Respirology Case ReportsPub Date : 2025-09-29eCollection Date: 2025-10-01DOI: 10.1002/rcr2.70354
Man Luo, Yang Liu, Xianyao Yang, Mei Liu, Chao Yu
{"title":"Paragonimiasis Diagnosed Through Detection of Parasitic Ova in Pleural Effusion: A Clinical Case Report.","authors":"Man Luo, Yang Liu, Xianyao Yang, Mei Liu, Chao Yu","doi":"10.1002/rcr2.70354","DOIUrl":"10.1002/rcr2.70354","url":null,"abstract":"<p><p>Paragonimiasis, a chronic zoonotic parasitic infection caused by <i>Paragonimus</i> species, is frequently misdiagnosed due to its nonspecific clinical presentation and low disease awareness. We report a case of a 42-year-old male who was admitted following head and chest trauma. Initial chest CT revealed bilateral pulmonary contusions, a right rib fracture, and a significant pleural effusion, consistent with traumatic lung injury. Routine blood tests showed elevated white blood cells and neutrophils, but eosinophil counts remained within the normal range. Closed thoracic drainage was performed, and unexpectedly, numerous <i>Paragonimus</i> eggs and cholesterol crystals were identified in the pleural fluid. Subsequent serological testing confirmed positive parasite-specific antibodies, and genetic sequencing verified <i>Paragonimus</i> infection. Combined with epidemiological evidence from the patient's history, paragonimiasis was incidentally diagnosed in a patient who presented with a traumatic fracture and pleural effusion. The patient showed marked clinical improvement after treatment with praziquantel. This case underscores that normal eosinophil levels do not exclude paragonimiasis and that imaging findings can be misleading in the context of trauma. A thorough history-taking and comprehensive multimodal evaluation are essential for accurate diagnosis and management of pleural effusion in trauma patients to prevent oversight or misdiagnosis.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 10","pages":"e70354"},"PeriodicalIF":0.8,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12479718/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145207921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Respirology Case ReportsPub Date : 2025-09-29eCollection Date: 2025-10-01DOI: 10.1002/rcr2.70347
Albert Teng, Tzy Harn Chua, Chun Yuen Chow, Yi Hern Tan
{"title":"Bilateral Spontaneous Pneumothorax in a Young Gentleman.","authors":"Albert Teng, Tzy Harn Chua, Chun Yuen Chow, Yi Hern Tan","doi":"10.1002/rcr2.70347","DOIUrl":"10.1002/rcr2.70347","url":null,"abstract":"<p><p>Bilateral spontaneous pneumothorax is a rare condition that occurs mainly in patients with underlying lung disease. We report the case of a 26-year-old Chinese male with a history of smoking who presented with sudden onset of chest tightness and dyspnoea. Chest radiography revealed bilateral pneumothoraxes, prompting the insertion of bilateral chest tubes. Further imaging with high-resolution computed tomography of the chest revealed multiple bilateral, thin-walled cysts with relative sparing of the lung bases and tiny peripheral nodules. The patient underwent bilateral video-assisted thoracoscopic surgery with bullectomy, pleurodesis, and surgical lung biopsy. Histopathological examination revealed cysts lined by Langerhans cells with eosinophilic infiltration, establishing the diagnosis of pulmonary Langerhans cell histiocytosis (PLCH). This case highlights the importance of considering cystic lung diseases, particularly PLCH, in young smokers presenting with spontaneous bilateral pneumothorax. Radiologic and histopathologic correlation is essential for definitive diagnosis. Smoking cessation remains the cornerstone of management.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 10","pages":"e70347"},"PeriodicalIF":0.8,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12479123/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145201743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sarcoidosis With Pulmonary and Bone Marrow Involvement Following Chemotherapy in a Cancer Patient.","authors":"Ken Shirahase, Tadao Nagasaki, Masato Muraki, Tomoko Wakasa, Soichiro Hanada, Masamichi Iwai, Yuji Tohda, Hisako Matsumoto","doi":"10.1002/rcr2.70353","DOIUrl":"10.1002/rcr2.70353","url":null,"abstract":"<p><p>Sarcoidosis is a multisystem granulomatous disease that rarely involves the bone marrow and is particularly uncommon during chemotherapy. A 56-year-old Japanese woman with stage IIIc fallopian tube carcinoma developed persistent high-grade fever and new bilateral pulmonary nodules two weeks after paclitaxel-carboplatin and bevacizumab therapy, which was complicated by neutropenia. Initial evaluations, including imaging, microbiological studies and bronchoscopy, excluded infection and malignancy recurrence. Histological analysis of bone marrow and transbronchial lung biopsy specimens demonstrated non-caseating granulomas, confirming sarcoidosis despite normal serum angiotensin-converting enzyme levels and absence of lymphadenopathy. Her fever and pulmonary nodules resolved spontaneously without corticosteroid therapy. This case underscores the importance of considering sarcoidosis in the differential diagnosis of fever and new pulmonary lesions in patients undergoing chemotherapy. Early histopathological confirmation is essential to avoid misdiagnosis and guide appropriate management.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 10","pages":"e70353"},"PeriodicalIF":0.8,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12463489/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145187209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Respirology Case ReportsPub Date : 2025-09-25eCollection Date: 2025-09-01DOI: 10.1002/rcr2.70351
{"title":"Correction to \"Bronchiolar Adenoma/Ciliated Muconodular Papillary Tumour With a 17-Year Follow-Up: A Case Report\".","authors":"","doi":"10.1002/rcr2.70351","DOIUrl":"https://doi.org/10.1002/rcr2.70351","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1002/rcr2.70337.].</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 9","pages":"e70351"},"PeriodicalIF":0.8,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12461401/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145187199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Respirology Case ReportsPub Date : 2025-09-25eCollection Date: 2025-10-01DOI: 10.1002/rcr2.70361
Sahan Chandrasekara, Eli Dabscheck, Mary Spiteri, Renel Cuesta, Teanau Roebuck, Matthew T Naughton
{"title":"A Case of Mild OSA Exacerbated by Alcohol Use.","authors":"Sahan Chandrasekara, Eli Dabscheck, Mary Spiteri, Renel Cuesta, Teanau Roebuck, Matthew T Naughton","doi":"10.1002/rcr2.70361","DOIUrl":"10.1002/rcr2.70361","url":null,"abstract":"<p><p>Obstructive sleep apnoea (OSA) is highly prevalent and exacerbated by alcohol consumption. With an increasing uptake of unsupervised home-based sleep studies for diagnosis, alcohol use can significantly confound results and impact clinical management. We present the case of a 65 year-old male referred for OSA evaluation. An initial home sleep study, performed in the setting of significant alcohol intake, demonstrated moderate OSA (AHI 22.1) with predominantly supine sleep (99% of total sleep time). A subsequent alcohol-free in-lab study revealed only mild OSA (7.5) with predominantly non-supine sleep (41.9% of total sleep time supine). This marked change reflects the effect of alcohol on OSA severity and sleep architecture. Our case emphasises the importance of documenting alcohol use prior to and during sleep studies and the incorporation of alcohol reduction in OSA management for selected patients.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 10","pages":"e70361"},"PeriodicalIF":0.8,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12463488/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145187190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Respirology Case ReportsPub Date : 2025-09-22eCollection Date: 2025-09-01DOI: 10.1002/rcr2.70355
Chih-Huan Lu, Brooks T Kuhn, Michael Schivo, Chinh Phan, Ken Y Yoneda, Jeremy J Kim
{"title":"Two-Staged Bronchoscopic Lung Volume Reduction: A Single US Academic Center Retrospective Analysis Demonstrating Reduction in Pneumothorax.","authors":"Chih-Huan Lu, Brooks T Kuhn, Michael Schivo, Chinh Phan, Ken Y Yoneda, Jeremy J Kim","doi":"10.1002/rcr2.70355","DOIUrl":"10.1002/rcr2.70355","url":null,"abstract":"<p><p>Staged Bronchoscopic lung volume reduction (BLVR) has been proposed to reduce the risk of pneumothorax in patients with emphysema, though evidence to date is limited. We present a retrospective series from a single US academic centre, evaluating pneumothorax and other complications following staged BLVR. Seventeen patients underwent staged BLVR at our centre. Two illustrative cases are presented: (1) a case of pneumothorax post-staged BLVR managed conservatively without chest tube insertion, and (2) a patient who initially developed pneumothorax after single-stage BLVR, subsequently completing staged BLVR without complications. Overall, the pneumothorax rate within 45 days was 11.8%, and none of the events required tube drainage or valve removal. This retrospective analysis suggests that staged BLVR may reduce the incidence of pneumothorax. Larger, randomised controlled trials are warranted to confirm these potential benefits.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 9","pages":"e70355"},"PeriodicalIF":0.8,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12454916/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145139010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Respirology Case ReportsPub Date : 2025-09-22eCollection Date: 2025-09-01DOI: 10.1002/rcr2.70349
{"title":"Correction to \"Asbestosis Requiring Lung Transplantation in a Retired Hairdresser: An Occupational Exposure to Comb Through\".","authors":"","doi":"10.1002/rcr2.70349","DOIUrl":"https://doi.org/10.1002/rcr2.70349","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1002/rcr2.70283.].</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 9","pages":"e70349"},"PeriodicalIF":0.8,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12454674/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145138971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Respirology Case ReportsPub Date : 2025-09-22eCollection Date: 2025-09-01DOI: 10.1002/rcr2.70358
Eitetsu Koh
{"title":"Successful Combined Autologous Blood and Minocycline Pleurodesis for Intractable Bilateral Pneumothorax in an Elderly Patient With Combined Pulmonary Fibrosis and Emphysema: A Case Report.","authors":"Eitetsu Koh","doi":"10.1002/rcr2.70358","DOIUrl":"10.1002/rcr2.70358","url":null,"abstract":"<p><p>Bilateral pneumothorax in elderly patients with combined pulmonary fibrosis and emphysema (CPFE) is rare and often precludes surgery. We report an 86-year-old man with CPFE and a persistent air leak unresponsive to tube drainage. Combined pleurodesis via the chest tube using 50 mL autologous blood and 100 mg minocycline diluted in 50 mL saline achieved cessation after two sessions 3 days apart. Two months later, contralateral pneumothorax occurred and was successfully treated using the same protocol. No procedure-related complications were observed; no recurrence was seen at 6-month follow-up. This simple bedside approach may be a practical option when surgery is contraindicated.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 9","pages":"e70358"},"PeriodicalIF":0.8,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12454911/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145138966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Respirology Case ReportsPub Date : 2025-09-22eCollection Date: 2025-09-01DOI: 10.1002/rcr2.70350
{"title":"Correction to \"Endobronchial Lipoma Treated With Endoscopic Microwave Coagulation to Relieve Atelectasis: The First Case Report\".","authors":"","doi":"10.1002/rcr2.70350","DOIUrl":"https://doi.org/10.1002/rcr2.70350","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1002/rcr2.70313.].</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 9","pages":"e70350"},"PeriodicalIF":0.8,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12454669/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145138991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hemiclamshell Resection of a Ruptured Mediastinal Teratoma Exhibiting Pancreatic Differentiation.","authors":"Yuri Enomoto, Yoshio Nakano, Hiroyuki Fukuda, Yoko Yamamoto, Naoki Ikeda, Yumiko Yasuhara, Iwao Gohma","doi":"10.1002/rcr2.70345","DOIUrl":"10.1002/rcr2.70345","url":null,"abstract":"<p><p>Mediastinal teratomas demonstrating unidirectional pancreatic differentiation are exceedingly rare. We describe a 36-year-old woman with progressively worsening anterior chest pain. Computed tomography demonstrated a 5.9 cm multilocular cystic mass in the anterior mediastinum, accompanied by pleural and pericardial effusions. Given the lesion's size and presumed inflammatory reaction, we performed radical excision via a hemiclamshell incision. Histopathology revealed predominantly pancreatic acinar tissue with scattered non-pancreatic epithelial elements, prompting reclassification as a mediastinal teratoma rather than ectopic pancreas. Focal epithelial disruption was regarded as the nidus of the surrounding inflammation. The patient's postoperative course was uneventful. This report underscores the need to include teratoma in the differential diagnosis of anterior mediastinal lesions initially interpreted as ectopic pancreas and illustrates the value of the hemiclamshell approach for achieving complete, atraumatic resection when extensive local adhesions are present.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 9","pages":"e70345"},"PeriodicalIF":0.8,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12444644/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145114473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}