Clinical Neurophysiology Practice最新文献_第3页

Multiple factors contribute to pupillary light reflex: implications for screening of traumatic brain injury in military service members 多种因素影响瞳孔光反射：对军人创伤性脑损伤筛查的意义

IF 2

Clinical Neurophysiology Practice Pub Date : 2025-01-01 DOI: 10.1016/j.cnp.2025.07.002

Michael N. Dretsch , Katie M. Williams , Diana P. Evans , Katrina S. Monti , Brian J. Guise , Mark L. Ettenhofer , Jamie N. Hershaw

{"title":"Multiple factors contribute to pupillary light reflex: implications for screening of traumatic brain injury in military service members","authors":"Michael N. Dretsch , Katie M. Williams , Diana P. Evans , Katrina S. Monti , Brian J. Guise , Mark L. Ettenhofer , Jamie N. Hershaw","doi":"10.1016/j.cnp.2025.07.002","DOIUrl":"10.1016/j.cnp.2025.07.002","url":null,"abstract":"<div><h3>Objectives</h3><div>This study aimed to assess the contribution of demographics, medical history, and psychological health to pupillary light reflex (PLR) indices in Service members with and without a history of mild traumatic brain injury (mTBI).</div></div><div><h3>Methods</h3><div>PLR data from NeurOptics NPi-300 were analyzed on 216 participants who were categorized as non-injured controls (NIC), mTBI with no loss of consciousness (mTBI<sup>LOC-</sup>), or mTBI with LOC (mTBI<sup>LOC+</sup>). Multiple independent regression models were conducted for each PLR index to assess the contribution of these factors to the variability of PLR indices by group.</div></div><div><h3>Results</h3><div>There were no significant group differences on the PLR indices. Age was a significant factor across groups, but more robust for those with mTBI. Sleep duration, injury characteristics, and psychological health effects on PLR indices were primarily observed in the mTBI<sup>LOC+</sup> group. Posttraumatic stress and sex were not significant predictors in any of the models.</div></div><div><h3>Conclusions</h3><div>When using PLR for screening of mTBI, an individual’s age, history of prior mTBI, total lifetime TBI-related alterations in consciousness, sleep, and anxiety and depression symptoms should be considered when interpreting PLR metrics.</div></div><div><h3>Significance</h3><div>Controlling for these factors is essential for validating the use of PLR for screening of mTBI.</div></div>","PeriodicalId":45697,"journal":{"name":"Clinical Neurophysiology Practice","volume":"10 ","pages":"Pages 256-264"},"PeriodicalIF":2.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144605723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Averted weakness from a large Martin-Gruber anastomosis 避免了马丁-格鲁伯吻合术造成的虚弱。

IF 2

Clinical Neurophysiology Practice Pub Date : 2025-01-01 DOI: 10.1016/j.cnp.2024.12.003

Emily Cheung, Karl Ng

引用次数: 0

Comparative analysis of signal quality and usability for a novel wireless, wearable EEG sensor 一种新型无线可穿戴脑电图传感器的信号质量和可用性对比分析

IF 2

Clinical Neurophysiology Practice Pub Date : 2025-01-01 DOI: 10.1016/j.cnp.2025.05.004

Vamshi K. Muvvala , Avidor B. Kazen , Tyler J. Newton , Zoë Tosi , Michael Elwood , Mark J. Lehmkuhle , Tobias Loddenkemper , Mark C. Spitz , Laura Strom , Daniel Friedman , Mitchell A. Frankel

{"title":"Comparative analysis of signal quality and usability for a novel wireless, wearable EEG sensor","authors":"Vamshi K. Muvvala , Avidor B. Kazen , Tyler J. Newton , Zoë Tosi , Michael Elwood , Mark J. Lehmkuhle , Tobias Loddenkemper , Mark C. Spitz , Laura Strom , Daniel Friedman , Mitchell A. Frankel","doi":"10.1016/j.cnp.2025.05.004","DOIUrl":"10.1016/j.cnp.2025.05.004","url":null,"abstract":"<div><h3>Objective</h3><div>This study details the design, efficacy, and usability of a novel wearable, wireless electroencephalography (EEG) sensor designed for extended-duration clinical monitoring in any environment.</div></div><div><h3>Methods</h3><div>Simultaneous EEG recordings from REMI sensors and a conventional scalp-EEG recording system were conducted across two cohorts: 1) participants undergoing routine epilepsy seizure monitoring and 2) healthy volunteers performing tasks to induce common EEG artifacts. Comparative time and spectral-based analyses were conducted between the recording modalities. Sensor usability was also evaluated.</div></div><div><h3>Results</h3><div>The temporal dynamics and signal morphology of artifacts and electrographic seizures were visually similar between the REMI sensor and conventional scalp-EEG. Additionally, spectral correlation between the two systems was high across all event types, ranging from 0.86 to 0.94. Patient-reported acceptance was also strong, with 69% of participants rating the sensors as comfortable to wear.</div></div><div><h3>Conclusions</h3><div>The REMI sensor showed strong agreement with conventional scalp-EEG in the signal characteristics of physiological artifacts and electrographic seizures. The positive comfort feedback further supports the REMI sensors’ everyday utility.</div></div><div><h3>Significance</h3><div>Although limited in electrode coverage compared to conventional scalp-EEG recording systems, the REMI sensor records comparable high-fidelity EEG data in both time and spectral domains. REMI sensor’s recording quality and wearability facilitate extended-duration monitoring in everyday environments.</div></div>","PeriodicalId":45697,"journal":{"name":"Clinical Neurophysiology Practice","volume":"10 ","pages":"Pages 292-300"},"PeriodicalIF":2.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144655230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quantitative electroencephalography in the diagnosis of dementia with Lewy bodies 定量脑电图在路易体痴呆诊断中的应用

IF 2

Clinical Neurophysiology Practice Pub Date : 2025-01-01 DOI: 10.1016/j.cnp.2025.06.008

Abhimanyu Mahajan , Alberto Jaramillo-Jimenez , Anita D’Anselmo , Giulia Prete , Lucrezia Bristot , Sara Varanese , Alberto Di Domenico , Nicola Mammarella , Luca Tommasi , Michele Tinazzi , Dag Aarsland , Claudio Babiloni , Alberto J. Espay , Laura Bonanni

{"title":"Quantitative electroencephalography in the diagnosis of dementia with Lewy bodies","authors":"Abhimanyu Mahajan , Alberto Jaramillo-Jimenez , Anita D’Anselmo , Giulia Prete , Lucrezia Bristot , Sara Varanese , Alberto Di Domenico , Nicola Mammarella , Luca Tommasi , Michele Tinazzi , Dag Aarsland , Claudio Babiloni , Alberto J. Espay , Laura Bonanni","doi":"10.1016/j.cnp.2025.06.008","DOIUrl":"10.1016/j.cnp.2025.06.008","url":null,"abstract":"<div><div>The spectral analysis of the resting-state eyes-closed electroencephalographic (rsEEG) activity typically shows abnormal delta (< 4 Hz), theta (4–7 Hz), and alpha (8–12 Hz) power in older patients with cognitive deficits due to progressive neurodegenerative diseases. Interestingly, abnormally prominent posterior rsEEG power < 8 Hz with periodic fluctuations in the pre-alpha/theta range has been considered a supportive biomarker for diagnosing patients with prodromal or manifest dementia due to Lewy bodies (DLB) in international guidelines. Here, a panel of experts shortly reviews the concepts of thalamocortical dysrhythmia as a possible neurophysiological oscillatory mechanism generating those rsEEG abnormalities in DLB patients. It also recommends how to record and quantitatively analyze rsEEG activity in prodromal and manifesting DLB patients for the application of that cost-effective and largely available diagnostic procedure in clinical practice.</div></div>","PeriodicalId":45697,"journal":{"name":"Clinical Neurophysiology Practice","volume":"10 ","pages":"Pages 222-233"},"PeriodicalIF":2.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144548595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prognostic factors of mechanical ventilation in Guillain–Barré syndrome among adults and children in Vietnam 越南成人和儿童格林-巴- <s:1>综合征机械通气预后因素分析

IF 2

Clinical Neurophysiology Practice Pub Date : 2025-01-01 DOI: 10.1016/j.cnp.2025.02.009

Hung Hoang Dang , Khang Vinh Nguyen , Si Tri Le , Thuy Thi Vu , Vy Thi Yen Le , Thang Ba Nguyen , Hieu Le Trung Nguyen

{"title":"Prognostic factors of mechanical ventilation in Guillain–Barré syndrome among adults and children in Vietnam","authors":"Hung Hoang Dang , Khang Vinh Nguyen , Si Tri Le , Thuy Thi Vu , Vy Thi Yen Le , Thang Ba Nguyen , Hieu Le Trung Nguyen","doi":"10.1016/j.cnp.2025.02.009","DOIUrl":"10.1016/j.cnp.2025.02.009","url":null,"abstract":"<div><h3>Objective</h3><div>Numerous studies have investigated predictors for mechanical ventilation (MV) in Guillain-Barré syndrome (GBS), with varying results. This study identifies factors associated with MV in both populations in Vietnam.</div></div><div><h3>Methods</h3><div>We retrospectively collected data on GBS patients at Children’s Hospital 2 and the University Medical Center Ho Chi Minh City from 2017 to 2021. Clinical characteristics were analyzed using multivariable logistic regression to identify predictors of MV. A bootstrapping stepwise approach was used to select the most appropriate predictors for the model.</div></div><div><h3>Results</h3><div>A total of 108 adults and 112 children were included, with 15 adults (13.8 %) and 10 children (8.9 %) requiring MV. Dysautonomia and facial palsy/bulbar weakness were more common in ventilated patients (P < 0.05). Multivariable analysis identified dysautonomia as the only significant predictor for MV in both adults (OR: 7.43, 95 % CI: 1.78–30.98) and children (OR: 13.6, 95 % CI: 1.20–154.79).</div></div><div><h3>Conclusions</h3><div>Dysautonomia is a significant predictor of MV in adults and children with GBS. Although facial palsy and bulbar weakness were not statistically significant predictors, their presence warrants careful monitoring.</div></div><div><h3>Significance</h3><div>This study provides insights into GBS in Vietnam and underscores dysautonomia as a predictor for MV, distinguishing it from findings in previous prognostic models.</div></div>","PeriodicalId":45697,"journal":{"name":"Clinical Neurophysiology Practice","volume":"10 ","pages":"Pages 90-94"},"PeriodicalIF":2.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143600923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correlation between decremental responses in repetitive nerve stimulation and disease progression rate in patients with amyotrophic lateral sclerosis 肌萎缩性脊髓侧索硬化症患者重复性神经刺激的递减反应与疾病进展率之间的相关性

IF 2

Clinical Neurophysiology Practice Pub Date : 2025-01-01 DOI: 10.1016/j.cnp.2025.02.003

Yuki Fujii , Takamichi Kanbayashi , Kazusa Takahashi , Yuichi Hamada , Shunsuke Kobayashi , Masahiro Sonoo

{"title":"Correlation between decremental responses in repetitive nerve stimulation and disease progression rate in patients with amyotrophic lateral sclerosis","authors":"Yuki Fujii , Takamichi Kanbayashi , Kazusa Takahashi , Yuichi Hamada , Shunsuke Kobayashi , Masahiro Sonoo","doi":"10.1016/j.cnp.2025.02.003","DOIUrl":"10.1016/j.cnp.2025.02.003","url":null,"abstract":"<div><h3>Objective</h3><div>Decrement responses in repetitive nerve stimulation (RNS) are theoretically expected to correlate with the disease progression speed in amyotrophic lateral sclerosis (ALS). However, actual results have been controversial. We investigated this issue using ΔFS calculated from the ALS functional rating scale revised version (ALSFRS-R) and the duration of illness.</div></div><div><h3>Methods</h3><div>RNS results of the abductor pollicis brevis, trapezius, and deltoid muscles in our previous study were reviewed. We investigated correlations and multiple regressions regarding decremental percentage (Decr%), the amplitude of the initial compound muscle action potential (Amp), and progression speed parameters, i.e. ΔFS or ΔUL-FS, the latter being the ΔFS for the upper-limb questions in ALSFRS-R.</div></div><div><h3>Results</h3><div>Included subjects were 124 patients with ALS, 47 of whom were upper-limb onset. Multiple regression analyses revealed that Decr% is largely determined by Amp and that Δ FS or ΔUL-FS showed no or little contributions to Decr%.</div></div><div><h3>Conclusions</h3><div>Decremental responses in RNS does not predict the speed of progression of the functional impairment in patients with ALS.</div></div><div><h3>Significance</h3><div>This study suggests that the decremental responses in RNS in ALS are contributed by the impaired neuromuscular transmission in chronic sprouts following extensive reinnervation, as well as by the immature sprouts.</div></div>","PeriodicalId":45697,"journal":{"name":"Clinical Neurophysiology Practice","volume":"10 ","pages":"Pages 40-46"},"PeriodicalIF":2.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143488300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Changing characteristics of somatosensory evoked potentials in adolescents 青少年体感诱发电位的变化特征

IF 2

Clinical Neurophysiology Practice Pub Date : 2025-01-01 DOI: 10.1016/j.cnp.2025.03.004

Aoi Mase , Manabu Shibasaki , Hiroki Nakata

{"title":"Changing characteristics of somatosensory evoked potentials in adolescents","authors":"Aoi Mase , Manabu Shibasaki , Hiroki Nakata","doi":"10.1016/j.cnp.2025.03.004","DOIUrl":"10.1016/j.cnp.2025.03.004","url":null,"abstract":"<div><h3>Objective</h3><div>We investigated changing characteristics of somatosensory processing in adolescents, particularly sex differences, by comparing children, young adults, and males and females.</div></div><div><h3>Methods</h3><div>Participants included 26 elementary school children (ESC), 36 adolescents (ADO), and 36 college students (CS). We recorded somatosensory evoked potentials (SEPs) using electrical stimulation of the right median nerve. Peak latencies and amplitudes were measured for P12, N15, P18, and N30 at Fz, and for P12 (P1), N18 (N1), P22 (P2), N27 (N2), P3, N3, P45 (P4), and N60 (N4) at C3′.</div></div><div><h3>Results</h3><div>The P22 (P2) amplitude at C3′ decreased with age. The N15 amplitude at Fz was larger in females across all groups. P3 and N3 occurrence at C3′ decreased with age but remained high in ADO compared to CS. Correlation analysis showed a significant negative correlation between P22 (P2) amplitude at C3′ and age in ADO boys, but not in ADO girls, ESC boys, or ESC girls.</div></div><div><h3>Conclusions</h3><div>Somatosensory processing in ADO is not as mature as in CS, with sex differences between ADO boys and girls.</div></div><div><h3>Significance</h3><div>Our findings may aid understanding of neural activity in children with developmental disorders, supporting sensory-based therapies.</div></div>","PeriodicalId":45697,"journal":{"name":"Clinical Neurophysiology Practice","volume":"10 ","pages":"Pages 141-149"},"PeriodicalIF":2.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143820946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Shear wave elastography as a marker of anisotropy in denervated muscle tissue 剪切波弹性图作为去神经支配肌肉组织各向异性的标志

IF 2

Clinical Neurophysiology Practice Pub Date : 2025-01-01 DOI: 10.1016/j.cnp.2025.02.007

Olli Kutvonen , Sari-Leena Himanen , Katri Mäkelä

{"title":"Shear wave elastography as a marker of anisotropy in denervated muscle tissue","authors":"Olli Kutvonen , Sari-Leena Himanen , Katri Mäkelä","doi":"10.1016/j.cnp.2025.02.007","DOIUrl":"10.1016/j.cnp.2025.02.007","url":null,"abstract":"<div><h3>Objectives</h3><div>To assess the capability of shear wave elastography (SWE) to detect muscle denervation.</div></div><div><h3>Methods</h3><div>36 patients underwent electrodiagnostic studies (EDX) of the lower limbs and volunteered to undergo ultrasound examination of the Tibialis anterior (TA) and the Gastrocnemius medialis (GCM) muscles. A variable reflecting the level of anisotropy was created by calculating the difference between the longitudinal and transverse shear wave velocity (SWE-D).</div></div><div><h3>Results</h3><div>In the TA muscles, SWE-D correlated negatively with the quantity of fibrillation potentials (FP) and the degree of interference pattern (IP) reduction (p = 0.032, r = -0.185 and p = 0.006, r = -0.236, respectively). In the GCM muscles, SWE-D only correlated with the amount of IP reduction among patients of normal weight (p = 0.030, r = -0.285). There was also a significant difference in the overall SWE-D values in the GCM muscles between patients of normal weight and obese patients (p = 0.007).</div></div><div><h3>Conclusions</h3><div>Loss of anisotropy caused by denervation of muscle tissue may be measured quantitatively by calculating the differences between longitudinal and transverse shear wave velocities. However, obesity seems to hinder the SWE-based assessment of muscle denervation.</div></div><div><h3>Significance</h3><div>Being able to measure anisotropy caused by denervation acts as a base for further development of SWE methods to evaluate neurogenic injury.</div></div>","PeriodicalId":45697,"journal":{"name":"Clinical Neurophysiology Practice","volume":"10 ","pages":"Pages 95-103"},"PeriodicalIF":2.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143619967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The diagnostic yield of a first EEG in children with suspected epilepsy: A retrospective age-related comparison between awake and sleep recordings 怀疑癫痫的儿童首次脑电图的诊断率：清醒和睡眠记录之间的回顾性年龄相关比较

IF 2

Clinical Neurophysiology Practice Pub Date : 2025-01-01 DOI: 10.1016/j.cnp.2025.05.002

Greta Gustafsson , Anders Broström , Eva Svanborg , Magnus Vrethem , Martin Ulander

{"title":"The diagnostic yield of a first EEG in children with suspected epilepsy: A retrospective age-related comparison between awake and sleep recordings","authors":"Greta Gustafsson , Anders Broström , Eva Svanborg , Magnus Vrethem , Martin Ulander","doi":"10.1016/j.cnp.2025.05.002","DOIUrl":"10.1016/j.cnp.2025.05.002","url":null,"abstract":"<div><h3>Objectives</h3><div>Previous research has indicated a low diagnostic yield of initial EEGs in epilepsy diagnosis in children. This study aimed at exploring factors affecting the diagnostic yield of a first EEG in different ages, and factors affecting the choice of EEG method.</div></div><div><h3>Methods</h3><div>1097 EEGs performed as first recordings in children with suspected epilepsy were retrospectively analysed and divided into age groups: ≤ 5, 6–11 and 12–17 years. EEGs were classified as wake recordings with or without provocations, and sleep recordings: spontaneous sleep, sleep induced by deprivation or by melatonin premedication.</div></div><div><h3>Results</h3><div>Epileptiform activity was found in 18 % of all patients, most common (30 %) in children 6–11 years old. It was more likely to be detected in melatonin-induced sleep EEGs compared to other types of sleep EEG. Presence of epileptiform discharges were positively associated to age, sleep, neurological and/or intellectual comorbidity in all children.</div></div><div><h3>Conclusions</h3><div>The prevalence of epileptiform activity varies depending on the child́s age. Sleep EEG is advantageous as first recording, especially in very young children or with neurological comorbidity.</div></div><div><h3>Significance</h3><div>Melatonin-induced sleep EEG has higher diagnostic yield compared to other types of sleep EEG. Age, seizure semiology and comorbidity affect the choice of EEG method.</div></div>","PeriodicalId":45697,"journal":{"name":"Clinical Neurophysiology Practice","volume":"10 ","pages":"Pages 181-187"},"PeriodicalIF":2.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144290883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Brachial radiculopathy with intact central nervous system imaging following carbon monoxide poisoning: A case report 一氧化碳中毒后神经根病伴完整中枢神经系统影像学1例

IF 2

Clinical Neurophysiology Practice Pub Date : 2025-01-01 DOI: 10.1016/j.cnp.2025.07.004

Zhiyong Lin , Jierong Mo , Peiyi Liu , Zhiquan Li , Ran Zhan , Jun Jiang , Tianen Zhou

{"title":"Brachial radiculopathy with intact central nervous system imaging following carbon monoxide poisoning: A case report","authors":"Zhiyong Lin , Jierong Mo , Peiyi Liu , Zhiquan Li , Ran Zhan , Jun Jiang , Tianen Zhou","doi":"10.1016/j.cnp.2025.07.004","DOIUrl":"10.1016/j.cnp.2025.07.004","url":null,"abstract":"<div><h3>Objective</h3><div>To report and analyze a unique case of selective brachial plexopathy following carbon monoxide poisoning without central nervous system involvement.</div></div><div><h3>Methods</h3><div>Clinical examination, laboratory tests, neuroimaging, serial electrophysiological studies, and functional assessments were performed on a 25-year-old female presenting with severe left upper extremity weakness after CO exposure. Treatment included hyperbaric oxygen therapy, steroid therapy, and rehabilitation.</div></div><div><h3>Results</h3><div>Following carbon monoxide poisoning, the patient developed complete left upper extremity paralysis with selective C5-C7 motor deficits and preserved sensory function. Brain MRI showed no abnormalities. Electrophysiological studies confirmed preganglionic radiculopathy with reduced motor nerve amplitudes and normal sensory conduction. Ultrasonography demonstrated C5-C7 nerve root swelling. Following hyperbaric oxygen therapy, corticosteroids, and rehabilitation, motor function gradually recovered with distal grip strength reaching 86% of the unaffected side at 120-day follow-up.</div></div><div><h3>Conclusions</h3><div>This case demonstrates an uncommon manifestation of carbon monoxide poisoning characterized by isolated brachial radiculopathy with preserved central nervous system function on neuroimaging. These findings expand the recognized spectrum of carbon monoxide neurotoxicity.</div></div><div><h3>Significance</h3><div>This case expands our understanding of CO neurotoxicity beyond the traditional basal ganglia paradigm, emphasizing the importance of peripheral nervous system assessment even when central neuroimaging is normal.</div></div>","PeriodicalId":45697,"journal":{"name":"Clinical Neurophysiology Practice","volume":"10 ","pages":"Pages 324-330"},"PeriodicalIF":2.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144713191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0