用两性霉素 B 胆固醇硫酸盐复合物成功治疗食道-纵隔瘘伴发的大咯血和肺动脉假性动脉瘤:病例报告。

IF 0.8 Q4 RESPIRATORY SYSTEM
Respirology Case Reports Pub Date : 2024-10-14 eCollection Date: 2024-10-01 DOI:10.1002/rcr2.70047
Zhujun Chen, Jian He, Qin Huang, Peiqiang Liang, Liang Gong, Qiangzhong Pi
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引用次数: 0

摘要

食道-纵隔瘘并不常见。食管瘘可能表现为反复发作的肺炎。肺部感染可导致肺动脉假性动脉瘤(PAPs),尤其是真菌感染。肺动脉假性动脉瘤有破裂的危险,可能导致危及生命的咯血。我们报告了一例独特的病例,一名 45 岁的男性突然出现咳嗽、呼吸困难和咯血。支气管镜检查引发大咯血,需要进行紧急栓塞治疗。持续的咯血促使他接受了进一步的造影检查,结果发现他的脊柱旁有一个动脉瘤扩张和感染性病灶,这表明他患有食道-纵隔瘘。在开始使用两性霉素 B 胆固醇硫酸盐复合物治疗并关闭瘘管后,患者的咯血症状缓解,影像学检查也显示 PAP 消失。伏立康唑的长期治疗确保了病情的持续好转。该病例突出说明了真菌感染和 PAP 可能导致的瘘管的罕见性和严重性,强调了及时识别和积极治疗以获得良好疗效的重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Successful treatment of large hemoptysis and pseudoaneurysm of the pulmonary artery associated to oesophagomediastinal fistula with amphotericin B cholesterol sulfate complex: A case report.

Oesophagomediastinal fistula is uncommon. Oesophageal fistulas, may manifest as recurrent pneumonias. While pulmonary infections can lead to pulmonary artery pseudoaneurysms (PAPs), particularly in fungal infections. PAPs pose a rupture risk, potentially causing life-threatening hemoptysis. We report a unique case of a 45-year-old male who presented with sudden cough, dyspnea, and hemoptysis. Bronchoscopy triggered massive hemoptysis, necessitating emergency embolization. Persistent hemoptysis prompted further imaging, revealing an aneurysmal dilation located next to the spine and infectious lesions, suggesting an oesophagomediastinal fistula. After initiating therapy with Amphotericin B Cholesterol Sulfate Complex and fistula closure, the patient's hemoptysis resolved, with imaging resolution of the PAP. Long-term Voriconazole therapy ensured continued improvement. This case highlights the rarity and severity of such fistulas may be associated with fungal infections and PAPs, emphasizing the importance of prompt recognition, aggressive treatment for favourable outcomes.

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来源期刊
Respirology Case Reports
Respirology Case Reports RESPIRATORY SYSTEM-
CiteScore
1.40
自引率
0.00%
发文量
178
审稿时长
8 weeks
期刊介绍: Respirology Case Reports is an open-access online journal dedicated to the publication of original clinical case reports, case series, clinical images and clinical videos in all fields of respiratory medicine. The Journal encourages the international exchange between clinicians and researchers of experiences in diagnosing and treating uncommon diseases or diseases with unusual presentations. All manuscripts are peer-reviewed through a streamlined process that aims at providing a rapid turnaround time from submission to publication.
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