Respirology Case Reports最新文献_第2页

Endoscopic Ultrasound With Bronchoscope-Guided Fine-Needle Aspiration (EUS-B-FNA) in a six-Month-Old Infant: A Case Based Review of Literature. 内镜超声与支气管镜引导下细针抽吸（EUS-B-FNA）在6个月婴儿：一个病例为基础的文献回顾。

IF 0.7

Respirology Case Reports Pub Date : 2026-09-30 eCollection Date: 2026-10-01 DOI: 10.1002/rcr2.70773

Venkata Nagarjuna Maturu, Srinivas Jakka, Meghna Rai, Rinoosha Rachel

{"title":"Endoscopic Ultrasound With Bronchoscope-Guided Fine-Needle Aspiration (EUS-B-FNA) in a six-Month-Old Infant: A Case Based Review of Literature.","authors":"Venkata Nagarjuna Maturu, Srinivas Jakka, Meghna Rai, Rinoosha Rachel","doi":"10.1002/rcr2.70773","DOIUrl":"https://doi.org/10.1002/rcr2.70773","url":null,"abstract":"Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is an established, minimally invasive modality for evaluating mediastinal pathologies in adults. However, its application in infants remains extremely limited because of airway size constraints and procedural safety concerns. We report the case of a 6-month-old infant presenting with recurrent lower respiratory tract infections and a posterior mediastinal lesion causing bronchial compression. Contrast-enhanced computed tomography demonstrated a well-defined cystic lesion in the right posterior mediastinum, with differential diagnoses including bronchogenic cyst, duplication cyst and necrotic lymphadenopathy. Given diagnostic uncertainty and the risks of primary surgical intervention, EUS-B-FNA was performed via transoesophageal approach under general anaesthesia. Cytological analysis revealed cyst macrophages and acellular mucoid debris, confirming a bronchogenic cyst. The patient subsequently underwent definitive surgical excision and remained symptom-free on follow-up. This case represents the youngest reported infant to undergo successful mediastinal sampling using EUS-B-FNA and highlights the feasibility, safety and diagnostic utility of the transoesophageal bronchoscopic ultrasound approach in very young children when performed in experienced centres.","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"14 10","pages":"e70773"},"PeriodicalIF":0.7,"publicationDate":"2026-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13625811/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149116172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unilateral Pulmonary Artery Lesion in an Immunocompromised Patient. 免疫功能低下患者单侧肺动脉病变。

IF 0.7

Respirology Case Reports Pub Date : 2026-09-30 eCollection Date: 2026-10-01 DOI: 10.1002/rcr2.70778

Seunghoon Lee, Kyung Soo Lee, Dong Young Jeong, Boram Lee, Junghee Lee, Dong Seop Jeong, Sung-A Chang, Sun Hye Shin

{"title":"Unilateral Pulmonary Artery Lesion in an Immunocompromised Patient.","authors":"Seunghoon Lee, Kyung Soo Lee, Dong Young Jeong, Boram Lee, Junghee Lee, Dong Seop Jeong, Sung-A Chang, Sun Hye Shin","doi":"10.1002/rcr2.70778","DOIUrl":"https://doi.org/10.1002/rcr2.70778","url":null,"abstract":"We report a 62-year-old man with myelodysplastic syndrome on immunosuppressive therapy who presented with right lung consolidation and neutropenia. Despite broad antimicrobial therapy for presumed pneumonia, negative microbiologic studies including bronchoalveolar lavage, and a nondiagnostic transbronchial biopsy, serial computed tomography (CT) scans showed progressive right-sided consolidation, pleural effusion and CT signs of pulmonary hypertension. A routine contrast-enhanced CT revealed a filling defect in the right pulmonary artery (PA). Dedicated CT pulmonary angiography confirmed persistent unilateral PA obstruction; together with pulmonary hypertension and a lack of improvement despite anticoagulation, this raised concern for chronic thromboembolic disease and PA malignancy. Fluorodeoxyglucose positron emission tomography (FDG PET) CT demonstrated mildly heterogeneous FDG uptake (SUVmax 2.9) favouring thrombus, and endobronchial ultrasound-guided transbronchial needle aspiration yielded necrotic thrombotic material. Pulmonary endarterectomy, performed after interval clinical worsening, confirmed a chronic organizing septic thrombus. Weeks later, haemorrhagic infarction caused massive haemoptysis requiring wedge resection of the lung. This case highlights a rare septic thrombus in a unilateral PA leading to pulmonary infarction in an immunocompromised host.","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"14 10","pages":"e70778"},"PeriodicalIF":0.7,"publicationDate":"2026-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13626769/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149116310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pulmonary Vein Stenosis Following Radiofrequency Catheter Ablation Presenting With Massive Pleural Effusion: A Case Report. 射频导管消融后肺静脉狭窄伴大量胸腔积液1例报告。

IF 0.7

Respirology Case Reports Pub Date : 2026-09-29 eCollection Date: 2026-10-01 DOI: 10.1002/rcr2.70770

Yasuhiko Nikaido, Kei Yamasaki, Tatsuya Shingu, Yuki Hayakawa, Yuto Iwanaga, Yosuke Sasahara, Kazuhiro Yatera

引用次数: 0

Pulmonary AL Amyloidosis as a Cause of Interstitial Lung Disease Diagnosed With Transbronchial Lung Biopsy. 肺AL淀粉样变是经支气管肺活检诊断的间质性肺疾病的病因。

IF 0.7

Respirology Case Reports Pub Date : 2026-09-22 eCollection Date: 2026-09-01 DOI: 10.1002/rcr2.70769

Kai Wen Hwang, Ju Ee Seet, Michelle Poon, Kay Choong See

引用次数: 0

Thoracic and Umbilical Endometriosis Concurrently Presenting During Secondary Subfertility Evaluation. 继发性不孕评估期间同时出现的胸脐子宫内膜异位症。

IF 0.7

Respirology Case Reports Pub Date : 2026-09-22 eCollection Date: 2026-09-01 DOI: 10.1002/rcr2.70760

Nabeela Khan, Saadia Ashraf, Hamza Khan Khattak, Afra Khan, Kamil Ahmad Kamil

{"title":"Thoracic and Umbilical Endometriosis Concurrently Presenting During Secondary Subfertility Evaluation.","authors":"Nabeela Khan, Saadia Ashraf, Hamza Khan Khattak, Afra Khan, Kamil Ahmad Kamil","doi":"10.1002/rcr2.70760","DOIUrl":"10.1002/rcr2.70760","url":null,"abstract":"Thoracic endometriosis is a rare manifestation of extra pelvic endometriosis and it is often missed because of its variable clinical presentation. A 33-year-old woman undergoing evaluation for secondary subfertility presented with a three-year history of cyclical periumbilical pain, swelling and occasional catamenial bleeding. Contrast-enhanced CT (CECT) abdomen and pelvis demonstrated an umbilical soft tissue nodule consistent with umbilical endometriosis which was histologically confirmed. Incidentally this CECT also revealed a right-sided pleural effusion with a pleural-based nodule despite absence of respiratory symptoms. Thoracentesis yielded haemorrhagic exudative fluid, while thoracoscopy showed multiple nodules and haemorrhagic cysts on parietal and visceral pleura. Histopathology and immunohistochemistry confirmed pleural endometriosis. The patient subsequently developed a pneumothorax requiring chest tube repositioning and was treated with gonadotropin-releasing hormone (GnRH) analogue therapy, resulting in complete symptomatic and radiological resolution at follow-up. Hormonal therapy was later discontinued to pursue conception; however, recurrence of pleural effusion occurred, necessitating continuation of the medication. This case highlights the silent and multifocal nature of extra-pelvic endometriosis.","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"14 9","pages":"e70760"},"PeriodicalIF":0.7,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13597159/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149026370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of Severe COVID-19 on Interstitial Lung Disease in Autoimmune Systemic Diseases. 重症COVID-19对自身免疫性全身性疾病间质性肺疾病的影响

IF 0.7

Respirology Case Reports Pub Date : 2026-09-22 eCollection Date: 2026-09-01 DOI: 10.1002/rcr2.70472

Clodoveo Ferri, Marco de Pinto, Giuseppe Murdaca, Giacomo De Luca, Davide Mohammad Reza Beigi, Virginia Caira, Roberta Foti, Andrea Cito, Caterina Naclerio, Jessica Maria Elisa Luppino, Amelia Spinella, Martina Orlandi, Veronica Batani, Federica Lumetti, Francesco Prampolini, Giuseppe Varcasia, Rosario Foti, Valeria Riccieri, Florenzo Iannone, Alessandro Antonelli, Dilia Giuggioli

{"title":"Impact of Severe COVID-19 on Interstitial Lung Disease in Autoimmune Systemic Diseases.","authors":"Clodoveo Ferri, Marco de Pinto, Giuseppe Murdaca, Giacomo De Luca, Davide Mohammad Reza Beigi, Virginia Caira, Roberta Foti, Andrea Cito, Caterina Naclerio, Jessica Maria Elisa Luppino, Amelia Spinella, Martina Orlandi, Veronica Batani, Federica Lumetti, Francesco Prampolini, Giuseppe Varcasia, Rosario Foti, Valeria Riccieri, Florenzo Iannone, Alessandro Antonelli, Dilia Giuggioli","doi":"10.1002/rcr2.70472","DOIUrl":"10.1002/rcr2.70472","url":null,"abstract":"The objective of this study was to assess the impact of severe COVID-19 pneumonia on the course of interstitial lung disease (ILD) in autoimmune systemic diseases (ASD). We conducted a multicentre case series of 27 ASD patients (20 systemic sclerosis, 4 rheumatoid arthritis, 1 interstitial pneumonia with autoimmune features, 1 dermatomyositis, 1 eosinophilic granulomatosis with polyangiitis) hospitalised for severe COVID-19. Clinical data, pulmonary function tests and HRCT before and after infection were analysed. Four patients died during acute COVID-19. Among the 23 survivors, 10 developed new symptomatic ILD and 13 showed worsening of pre-existing ILD. Six exhibited significant HRCT progression, including NSIP-to-UIP transition; one developed lung adenocarcinoma. Despite treatment, five more patients died during follow-up from progressive ILD. Overall mortality approached one-third, with systemic sclerosis most affected. Severe COVID-19 may trigger or accelerate ASD-related ILD. The observed NSIP-to-UIP shift highlights a multistep process potentially driven by SARS-CoV-2, underscoring the need for close ILD monitoring in ASD patients.","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"14 9","pages":"e70472"},"PeriodicalIF":0.7,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13597466/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149041253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sequential Laser Photoresection and Cryotherapy for Very Late Recurrent Subglottic Atypical Carcinoid: A Case Report. 顺序激光光切除和冷冻治疗晚期复发的声门下不典型类癌1例。

IF 0.7

Respirology Case Reports Pub Date : 2026-09-22 eCollection Date: 2026-09-01 DOI: 10.1002/rcr2.70771

Meridiana Dodaj, Lorenzo Carriera, Pier-Valerio Mari, Stefano Baglioni, Roberto Lipsi

{"title":"Sequential Laser Photoresection and Cryotherapy for Very Late Recurrent Subglottic Atypical Carcinoid: A Case Report.","authors":"Meridiana Dodaj, Lorenzo Carriera, Pier-Valerio Mari, Stefano Baglioni, Roberto Lipsi","doi":"10.1002/rcr2.70771","DOIUrl":"10.1002/rcr2.70771","url":null,"abstract":"Atypical pulmonary carcinoids may recur many years after initial treatment, but very late central-airway recurrence is uncommon and its optimal endoscopic management is uncertain. We report a 67-year-old man with metastatic atypical pulmonary carcinoid who developed recurrent subglottic disease almost 20 years after pulmonary resection. Following mild haemoptysis and inspiratory dyspnoea, bronchoscopy showed progression of a known subglottic lesion causing approximately 80% tracheal obstruction. Laser photoresection achieved rapid debulking, haemostasis and marked airway recanalization. Residual endoluminal disease was treated 5 months later with cryotherapy, resulting in complete endoscopic recanalization. No major complications occurred, symptoms resolved, and follow-up bronchoscopy at 3 months showed sustained airway patency without significant residual obstruction. This case illustrates the feasibility of a sequential multimodal bronchoscopic approach combining immediate thermal debulking with non-thermal treatment of residual disease.","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"14 9","pages":"e70771"},"PeriodicalIF":0.7,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13597158/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149026344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transbronchial Access of Solitary Pulmonary Nodules Without Bronchus Sign Using a Novel Puncture Dilatation Catheter: Initial Feasibility Experience. 新型穿刺扩张导管经支气管进入无支气管征象的孤立性肺结节：初步可行性经验。

IF 0.7

Respirology Case Reports Pub Date : 2026-09-22 eCollection Date: 2026-09-01 DOI: 10.1002/rcr2.70746

Sze Shyang Kho, Chan Sin Chai

{"title":"Transbronchial Access of Solitary Pulmonary Nodules Without Bronchus Sign Using a Novel Puncture Dilatation Catheter: Initial Feasibility Experience.","authors":"Sze Shyang Kho, Chan Sin Chai","doi":"10.1002/rcr2.70746","DOIUrl":"10.1002/rcr2.70746","url":null,"abstract":"Radial endobronchial ultrasound (rEBUS) guided biopsy is highly effective for solitary pulmonary nodules exhibiting a bronchus sign. While ancillary techniques like cryobiopsy improve yields for lesions adjacent to the airway, nodules situated deeper within the lung parenchyma or behind stenotic, fibrotic airways often require specialised transbronchial access. Conventional transbronchial access tools are frequently limited by their large calibre, requiring bronchoscopes with wide working channels and complex, multi-step deployment that increases procedural complexity. We report our initial clinical experience with a novel, single-use transbronchial puncture dilatation catheter. This device features a flexible sheath with a tapered distal end and an integrated needle stylet, specifically designed to simplify bronchial wall penetration and parenchymal tunnelling via a thin bronchoscope with 2.0 mm working channel. We present two cases: a solitary pulmonary nodule lacking a bronchus sign and a second case involving a fibrotic, stenotic airway that precluded standard rEBUS probe insertion. In both instances, the novel catheter facilitated successful 'off-road' navigation, allowing for rEBUS verification and definitive sampling with cryoprobe and forceps. Both procedures were technically successful, yielding metastatic adenocarcinoma and caseating granulomatous inflammation, respectively. This case series explores the early clinical utility of this simplified transbronchial access tool and discusses its current limitations.","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"14 9","pages":"e70746"},"PeriodicalIF":0.7,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13597468/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149041265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Life-Saving Cryoextraction for Acute Severe Respiratory Failure Caused by Cheese-Filled Fish Cake Aspiration: A Case Report. 冷冻抽吸治疗因奶酪鱼饼吸入引起的急性严重呼吸衰竭1例。

IF 0.7

Respirology Case Reports Pub Date : 2026-09-17 eCollection Date: 2026-09-01 DOI: 10.1002/rcr2.70768

Mayu Goda, Yuki Takigawa, Ken Sato, Hitoshi Hara, Tomoya Osedo, Yuto Sasano, Toki Kitano, Keisuke Shiraha, Suzuka Matsuoka, Jun Nishimura, Hiromi Watanabe, Kenichiro Kudo, Keiichi Fujiwara

引用次数: 0

Pulmonary Mycobacterium fortuitum Infection Associated With Achalasia Treated With Peroral Endoscopic Myotomy Alone: A Case Report. 经口内窥镜下肌切开术治疗肺偶发分枝杆菌感染伴贲门失弛缓症1例。

IF 0.7

Respirology Case Reports Pub Date : 2026-09-17 eCollection Date: 2026-09-01 DOI: 10.1002/rcr2.70718

Hidetaka Masuda, Ryo Torii, Kei Yamasaki, Tatsuya Shingu, Ryosuke Hata, Kazuhiro Yatera

引用次数: 0