自体血联合米诺环素胸膜融合术治疗老年合并肺纤维化和肺气肿的顽固性双侧气胸1例。

IF 0.8 Q4 RESPIRATORY SYSTEM

Respirology Case Reports Pub Date : 2025-09-22 eCollection Date: 2025-09-01 DOI:10.1002/rcr2.70358

Eitetsu Koh

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引用次数: 0

摘要

双侧气胸合并肺纤维化和肺气肿（CPFE）的老年患者是罕见的，通常排除手术。我们报告一位86岁的男性CPFE和持续的空气泄漏无反应管引流。经胸管联合胸膜切除术，使用50ml自体血和100mg米诺环素，用50ml生理盐水稀释，间隔3天，两疗程结束。两个月后，发生对侧气胸，并采用相同的方案成功治疗。未观察到手术相关并发症；随访6个月无复发。当手术禁忌时，这种简单的床边方法可能是一种实用的选择。

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Successful Combined Autologous Blood and Minocycline Pleurodesis for Intractable Bilateral Pneumothorax in an Elderly Patient With Combined Pulmonary Fibrosis and Emphysema: A Case Report.

Bilateral pneumothorax in elderly patients with combined pulmonary fibrosis and emphysema (CPFE) is rare and often precludes surgery. We report an 86-year-old man with CPFE and a persistent air leak unresponsive to tube drainage. Combined pleurodesis via the chest tube using 50 mL autologous blood and 100 mg minocycline diluted in 50 mL saline achieved cessation after two sessions 3 days apart. Two months later, contralateral pneumothorax occurred and was successfully treated using the same protocol. No procedure-related complications were observed; no recurrence was seen at 6-month follow-up. This simple bedside approach may be a practical option when surgery is contraindicated.

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来源期刊

Respirology Case Reports RESPIRATORY SYSTEM-

CiteScore

1.40

自引率

0.00%

发文量

178

审稿时长

8 weeks

期刊介绍： Respirology Case Reports is an open-access online journal dedicated to the publication of original clinical case reports, case series, clinical images and clinical videos in all fields of respiratory medicine. The Journal encourages the international exchange between clinicians and researchers of experiences in diagnosing and treating uncommon diseases or diseases with unusual presentations. All manuscripts are peer-reviewed through a streamlined process that aims at providing a rapid turnaround time from submission to publication.