Respirology Case Reports最新文献_第10页

A rare case of a huge malignant pleural mesothelioma presenting in the posterior mediastinum. 一例罕见的后纵隔巨大恶性胸膜间皮瘤。

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Respirology Case Reports Pub Date : 2024-07-09 eCollection Date: 2024-07-01 DOI: 10.1002/rcr2.1429

Yuta Mori, Chihiro Kato, Hideo Yamakawa, Mariko Sugiura, Kensuke Fukumitsu, Satoshi Fukuda, Yoshihiro Kanemitsu, Takehiro Uemura, Tomoko Tajiri, Hirotsugu Ohkubo, Yutaka Ito, Tetsuya Oguri, Takayuki Murase, Akio Niimi

{"title":"A rare case of a huge malignant pleural mesothelioma presenting in the posterior mediastinum.","authors":"Yuta Mori, Chihiro Kato, Hideo Yamakawa, Mariko Sugiura, Kensuke Fukumitsu, Satoshi Fukuda, Yoshihiro Kanemitsu, Takehiro Uemura, Tomoko Tajiri, Hirotsugu Ohkubo, Yutaka Ito, Tetsuya Oguri, Takayuki Murase, Akio Niimi","doi":"10.1002/rcr2.1429","DOIUrl":"10.1002/rcr2.1429","url":null,"abstract":"We report a case of a 69-year-old woman with pleural mesothelioma presenting in the posterior mediastinum with a maximum diameter of 25 cm. She had a chronic cough and a pleural effusion was noted on chest X-ray. The examination of the effusion showed high hyaluronic acid levels, and mesothelioma was suspected. A chest computed tomography scan showed a huge mediastinal mass, which caused rapid progression of respiratory failure and compression of the heart. Sufficient tissue samples could not be obtained before death. The patient died approximately 1 month after the initial visit, and a pathological autopsy was performed. The diagnosis of malignant pleural mesothelioma was made. Malignant pleural mesothelioma with a huge posterior mediastinal mass such as in this case is considerably rare; however, it is a rapidly progressing form of the disease and is reported here as an important differential diagnosis for mediastinal tumours.","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"12 7","pages":"e01429"},"PeriodicalIF":0.8,"publicationDate":"2024-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11231739/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141564802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Treatment with low-dose nintedanib and tacrolimus in patients with progressive fibrosing interstitial lung diseases with anti-ARS antibody-positive dermatomyositis. 用小剂量宁替达尼和他克莫司治疗伴有抗ARS抗体阳性皮肌炎的进展性纤维化间质性肺疾病患者。

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Respirology Case Reports Pub Date : 2024-07-09 eCollection Date: 2024-07-01 DOI: 10.1002/rcr2.1428

Takeshi Kawaguchi, Motohiro Matsuda, Kunihiko Umekita, Taiga Miyazaki

引用次数: 0

Severe lupus pneumonitis: A case of life-saving multimodal therapy with rituximab and corticosteroids. 严重狼疮性肺炎：使用利妥昔单抗和皮质类固醇进行多模式疗法挽救生命的病例。

IF 0.8

Respirology Case Reports Pub Date : 2024-07-03 eCollection Date: 2024-07-01 DOI: 10.1002/rcr2.1426

Amirhossein Aarabi, Stella McGinn

{"title":"Severe lupus pneumonitis: A case of life-saving multimodal therapy with rituximab and corticosteroids.","authors":"Amirhossein Aarabi, Stella McGinn","doi":"10.1002/rcr2.1426","DOIUrl":"10.1002/rcr2.1426","url":null,"abstract":"Severe lupus pneumonitis is a rare and life-threatening complication of systemic lupus erythematosus (SLE), characterized by its rapid progression and high mortality rate. This case report describes the clinical trajectory and therapeutic management of a young Aboriginal female with established lupus nephritis who developed severe lupus pneumonitis. Despite her stable renal condition under long-term immunosuppressive treatment, she experienced acute respiratory distress, leading to her admission to the intensive care unit and subsequent mechanical ventilation. The diagnostic process was complicated by the difficulty in obtaining tissue biopsies, necessitating reliance on clinical judgement and radiological evidence to formulate a diagnosis. The patient was treated with pulsed intravenous methylprednisolone followed by rituximab infusions, resulting in significant clinical and radiological improvement. This case highlights the importance of early and intensive immunosuppressive therapy in the management of severe lupus pneumonitis and underscores the utility of a multidisciplinary approach in overcoming diagnostic ambiguities. Furthermore, it contributes to the growing body of evidence supporting the efficacy of rituximab in severe lupus pneumonitis cases, offering insights into potential therapeutic avenues when conventional management strategies are inadequate or unsuitable.","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"12 7","pages":"e01426"},"PeriodicalIF":0.8,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11221880/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141499304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Allergic bronchopulmonary aspergillosis with metachronous isolation of three distinct Aspergillus species. 过敏性支气管肺曲霉菌病，同时分离出三种不同的曲霉菌。

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Respirology Case Reports Pub Date : 2024-07-03 eCollection Date: 2024-07-01 DOI: 10.1002/rcr2.1423

Yosuke Sasahara, Kentaro Akata, Kei Yamasaki, Takeshi Orihashi, Kazuhiro Yatera

{"title":"Allergic bronchopulmonary aspergillosis with metachronous isolation of three distinct Aspergillus species.","authors":"Yosuke Sasahara, Kentaro Akata, Kei Yamasaki, Takeshi Orihashi, Kazuhiro Yatera","doi":"10.1002/rcr2.1423","DOIUrl":"10.1002/rcr2.1423","url":null,"abstract":"Allergic bronchopulmonary aspergillosis (ABPA) is an inflammatory disease induced by exaggerated immune responses to Aspergillus species. Although ABPA has a high recurrence (48%), its instances with sequential isolation of distinct Aspergillus species are sporadic. Only one case report has documented the metachronous isolation of Aspergillus fumigatus and Aspergillus flavus. However, no reported cases of metachronous isolation involving three distinct Aspergillus species exist. Herein, we report a novel case of a 47-year-old Japanese man with sequential metachronous isolation of A. flavus, A. terreus, and A. fumigatus. Initially presenting with symptoms of productive cough and pulmonary infiltration, the patient experienced two relapses following treatment with oral prednisolone. Adjustments in therapy, including voriconazole and a tailored corticosteroid regimen, resulted in significant improvement without relapse for over 6 months. This case report highlights the challenges and successful management of ABPA involving multiple Aspergillus species.","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"12 7","pages":"e01423"},"PeriodicalIF":0.8,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11221881/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141500161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Farewell John Wrightson DPhil MA FRCP 告别约翰-赖特森博士硕士 FRCP

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Respirology Case Reports Pub Date : 2024-07-01 DOI: 10.1002/rcr2.1425

Keiko Kan‐o

引用次数: 0

A drastic post operative course after the resection of primary pulmonary choriocarcinoma in a male. 一名男性原发性肺绒毛膜癌切除术后病情急剧恶化。

IF 0.8

Respirology Case Reports Pub Date : 2024-07-01 DOI: 10.1002/rcr2.1400

Makoto Takahama

引用次数: 0

A case of treatment for pulmonary infection caused by multidrug-resistant Acinetobacter baumannii. 一例耐多药鲍曼不动杆菌引起的肺部感染治疗病例。

IF 0.8

Respirology Case Reports Pub Date : 2024-07-01 DOI: 10.1002/rcr2.1420

Chenxia Guo, Shaohua Xu, Wei Yan

引用次数: 0

A grand mimicker of pulmonary malignancy: The massive mediastinal intercostal nerve tumour. 肺部恶性肿瘤的巨大假象：巨大纵隔肋间神经瘤

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Respirology Case Reports Pub Date : 2024-06-27 eCollection Date: 2024-07-01 DOI: 10.1002/rcr2.1422

Syed H Haq, Claire Friederick, David Eapen, Sidra Shah, Hoshimjon Begmatov, F N U Sandesh, Sreenivasa Chanamolu

引用次数: 0

Meigs syndrome presenting with recurrent unilateral pleural effusion. 梅格斯综合征表现为复发性单侧胸腔积液。

IF 0.8

Respirology Case Reports Pub Date : 2024-06-26 eCollection Date: 2024-07-01 DOI: 10.1002/rcr2.1421

Boon Hau Ng, Sarah Hani Johari How, Nik Nuratiqah Nik Abeed, Hsueh Jing Low, Rose Azzlinda Osman, Andrea Ban Yu-Lin

{"title":"Meigs syndrome presenting with recurrent unilateral pleural effusion.","authors":"Boon Hau Ng, Sarah Hani Johari How, Nik Nuratiqah Nik Abeed, Hsueh Jing Low, Rose Azzlinda Osman, Andrea Ban Yu-Lin","doi":"10.1002/rcr2.1421","DOIUrl":"https://doi.org/10.1002/rcr2.1421","url":null,"abstract":"Pelvic tumours are a rare cause of pleural effusion. We describe an approach to a case of Meigs syndrome with recurrent unilateral pleural effusion. A woman in her 60s' presented with recurrent right-sided pleural effusion, leading to cough and shortness of breath. Thoracentesis yielded exudative pleural fluid with cytology negative for malignancy. Pleuroscopy revealed inflamed pleura, and pleural biopsy was consistent with inflammatory changes. The patient's cancer antigen 125 level was elevated at 256 U/mL. Given the high suspicion of malignancy, a computed tomography scan of the chest, abdomen, and pelvis was performed and revealed ascites and a large left ovarian and uterine mass. The patient underwent a total abdominal hysterectomy and bilateral salphingo oophorectomy after experiencing three additional episodes of pleural effusion. Histological examination revealed the left ovarian mass to be a cellular fibroma and the uterine masses to be leiomyomata. Following the operation, there was no recurrence of pleural effusion.","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"12 7","pages":"e01421"},"PeriodicalIF":0.8,"publicationDate":"2024-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11208080/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141471486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mesenchymal-epithelial transition factor exon 14 skipping mutation-positive granulocyte colony-stimulating factor-producing lung adenocarcinoma mimicking lung abscess: A case report. 间充质-上皮转化因子第 14 号外显子跳跃突变阳性粒细胞集落刺激因子产生的肺腺癌模拟肺脓肿：病例报告。

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Respirology Case Reports Pub Date : 2024-06-25 eCollection Date: 2024-06-01 DOI: 10.1002/rcr2.1419

Yuka Izumiya, Hidesato Odaka, Toru Kikuchi, Yuri Takita, Takuo Tokairin

{"title":"Mesenchymal-epithelial transition factor exon 14 skipping mutation-positive granulocyte colony-stimulating factor-producing lung adenocarcinoma mimicking lung abscess: A case report.","authors":"Yuka Izumiya, Hidesato Odaka, Toru Kikuchi, Yuri Takita, Takuo Tokairin","doi":"10.1002/rcr2.1419","DOIUrl":"10.1002/rcr2.1419","url":null,"abstract":"Granulocyte colony-stimulating factor (G-CSF)-producing lung tumours are rare, with their imaging features and effective treatments remaining elusive. Similarly, mesenchymal-epithelial transition (MET) exon 14 skipping mutations are also uncommon. Herein, we report a case of G-CSF-producing lung adenocarcinoma positive for a MET exon 14 skipping mutation, mimicking lung abscess. A 61-year-old man presented with cough and high fever. Contrast-enhanced chest computed tomography revealed a mass with a cavity and internal fluid accumulation. The patient initially underwent diagnostic treatment for a lung abscess but was ultimately diagnosed with lung adenocarcinoma positive for a MET exon 14 skipping mutation. Following tepotinib therapy, the primary lesion shrank, and serum G-CSF levels decreased, leading to a diagnosis of G-CSF-producing lung cancer. G-CSF-producing lung tumours can present imaging findings that mimic lung abscesses. Tepotinib therapy may be effective for patients with MET exon 14 skipping mutation, including those with G-CSF-producing lung cancer.","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"12 6","pages":"e01419"},"PeriodicalIF":0.8,"publicationDate":"2024-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11196950/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141452713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0