Respirology Case ReportsPub Date : 2026-07-27eCollection Date: 2026-07-01DOI: 10.1002/rcr2.70672
Stefani Larasati, Awalia
{"title":"A Rare Association of Interstitial Lung Disease in Ankylosing Spondylitis: A Case Report and Review of Early Detection and Multidisciplinary Management.","authors":"Stefani Larasati, Awalia","doi":"10.1002/rcr2.70672","DOIUrl":"10.1002/rcr2.70672","url":null,"abstract":"<p><p>Ankylosing spondylitis (AS) is a chronic inflammatory disorder of the axial skeleton, occasionally complicated by uncommon but increasingly recognized pulmonary involvement such as interstitial lung disease (ILD). We report a 35-year-old woman with a year-long history of inflammatory back pain and peripheral arthritis who fulfilled clinical and radiologic criteria for AS. Despite partial response to cDMARDs, she developed a productive cough. High-resolution CT revealed right upper-lobe ground-glass opacities consistent with early cellular ILD, supported by spirometry showing a moderate restrictive defect and negative autoimmune serology excluding overlapping connective tissue diseases. Conservative pulmonary monitoring and escalation to secukinumab resulted in marked improvement in both musculoskeletal and respiratory symptoms. This case highlights clinically under-recognized pulmonary involvement in AS, including early inflammatory (cellular) ILD, emphasizing diagnostic challenges and the importance of timely imaging and multidisciplinary management.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"14 7","pages":"e70672"},"PeriodicalIF":0.7,"publicationDate":"2026-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13403755/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148680392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Respirology Case ReportsPub Date : 2026-07-24eCollection Date: 2026-07-01DOI: 10.1002/rcr2.70695
Dua Nori, Suha Nori, Dania A Ashoor, Lana M Dweekat, Reem Shihab
{"title":"Hemoptysis Secondary to Right Pulmonary Artery Aneurysm in Behçet's Disease: A Case Report and Literature Review.","authors":"Dua Nori, Suha Nori, Dania A Ashoor, Lana M Dweekat, Reem Shihab","doi":"10.1002/rcr2.70695","DOIUrl":"10.1002/rcr2.70695","url":null,"abstract":"<p><p>Behçet's disease is a systemic inflammatory vasculitis that can involve vessels of any size, with pulmonary artery aneurysms representing a rare but potentially fatal complication. Hemoptysis is the most common presentation and may recur despite medical or interventional therapy. We report a 38-year-old man with Behçet's disease and a history of right pulmonary artery aneurysm treated with endovascular coil embolization and ongoing immunosuppressive therapy, who presented with recurrent hemoptysis. He was managed with supportive care, high-dose corticosteroid pulse therapy, and continuation of biologic immunosuppressants. Hemoptysis resolved, and follow-up imaging was planned to monitor disease progression. Pulmonary artery involvement in BD demands a patient-specific, integrated management strategy combining medical therapy, interventional procedures, and careful monitoring to prevent fatal complications and ensure long-term disease control.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"14 7","pages":"e70695"},"PeriodicalIF":0.7,"publicationDate":"2026-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13400455/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148593996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Respirology Case ReportsPub Date : 2026-07-22eCollection Date: 2026-07-01DOI: 10.1002/rcr2.70693
Hidenori Takahashi, Kota Taguchi, Mio Toyama-Kousaka, Shinichiro Ota, Masaharu Shinkai
{"title":"Mediastinal Extrapleural Air Mimicking a Bulla in a Non-Expandable Lung.","authors":"Hidenori Takahashi, Kota Taguchi, Mio Toyama-Kousaka, Shinichiro Ota, Masaharu Shinkai","doi":"10.1002/rcr2.70693","DOIUrl":"10.1002/rcr2.70693","url":null,"abstract":"<p><p>In a patient with pleuroparenchymal fibroelastosis and a non-expandable lung, CT and three-dimensional rendering showed a bulla-like mediastinal air pocket that regressed on follow-up imaging and lacked an autopsy correlate, supporting intrathoracic extrapleural air rather than a true pulmonary bulla.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"14 7","pages":"e70693"},"PeriodicalIF":0.7,"publicationDate":"2026-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13391238/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148580596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Respirology Case ReportsPub Date : 2026-07-20eCollection Date: 2026-07-01DOI: 10.1002/rcr2.70691
Abdullah S Almawi, Mohammed S Almasri, Fahad A Almejrad, Mohammed N Almusaad, Maher Alanazi
{"title":"Endovascular Coil Embolization of Ruptured Idiopathic Multiple Bilateral Pulmonary Artery Aneurysms: A Case Report.","authors":"Abdullah S Almawi, Mohammed S Almasri, Fahad A Almejrad, Mohammed N Almusaad, Maher Alanazi","doi":"10.1002/rcr2.70691","DOIUrl":"10.1002/rcr2.70691","url":null,"abstract":"<p><p>Pulmonary artery aneurysms are rare vascular abnormalities with a diverse etiologies, including infection, vasculitis, trauma, and congenital disorders. Untreated aneurysms carry a substantial risk of rupture and mortality, particularly in symptomatic individuals. We report a case of a 24-year-old man who presented with hemoptysis and progressive shortness of breath over 1 month. Computed tomography angiography revealed multiple bilateral saccular aneurysms of the pulmonary arteries, one of which was ruptured. Subsequently, urgent endovascular embolization of all aneurysms using detachable coils was performed. The procedure was technically successful and uneventful, resulting in marked clinical improvement. This case illustrates a rare presentation of idiopathic bilateral pulmonary artery aneurysms with concurrent rupture and supports endovascular embolization as a safe and effective treatment option in such cases.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"14 7","pages":"e70691"},"PeriodicalIF":0.7,"publicationDate":"2026-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13384772/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148550854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Rare Case of Scrofuloderma Presenting as Recurrent Tuberculosis in a Young Patient.","authors":"Yoshihiro Okada, Asuka Okada, Shin Miyagawa, Ami Arimoto, Taisei Furumuro, Masanori Izuka, Yuma Watabe, Izumi Sato, Yusuke Inui, Masahide Ueda, Takahiro Ibaraki, Hideaki Takenaka, Sumito Choh","doi":"10.1002/rcr2.70694","DOIUrl":"10.1002/rcr2.70694","url":null,"abstract":"<p><p>A 23-year-old Indonesian man was referred to our institution due to a skin ulcer with white exudate on the right chest wall. He had undergone treatment for pulmonary tuberculosis (TB) in Indonesia 3 years prior to the consultation. Chest ultrasonography and computed tomography revealed multiple intercostal abscesses and a thickened right pleura with calcification. Histological findings from a skin biopsy of the ulcer and a positive polymerase chain reaction for <i>Mycobacterium tuberculosis</i> in the exudate indicated the involvement of TB. Based on these findings, the patient was diagnosed with scrofuloderma and multiple intercostal abscesses. Recurrent TB may result from either the regrowth of residual strains or reinfection with a different strain. This report highlights that recurrent TB can manifest as scrofuloderma through contiguous spread from underlying intercostal abscesses. In cases of skin ulcers with an unclear aetiology, thorough histopathological and bacteriological assessments facilitate a prompt and accurate diagnosis.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"14 7","pages":"e70694"},"PeriodicalIF":0.7,"publicationDate":"2026-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13384745/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148608469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The First Documented Case of Congenital Drug-Resistant Tuberculosis in Indonesia: A Case Report.","authors":"Cynthia Centauri, Srisadono Fauzi Adiprabowo, Putri Maharani Tristanita Marsubrin, Irandi Putra Pratomo","doi":"10.1002/rcr2.70680","DOIUrl":"10.1002/rcr2.70680","url":null,"abstract":"<p><p>Congenital drug-resistant tuberculosis (DR-TB) is a rare condition with no standardized treatment. Congenital TB itself is a life-threatening condition. The clinical manifestations can be nonspecific, particularly in preterm infants, which can further reduce diagnostic awareness. We report a case of a 32-week preterm baby with rifampicin-resistant TB. She was born with respiratory distress and early-onset jaundice, initially suspected of sepsis and admitted to the NICU. The infant initially showed clinical improvement at 3 days of life, but at 23 days of life, the clinical condition worsened despite a sterile blood culture. The mother was subsequently diagnosed with miliary TB with rifampicin-resistant Xpert sputum. The infant's gastric lavage Xpert MTB/RIF confirmed rifampicin-resistant TB. At 32 days of life, she received a five-drug regimen, including bedaquiline. She completed 12 months of treatment with a favourable outcome. This case highlights the challenges of early recognition and treatment selection in congenital DR-TB.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"14 7","pages":"e70680"},"PeriodicalIF":0.7,"publicationDate":"2026-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13385517/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148550834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"<i>Nocardia cyriacigeorgica</i> Identified by Bronchial Washing During Evaluation of Radiologic Progression in a Patient With Prior Nontuberculous Mycobacterial Diseases.","authors":"Hidenori Takahashi, Kanako Furukawa, Yugo Satake, Natsuko Nakano, Shinichiro Ota, Masaharu Shinkai","doi":"10.1002/rcr2.70654","DOIUrl":"10.1002/rcr2.70654","url":null,"abstract":"<p><p>Pulmonary nocardiosis may occur in immunocompetent patients with structural lung disease and may resemble the progression of nontuberculous mycobacterial pulmonary disease. We report an 81-year-old immunocompetent woman with chronic bronchiectasis and prior <i>Mycobacterium kansasii</i>, <i>M. intracellulare</i>, and <i>M. abscessus</i> infections. Despite persistently negative sputum mycobacterial cultures, chest computed tomography (CT) revealed progressive nodular bronchiectatic changes. Bronchial washing from the right B5 bronchus yielded <i>Nocardia cyriacigeorgica</i>; mycobacterial studies were negative. Trimethoprim-sulfamethoxazole was stopped shortly after initiation because of drug eruption, and minocycline monotherapy led to transient symptomatic and radiologic improvement. However, follow-up CT at 6 months revealed radiologic progression. Repeat bronchoscopy was culture-negative, but bronchial washing cytology revealed filamentous organisms suggestive of persistent nocardial infection. Minocycline monotherapy was continued for 12 months. Chest CT at 12 months revealed new contralateral left upper lobe bronchocentric abnormalities. This case highlights the importance of bronchial washing and longitudinal reassessment when radiologic progression remains unexplained by sputum evaluation.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"14 7","pages":"e70654"},"PeriodicalIF":0.7,"publicationDate":"2026-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13381721/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148608414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Anomalous Systemic Arterial Supply to the Basal Segment of the Lung Treated With Surgery Versus Transcatheter Embolisation: A Report of Two Cases.","authors":"Hidenori Takahashi, Shinichiro Ota, Yugo Satake, Hiroki Nagamatsu, Ryutaro Hirose, Mio Toyama-Kosaka, Miwa Morikawa, Takashi Makino, Yuta Tajiri, Natsuko Nakano, Masaharu Shinkai","doi":"10.1002/rcr2.70652","DOIUrl":"10.1002/rcr2.70652","url":null,"abstract":"<p><p>Anomalous systemic arterial supply to the basal segment of the lungs (ABLL) is a rare congenital vascular anomaly, and its treatment remains disputed. We report two cases of ABLL that were asymptomatic and managed using different strategies based on infection status and anatomical complexity. A 25-year-old woman presented with a right lower lobe cavitary lesion supplied by an anomalous coeliac artery branch. Due to suspected chronic fungal infection, thoracoscopic right basal segmentectomy was performed, and subsequent pathology and cultures confirmed chronic cavitary aspergillosis. A 33-year-old man presented with an anomalous branch from the descending thoracic aorta supplying the left basal segment. Surgical resection was considered potentially more invasive because of an incomplete fissure and a common left pulmonary vein trunk; therefore, transcatheter embolisation was successfully performed. These cases suggest that treatment selection should be individualised and guided not only by vessel diameter but also by associated infection and anatomical complexity.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"14 7","pages":"e70652"},"PeriodicalIF":0.7,"publicationDate":"2026-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13381719/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148608458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Respirology Case ReportsPub Date : 2026-07-17eCollection Date: 2026-07-01DOI: 10.1002/rcr2.70678
Keisuke Watanabe, Toshiko Kamata, Shigetoshi Yoshida, Tetsuo Sato
{"title":"Drug-Induced Lung Injury Masking Lung Adenocarcinoma.","authors":"Keisuke Watanabe, Toshiko Kamata, Shigetoshi Yoshida, Tetsuo Sato","doi":"10.1002/rcr2.70678","DOIUrl":"10.1002/rcr2.70678","url":null,"abstract":"<p><p>We report a case of lung adenocarcinoma masked by drug-induced lung injury. Lung adenocarcinoma can present with consolidation, known as pneumonic-type lung adenocarcinoma, which mimics inflammatory lung disease. Therefore, careful radiological follow-up should be performed even after apparent resolution of pneumonia.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"14 7","pages":"e70678"},"PeriodicalIF":0.7,"publicationDate":"2026-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13379310/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148498209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Respirology Case ReportsPub Date : 2026-07-15eCollection Date: 2026-07-01DOI: 10.1002/rcr2.70690
Maura Silva, Cristina Mendes, Kátia Diogo, João Silva, Margarete Arrais
{"title":"Laryngotracheobronchitis due to <i>Candida albicans</i> in a Patient Admitted to the Intensive Care Unit: A Case Report.","authors":"Maura Silva, Cristina Mendes, Kátia Diogo, João Silva, Margarete Arrais","doi":"10.1002/rcr2.70690","DOIUrl":"10.1002/rcr2.70690","url":null,"abstract":"<p><p>Several studies have identified <i>Candida albicans</i> as the predominant fungal pathogen involved in respiratory infections. Candida laryngotracheobronchitis is a rare but serious condition, typically observed in immunocompromised patients with predisposing conditions, and its diagnosis poses a challenge due to its nonspecific presentation. We report the case of a 39-year-old woman who was admitted to the Intensive Care Unit for diabetic ketoacidosis associated with severe pneumonia, requiring mechanical ventilation and broad-spectrum antibiotic therapy. She initially responded favourably to treatment; however, 12 h after extubation, she presented with a dry cough, dysphonia and signs of persistent bronchospasm. The findings from bronchofibroscopy and the culture of tracheal and bronchial secretions and washings were consistent with laryngotracheobronchial candidiasis. She was treated with antifungal, resulting in significant clinical improvement and resolution of the endoscopic lesions. Currently, the patient remains stable and is under outpatient follow-up by Pulmonology, Otolaryngology and Endocrinology.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"14 7","pages":"e70690"},"PeriodicalIF":0.7,"publicationDate":"2026-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13372571/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148473348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}