mild REM-predominant hypopneas to severe obstructive sleep apnea (OSA) with hypoventilation. Despite the elimination of apneas and hypopneas on bilevel positive airway pressure with spontaneous-timed mode (BPAP-ST), persistent desaturation occurred during REM sleep. Transitioning to VtPS nocturnal PAP combined with oxygen-corrected hypoventilation normalised oxygen saturation across all sleep stages and abolished respiratory events.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 8","pages":"e70327"},"PeriodicalIF":0.8,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12381645/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Airway Foreign Body-Leave Nothing Behind. 呼吸道异物——不留痕迹。
IF 0.8
Respirology Case Reports Pub Date : 2025-08-26 eCollection Date: 2025-08-01 DOI: 10.1002/rcr2.70332
Jeffrey Ng, Christopher Thong, Kay Choong See
{"title":"Airway Foreign Body-Leave Nothing Behind.","authors":"Jeffrey Ng, Christopher Thong, Kay Choong See","doi":"10.1002/rcr2.70332","DOIUrl":"10.1002/rcr2.70332","url":null,"abstract":"<p><p>A middle-aged male presented with chronic cough, shortness of breath and fever. In the presence of wheeze and mild right-sided opacities on chest x-ray, he was treated for infective exacerbation of asthma with nebulised bronchodilators, antibiotics and steroids. Due to persistent wheeze, a contrasted computed tomography (CT) scan was done and revealed the presence of two endobronchial linear foreign body (FB) opacities, the second located more distally than the first. A rigid bronchoscopy-based technique under general anaesthesia was used to remove the first FB, and flexible bronchoscopy via endotracheal tube was used for the second FB in the same session. This case illustrates the tenets of airway FB diagnosis and management. The differential diagnosis of radiolucent airway FB needs to be considered in patients with chronic symptoms. Rigid and flexible bronchoscopy techniques are complementary. Peripheral lesions are more accessible by flexible bronchoscopy. Measures to ensure complete removal of FBs must be consistently incorporated into routine practice.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 8","pages":"e70332"},"PeriodicalIF":0.8,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12379834/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rare Case Report of Pulmonary Mucosa-Associated Lymphoid Tissue Lymphoma. 肺粘膜相关淋巴组织淋巴瘤罕见病例报告。
IF 0.8
Respirology Case Reports Pub Date : 2025-08-26 eCollection Date: 2025-08-01 DOI: 10.1002/rcr2.70284
Suzhen Yang, Qin Shen
{"title":"Rare Case Report of Pulmonary Mucosa-Associated Lymphoid Tissue Lymphoma.","authors":"Suzhen Yang, Qin Shen","doi":"10.1002/rcr2.70284","DOIUrl":"10.1002/rcr2.70284","url":null,"abstract":"<p><p>Bronchial mucosa-associated lymphoid tissue is the site of the uncommon malignancy known as mucosa-associated lymphoid tissue (MALT) lymphoma. Due to its lack of distinct clinical signs and imaging characteristics, it is frequently misdiagnosed and underdiagnosed. After receiving unsuccessful treatment for a lung infection or tuberculosis in multiple tertiary care hospitals, we report a male patient who had a solid lesion in his left upper lung for 18 years. The patient was ultimately diagnosed with pulmonary MALT lymphoma at our hospital through a CT-guided percutaneous lung biopsy using the Jiang technique (i.e., employing a laser-assisted guidance system in addition to the conventional CT guidance). It is vital to extend one's perspective, synthesise extrapulmonary signs, and work toward the conditions essential to get a high-quality biopsy specimen when an intrapulmonary lesion is hard to explain by general lung illnesses.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 8","pages":"e70284"},"PeriodicalIF":0.8,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12379836/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pulmonary Artery Pseudoaneurysm (PAA) in a Patient With Advanced Lung Cancer After Radiotherapy: A Potentially Fatal Complication. 晚期肺癌放疗后患者的肺动脉假性动脉瘤（PAA）：一种潜在的致命并发症。
IF 0.8
Respirology Case Reports Pub Date : 2025-08-21 eCollection Date: 2025-08-01 DOI: 10.1002/rcr2.70326
Josephine Coffey, Ayan Sabih
{"title":"Pulmonary Artery Pseudoaneurysm (PAA) in a Patient With Advanced Lung Cancer After Radiotherapy: A Potentially Fatal Complication.","authors":"Josephine Coffey, Ayan Sabih","doi":"10.1002/rcr2.70326","DOIUrl":"10.1002/rcr2.70326","url":null,"abstract":"<p><p>Pulmonary artery pseudoaneurysms (PAAs) are exceedingly uncommon. It is a life-threatening diagnosis, and often associated with poor long-term prognosis. We report a case of PAA in a 74-year-old man presenting with severe respiratory failure and haemoptysis with a history of advanced lung cancer. Though the intent was to manage the PAA with coil embolisation, this was unsuccessful and the patient passed away 72 h after hospital admission. There is limited evidence for treatment of PAA, and once a patient is symptomatic, has a high mortality.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 8","pages":"e70326"},"PeriodicalIF":0.8,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12370536/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pulmonary Cryptococcosis With Rapid Growth on Positron Emission Tomography/Computed Tomography. 肺隐球菌病与快速增长的正电子发射断层扫描/计算机断层扫描。
IF 0.8
Respirology Case Reports Pub Date : 2025-08-21 eCollection Date: 2025-08-01 DOI: 10.1002/rcr2.70322
Yosuke Fukuda, Naruhito Oda, Hironori Sagara, Akihiko Tanaka
{"title":"Pulmonary Cryptococcosis With Rapid Growth on Positron Emission Tomography/Computed Tomography.","authors":"Yosuke Fukuda, Naruhito Oda, Hironori Sagara, Akihiko Tanaka","doi":"10.1002/rcr2.70322","DOIUrl":"10.1002/rcr2.70322","url":null,"abstract":"<p><p>A 64-year-old woman with rheumatoid arthritis and asthma developed a rapid growth and uptake of <sup>18</sup>F-fluorodeoxyglucose (FDG)-avid lung nodule. Despite suspicion of malignancy, the biopsy confirmed pulmonary cryptococcosis (PC). Regardless of FDG uptake, PC should be considered in the differential diagnosis.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 8","pages":"e70322"},"PeriodicalIF":0.8,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12370445/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lorlatinib Achieved Rapid CNS Response in an 81-Year-Old NSCLC Patient With Performance Status Deterioration. Lorlatinib在81岁表现恶化的NSCLC患者中实现了快速中枢神经系统反应。
IF 0.8
Respirology Case Reports Pub Date : 2025-08-21 eCollection Date: 2025-08-01 DOI: 10.1002/rcr2.70320
Akina Nigi, Keisuke Iwamoto, Hidetoshi Itani, Shigeto Kondou
{"title":"Lorlatinib Achieved Rapid CNS Response in an 81-Year-Old NSCLC Patient With Performance Status Deterioration.","authors":"Akina Nigi, Keisuke Iwamoto, Hidetoshi Itani, Shigeto Kondou","doi":"10.1002/rcr2.70320","DOIUrl":"10.1002/rcr2.70320","url":null,"abstract":"<p><p>Lorlatinib may offer rapid CNS symptom and imaging improvement after alectinib failure, even in elderly ALK-positive NSCLC patients with declining performance status.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 8","pages":"e70320"},"PeriodicalIF":0.8,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12371122/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
COVID-19 Vaccine-Induced Severe Pneumonitis. COVID-19疫苗引起的严重肺炎。
IF 0.8
Respirology Case Reports Pub Date : 2025-08-21 eCollection Date: 2025-08-01 DOI: 10.1002/rcr2.70274
Tatsuro Suzuki, Hiromi Furuta, Misa Naganawa, Keiko Hayashi, Hiroko Kiyotoshi, Chiharu Ohta, Shigemitsu Ninomiya
{"title":"COVID-19 Vaccine-Induced Severe Pneumonitis.","authors":"Tatsuro Suzuki, Hiromi Furuta, Misa Naganawa, Keiko Hayashi, Hiroko Kiyotoshi, Chiharu Ohta, Shigemitsu Ninomiya","doi":"10.1002/rcr2.70274","DOIUrl":"10.1002/rcr2.70274","url":null,"abstract":"<p><p>Coronavirus disease 2019 (COVID-19) has resulted in global morbidity, mortality, and societal disruption. COVID-19 mRNA vaccination was mandatory in many countries for a period; however, severe adverse events have been observed in some individuals who received the vaccine. We report a case of COVID-19 mRNA vaccine-induced pneumonitis in a male patient whose cytokine levels were analysed prior to admission. His serum IgE level was high (347 U/mL), and several cytokines were elevated: TNFα was 1.2 pg/mL, IL-6 was 156 pg/mL, and IL-8 was 75.0 pg/mL. The patient developed severe respiratory failure requiring ventilatory support but recovered after steroid pulse therapy.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 8","pages":"e70274"},"PeriodicalIF":0.8,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12371123/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lenvatinib-Associated Non-Tuberculous Mycobacterial Pulmonary Disease: A Case Report. lenvatinib相关的非结核分枝杆菌肺病1例报告
IF 0.8
Respirology Case Reports Pub Date : 2025-08-20 eCollection Date: 2025-08-01 DOI: 10.1002/rcr2.70316
Qian Wang, Lili Du, Yiming Wang, Longhui Zhang
{"title":"Lenvatinib-Associated Non-Tuberculous Mycobacterial Pulmonary Disease: A Case Report.","authors":"Qian Wang, Lili Du, Yiming Wang, Longhui Zhang","doi":"10.1002/rcr2.70316","DOIUrl":"10.1002/rcr2.70316","url":null,"abstract":"<p><p>A 64-year-old man, with a history of hepatocellular carcinoma and long-term oral lenvatinib treatment, was hospitalised in our institution twice due to 'cough'. During hospitalisation, the patient underwent multiple bronchoscopies, with lavage fluid sent for pathogen testing, which returned negative results. Finally, <i>Mycobacterium kansasii</i> was detected via next-generation sequencing (NGS). Considering the patient's poor hepatic reserve, we decided against initiating targeted antimicrobial therapy and discontinued lenvatinib. Two months after stopping lenvatinib, the patient's symptoms of cough and chest tightness improved. A follow-up chest computed tomography (CT) on March 18, 2025, showed resolution of the lesions.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 8","pages":"e70316"},"PeriodicalIF":0.8,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12365607/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Partial Response to Nivolumab and Ipilimumab in a Patient With Malignant Pleural Mesothelioma and Pre-Existing Myasthenia Gravis Without Severe Flares or Immune-Related Adverse Events: A Case Report. Nivolumab和Ipilimumab对恶性胸膜间皮瘤和既往重症肌无力患者的部分应答，无严重症状或免疫相关不良事件：1例报告
IF 0.8
Respirology Case Reports Pub Date : 2025-08-19 eCollection Date: 2025-08-01 DOI: 10.1002/rcr2.70297
Mariko Higa, Tomoya Kuda, Yuichiro Ohya, Hidenori Kawasaki
{"title":"Partial Response to Nivolumab and Ipilimumab in a Patient With Malignant Pleural Mesothelioma and Pre-Existing Myasthenia Gravis Without Severe Flares or Immune-Related Adverse Events: A Case Report.","authors":"Mariko Higa, Tomoya Kuda, Yuichiro Ohya, Hidenori Kawasaki","doi":"10.1002/rcr2.70297","DOIUrl":"10.1002/rcr2.70297","url":null,"abstract":"<p><p>Detailed clinical data on the combination immune checkpoint inhibitor (ICI) therapy in patients with myasthenia gravis (MG) remain limited. We report a case of malignant pleural mesothelioma with previously undiagnosed ocular MG. Owing to hepatic dysfunction, reduced doses of nivolumab and ipilimumab were administered before confirmation of anti-acetylcholine receptor (AChR) antibody positivity. MG was diagnosed based on subtle ocular symptoms and serological tests. Prophylactic intravenous immunoglobulin and an acetylcholinesterase inhibitor were administered; combination therapy was discontinued owing to the risk of MG flare, but a partial tumour response was achieved. With disease progression, nivolumab monotherapy was reintroduced, and early steroid pulse therapy was administered owing to elevated creatine kinase, again inducing a partial response. Serological screening for anti-AChR antibodies may help prevent severe MG flares and immune-related adverse events. With caution, dose-reduced and limited-exposure ICI combination therapy may be feasible in selected patients with MG under appropriate prophylactic management.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 8","pages":"e70297"},"PeriodicalIF":0.8,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12364612/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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