Respirology Case Reports最新文献

Prospective Case Series to Determine the Feasibility, Diagnostic Yield and Safety of Performing EBUS Guided Trans-Bronchial Mediastinal Cryobiopsy (EBUS-TBMC) of Lymph Nodes Using 1.1 mm Cryoprobe Through a Working Channel of Linear EBUS Bronchoscope Versus Conventional En-Bloc Cryobiopsy. 通过线性EBUS支气管镜工作通道使用1.1 mm冷冻探针对淋巴结进行经支气管纵隔低温活检（EBUS- tbmc）的可行性、诊断率和安全性的前瞻性病例系列研究，与传统的整体低温活检相比。

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Respirology Case Reports Pub Date : 2026-10-14 eCollection Date: 2026-10-01 DOI: 10.1002/rcr2.70784

Jolyn Ng, David Manners

{"title":"Prospective Case Series to Determine the Feasibility, Diagnostic Yield and Safety of Performing EBUS Guided Trans-Bronchial Mediastinal Cryobiopsy (EBUS-TBMC) of Lymph Nodes Using 1.1 mm Cryoprobe Through a Working Channel of Linear EBUS Bronchoscope Versus Conventional En-Bloc Cryobiopsy.","authors":"Jolyn Ng, David Manners","doi":"10.1002/rcr2.70784","DOIUrl":"https://doi.org/10.1002/rcr2.70784","url":null,"abstract":"EBUS-guided trans-bronchial mediastinal cryobiopsy (EBUS-TBMC) improves diagnostic yield over EBUS-TBNA but conventionally requires en-bloc removal of bronchoscope and frozen specimen, risking loss of airway control and procedural inefficiency. Retrieval of cryobiopsy specimens through-working channel (TWC) may address these limitations, but its feasibility and diagnostic adequacy are uncertain. Prospective evaluation was completed of 13 patients undergoing EBUS-TBMC at a single centre (August 2025 to January 2026). A 1.1 mm Erbe cryoprobe was advanced through an echobronchoscope with a 2.2 mm working channel (BF-UC190F, Olympus Medical, Japan) via needle tract formed via EBUS-TBNA. Fourteen lymph node stations underwent paired en-bloc and TWC biopsies. Paired biopsies were completed in 92.3% of targets. Median specimen size was equivalent (3 mm each; p = 0.197). Diagnostic yield was 93% (en-bloc) versus 79% (TWC); p = 0.48; versus 46% (EBUS-TBNA). There were no post procedural complications. TWC cryobiopsy using a 1.1 mm probe through a standard 2.2 mm working channel is feasible and safe compared to conventional en-bloc cryobiopsy.","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"14 10","pages":"e70784"},"PeriodicalIF":0.7,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13662630/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149196996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Bird's Nest Sign as an Initial Presentation of Primary Pulmonary B-Cell Non-Hodgkin Lymphoma With Plasmacytic Differentiation. 燕窝征是原发性肺b细胞非霍奇金淋巴瘤伴浆细胞分化的初始表现。

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Respirology Case Reports Pub Date : 2026-10-13 eCollection Date: 2026-10-01 DOI: 10.1002/rcr2.70783

Luong Dinh-Van, Hoang-Anh Nguyen-Cong, Phuong Duong-Minh, Nguyen Tran-Ngoc, Bich-Ngoc T Nguyen

{"title":"The Bird's Nest Sign as an Initial Presentation of Primary Pulmonary B-Cell Non-Hodgkin Lymphoma With Plasmacytic Differentiation.","authors":"Luong Dinh-Van, Hoang-Anh Nguyen-Cong, Phuong Duong-Minh, Nguyen Tran-Ngoc, Bich-Ngoc T Nguyen","doi":"10.1002/rcr2.70783","DOIUrl":"10.1002/rcr2.70783","url":null,"abstract":"The bird's nest sign (BNS) has been described as a sign on chest computed tomography (CT) in various pulmonary diseases. We report a rare case of primary pulmonary B-cell non-Hodgkin lymphoma with plasmacytic differentiation presenting with BNS, mimicking an invasive fungal disease at first. A 61-year-old Vietnamese man with a history of idiopathic thrombocytopenia and splenectomy 3 years prior to admission presented with prolonged dry cough, mild dyspnoea on exertion and chest discomfort for 3 weeks. His laboratory tests were unremarkable, but his chest CT showed bilateral consolidation with the BNS. After an unfavourable response to anti-fungal therapy, the second transthoracic lung biopsy confirmed the diagnosis of primary pulmonary B-cell non-Hodgkin lymphoma with plasmacytic differentiation. This case highlights the importance of considering lymphoma in the differential diagnosis of BNS when infection is excluded and concurrently seeking a confirmatory diagnosis with repeated diagnostic procedures when necessary.","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"14 10","pages":"e70783"},"PeriodicalIF":0.7,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13661188/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149185097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Erlotinib-Induced Pneumatosis Intestinalis: A Case Report and Review of Literature. 厄洛替尼致肠内肺病1例报告及文献复习。

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Respirology Case Reports Pub Date : 2026-10-06 eCollection Date: 2026-10-01 DOI: 10.1002/rcr2.70776

Shunsuke Saito, Koki Nakashima, Kaede Yokoyama, Ai Takeuchi, Makiko Yamaguchi, Yukihiro Umeda, Yuko Waseda

引用次数: 0

Localized Tracheobronchial Transthyretin Amyloidosis Diagnosed After Hemoptysis: A Case Report. 咯血后诊断的局限性气管支气管转甲状腺蛋白淀粉样变1例。

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Respirology Case Reports Pub Date : 2026-10-06 eCollection Date: 2026-10-01 DOI: 10.1002/rcr2.70781

Koichi Inoue, Yasumasa Tanaka, Masahiro Yanagi, Haruhiko Michimata, Yuta Nagahisa, Shun Kondoh

{"title":"Localized Tracheobronchial Transthyretin Amyloidosis Diagnosed After Hemoptysis: A Case Report.","authors":"Koichi Inoue, Yasumasa Tanaka, Masahiro Yanagi, Haruhiko Michimata, Yuta Nagahisa, Shun Kondoh","doi":"10.1002/rcr2.70781","DOIUrl":"10.1002/rcr2.70781","url":null,"abstract":"Pulmonary involvement in transthyretin amyloidosis (ATTR) is rare, and tracheobronchial involvement is particularly uncommon. We report a case of wild-type ATTR amyloidosis presenting with hemoptysis in a 66-year-old woman with dyspnea. Chest computed tomography revealed bronchial wall thickening and infiltrative opacities. Bronchoscopy showed irregular mucosal lesions extending from the trachea to both bronchi. Histopathological examination of bronchial biopsy specimens showed Congo red-positive deposits, and immunohistochemistry confirmed transthyretin, establishing the diagnosis of ATTR amyloidosis. Systemic evaluation and genetic testing excluded systemic and hereditary disease, leading to a diagnosis of localized wild-type ATTR. Bronchial aspirate cultures yielded Aspergillus fumigatus and Mycobacterium mucogenicum, and antifungal therapy was administered for a suspected concomitant airway infection. This rare presentation of tracheobronchial-localized ATTR amyloidosis underscores the importance of considering amyloidosis in the differential diagnosis of hemoptysis and the diagnostic role of bronchoscopy.","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"14 10","pages":"e70781"},"PeriodicalIF":0.7,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13641974/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149128927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Persistent SARS-CoV-2 RNA Positivity in a Chronic Lymphocytic Leukaemia Patient for 127 Days After Disease Onset: A Case Report. 慢性淋巴细胞白血病患者发病后127天持续SARS-CoV-2 RNA阳性1例报告

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Respirology Case Reports Pub Date : 2026-10-05 eCollection Date: 2026-10-01 DOI: 10.1002/rcr2.70767

Farnoosh Khamseh, Amir-Hossein Moghtader-Mojdehi, Zahra Nemati, Mehrdad Haghighi

{"title":"Persistent SARS-CoV-2 RNA Positivity in a Chronic Lymphocytic Leukaemia Patient for 127 Days After Disease Onset: A Case Report.","authors":"Farnoosh Khamseh, Amir-Hossein Moghtader-Mojdehi, Zahra Nemati, Mehrdad Haghighi","doi":"10.1002/rcr2.70767","DOIUrl":"10.1002/rcr2.70767","url":null,"abstract":"Chronic lymphocytic leukaemia (CLL) is characterised by profound immune dysfunction, increasing susceptibility to severe and persistent infections such as COVID-19. Our case report presents a 69-year-old woman with CLL who exhibited a prolonged duration of SARS-CoV-2 RT-PCR positivity-127 days-despite receiving standard therapies including dexamethasone and remdesivir. The patient, previously on maintenance ibrutinib, presented with fever and ground-glass opacities on CT scan and laboratory findings revealed marked lymphocytosis, elevated inflammatory markers and hepatic and renal dysfunction. Persistent viral shedding was attributed to CLL-associated hypogammaglobulinemia and chemotherapy-induced immunosuppression, resulting in impaired antibody response and eventual fatal hypoxemia. This case underscores the challenges of managing COVID-19 in CLL patients and highlights the need for individualised treatment strategies, including consideration of monoclonal antibodies and immunoglobulin replacement, to address prolonged viral replication and improve clinical outcomes in this vulnerable population.","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"14 10","pages":"e70767"},"PeriodicalIF":0.7,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13639249/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149116158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Giant Intrapulmonary Solitary Fibrous Tumour With a Possible Liver Metastasis: A Rare Case. 巨大肺内孤立性纤维性肿瘤并可能有肝转移：一例罕见病例。

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Respirology Case Reports Pub Date : 2026-10-01 DOI: 10.1002/rcr2.70754

Desdiani Desdiani, Nurjati Chairani Siregar, Asysyukriati Prawiro, Khansa Kiasati Chandra Syahbunan

{"title":"Giant Intrapulmonary Solitary Fibrous Tumour With a Possible Liver Metastasis: A Rare Case.","authors":"Desdiani Desdiani, Nurjati Chairani Siregar, Asysyukriati Prawiro, Khansa Kiasati Chandra Syahbunan","doi":"10.1002/rcr2.70754","DOIUrl":"https://doi.org/10.1002/rcr2.70754","url":null,"abstract":"Intrapulmonary solitary fibrous tumours (SFTs) are exceptionally rare mesenchymal neoplasms, particularly when presenting as giant thoracic masses. We report a case of a 57-year-old woman with progressive chest pain and dyspnoea who initially presented with pleural effusion and hypoglycaemia and received empirical anti-tuberculosis therapy without improvement. Contrast-enhanced CT revealed a left lower lobe mass enlarging to 11 × 16.5 × 15.2 cm on repeat imaging, with rightward cardiac displacement, pericardial effusion and a hepatic nodule suspicious for metastasis to the liver. Core needle biopsy revealed a low-grade spindle cell neoplasm. Immunohistochemistry revealed diffuse STAT6 positivity, partial CD34 positivity, Ki-67 < 5%, and negativity for CK7, desmin, SMA and S100, supporting the diagnosis of SFT. Following a multidisciplinary evaluation, six cycles of systemic chemotherapy were administered, and the patient remained clinically stable. This case highlights the diagnostic challenges of giant intrapulmonary SFT and the pivotal role of STAT6 immunohistochemistry in establishing the diagnosis.","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"14 10","pages":"e70754"},"PeriodicalIF":0.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13631407/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149116141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bronchiectasis as the Sentinel Manifestation of ANCA-Associated Vasculitis: A Case Report and Literature Review. 支气管扩张是anca相关血管炎的前哨表现：1例报告及文献复习。

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Respirology Case Reports Pub Date : 2026-10-01 DOI: 10.1002/rcr2.70777

Andrew Kim, Celine Vartany, Siddhanth Hegde, Kristie Lau, Lynette Tatosyan, Brannen Liang

{"title":"Bronchiectasis as the Sentinel Manifestation of ANCA-Associated Vasculitis: A Case Report and Literature Review.","authors":"Andrew Kim, Celine Vartany, Siddhanth Hegde, Kristie Lau, Lynette Tatosyan, Brannen Liang","doi":"10.1002/rcr2.70777","DOIUrl":"https://doi.org/10.1002/rcr2.70777","url":null,"abstract":"Bronchiectasis in ANCA-associated vasculitis (AAV) is usually attributed to structural damage from established disease. We report a 74-year-old woman with 7 years of culture-negative bronchiectasis, incompletely responsive to corticosteroids, in whom AAV was diagnosed after she developed palpable purpura, haemoptysis, hematuria and acute kidney injury. MPO-ANCA was markedly elevated (250.2 U/mL; reference < 1.0 U/mL) with PR3-ANCA negative. Renal biopsy showed pauci-immune crescentic glomerulonephritis, Berden focal class (one of 14 glomeruli with a cellular crescent). Induction with intravenous methylprednisolone and rituximab produced substantial renal recovery (eGFR nadir 23, stabilizing at 60 mL/min/1.73 m2 at 15 months) and near-complete resolution of the pulmonary consolidations. This case describes an airway-first AAV phenotype. She met none of the trigger features that current guidelines use to prompt autoimmune screening, identifying a diagnostic blind spot in progressive culture-negative bronchiectasis without systemic features.","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"14 10","pages":"e70777"},"PeriodicalIF":0.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13630863/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149116036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Environmental Asbestos Exposure as a Possible Pathway to Early-Onset Pleural Mesothelioma: A Case From Afghanistan and Pakistan to London. 环境石棉暴露作为早发性胸膜间皮瘤的可能途径：从阿富汗和巴基斯坦到伦敦的一个病例。

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Respirology Case Reports Pub Date : 2026-09-30 eCollection Date: 2026-10-01 DOI: 10.1002/rcr2.70774

Sophie Mounouchos, Asmita Aggarwal, Asaad Ahmed Nafees, Emma Johnson, Paul Cullinan, Carl Reynolds

{"title":"Environmental Asbestos Exposure as a Possible Pathway to Early-Onset Pleural Mesothelioma: A Case From Afghanistan and Pakistan to London.","authors":"Sophie Mounouchos, Asmita Aggarwal, Asaad Ahmed Nafees, Emma Johnson, Paul Cullinan, Carl Reynolds","doi":"10.1002/rcr2.70774","DOIUrl":"https://doi.org/10.1002/rcr2.70774","url":null,"abstract":"Malignant pleural mesothelioma (MPM) is strongly associated with occupational asbestos exposure and typically presents decades after exposure, in older men. The association of MPM with environmental exposure and genetic susceptibility is less recognised. We report a case of a 40-year-old man presenting in London with dyspnoea, weight loss and a persistent right-sided pleural effusion following hospitalisation for pneumonia. Imaging showed circumferential nodular thickening of the right pleura with lymph node involvement, and histopathology was in keeping with epithelioid-type MPM. With no known occupational exposure, childhood residences in Kabul, Afghanistan and Peshawar, Pakistan, where high levels of environmental asbestos are documented, represent plausible sources of environmental exposure. As a result of migration from regions with high environmental asbestos exposure, clinicians in high-income countries may encounter increasing numbers of patients with MPM due to non-occupational asbestos exposure.","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"14 10","pages":"e70774"},"PeriodicalIF":0.7,"publicationDate":"2026-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13626864/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149116131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chronic Eosinophilic Pneumonia: A Diagnostic Challenge With Atypical Bronchoalveolar Lavage Findings and an Organizing Pneumonia Pattern. 慢性嗜酸性粒细胞性肺炎：非典型支气管肺泡灌洗结果和组织型肺炎的诊断挑战。

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Respirology Case Reports Pub Date : 2026-09-30 eCollection Date: 2026-10-01 DOI: 10.1002/rcr2.70780

Yang-Tai Lin, Wei-Fan Ou, Sha-Yen Liang, Yu-Hsuan Hu, Wan-Ching Chen, Ming-Cheng Chan

{"title":"Chronic Eosinophilic Pneumonia: A Diagnostic Challenge With Atypical Bronchoalveolar Lavage Findings and an Organizing Pneumonia Pattern.","authors":"Yang-Tai Lin, Wei-Fan Ou, Sha-Yen Liang, Yu-Hsuan Hu, Wan-Ching Chen, Ming-Cheng Chan","doi":"10.1002/rcr2.70780","DOIUrl":"https://doi.org/10.1002/rcr2.70780","url":null,"abstract":"Chronic eosinophilic pneumonia (CEP) is a rare eosinophilic lung disease. We report a 61-year-old man with asthma who presented with progressive exertional dyspnoea for 2 months and worsening productive cough for 2 weeks. Peripheral blood eosinophilia was 15% (1314 cells/μL), and chest computed tomography showed bilateral peripheral, upper-lobe-predominant opacities. Bronchoalveolar lavage (BAL) revealed marked neutrophil predominance (85%) with only 6% eosinophils. Empirical antibiotics produced no clinical or radiographic improvement. Because clinical and radiological suspicion for CEP remained high despite discordant BAL findings, surgical lung biopsy was performed, demonstrating prominent eosinophilic infiltration with an organizing pneumonia pattern, supporting a diagnosis of CEP. The patient responded well to systemic corticosteroids. This case highlights the role of surgical lung biopsy in suspected CEP with atypical BAL findings and illustrates that organizing pneumonia may occur within the histopathological spectrum of CEP.","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"14 10","pages":"e70780"},"PeriodicalIF":0.7,"publicationDate":"2026-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13626768/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149116048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Long-Term Survival Following Nivolumab Treatment in Pulmonary Tumour Thrombotic Microangiopathy Associated With Cancer of Unknown Primary: A Case Report. 纳武单抗治疗与未知原发癌症相关的肺肿瘤血栓性微血管病的长期生存率：1例报告。

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Respirology Case Reports Pub Date : 2026-09-30 eCollection Date: 2026-10-01 DOI: 10.1002/rcr2.70763

Kosuke Fujishima, Jun Osugi, Satoshi Noma, Mitsunori Higuchi, Hiroyuki Suzuki

{"title":"Long-Term Survival Following Nivolumab Treatment in Pulmonary Tumour Thrombotic Microangiopathy Associated With Cancer of Unknown Primary: A Case Report.","authors":"Kosuke Fujishima, Jun Osugi, Satoshi Noma, Mitsunori Higuchi, Hiroyuki Suzuki","doi":"10.1002/rcr2.70763","DOIUrl":"https://doi.org/10.1002/rcr2.70763","url":null,"abstract":"Pulmonary tumour thrombotic microangiopathy (PTTM) is a rare but frequently fatal condition characterized by rapidly progressive pulmonary hypertension and right heart failure caused by tumour microemboli in the pulmonary vasculature. We report the case of a 64-year-old man who presented with rapidly progressive respiratory failure. Chest computed tomography demonstrated centrilobular nodules and a tree-in-bud (TIB) pattern. Pulmonary perfusion scintigraphy and transthoracic echocardiography suggested pulmonary hypertension with multiple peripheral perfusion defects, raising strong clinical suspicion for PTTM. Transbronchial lung biopsy (TBLB) revealed TTF-1-positive adenocarcinoma, although the primary tumour site remained undetermined. Based on these findings, clinically suspected PTTM was diagnosed and nivolumab monotherapy was promptly initiated as systemic treatment for the underlying malignancy. Despite transient severe deterioration, the patient's respiratory function improved markedly, and he has remained progression-free for more than 3 years. This case highlights the importance of early clinical recognition of PTTM and prompt initiation of appropriate systemic therapy, even before definitive identification of the primary tumour when clinically warranted.","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"14 10","pages":"e70763"},"PeriodicalIF":0.7,"publicationDate":"2026-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13627871/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149116211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0