{"title":"低PD-L1非小细胞肺癌双ICI联合化疗的显著代谢反应","authors":"Toshikazu Kumasa, Akina Nigi, Keisuke Iwamoto, Hidetoshi Itani, Shigeto Kondou","doi":"10.1002/rcr2.70150","DOIUrl":null,"url":null,"abstract":"<p><p>Despite low PD-L1 (Programmed Death-ligand 1) expression, this patient exhibited a dramatic positron emission tomography-computed tomography response to dual immune checkpoint inhibitors with chemotherapy. This case highlights the potential benefits of combination therapy beyond traditional PD-L1-based treatment selection.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 3","pages":"e70150"},"PeriodicalIF":0.8000,"publicationDate":"2025-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11911389/pdf/","citationCount":"0","resultStr":"{\"title\":\"Dramatic Metabolic Response to Dual ICI With Chemotherapy in Low PD-L1 NSCLC Case.\",\"authors\":\"Toshikazu Kumasa, Akina Nigi, Keisuke Iwamoto, Hidetoshi Itani, Shigeto Kondou\",\"doi\":\"10.1002/rcr2.70150\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Despite low PD-L1 (Programmed Death-ligand 1) expression, this patient exhibited a dramatic positron emission tomography-computed tomography response to dual immune checkpoint inhibitors with chemotherapy. This case highlights the potential benefits of combination therapy beyond traditional PD-L1-based treatment selection.</p>\",\"PeriodicalId\":45846,\"journal\":{\"name\":\"Respirology Case Reports\",\"volume\":\"13 3\",\"pages\":\"e70150\"},\"PeriodicalIF\":0.8000,\"publicationDate\":\"2025-03-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11911389/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Respirology Case Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1002/rcr2.70150\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/3/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q4\",\"JCRName\":\"RESPIRATORY SYSTEM\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Respirology Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1002/rcr2.70150","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/3/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"RESPIRATORY SYSTEM","Score":null,"Total":0}
Dramatic Metabolic Response to Dual ICI With Chemotherapy in Low PD-L1 NSCLC Case.
Despite low PD-L1 (Programmed Death-ligand 1) expression, this patient exhibited a dramatic positron emission tomography-computed tomography response to dual immune checkpoint inhibitors with chemotherapy. This case highlights the potential benefits of combination therapy beyond traditional PD-L1-based treatment selection.
期刊介绍:
Respirology Case Reports is an open-access online journal dedicated to the publication of original clinical case reports, case series, clinical images and clinical videos in all fields of respiratory medicine. The Journal encourages the international exchange between clinicians and researchers of experiences in diagnosing and treating uncommon diseases or diseases with unusual presentations. All manuscripts are peer-reviewed through a streamlined process that aims at providing a rapid turnaround time from submission to publication.