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Recurrent Ileal Variceal Bleeding as a Diagnostic and Therapeutic Challenge 复发性回肠静脉曲张出血作为诊断和治疗的挑战
IF 0.7
Case Reports in Gastrointestinal Medicine Pub Date : 2022-04-26 DOI: 10.1155/2022/7072961
Marek Cingel, J. Benko, M. Samoš, M. Mokáň
{"title":"Recurrent Ileal Variceal Bleeding as a Diagnostic and Therapeutic Challenge","authors":"Marek Cingel, J. Benko, M. Samoš, M. Mokáň","doi":"10.1155/2022/7072961","DOIUrl":"https://doi.org/10.1155/2022/7072961","url":null,"abstract":"Introduction Massive ileal variceal bleeding is a rare intricate condition that needs rapid management and treatment. The absence of randomized clinical trials in this field leads to a lack of evidence-based diagnostic and therapeutical approaches. We present a case report describing imaging, endoscopic, and surgical procedures leading to the diagnosis and resolution of severe ileal variceal bleeding. Case Report. We admitted a 63-year-old patient for recurrent anemia and ongoing bleeding from the gastrointestinal tract presenting as enterorrhagia. We were not able to elucidate the source by endoscopic, angiographic, or nuclear imaging methods. As a last resort, we carried out a surgical procedure with peroperative enteroscopy and subsequent resection of the affected part of the intestine. Conclusion We present a patient with a case of ileal variceal bleeding, which required extensive diagnostic and therapeutic effort with a unique peroperative enteroscopic approach.","PeriodicalId":45645,"journal":{"name":"Case Reports in Gastrointestinal Medicine","volume":"36 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2022-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84029691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Case of Systemic AL Amyloidosis Diagnosed by Screening Colonoscopy 结肠镜筛查诊断系统性AL淀粉样变1例
IF 0.7
Case Reports in Gastrointestinal Medicine Pub Date : 2022-04-20 DOI: 10.1155/2022/5562281
L. Alnimer, A. Zakaria, J. Patel, Y. Samhouri, S. Ahsan, Lyle S. Goldman, S. Sorser
{"title":"A Case of Systemic AL Amyloidosis Diagnosed by Screening Colonoscopy","authors":"L. Alnimer, A. Zakaria, J. Patel, Y. Samhouri, S. Ahsan, Lyle S. Goldman, S. Sorser","doi":"10.1155/2022/5562281","DOIUrl":"https://doi.org/10.1155/2022/5562281","url":null,"abstract":"Amyloidosis encompasses several diseases associated with deposition of low-molecular-weight proteins in an abnormal configuration. In light-chain amyloidosis (AL), monoclonal free lambda (λ) or kappa (κ) light chains are the amyloid proteins involved and can deposit in almost any organ. Symptoms vary depending on presence and extent of organ involvement, and thus, clinical presentation varies. Diagnosis requires biopsy of the affected tissue, and sometimes, fat pad or bone marrow biopsy is completed initially. Prognosis of AL amyloidosis depends on the presence of cardiac involvement. Treatment of AL amyloidosis involves systemic chemotherapy and evaluation for autologous stem cell transplant. Herein, we present a case report of an asymptomatic middle-aged female who was diagnosed with AL amyloidosis during an average-risk screening colonoscopy, which is an unusual setting. We discuss the workup involved, clinical presentation, and gastroenterology-related organ involvement.","PeriodicalId":45645,"journal":{"name":"Case Reports in Gastrointestinal Medicine","volume":"8 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2022-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85034892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Two Cases of Duodenal Ulcers That Developed after Transcatheter Procedures for Unruptured Visceral Artery Aneurysms 未破裂的内脏动脉瘤经导管治疗后发生十二指肠溃疡2例
IF 0.7
Case Reports in Gastrointestinal Medicine Pub Date : 2022-04-07 DOI: 10.1155/2022/9988216
M. Iwamuro, Yusuke Kawai, M. Uka, Y. Matsui, T. Hiraki, Y. Kawahara, H. Okada
{"title":"Two Cases of Duodenal Ulcers That Developed after Transcatheter Procedures for Unruptured Visceral Artery Aneurysms","authors":"M. Iwamuro, Yusuke Kawai, M. Uka, Y. Matsui, T. Hiraki, Y. Kawahara, H. Okada","doi":"10.1155/2022/9988216","DOIUrl":"https://doi.org/10.1155/2022/9988216","url":null,"abstract":"Herein, we report two cases of duodenal ulcers that developed after transcatheter procedures for the treatment of unruptured artery aneurysms. Both patients recovered after the administration of nothing by mouth, intravenous fluids, and proton-pump inhibitors. Notably, the duodenal ulcer was unchanged in one patient six days after endovascular treatment and improved in the other patient 13 days after angiography. These cases suggest that conservative treatment is acceptable in patients with duodenal ischemia that develops as an adverse effect of endovascular procedures. The usefulness of esophagogastroduodenoscopy in such patients has also been highlighted.","PeriodicalId":45645,"journal":{"name":"Case Reports in Gastrointestinal Medicine","volume":"75 4 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2022-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90571227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
An Uncommon Presentation of Carcinosarcoma of the Stomach and a Minimally Invasive Approach for Treatment 一种罕见的胃癌肉瘤的表现和一种微创治疗方法
IF 0.7
Case Reports in Gastrointestinal Medicine Pub Date : 2022-04-07 DOI: 10.1155/2022/1047334
Anoush Calikyan, A. Boto, Valeriia Klymenko, I. Siddiqui
{"title":"An Uncommon Presentation of Carcinosarcoma of the Stomach and a Minimally Invasive Approach for Treatment","authors":"Anoush Calikyan, A. Boto, Valeriia Klymenko, I. Siddiqui","doi":"10.1155/2022/1047334","DOIUrl":"https://doi.org/10.1155/2022/1047334","url":null,"abstract":"Carcinosarcoma is a rare malignant neoplasm that is composed of both epithelial and mesenchymal tumor components. Gastric carcinosarcoma is even more rare and is often diagnosed at a late stage. In this report, we investigate a case of early gastric carcinosarcoma with regional lymph node metastasis in a 78-year-old woman. The patient underwent partial gastrectomy, lymphadenectomy, and splenectomy. The tumor was confined to the gastric submucosa, and a biopsy specimen led to a histological diagnosis of carcinosarcoma with adenocarcinoma, squamous-cell carcinoma, and undifferentiated pleomorphic sarcoma components. Metastasis was present in one lymph node and displayed osteosarcomatous differentiation. Vigilant monitoring for recurrence and metastatic disease will be required for this patient.","PeriodicalId":45645,"journal":{"name":"Case Reports in Gastrointestinal Medicine","volume":"112 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2022-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79633223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Idiopathic Nonsurgical Pneumoperitoneum in Healthy Individuals after Endoscopy: Coincidence or Consequence? 健康人内窥镜检查后的特发性非手术气腹:巧合还是后果?
IF 0.7
Case Reports in Gastrointestinal Medicine Pub Date : 2022-04-05 DOI: 10.1155/2022/7267657
Jong Soo Lee, Dong-Hoon Yang, Eun Hee Kim, Jin Hwa Park, Sung-Chul Park, H. Park
{"title":"Idiopathic Nonsurgical Pneumoperitoneum in Healthy Individuals after Endoscopy: Coincidence or Consequence?","authors":"Jong Soo Lee, Dong-Hoon Yang, Eun Hee Kim, Jin Hwa Park, Sung-Chul Park, H. Park","doi":"10.1155/2022/7267657","DOIUrl":"https://doi.org/10.1155/2022/7267657","url":null,"abstract":"Idiopathic pneumoperitoneum has an unknown etiology despite exploratory laparotomy. However, it may occur without definite abdominal symptoms; thus, adequate management could be in clinical dilemma. We experienced three cases of idiopathic nonsurgical pneumoperitoneum in healthy individuals during a health check-up. Their cases were not accompanied by any relevant etiology or definite abdominal symptoms. All of the three cases exhibited a benign clinical course. The three patients underwent an abdominal computed tomography (CT) scan as part of a health check-up program, which incidentally revealed free air in the right paracolic gutter without evidence of visceral perforation or inflammation. Among the three cases, two patients underwent colonoscopy before abdominal CT, whereas one patient did not. Two cases were completely asymptomatic and were observed without any treatment in the outpatient clinic. Only the third case with minimal symptoms was treated conservatively for a short time. If a small amount of free air typically located in the right paracolic gutter is detected in the absence of perforation during colonoscopy, close observation without unnecessary treatment would be sufficient.","PeriodicalId":45645,"journal":{"name":"Case Reports in Gastrointestinal Medicine","volume":"2 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2022-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80824428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Unfortunate Cause of Chronic Nausea and Vomiting: Mitochondrial Neurogastrointestinal Encephalomyopathy (MNGIE) 慢性恶心和呕吐的不幸原因:线粒体神经胃肠道脑肌病(MNGIE)
IF 0.7
Case Reports in Gastrointestinal Medicine Pub Date : 2022-03-30 DOI: 10.1155/2022/7398292
N. Dasu, B. Blair, C. Foster, Colin Smith
{"title":"An Unfortunate Cause of Chronic Nausea and Vomiting: Mitochondrial Neurogastrointestinal Encephalomyopathy (MNGIE)","authors":"N. Dasu, B. Blair, C. Foster, Colin Smith","doi":"10.1155/2022/7398292","DOIUrl":"https://doi.org/10.1155/2022/7398292","url":null,"abstract":"We present a unique case of a 24-year-old male who was admitted for intractable nausea, emesis, weight loss, and abdominal discomfort. The patient underwent an extensive workup and was diagnosed with mitochondrial neurogastrointestinal encephalopathy. Early diagnosis is critical to proper management of this disease process. MGNIE is a difficult disorder to diagnose given the complexity of the disease, and this case provides clinicians the proper understanding and management of such a unique and difficult diagnosis.","PeriodicalId":45645,"journal":{"name":"Case Reports in Gastrointestinal Medicine","volume":"7 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2022-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85876357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cerebral Venous Thrombosis as an Initial Presentation of Ulcerative Colitis 脑静脉血栓形成是溃疡性结肠炎的初始表现
IF 0.7
Case Reports in Gastrointestinal Medicine Pub Date : 2022-03-27 DOI: 10.1155/2022/9438757
H. Yamazaki, Akinori Sasaki, Eriko Yamaguchi, Kana Sawada, R. Okamoto, K. Saigusa, Yasuaki Motomura
{"title":"Cerebral Venous Thrombosis as an Initial Presentation of Ulcerative Colitis","authors":"H. Yamazaki, Akinori Sasaki, Eriko Yamaguchi, Kana Sawada, R. Okamoto, K. Saigusa, Yasuaki Motomura","doi":"10.1155/2022/9438757","DOIUrl":"https://doi.org/10.1155/2022/9438757","url":null,"abstract":"Cerebral venous thrombosis (CVT) is a rare complication of ulcerative colitis (UC) that is potentially fatal once it occurs. This report describes a case of CVT that led to a diagnosis of UC. A 48-year-old woman was diagnosed with CVT due to paresthesia and weakness and was hospitalized for treatment. She developed bloody diarrhea on admission and was further diagnosed with UC based on endoscopic and pathologic findings. Treatment of UC with steroids and sulfasalazine was administered immediately. Her condition improved significantly within several days following treatment. After discharge, the patient experienced no recurrence of either CVT or UC flare-up over the last five years. This report describes CVT as an initial presentation of UC. This is also the first report of a long-term follow-up following successful treatment of CVT with concomitant UC.","PeriodicalId":45645,"journal":{"name":"Case Reports in Gastrointestinal Medicine","volume":"10 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2022-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85417904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute Liver Failure following a Single Dose of Atezolizumab, as Assessed for Causality Using the Updated RUCAM 使用更新的RUCAM评估单剂量Atezolizumab后急性肝衰竭的因果关系
IF 0.7
Case Reports in Gastrointestinal Medicine Pub Date : 2022-03-23 DOI: 10.1155/2022/5090200
R. Tzadok, S. Levy, J. Aouizerate, O. Shibolet
{"title":"Acute Liver Failure following a Single Dose of Atezolizumab, as Assessed for Causality Using the Updated RUCAM","authors":"R. Tzadok, S. Levy, J. Aouizerate, O. Shibolet","doi":"10.1155/2022/5090200","DOIUrl":"https://doi.org/10.1155/2022/5090200","url":null,"abstract":"Immune checkpoint inhibitors have become major therapeutic agents in oncology over the last few years. However, they are associated with a variety of potentially severe autoimmune phenomena. We present a patient with advanced adenocarcinoma of the lung, who presented with acute liver injury two weeks following his first treatment with atezolizumab, rapidly deteriorating to fulminant liver failure. A thorough evaluation of infectious, vascular, metabolic, and autoimmune etiologies did not yield any results. Liver pathology was nonspecific. Using RUCAM as a causality assessment method indicated probable connection between atezolizumab and liver damage. To our knowledge, this is the first documented report of a patient developing acute liver failure shortly after immune checkpoint inhibitor initiation.","PeriodicalId":45645,"journal":{"name":"Case Reports in Gastrointestinal Medicine","volume":"48 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2022-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82240891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Delay in Diagnosis of Autoimmune Polyendocrine Syndrome Type 2 as a Consequence of Misinterpretation of Gastrointestinal Symptoms 自身免疫性多内分泌综合征2型误诊胃肠道症状的结果
IF 0.7
Case Reports in Gastrointestinal Medicine Pub Date : 2022-03-23 DOI: 10.1155/2022/6623020
M. Gonciarz, M. Krogulecki, Dorota Brodowska-Kania, S. Cierniak, G. Kamiński
{"title":"Delay in Diagnosis of Autoimmune Polyendocrine Syndrome Type 2 as a Consequence of Misinterpretation of Gastrointestinal Symptoms","authors":"M. Gonciarz, M. Krogulecki, Dorota Brodowska-Kania, S. Cierniak, G. Kamiński","doi":"10.1155/2022/6623020","DOIUrl":"https://doi.org/10.1155/2022/6623020","url":null,"abstract":"Background Type 2 autoimmune polyendocrine syndrome (APS-2) is characterized by the presence of at least two of three endocrinopathies: Addison's disease, autoimmune thyroiditis, and diabetes type 1. The prevalence of APS-2 is estimated to be 1 : 1000 to 1 : 20.000 in the general population. Diagnosis of APS-2 often is delayed due to its rarity and wide spectrum of clinical symptoms. Case Presentation. A 27-year-old presented with a 6-month history of abdominal pain, vomiting, diarrhea, weakness, fatigue, and 15 kg of weight loss. The patient was diagnosed with Crohn's disease in a local hospital and referred to our institution because of treatment failure. Colonoscopy performed in this hospital identified irregular mucosal erosions in terminal ileum, and the microscopy of biopsy specimens demonstrated nonspecific inflammation. On physical examination, the patient appeared cachectic. Blood pressure was 90/60 mmHg. Laboratory results were significant for severe hyponatremia and mild hyperkalemia. Morning cortisol was low, and adrenocorticotropic hormone (ACTH) concentration was high. An ACTH stimulation test did not present any increase in serum cortisol, which confirmed primary adrenal insufficiency. Antithyroid peroxidase antibody (anti-TPO) as well as both anti-21-hydroxylase antibodies and antiglutamic acid decarboxylase antibodies (GAD65) were positive. So, the diagnosis of APS-2 was made, and the replacement doses of hydrocortisone and fludrocortisone has brought a rapid improvement in all clinical symptoms; colonoscopy showed normal. Conclusion The case presented herein highlights rapidly progressive nature of untreated APS-2 and that the diagnosis of APS-2 may be challenging.","PeriodicalId":45645,"journal":{"name":"Case Reports in Gastrointestinal Medicine","volume":"5 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2022-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89440544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Diffuse Large B Cell Lymphoma with Cutaneous and Gastrointestinal Involvement 累及皮肤和胃肠道的弥漫性大B细胞淋巴瘤
IF 0.7
Case Reports in Gastrointestinal Medicine Pub Date : 2022-02-27 DOI: 10.1155/2022/2687291
A. Kyaw, T. Aye, Lin-Lin Htun
{"title":"Diffuse Large B Cell Lymphoma with Cutaneous and Gastrointestinal Involvement","authors":"A. Kyaw, T. Aye, Lin-Lin Htun","doi":"10.1155/2022/2687291","DOIUrl":"https://doi.org/10.1155/2022/2687291","url":null,"abstract":"Diffuse large B cell lymphoma (DLBCL) is the histological subtype of non-Hodgkin's lymphoma, representing approximately 30%. The most common primary extranodal sites of DLBCL are the gastrointestinal (GI) tract, the head and neck, and the skin/soft tissue. We report a case of DLBCL with cutaneous involvement presenting with skin nodules and GI manifestations such as obstructive jaundice and upper GI bleeding. Malignant cystic pancreatic tumor occupying the head and body with invasion to lower end of common bile duct and periampullary region causing biliary obstruction and mesenteric lymphadenopathy were found in abdominal computed tomography and endoscopic ultrasonography. There was also a large gastric ulcer (Forrest IIa) at the greater curvature of body of the stomach. Histopathological results of the skin and stomach were consistent with diffuse large B cell lymphoma; gastric biopsy being negative for leucocyte common antigen. The patient was considered to have disseminated DLBCL. The aim of the present case report was to present the clinical, radiological, and histological characteristics of the patient, which may aid physicians in diagnosing involvement of multiple extranodal sites in DLBCL.","PeriodicalId":45645,"journal":{"name":"Case Reports in Gastrointestinal Medicine","volume":"55 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2022-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73580067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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