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Utilizing medical thoracoscopy for the diagnosis of B-cell lymphoma presenting with pleural effusion: A case series. 利用内科胸腔镜诊断伴有胸腔积液的 B 细胞淋巴瘤：病例系列。
IF 0.8
Respirology Case Reports Pub Date : 2024-11-19 eCollection Date: 2024-11-01 DOI: 10.1002/rcr2.70061
Nai-Chien Huan, Khai Lip Ng, Larry Ellee Nyanti, Jing Yi Khaw, Jiun Hang Lee, Nur Husna Mohd Aminudin, Dahziela Yunus, Nusaibah Azman, Maryam Ahmad Sharifuddin, Hema Yamini Ramarmuty, Kunji Kannan Sivaraman Kannan
{"title":"Utilizing medical thoracoscopy for the diagnosis of B-cell lymphoma presenting with pleural effusion: A case series.","authors":"Nai-Chien Huan, Khai Lip Ng, Larry Ellee Nyanti, Jing Yi Khaw, Jiun Hang Lee, Nur Husna Mohd Aminudin, Dahziela Yunus, Nusaibah Azman, Maryam Ahmad Sharifuddin, Hema Yamini Ramarmuty, Kunji Kannan Sivaraman Kannan","doi":"10.1002/rcr2.70061","DOIUrl":"10.1002/rcr2.70061","url":null,"abstract":"<p><p>A third of patients with non-Hodgkin's lymphoma (NHL) develop pleural effusion during the disease course for various reasons. In most cases, lymphoma-related pleural effusion is a manifestation of widespread systemic disease, signifying a high tumour burden and therefore, a poorer prognosis. On the other hand, primary pleural lymphomas (PPLs) exhibit exclusive or dominant involvement of serous cavities, without detectable solid tumour masses. PPL is an uncommon disease and is of two types: primary effusion lymphoma (PEL) and diffuse large B-cell lymphoma associated with chronic inflammation (DLBCL-CI). PPLs not related to PELs and DLBCL-CIs are exceedingly rare. Herein, we describe four patients with biopsy proven B-cell NHL. One had no extra-pleural involvement at the time of diagnosis, indicating PPL. In all cases, histopathological examination of pleural biopsies obtained via medical thoracoscopy (MT) were crucial in clinching the final diagnosis. Clinicians are alerted to the potential relationship between exudative effusion and NHL as well as the role of MT in the diagnosis of B-cell NHL.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"12 11","pages":"e70061"},"PeriodicalIF":0.8,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11574453/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142677194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An incidental finding of a pleural based schwannoma. 偶然发现的胸膜分裂瘤。
IF 0.8
Respirology Case Reports Pub Date : 2024-11-18 eCollection Date: 2024-11-01 DOI: 10.1002/rcr2.70066
William Griffin, Nina Mac Auley Srinivasan, Aurelie Fabre, David Healy
{"title":"An incidental finding of a pleural based schwannoma.","authors":"William Griffin, Nina Mac Auley Srinivasan, Aurelie Fabre, David Healy","doi":"10.1002/rcr2.70066","DOIUrl":"10.1002/rcr2.70066","url":null,"abstract":"<p><p>A man in his 40s was incidentally found to have a large right sided apical pleural based mass on imaging. This was further investigated with a CT-guided biopsy. Histological and immunohistochemical analysis of the tissue revealed a diagnosis of a Schwannoma: a rare, slow-growing benign nerve sheath tumour. Only a handful of pleural based Schwannomas have been documented in the literature. They account for about 0.2% of lung tumours. The patient was referred to cardiothoracic surgery who advised surgical resection of the mass, which he is awaiting. Here, we report a rare case of a pleural based Schwannoma which was diagnosed incidentally on chest x-ray.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"12 11","pages":"e70066"},"PeriodicalIF":0.8,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11570798/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142668828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Superimposed pleural infection in cirrhotic chylothorax. 肝硬化乳糜胸叠加胸膜感染。
IF 0.8
Respirology Case Reports Pub Date : 2024-11-18 eCollection Date: 2024-11-01 DOI: 10.1002/rcr2.70065
Ken Ka Pang Chan, Jason Siu Hang Wong, Wing Ho Yip
{"title":"Superimposed pleural infection in cirrhotic chylothorax.","authors":"Ken Ka Pang Chan, Jason Siu Hang Wong, Wing Ho Yip","doi":"10.1002/rcr2.70065","DOIUrl":"10.1002/rcr2.70065","url":null,"abstract":"<p><p>Chylothorax contains an abundant amount of immunoglobulins and white blood cells, leading to the belief that superimposed pleural infection is unlikely. We report two cases of biochemically confirmed chylothorax due to cirrhosis, complicated by superimposed pleural infection following repeated pleural interventions. These findings highlight the potential for superimposed infection in chylothorax and challenge the belief in the bacteriostatic effect of chyle. Clinical vigilance is essential to consider this possibility if features of infection arise during the management of chylothorax.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"12 11","pages":"e70065"},"PeriodicalIF":0.8,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11570799/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142668834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Plastic bronchitis in an adult. 成人塑料支气管炎
IF 0.8
Respirology Case Reports Pub Date : 2024-11-18 eCollection Date: 2024-11-01 DOI: 10.1002/rcr2.70063
Harshana Bandara, Michael D Davis, Stephen J Fowler
{"title":"Plastic bronchitis in an adult.","authors":"Harshana Bandara, Michael D Davis, Stephen J Fowler","doi":"10.1002/rcr2.70063","DOIUrl":"10.1002/rcr2.70063","url":null,"abstract":"<p><p>Plastic bronchitis is rare in adult pulmonology and has a wide range of aetiology. Cast analysis is key in narrowing down the differential diagnosis of plastic bronchitis. If suspected of having lymphocytic PB, complete imaging to evaluate thoracic lymphatics is important to find out the potential causes for PB.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"12 11","pages":"e70063"},"PeriodicalIF":0.8,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11574107/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142677193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pulmonary metastasis of giant cell tumour of tibia. 胫骨巨细胞瘤肺转移。
IF 0.8
Respirology Case Reports Pub Date : 2024-11-12 eCollection Date: 2024-11-01 DOI: 10.1002/rcr2.70060
Arshia Batool, Qura-Tul Ain, Allahdad Khan, Humaira Siddique, Muhammad Islam, Aseel Kamal
{"title":"Pulmonary metastasis of giant cell tumour of tibia.","authors":"Arshia Batool, Qura-Tul Ain, Allahdad Khan, Humaira Siddique, Muhammad Islam, Aseel Kamal","doi":"10.1002/rcr2.70060","DOIUrl":"https://doi.org/10.1002/rcr2.70060","url":null,"abstract":"<p><p>Giant cell tumour of the tibia with pulmonary metastasis is very rare and the malignancy usually appears several years after the initial lesion. Imaging at the earliest instance is highly beneficial since surgical resection to remove the metastases raises survival rates; therefore, relentless follow-up in GCT is vital.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"12 11","pages":"e70060"},"PeriodicalIF":0.8,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11555295/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142630018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Successful treatment of a persistent air leak with an endobronchial valve in a 17-year-old patient with necrotizing pneumonia. 用支气管内瓣膜成功治疗一名 17 岁坏死性肺炎患者的持续性漏气。
IF 0.8
Respirology Case Reports Pub Date : 2024-11-06 eCollection Date: 2024-11-01 DOI: 10.1002/rcr2.70053
Nina M Janssen, Rein Posthuma, Sophie Kienhorst, Michiel A G E Bannier, Ulrich C Lalji, Frits M E Franssen, Roy T M Sprooten
{"title":"Successful treatment of a persistent air leak with an endobronchial valve in a 17-year-old patient with necrotizing pneumonia.","authors":"Nina M Janssen, Rein Posthuma, Sophie Kienhorst, Michiel A G E Bannier, Ulrich C Lalji, Frits M E Franssen, Roy T M Sprooten","doi":"10.1002/rcr2.70053","DOIUrl":"10.1002/rcr2.70053","url":null,"abstract":"<p><p>Pleural empyema is a severe condition associated with high morbidity and mortality. Treatment usually consists of pleural drainage with chest tube or surgery, in combination with antimicrobial treatment. Severe pneumonia can evolve in a necrotizing pneumonia, given a higher susceptibility to the occurrence of bronchopleural fistulas with persistent air leaks. This complicates recovery, and surgery may not always be the optimal treatment. We present a case involving a 17-year-old female patient who experienced a post-operative persistent air leak due to necrotizing pneumonia after video-assisted thoracic surgery decortication for empyema, which was successfully treated using an endobronchial valve. After 6 months the valve was removed without complications. Follow-up imaging and lung function revealed a limited area of atelectasis and minimal pleural thickening with normal lung volumes.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"12 11","pages":"e70053"},"PeriodicalIF":0.8,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11540447/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142590971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Watchful waiting in laryngo-tracheobronchial amyloid: A case report. 喉气管支气管淀粉样变性的观察等待：病例报告
IF 0.8
Respirology Case Reports Pub Date : 2024-11-03 eCollection Date: 2024-11-01 DOI: 10.1002/rcr2.70058
Dylan Beinart, Siaw Ming Chai, Olivia Walsh, Sanjay Ramakrishnan, John Blakey
{"title":"Watchful waiting in laryngo-tracheobronchial amyloid: A case report.","authors":"Dylan Beinart, Siaw Ming Chai, Olivia Walsh, Sanjay Ramakrishnan, John Blakey","doi":"10.1002/rcr2.70058","DOIUrl":"10.1002/rcr2.70058","url":null,"abstract":"<p><p>We report the long term follow up of a now 66-year-old male with laryngo-tracheobronchial amyloidosis. The patient initially presented with dysphonia and dyspnoea. He was diagnosed with laryngeal reflux and asthma. Seven years later, the patient underwent cross sectional thoracic imaging showing diffuse thickening of the distal trachea and proximal main bronchi. The patient's FEV1 and FVC remained stable over 13 years and no intervention was required.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"12 11","pages":"e70058"},"PeriodicalIF":0.8,"publicationDate":"2024-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11532455/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142577023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Imaging of acute dissemination of tuberculosis caused by alveolar lavage surgery in endobronchial tuberculosis characterized by caseous necrosis. 支气管内膜结核病肺泡灌洗手术引起的结核病急性播散的影像学表现，其特点是病例性坏死。
IF 0.8
Respirology Case Reports Pub Date : 2024-10-30 eCollection Date: 2024-11-01 DOI: 10.1002/rcr2.70059
Yunjie Cui, Bo Wang, Cuiping Yang
{"title":"Imaging of acute dissemination of tuberculosis caused by alveolar lavage surgery in endobronchial tuberculosis characterized by caseous necrosis.","authors":"Yunjie Cui, Bo Wang, Cuiping Yang","doi":"10.1002/rcr2.70059","DOIUrl":"10.1002/rcr2.70059","url":null,"abstract":"<p><p>Large amount of caseating overlying on bronchus were detected under bronchoscopy in our case. Bronchoalveolar lavage is a major method for diagnosing tuberculosis (TB). TB dissemination caused by bronchoalveolar lavage is very rare. In this case, the patient developed fever after bronchoalveolar lavage and CT confirmed acute dissemination. This might be related to caseating EBTB.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"12 11","pages":"e70059"},"PeriodicalIF":0.8,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11522607/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142548199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synchronous bilateral typical pulmonary carcinoid tumours diagnosed by robotic navigation bronchoscopy: A unique case. 通过机器人导航支气管镜诊断出同步双侧典型肺类癌：一个独特的病例。
IF 0.8
Respirology Case Reports Pub Date : 2024-10-30 eCollection Date: 2024-11-01 DOI: 10.1002/rcr2.70055
Menna Megahed, Roozbeh Sharif, Yazan Abdeen
{"title":"Synchronous bilateral typical pulmonary carcinoid tumours diagnosed by robotic navigation bronchoscopy: A unique case.","authors":"Menna Megahed, Roozbeh Sharif, Yazan Abdeen","doi":"10.1002/rcr2.70055","DOIUrl":"10.1002/rcr2.70055","url":null,"abstract":"<p><p>Pulmonary carcinoids are uncommon malignant neoplasms, believed to derive from specialized neuroendocrine cells known as Kulchitsky cells. We evaluated a 69-year-old female presenting symptoms consistent with carcinoid syndrome, such as intermittent flushing and diarrhoea, along with complaints of shortness of breath and cough. Imaging revealed bilateral lung nodules, confirmed by biopsy to be carcinoid tumours. The treatment of choice for carcinoid tumours is complete surgical resection. Nonetheless, individualized management plans are crafted based on the tumour's location and the patient's respiratory function as these present challenges to anatomical resection of tumours.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"12 11","pages":"e70055"},"PeriodicalIF":0.8,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11522608/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142548201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Novel CYCLIN-O pathogenic variants in a patient presenting with bronchiectasis secondary to reduced generation of multiple motile cilia. 一名支气管扩张症患者因多种运动纤毛生成减少而出现的新型 CYCLIN-O 致病变体。
IF 0.8
Respirology Case Reports Pub Date : 2024-10-29 eCollection Date: 2024-11-01 DOI: 10.1002/rcr2.70057
Kim Hoong Yap, Albert Yick Hou Lim, Biju Thomas, Carine Bonnard, Emmanuelle Szenker-Ravi, Yan Ling Chong, Sudipto Roy, Bruno Reversade
{"title":"Novel CYCLIN-O pathogenic variants in a patient presenting with bronchiectasis secondary to reduced generation of multiple motile cilia.","authors":"Kim Hoong Yap, Albert Yick Hou Lim, Biju Thomas, Carine Bonnard, Emmanuelle Szenker-Ravi, Yan Ling Chong, Sudipto Roy, Bruno Reversade","doi":"10.1002/rcr2.70057","DOIUrl":"10.1002/rcr2.70057","url":null,"abstract":"<p><p>Reduced generation of multiple motile cilia (RGMC) represents a rare variant of Primary Ciliary Dyskinesia (PCD), associated with <i>CYCLIN-O (CCNO)</i> mutations. We report a novel compound mutation in the <i>CCNO</i> gene in an adult Chinese Singaporean exhibiting chronic productive cough since childhood and recurrent sino-pulmonary infections. Low nasal nitric oxide and bronchiectasis suggests PCD. Bronchoscopy for epithelial and nasal brushings for ciliary studies were repeated after adequate treatment of lower respiratory tract infections. Demonstration of oligo-cilia via transmission electron microscopy, and detection of <i>CCNO</i> mutation through genetic analysis were utilized to diagnose RGMC. Repeated courses of antibiotics including nebulised antibiotics were used to treat recurrent infections and exacerbations. Airway clearance techniques, immunizations and collaboration with otorhinolaryngologist form part of the long-term management. Heightened clinical suspicion and adherence to established diagnostic algorithms are essential for timely recognition of this entity.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"12 11","pages":"e70057"},"PeriodicalIF":0.8,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11519382/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142548200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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