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Direct Tumour Seeding Following Medical Thoracoscopy in EGFR-Mutated Lung Adenocarcinoma: A Case Report.
IF 0.8
Respirology Case Reports Pub Date : 2025-02-20 eCollection Date: 2025-02-01 DOI: 10.1002/rcr2.70130
Kazuhiko Iwasaki, Akihito Okazaki, Yasuhiko Matsuda
{"title":"Direct Tumour Seeding Following Medical Thoracoscopy in EGFR-Mutated Lung Adenocarcinoma: A Case Report.","authors":"Kazuhiko Iwasaki, Akihito Okazaki, Yasuhiko Matsuda","doi":"10.1002/rcr2.70130","DOIUrl":"10.1002/rcr2.70130","url":null,"abstract":"<p><p>This case demonstrates the risk of tumour seeding after medical thoracoscopy for EGFR-mutated lung adenocarcinoma. Clinicians should balance the diagnostic benefits against potential complications, closely monitor intervention sites, and consider early local control strategies such as radiation therapy to effectively manage procedure-related risks.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 2","pages":"e70130"},"PeriodicalIF":0.8,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11842089/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143469384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Low Grade Pulmonary Spindle Cell Neoplasm in a 30-Year-Old Asymptomatic Female: A Diagnostic Dilemma: A Case Report.
IF 0.8
Respirology Case Reports Pub Date : 2025-02-19 eCollection Date: 2025-02-01 DOI: 10.1002/rcr2.70110
Jerica Eliesa Juarez, Albert Lim Rafanan, Matthew Go Yap
{"title":"Low Grade Pulmonary Spindle Cell Neoplasm in a 30-Year-Old Asymptomatic Female: A Diagnostic Dilemma: A Case Report.","authors":"Jerica Eliesa Juarez, Albert Lim Rafanan, Matthew Go Yap","doi":"10.1002/rcr2.70110","DOIUrl":"10.1002/rcr2.70110","url":null,"abstract":"<p><p>Pulmonary spindle cell carcinoma is a highly malignant rare variant of sarcomatoid lung carcinomas. This is a case of an asymptomatic 30-year-old Filipino female with an incidental finding of pulmonary nodules on chest x-ray. Patient was diagnosed with Wilms tumor at the age of 2, S/P nephrectomy with no documented recurrence thereafter. Computed tomography (CT) chest scan showed non-calcified fat density nodules in her right upper, middle and lower lobe. A positron emission tomography (PET) CT scan identified lobulated pulmonary mass with low-grade metabolic activity. Video Assisted Thoracic Surgery with wedge resection of the right lung was done. Final biopsy noted fibroepithelial lesions in the parenchyma which composed of bland spindle cells. ER, SMA, desmin, and caldesmon were diffusely positive consistent with a low-grade spindle cell neoplasm. Genetic testing showed CTNNB1 S45F subclonal mutations. No chemotherapy nor radiotherapy were done. Repeat PET CT of the whole body showed a decrease in size of the mass.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 2","pages":"e70110"},"PeriodicalIF":0.8,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11840237/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143469452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Encysted Pneumomediastinum With Septations Following Talc Pleurodesis for a Secondary Spontaneous Pneumothorax.
IF 0.8
Respirology Case Reports Pub Date : 2025-02-19 eCollection Date: 2025-02-01 DOI: 10.1002/rcr2.70123
Sugeesha Wickramasinghe, Sanjeewa Hettiarachchi, Susan Kearney, Sharada Gudur
{"title":"Encysted Pneumomediastinum With Septations Following Talc Pleurodesis for a Secondary Spontaneous Pneumothorax.","authors":"Sugeesha Wickramasinghe, Sanjeewa Hettiarachchi, Susan Kearney, Sharada Gudur","doi":"10.1002/rcr2.70123","DOIUrl":"https://doi.org/10.1002/rcr2.70123","url":null,"abstract":"<p><p>Encysted pneumomediastinum with septations is an extremely rare phenomenon. Talc treatment can leak through fistulous tracts to the mediastinum, walling off air collection, which is not commonly described in the literature. Clinicians should be aware of this complication, as these can be easily missed, causing complications.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 2","pages":"e70123"},"PeriodicalIF":0.8,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11836527/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143460095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pulmonary Enteric Adenocarcinoma in a Super-Elderly Patient: A Case Report and Literature Review.
IF 0.8
Respirology Case Reports Pub Date : 2025-02-19 eCollection Date: 2025-02-01 DOI: 10.1002/rcr2.70127
Akira Shimamoto, Natsumi Kojo, Haruko Saiki, Akinobu Hayashi, Motoshi Takao
{"title":"Pulmonary Enteric Adenocarcinoma in a Super-Elderly Patient: A Case Report and Literature Review.","authors":"Akira Shimamoto, Natsumi Kojo, Haruko Saiki, Akinobu Hayashi, Motoshi Takao","doi":"10.1002/rcr2.70127","DOIUrl":"10.1002/rcr2.70127","url":null,"abstract":"<p><p>Pulmonary enteric adenocarcinoma (PEAC) is an extremely rare subtype of non-small cell lung cancer, characterised by histopathological features that resemble colorectal adenocarcinoma. Here, we report a case of PEAC in an 85-year-old male who presented with a pulmonary nodule initially identified at the age of 76. Initial PET-CT (maximum standardised uptake value [SUVmax] = 2.8) was inconclusive, leading to strict follow-up. Over 9 years, the nodule enlarged significantly (3.2 cm, SUVmax = 8.4). A transbronchial biopsy confirmed adenocarcinoma, and the patient underwent successfully video-assisted thoracoscopic surgery with lymph node dissection. The histopathological analysis revealed CK7 and CK20 positivity, focal CDX2 positivity, and TTF-1 negativity, confirming PEAC. Despite advanced age, the patient tolerated surgery well without adjuvant therapy. At the one-year postoperative follow-up, he remained disease-free. This case emphasises the diagnostic utility of immunohistochemistry and the feasibility of surgical management, even in super-elderly patients with PEAC.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 2","pages":"e70127"},"PeriodicalIF":0.8,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11839735/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143469543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lifesaving Sign in Non-Contrast CT Scan in the Case of Pulmonary Thromboembolism.
IF 0.8
Respirology Case Reports Pub Date : 2025-02-19 eCollection Date: 2025-02-01 DOI: 10.1002/rcr2.70126
Elaheh Hajinoormohammadi, Hesam Amini, Sara Malekshahian, Sara Soltanmohammadi
{"title":"Lifesaving Sign in Non-Contrast CT Scan in the Case of Pulmonary Thromboembolism.","authors":"Elaheh Hajinoormohammadi, Hesam Amini, Sara Malekshahian, Sara Soltanmohammadi","doi":"10.1002/rcr2.70126","DOIUrl":"10.1002/rcr2.70126","url":null,"abstract":"<p><p>The two most important signs of pulmonary embolism (PE) in a non-contrast CT scan include wedge-shaped sub-pleural opacity surrounded by an air-space consolidation, along with a ground-glass opacity in the center consistent with pulmonary infarction, also known as the reverse halo sign and the hyperdense lumen sign.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 2","pages":"e70126"},"PeriodicalIF":0.8,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11837026/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143460068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Endobronchial Leiomyoma Presenting as Post-Obstructive Pneumonia.
IF 0.8
Respirology Case Reports Pub Date : 2025-02-18 eCollection Date: 2025-02-01 DOI: 10.1002/rcr2.70124
Boon Hau Ng, Hsueh Jing Low, Nik Nuratiqah Nik Abeed, Nor Safiqah Sharil, Rose Azzlinda Osman, Maalini Krishnasamy, Andrea Yu-Lin Ban, Jamalul Azizi Abdul Rahaman
{"title":"Endobronchial Leiomyoma Presenting as Post-Obstructive Pneumonia.","authors":"Boon Hau Ng, Hsueh Jing Low, Nik Nuratiqah Nik Abeed, Nor Safiqah Sharil, Rose Azzlinda Osman, Maalini Krishnasamy, Andrea Yu-Lin Ban, Jamalul Azizi Abdul Rahaman","doi":"10.1002/rcr2.70124","DOIUrl":"10.1002/rcr2.70124","url":null,"abstract":"<p><p>Endobronchial leiomyoma is a rare airway tumour. We report the case of a 30-year-old female non-smoker who presented with persistent fever and cough, ultimately diagnosed with post-obstructive pneumonia secondary to an endobronchial leiomyoma. The patient underwent a successful endobronchial cryo-resection with the resolution of symptoms. This case highlights the importance of considering rare causes of non-resolving pneumonia and the role of a minimally invasive approach in the management of endobronchial leiomyoma.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 2","pages":"e70124"},"PeriodicalIF":0.8,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11835759/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143460101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lung Mass With Crazy-Paving: An Unusual Initial Presentation of Acute Myeloid Leukaemia.
IF 0.8
Respirology Case Reports Pub Date : 2025-02-18 eCollection Date: 2025-02-01 DOI: 10.1002/rcr2.70128
Fui Bee Woo, Han Loong Tan, Raymund Dass Maria Dass, Shobhana Sivandan
{"title":"Lung Mass With Crazy-Paving: An Unusual Initial Presentation of Acute Myeloid Leukaemia.","authors":"Fui Bee Woo, Han Loong Tan, Raymund Dass Maria Dass, Shobhana Sivandan","doi":"10.1002/rcr2.70128","DOIUrl":"10.1002/rcr2.70128","url":null,"abstract":"<p><p>Acute myeloid leukaemia is known to present non-specifically and more commonly with B symptoms. We report an interesting presentation of acute myeloid leukaemia as a lung mass which initially raised clinical suspicion of primary lung cancer. A gentleman in his 50s who is an active smoker presented with chronic cough, lethargy, and giddiness for 2 months. Physical examination revealed pallor, cervical lymphadenopathy, and bronchial breathing over the right middle zone on auscultation. CT thorax showed a spiculated solid mass with a crazy-paving pattern, suggestive of lung cancer. However, blood workup showed pancytopenia with a full blood picture showing 60% blast cells. Subsequent bone marrow examination confirmed the diagnosis of AML. The patient received 2-weekly venetoclax-based chemotherapy. Serial follow-up CT showed resolution of lung changes and the patient remained in remission.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 2","pages":"e70128"},"PeriodicalIF":0.8,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11835944/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143460075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Capricious Radiographic Presentations of Pulmonary Benign Metastasizing Leiomyoma Raise Diagnostic Challenges.
IF 0.8
Respirology Case Reports Pub Date : 2025-02-18 eCollection Date: 2025-02-01 DOI: 10.1002/rcr2.70125
Chao-Hsin Huang, Chieh-Ni Kao, Kun-Bow Tsai, Ping-Ruey Chou, Shah-Hwa Chou, Yu-Wei Liu
{"title":"Capricious Radiographic Presentations of Pulmonary Benign Metastasizing Leiomyoma Raise Diagnostic Challenges.","authors":"Chao-Hsin Huang, Chieh-Ni Kao, Kun-Bow Tsai, Ping-Ruey Chou, Shah-Hwa Chou, Yu-Wei Liu","doi":"10.1002/rcr2.70125","DOIUrl":"10.1002/rcr2.70125","url":null,"abstract":"<p><p>Pulmonary benign metastasizing leiomyoma (PBML) cases are often asymptomatic and exhibit various imaging patterns, posing diagnostic challenges and frequently mimicking malignancies or other atypical histologies. Herein, we present three cases of PBML in women, each with distinct radiographic features, all managed through surgical interventions. These cases underscore the importance of early detection for prompt diagnosis and treatment. Furthermore, they highlight the need to consider PBML as a differential diagnosis in women with a history of uterine leiomyoma presenting with indeterminate lung masses and diverse radiographic findings.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 2","pages":"e70125"},"PeriodicalIF":0.8,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11835955/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143460091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Endobronchial Aspergilloma.
IF 0.8
Respirology Case Reports Pub Date : 2025-02-18 eCollection Date: 2025-02-01 DOI: 10.1002/rcr2.70121
So Shimamura, Nozomu Takahashi, Kenta Homma, Tsukasa Satoh, Satoshi Furuya, Hiroki Ohkoshi, Yuki Hoshino, Yoshinori Uchida, Masafumi Saiki, Shinnosuke Ikemura, Kenzo Soejima
{"title":"Endobronchial Aspergilloma.","authors":"So Shimamura, Nozomu Takahashi, Kenta Homma, Tsukasa Satoh, Satoshi Furuya, Hiroki Ohkoshi, Yuki Hoshino, Yoshinori Uchida, Masafumi Saiki, Shinnosuke Ikemura, Kenzo Soejima","doi":"10.1002/rcr2.70121","DOIUrl":"10.1002/rcr2.70121","url":null,"abstract":"<p><p>Bronchial aspergilloma, an uncommon subtype of pulmonary aspergilloma, likely developed in the main bronchus due to airflow stagnation and dryness following lobectomy. Detailed imaging and bronchoscopy provided valuable diagnostic insights, underscoring the importance of considering fungal infections in surgically altered airways.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 2","pages":"e70121"},"PeriodicalIF":0.8,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11835757/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143460097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
IgG4 Related Disease Presenting With Eosinophilic Pleural Effusion.
IF 0.8
Respirology Case Reports Pub Date : 2025-02-15 eCollection Date: 2025-02-01 DOI: 10.1002/rcr2.70111
Ancy Elsa Thomas, Balamugesh Thangakunam, Thomas Kodiatte, Devasahayam Jesudas Christopher
{"title":"IgG4 Related Disease Presenting With Eosinophilic Pleural Effusion.","authors":"Ancy Elsa Thomas, Balamugesh Thangakunam, Thomas Kodiatte, Devasahayam Jesudas Christopher","doi":"10.1002/rcr2.70111","DOIUrl":"10.1002/rcr2.70111","url":null,"abstract":"<p><p>A 56-year-old man presented with right-sided pleuritic chest pain and intermittent cough for 4 months, with a background history of well-controlled asthma and allergic rhinitis. Chest radiographs revealed right-sided pleural effusion, the fluid chemistry showed an exudate effusion with negative cytology and abundant eosinophils. Thoracoscopic pleural biopsy showed moderate lymphoplasmacytic chronic inflammation. Immunohistochemistry showed IgG4 staining up to 90 plasma cells/hpf (> 10% diagnostic), and the IgG4: IgG ratio was 40% (> 40% diagnostic), confirming the diagnosis of IgG4-related disease (IgG4-RD). Elevated serum IgG4 level (300 mg/dL; normal range: 3-201 mg/dL), further supported the diagnosis. While eosinophilic pleural effusion (EPE) accounts for 5%-16% of all exudative pleural effusions, IgG4-related pleural disease is an extremely rare cause of EPE.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 2","pages":"e70111"},"PeriodicalIF":0.8,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11829249/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143434144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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