Journal of Oral and Maxillofacial Surgery Medicine and Pathology最新文献_第7页

Can ChatGPT be used as a scientific source of information on tooth extraction? ChatGPT可以作为拔牙的科学信息来源吗？

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Journal of Oral and Maxillofacial Surgery Medicine and Pathology Pub Date : 2025-02-21 DOI: 10.1016/j.ajoms.2025.02.009

Shiori Yamamoto , Masakazu Hamada , Kyoko Nishiyama , Ayako Motoki , Yusei Fujita , Narikazu Uzawa

{"title":"Can ChatGPT be used as a scientific source of information on tooth extraction?","authors":"Shiori Yamamoto , Masakazu Hamada , Kyoko Nishiyama , Ayako Motoki , Yusei Fujita , Narikazu Uzawa","doi":"10.1016/j.ajoms.2025.02.009","DOIUrl":"10.1016/j.ajoms.2025.02.009","url":null,"abstract":"<div><h3>Objective</h3><div>Tooth extraction is one of the most commonly performed dental procedures. ChatGPT uses artificial intelligence and machine learning techniques to generate human-like answers to questions. However, the amount of information that ChatGPT retrieves from the literature and media varies by language, so its response may differ depending on the language used. In this study, we investigated the quality and reliability of English and Japanese responses regarding tooth extractions provided through ChatGPT.</div></div><div><h3>Materials and methods</h3><div>The 10 most frequently asked questions by patients about tooth extraction in English and Japanese were created and posed to the artificial intelligence-based chatbot ChatGPT. Ten Japanese dentists with at least 10 years’ experience of oral and maxillofacial surgery evaluated ChatGPT responses using GQS and LS.</div></div><div><h3>Results</h3><div>Questions input in English to ChatGPT achieved a significantly higher mean GQS score and significantly lower mean LS score than questions in Japanese (both P < 0.05). The results showed significant differences between English and Japanese in the quality and reliability of chatbot performance.</div></div><div><h3>Conclusion</h3><div>ChatGPT’s answers, in both English and Japanese, were sufficiently accurate and appropriate. However, questions input in English to ChatGPT received better answers than those in Japanese. For non-native English speakers, such as Japanese, the information provided by ChatGPT may be limited or inappropriate due to the language barrier. In addition, because conditions vary from case to case, patients should consult their dentist or oral surgeon for personalized advice.</div></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":"37 5","pages":"Pages 877-882"},"PeriodicalIF":0.4,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144654140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A case of orthognathic surgery for jaw deformity with hypohidrotic ectodermal dysplasia 正颌手术治疗下颌畸形伴少汗性外胚层发育不良1例

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Journal of Oral and Maxillofacial Surgery Medicine and Pathology Pub Date : 2025-02-21 DOI: 10.1016/j.ajoms.2025.02.016

Taka-aki Tokura , Hironari Dehari , Tomohiro Igarashi , Koyo Nishiyama , Sho Miyamoto , Takanori Sasaki , Akihiro Miyazaki

{"title":"A case of orthognathic surgery for jaw deformity with hypohidrotic ectodermal dysplasia","authors":"Taka-aki Tokura , Hironari Dehari , Tomohiro Igarashi , Koyo Nishiyama , Sho Miyamoto , Takanori Sasaki , Akihiro Miyazaki","doi":"10.1016/j.ajoms.2025.02.016","DOIUrl":"10.1016/j.ajoms.2025.02.016","url":null,"abstract":"<div><div>Ectodermal dysplasia (ED) is a congenital disease that causes dysplasia in organs derived from the ectoderm. Hypohidrotic ectodermal dysplasia (HED) is the most common form of ED and is characterized by the cardinal features of hypohidrosis, hypotrichosis, and hypodontia. However, the disease rarely results in jaw deformities. Here, we report the case of an 18-year-old male patient who underwent orthognathic surgery under general anesthesia to treat a jaw deformity associated with HED. The patient presented with multiple missing teeth, hypotrichosis, and hypohidrosis, and a family history of similar symptoms. The patient was subsequently diagnosed with X-linked HED. After preoperative corrective orthodontic treatment, we performed Le Fort I osteotomy, bilateral sagittal split ramus osteotomy, and genioplasty. The patient’s body temperature was carefully monitored during the procedure due to his hypohidrosis and impaired body temperature regulation. At 2 years and 9 months after the first surgical intervention, there were notable improvements with regard to the degree of dental occlusion, height of the face, and protrusion of the chin. The patient was satisfied with the esthetic and functional outcomes of treatment. Surgeons and anesthesiologists should be aware of the treatment challenges for HED hypodontia and assure that patients understand the comprehensive treatment plans.</div></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":"37 5","pages":"Pages 978-984"},"PeriodicalIF":0.4,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144654283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Clinical efficacy and safety of tegafur, gimeracil, and oteracil potassium (S-1) monotherapy for incurable oral squamous cell carcinoma patients 替加氟、吉美拉西和奥他拉西钾（S-1）单药治疗无法治愈的口腔鳞状细胞癌的临床疗效和安全性

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Journal of Oral and Maxillofacial Surgery Medicine and Pathology Pub Date : 2025-02-19 DOI: 10.1016/j.ajoms.2025.02.015

Shoichi Sekikawa , Ayaka Tatsumi , Saki Ishikawa , Shiori Tanaka , Yuri Aiso , Takayoshi Kikuchi , Taiki Suzuki , Satoru Ogane , Takeshi Nomura , Akira Katakura , Akira Watanabe

{"title":"Clinical efficacy and safety of tegafur, gimeracil, and oteracil potassium (S-1) monotherapy for incurable oral squamous cell carcinoma patients","authors":"Shoichi Sekikawa , Ayaka Tatsumi , Saki Ishikawa , Shiori Tanaka , Yuri Aiso , Takayoshi Kikuchi , Taiki Suzuki , Satoru Ogane , Takeshi Nomura , Akira Katakura , Akira Watanabe","doi":"10.1016/j.ajoms.2025.02.015","DOIUrl":"10.1016/j.ajoms.2025.02.015","url":null,"abstract":"<div><h3>Objective</h3><div>This retrospective study aimed to investigate the overall response rate, survival time, and adverse events (AEs) after S-1 administration for incurable oral squamous cell carcinoma (OSCC) after standard therapy and report the efficacy and safety of S-1 monotherapy.</div></div><div><h3>Patients and methods</h3><div>This was a retrospective, single-center, cohort study. Twenty-eight patients with incurable OSCC were enrolled. In all patients, S-1 was administered for two weeks followed by a one-week rest. The primary outcome variables were 2-year overall survival (2yOS) and median survival time (MST) after S-1 administration, estimated using the Kaplan-Meier method. Additional outcome variables were the best overall response and AEs leading to S-1 discontinuation.</div></div><div><h3>Results</h3><div>The overall response rate (ORR) was 35.7 %. Stable disease (SD) was seen in 28.6 %, and the disease control rate (DCR) was 64.3 %. The median duration of S-1 monotherapy was 58.5 days. The 2yOS of all patients was 5.9 %, and MST was 7.1 months. In cases in which disease control (group of complete response, partial response, and SD) was achieved, 2yOS was 8.9 %, and MST was 10.2 months. AEs requiring discontinuation of S-1 occurred in 25.0 % of patients, with grade 3 or 4 neutropenia in 17.9 %, and any grade of drug-induced lung injury in 2 patients (7.1 %)</div></div><div><h3>Conclusions</h3><div>S-1 monotherapy for incurable OSCC patients could be expected to achieve an ORR of 35.7 % and DCR of 64.3 %, and it is relatively safe to administer. S-1 monotherapy is a treatment worth considering for incurable OSCC patients who have exhausted standard therapy.</div></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":"37 5","pages":"Pages 895-899"},"PeriodicalIF":0.4,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144654287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Advancing the utility of ultrasound texture analysis for lymph node metastasis detection in oral cancer 推进超声纹理分析在口腔癌淋巴结转移检测中的应用

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Journal of Oral and Maxillofacial Surgery Medicine and Pathology Pub Date : 2025-02-14 DOI: 10.1016/j.ajoms.2025.02.012

Carlos M. Ardila , Pradeep K. Yadalam

引用次数: 0

Epithelioid schwannoma in the buccal region: A case report and review of literature 颊部上皮样神经鞘瘤1例报告及文献复习

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Journal of Oral and Maxillofacial Surgery Medicine and Pathology Pub Date : 2025-02-13 DOI: 10.1016/j.ajoms.2025.02.011

Takashi Baba , Hiroshi Baba , Yu Yamaguma , Takehito Fukui , Takeshi Kaneuji , Yoshihiro Yamashita

{"title":"Epithelioid schwannoma in the buccal region: A case report and review of literature","authors":"Takashi Baba , Hiroshi Baba , Yu Yamaguma , Takehito Fukui , Takeshi Kaneuji , Yoshihiro Yamashita","doi":"10.1016/j.ajoms.2025.02.011","DOIUrl":"10.1016/j.ajoms.2025.02.011","url":null,"abstract":"<div><div>Schwannomas are common, benign peripheral nerve sheath tumors that arise from Schwann cells. Several rare morphological variants include ancient, cellular, plexiform, epithelioid, and microcystic/reticular. The epithelioid variant of schwannoma is scarce, with only a few relevant cases reported in the oral and maxillofacial regions. Herein, we report a case of epithelioid schwannoma in the buccal region. A 61-year-old woman was referred to our department from a medical clinic because of a slow-growing nodule in the buccal region, noticed 3 years before presentation. Clinical examination revealed a nodular mass measuring 20 × 20 mm. Computed tomography (CT) and magnetic resonance imaging (MRI) showed an oval lesion with a clear border on the left cheek. The outer margin of the mass exhibited opacities that appeared as multiple microcalcifications. MRI revealed a well-defined mass similar in size to that observed on CT, with low signal intensity on T1-weighted images and mildly high signal intensity on T2-weighted images. The clinical differential diagnosis includes benign tumors such as pleomorphic adenoma. The tumor was surgically excised under general anesthesia. Histopathological examination revealed multilobulated epithelioid cells arranged in nests. The tumor cells showed eosinophilic cytoplasm and uniformly round nuclei. The tumor was diagnosed as an epithelioid schwannoma. Postoperative follow-up was uneventful, and no evidence of recurrence was observed 2 years postoperatively.</div></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":"37 5","pages":"Pages 1123-1130"},"PeriodicalIF":0.4,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144654029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Retrieval of an impacted foreign body from the frontal sinus and orbit via endoscope-assisted open surgery 内窥镜辅助开放手术从额窦及眶内取出异物

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Journal of Oral and Maxillofacial Surgery Medicine and Pathology Pub Date : 2025-02-13 DOI: 10.1016/j.ajoms.2025.02.007

Orhan Asya, Yavuz Gündoğdu, Ömer Faruk Kuyumcu

引用次数: 0

Disseminated herpes zoster presenting as atypical Ramsay-Hunt syndrome with oral lesions: A case report 播散性带状疱疹表现为非典型拉姆齐-亨特综合征伴口腔病变：1例报告

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Journal of Oral and Maxillofacial Surgery Medicine and Pathology Pub Date : 2025-02-12 DOI: 10.1016/j.ajoms.2025.02.010

Saki Maruyama , Norihisa Ichimura , Yukiko Wakayama , Masahiro Omori , Kohei Sakaguchi , Kazuto Okabe , Hiroshi Maruyama , Hideharu Hibi

{"title":"Disseminated herpes zoster presenting as atypical Ramsay-Hunt syndrome with oral lesions: A case report","authors":"Saki Maruyama , Norihisa Ichimura , Yukiko Wakayama , Masahiro Omori , Kohei Sakaguchi , Kazuto Okabe , Hiroshi Maruyama , Hideharu Hibi","doi":"10.1016/j.ajoms.2025.02.010","DOIUrl":"10.1016/j.ajoms.2025.02.010","url":null,"abstract":"<div><div>Shingles is caused by reactivation of latent varicella-zoster virus infection and can become generalized if immunity is weakened for any reason. Ramsay-Hunt syndrome is a rare manifestation of varicella-zoster virus reactivation. According to Goswami and Gaurkar (2023), it accounts for less than 1 % of cases. The disease is classified as typical or atypical according to the clinical manifestations. We present a rare case of an 87-year-old woman with atypical Ramsay-Hunt syndrome and disseminated herpes zoster. At the initial examination, the only findings were vesicles on the palate and white moss-like lesions on the tongue. The following day, the patient developed right otalgia and herpes zoster was suspected. Antiviral drug administration was initiated immediately. On Day 2 of hospitalization, a disseminated vesicular eruption and right facial nerve paralysis appeared. However, vesicles did not appear in the ear canal or pinna and no vestibulocochlear dysfunction was observed; therefore, we diagnosed atypical Ramsay-Hunt syndrome with disseminated herpes zoster. The rash and right facial nerve paralysis persisted. Herpes zoster, even if confined to oral mucosa, is an important sign that should raise suspicion of incomplete Ramsay-Hunt syndrome. Ramsay-Hunt syndrome can cause severe and persistent symptoms; therefore, it should be diagnosed and treated as early as possible.</div></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":"37 5","pages":"Pages 1056-1062"},"PeriodicalIF":0.4,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144654128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A case of evaluation of the bony beam structure in a patient with skeletal mandibular prognathism with X-linked hypophosphatemic rickets treated with surgical orthodontic treatment 颌骨前突合并x连锁低磷血症佝偻病经外科正畸治疗后骨梁结构评价一例

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Journal of Oral and Maxillofacial Surgery Medicine and Pathology Pub Date : 2025-02-12 DOI: 10.1016/j.ajoms.2025.02.004

Sayoko Nagai , Teruhide Hoshino , Shuji Yoshida , Akira Watanabe , Akira Katakura

{"title":"A case of evaluation of the bony beam structure in a patient with skeletal mandibular prognathism with X-linked hypophosphatemic rickets treated with surgical orthodontic treatment","authors":"Sayoko Nagai , Teruhide Hoshino , Shuji Yoshida , Akira Watanabe , Akira Katakura","doi":"10.1016/j.ajoms.2025.02.004","DOIUrl":"10.1016/j.ajoms.2025.02.004","url":null,"abstract":"<div><div>X-linked hypophosphatemic rickets (XLH) is a rare disease with an estimated annual incidence of 117 cases (95 % CI 75–160) in Japan. It is a disease characterized by bone calcification disorders and bone deformities. We report a case of skeletal mandibular prognathism with XLH. The patient is a 24-year-old man. He visited the near dentistry with the complaint of opposite occlusion, and was referred to our department in April 2015 for the purpose of detailed examination and treatment due to skeletal mandibular prognathism. He had a history of XLH, depression, and a fracture of the right articulatio coxae in 2012, and his orthopedic surgeon reported that it took a long time to heal the bone. Therefore, it was necessary to carefully examine and consider the risk of intraoperative abnormal fractures and postoperative bone healing during surgical orthodontic treatment. In January 2018, the sagittal split ramus osteotomy (SSRO) was performed. As he was progressed favourably, we removed plates and performed genioplasty in February 2019. In order to understand the preoperative bone morphology and evaluate the postoperative bone healing, CT was taken and the trabecular microstructure parameters were analyzed with bone analysis software (TRI / 3D-BON). The operation was completed smoothly without any abnormal fracture during the operation, and the progress is good without delaying the postoperative bone healing. We were evaluating objectively bone quality with CT and were able to evaluate the healing condition.</div></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":"37 5","pages":"Pages 966-972"},"PeriodicalIF":0.4,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144654281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relationship of preoperative serum data with MRONJ patient postoperative course – Retrospective study 术前血清数据与MRONJ患者术后病程的关系-回顾性研究

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Journal of Oral and Maxillofacial Surgery Medicine and Pathology Pub Date : 2025-02-12 DOI: 10.1016/j.ajoms.2025.02.006

Yuri Takeda, Yushi Ezoe, Yuka Iwamae, Tai Kimura, Kenya Tomitsuka, Shinki Koyama, Kazuhiro Imoto, Hiromitsu Morishima, Shinnosuke Nogami, Kensuke Yamauchi

{"title":"Relationship of preoperative serum data with MRONJ patient postoperative course – Retrospective study","authors":"Yuri Takeda, Yushi Ezoe, Yuka Iwamae, Tai Kimura, Kenya Tomitsuka, Shinki Koyama, Kazuhiro Imoto, Hiromitsu Morishima, Shinnosuke Nogami, Kensuke Yamauchi","doi":"10.1016/j.ajoms.2025.02.006","DOIUrl":"10.1016/j.ajoms.2025.02.006","url":null,"abstract":"<div><h3>Objectives</h3><div>The purpose of this study was to clarify prognostic factors indicating the postoperative course following surgical treatment for medication-related osteonecrosis of the jaw (MRONJ).</div></div><div><h3>Materials and methods</h3><div>This was a retrospective investigation of postoperative results of patients who underwent surgical treatment for MRONJ at Tohoku University Hospital. Predictor variables including preoperative serum data, i.e., leukocyte, neutrophil, lymphocyte, platelet, and monocyte counts, neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), lymphocyte to monocyte ratio (LMR), C-reactive protein (CRP), albumin, and total protein (TP), were compared. Postoperative outcomes were categorized as good or poor prognosis, and serum data for each group were compared.</div></div><div><h3>Results</h3><div>The study sample included 35 MRONJ patients, with 16 in the good prognosis and 19 in the poor prognosis group. In the good prognosis group, lymphocyte number and LMR were significantly higher, while NLR and PLR were significantly lower as compared with the poor prognosis group. Significant differences for LMR, NLR, and PLR were mainly due to differences in lymphocyte count, while no significant differences were seen regarding neutrophils, platelets, monocytes, CRP, TP, or albumin.</div></div><div><h3>Conclusions</h3><div>In patients with poor postoperative MRONJ, preoperative findings showed a decrease in lymphocytes. The relationship of preoperative lymphocyte count with postoperative outcome following MRONJ may be useful for clarifying the pathogenesis of MRONJ.</div></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":"37 5","pages":"Pages 1033-1037"},"PeriodicalIF":0.4,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144654124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Interventions for managing oral submucous fibrosis – Commentary to a systematic review 治疗口腔黏膜下纤维化的干预措施-系统综述评论

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Journal of Oral and Maxillofacial Surgery Medicine and Pathology Pub Date : 2025-02-11 DOI: 10.1016/j.ajoms.2025.02.005

Stella Stasiak , Tiffany Li , Adam Jones , Joshua A. Twigg

{"title":"Interventions for managing oral submucous fibrosis – Commentary to a systematic review","authors":"Stella Stasiak , Tiffany Li , Adam Jones , Joshua A. Twigg","doi":"10.1016/j.ajoms.2025.02.005","DOIUrl":"10.1016/j.ajoms.2025.02.005","url":null,"abstract":"<div><div>Oral submucous fibrosis (OSMF) is a chronic, debilitating condition characterized by fibrosis of the oral mucosa, leading to restricted mouth opening, impaired chewing, and speech difficulties. Although its exact causes are not fully understood, factors such as betel nut chewing, nutritional deficiencies, genetic predisposition, and consumption of spicy foods are thought to contribute. A recent update by Jones et al. (2023) [1] of the Cochrane Review titled “Interventions for managing oral submucous fibrosis” included 30 randomised controlled trials (RCTs), with 28 added since the initial 2008 review.</div><div>The primary focus was on evaluating patient-reported outcomes (PROs) for managing OSMF, such as improvements in eating, chewing, and speech. However, only four studies measured these outcomes; most focused on inter-incisal distance and burning sensation intensity. Moderate-certainty evidence showed that antioxidants improved these parameters, but no other interventions demonstrated consistent benefits compared to non-active controls.</div><div>Adverse effects were reported in half of the studies, with poor reporting of participant demographics and limited use of rigorous methodologies, such as proper blinding and allocation concealment. Additionally, surgical interventions, evaluated in four studies, posed high complication risks.</div><div>The review underscores the urgent need for robust research to better understand OSMF pathogenesis and identify effective interventions. Standardising trial designs, prioritising PROs alongside objective measures, and conducting preclinical studies to explore mechanisms of action are critical. Furthermore, prevention through education and cultural shifts away from areca nut use remains essential in reducing the burden of OSMF globally.</div></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":"37 5","pages":"Pages 1086-1088"},"PeriodicalIF":0.4,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144654070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0