Respirology Case Reports最新文献_第2页

Personalised CFTR Modulator Treatment Initiation and Monitoring in CF-Related Liver Disease: When Less Is More. cf相关肝病个体化CFTR调节剂治疗的启动和监测：少即是多

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Respirology Case Reports Pub Date : 2025-03-24 eCollection Date: 2025-03-01 DOI: 10.1002/rcr2.70146

Sona Vekaria, Grace Kavanagh, Siobhain Mulrennan

引用次数: 0

Allergic Bronchopulmonary Mycosis Caused by Schizophyllum commune Successfully Treated With Mepolizumab. Mepolizumab成功治疗裂叶菌引起的过敏性支气管肺真菌病。

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Respirology Case Reports Pub Date : 2025-03-20 eCollection Date: 2025-03-01 DOI: 10.1002/rcr2.70161

Mitsuki Kakiuchi, Yuki Takigawa, Ken Sato, Hiromi Watanabe, Kenichiro Kudo, Akiko Sato, Keiichi Fujiwara, Takuo Shibayama

{"title":"Allergic Bronchopulmonary Mycosis Caused by Schizophyllum commune Successfully Treated With Mepolizumab.","authors":"Mitsuki Kakiuchi, Yuki Takigawa, Ken Sato, Hiromi Watanabe, Kenichiro Kudo, Akiko Sato, Keiichi Fujiwara, Takuo Shibayama","doi":"10.1002/rcr2.70161","DOIUrl":"10.1002/rcr2.70161","url":null,"abstract":"Allergic bronchopulmonary mycosis (ABPM) is a complication of bronchial asthma (BA) and can lead to lung damage and respiratory failure. The standard treatment for ABPM is steroid therapy. Nonetheless, this treatment increases the risk of infections and osteoporosis. Alternative therapies include immunomodulatory biologics and mucus plug removal by bronchoscopy. This report describes a case of a 70-year-old man diagnosed with BA in 2014 and treated with inhaled corticosteroids/long-acting beta-agonists, which were later discontinued for unknown reasons. He was presented to our department with a BA attack, including wheezing and desaturation. Computed tomography and laboratory examinations suggested ABPM; the patient underwent mucus plug removal. The final diagnosis was ABPM, and steroids and itraconazole were initiated. However, BA symptoms did not improve, and the mucus plug and desaturation persisted. Mepolizumab (100 mg/month) subcutaneously cleared the plug and improved BA. This case demonstrates that mepolizumab can treat patients with ABPM and refractory BA.","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 3","pages":"e70161"},"PeriodicalIF":0.8,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11925694/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143693934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Primary Ciliary Dyskinesia Complicated by Stroke in an Elderly Male: A Case Report. 老年男性原发性纤毛运动障碍并发脑卒中1例。

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Respirology Case Reports Pub Date : 2025-03-20 eCollection Date: 2025-03-01 DOI: 10.1002/rcr2.70163

Ali Gohar, Bilal Ahmed, Asim Ali, Maryam Ilyas, Momina Masroor, Ayesha Ayman, Masab Ali, Muhammad Husnain Ahmad

{"title":"Primary Ciliary Dyskinesia Complicated by Stroke in an Elderly Male: A Case Report.","authors":"Ali Gohar, Bilal Ahmed, Asim Ali, Maryam Ilyas, Momina Masroor, Ayesha Ayman, Masab Ali, Muhammad Husnain Ahmad","doi":"10.1002/rcr2.70163","DOIUrl":"10.1002/rcr2.70163","url":null,"abstract":"Kartagener syndrome (KS) is an uncommon hereditary disorder, featuring situs inversus, chronic sinusitis, and bronchiectasis. Our case report presents a 60-year-old Asian male with KS who was incidentally diagnosed with KS upon presenting with an ischemic cerebrovascular accident (CVA). The patient had a longstanding history of poorly controlled type 2 diabetes mellitus and hypertension, presenting with acute right-sided weakness and speech impairment. His history of recurrent respiratory infections and infertility, combined with family findings of dextrocardia and male infertility, suggested KS. On physical examination, the patient exhibited signs of dextrocardia. Imaging confirmed situs inversus and dextrocardia, while neurological evaluation revealed an embolic stroke in the left middle cerebral artery territory. Certain cardiovascular anomalies in KS may affect stroke risk; however, their co-occurrence in the patient appears to be coincidental, given the patient's baseline risk for stroke. A high-resolution chest CT demonstrated bronchiectasis and carotid Doppler ultrasound identified atherosclerotic plaques, likely contributing to the stroke. This case highlights the need for heightened awareness of neurological events, such as stroke, in patients with KS. Cardiovascular risk factors, compounded by the complexity of the syndrome, require prompt evaluation and multidisciplinary care to prevent severe complications.","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 3","pages":"e70163"},"PeriodicalIF":0.8,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11926249/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143693936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bronchopleural Fistula Following COVID-19 and Necrotizing Pneumonia in Childhood: Treatment With Intrapleural Vacuum-Assisted Closure Therapy. 儿童COVID-19和坏死性肺炎后支气管胸膜瘘：胸膜内真空辅助封闭治疗

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Respirology Case Reports Pub Date : 2025-03-20 eCollection Date: 2025-03-01 DOI: 10.1002/rcr2.70134

Jose Carlos Fraga, Felipe Colombo Holanda, Natalia Zanini Silva, Maria Fernanda Oliveira, Paola Santis Isolan, Elenara Fonseca Procianoy

{"title":"Bronchopleural Fistula Following COVID-19 and Necrotizing Pneumonia in Childhood: Treatment With Intrapleural Vacuum-Assisted Closure Therapy.","authors":"Jose Carlos Fraga, Felipe Colombo Holanda, Natalia Zanini Silva, Maria Fernanda Oliveira, Paola Santis Isolan, Elenara Fonseca Procianoy","doi":"10.1002/rcr2.70134","DOIUrl":"10.1002/rcr2.70134","url":null,"abstract":"Bronchopleural fistula is an abnormal communication between the bronchial tree and the pleural space. Necrotizing pneumonia is a catastrophic infection of the lungs characterised by necrosis of the interstitial tissue. Although rarely reported, it has been described as a complication of COVID-19. The usual treatment for bronchopleural fistula involves endoscopic or surgical procedures. We present the case of a 5-year-old girl admitted with necrotizing pneumonia and difficult-to-control bronchopleural fistula, with a report of flu-like illness and a positive PCR test for COVID-19 2 months earlier. Over 38 days, several procedures were performed, including left-side tube drainage, thoracotomy, segmental resection, open window thoracotomy, and finally vacuum-assisted closure (VAC) therapy. Twenty days after the start of VAC therapy, complete closure of the bronchopleural fistula was achieved. At 26 months of follow-up, the child remained asymptomatic, with radiological examinations showing pulmonary expansion and absence of intrapleural air.","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 3","pages":"e70134"},"PeriodicalIF":0.8,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11925471/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143671408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Aspergillus Bronchitis at Localised Mucus Plug in an Immunocompetent Patient. 免疫正常患者的曲霉菌性支气管炎局部粘液堵塞。

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Respirology Case Reports Pub Date : 2025-03-20 eCollection Date: 2025-03-01 DOI: 10.1002/rcr2.70104

Kai Yamazaki, Yukihiro Horio, Kazuhito Hatanaka, Takashi Yaguchi, Kozaburo Sadahiro, Kohei Umemoto, Shigeaki Hattori, Katsuyoshi Tomomatsu, Naoki Hayama, Yoko Ito, Tsuyoshi Oguma, Koichiro Asano

引用次数: 0

A Spontaneous Pneumomediastinum During an Asthma Exacerbation. 哮喘发作时自发性纵隔气肿。

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Respirology Case Reports Pub Date : 2025-03-20 eCollection Date: 2025-03-01 DOI: 10.1002/rcr2.70156

Joseph Derry, Harshana Bandara

引用次数: 0

Cryoextraction of Subacute, Adhesive and Immobile Airway Blood Clot With Short Freezing Time: A Case Report. 冷冻时间短的亚急性粘着性固定气道血凝块冷冻取出1例。

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Respirology Case Reports Pub Date : 2025-03-18 eCollection Date: 2025-03-01 DOI: 10.1002/rcr2.70155

Takashi Nishihara, Takayuki Takimoto, Eiji Sugimoto, Shojiro Minomo, Toru Arai

引用次数: 0

Therapeutic Whole Lung Lavage for Pulmonary Alveolar Proteinosis: Technique With Continuous Video-Enabled Double Lumen Endotracheal Tube. 全肺灌洗治疗肺泡蛋白沉积症：连续视频双腔气管内管技术。

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Respirology Case Reports Pub Date : 2025-03-18 eCollection Date: 2025-03-01 DOI: 10.1002/rcr2.70153

Kevin Davidson

引用次数: 0

A Case of Myasthenia Gravis and Stiff-Person Syndrome That Improved After Extended Thymectomy. 延长胸腺切除术后重症肌无力及僵硬综合征好转1例。

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Respirology Case Reports Pub Date : 2025-03-17 eCollection Date: 2025-03-01 DOI: 10.1002/rcr2.70149

Shoji Okado, Tetsuya Mizuno, Yuta Kawasumi, Yuka Kadomatsu, Toyofumi Fengshi Chen-Yoshikawa

引用次数: 0

Placement of a Customised Y-Shaped Silicone Stent via the Transthoracic Approach for Closing a Large Bronchial Stump Fistula. 经胸入路置入定制的y形硅胶支架，用于关闭大支气管残端瘘。

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Respirology Case Reports Pub Date : 2025-03-17 eCollection Date: 2025-03-01 DOI: 10.1002/rcr2.70152

Junqi Zhu, Chan Xu, Honglei Tao, Shunxin Xin, Weihua Xu

引用次数: 0