Respirology Case Reports最新文献_第3页

Rescue Diagnosis of Upper-Lobar Station 12U Lymph Nodes Using the Thin Convex-Probe EBUS Bronchoscope (BF-UCP190F): A Report of Two Cases. 薄凸探头EBUS支气管镜（BF-UCP190F）抢救诊断上叶站12U淋巴结2例

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Respirology Case Reports Pub Date : 2026-09-16 eCollection Date: 2026-09-01 DOI: 10.1002/rcr2.70762

Toki Kitano, Yuki Takigawa, Ken Sato, Mayu Goda, Hitoshi Hara, Tomoya Osedo, Yuto Sasano, Keisuke Shiraha, Suzuka Matsuoka, Jun Nishimura, Hiromi Watanabe, Kenichiro Kudo, Keiichi Fujiwara

{"title":"Rescue Diagnosis of Upper-Lobar Station 12U Lymph Nodes Using the Thin Convex-Probe EBUS Bronchoscope (BF-UCP190F): A Report of Two Cases.","authors":"Toki Kitano, Yuki Takigawa, Ken Sato, Mayu Goda, Hitoshi Hara, Tomoya Osedo, Yuto Sasano, Keisuke Shiraha, Suzuka Matsuoka, Jun Nishimura, Hiromi Watanabe, Kenichiro Kudo, Keiichi Fujiwara","doi":"10.1002/rcr2.70762","DOIUrl":"https://doi.org/10.1002/rcr2.70762","url":null,"abstract":"BF-UCP190F (Olympus) is a newly developed thin convex-probe endobronchial ultrasound (TCP-EBUS) bronchoscope, improving access to distal bronchi. We report two cases in which TCP-EBUS enabled successful endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) of the upper-lobar station 12U lymph node (#12U LN) via B3 after conventional bronchoscopic forceps sampling failed to provide a definitive diagnosis. In the first case, forceps biopsy of a left upper lobe tumour was non-diagnostic; TCP-EBUS-guided EBUS-TBNA of the left #12U LN established lung adenocarcinoma with N1 involvement. In the second case, the initial bronchoscopy yielded only cytological evidence of carcinoma without histological confirmation; TCP-EBUS-guided sampling of the right #12U LN revealed metastatic small cell carcinoma. In both cases, the pathological diagnosis of EBUS-TBNA guided subsequent treatment. These cases suggest that BF-UCP190F expands the diagnostic range of bronchoscopy and may serve as a valuable rescue technique for sampling upper lobar hilar lymph nodes in clinical practice.","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"14 9","pages":"e70762"},"PeriodicalIF":0.7,"publicationDate":"2026-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13581433/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148991768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rapid Onset of Mesalazine-Induced Eosinophilic Pneumonia Manifesting 7 Days After Initiation: A Case Report. 美沙拉嗪引起的嗜酸性粒细胞性肺炎在发病7天后迅速发作：1例报告。

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Respirology Case Reports Pub Date : 2026-09-16 eCollection Date: 2026-09-01 DOI: 10.1002/rcr2.70758

Toshiaki Inazaki, Kenichiro Takeda, Mana Iwasaki, Hiroki Tajima, Yu Shionoya, Ryutaro Hirama, Shun Sato, Akira Naito, Takeshi Kawasaki, Jun Ikari, Satoko Kageyama, Jun-Ichiro Ikeda, Takuji Suzuki

引用次数: 0

Bilateral Bloody Pleural Effusions With Discordant Cellular Patterns: A Case of Concurrent Parapneumonic Effusion and Dressler Syndrome. 双侧带血胸腔积液伴不一致细胞形态：并发肺旁积液和Dressler综合征1例。

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Respirology Case Reports Pub Date : 2026-09-16 eCollection Date: 2026-09-01 DOI: 10.1002/rcr2.70764

Yoshitsugu Narumi, Susumu Hoshino, Midori Yamakawa, Yoshiko Amano

引用次数: 0

Hot Tub Lung: Misdiagnosed Hypersensitivity Pneumonitis Revealing a Mycobacterial Aetiology-A Case Report and Literature Review. 热浴肺：被误诊为分枝杆菌病原学的超敏性肺炎1例报告及文献复习。

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Respirology Case Reports Pub Date : 2026-09-15 eCollection Date: 2026-09-01 DOI: 10.1002/rcr2.70741

Fadi Abualhommos, Rahaf Fetyani, Yasmeen Butt, Michael Gotway, Abeer Almajali, Jehad Azar

{"title":"Hot Tub Lung: Misdiagnosed Hypersensitivity Pneumonitis Revealing a Mycobacterial Aetiology-A Case Report and Literature Review.","authors":"Fadi Abualhommos, Rahaf Fetyani, Yasmeen Butt, Michael Gotway, Abeer Almajali, Jehad Azar","doi":"10.1002/rcr2.70741","DOIUrl":"10.1002/rcr2.70741","url":null,"abstract":"Hot tub lung (HTL) is a rare granulomatous pneumonitis caused by inhalational exposure to Mycobacterium avium complex (MAC)-contaminated hot tub water, with debated pathogenesis encompassing both hypersensitivity and infectious mechanisms. A 66-year-old woman with progressive exertional dyspnea was initially misdiagnosed with non-fibrotic hypersensitivity pneumonitis attributed to pheasant exposure and treated with corticosteroids and mycophenolate without improvement. High-resolution CT demonstrated diffuse centrilobular nodules with air-trapping. Surgical lung biopsy revealed bronchiolocentric non-necrotizing granulomas with rare MAC organisms despite negative bronchoalveolar lavage cultures. Detailed clinical history disclosed daily indoor hot tub use coinciding with symptom onset. Following hot tub cessation and initiation of azithromycin, ethambutol and rifabutin, she ultimately achieved complete clinical and radiologic resolution. HTL represents a heterogeneous spectrum from immune-mediated hypersensitivity to true mycobacterial infection. Persistent interstitial lung disease despite ongoing immunosuppression should prompt a thorough hot tub exposure history and selected patients may require antimycobacterial therapy alongside exposure cessation.","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"14 9","pages":"e70741"},"PeriodicalIF":0.7,"publicationDate":"2026-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13575854/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148978217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recurrent Asthma Exacerbations Secondary to Gastric Stenosis After Gastric Band Slippage: Case Report and Literature Review. 胃带滑脱后胃狭窄继发哮喘复发：病例报告及文献复习。

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Respirology Case Reports Pub Date : 2026-09-15 eCollection Date: 2026-09-01 DOI: 10.1002/rcr2.70761

Gerardo Arwi, Adriana Avram, Philip Bardin

引用次数: 0

Pulmonary Amyloidosis Diagnosed by Transbronchial Lung Biopsy: A Three-Case Series With Diverse Radiological Manifestations. 经支气管肺活检诊断肺淀粉样变：三例不同影像学表现。

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Respirology Case Reports Pub Date : 2026-09-15 eCollection Date: 2026-09-01 DOI: 10.1002/rcr2.70757

Masaki Tanaka, Yuri Ozaki, Takuo Otsuka, Takahide Hongo, Mari Tone, Yuhei Kinehara, Shoichi Ihara, Yoshito Takeda, Ryu Jokoji, Isao Tachibana

{"title":"Pulmonary Amyloidosis Diagnosed by Transbronchial Lung Biopsy: A Three-Case Series With Diverse Radiological Manifestations.","authors":"Masaki Tanaka, Yuri Ozaki, Takuo Otsuka, Takahide Hongo, Mari Tone, Yuhei Kinehara, Shoichi Ihara, Yoshito Takeda, Ryu Jokoji, Isao Tachibana","doi":"10.1002/rcr2.70757","DOIUrl":"https://doi.org/10.1002/rcr2.70757","url":null,"abstract":"Pulmonary amyloidosis is a rare disease with diverse radiological manifestations that may mimic malignancy or diffuse interstitial lung disease. Although conventional forceps transbronchial lung biopsy (TBLB) is an established less invasive diagnostic method, its clinical role may differ according to disease presentation. We report three patients with pulmonary amyloidosis diagnosed by conventional forceps TBLB. Two presented with nodular lesions mimicking malignancy; TBLB established the diagnosis, and systemic evaluation showed no extrapulmonary involvement, supporting localized pulmonary amyloidosis. The third presented with progressive weight loss and diffuse interlobular septal thickening. TBLB unexpectedly demonstrated pulmonary amyloid deposition, prompting systemic and haematological evaluation that revealed systemic AL amyloidosis associated with multiple myeloma. These cases illustrate distinct roles of conventional forceps TBLB: distinguishing localized nodular amyloidosis from malignancy and, in diffuse alveolar-septal disease, providing an initial clue prompting evaluation for systemic amyloidosis.","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"14 9","pages":"e70757"},"PeriodicalIF":0.7,"publicationDate":"2026-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13578924/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148991790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Individualized Stent for Tracheal Fistula Complicating Tracheostomy Following Esophagectomy. 食管切除术后气管造口术后气管瘘的个体化支架治疗。

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Respirology Case Reports Pub Date : 2026-09-15 eCollection Date: 2026-09-01 DOI: 10.1002/rcr2.70755

Xiaerbate Zakeerjiang, Yu ChenYi, Liu Bing, Liu Bin, Liu YaTing, Yuan YiFei

{"title":"Individualized Stent for Tracheal Fistula Complicating Tracheostomy Following Esophagectomy.","authors":"Xiaerbate Zakeerjiang, Yu ChenYi, Liu Bing, Liu Bin, Liu YaTing, Yuan YiFei","doi":"10.1002/rcr2.70755","DOIUrl":"10.1002/rcr2.70755","url":null,"abstract":"Delayed-onset tracheal fistula following esophagectomy with concurrent tracheostomy is rare and poses diagnostic challenges. A 79-year-old female patient with oesophageal squamous cell carcinoma (ESCC) developed a tracheal fistula following esophagectomy and tracheostomy. Repeated bronchoscopies via the tracheostoma failed to visualize the fistula orifice; the diagnosis was confirmed by computed tomography (CT) with oral contrast medium and complete tracheal inspection following temporary removal of the tracheostomy tube. A patient-specific, fully covered self-expandable metallic stent (FCSEMS) was implanted under endoscopic guidance. At 53 days of follow-up, the stent remained well-positioned without aspiration recurrence. The patient ultimately succumbed to distant tumour metastasis and multidrug-resistant bacterial infection. Complete tracheobronchoscopy following temporary decannulation and CT with oral contrast medium facilitates the diagnosis of tracheal fistula. Individualized covered stenting achieves satisfactory fistula occlusion, thereby providing valuable clinical insights for the management of similar complex cases.","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"14 9","pages":"e70755"},"PeriodicalIF":0.7,"publicationDate":"2026-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13575761/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148978171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Underrecognized Cause of Recurrent Spontaneous Pneumothorax: Birt-Hogg-Dubé Syndrome With Isolated Pulmonary Manifestation. 复发性自发性气胸的一个未被认识的原因：孤立肺部表现的birt - hogg - dub<s:1>综合征。

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Respirology Case Reports Pub Date : 2026-09-08 eCollection Date: 2026-09-01 DOI: 10.1002/rcr2.70703

Chia-Ni Liu, Hsiao-Chin Shen, Yi-Chen Yeh

引用次数: 0

Disease-Intrinsic Organising Pneumonia During Biomarker-Confirmed Ulcerative Colitis Remission. 生物标志物证实的溃疡性结肠炎缓解期间的疾病-内在组织性肺炎

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Respirology Case Reports Pub Date : 2026-09-08 eCollection Date: 2026-09-01 DOI: 10.1002/rcr2.70702

Rahaf A Jereisat, Nawras Ibrahim, Maher Dahdel

{"title":"Disease-Intrinsic Organising Pneumonia During Biomarker-Confirmed Ulcerative Colitis Remission.","authors":"Rahaf A Jereisat, Nawras Ibrahim, Maher Dahdel","doi":"10.1002/rcr2.70702","DOIUrl":"10.1002/rcr2.70702","url":null,"abstract":"Organising pneumonia is an increasingly recognised pulmonary manifestation of ulcerative colitis, though nearly all reported cases are attributed to drug-induced aetiology. The 2025 ERS/ATS classification of interstitial pneumonias now explicitly lists ulcerative colitis among secondary causes of cicatricial organising pneumonia, formally recognising a disease-intrinsic mechanism for organising pneumonia in ulcerative colitis. We present a 76-year-old woman with 10-year ulcerative colitis pancolitis on stable mesalamine in biochemical remission (faecal calprotectin 62 μg/g, below the 80 μg/g histological activity threshold) who developed progressive dyspnea. Drug-induced aetiology was systematically excluded: mesalamine had been stable for 10 years, discontinuation produced no improvement, and corticosteroids were required for response. Transbronchial cryobiopsy was initially interpreted as fibrotic non-specific interstitial pneumonia; expert pathology consultation revised the diagnosis to organising pneumonia with Masson bodies, changing management from antifibrotics to corticosteroids, illustrating the clinical consequences of cryobiopsy diagnostic discordance. Bronchoalveolar lavage revealed a neutrophil-predominant profile (42% neutrophils, 3% lymphocytes), atypical for cryptogenic organising pneumonia, which typically shows lymphocytic predominance. This pattern may reflect gut-lung axis immune trafficking in secondary organising pneumonia associated with ulcerative colitis. Concurrent seronegative arthritis was reclassified as ulcerative colitis-associated spondyloarthropathy, removing rheumatoid arthritis-associated interstitial lung disease from the differential. This case extends the sole prior report of organising pneumonia during confirmed ulcerative colitis remission by incorporating biomarker-confirmed remission, systematic drug exclusion, cryobiopsy discordance with treatment-altering consequences and contextualisation within the updated 2025 ERS/ATS classification framework.","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"14 9","pages":"e70702"},"PeriodicalIF":0.7,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13554710/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148920423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Congenital Bronchial Atresia Mimicking Pulmonary Sequestration in the Lower Lobe: A Case Report. 先天性支气管闭锁模拟下肺叶肺隔离一例报告。

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Respirology Case Reports Pub Date : 2026-09-07 eCollection Date: 2026-09-01 DOI: 10.1002/rcr2.70712

Shohei Mitsumata, Kensuke Midorikawa, Kentaro Wakamatsu, Shiro Kaneda, Takuro Futamata, Tsuyoshi Iwanaka, Yuichiro Ueda, So Miyahara, Yoshiko Masuda, Hiroyasu Nakashima, Toshihiko Sato

{"title":"Congenital Bronchial Atresia Mimicking Pulmonary Sequestration in the Lower Lobe: A Case Report.","authors":"Shohei Mitsumata, Kensuke Midorikawa, Kentaro Wakamatsu, Shiro Kaneda, Takuro Futamata, Tsuyoshi Iwanaka, Yuichiro Ueda, So Miyahara, Yoshiko Masuda, Hiroyasu Nakashima, Toshihiko Sato","doi":"10.1002/rcr2.70712","DOIUrl":"10.1002/rcr2.70712","url":null,"abstract":"Congenital bronchial atresia (CBA) is a rare airway anomaly that may radiologically resemble other congenital pulmonary lesions, particularly when it occurs in the lower lobes. A 41-year-old woman was referred for surgical treatment of suspected pulmonary sequestration based on imaging findings. Computed tomography (CT) at the referring hospital showed a cavitary lesion with fluid retention in Segment 7 (S7) of the right lower lobe, with surrounding ground-glass opacity, suggesting infection associated with pulmonary sequestration. Re-evaluation at our institution identified the lesion as a bronchocele with focal hyperinflation, interruption of the segmental bronchus (B7), and a normally distributed pulmonary artery (A7) without aberrant systemic supply. Three-dimensional CT clearly demonstrated these bronchovascular features and supported the diagnosis of CBA. Thoracoscopic right lower lobectomy was performed, and histopathological findings confirmed the diagnosis of CBA. This case highlights the importance of systematic evaluation of bronchial continuity and vascular supply in congenital lower-lobe lesions, for which three-dimensional CT reconstruction may be useful.","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"14 9","pages":"e70712"},"PeriodicalIF":0.7,"publicationDate":"2026-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13551000/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148913469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0