Clinical Neurophysiology Practice最新文献

{"title":"REM parasomnias: Straddling the sleep-wake line","authors":"Jayant N. Acharya, Vinita J. Acharya","doi":"10.1016/j.cnp.2024.01.002","DOIUrl":"10.1016/j.cnp.2024.01.002","url":null,"abstract":"","PeriodicalId":45697,"journal":{"name":"Clinical Neurophysiology Practice","volume":"9 ","pages":"Pages 51-52"},"PeriodicalIF":1.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2467981X24000039/pdfft?md5=90c8ff173712075f56fbe8fb9f775611&pid=1-s2.0-S2467981X24000039-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139456916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spinal lumbar multimodal neurophysiological monitoring in a patient with deep brain Stimulator: A case report","authors":"Daniel San-juan ,&nbsp;Rafael Diaz-Martinez ,&nbsp;Victor Alcocer-Barradas ,&nbsp;Luis Alberto Ortega-Porcayo ,&nbsp;Marcela Amparo Osuna-Zazueta ,&nbsp;Maria Fernanda Tejada-Pineda","doi":"10.1016/j.cnp.2024.10.003","DOIUrl":"10.1016/j.cnp.2024.10.003","url":null,"abstract":"<div><div>Intraoperative neurophysiological monitoring (IONM) is a highly valuable tool in spinal surgery. It allows for real-time evaluation of nervous system function and alerts the surgeon to any warning signs. Among the various techniques used are motor evoked potentials (MEPs) through transcranial electrical stimulation, which involve applying an electrical stimulus to the scalp in the primary motor cortex region and recording it in the corresponding muscles of the corticospinal tract. There are relative contraindications for this technique, such as in patients who have an implantable device. There is no consensus on how to perform this technique in patients with a deep brain stimulator.</div><div>We present the case of a 61-year-old patient with Parkinson’s disease and a deep brain stimulator (DBS), and who underwent spinal surgery for lumbar discopathy. IONM was performed during the procedure using MEPs, necessitating the deactivation of the DBS to protect its function. Upon completion of the surgical procedure, the device was reactivated, confirming its proper function. We demonstrate that this technique can be safe for these patients, weighing the potential risks and benefits. However, it will be necessary to develop specific guidelines for performing these techniques in the future.</div></div>","PeriodicalId":45697,"journal":{"name":"Clinical Neurophysiology Practice","volume":"9 ","pages":"Pages 261-265"},"PeriodicalIF":2.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142571621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A 1-month ketogenic diet in patients with migraine gives a clinical beneficial effect associated with increased latency of somatosensory thalamo-cortical activity","authors":"Chiara Abagnale ,&nbsp;Gabriele Sebastianelli ,&nbsp;Francesco Casillo ,&nbsp;Antonio Di Renzo ,&nbsp;Vincenzo Parisi ,&nbsp;Ettore Cioffi ,&nbsp;Mariano Serrao ,&nbsp;Jean Schoenen ,&nbsp;Gianluca Coppola ,&nbsp;Cherubino Di Lorenzo","doi":"10.1016/j.cnp.2024.11.002","DOIUrl":"10.1016/j.cnp.2024.11.002","url":null,"abstract":"<div><h3>Objective</h3><div>Since the habituation deficit of evoked potentials could be related to abnormal thalamocortical drive, we searched for a modulatory effect of ketogenic diet (KD) on somatosensory-evoked thalamo-cortical activity. KD is effective in preventing migraine. Previous studies showed that KD normalises habituation of somatosensory and visual cortical evoked responses in parallel with a decrease in of migraine attack frequency.</div></div><div><h3>Methods</h3><div>We electrically stimulated the median nerve at the wrist to record somatosensory high-frequency oscillations (HFOs) in twenty patients with episodic migraine with and without aura before and after one month of normo- (n = 9) or hypocaloric KD (n = 11). For pre-synaptic thalamocortical and post-synaptic cortical HFOs, we measured the latency of the negative oscillatory maximum, the intra-burst frequency, the number of negative peaks, and the maximum peak-to-peak amplitude.</div></div><div><h3>Results</h3><div>In the total group of patients, the one-month KD significantly increased the latency of the negative oscillatory maximum in pre-synaptic, i.e. thalamocortical activity (t = 2.70, p = 0.015) and in post-synaptic HFOs, i.e. cortical activity (t = 3.08, p = 0.006). This effect could be attributed to hypo-caloric KD, as it was not found after normo-caloric KD. Other HFO parameters, such as amplitude, duration, or number of oscillations, were not affected.</div></div><div><h3>Conclusions</h3><div>A 1-month hypo-caloric KD is able to delay the propagation of neuronal activity through the thalamo-cortical network. This effect does not seem to be correlated with the therapeutic efficacy of KD, but rather to low-calorie intake.</div></div><div><h3>Significance</h3><div>Our results imply that consuming a restricted amount of calories could alter the balance between central excitation and inhibition in migraine.</div></div>","PeriodicalId":45697,"journal":{"name":"Clinical Neurophysiology Practice","volume":"9 ","pages":"Pages 292-298"},"PeriodicalIF":2.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142698312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Visualization of radial nerve activity at the upper arm using magnetoneurography","authors":"Takeyasu Toyama ,&nbsp;Muneharu Ando ,&nbsp;Masaaki Paku ,&nbsp;Shinji Sato ,&nbsp;Yusuke Yamamoto ,&nbsp;Shinichirou Taniguchi ,&nbsp;Nobuo Kohara ,&nbsp;Takanori Saito","doi":"10.1016/j.cnp.2024.11.001","DOIUrl":"10.1016/j.cnp.2024.11.001","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate the function of the radial nerve in the upper arm using Magnetoneurography (MNG).</div></div><div><h3>Methods</h3><div>Eight asymptomatic male volunteers (age 25–63 years) and one 67-year-old female patient with radial nerve palsy were included. The radial nerve was electrically stimulated in the right wrist, and the evoked magnetic field was recorded using a 132-channel bio-magnetometer system with a superconducting quantum interference device positioned below the upper arm. The measurements were divided into distal and proximal sessions because of the extensive range of the nerve.</div></div><div><h3>Results</h3><div>MNG recorded the radial nerve’s evoked magnetic field in all cases, and the neural activity of the radial nerve at the upper arm was visualized using reconstructed currents. The mean conduction velocity calculated from the peak latency of the inward currents was 43.9 m/s for distal measurements and 57.9 m/s for proximal measurements. A 67-year-old female patient with radial nerve palsy had a disappearance of the reconstructed inward current and conduction disturbance of the axonal current, facilitating the identification of the lesion site.</div></div><div><h3>Conclusions</h3><div>MNG allowed visualization of the radial nerve activity in the upper arm and facilitated the identification of the lesion site in a patient with radial nerve palsy.</div></div><div><h3>Significance</h3><div>This method could be a useful diagnostic tool for patients with radial nerve palsy.</div></div>","PeriodicalId":45697,"journal":{"name":"Clinical Neurophysiology Practice","volume":"9 ","pages":"Pages 283-291"},"PeriodicalIF":2.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142698310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Directional deep brain stimulation of the centromedian thalamic nucleus reduces DBS-induced ataxia and dysarthria in Lennox-Gastaut Syndrome: A single case study","authors":"Stephan Neidhart ,&nbsp;Oona Kohnen ,&nbsp;Lennart Stieglitz ,&nbsp;Lukas Imbach","doi":"10.1016/j.cnp.2024.08.001","DOIUrl":"10.1016/j.cnp.2024.08.001","url":null,"abstract":"<div><h3>Background</h3><p>We present a case of a 46-year-old man with Lennox-Gastaut syndrome and drug-resistant epilepsy. An adjunctive neurostimulation therapy strategy was implemented involving bilateral deep brain stimulation (DBS) of the centromedian thalamic nucleus (CMT).</p></div><div><h3>Methods</h3><p>Robotically assisted implantation of bilateral DBS directional lead system with 8 contacts in the CMT was performed. The clinical course was assessed in repeated in-patient follow-ups.</p></div><div><h3>Results</h3><p>Initial DBS stimulation resulted in progressive ataxia and dysarthria significantly beyond the level seen before surgery. Deactivation of DBS coincided with improvement of dysarthria. A DBS stimulation paradigm with reduction of lateral and superior stimulation resulted in improvement and eventually complete resolution of the stimulation side effect.</p></div><div><h3>Discussion</h3><p>This case suggests that stimulation-induced dysarthria in DBS can be improved by targeted reduction of lateral and/or superior thalamic stimulation. When dysarthria and ataxia occur during DBS, directed stimulation to medial thalamic structures and more inferior electrode contacts offers a promising strategy to reduce side effects while maintaining positive effects.</p></div>","PeriodicalId":45697,"journal":{"name":"Clinical Neurophysiology Practice","volume":"9 ","pages":"Pages 233-235"},"PeriodicalIF":2.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2467981X24000222/pdfft?md5=be5e66cca745f2972659627bfc20c150&pid=1-s2.0-S2467981X24000222-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142097607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The value of ultrasound-guidance of nerves and muscles for patient tolerance and parameters electrodiagnostic studies","authors":"Marie Laure Inghilleri ,&nbsp;Sandrine Alonso ,&nbsp;Hélène Moron ,&nbsp;Hector Ruiz ,&nbsp;Sophie Bastide ,&nbsp;Sarah Coudray","doi":"10.1016/j.cnp.2024.01.003","DOIUrl":"10.1016/j.cnp.2024.01.003","url":null,"abstract":"<div><h3>Objective</h3><p>To assess impact of ultrasound guidance (USG) on patient’s perception of nerve conduction studies (NCS).</p></div><div><h3>Methods</h3><p>In this single-center, randomized, sham-controlled, parallel, single-blind trial, we evaluated ultrasound (US) in identifying NCS stimulation site. Consecutive adults (18–80 old) without neuropathy referred for NCS were electronically randomized 1:1 to USG or Sham US. The primary outcome was sensory supramaximal intensity (SSMI) for each site/nerve; motor supramaximal intensity (MSMI), amplitudes, number of non-routine muscle punctured, Visual Analogue Scale (VAS), satisfaction were secondary outcomes.</p></div><div><h3>Results</h3><p>290 participants were randomized, with 145 in the USG and 144 Sham US groups, respectively. No difference in SSMI, CMAP or SNAP, VAS, satisfaction was recorded. With USG, the median at the elbow and fibular MMSI were lower (p = 0.04; p = 0.02). With normal NCS or overweight and obese subgroups patients had lower median SSMI (p = 0.05/ p = 0.02), higher median and sural SNAP with normal NCS (p = 0.04; p = 0.007) and the sural SNAP for the expert US subgroup (p = 0.02).</p></div><div><h3>Conclusions</h3><p>USG is useful for nerves, that are anatomically variable or in obesity. The sural SNAP gain with US in the normal NCS subgroup could facilitate routine NCS.</p></div><div><h3>Significance</h3><p>In standard NCS the USG does not modify the patient’s tolerance.</p><p><strong>Trial Registration:</strong> clinicaltrials.gov (NCT03868189).</p></div>","PeriodicalId":45697,"journal":{"name":"Clinical Neurophysiology Practice","volume":"9 ","pages":"Pages 78-84"},"PeriodicalIF":1.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2467981X24000064/pdfft?md5=b429328969813cf5ba4ede5768daa0d1&pid=1-s2.0-S2467981X24000064-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139637403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Пepeвoд и aдaптaция для pyccкoгo языкa пepecмoтpeннoгo глoccapия тepминoв, нaибoлee чacтo иcпoльзyeмыx в клиничecкoй элeктpoэнцeфaлoгpaфии, и oбнoвлённoгo пpeдлoжeния пo фopмe зaключeния ЭЭГ (IFCN, 2017 г.)","authors":"Mikhail Sinkin ,&nbsp;Nadezhda Kvaskova ,&nbsp;Vasily Nogovitsyn ,&nbsp;Alexey Troitsky ,&nbsp;Irina Ivanova ,&nbsp;Alexandra Belyakova-Bodina ,&nbsp;Amayak Broutian","doi":"10.1016/j.cnp.2024.01.004","DOIUrl":"10.1016/j.cnp.2024.01.004","url":null,"abstract":"","PeriodicalId":45697,"journal":{"name":"Clinical Neurophysiology Practice","volume":"9 ","pages":"Pages 138-161"},"PeriodicalIF":1.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2467981X24000076/pdfft?md5=6770f16b4d4b1ac193d5b3645e4ad0e3&pid=1-s2.0-S2467981X24000076-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139877901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Compound muscle action potential of whole-forearm flexors: A clinical biomarker for inclusion body myositis","authors":"Tomoo Mano ,&nbsp;Naohiko Iguchi ,&nbsp;Naoki Iwasa ,&nbsp;Nanami Yamada ,&nbsp;Kazuma Sugie","doi":"10.1016/j.cnp.2024.03.003","DOIUrl":"https://doi.org/10.1016/j.cnp.2024.03.003","url":null,"abstract":"<div><h3>Objective</h3><p>This study aimed to investigate the potential of whole-forearm flexor muscle (WFFM) compound muscle action potential (CMAP) as a quantitative biomarker for inclusion body myositis (IBM) pathology.</p></div><div><h3>Methods</h3><p>We prospectively enrolled 14 consecutive patients (10 men and 4 women) diagnosed with IBM based on muscle biopsies. We evaluated the baseline-to-peak amplitude of the WFFM CMAP and other quantitative parameters, including grip and pinch strength, Inclusion Body Myositis Functional Rating Scale (IBMFRS) score, and other routine muscle CMAP amplitudes.</p></div><div><h3>Results</h3><p>The WFFM CMAP was strongly correlated with disease duration and the IBMFRS score. The WFFM CMAP on the more affected side was lower than that on the less affected side. Furthermore, grip power was strongly correlated with the WFFM CMAP, whereas lateral pinch strength was strongly correlated with the WFFM and first dorsal interosseous CMAPs. The 3-point pinch strength was also correlated with the WFFM CMAP.</p></div><div><h3>Conclusions</h3><p>This study demonstrates that the WFFM CMAP may serve as a biomarker of severity in IBM.</p></div><div><h3>Significance</h3><p>Identification of this biomarker can support drug development, diagnosis, prognosis, and treatment options for patients with IBM.</p></div>","PeriodicalId":45697,"journal":{"name":"Clinical Neurophysiology Practice","volume":"9 ","pages":"Pages 162-167"},"PeriodicalIF":1.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2467981X24000143/pdfft?md5=c5ee443e624833861e41f2e57e89ec24&pid=1-s2.0-S2467981X24000143-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140651037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surface recording of the H-reflex from a relaxed flexor carpi ulnaris: Reliability and normative values for healthy young adults","authors":"Hesham N. Alrowayeh","doi":"10.1016/j.cnp.2024.06.001","DOIUrl":"10.1016/j.cnp.2024.06.001","url":null,"abstract":"<div><p><em>Objective:</em> H-reflex recordings of the relaxed flexor carpi ulnaris (FCU) muscle are not frequently performed in clinical or laboratory settings. There are no normative values or reliability standards. This is most likely because of technical difficulties associated with this technique. This study performed surface recordings of the H-reflex of relaxed FCU muscles to establish the normative values and the reliability of these recordings. <em>Methods:</em> The maximum amplitude and latency of the FCU H-reflex were recorded bilaterally in 53 healthy young adults. Normative values and interclass correlation coefficients (ICCs) were calculated. <em>Results:</em> The amplitude of the relaxed FCU H-reflex were recorded in nearly all participants (96 %). The FCU H-reflex average maximum amplitude was 1.35 mV. The average latency was 18.8 ms. H-reflex amplitude and latency were not statistically different among gender or limb sides. Amplitude and latency were recoded reliably both within and between sessions with ICCs ranging from 0.96 to 0.99. <em>Conclusions:</em> Recordings of the relaxed FCU H-reflex were readily available and could be assessed reliably within and between sessions. <em>Significance:</em> This method might be used more frequently in clinical and laboratory settings to examine C7 and C8 spinal segments and upper limb muscle normal function or neuromuscular pathology.</p></div>","PeriodicalId":45697,"journal":{"name":"Clinical Neurophysiology Practice","volume":"9 ","pages":"Pages 205-210"},"PeriodicalIF":2.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2467981X24000179/pdfft?md5=13b4b259c3ef8951cee3bc76e41fad76&pid=1-s2.0-S2467981X24000179-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141402216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Real-time artificial intelligence-based texture analysis of muscle ultrasound data for neuromuscular disorder assessment","authors":"Yoshikatsu Noda ,&nbsp;Kenji Sekiguchi ,&nbsp;Shun Matoba ,&nbsp;Hirotomo Suehiro ,&nbsp;Katsuya Nishida ,&nbsp;Riki Matsumoto","doi":"10.1016/j.cnp.2024.08.003","DOIUrl":"10.1016/j.cnp.2024.08.003","url":null,"abstract":"<div><h3>Objective</h3><p>Many artificial intelligence approaches to muscle ultrasound image analysis have not been implemented on usable devices in clinical neuromuscular medicine practice, owing to high computational demands and lack of standardised testing protocols. This study evaluated the feasibility of using real-time texture analysis to differentiate between various pathological conditions.</p></div><div><h3>Methods</h3><p>We analysed 17,021 cross-sectional ultrasound images of the biceps brachii of 75 participants, including 25 each with neurogenic disorders, myogenic disorders, and healthy controls. The size and location of the regions of interest were randomly selected to minimise bias. A random forest classifier utilising texture features such as Dissimilarity and Homogeneity was developed and deployed on a mobile PC, enabling real-time analysis.</p></div><div><h3>Results</h3><p>The classifier distinguished patients with an accuracy of 81 %. Echogenicity and Contrast from the Co-Occurrence Matrix were significant predictive features. Validation on 15 patients achieved accuracies of 78 %/93 % per image/patient over 15-second videos, respectively. The use of a mobile PC facilitated real-time estimation of the underlying pathology during ultrasound examination, without influencing procedures.</p></div><div><h3>Conclusions</h3><p>Real-time automatic texture analysis is feasible as an adjunct for the diagnosis of neuromuscular disorders.</p></div><div><h3>Significance</h3><p>Artificial intelligence using texture analysis with a light computational load supports the semi-quantitative evaluation of neuromuscular ultrasound.</p></div>","PeriodicalId":45697,"journal":{"name":"Clinical Neurophysiology Practice","volume":"9 ","pages":"Pages 242-248"},"PeriodicalIF":2.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2467981X24000246/pdfft?md5=431aeb810595f6ab00be360d3d1f8ae9&pid=1-s2.0-S2467981X24000246-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142097565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}