Pediatric Reports最新文献

{"title":"Look at My Body: It Tells of Suffering-Understanding Psychiatric Pathology in Patients Who Suffer from Headaches, Restrictive Eating Disorders, or Non-Suicidal Self-Injuries (NSSIs).","authors":"Diletta Cristina Pratile, Marika Orlandi, Adriana Carpani, Martina Maria Mensi","doi":"10.3390/pediatric17010021","DOIUrl":"10.3390/pediatric17010021","url":null,"abstract":"<p><p><b>Background/Objectives</b>: Adolescence is a developmental stage characterized by profound physical and psychological transformations, often leading to vulnerabilities such as body dissatisfaction, identity challenges, and the use of maladaptive coping strategies. This often leads to body-related psychopathologies, including headaches, restrictive eating disorders, and non-suicidal self-injury (NSSI). The present study aimed to describe the typical functioning and features of these conditions and the differences between the three groups, and to identify the most effective assessment for predicting these conditions. <b>Methods</b>: Sixty adolescent patients (51 female; mean age = 15.34 ± 1.80) were divided into three groups: headaches, restrictive eating disorders, and NSSI, and assessed for differences in symptoms, cognitive performance, personality, functioning, and illness severity using semi-structured interviews, clinician-based scales, and performance-based tests like the Rorschach inkblot test, according to the Rorschach Performance Assessment System (R-PAS). <b>Results</b>: Individuals with headaches experienced more internalizing symptoms, had an average IQ, maintained some functioning areas, and had distorted patterns of self-other relationships with the tendency to project malevolent aspects onto others. Patients with restrictive eating disorders had high levels of depressive symptoms, above-average IQ scores, negative symptoms, moderate presence of obsessive-compulsive personality traits, disorganized thinking, and a tendency to interpret situations subjectively. Patients with NSSI showed the highest level of depressive symptoms and social anxiety symptoms, and a considerable presence of psychotic symptoms and perceptual distortions. Negative symptoms, borderline personality traits, and psychosis symptoms had the strongest predictivity. <b>Conclusions</b>: The study provides clinicians with relevant insights into the features of these conditions and highlights assessment strategies, tailored interventions, and enhanced outcomes for these vulnerable populations.</p>","PeriodicalId":45251,"journal":{"name":"Pediatric Reports","volume":"17 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11858191/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143494157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Measuring Community and Home Participation and Environmental Factors in Children with Cerebral Palsy.","authors":"Turki Aljuhani, Shaden A Alzahrani, Abeer M Aldosary, Lana A Alzamil, Rakan K Alshehri, Afnan S Gmmash, Reem A Albesher","doi":"10.3390/pediatric17010017","DOIUrl":"10.3390/pediatric17010017","url":null,"abstract":"<p><p><b>Background/Objectives</b>: Children with cerebral palsy (CP) are reported to have lower rates of participation in community and home tasks than typically developing children. Little is known about the participation levels of children with CP and the environmental factors influencing their participation in the community within the Saudi context. This study aimed to determine the degree of participation in community and home tasks in children with CP in Saudi Arabia, as well as the level of support received, and the obstacles faced by children in this context. <b>Methods</b>: Parents of 5-16-year-old children with CP (<i>n</i> = 50) completed the Participation and Environment Measure for Children and Youth (PEM-CY), and their scores were compared with those of typically developing children of the same ages (<i>n</i> = 50). This study was conducted in a hospital setting. Analyses were performed using multivariate logistic regression analyses, controlling for potential confounders. <b>Results</b>: Participation in community activities as well as home activities was reported to be significantly lower in children with CP compared to their typically developing peers in multiple domains (<i>p</i> < 0.05). Additionally, physical, cognitive, and social demands were identified as factors that made community participation more difficult for children with CP (<i>p</i> = 0.002, <i>p</i> = 0.017, and <i>p</i> = 0.029 for physical, cognitive, and social demands, respectively). The availability of personal transportation, programs, services, and financial support were identified by parents as the factors that lowered community participation levels in children with CP (<i>p</i> > 0.005). <b>Conclusions</b>: Physical, cognitive, and social demands are the main obstacles to participation for children with CP. A lack of home supplies and financial support lowered the participation of children with CP. Recognizing environmental barriers as well as providing individualized practical solutions in collaboration with the families of children with CP can assist in developing meaningful participation in community and home activities for children with CP.</p>","PeriodicalId":45251,"journal":{"name":"Pediatric Reports","volume":"17 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11858706/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143494158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Paliperidone-Induced Massive Asymptomatic Creatine Kinase Elevation in Youth: From a Case Report to Literature Review.","authors":"Aurora Grandioso, Paola Tirelli, Gianmario Forcina, Vittoria Frattolillo, Delia De Biasio, Francesco Giustino Cesaro, Pierluigi Marzuillo, Emanuele Miraglia Del Giudice, Anna Di Sessa","doi":"10.3390/pediatric17010018","DOIUrl":"10.3390/pediatric17010018","url":null,"abstract":"<p><strong>Background/objectives: </strong>Unlike rhabdomyolysis and neuroleptic malignant syndrome (NMS), massive asymptomatic creatine kinase elevation (MACKE) represents a condition commonly detected during routine screening in patients receiving antipsychotic drugs. In particular, current evidence indicates a greater incidence of this condition in patients without signs of NMS, rhabdomyolysis, or other causes of CK increase during exposure to second-generation antipsychotics (SGAs) than first-generation antipsychotics (FGAs) with a variable onset and duration. Although its pathophysiology is still not fully elucidated, MACKE has usually been recognized as a self-limiting condition, but drug discontinuation might also be required to successfully revert it. Overall, knowledge in this field is mainly extrapolated from adult data, while similar evidence in youths is still limited. As clinicians might often deal with MACKE, its understanding needs to be expanded to avoid misdiagnosis, potentially leading to wasteful healthcare spending and unfavorable patient outcomes.</p><p><strong>Methods: </strong>By reporting the first case of MACKE in an adolescent receiving an SGA, namely paliperidone, we also aimed to provide a comprehensive overview of this medical condition.</p><p><strong>Conclusions: </strong>Making a MACKE diagnosis is essential since its relevant clinical and economic implications are mainly related to unnecessary closer laboratory monitoring or therapeutic changes (e.g., drug discontinuation or switch to another medication).</p>","PeriodicalId":45251,"journal":{"name":"Pediatric Reports","volume":"17 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11858181/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143494159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prenatal Risk Factors for Brief Resolved Unexplained Events in Infants.","authors":"Luana Nosetti, Marco Zaffanello, Eliot S Katz, Elisa Morrone, Michele Abramo, Francesca Brambilla, Antonella Cromi, Giorgio Piacentini, Massimo Agosti","doi":"10.3390/pediatric17010016","DOIUrl":"10.3390/pediatric17010016","url":null,"abstract":"<p><strong>Background: </strong>Prenatal factors have been implicated in the likelihood of reporting sleep disorders in infants. The influence of prenatal and pregnancy-related factors on the incidence of brief resolved unexplained events (BRUEs) in infants has not been established.</p><p><strong>Objectives: </strong>This study aims to evaluate the prenatal and pregnancy-related factors that may contribute to the development of BRUEs in infants.</p><p><strong>Methods: </strong>A single-center, observational, and cross-sectional cohort study was conducted on mothers of children presenting to the Pediatric Clinic of the University of Insubria's Center for the Study of Respiratory Sleep Disorders with BRUEs as infants. The mothers of typically developing children were enrolled as a control group consecutively at their respective outpatient clinics. All mothers were administered comprehensive questionnaires including demographics, past medical histories, and pregnancy-related issues (weight gain, Berlin sleep-disordered breathing score, and insomnia severity index), psychological symptoms, medical history, illnesses, and medications.</p><p><strong>Results: </strong>Infants with BRUEs were delivered at an earlier gestational age. Mothers of infants with BRUEs were more likely to snore during pregnancy and have lower extremity edema during the first trimester, uterine contractions and restless legs syndrome symptoms during the second trimester, and muscle aches and aspirin usage during the third trimester. The insomnia severity index composite score was not different between the control and BRUE groups. Mothers of infants with BRUEs were less likely to report leg cramps, pregnancy-related diarrhea, fatigue, and gastroesophageal reflux.</p><p><strong>Conclusions: </strong>Mothers of infants presenting with BRUEs had more symptoms during pregnancy of snoring and uterine contractions but not insomnia and were less likely to report leg cramps, pregnancy-related diarrhea, fatigue, and gastroesophageal reflux. The reporting of this study conforms with the STROBE statement.</p>","PeriodicalId":45251,"journal":{"name":"Pediatric Reports","volume":"17 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11858546/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143494163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pediatric Wernicke Encephalopathy: A Systematic Review.","authors":"Erik Oudman, Jan W Wijnia, Janice R Bidesie, Mirjam J van Dam, Misha J Oey, Sterre Smits, Maaike van Dorp, Albert Postma","doi":"10.3390/pediatric17010015","DOIUrl":"10.3390/pediatric17010015","url":null,"abstract":"<p><strong>Background: </strong>Wernicke Encephalopathy (WE), a neurological disorder often linked to alcohol use, can also occur under non-alcoholic conditions, including in pediatric populations.</p><p><strong>Methods: </strong>This systematic review examines 88 pediatric WE cases reported over the past 30 years, encompassing diverse etiologies such as cancer (25 cases), gastrointestinal diseases (19), malnutrition (17), psychiatric disorders (13), obesity surgery (5), renal disease (4), COVID-19 (2), PICU complications (1), hyperemesis gravidarum (1), and a genetic mutation (1).</p><p><strong>Results: </strong>Prodromal symptoms included nausea (60%) and vomiting (55%). In total, 37% of the patients received parenteral nutrition without thiamine before WE diagnosis, often progressing to Wernicke-Korsakoff syndrome (WKS). Key findings revealed the classic triad of WKS, eye movement disorders (80%), mental status changes (75%), and ataxia (63%), with MRI demonstrating high diagnostic sensitivity (85%). Treatment varied widely; higher parenteral thiamine doses correlated with faster recovery and better outcomes, while insufficient dosages led to adverse effects. Full remission was achieved in 61% of cases, with improved outcomes in more recent reports due to refined dosing protocols.</p><p><strong>Conclusions: </strong>These findings underscore the importance of early recognition of nausea and vomiting as predictors of pediatric WE and the critical need to incorporate thiamine in parenteral nutrition for children. Optimal dosing remains vital for recovery, particularly in severe cases.</p>","PeriodicalId":45251,"journal":{"name":"Pediatric Reports","volume":"17 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11859456/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143494161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intrathymic Hemagioma: A Challenging Case Report with Special Focus on the Importance of Its Multidisciplinary Approach.","authors":"Milan Velimirovici, Anca Voichita Popoiu, Simona Cerbu, Calin Marius Popoiu, Florica Ramona Dorobantu, Borislav Dusan Caplar, Eugen Melnic, Anca Maria Cimpean, Larisa Cristina Tomescu, Maria Corina Stanciulescu","doi":"10.3390/pediatric17010013","DOIUrl":"10.3390/pediatric17010013","url":null,"abstract":"<p><p>Mediastinal hemangiomas, particularly those of thymic origin, are rare phenomena. Due to its rarity, this pathologic condition is not characterized as related to the angiogenic profile of hemangioma endothelial cells. The diagnosis is challenging clinically and radiologically, and biopsies may not yield a definitive answer. Surgical resection offers the material for histologic diagnosis, relieves symptoms, and has a favorable long-term prognosis for such benign tumors. Sometimes, such benign tumors may have aggressive behavior and repeated recurrences but the causes responsible for this unpredictable evolution are not actually known. A case of intrathymic hemangioma diagnosed in a 16-year-old girl is presented here. We focused equally on a multidisciplinary approach to this challenging diagnosis but also on the characterization of the hemangioma endothelial cells profile not previously performed for such type of vascular anomalies. To define an antibodies panel for the evaluation of intrathymic hemangiomas may help in the full characterization of this rare vascular lesion, and subsequently focus on the new therapeutic targets which may be applied for cases with aggressive behavior.</p>","PeriodicalId":45251,"journal":{"name":"Pediatric Reports","volume":"17 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11857899/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143494156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pictorial Review of Paediatric Limp.","authors":"Shashank Chapala, Sahana Giliyaru, Rajesh Botchu, Suvinay Saxena, Karthikeyan P Iyengar, Muthusamy Chandramohan","doi":"10.3390/pediatric17010014","DOIUrl":"10.3390/pediatric17010014","url":null,"abstract":"<p><p>A limp is an abnormal, uneven or laboured gait typically resulting from pain, weakness, or structural deformity involving the hip, lower limb, spine or abdominopelvic abnormalities. Limps in children are common and have diverse causes that can be benign to life-threatening including trauma, congenital malformations, and neoplastic diseases. Diagnosis involves identifying gait abnormality thoroughly examining history and physical exam, assessing tenderness and range of motion, and completing targeted lab and radiographic studies. We present an imaging review of various usual and unusual causes of limp in different age groups such as in toddlers (1-3 years), children (4-10 years), and adolescents (11-16 years) with a comprehensive literature review.</p>","PeriodicalId":45251,"journal":{"name":"Pediatric Reports","volume":"17 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11857996/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143494162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Surgical Timing on Outcomes in Neonatal Inguinal Hernia Repairs: A Systematic Review.","authors":"Leen Yahya Alqahtany, Arwa Alsharif, Abdulaziz Alsharif, Omar Alanazi, Manaf Altaf, Ahlam Kaleemullah, Lana Alsaedi, Hanan Ismail Wasaya, Abrar Hassan Alharbi, Osama Bawazir","doi":"10.3390/pediatric17010012","DOIUrl":"10.3390/pediatric17010012","url":null,"abstract":"<p><p>Inguinal hernia repair (IHR) is a common surgical procedure among neonates and infants; the time of surgery is one of the major factors affecting its outcomes. Our systematic review aims to evaluate the effects of surgical timing on outcomes in inguinal hernia repairs in the newborn and infant population to establish evidence-based guidelines for optimal surgical timing. A systematic search was performed in PubMed, MEDLINE, and Web of Science databases, following PRISMA guidelines. Studies evaluating neonates and infants undergoing IHR with outcomes of recurrence, complications, and postoperative recovery were included. Data were collaboratively extracted, including patient demographics, surgical approaches, perioperative complications, and long-term outcomes. Early repair (0-28 days of life) decreased the risk of hernia incarceration but also increased the risk of preoperative complications. Delayed repair (29 days to 1 year of life) showed fewer preoperative complications but increased the risk of incarceration. The outcomes were affected by variables including patient maturity and comorbidities, along with hernia severity. Neonates with a high risk for incarceration are best treated with early repair, while stable infants can be managed safely with delayed repair. More randomized trials are needed to develop standardized guidelines that balance the associated risks of neonatal versus infant repair strategies to maximize benefits.</p>","PeriodicalId":45251,"journal":{"name":"Pediatric Reports","volume":"17 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11857962/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143494155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pediatric Treatment of Anterior-Upper-Single Dental Crossbite Using a Versatile Sagittal Screw System: A Case Series.","authors":"Antonino Lo Giudice, Alessandro Polizzi","doi":"10.3390/pediatric17010011","DOIUrl":"10.3390/pediatric17010011","url":null,"abstract":"<p><strong>Background/objectives: </strong>Anterior crossbite is characterized by a reverse sagittal relationship between the maxillary and mandibular incisors. Early treatment of an anterior crossbite is advocated to avoid periodontal and traumatic consequences on lower dentition along with growth disturbances in the anterior maxilla and mandible. The present case series describes the usage of a sagittal expansion screw integrated with a removable maxillary plate or fixed appliance to correct an anterior upper single dental crossbite and outlines the clinical rationale and the protocol associated with this appliance system.</p><p><strong>Methods: </strong>A total of four children presenting anterior crossbite were treated using a sagittal expansion screw integrated into a removable plate or a fixed appliance.</p><p><strong>Results: </strong>All patients were successfully treated in less than 4 months. Overjet and overbite were normalized by the end of treatment. The orthodontic treatment received positive feedback from parents and caregivers, who seek a rapid improvement in their children's aesthetics and function. No significant discomfort or speech difficulties were reported by the parents or patients.</p><p><strong>Conclusions: </strong>The present case series would suggest that a sagittal expansion screw, integrated into both a removable and fixed appliance, can represent a valuable and versatile treatment option for correcting an anterior crossbite.</p>","PeriodicalId":45251,"journal":{"name":"Pediatric Reports","volume":"17 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11858000/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143494160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Use of PediSTAT Application by Paramedics Working in Saudi Arabia to Reduce the Risk of Medication Error for Pediatric Patients.","authors":"Nesrin Alharthy, Raghad Abuhaimed, Munirah Alturki, Shatha Alanazi, Raghad Althaqeb, Alanowd Alghaith, Abdullah Alshibani","doi":"10.3390/pediatric17010009","DOIUrl":"10.3390/pediatric17010009","url":null,"abstract":"<p><strong>Background/objectives: </strong>This study aimed to assess and compare the rates of medication error (ME) using the PediSTAT application compared to the conventional method of calculating the correct dose and determining the appropriate route of medication administration for common pediatric emergencies.</p><p><strong>Methods: </strong>A prospective cross-sectional study design was used for the study. Data were collected using a questionnaire that was distributed to certified paramedics holding a bachelor's degrees or higher and working in Riyadh City, Saudi Arabia. Alternate simple random sampling was used to recruit the participants into two groups using the same questionnaire: the PediSTAT group and the conventional method group. The questionnaire contained four pediatric emergency vignettes: cardiac arrest, asthma exacerbation, seizures, and hypoglycemia.</p><p><strong>Results: </strong>A total of 63 participants agreed to the study. Almost 80% of them were males, 81% held bachelor's degrees, and 87% were certified in pediatric resuscitation courses. The findings of the study showed that the use of the PediSTAT application increased accuracy and reduced the risk of ME for common pediatric emergencies. This was shown to be statistically significant for asthma medication dose (<i>p</i>-value < 0.001, 95% CI 0.034-0.352), midazolam dose (<i>p</i>-value = 0.012, 95% CI 0.030-0.764), and hypoglycemia medication dose (<i>p</i>-value < 0.001, 95% CI 0.046, 0.452).</p><p><strong>Conclusions: </strong>The study findings supported the use of standardized precalculated applications such as PediSTAT, which was shown to reduce the risk of ME in prehospital care for pediatric emergencies.</p>","PeriodicalId":45251,"journal":{"name":"Pediatric Reports","volume":"17 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11755567/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143025118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}