Respirology Case ReportsPub Date : 2025-04-07eCollection Date: 2025-04-01DOI: 10.1002/rcr2.70129
Vanessa Wong, Sathya Balaguruswamy, Bapti Roy
{"title":"Autologous Blood Pleurodesis Through an Indwelling Pleural Catheter for the Management of Prolonged Air Leak in a Malignant Hydropneumothorax.","authors":"Vanessa Wong, Sathya Balaguruswamy, Bapti Roy","doi":"10.1002/rcr2.70129","DOIUrl":"10.1002/rcr2.70129","url":null,"abstract":"<p><p>The British Thoracic Society guidelines recommend a surgical opinion in cases of prolonged air leak or failure of lung re-expansion after 3-5 days. The management of prolonged air leak in non-surgical candidates often proves to be more challenging, with no expert consensus guidelines on treatment options. There is a paucity of data for the treatment of patients with a prolonged air leak in the setting of a hydropneumothorax, who are not suitable surgical candidates. We present the case of a novel treatment approach for an 89-year-old male with a symptomatic, large malignant pleural effusion treated initially with a routine chest tube drainage. Subsequent management was complicated by a hydropneumothorax with a persistent and large volume air leak. He was treated successfully with an autologous blood pleurodesis using an indwelling pleural catheter. Here we describe a novel management approach for persistent air-leak in the setting of a malignant hydropneumothorax. Autologous blood pleurodesis via an indwelling pleural catheter appears to be a safe and effective treatment option for non-surgical candidates and allows ongoing long-term drainage of a malignant effusion and air leak.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 4","pages":"e70129"},"PeriodicalIF":0.8,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11973726/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143804434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Respirology Case ReportsPub Date : 2025-04-07eCollection Date: 2025-04-01DOI: 10.1002/rcr2.70143
Zhujun Chen, Tingting Liu, Haiqin Guo, Yan Zhou, Hailing Duan, Bingjing Zhu, Yongfeng Chen, Liang Gong
{"title":"Endotracheal Actinomycosis Combined With Mucormycosis: A Case Report and Literature Review.","authors":"Zhujun Chen, Tingting Liu, Haiqin Guo, Yan Zhou, Hailing Duan, Bingjing Zhu, Yongfeng Chen, Liang Gong","doi":"10.1002/rcr2.70143","DOIUrl":"https://doi.org/10.1002/rcr2.70143","url":null,"abstract":"<p><p>Actinomycosis and mucormycosis are rare infections, and their coexistence in a single host is extremely uncommon. Actinomycosis of the trachea is a chronic septic condition caused by actinomycete infection, often misdiagnosed due to the difficulty of obtaining microbiological evidence. Mucormycosis, an invasive fungal infection, is characterised by rapid progression and high mortality, commonly occurring in immunocompromised patients. A 58-year-old woman with poorly controlled diabetes presented with a whitish mass in the main bronchus, identified via bronchoscopy. Pathological biopsy confirmed actinomycosis with mucormycosis. After treatment with cryotherapy, Holmium Laser, amphotericin B, and penicillin, she was successfully discharged. When imaging suggests intratracheal lesions, early bronchoscopy and etiological investigation are crucial to avoid misdiagnosis.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 4","pages":"e70143"},"PeriodicalIF":0.8,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11975617/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143812475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Respirology Case ReportsPub Date : 2025-04-07eCollection Date: 2025-04-01DOI: 10.1002/rcr2.70174
Jaejun Jeong, Min Kyun Kang
{"title":"Pleurodesis With 50% Dextrose for Old Patient With Secondary Spontaneous Pneumothorax: Relatively Safe and Efficient Method.","authors":"Jaejun Jeong, Min Kyun Kang","doi":"10.1002/rcr2.70174","DOIUrl":"10.1002/rcr2.70174","url":null,"abstract":"<p><p>We recommend that even in old patients with severe COPD, who could not tolerate chemical pleurodesis, pleurodesis with 50% dextrose should be considered since it is a relatively safe and efficient method.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 4","pages":"e70174"},"PeriodicalIF":0.8,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11973728/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143804437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Respirology Case ReportsPub Date : 2025-04-07eCollection Date: 2025-04-01DOI: 10.1002/rcr2.70172
Pranjal Rai, Vasundhara Patil
{"title":"Mediastinal Germ Cell Tumour in an Infant With Respiratory Distress.","authors":"Pranjal Rai, Vasundhara Patil","doi":"10.1002/rcr2.70172","DOIUrl":"10.1002/rcr2.70172","url":null,"abstract":"<p><p>Mediastinal teratomas, though rare in infants, can present with respiratory distress. Imaging plays a crucial role in diagnosis, with CT and PET aiding in characterisation. Surgical resection is the treatment of choice, with chemotherapy reserved for immature components. Early diagnosis is essential to prevent complications and optimise outcomes.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 4","pages":"e70172"},"PeriodicalIF":0.8,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11973729/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143804436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Respirology Case ReportsPub Date : 2025-04-03eCollection Date: 2025-04-01DOI: 10.1002/rcr2.70167
Bryan F Vaca-Cartagena, Sebastian A Mikulic, Sofia Valdes-Camacho, Alejandra Yu Lee-Mateus, Alanna Barrios-Ruiz, Rodrigo Funes-Ferrada, Elise N Anderson, Sebastian Fernandez-Bussy, Samuel D Mays, Cody A Trenary, David Abia-Trujillo
{"title":"Using Endobronchial Valves to Manage Pneumomediastinum.","authors":"Bryan F Vaca-Cartagena, Sebastian A Mikulic, Sofia Valdes-Camacho, Alejandra Yu Lee-Mateus, Alanna Barrios-Ruiz, Rodrigo Funes-Ferrada, Elise N Anderson, Sebastian Fernandez-Bussy, Samuel D Mays, Cody A Trenary, David Abia-Trujillo","doi":"10.1002/rcr2.70167","DOIUrl":"10.1002/rcr2.70167","url":null,"abstract":"<p><p>Endobronchial valves have a variety of potential applications, from lung volume reduction in patients with severe emphysema to closing cavities in those with drug-resistant tuberculosis. This report presents two cases in which endobronchial valves were effectively used to treat pneumomediastinum.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 4","pages":"e70167"},"PeriodicalIF":0.8,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11966558/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Respirology Case ReportsPub Date : 2025-03-25eCollection Date: 2025-03-01DOI: 10.1002/rcr2.70158
Kan Zhang, Jie Gao, Xiaofei Liu, Dingyun Song, Tiemei Zhao
{"title":"Pulmonary Light Chain Deposition With Sjögren Syndrome: A Case Report and Literature Review.","authors":"Kan Zhang, Jie Gao, Xiaofei Liu, Dingyun Song, Tiemei Zhao","doi":"10.1002/rcr2.70158","DOIUrl":"10.1002/rcr2.70158","url":null,"abstract":"<p><p>The incidence of light chain deposition disease (LCDD) is relatively low and difficult to diagnose, while cases of PLCDD combined with Sjogren's syndrome are more rare. A case of pulmonary light chain deposit disease combined with Sjogren's syndrome admitted to our department is reported as follows, and the relevant literature is reviewed in order to improve clinicians' understanding of rare diseases and early diagnosis and treatment.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 3","pages":"e70158"},"PeriodicalIF":0.8,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11933749/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143711500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Case of Malignant Airway Obstruction Mimicking Bronchial Asthma.","authors":"Yuka Matsuo, Yuki Takigawa, Ken Sato, Kenichiro Kudo, Hiromi Watanabe, Akiko Sato, Keiichi Fujiwara, Takuo Shibayama","doi":"10.1002/rcr2.70169","DOIUrl":"10.1002/rcr2.70169","url":null,"abstract":"<p><p>Asthma and central airway stenosis are often misdiagnosed due to overlapping clinical features, leading to delayed diagnosis and inappropriate management. A comprehensive diagnostic approach is crucial for accurate differentiation and improving patient outcomes.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 3","pages":"e70169"},"PeriodicalIF":0.8,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11933747/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143711420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Respirology Case ReportsPub Date : 2025-03-25eCollection Date: 2025-03-01DOI: 10.1002/rcr2.70168
Qiang-Zhong Pi, Hu Luo
{"title":"A Rare Case of Plasmacytoma Presenting as Pulmonary Mass.","authors":"Qiang-Zhong Pi, Hu Luo","doi":"10.1002/rcr2.70168","DOIUrl":"10.1002/rcr2.70168","url":null,"abstract":"<p><p>Plasmacytoma can manifest as a solitary pulmonary mass, which can be accurately diagnosed through a combination of Bone scan, serum protein electrophoresis, computed tomography (CT)-guided biopsy and bone marrow biopsy. Notably, this case diagnosed with multiple myeloma (MM) with extramedullary plasmacytoma (EMP) demonstrated an exceptional treatment response to radiotherapy and proteasome inhibitor-based chemotherapy.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 3","pages":"e70168"},"PeriodicalIF":0.8,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11934291/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143711491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pembrolizumab-Induced Anti-Yo-Antibody-Positive Cerebellitis: A Case Report.","authors":"Takafumi Yamano, Toshihide Yokoyama, Tadashi Ishida","doi":"10.1002/rcr2.70160","DOIUrl":"10.1002/rcr2.70160","url":null,"abstract":"<p><p>We report a rare case of pembrolizumab-induced anti-Yo-antibody-positive cerebellitis in a patient with stage IV lung adenocarcinoma. Following two cycles of combination therapy, the patient developed nystagmus and ataxia. Despite tumour regression and normal magnetic resonance imaging (MRI) findings, cerebrospinal fluid analysis revealed lymphocyte-dominant hypercellularity, increased protein, and oligoclonal bands. Immune checkpoint inhibitor (ICI)-related cerebellitis was diagnosed after excluding infectious causes, metastases, and cancerous meningitis coupled with a positive anti-Yo antibody. Methylprednisolone pulse was ineffective, but high-dose intravenous immunoglobulin therapy resolved symptoms. To the best of our knowledge, this is the first case report of ICI-related cerebellitis with anti-Yo-antibody in lung adenocarcinoma. This case highlights the importance of paraneoplastic antibody testing in diagnosing ICI-related encephalitis, especially in cases of normal MRI findings.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 3","pages":"e70160"},"PeriodicalIF":0.8,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11932737/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143701751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Respirology Case ReportsPub Date : 2025-03-24eCollection Date: 2025-03-01DOI: 10.1002/rcr2.70164
Martin Boussuges, Mathilde Cadic, Gaelle Peret, Aurélie Kienlen
{"title":"Two Cases of Tracheal Diverticulum Closure in Bronchoscopy by Argon Plasma Coagulation.","authors":"Martin Boussuges, Mathilde Cadic, Gaelle Peret, Aurélie Kienlen","doi":"10.1002/rcr2.70164","DOIUrl":"10.1002/rcr2.70164","url":null,"abstract":"<p><p>We describe two cases of patients who benefited from closure of symptomatic tracheal diverticulum with argon plasma coagulation by bronchoscopy. When the communication openings between the diverticulum and the trachea are millimetre-sized, the technique is safe and effective. In our experience, two sessions, 1 month apart, are required to achieve complete closure of the diverticulum-related openings.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 3","pages":"e70164"},"PeriodicalIF":0.8,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11932801/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143711505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}