Journal of Oral and Maxillofacial Surgery Medicine and Pathology最新文献_第8页

Dentoalveolar distraction osteogenesis combined with surgical orthodonthic treatment for a patient with jaw deformity and ankylosed maxillary canine – A case report 牙槽骨牵引成骨联合外科正畸治疗一名下颌畸形和上颌犬牙强直的患者--病例报告

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Journal of Oral and Maxillofacial Surgery Medicine and Pathology Pub Date : 2024-06-24 DOI: 10.1016/j.ajoms.2024.06.007

Zhuoyang Zheng, Ryoko Takeuchi, Daisuke Suda, Daisuke Saito, Daichi Hasebe, Tadaharu Kobayashi

{"title":"Dentoalveolar distraction osteogenesis combined with surgical orthodonthic treatment for a patient with jaw deformity and ankylosed maxillary canine – A case report","authors":"Zhuoyang Zheng, Ryoko Takeuchi, Daisuke Suda, Daisuke Saito, Daichi Hasebe, Tadaharu Kobayashi","doi":"10.1016/j.ajoms.2024.06.007","DOIUrl":"10.1016/j.ajoms.2024.06.007","url":null,"abstract":"<div><div>In surgical orthodontic treatment, the presence of an ankylosed tooth makes it difficult to achieve the desired dental arch morphology. Single tooth osteotomy and dentoalveolar distraction osteogenesis (DO) combined with surgical orthodontic treatment for a patient with jaw deformity and an ankylosed maxillary canine is described in this report. A 37-year-old female was referred to our clinic with a chief complaint of anterior crossbite and was diagnosed with skeletal mandibular protrusion. During preoperative orthodontic treatment for surgical orthodontic treatment, her upper right canine did not move and was diagnosed as an ankylosed tooth. Therefore, we decided to perform a single tooth osteotomy and dentoalveolar DO of the right maxillary canine. Instead of using a commercially available distractor, the dentoalveolar DO in this case was performed using a homemade device with orthodontic biomechanics to move the ankylosed tooth with its supporting alveolar bone and soft tissue into the correct position. After preoperative orthodontic treatment, orthognathic surgery with Le Fort I osteotomy and bilateral sagittal split osteotomies was performed. However, root resorption of the right upper canine continued, and the resorption area was therefore restored with composite resin 10 months after orthognathic surgery to improve the function and esthetics of the maxillofacial region. One and a half years have passed since the orthognathic surgery, and the skeletal stability is good, and the patient is progressing well.</div></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":"37 1","pages":"Pages 130-134"},"PeriodicalIF":0.4,"publicationDate":"2024-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142660501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cytokeratin 19 a potential biomarker for circulating tumor cells in oral tongue squamous cell carcinoma 细胞角蛋白19：口腔舌鳞状细胞癌循环肿瘤细胞的潜在生物标志物

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Journal of Oral and Maxillofacial Surgery Medicine and Pathology Pub Date : 2024-06-24 DOI: 10.1016/j.ajoms.2024.06.006

Noble T. Baby , Shaji Thomas , R. Rejnish Kumar , Jayasree Kattoor , S. Kannan

{"title":"Cytokeratin 19 a potential biomarker for circulating tumor cells in oral tongue squamous cell carcinoma","authors":"Noble T. Baby , Shaji Thomas , R. Rejnish Kumar , Jayasree Kattoor , S. Kannan","doi":"10.1016/j.ajoms.2024.06.006","DOIUrl":"10.1016/j.ajoms.2024.06.006","url":null,"abstract":"<div><h3>Objective</h3><div><span><span><span>Oral tongue squamous cell carcinoma is one of the most common cancers in the </span>oral cavity. The lack of a signature biomarker to assess the treatment response makes the </span>overall survival<span> rate still less. Cytokeratins are </span></span>intermediate filaments<span><span> of the cytoskeleton<span><span> and shown to be used as a marker to detect circulating tumor cells (CTC) of different </span>carcinomas. The present study aims to evaluate the potential of </span></span>cytokeratin 19<span> (CK19) as a marker for CTC in oral tongue squamous cell carcinoma (OTC) patients.</span></span></div></div><div><h3>Methods</h3><div>The expression pattern of CK19 was assessed in peripheral blood mononuclear cells (PBMC) of OTC patients by real-time polymerase chain reaction (RT-PCR) and correlated to various clinico-pathological parameters of patients. The association between various clinico-pathological parameters and the expression of CK19 was evaluated by the Chi-Square Test.</div></div><div><h3>Results</h3><div>The results suggest that CK19 mRNA level is significantly associated with the clinical stage (P = 0.021) and nodal status (P = 0.011) of patients. Also, a significant association is observed with overall survival (P = 0.017) of the patients with CK19 expression.</div></div><div><h3>Conclusion</h3><div>The CK19 mRNA expression pattern in peripheral blood may be useful for CTCs monitoring and can be used as a prognostic biomarker for OTC patients.</div></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":"37 2","pages":"Pages 272-277"},"PeriodicalIF":0.4,"publicationDate":"2024-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143150356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinicopathological study on diameter of extranodal extension of cervical metastatic lymph nodes in the prognosis of oral cancer 口腔癌预后中宫颈转移淋巴结外延直径的临床病理学研究

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Journal of Oral and Maxillofacial Surgery Medicine and Pathology Pub Date : 2024-06-21 DOI: 10.1016/j.ajoms.2024.06.008

Daigo Yoshiga , Naomi Yada , Kazuya Haraguchi , Hironori Fujita , Kenichiro Katsuno , Sho Mitsugi , Norihiko Furuta , Manabu Habu , Masaaki Sasaguri , Kazuhiro Tominaga , Izumi Yoshioka

{"title":"Clinicopathological study on diameter of extranodal extension of cervical metastatic lymph nodes in the prognosis of oral cancer","authors":"Daigo Yoshiga , Naomi Yada , Kazuya Haraguchi , Hironori Fujita , Kenichiro Katsuno , Sho Mitsugi , Norihiko Furuta , Manabu Habu , Masaaki Sasaguri , Kazuhiro Tominaga , Izumi Yoshioka","doi":"10.1016/j.ajoms.2024.06.008","DOIUrl":"10.1016/j.ajoms.2024.06.008","url":null,"abstract":"<div><h3>Objectives</h3><div>To investigate the relationship between the degree of destruction of the cervical lymph node capsule, extranodal invasion distance, and the prognosis of extranodal extension (ENE)-positive patients</div></div><div><h3>Study design</h3><div>We retrospectively examined microscopic slides from neck dissection specimens of ENE-positive patients of our hospital. The ENE distance was measured by a pathologist who set up a virtual lymph node and measured the maximum extranodal invasion distance. The maximum distance was used for multiple ENEs. Forty patients with ENE were enrolled in this study. The Kaplan–Meier method was used to estimate survival.</div></div><div><h3>Results</h3><div>Among the ENE-positive cases, the capsule was completely destroyed and partially destroyed in seven and 33 cases, respectively. Disease-specific survival (DSS) was 1251 days (range 156–3009 days). The median distance of extranodal invasion was 2500 µm (392–8500 µm) in the 33 ENE-positive cases in which the capsule was not completely destroyed. Receiver operating characteristic curve analysis of these 33 cases showed that the cutoff value of extranodal invasion distance for progression-free survival was 2241 µm.</div></div><div><h3>Conclusions</h3><div>ENE is a prognostic predictor of oral cancer; ENE was an independent prognostic factor; and ENE size cutoff of 2241 µm was a significant prognostic factor.</div></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":"37 1","pages":"Pages 64-69"},"PeriodicalIF":0.4,"publicationDate":"2024-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142660247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Maxillary osteonecrosis related to post-COVID-19: A report of case series and 6-month follow-up 与后COVID-19相关的上颌骨骨坏死：系列病例和 6 个月随访报告

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Journal of Oral and Maxillofacial Surgery Medicine and Pathology Pub Date : 2024-06-18 DOI: 10.1016/j.ajoms.2024.06.005

Duong Van Huynh , Dung Kim Nguyen , Tuan Van Nguyen , Thanh Van Bui , Chanh Trung Le

{"title":"Maxillary osteonecrosis related to post-COVID-19: A report of case series and 6-month follow-up","authors":"Duong Van Huynh , Dung Kim Nguyen , Tuan Van Nguyen , Thanh Van Bui , Chanh Trung Le","doi":"10.1016/j.ajoms.2024.06.005","DOIUrl":"10.1016/j.ajoms.2024.06.005","url":null,"abstract":"<div><h3>Objective</h3><div>Post-COVID-19-related osteonecrosis of jaws (PCRONJ) has emerged as a complication observed in patients recovered from COVID-19 infection, but PCRONJ has been understudied in the literature. We aimed to report a case series of PCRONJ, including diagnosis, treatment procedures, and discussion about related factors.</div></div><div><h3>Methods</h3><div>We prospectively evaluated PCRONJ patients at the National Hospital of Odonto-Stomatology in Ho Chi Minh, Vietnam. Patients’ demographics, medical history, COVID-19 treatment, clinical and preclinical features, and clinical outcomes were reported.</div></div><div><h3>Results</h3><div>During a six-month period, nine patients were included in this study. The mean age was 53.7 years and 56 % of patients were male. All patients were diagnosed with PCRONJ at the maxillary, diabetic and administered corticosteroids to manage COVID-19 prior to this infection. The mean time from COVID-19 recovery to the onset of symptoms was 4.6 weeks. 89 % of patients underwent tooth extractions following tooth mobility examination. Clinically, mobility of dentoalveolar maxillae, in combination with necrotic bone exposure and/or inflammatory signs were observed in all cases. Radiographically, bone destruction located in maxillae and surrounding structures reflected the extension of lesions. Surgical treatment was applied for all cases to debride the necrotic bone. All patients exhibited well-healing, and an improved quality of life after discharge.</div></div><div><h3>Conclusions</h3><div>PCRONJ should be distinguished from other forms of osteonecrosis of the jaws due to its distinct features. Multiple risk factors complicate the refinement of the likelihood of PCRONJ but warrant awareness for clinicians. An early diagnosis would help to plan a timely treatment and for optimal clinical outcomes.</div></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":"37 1","pages":"Pages 180-187"},"PeriodicalIF":0.4,"publicationDate":"2024-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142660504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparative three-dimensional maxillary stability assessment: Bioresorbable miniplate vs. titanium miniplate systems in Le Fort I osteotomy 上颌骨三维稳定性对比评估：勒堡 I 型截骨术中的生物可吸收小板与钛小板系统

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Journal of Oral and Maxillofacial Surgery Medicine and Pathology Pub Date : 2024-06-16 DOI: 10.1016/j.ajoms.2024.06.003

Koki Takamatsu , Sunao Shiogama , Yosuke Ikehata , Arisa Yasuda , Yuji Kurihara , Tatsuo Shirota

{"title":"Comparative three-dimensional maxillary stability assessment: Bioresorbable miniplate vs. titanium miniplate systems in Le Fort I osteotomy","authors":"Koki Takamatsu , Sunao Shiogama , Yosuke Ikehata , Arisa Yasuda , Yuji Kurihara , Tatsuo Shirota","doi":"10.1016/j.ajoms.2024.06.003","DOIUrl":"10.1016/j.ajoms.2024.06.003","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to evaluate the usefulness of bioresorbable miniplates by comparing the three-dimensional maxillary stability of poly L-lactic acid and titanium miniplate systems in Le Fort I osteotomy.</div></div><div><h3>Methods</h3><div>Fifty patients with jaw deformities underwent Le Fort I or bilateral sagittal split osteotomies. The patients were divided into two groups: the first group received the polylactic acid miniplate system for bone fixation, while the second group received the titanium miniplate system. Cone-beam computed tomography (CBCT) was performed before surgery and at 1 and 6 months after surgery. The acquired images were overlapped to quantify the extent of maxillary relapse by calculating the difference in the distance moved between 1 and 6 months after surgery.</div></div><div><h3>Results</h3><div>There was no significant difference in maxillary stability between the two groups 6 months after surgery.</div></div><div><h3>Conclusions</h3><div>The postoperative stability achieved using the poly L-lactic acid miniplate system for maxillary fixation was comparable to that achieved using the titanium miniplate system.</div></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":"37 1","pages":"Pages 56-63"},"PeriodicalIF":0.4,"publicationDate":"2024-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141402553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Segmental mandibular resection and reconstruction using a multidisciplinary approach in adolescent and young adult patients: A case of Ewing sarcoma with a eight-year follow-up 采用多学科方法对青少年和年轻成人患者进行下颌骨节段切除和重建：一例随访八年的尤文肉瘤病例

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Journal of Oral and Maxillofacial Surgery Medicine and Pathology Pub Date : 2024-06-15 DOI: 10.1016/j.ajoms.2024.06.002

Sumitaka Hagiwara , Ikuo Hyodo , Daisuke Nishikawa , Masashi Ando , Naoko Maeda , Shogo Ozawa , Yasuhisa Hasegawa , Nobuhiro Hanai

{"title":"Segmental mandibular resection and reconstruction using a multidisciplinary approach in adolescent and young adult patients: A case of Ewing sarcoma with a eight-year follow-up","authors":"Sumitaka Hagiwara , Ikuo Hyodo , Daisuke Nishikawa , Masashi Ando , Naoko Maeda , Shogo Ozawa , Yasuhisa Hasegawa , Nobuhiro Hanai","doi":"10.1016/j.ajoms.2024.06.002","DOIUrl":"10.1016/j.ajoms.2024.06.002","url":null,"abstract":"<div><div>Ewing sarcoma (ES) is a rare malignant tumor, particularly in the head and neck region. Its incidence tends to be higher in pediatric patients than in adults. Occasionally, curative treatment of ES requires extensive resection of the primary lesion, which can result in postoperative aesthetic or functional disorders. In recent years, advances have been made in reconstructive surgery of the maxillofacial region. Broad mandibular defects are a prime indication for several types of vascularized free bone grafts. Similarly, the treatment of ES has progressed in the field of systemic chemotherapy. We report a multidisciplinary surgical case of ES in the mandible of a 12-year-old patient who underwent extensive mandibular resection and fibula free flap (FFF) reconstruction with preoperative and postoperative chemotherapy. In brief, after conducting a multidisciplinary clinical conference, perioperative chemotherapy was planned by pediatric oncologists, and the operation was performed by a head and neck cancer team consisting of head and neck, oral and maxillofacial, and plastic surgeons. Five months after the operation, prosthodontists applied an intraoral prosthesis. The reconstructed mandible demonstrated good development, and the quality of life was maintained both aesthetically and functionally for eight years after treatment. Our efficient multidisciplinary medical collaboration demonstrated that mandibular reconstruction using FFF is a suitable method for treating pediatric patients and leads to long-term survival with satisfactory outcomes.</div></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":"37 1","pages":"Pages 123-129"},"PeriodicalIF":0.4,"publicationDate":"2024-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141401853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Outcomes of postoperative radiotherapy combined with or without chemotherapy for locally advanced oral cancer: A systematic review and meta-analysis 局部晚期口腔癌术后放疗联合或不联合化疗的疗效：系统综述和荟萃分析

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Journal of Oral and Maxillofacial Surgery Medicine and Pathology Pub Date : 2024-06-14 DOI: 10.1016/j.ajoms.2024.06.001

Hu Longfei, Zhou Shangyin, Zhang Ju

{"title":"Outcomes of postoperative radiotherapy combined with or without chemotherapy for locally advanced oral cancer: A systematic review and meta-analysis","authors":"Hu Longfei, Zhou Shangyin, Zhang Ju","doi":"10.1016/j.ajoms.2024.06.001","DOIUrl":"10.1016/j.ajoms.2024.06.001","url":null,"abstract":"<div><h3>Objective</h3><div>Radiotherapy combined with chemotherapy or radiotherapy alone is an important treatment for locally advanced oral squamous cell carcinoma. We performed a meta-analysis of published reports about these two treatments.</div></div><div><h3>Methods</h3><div>We performed an extensive exploration of various databases, such as Embase, PubMed, and the Cochrane Library. The study included research on the comparison between postoperative chemoradiotherapy (POCRT) and postoperative radiotherapy (PORT) for oral cancer, with a restriction on the search language to English. The included endpoints consisted of disease-free survival (DFS), overall survival (OS), locoregional control (LRC), and distant metastasis-free survival (DMFS).</div></div><div><h3>Results</h3><div>Sixteen studies were included, including 3 prospective studies and 13 retrospective studies, with 3364 patients. For patients with locally advanced oral cancer, compared with PORT, POCRT had better DFS (HR 0.64; 95 % confidence interval [CI],0.48–0.84; P = 0.001), OS (HR 0.76;95 %CI 0.65–0.89; P = 0.0005), and LRC (HR 0.65;95 %CI 0.44–0.95; P = 0.02). There was a tendency for DMFS (RR 0.95;95 %CI 0.90–1.01; P = 0.09) to exhibit a marginal statistical distinction. The risks of grade 3 or higher acute toxicity, such as oral mucositis (RR 1.36; p = 0.44), dysphagia (RR 1.57; p = 0.13), and severe skin (RR 0.71; p = 0.17), were more frequent in the POCRT group, but the difference was not statistically significant.</div></div><div><h3>Conclusions</h3><div>For patients with oral squamous cell carcinoma, POCRT is beneficial in terms of DFS, OS, and LRC, but there is no significant benefit in DMFS. The group receiving POCRT exhibited a slightly increased likelihood of experiencing oral mucositis and dysphagia, although the disparity did not attain statistical significance.</div></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":"37 1","pages":"Pages 141-150"},"PeriodicalIF":0.4,"publicationDate":"2024-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141400183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Atypical radiological presentations of a calcified epithelial odontogenic tumour in the maxilla: A rare case composed of massive calcification 上颌骨钙化上皮性牙源性肿瘤的非典型放射学表现：一例罕见的大量钙化病例

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Journal of Oral and Maxillofacial Surgery Medicine and Pathology Pub Date : 2024-06-13 DOI: 10.1016/j.ajoms.2024.06.004

Norihiko Furuta , Yoshikazu Harada , Aki Miyawaki , Emi Sugiyama , Kazuhiro Tominaga

引用次数: 0

Oncocytic metaplasia as a histopathological feature in a case of inflammatory fibrous hyperplasia: A case report 炎性纤维增生症病例中作为组织病理学特征的肿瘤细胞化生：病例报告

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Journal of Oral and Maxillofacial Surgery Medicine and Pathology Pub Date : 2024-05-31 DOI: 10.1016/j.ajoms.2024.05.007

Brunno Santos de Freitas Silva , Eleazar Mezaiko , Reuber Mendes Rocha , Hélen Kaline Farias Bezerra , Pablo Agustin Vargas , Fernanda Paula Yamamoto-Silva

{"title":"Oncocytic metaplasia as a histopathological feature in a case of inflammatory fibrous hyperplasia: A case report","authors":"Brunno Santos de Freitas Silva , Eleazar Mezaiko , Reuber Mendes Rocha , Hélen Kaline Farias Bezerra , Pablo Agustin Vargas , Fernanda Paula Yamamoto-Silva","doi":"10.1016/j.ajoms.2024.05.007","DOIUrl":"10.1016/j.ajoms.2024.05.007","url":null,"abstract":"<div><div>Oncocytic metaplasia refers to a metaplastic alteration occurring in duct and acinar cells, typically found in major or minor salivary glands, commonly associated with aging. Despite being infrequently reported, it appears to be an underrecognized phenomenon that may be linked to inflammatory fibrous hyperplasia (IFH). A 66-year-old caucasian female, who is a non-smoker and abstains from alcohol, presented with longstanding multiple nodular lesions along the mucosa of the maxillary alveolar ridge. Clinical examination led to a diagnosis of IFH, which was confirmed through excisional biopsies. Histopathological examination revealed characteristic features of IFH alongside ductal structures exhibiting notable cell hyperplasia with oncocytic metaplasia. These cells displayed an irregular arrangement of single and double-layered structures with cystic dilatation. Additionally, some excretory ducts exhibited focal hyperplasia and thickening. This case underscores the co-occurrence of oncocytic metaplasia with IFH, emphasizing the significance for pathologists to identify such features to prevent misdiagnosis and unwarranted investigations.</div></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":"37 1","pages":"Pages 248-250"},"PeriodicalIF":0.4,"publicationDate":"2024-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142660614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Epstein-Barr virus-positive plasmablastic lymphoma in maxillary gingiva of HIV-negative patient – Case report HIV 阴性患者上颚牙龈中的 Epstein-Barr 病毒阳性浆细胞性淋巴瘤 - 病例报告

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Journal of Oral and Maxillofacial Surgery Medicine and Pathology Pub Date : 2024-05-29 DOI: 10.1016/j.ajoms.2024.05.003

Yoshio Otake , Atsumu Kouketsu , Shinnosuke Nogami , Hiroyuki Kumamoto , Tsuyoshi Sugiura , Kensuke Yamauchi

{"title":"Epstein-Barr virus-positive plasmablastic lymphoma in maxillary gingiva of HIV-negative patient – Case report","authors":"Yoshio Otake , Atsumu Kouketsu , Shinnosuke Nogami , Hiroyuki Kumamoto , Tsuyoshi Sugiura , Kensuke Yamauchi","doi":"10.1016/j.ajoms.2024.05.003","DOIUrl":"10.1016/j.ajoms.2024.05.003","url":null,"abstract":"<div><div>Plasmablastic lymphoma (PBL) is a type of non-Hodgkin lymphoma commonly associated with human immunodeficiency virus (HIV) infection. In rare cases, PBL occurrence is noted in the oral cavity of elderly individuals who are HIV negative and EBV positive. The present report describes a case of oral mucosa-type PBL that occurred in the maxillary gingiva of the oral cavity. A 91-year-old male came to our clinic with enlarged swelling of the palatal gingiva of the right maxillary molar. The initial examination showed a smooth-surfaced extraordinary swelling with a diameter of approximately 20 mm. Cytology findings led to a class V determination and the patient was clinically diagnosed with a right-sided maxillary malignant tumor. Imaging studies also revealed a tumor in the right-side submandibular lymph node. For further confirmation of the diagnosis, a tissue biopsy was performed and a diagnosis of PBL determined, based on the histopathological and immunohistological findings of the specimen. Blood test results showed that the patient was HIV negative and EBV positive. Two years after the biopsy, there was no recurrence or enlargement in the affected area noted.</div></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":"37 1","pages":"Pages 215-220"},"PeriodicalIF":0.4,"publicationDate":"2024-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142660613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0