Respirology Case ReportsPub Date : 2024-11-06eCollection Date: 2024-11-01DOI: 10.1002/rcr2.70053
Nina M Janssen, Rein Posthuma, Sophie Kienhorst, Michiel A G E Bannier, Ulrich C Lalji, Frits M E Franssen, Roy T M Sprooten
{"title":"Successful treatment of a persistent air leak with an endobronchial valve in a 17-year-old patient with necrotizing pneumonia.","authors":"Nina M Janssen, Rein Posthuma, Sophie Kienhorst, Michiel A G E Bannier, Ulrich C Lalji, Frits M E Franssen, Roy T M Sprooten","doi":"10.1002/rcr2.70053","DOIUrl":"10.1002/rcr2.70053","url":null,"abstract":"<p><p>Pleural empyema is a severe condition associated with high morbidity and mortality. Treatment usually consists of pleural drainage with chest tube or surgery, in combination with antimicrobial treatment. Severe pneumonia can evolve in a necrotizing pneumonia, given a higher susceptibility to the occurrence of bronchopleural fistulas with persistent air leaks. This complicates recovery, and surgery may not always be the optimal treatment. We present a case involving a 17-year-old female patient who experienced a post-operative persistent air leak due to necrotizing pneumonia after video-assisted thoracic surgery decortication for empyema, which was successfully treated using an endobronchial valve. After 6 months the valve was removed without complications. Follow-up imaging and lung function revealed a limited area of atelectasis and minimal pleural thickening with normal lung volumes.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11540447/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142590971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Respirology Case ReportsPub Date : 2024-11-03eCollection Date: 2024-11-01DOI: 10.1002/rcr2.70058
Dylan Beinart, Siaw Ming Chai, Olivia Walsh, Sanjay Ramakrishnan, John Blakey
{"title":"Watchful waiting in laryngo-tracheobronchial amyloid: A case report.","authors":"Dylan Beinart, Siaw Ming Chai, Olivia Walsh, Sanjay Ramakrishnan, John Blakey","doi":"10.1002/rcr2.70058","DOIUrl":"10.1002/rcr2.70058","url":null,"abstract":"<p><p>We report the long term follow up of a now 66-year-old male with laryngo-tracheobronchial amyloidosis. The patient initially presented with dysphonia and dyspnoea. He was diagnosed with laryngeal reflux and asthma. Seven years later, the patient underwent cross sectional thoracic imaging showing diffuse thickening of the distal trachea and proximal main bronchi. The patient's FEV1 and FVC remained stable over 13 years and no intervention was required.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11532455/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142577023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Respirology Case ReportsPub Date : 2024-10-30eCollection Date: 2024-11-01DOI: 10.1002/rcr2.70059
Yunjie Cui, Bo Wang, Cuiping Yang
{"title":"Imaging of acute dissemination of tuberculosis caused by alveolar lavage surgery in endobronchial tuberculosis characterized by caseous necrosis.","authors":"Yunjie Cui, Bo Wang, Cuiping Yang","doi":"10.1002/rcr2.70059","DOIUrl":"10.1002/rcr2.70059","url":null,"abstract":"<p><p>Large amount of caseating overlying on bronchus were detected under bronchoscopy in our case. Bronchoalveolar lavage is a major method for diagnosing tuberculosis (TB). TB dissemination caused by bronchoalveolar lavage is very rare. In this case, the patient developed fever after bronchoalveolar lavage and CT confirmed acute dissemination. This might be related to caseating EBTB.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11522607/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142548199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Respirology Case ReportsPub Date : 2024-10-30eCollection Date: 2024-11-01DOI: 10.1002/rcr2.70055
Menna Megahed, Roozbeh Sharif, Yazan Abdeen
{"title":"Synchronous bilateral typical pulmonary carcinoid tumours diagnosed by robotic navigation bronchoscopy: A unique case.","authors":"Menna Megahed, Roozbeh Sharif, Yazan Abdeen","doi":"10.1002/rcr2.70055","DOIUrl":"10.1002/rcr2.70055","url":null,"abstract":"<p><p>Pulmonary carcinoids are uncommon malignant neoplasms, believed to derive from specialized neuroendocrine cells known as Kulchitsky cells. We evaluated a 69-year-old female presenting symptoms consistent with carcinoid syndrome, such as intermittent flushing and diarrhoea, along with complaints of shortness of breath and cough. Imaging revealed bilateral lung nodules, confirmed by biopsy to be carcinoid tumours. The treatment of choice for carcinoid tumours is complete surgical resection. Nonetheless, individualized management plans are crafted based on the tumour's location and the patient's respiratory function as these present challenges to anatomical resection of tumours.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11522608/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142548201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Respirology Case ReportsPub Date : 2024-10-29eCollection Date: 2024-11-01DOI: 10.1002/rcr2.70057
Kim Hoong Yap, Albert Yick Hou Lim, Biju Thomas, Carine Bonnard, Emmanuelle Szenker-Ravi, Yan Ling Chong, Sudipto Roy, Bruno Reversade
{"title":"Novel CYCLIN-O pathogenic variants in a patient presenting with bronchiectasis secondary to reduced generation of multiple motile cilia.","authors":"Kim Hoong Yap, Albert Yick Hou Lim, Biju Thomas, Carine Bonnard, Emmanuelle Szenker-Ravi, Yan Ling Chong, Sudipto Roy, Bruno Reversade","doi":"10.1002/rcr2.70057","DOIUrl":"10.1002/rcr2.70057","url":null,"abstract":"<p><p>Reduced generation of multiple motile cilia (RGMC) represents a rare variant of Primary Ciliary Dyskinesia (PCD), associated with <i>CYCLIN-O (CCNO)</i> mutations. We report a novel compound mutation in the <i>CCNO</i> gene in an adult Chinese Singaporean exhibiting chronic productive cough since childhood and recurrent sino-pulmonary infections. Low nasal nitric oxide and bronchiectasis suggests PCD. Bronchoscopy for epithelial and nasal brushings for ciliary studies were repeated after adequate treatment of lower respiratory tract infections. Demonstration of oligo-cilia via transmission electron microscopy, and detection of <i>CCNO</i> mutation through genetic analysis were utilized to diagnose RGMC. Repeated courses of antibiotics including nebulised antibiotics were used to treat recurrent infections and exacerbations. Airway clearance techniques, immunizations and collaboration with otorhinolaryngologist form part of the long-term management. Heightened clinical suspicion and adherence to established diagnostic algorithms are essential for timely recognition of this entity.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11519382/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142548200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Milk in the intercostal tube: Revealing Boerhaave syndrome.","authors":"Manasa Kuthadi, Surendar Reddy K, Narayana Mood, Alekya Papayagari, Rakesh Gattu","doi":"10.1002/rcr2.70056","DOIUrl":"10.1002/rcr2.70056","url":null,"abstract":"<p><p>We present an uncommon pathology of Boerhaave's syndrome and its fatal outcome in a 77-year-old man who presented to the emergency room with loss of consciousness and a history of chronic cough that had increased in intensity over the past week. Radiological investigations revealed bilateral pleural effusion, initially pointing to a transudative aetiology. Diagnostic pleural aspiration showed an exudative effusion with high amylase, and an intercostal drainage tube was inserted for the left massive effusion. Contrary to the initial provisional diagnosis, the discovery of ingested milk in the intercostal drainage tube raised suspicion of Boerhaave's syndrome. Around 90% of perforations occur on the left side of the distal oesophagus, presenting as a pleural effusion on the left side. Less than 10% of patients experience bilateral pleural effusions. This patient's clinical presentation, which led to the diagnosis, is of interest. Unfortunately, he eventually lapsed into sepsis and succumbed.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11513256/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142523343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Respirology Case ReportsPub Date : 2024-10-24eCollection Date: 2024-10-01DOI: 10.1002/rcr2.70036
Sameer Bansal, Ramesh Chokhani, Ravindra M Mehta
{"title":"Silicone blockers for bronchial leaks: Expanding the literature base with a larger and longer experience in this complex entity.","authors":"Sameer Bansal, Ramesh Chokhani, Ravindra M Mehta","doi":"10.1002/rcr2.70036","DOIUrl":"https://doi.org/10.1002/rcr2.70036","url":null,"abstract":"<p><p>Innovative techniques using silicone blockers for bronchial leaks where options are few, stakes are high and favourable outcomes can be achieved in a short span of time.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11499703/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142510137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Respirology Case ReportsPub Date : 2024-10-21eCollection Date: 2024-10-01DOI: 10.1002/rcr2.70054
Seyram M Wordui, Shivani Singh, Tanyia Pillay, Marco Zampoli, Adriaan Daniels, Andre Brooks, Aneesa Vanker, Diane Gray
{"title":"A case of cytomegalovirus cystic lung disease and review of literature.","authors":"Seyram M Wordui, Shivani Singh, Tanyia Pillay, Marco Zampoli, Adriaan Daniels, Andre Brooks, Aneesa Vanker, Diane Gray","doi":"10.1002/rcr2.70054","DOIUrl":"https://doi.org/10.1002/rcr2.70054","url":null,"abstract":"<p><p>A 31-week gestation male infant with respiratory distress since day of delivery had lobectomy at 8 weeks of age for symptomatic, suspected congenital pulmonary airway malformation (CPAM). Histology of resected lung showed cytomegalovirus (CMV) inclusion bodies and emphysematous changes. The infant was treated with antiviral therapy with improvement in symptoms. CMV infection of the lung should be considered in any neonate presenting with lung cysts.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11493753/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142510136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pulmonary <i>Pasteurella multocida</i> infection with tree-in-bud appearance.","authors":"Hirokazu Tokuyasu, Katsunori Arai, Yuriko Sueda, Hiromitsu Sakai, Akira Yamasaki","doi":"10.1002/rcr2.70043","DOIUrl":"10.1002/rcr2.70043","url":null,"abstract":"<p><p>Here, we report a case of zoonosis pulmonary <i>Pasteurella multocida</i> infection with a tree-in-bud appearance. In cases showing a tree-in-bud appearance on chest CT images, pulmonary <i>P. multocida</i> infection should be considered in the differential diagnosis, especially in patients with pets.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11493101/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142477287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Respirology Case ReportsPub Date : 2024-10-17eCollection Date: 2024-10-01DOI: 10.1002/rcr2.70051
Zeinab El Mawla, Ghinwa Hammoud, Racha Abed El Hamid, Abbas Zreik, Ali Tfayli, Bassam Mansour
{"title":"Fatal outcome in isolated Pauci-immune pulmonary capillaritis: A case report.","authors":"Zeinab El Mawla, Ghinwa Hammoud, Racha Abed El Hamid, Abbas Zreik, Ali Tfayli, Bassam Mansour","doi":"10.1002/rcr2.70051","DOIUrl":"https://doi.org/10.1002/rcr2.70051","url":null,"abstract":"<p><p>Isolated Pauci-immune pulmonary capillaritis (IPIPC) is a rare form of small vessel vasculitis that affects only the lungs, causing inflammation of pulmonary capillaries and potentially leading to severe outcomes like alveolar haemorrhage. A 23-year-old woman with a prior diagnosis of rheumatoid arthritis presented with hemoptysis and respiratory distress, ultimately diagnosed with IPIPC. Despite treatment with high-dose steroids and intravenous immunoglobulin, her condition deteriorated, resulting in respiratory failure and death. IPIPC often lacks systemic symptoms and ANCA positivity, complicating diagnosis and treatment. Imaging, bronchoscopy, and histopathology are key for diagnosis, while management typically involves corticosteroids and possibly immunosuppressives. The case underscores the challenges in identifying and treating IPIPC, highlighting the importance of early intervention to improve prognosis, even though complications can still lead to significant respiratory issues and mortality.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11486526/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142477283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}