{"title":"Localization of micro bronchial stump fistulas via guidewire exploration: A case report.","authors":"Jieqiong Wang, Yan Hang, Zhongliang He, Shunxin Xin, Congbin Peng, Guohong Mo, Weihua Xu","doi":"10.1002/rcr2.70081","DOIUrl":"10.1002/rcr2.70081","url":null,"abstract":"<p><p>Bronchopleural fistula (BPF), a common complication of lobectomy, is a pathological communication between the bronchus and the pleural space. The bronchial stump fistula (BSF), which is located on the bronchial stump, is a specific type of BPF. BSF can be directly diagnosed via bronchoscopy. However, identification becomes difficult when the BSF is very small (less than 1 mm), referred to as micro BSF in this study because it cannot be found during bronchoscopic exploration. This clinical dilemma easily leads to misdiagnosis of BSF. In this paper, a new procedure for locating micro BSFs using guidewire exploration was reported. This innovative approach involves the use of a guidewire to detect suspected micro BSFs. If the guidewire successfully penetrates the bronchial stump, it indicates the presence of a micro BSF; otherwise, there is none. After precise localization of three micro BSFs, submucosal injection of lauromacrogol around them was performed followed by thoracic fenestration.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"12 12","pages":"e70081"},"PeriodicalIF":0.8,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11613215/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142773424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Parsonage-Turner-syndrome associated with <i>Mycoplasma pneumoniae</i> infection.","authors":"Fabian Leo, Christian Grohé","doi":"10.1002/rcr2.70071","DOIUrl":"https://doi.org/10.1002/rcr2.70071","url":null,"abstract":"<p><p>Neurological complications in the course of community-acquired pneumonia indicate that <i>Mycoplasma pneumoniae</i> may be the causative pathogen. Parsonage-Turner-Syndrome, characterized by neuralgic shoulder pain and amyotrophy, has rarely been reported in this context.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"12 12","pages":"e70071"},"PeriodicalIF":0.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11608758/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142773428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Respirology Case ReportsPub Date : 2024-11-30eCollection Date: 2024-12-01DOI: 10.1002/rcr2.70069
Rachel Shadbolt, Matthew Ing, Michaela Donaghy, Krist Ewe, Y C Gary Lee, Edward Fysh
{"title":"Confirmed <i>Treponema pallidum</i> pleural effusion in patient with known syphilis.","authors":"Rachel Shadbolt, Matthew Ing, Michaela Donaghy, Krist Ewe, Y C Gary Lee, Edward Fysh","doi":"10.1002/rcr2.70069","DOIUrl":"https://doi.org/10.1002/rcr2.70069","url":null,"abstract":"<p><p>Pulmonary and pleural involvement in <i>Treponema pallidum</i> infection is uncommon. Previously reported syphilis-related pleural effusions have been described largely based on clinical features combined with positive syphilis serology rather than the detection of <i>T pallidum</i> in pleural fluid or pleural biopsy. We report a case of secondary syphilis and confirmed syphilitic pleural effusion via thoracentesis.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"12 12","pages":"e70069"},"PeriodicalIF":0.8,"publicationDate":"2024-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11608128/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142773412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Convex endobronchial ultrasound bronchoscope may enhance visualization and diagnosis by respiratory physicians: Clinical image of an endoscopic ultrasound with bronchoscope.","authors":"Suzuka Matsuoka, Yuki Takigawa, Ken Sato, Tomoyoshi Inoue, Hiromi Watanabe, Kenichiro Kudo, Akiko Sato, Keiichi Fujiwara, Takuo Shibayama","doi":"10.1002/rcr2.70072","DOIUrl":"10.1002/rcr2.70072","url":null,"abstract":"<p><p>Herein, we present the detection of two cystic lesions via the transesophageal route using endobronchial ultrasound and emphasize the fact that understanding the anatomy may enhance the diagnostic yield.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"12 11","pages":"e70072"},"PeriodicalIF":0.8,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11586573/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142717437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Respirology Case ReportsPub Date : 2024-11-25eCollection Date: 2024-11-01DOI: 10.1002/rcr2.70052
Matteo Schisano, Alessandro Libra, Giorgio Morana, Carlo Vancheri, Lucia Spicuzza
{"title":"Adaptive servo-ventilation for the treatment of intrathecal baclofen-induced central sleep apnea: A case report.","authors":"Matteo Schisano, Alessandro Libra, Giorgio Morana, Carlo Vancheri, Lucia Spicuzza","doi":"10.1002/rcr2.70052","DOIUrl":"10.1002/rcr2.70052","url":null,"abstract":"<p><p>Baclofen is a common muscle relaxant agent used in a number of neurological disorders acting at central level and potentially causing adverse respiratory events, still largely unknown at therapeutic doses. We present the case of a young woman with spastic tetraparesis secondary to perinatal asphyxia treated with a standard dose of intrathecal baclofen who developed nocturnal symptoms, somnolence and memory loss during the day. Nocturnal cardio-respiratory sleep monitoring showed a high number of central sleep apneas (CSA). The patient was adapted and treated with a positive air pressure device, Adaptative Servo-Ventilator, specific designed to treat CSA particularly in patients with heart failure. The treatment was well tolerated and within few days CSA was reversed. The patient reported a feeling of restful sleep and disappearance of morning tiredness. The efficacy of the treatment was verified with nocturnal cardio-respiratory monitoring after 2 months and complete resolution of all symptoms was also confirmed.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"12 11","pages":"e70052"},"PeriodicalIF":0.8,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11588345/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142717508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anna Russo, Vittorio Viglione, Linda Franzese, Vittorio Patanè, Tullio Valente, Fabio Perrotta, Alfonso Reginelli
{"title":"Unveiling the radiological odyssey: Navigating the interstitial with artificial intelligence.","authors":"Anna Russo, Vittorio Viglione, Linda Franzese, Vittorio Patanè, Tullio Valente, Fabio Perrotta, Alfonso Reginelli","doi":"10.1002/rcr2.1413","DOIUrl":"10.1002/rcr2.1413","url":null,"abstract":"<p><p>This study examines the radiological and clinical evolution of a case involving mixed idiopathic pulmonary fibrosis and chronic hypersensitivity pneumonitis, utilizing conventional CT imaging and artificial intelligence tool. Through a series of exams and clinical assessments, the patient was followed for over 3 years, highlighting the challenge in differentiating these interstitial pathologies and the importance of a multidisciplinary approach. The radiological progression towards pulmonary fibrosis was correlated with clinical symptoms, emphasizing the significance of early diagnosis and regular follow-up. The combined use of advanced technologies offers a more comprehensive framework in managing complex lung diseases, enhancing the quality of care and understanding of interstitial pathologies.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"12 11","pages":"e01413"},"PeriodicalIF":0.8,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11588411/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142717567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Respirology Case ReportsPub Date : 2024-11-25eCollection Date: 2024-11-01DOI: 10.1002/rcr2.70064
Roger Winters, Lindsay M Forbes, Dunbar Ivy, Carlyne Cool, Bryan D Park, Peter Hountras, David Badesch, Sue Gu, Edda Spiekerkoetter, Roham Zamanian, Stacey LeierGluck, Todd M Bull
{"title":"Case report: A finding of PVOD and PAH in first degree relatives suggests shared heritable risk and overlapping features of both pulmonary vascular diseases.","authors":"Roger Winters, Lindsay M Forbes, Dunbar Ivy, Carlyne Cool, Bryan D Park, Peter Hountras, David Badesch, Sue Gu, Edda Spiekerkoetter, Roham Zamanian, Stacey LeierGluck, Todd M Bull","doi":"10.1002/rcr2.70064","DOIUrl":"10.1002/rcr2.70064","url":null,"abstract":"<p><p>Pulmonary veno-occlusive disease (PVOD) is a rare form of pulmonary vascular disease that is difficult to distinguish clinically from pulmonary arterial hypertension (PAH). Multiple genes have been implicated in disease pathogenesis in PAH and PVOD and the diseases are thought to be genetically distinct. In this report we present a case of first-degree relatives with pathological evidence of PVOD and PAH. The index patient was diagnosed with PAH at age 42, was treated with escalating pulmonary vasodilator therapy, but eventually succumbed to her disease. On autopsy, her pathology was consistent with PAH. Her son was diagnosed with PAH at age 16, did well on pulmonary vasodilator therapy for over 10 years, but ultimately developed refractory right ventricular failure and received a heart and lung transplantation. Pathology of his explanted lung was consistent with PVOD, and genetic testing was negative for recognized variants that cause PAH or PVOD.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"12 11","pages":"e70064"},"PeriodicalIF":0.8,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11588353/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142717436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Immune checkpoint inhibitor-induced autoimmune limbic encephalitis with positivity for anti-Hu antibodies in a patient with small-cell lung cancer: A case report and literature review.","authors":"Lynn Nakahara, Shun Matsuura, Ryo Suzuki, Akira Kawamura, Takumi Nagasaki, Takafumi Masuda, Kotaro Yamada, Ryuuichi Nakamura, Toshiya Hiramatsu, Norimichi Akiyama, Kazuki Tanaka, Naoki Koshimizu, Shota Igasaki","doi":"10.1002/rcr2.70070","DOIUrl":"10.1002/rcr2.70070","url":null,"abstract":"<p><p>In recent years, there has been an increasing number of studies on neurological symptoms induced as paraneoplastic neurological syndrome (PNS) or neurological immune-related adverse events (irAEs) in patients treated with immune checkpoint inhibitors (ICIs). Herein, we report a 68-year-old male patient with small-cell lung cancer who developed memory impairment and autonomic nervous system dysfunction after three courses of carboplatin, etoposide, and durvalumab therapy. Brain magnetic resonance imaging revealed hyperintense areas restricted to the bilateral temporal lobes. Moreover, based on the blood test results, the patient was strongly positive for anti-neuronal nuclear antibodies. Hence, he was diagnosed with autoimmune limbic encephalitis (ALE). Corticosteroid pulse therapy was administered. After treatment, the patient exhibited gradual improvement in memory impairment. However, while tapering the prednisolone dose, the patient exhibited relapse of memory disturbance owing to ALE. It is challenging to distinguish PNS from neurological irAEs. However, ICI-induced ALE with positivity for anti-Hu antibodies has an extremely poor prognosis.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"12 11","pages":"e70070"},"PeriodicalIF":0.8,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11586685/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142717553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Respirology Case ReportsPub Date : 2024-11-25eCollection Date: 2024-11-01DOI: 10.1002/rcr2.70068
Ad Rian Chong, Khai Lip Ng, Nai-Chien Huan, Nur Husna Mohd Aminudin, Maryam Ahmad Sharifuddin, Raja Nor Adilla Raja Rahaizat, Kasuma Mohamed Nordin
{"title":"Unveiling a rare haemorrhagic malignant pleural effusion: The role of medical thoracoscopy in diagnosing primary pleural angiosarcoma.","authors":"Ad Rian Chong, Khai Lip Ng, Nai-Chien Huan, Nur Husna Mohd Aminudin, Maryam Ahmad Sharifuddin, Raja Nor Adilla Raja Rahaizat, Kasuma Mohamed Nordin","doi":"10.1002/rcr2.70068","DOIUrl":"10.1002/rcr2.70068","url":null,"abstract":"<p><p>Primary pleural angiosarcoma (PPA) is a rare and challenging tumour to diagnose, often mistaken for other malignancies such as mesothelioma and lung cancer due to overlapping clinical and imaging features. We report a 52-year-old woman who presented with progressive shortness of breath and pleuritic chest pain. Imaging studies and thoracentesis revealed a large haemorrhagic left pleural effusion. Medical thoracoscopy (MT) showed a thickened and lobulated parietal pleura with multiple nodular lesions. Histopathological examination confirmed a diagnosis of angiosarcoma, characterized by pleomorphic tumour cells, a high Ki67 proliferation index and positive immunohistochemical markers, including CD31, D2-40, Vimentin, and Factor VIII. Tragically, the patient developed a hospital-acquired infection and passed away before any definitive treatment for the angiosarcoma could be initiated. This case underscores the diagnostic complexities of PPA and highlights the utility of MT in identifying this rare malignancy.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"12 11","pages":"e70068"},"PeriodicalIF":0.8,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11586632/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142717562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Respirology Case ReportsPub Date : 2024-11-21eCollection Date: 2024-11-01DOI: 10.1002/rcr2.70067
Nathan Harb, Julia Fattore, Mayuran Saththianathan, Stephen Parsons
{"title":"Thoracic splenosis: Precision medicine can prevent thoracic surgery.","authors":"Nathan Harb, Julia Fattore, Mayuran Saththianathan, Stephen Parsons","doi":"10.1002/rcr2.70067","DOIUrl":"10.1002/rcr2.70067","url":null,"abstract":"<p><p>Thoracic splenosis is a rare condition referring to the auto-transplantation of splenic tissue into the thoracic cavity following splenic trauma. We present a case of thoracic splenosis in a 62-year-old man who at the age of 17 suffered three gunshot wounds to the posterior thorax and abdomen, requiring a splenectomy and intercostal catheter insertion. In 2007, he underwent a thoracotomy and biopsy of a left sided pulmonary mass which was complicated by a haemothorax requiring an emergent return to theatre and rib resection to achieve haemostasis. The biopsy revealed granulation tissue. In 2023, Technetium-99m (Tc-99m) heat-damaged erythrocyte scintigraphy confirmed the diagnosis of thoracic splenosis. This case highlights the importance of recognizing this uncommon condition to prevent unnecessary investigation, as well as the use of Tc-99m heat-damaged erythrocyte scintigraphy to confirm the diagnosis.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"12 11","pages":"e70067"},"PeriodicalIF":0.8,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11581776/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142689152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}