Respirology Case Reports最新文献_第3页

Lazertinib-Induced Rhabdomyolysis in a Patient With Non-Small Cell Lung Cancer: A Case Report.

IF 0.8

Respirology Case Reports Pub Date : 2025-02-05 eCollection Date: 2025-02-01 DOI: 10.1002/rcr2.70105

Seunghun Lee, Juwhan Choi, Sung Yong Lee

引用次数: 0

A Case of Non-Anastomotic Tracheo-Thoracic Gastric Fistula.

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Respirology Case Reports Pub Date : 2025-02-03 eCollection Date: 2025-02-01 DOI: 10.1002/rcr2.70096

Wei He, Ting Wu, Qiang Huang, Wenjing An, Hong Chen, Xiaobo Hu

引用次数: 0

Tuberculosis Associated Chylothorax: A Case Report.

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Respirology Case Reports Pub Date : 2025-02-03 eCollection Date: 2025-02-01 DOI: 10.1002/rcr2.70107

Niharika Malego, Ranjan Sapkota, Aakriti Sharma, Pratikshya Thapaliya

引用次数: 0

Unravelling Granulomatous-Lymphocytic Interstitial Lung Disease: A Case of Common Variable Immunodeficiency With Unusual Clinical Features and Response to Intravenous Immunoglobulin.

IF 0.8

Respirology Case Reports Pub Date : 2025-02-01 DOI: 10.1002/rcr2.70102

Nirosha Pragash, Jennifer Mann, Anton Antonov

{"title":"Unravelling Granulomatous-Lymphocytic Interstitial Lung Disease: A Case of Common Variable Immunodeficiency With Unusual Clinical Features and Response to Intravenous Immunoglobulin.","authors":"Nirosha Pragash, Jennifer Mann, Anton Antonov","doi":"10.1002/rcr2.70102","DOIUrl":"10.1002/rcr2.70102","url":null,"abstract":"Granulomatous-lymphocytic interstitial lung disease (GL-ILD) is a rare pulmonary complication associated with common variable immunodeficiency (CVID), complicating diagnosis due to overlapping symptoms with other chronic respiratory conditions. This case involves a 33-year-old male with a history of sarcoidosis, presenting with recurrent sino-pulmonary infections, mediastinal and axillary lymphadenopathy, and significant splenomegaly. Despite initial treatment with prednisolone, his symptoms persisted, and FDG-PET imaging showed metabolic activity in the sinuses and lymph nodes. Immunological assessment revealed markedly reduced immunoglobulin levels, leading to intravenous immunoglobulin (IVIG) therapy, which resulted in substantial improvement. A critical learning point is recognising that splenomegaly is commonly associated with CVID, which can aid in distinguishing it from other conditions. This case underscores the importance of considering CVID, with or without GL-ILD, as a differential diagnosis in patients with persistent respiratory symptoms and granulomatous lung disease, including sarcoidosis. Further research is needed to optimise treatment strategies for this rare condition.","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 2","pages":"e70102"},"PeriodicalIF":0.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11786966/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143081051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rapid On-Site Digital Histopatholocal Evaluation (RODE) on Endobronchial Ultrasound (EBUS) Mediastinal Lymph Node Cryobiopsy Sampling Using Confocal Laser Microscopy-A Proof-Of-Concept Study.

IF 0.8

Respirology Case Reports Pub Date : 2025-02-01 DOI: 10.1002/rcr2.70103

Hari Kishan Gonuguntla, Belgundi Preeti Vidyasagar, Milap Shah, Sejal B Radia, Somesh Tripathi, Venerino Poletti

{"title":"Rapid On-Site Digital Histopatholocal Evaluation (RODE) on Endobronchial Ultrasound (EBUS) Mediastinal Lymph Node Cryobiopsy Sampling Using Confocal Laser Microscopy-A Proof-Of-Concept Study.","authors":"Hari Kishan Gonuguntla, Belgundi Preeti Vidyasagar, Milap Shah, Sejal B Radia, Somesh Tripathi, Venerino Poletti","doi":"10.1002/rcr2.70103","DOIUrl":"10.1002/rcr2.70103","url":null,"abstract":"The current standard for determining sample adequacy during Endobronchial Ultrasound guided Mediastinal Sampling is ROSE (Rapid on-site Evaluation) on samples obtained by Fine needle Aspiration. There is an increasing interest in Mediastinal Lymph node cryobiopsy, where tissue samples are obtained using a 1.1 mm cryoprobe. Rapid onsite evaluation on cryobiopsy samples can also be performed by imprint cytology. This proof-of-concept study explores the use of Viva Scope 2500 for rapid on-site digital histopathological evaluation of Endobronchial Ultrasound (EBUS) guided mediastinal lymph node cryobiopsy samples. Confocal Laser Microscopy allows for high-resolution imaging and expedites diagnosis. The study involved four cases of mediastinal lymph node cryobiopsy, and the samples obtained were subjected to rapid digital histopathological examination by Viva Scope 2500 (confocal laser microscopy), enabling lesion in tool confirmation and the results obtained were compared with the final conventional histopathology results. Confocal Laser microscopy by Viva Scope 2500 was found to be comparable to conventional histopathology, superior to conventional histopathology in providing rapid on-site diagnosis minimising the time to diagnosis, with added advantage of better sampled tissue preservation for downstream molecular analysis. RODE reduces procedural time and increases confidence in the operator during mediastinal lymph node sampling enabling lesion in tool confirmation. RODE is a better alternative to ROSE and conventional histopathology decreasing the time to diagnosis.","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 2","pages":"e70103"},"PeriodicalIF":0.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11786969/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143081130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Case of Cavitary Lung Metastasis From Prostate Cancer.

IF 0.8

Respirology Case Reports Pub Date : 2025-01-24 eCollection Date: 2025-01-01 DOI: 10.1002/rcr2.70101

Shinnosuke Ohnaka, Mayumi Aoyama, Rino Arai, Saya Hattori, Yusuke Kubo, Shugo Suzuki, Toshihiro Yoshimura, Akinori Ebihara, Toshiaki Morikawa, Hidenobu Shigemitsu, Ichiro Kuwahira

{"title":"A Case of Cavitary Lung Metastasis From Prostate Cancer.","authors":"Shinnosuke Ohnaka, Mayumi Aoyama, Rino Arai, Saya Hattori, Yusuke Kubo, Shugo Suzuki, Toshihiro Yoshimura, Akinori Ebihara, Toshiaki Morikawa, Hidenobu Shigemitsu, Ichiro Kuwahira","doi":"10.1002/rcr2.70101","DOIUrl":"10.1002/rcr2.70101","url":null,"abstract":"A 79-year-old man was found to have multiple nodules in the lung fields on chest computed tomography. Metastatic lung cancer was suspected; however, the primary site remained elusive. After 1 year of follow-up, both the nodules had enlarged. After 2 years, one of the nodules continued to enlarge; however, the other nodule cavitated and decreased in size. Concomitantly, the previously observed fluorodeoxyglucose uptake in the cavitated nodules disappeared. A comprehensive search for the primary cancer included a thoracoscopic lung biopsy which revealed that these nodules were metastatic lung lesions from prostate cancer. Pathological examination revealed necrosis within these metastatic lesions. To date, only three case reports of cavitary lung metastases from prostate cancer have been published; however, no explanation has been provided for the pathological mechanism of cavitation. To our knowledge, this is the first case to provide a potential explanation for cavitation in metastatic lung lesions from prostate cancer.","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 1","pages":"e70101"},"PeriodicalIF":0.8,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11760996/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143048234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unicentric Castleman's Disease of Paraspinal Origin Requiring Differentiation From Schwannoma: Case Report.

IF 0.8

Respirology Case Reports Pub Date : 2025-01-23 eCollection Date: 2025-01-01 DOI: 10.1002/rcr2.70099

Hazuki Fujimoto, Kayoko Okamura, Shunsuke Tauchi, Rei Tsukamoto, Nanami Kida, Miho Ikeda, Yukihisa Hatakeyama, Hisashi Ohnishi

{"title":"Unicentric Castleman's Disease of Paraspinal Origin Requiring Differentiation From Schwannoma: Case Report.","authors":"Hazuki Fujimoto, Kayoko Okamura, Shunsuke Tauchi, Rei Tsukamoto, Nanami Kida, Miho Ikeda, Yukihisa Hatakeyama, Hisashi Ohnishi","doi":"10.1002/rcr2.70099","DOIUrl":"10.1002/rcr2.70099","url":null,"abstract":"Unicentric Castleman's disease (UCD) typically presents as an asymptomatic tumour in the anterior or middle mediastinum. Occurrence in the paravertebral region is comparatively rare and it requires differentiation from neurogenic tumours by imaging. In our patient, preoperative imaging findings were atypical of schwannoma. Contrast-enhanced MRI of the thoracic region showed a muscle-like mass in contact with the pleura on T1-weighted images. T2-weighted images showed high signal, especially at the margins. Diffusion-weighted images showed diffusion restriction around the limbus, and contrast-enhanced T1-weighted images displayed strong enhancement of the mass. Diagnosis could not be made preoperatively, although UCD was suspected. Thoracoscopic tumour resection was performed for definitive diagnosis and treatment and postoperative diagnosis was hyaline-vascular-type UCD. Diagnosis of neurogenic tumours can be difficult by imaging alone. When imaging findings are atypical, a definitive diagnosis is required, with consideration of the possibility of UCD.","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 1","pages":"e70099"},"PeriodicalIF":0.8,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11756988/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143029399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bronchoscopic-Guided Selective Endobronchial Injection of Methylene Blue Solution for Localising Peripheral Bronchopleural Fistulas During Pleural Debridement in a Post-Lobectomy Patient With Bronchopleural Fistula and Empyema.

IF 0.8

Respirology Case Reports Pub Date : 2025-01-23 eCollection Date: 2025-01-01 DOI: 10.1002/rcr2.70100

Yi Wei, Ke Wang, Honglei Tao, Zhongliang He, Weihua Xu

{"title":"Bronchoscopic-Guided Selective Endobronchial Injection of Methylene Blue Solution for Localising Peripheral Bronchopleural Fistulas During Pleural Debridement in a Post-Lobectomy Patient With Bronchopleural Fistula and Empyema.","authors":"Yi Wei, Ke Wang, Honglei Tao, Zhongliang He, Weihua Xu","doi":"10.1002/rcr2.70100","DOIUrl":"10.1002/rcr2.70100","url":null,"abstract":"The bronchopleural fistula (BPF) is a pathological passageway between the bronchus and the pleural cavity. Diagnosing and localising BPF can be challenging, and the traditional retrograde methylene blue (MB) perfusion method may fail to identify multifocal BPFs. This article reports a novel method for locating multifocal BPFs in patients undergoing concurrent empyema debridement. Initially, selective endobronchial injection of MB solution is performed under bronchoscopic guidance. Subsequently, the thoracic surgeon determines the location of BPFs as the MB solution flows into the pleural cavity. This process of injecting MB within the bronchus is repeated to locate any additional BPFs until no new ones are found. We report a case where this new method was used to identify multifocal BPFs, ultimately diagnosing three BPFs' presence. Following treatment with bronchopleural fistula occlusion, no recurrence of BPFs was observed during the follow-up period.","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 1","pages":"e70100"},"PeriodicalIF":0.8,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11754961/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143030030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Primary tracheo-bronchial adenoid cystic carcinoma: A surgical series with literature review.

IF 0.8

Respirology Case Reports Pub Date : 2025-01-22 eCollection Date: 2025-01-01 DOI: 10.1002/rcr2.70062

Kaouther Ben Amara, Imen Bouassida, Rahma Ayadi, Mariem Affes, Amina Abdelkbir, Mahdi Abdennadher, Salma Ben Othmen, Ayda Ayadi-Kaddour, Hazem Zribi, Adel Marghli

{"title":"Primary tracheo-bronchial adenoid cystic carcinoma: A surgical series with literature review.","authors":"Kaouther Ben Amara, Imen Bouassida, Rahma Ayadi, Mariem Affes, Amina Abdelkbir, Mahdi Abdennadher, Salma Ben Othmen, Ayda Ayadi-Kaddour, Hazem Zribi, Adel Marghli","doi":"10.1002/rcr2.70062","DOIUrl":"10.1002/rcr2.70062","url":null,"abstract":"Tracheo-bronchial adenoid cystic carcinoma (TBACC) is a rare disease. Its treatment is mainly surgical. We herein describe the clinical and para-clinical varieties of TBACC as well as their surgical treatment and prognosis. We conducted a retrospective study of eight patients operated on between 1994 and 2022 and whose definitive pathological examination concluded with primary TBACC. There were three men and five women with an average age of 44 years. The bronchoscopy found a budding formation reducing the tracheal lumen at the cervical (two cases), middle (two case) and distal trachea and carina (four cases). Bronchial anastomosis resection and sleeve pneumonectomy were the most common procedures. Surgical resections R0 were achieved in five patients. Surgery followed by adjuvant radiotherapy was performed in two patients with incomplete surgical resection R1. The overall survival for all patients with primary ACC was 72% at 5 years. TBACC is a rare and low-to-moderate grade malignant tumour. The choice of the surgical procedure and the appropriate approach is challenging to obtain a promising prognosis.","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 1","pages":"e70062"},"PeriodicalIF":0.8,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11753813/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143025101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Interstitial pneumonia due to Japanese spotted fever.

IF 0.8

Respirology Case Reports Pub Date : 2025-01-17 eCollection Date: 2025-01-01 DOI: 10.1002/rcr2.70089

Katsunori Arai, Hirokazu Tokuyasu, Tatsuya Konishi, Toshiyuki Tatsukawa, Kenichi Takeda, Akira Yamasaki

引用次数: 0