Within five weeks: Rapidly grown glioblastoma discovered on repeat MRI after pathologic EEG

IF 2 Q3 NEUROSCIENCES

Clinical Neurophysiology Practice Pub Date : 2025-01-01 DOI:10.1016/j.cnp.2025.02.002

Zsuzsanna Szankai , Egle Huggenberger , Christoph Metzler , Christian Musahl , Markus Gschwind

引用次数: 0

Abstract

Background

According to the recommendations of the International League against Epilepsy, a timely workup with a brain MRI is recommended after a first epileptic seizure. However, if the MRI is unrevealing, it is normally not repeated.

Case Presentation

We present a patient with an unprovoked epileptic seizure and only slight focal abnormalities in the EEG and a normal brain MRI. Only 35 days later, after a third seizure and now a focally pathological EEG, we repeated the brain MRI and discovered a large mass in the left temporal lobe, which was resected and histologically classified as glioblastoma multiforme.

Conclusion

This case of a very fast-growing tumor suggests that recurrent seizures, with or without anti-seizure medications, or new changes in the EEG should prompt the clinician to consider a repeat brain MRI, even if the first scan was normal.

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5周内：病理脑电图后复查MRI发现快速生长的胶质母细胞瘤

根据国际抗癫痫联盟的建议，首次癫痫发作后应及时进行脑部核磁共振检查。然而，如果MRI没有显示，通常不会重复。病例介绍：我们报告了一个无因性癫痫发作的病人，脑电图和脑MRI显示只有轻微的局灶性异常。仅仅35天后，在第三次发作和局部病理脑电图后，我们重复了脑部MRI，发现左侧颞叶有一个大肿块，我们切除了这个肿块，组织学上分类为多形性胶质母细胞瘤。结论：该病例肿瘤生长迅速，提示复发性癫痫发作，无论是否使用抗癫痫药物，或脑电图的新变化应促使临床医生考虑再次进行脑部MRI检查，即使第一次扫描正常。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Neurophysiology Practice NEUROSCIENCES-

CiteScore

3.90

自引率

0.00%

发文量

审稿时长

71 days

期刊介绍： Clinical Neurophysiology Practice (CNP) is a new Open Access journal that focuses on clinical practice issues in clinical neurophysiology including relevant new research, case reports or clinical series, normal values and didactic reviews. It is an official journal of the International Federation of Clinical Neurophysiology and complements Clinical Neurophysiology which focuses on innovative research in the specialty. It has a role in supporting established clinical practice, and an educational role for trainees, technicians and practitioners.