Respirology Case Reports最新文献

Endobronchial Valve Treatment for Persistent Air Leak and Endoscopic Lung Volume Reduction of Native Lung in a Single Lung Transplant Recipient: A Case Report and Literature Review. 单肺移植受者持续性漏气和内镜下肺体积缩小的支气管内瓣膜治疗：1例报告和文献复习。

IF 0.8

Respirology Case Reports Pub Date : 2025-07-30 eCollection Date: 2025-08-01 DOI: 10.1002/rcr2.70305

Joscha Godts, Isabelle Etienne, Christiane Knoop, Dimitri Leduc, Youri Sokolow, Maarten Vander Kuylen, Olivier Taton

{"title":"Endobronchial Valve Treatment for Persistent Air Leak and Endoscopic Lung Volume Reduction of Native Lung in a Single Lung Transplant Recipient: A Case Report and Literature Review.","authors":"Joscha Godts, Isabelle Etienne, Christiane Knoop, Dimitri Leduc, Youri Sokolow, Maarten Vander Kuylen, Olivier Taton","doi":"10.1002/rcr2.70305","DOIUrl":"https://doi.org/10.1002/rcr2.70305","url":null,"abstract":"The use of endobronchial valves (EBV) is a recommended treatment for persistent air leak (PAL) and endoscopic lung volume reduction (ELVR) in selected patients with severe emphysema and absence of collateral ventilation. We report the case of a 52-year-old man who was scheduled for a bilateral sequential lung transplantation, converted to a left single lung transplantation (SLTx) after failure to remove the right lung due to prior thoracic surgery. The post-operative course was complicated by a PAL on the right non-transplanted side, unresponsive to prolonged drainage. Placement of EBV in the right upper and middle lobes, following collateral ventilation evaluation with the Chartis system, resulted in the resolution of the air leak and a concomitant lung volume reduction. Based on a literature review regarding ELVR in single-lung transplanted recipients, we suggest that ELVR with EBV could be a therapeutic option with an acceptable safety profile in this unique population.","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 8","pages":"e70305"},"PeriodicalIF":0.8,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12310813/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144761755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Regorafenib Induced Interstitial Pneumonia in a Patient With Refractory Rectal Cancer. 瑞非尼致难治性直肠癌间质性肺炎1例。

IF 0.8

Respirology Case Reports Pub Date : 2025-07-30 eCollection Date: 2025-08-01 DOI: 10.1002/rcr2.70286

Tomo Tsunoda, Yoshiyuki Oyama, Ryota Miyamoto, Taisuke Ito, Takuro Akashi, Kazuo Tsuchiya, Masaki Ikeda

引用次数: 0

Intractable Pyopneumothorax due to Lemierre's Syndrome Treated With an Endobronchial Watanabe Spigot (EWS). 支气管内Watanabe插管治疗Lemierre综合征所致顽固性气胸。

IF 0.8

Respirology Case Reports Pub Date : 2025-07-30 eCollection Date: 2025-08-01 DOI: 10.1002/rcr2.70302

Mio Sugino, Masao Hashimoto, Sho Morishima, Ayumi Tonsho, Hiroto Hatano, Yutaro Ueki, Mika Iwasaki, Akane Ishida, Go Naka, Shinyu Izumi, Tatsuo Maeyashiki, Satoshi Nagasaka, Masayuki Hojo

{"title":"Intractable Pyopneumothorax due to Lemierre's Syndrome Treated With an Endobronchial Watanabe Spigot (EWS).","authors":"Mio Sugino, Masao Hashimoto, Sho Morishima, Ayumi Tonsho, Hiroto Hatano, Yutaro Ueki, Mika Iwasaki, Akane Ishida, Go Naka, Shinyu Izumi, Tatsuo Maeyashiki, Satoshi Nagasaka, Masayuki Hojo","doi":"10.1002/rcr2.70302","DOIUrl":"https://doi.org/10.1002/rcr2.70302","url":null,"abstract":"Lemierre's syndrome is a rare condition characterised by internal jugular vein thrombophlebitis and bacteremia caused by anaerobic organisms following an oropharyngeal infection. We report the case of a 29-year-old woman who presented with fever, sore throat, dyspnea, and chest pain. Chest computed tomography (CT) revealed lung suppuration, pneumothorax, and thrombosis of the left internal jugular vein, confirming the diagnosis of Lemierre's syndrome. During treatment, she developed pyothorax with bronchopleural fistulas and intractable pneumothorax. Although antibiotics and thoracic drainage controlled the infection, persistent air leakage and incomplete lung expansion remained. Placement of an endobronchial watanabe spigot (EWS) successfully resolved the air leak, allowing the patient to avoid surgery and be discharged. This case highlights the effectiveness of EWS in managing intractable pyopneumothorax secondary to Lemierre's syndrome.","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 8","pages":"e70302"},"PeriodicalIF":0.8,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12310820/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144761756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ABCA3 Surfactant-Related Gene Variant Associated Interstitial Lung Disease in Adults: A Case Series and Review of the Literature. 成人ABCA3表面活性剂相关基因变异与间质性肺疾病：病例系列和文献综述

IF 0.8

Respirology Case Reports Pub Date : 2025-07-30 eCollection Date: 2025-08-01 DOI: 10.1002/rcr2.70304

James Nolan, Jonathan Rodgers, John A Mackintosh

引用次数: 0

Management of Primary Ciliary Dyskinesia in a Kartagener's Syndrome Patient With Total Situs Inversus. 卡塔赫纳综合征完全性位置倒置患者原发性纤毛运动障碍的治疗。

IF 0.8

Respirology Case Reports Pub Date : 2025-07-30 eCollection Date: 2025-08-01 DOI: 10.1002/rcr2.70306

Ivan H Huang, Kenneth N Dang, Saarang Kashyap, Alexander J Sweidan

引用次数: 0

Silicosis Mimicking Lung Malignancy: A Case Series. 模仿肺部恶性肿瘤的矽肺：一个病例系列。

IF 0.8

Respirology Case Reports Pub Date : 2025-07-28 eCollection Date: 2025-07-01 DOI: 10.1002/rcr2.70298

Titia van Duin, Carmen Ambarus, Wouter van Es, Sophie van der Mark, Franz Schramel

引用次数: 0

Primary Pulmonary Leiomyosarcoma: A Case of Prolonged Survival With Radiotherapy and Pazopanib in a 90-Year-Old Female. 原发性肺平滑肌肉瘤：一个90岁女性放疗和帕唑帕尼延长生存的案例。

IF 0.8

Respirology Case Reports Pub Date : 2025-07-28 eCollection Date: 2025-07-01 DOI: 10.1002/rcr2.70301

Sathish Krishnan, Vijaya Sivalingam Ramalingam, Chandrika Patel, Jennifer Heisick

{"title":"Primary Pulmonary Leiomyosarcoma: A Case of Prolonged Survival With Radiotherapy and Pazopanib in a 90-Year-Old Female.","authors":"Sathish Krishnan, Vijaya Sivalingam Ramalingam, Chandrika Patel, Jennifer Heisick","doi":"10.1002/rcr2.70301","DOIUrl":"10.1002/rcr2.70301","url":null,"abstract":"Primary pulmonary leiomyosarcoma is an exceedingly rare malignancy, comprising less than 0.5% of all lung cancers. Due to its rarity, no standardised treatment guidelines exist. Prognosis is especially poor in cases which are deemed unresectable. We describe the case of a 90-year-old woman who presented with progressive dyspnea and cough over 1 month. Chest computed tomography revealed a large right hilar mass extending into the right upper and middle lobes, abutting the mediastinum and pericardium. Histopathological analysis confirmed primary pulmonary leiomyosarcoma. Given her advanced age and comorbidities, she was not a candidate for surgical intervention. Molecular profiling demonstrated PDL1 expression < 1% and no targetable mutations, ruling out the option of immunotherapy. She was managed with palliative radiotherapy followed by pazopanib therapy. Serial imaging demonstrated disease control, with an extended survival of approximately 5 years. Despite a median reported survival of 14 months, our patient achieved prolonged survival, highlighting the importance of an individualised therapeutic approach for elderly patients with rare malignancies.","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 7","pages":"e70301"},"PeriodicalIF":0.8,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12303610/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144733834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Central Airway Recanalisation Using Dual Debulking With Para-Toluenesulfonamide (CLEAR-DUAL-PTS). 使用对甲苯磺酰胺双重减压的中央气道再通（CLEAR-DUAL-PTS）。

IF 0.8

Respirology Case Reports Pub Date : 2025-07-25 eCollection Date: 2025-07-01 DOI: 10.1002/rcr2.70285

Chen Yong Tan, Hui-Xin Tan, Yen Shen Wong, Sumithra Appava, Shoban Raj Vasudayan, Noriah Othman, Swee Wei Leong, Mona Zaria Nasaruddin, Jamalul Azizi Abdul Rahaman

{"title":"Central Airway Recanalisation Using Dual Debulking With Para-Toluenesulfonamide (CLEAR-DUAL-PTS).","authors":"Chen Yong Tan, Hui-Xin Tan, Yen Shen Wong, Sumithra Appava, Shoban Raj Vasudayan, Noriah Othman, Swee Wei Leong, Mona Zaria Nasaruddin, Jamalul Azizi Abdul Rahaman","doi":"10.1002/rcr2.70285","DOIUrl":"10.1002/rcr2.70285","url":null,"abstract":"Pulmonary adenoid cystic carcinoma (PACC) is a rare salivary gland-type malignancy of the tracheobronchial tree, accounting for 0.04%-0.2% of primary lung cancers. It may cause severe malignant airway obstruction (SMAO), necessitating urgent intervention. Surgical resection remains the primary treatment, but inoperability or patient preference may require alternative strategies. We report a case of a 57-year-old non-smoking female with PACC-SMAO who presented with total left lung collapse due to left main bronchus (LMB) involvement. She declined surgery and underwent bronchoscopic dual debulking combining electrocautery snaring with repeated intratumoural para-toluenesulfonamide (PTS) injections. The intervention safely reduced tumour burden, restored airway patency, and significantly improved clinical and radiological outcomes without adverse events. Our case underscores PTS as a promising adjunct therapy for inoperable PACC-SMAO, warranting further investigation into its long-term efficacy and optimal dosing. This innovative approach may significantly redefine palliative care options.","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 7","pages":"e70285"},"PeriodicalIF":0.8,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12290475/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144733832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Case of Complicated Hiatus Hernia Rupture Causing Tension Hydropneumothorax. 复杂性裂孔疝破裂致张力性气胸1例。

IF 0.8

Respirology Case Reports Pub Date : 2025-07-24 eCollection Date: 2025-07-01 DOI: 10.1002/rcr2.70289

Sophie Stewart-Watson, Mohamed Abbas

引用次数: 0

Nonsurgical Pneumoperitoneum: A Rare Thoracoabdominal Complication of Asthma Exacerbation. 非手术气腹：哮喘加重的一种罕见的胸腹并发症。

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Respirology Case Reports Pub Date : 2025-07-24 eCollection Date: 2025-07-01 DOI: 10.1002/rcr2.70294

Takuya Nagahara, Kazuhiko Iwasaki, Saya Tsukida, Akihito Okazaki

引用次数: 0