Journal of Oral and Maxillofacial Surgery Medicine and Pathology最新文献

{"title":"Human papillomavirus infection status and p53 expression association with survival in Indonesian oral squamous cell carcinoma patients","authors":"Nur Rahadiani ,&nbsp;Sarwanti ,&nbsp;Diani Kartini ,&nbsp;Diah Rini Handjari ,&nbsp;Marini Stephanie ,&nbsp;Ening Krisnuhoni","doi":"10.1016/j.ajoms.2025.02.008","DOIUrl":"10.1016/j.ajoms.2025.02.008","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to analyze the status of human papillomavirus (HPV) infection status and p53 expression in Indonesian patients with oral squamous cell carcinoma (OSCC) and their relationship with patient survival.</div></div><div><h3>Methods</h3><div>This retrospective cohort study was conducted in Indonesia’s main referral hospital with 74 patients diagnosed with OSCC between January 2014 and December 2018. Polymerase chain reaction followed by hybridization was performed to detect HPV genotypes in tumor tissues. The expression of p53 was assessed by immunohistochemistry. Clinicopathological data were collected and patients were followed up for a minimum of 36 months from the month of diagnosis. Statistical tests and survival analyses were also performed.</div></div><div><h3>Results</h3><div>HPV infection was identified in 52 (70.3 %) patients, mostly out-panel genotypes of HPV followed by HPV35. There were no differences in the clinicopathological characteristics between HPV-positive and HPV-negative patients. Positive p53 expression was observed in 47 (63.5 %) patients. The p53-negative patients were significantly younger than the p53-positive patients. No difference in 3-year overall survival was observed between patients with OSCC stratified by HPV infection status and p53 expression. Univariate and multivariate analyses showed that HPV infection status and p53 expression did not correlate with survival.</div></div><div><h3>Conclusion</h3><div>HPV infection and p53 expression were not suitable as prognostic markers for survival in our patients due to the lack of significant associations.</div></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":"37 5","pages":"Pages 1096-1102"},"PeriodicalIF":0.4,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144654026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sclerosing odontogenic carcinoma with fibro-osseous components and delayed multiple spinal metastasis: A case report","authors":"Makiko Tanakura ,&nbsp;Manabu Shigeoka ,&nbsp;Daisuke Takeda ,&nbsp;Naoe Jimbo ,&nbsp;Chihoko Ikeda ,&nbsp;Kousuke Matsumoto ,&nbsp;Junichiro Takeuchi ,&nbsp;Tsutomu Minamikawa ,&nbsp;Masaya Akashi","doi":"10.1016/j.ajoms.2025.02.001","DOIUrl":"10.1016/j.ajoms.2025.02.001","url":null,"abstract":"<div><div>Sclerosing odontogenic carcinoma (SOC) is a very rare tumor that was newly listed in the 2017 World Health Organization (WHO) classification of head and neck tumors. The latest WHO classification includes the lack of metastatic potential and hard tissue formation to the “Definition” and “Histopathology.” Although SOC has been believed a low-grade odontogenic carcinoma, two previous studies describing SOC’s metastatic potential have been published in English. We herein show a case of SOC with both fibro-osseous components and distal metastasis. The patient was a 55-year-old Japanese male whose right mandible had a mass that had been causing him discomfort for a long period. Radiographic features showed a diffuse and borderless lesion in the right mandible. Based on a preoperative local biopsy, fibrous dysplasia was diagnosed. A surgical specimen from the subsequent excision revealed odontogenic carcinoma with fibro-osseous components. A final diagnosis of SOC was made 2 months after the first excision, after an additional segmental resection of mandible was examined. Unexpectedly, multiple spinal metastases occurred 7 years after surgery, and these metastases were excellently cured by radiation therapy. Herein, we outline the case details and tips for the accurate diagnosis and treatment of SOC based on the presentation of its uncommon histological pattern.</div></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":"37 5","pages":"Pages 947-956"},"PeriodicalIF":0.4,"publicationDate":"2025-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144654278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case of improvement of restricted mouth opening caused by buccal mucosa scar using nasolabial flap","authors":"Arun Kumar Mahat ,&nbsp;Ayaka Abe ,&nbsp;Kana Kuribayashi ,&nbsp;Kenji Kawano","doi":"10.1016/j.ajoms.2025.02.003","DOIUrl":"10.1016/j.ajoms.2025.02.003","url":null,"abstract":"<div><div>Restricted mouth opening after oral cancer treatment is a secondary complication caused by scarring of leading to difficulty in eating, chewing, swallowing, breathing and speaking; resulting in poor oral health with psychological difficulties and negative impact on Quality of Life (QoL). There is no specific treatment for trismus and current strategies emphasize on prevention using conservative therapy and surgical resection of scar tissues with reconstruction in cases where conservative therapy is inadequate. Despite the availability of plethora of reconstructive options nasolabial flap with its robust blood supply based on facial artery and proximity to oral cavity requires simpler surgical technique, less time for flap harvest and inset; has improved success rate and is versatile enough to cover both small and large defect with scars that are often well-concealed within the natural nasolabial fold. Herein, we present a case of restricted mouth opening caused by buccal mucosa scar contracture following resection of malignant tumor. The patient underwent surgical resection of scar tissue and a single step technique nasolabial flap reconstruction demonstrating a successful outcome.</div></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":"37 5","pages":"Pages 962-965"},"PeriodicalIF":0.4,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144654280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case of orthognathic surgery for skeletal open bite with Noonan syndrome (NS)","authors":"Kyosuke Okuyama ,&nbsp;Shizu Saito ,&nbsp;Hikari Suzuki ,&nbsp;Yushi Ezoe ,&nbsp;Shinnosuke Nogami ,&nbsp;Kensuke Yamauchi","doi":"10.1016/j.ajoms.2025.02.002","DOIUrl":"10.1016/j.ajoms.2025.02.002","url":null,"abstract":"<div><div>Noonan syndrome (NS) is an autosomal dominant genetic disorder characterized by congenital abnormalities of genes involved in the intracellular Ras/MAPK signalling system. Affected individuals generally show characteristic facial features and short stature, as well as congenital heart disease, thoracic anomalies, lymphangiogenesis, and bleeding tendency. Reported here is a case of orthognathic jaw surgery performed for a 29-year-old woman with such characteristic facial features and skeletal open bite. The patient was determined to be suitable for orthognathic treatment, and examined for cardiac disease associated with NS and ability to tolerate surgery before undergoing preoperative orthodontic treatment. Le Fort I osteotomy and bilateral sagittal splitting ramus osteotomy procedures were performed under general anaesthesia. Preoperative screening revealed that platelet count and prothrombin time were normal, with only a slight increase in activated partial thromboplastin time, though the actual amount of blood loss was high at 1442 ml. While the cause of bleeding tendency associated with NS is unknown, preoperative determination of coagulation factors and platelet function, as well as screening are considered to be essential. For the present case, a bilateral sagittal splitting ramus osteotomy procedure was selected. On the other hand, because an intraoral vertical ramus osteotomy (IVRO) results in less blood loss, careful consideration should be given when choosing an orthognathic surgery technique for NS patients, such as osteotomy of the maxilla or mandible alone, or IVRO only on the side where the mandible is moved backward in cases with an asymmetrical skeletal structure.</div></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":"37 5","pages":"Pages 957-961"},"PeriodicalIF":0.4,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144654279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of smoking on the expression of SARS-CoV-2 infection-related molecules in the oral mucosa","authors":"Toshio Yudo ,&nbsp;Reiko Tokuyama-Toda ,&nbsp;Shinji Ide ,&nbsp;Yusuke Takebe ,&nbsp;Mai Takeshita-Umehara ,&nbsp;Kohei Ijichi ,&nbsp;Misao Ishikawa ,&nbsp;Kazuhito Satomura","doi":"10.1016/j.ajoms.2025.01.016","DOIUrl":"10.1016/j.ajoms.2025.01.016","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to investigate whether various SARS-CoV-2 infection-related molecules, including ACE2, are expressed in oral tissues and clarify the effects of smoking on these.</div></div><div><h3>Methods</h3><div>The expressions of the SARS-CoV-2 infection-related molecules ACE2, NRP-1, TMPRSS, and Furin in normal oral mucosa and salivary gland tissues were immunohistochemically examined. This study also investigated the expression of SARS-CoV-2 infection-related molecules when cigarette smoke extract (CSE) was applied to oral mucosal epithelial cells in vitro and examined differences in the expression of these molecules at the mRNA and protein levels in the oral tissues of smokers and nonsmokers.</div></div><div><h3>Results</h3><div>The expression of ACE2, NRP-1, TMPRSS2, and Furin was observed in the oral mucosal tissues and salivary gland tissues. When oral mucosal epithelial cells were exposed to CSE, the mRNA expression of ACE2 and Furin increased in a dose- and time-dependent manner, whereas the expression of NRP-1 increased up to 1 % CSE but decreased to 5 % CSE. In terms of protein expression, only NRP-1 increased up to 1 % CSE, as did its mRNA. The expression of these molecules in the oral mucosal tissues of smokers and nonsmokers tended to be higher in smokers; however, the difference was not significant.</div></div><div><h3>Conclusions</h3><div>This study revealed that the SARS-CoV-2 infection-related molecules ACE2, NRP-1, TMPRSS, and Furin are expressed in the oral mucosa and salivary gland tissue. These molecules may be affected by smoking and indicate the importance of oral health and are thought to be one of the scientific grounds for future antismoking campaigns.</div></div><div><h3>Data Availability Statement</h3><div>The data that support the findings of this study are available from the corresponding author upon reasonable request.</div></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":"37 4","pages":"Pages 778-787"},"PeriodicalIF":0.4,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144222225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Orthokeratinised odontogenic cyst of the anterior mandible: A case report","authors":"Yukio Yamano ,&nbsp;Shin Takeuchi ,&nbsp;Ayumi Yamamoto ,&nbsp;Tamon Narukawa ,&nbsp;Shuko Koide ,&nbsp;Masumi Igari","doi":"10.1016/j.ajoms.2025.01.017","DOIUrl":"10.1016/j.ajoms.2025.01.017","url":null,"abstract":"<div><div>The orthokeratinized odontogenic cyst (OOC) is a rare developmental odontogenic cyst of the jaws, which is lined by stratified squamous epithelium. These slowly growing cysts are painless and often detected incidentally during radiographic investigations. The OOC occurs over a broad age range, with a predilection for the third and fourth decades of life. Previous studies have reported that the OOC occurs more frequently in male patients. The molar and ramus regions of the mandible are the more commonly involved sites. The radiographic features of periapical OOCs are similar to those of other unilocular cysts and are difficult to differentiate. The prognosis after enucleation is very good, with a low recurrence rate. Here, we describe an uncommon case of an OOC located in the anterior mandible. The patient was a 16-year-old adolescent, who was referred to our department for further evaluation of a radiolucent periapical lesion in the anterior mandible. Based on clinical findings, a biopsy was performed for a tentative diagnosis. With the patient under general anesthesia, the cyst was subsequently resected. Histologically, the cyst wall was lined by keratinizing stratified squamous epithelium and included a granular cell layer. The cystic lumen was filled with laminated keratin debris. The findings were diagnosed as an OOC. No recurrences or postoperative complications have been noted over a 42-month period. Although the occurrence of OOC in the anterior mandible is rare, it should be included in the differential diagnosis along with other radiolucent lesions of the jaw.</div></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":"37 4","pages":"Pages 849-853"},"PeriodicalIF":0.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144221562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical outcomes of 6-mm implants compared with 10-mm implants in Japanese patients: A retrospective study","authors":"Tomoki Hirano ,&nbsp;Masashi Motegi ,&nbsp;Yoshitaka Furuya ,&nbsp;Taichi Ito ,&nbsp;Hideshi Sekine ,&nbsp;Hodaka Sasaki","doi":"10.1016/j.ajoms.2025.01.014","DOIUrl":"10.1016/j.ajoms.2025.01.014","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to compare the clinical outcomes of 6-mm implants with those of 10-mm implants in Japanese patients, particularly on cumulative survival rates and associated risk factors.</div></div><div><h3>Methods</h3><div>This study included patients from Tokyo Dental College Suidobashi Hospital who received 6-mm implants from January 2014 to August 2020 and 10-mm implants from January 2014 to December 2016. Data collection continued until August 2021. Patient demographics, implant locations, implant widths, cumulative survival rates, and conditions of lost implants were also analyzed.</div></div><div><h3>Results</h3><div>A total of 69 patients received 95 6-mm implants, and 416 patients received 607 10-mm implants. The cumulative survival rate up to 7 years was 94.0 % for patients who received 6-mm implants and 98.8 % for patients who received 10-mm implants, indicating a significantly lower survival rate for patients with shorter implants. The hazard ratio for implant loss was 4.07, indicating a higher risk among patients with 6-mm implants. Most failures in the 6-mm implant group occurred postprosthetic placement, particularly in the maxillary molar region, whereas most 10-mm implant losses occurred prerestoration.</div></div><div><h3>Conclusions</h3><div>Although 6-mm implants have a slightly lower cumulative survival rate compared with 10-mm implants, they are a viable alternative to bone augmentation. Therefore, careful consideration of patient-specific factors such as bone quality and occlusal forces is crucial, particularly in the maxillary molar region. Furthermore, long-term studies and investigation of the risk factors are necessary to optimize treatment planning for short implants.</div></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":"37 4","pages":"Pages 677-682"},"PeriodicalIF":0.4,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144222193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case of shot for botulinum toxin as an adjuvant in the treatment of complications after mechanical chin liposuction","authors":"Letícia Laura Martinez ,&nbsp;Juliana Aparecida Jellmayer ,&nbsp;Camilla Beatriz Pallone ,&nbsp;Bianca Pires Nepomuceno ,&nbsp;Pâmela Letícia Santos ,&nbsp;Thallita Pereira Queiroz","doi":"10.1016/j.ajoms.2025.01.015","DOIUrl":"10.1016/j.ajoms.2025.01.015","url":null,"abstract":"<div><div>To report a clinical case of facial paralysis treatment following mechanical liposuction of submental fat, using low-level laser therapy (LLLT), botulinum toxin (BT), and ozone therapy (OZ), addressing the factors involved in nerve regeneration and muscle tone. For this, a 40-year-old female patient presented with the main complaint of facial asymmetry after mechanical liposuction of submental fat. The proposed treatment included the application of LLLT and OZ to stimulate the regeneration of the involved nerve, and BT to reduce asymmetry by following the pattern of muscle contractions. The patient was re-evaluated 30 days after the BT application, showing satisfactory results. Thus, it was possible to conclude the combined application of low-level laser therapy and ozone therapy played a fundamental role in the recovery of facial paralysis resulting from mechanical liposuction of submental fat. Additionally, botulinum toxin contributed to the correction of facial asymmetries and consequently improved facial aesthetics, restoring the patient's self-esteem.</div></div><div><h3>Level of Evidence</h3><div>Level IV, case study.</div></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":"37 4","pages":"Pages 800-803"},"PeriodicalIF":0.4,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144221608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multicenter prospective study on the incidence and cure rates of medication-related osteonecrosis of the jaw (complete translation)","authors":"Masaki Fujimori ,&nbsp;Yoshiyuki Toriyabe ,&nbsp;Nobuhiro Kaku ,&nbsp;Kosuke Shimazaki ,&nbsp;Toyonori Suzuki ,&nbsp;Takahiro Abe ,&nbsp;Akihiro Tanimura ,&nbsp;Akihiro Kudou ,&nbsp;Masaki Donen ,&nbsp;Yasushi Kawaguchi ,&nbsp;Noriyuki Sakakibara ,&nbsp;Masanori Nojima ,&nbsp;Shujiroh Makino","doi":"10.1016/j.ajoms.2025.01.011","DOIUrl":"10.1016/j.ajoms.2025.01.011","url":null,"abstract":"<div><h3>Objective</h3><div>To ascertain incidence and cure rates of medication-related and -unrelated osteonecrosis of the jaw (MRONJ and MUONJ, respectively).</div></div><div><h3>Methods</h3><div>Between October 1, 2013, and September 30, 2016, we enrolled participants from eight advanced dental-care institutions, undertook a secondary partial analysis of a Hokkaido Association of Hospital Dentistry multicenter prospective MRONJ study, and surveyed the prescription numbers and bone-modifying agent (BMA) types dispensed in all 574 medical institutions in Eastern Hokkaido to calculate the MRONJ and MUONJ incidence and cure rates.</div></div><div><h3>Results</h3><div>Among 85 ONJ cases, 39, 29, 5, 3, and 9 participants had low-dose bisphosphonate-related ONJ (BRONJ), high-dose BRONJ, low-dose denosumab-related ONJ (DRONJ), high-dose DRONJ, and MUONJ, respectively. The BMA prescription survey [response rate: 96.3 % (553/574)] showed high-dose bisphosphonates, low-dose denosumab (Dmab), and high-dose Dmab accounted for 5778 (1781 patients), 9787 (3756 patients), and 3268 (986 patients) prescriptions, respectively. During the 3-year study period, the estimated incidences of MRONJ due to low-dose BRONJ, high-dose BRONJ, low-dose DRONJ, high-dose DRONJ, and MUONJ were 0.104 %, 1.623 %, 0.133 %, 0.304 %, and 0.0004 %, respectively. The 12-month MUONJ cumulative cure rate was 100 %; cumulative cure rates for low-dose MRONJ were 46.5 %, 71.2 %, and 85.6 % at 12, 24, and 36 months, respectively; and those for high-dose MRONJ were 0 % at 12 months and 30.0 % at 24 and 36 months. The three groups showed significant differences (<em>p</em> &lt; 0.001).</div></div><div><h3>Conclusions</h3><div>The general population incidence of MRONJ was higher than that of MUONJ, with significant differences in cumulative cure rates for MUONJ, low-dose MRONJ, and high-dose MRONJ.</div></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":"37 4","pages":"Pages 765-777"},"PeriodicalIF":0.4,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144222114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case of extracranial internal carotid artery aneurysm with massive bleeding from the oral cavity","authors":"Kiyosato Hino ,&nbsp;Shogo Kikuta ,&nbsp;Yushi Abe ,&nbsp;Hidetoshi Nomura ,&nbsp;Jin Kikuchi ,&nbsp;Kimihiko Orito ,&nbsp;Makoto Hoshino ,&nbsp;Motohiro Morioka ,&nbsp;Jingo Kusukawa","doi":"10.1016/j.ajoms.2025.01.010","DOIUrl":"10.1016/j.ajoms.2025.01.010","url":null,"abstract":"<div><div>Extracranial internal carotid artery aneurysm (EICA) is a rare disease that accounts for less than 1 % of all aneurysms. The most common cause of EICA is arteriosclerosis, and some aneurysms that occur in the neck or tonsils exhibit dysphagia and pulsatile mass formation. In this report, we describe a case of EICA in an 84-year-old woman who presented with massive intraoral bleeding due to a denture ulcer. The patient with multiple medical histories, was rushed to the hospital due to recurrent bleeding from oral cavity. This patient was treated with coil embolization to stop the bleeding, and was discharged from the hospital 1 month after the surgery without any sequelae. Although rupture of an EICA is considered rare, when it does, it can cause massive bleeding and even death. Therefore, it is important to differentiate EICA that appears in the oral cavity from tonsillar abscesses and benign tumors.</div></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":"37 4","pages":"Pages 724-728"},"PeriodicalIF":0.4,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144222200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}