Subgemmal neurogenous plaque and oral squamous cell carcinoma: Association or coincidence?

IF 0.4 Q4 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of Oral and Maxillofacial Surgery Medicine and Pathology Pub Date : 2024-07-06 DOI:10.1016/j.ajoms.2024.07.005

Giovanna Lopes Carvalho , Juliana Mota Siqueira , Daniele Heguedusch , David Eduardo Zuluaga Liberato , Andressa Teruya Ramos , Emília Maria Gomes Aguiar , Fabio Daumas Nunes

{"title":"Subgemmal neurogenous plaque and oral squamous cell carcinoma: Association or coincidence?","authors":"Giovanna Lopes Carvalho , Juliana Mota Siqueira , Daniele Heguedusch , David Eduardo Zuluaga Liberato , Andressa Teruya Ramos , Emília Maria Gomes Aguiar , Fabio Daumas Nunes","doi":"10.1016/j.ajoms.2024.07.005","DOIUrl":null,"url":null,"abstract":"<div><div>Oral squamous cell carcinoma (OSCC) is a differential diagnosis of subgemmal neurogenous plaque (SNP), however cases of both adjacent lesions is extremely rare. Usually, SNP is associated with severe and persistent pain, a symptom rarely seen in early-stage OSCC. Here, we present a 47-year-old female patient complaining of severe pain upon touch, eating, or drinking in the posterior third of the lateral border of the tongue for one year, which was diagnosed as SNP. However, the symptoms did not decrease, and changed location to the middle third of the lateral border of the tongue, together with the appearance of a new lesion, which was diagnosed as OSCC. While the simultaneous occurrence of OSCC and SNP in the oral cavity is uncommon, pain has been reported as the initial symptom of malignancy in such cases.</div></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":"37 2","pages":"Pages 376-379"},"PeriodicalIF":0.4000,"publicationDate":"2024-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2212555824001200","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}

引用次数: 0

Abstract

Oral squamous cell carcinoma (OSCC) is a differential diagnosis of subgemmal neurogenous plaque (SNP), however cases of both adjacent lesions is extremely rare. Usually, SNP is associated with severe and persistent pain, a symptom rarely seen in early-stage OSCC. Here, we present a 47-year-old female patient complaining of severe pain upon touch, eating, or drinking in the posterior third of the lateral border of the tongue for one year, which was diagnosed as SNP. However, the symptoms did not decrease, and changed location to the middle third of the lateral border of the tongue, together with the appearance of a new lesion, which was diagnosed as OSCC. While the simultaneous occurrence of OSCC and SNP in the oral cavity is uncommon, pain has been reported as the initial symptom of malignancy in such cases.

查看原文本刊更多论文

巨网膜下神经源性斑块与口腔鳞状细胞癌：关联还是巧合？

口腔鳞状细胞癌（OSCC）是一种鉴别诊断的鞘下神经性斑块（SNP），但两种相邻病变的病例极为罕见。通常，SNP与严重和持续的疼痛有关，这种症状在早期OSCC中很少见到。在此，我们报告一位47岁的女性患者，主诉在舌头外侧边界后三分之一处触摸、进食或饮用时剧烈疼痛一年，诊断为SNP。然而，症状并未减轻，并改变位置至舌侧缘中三分之一，同时出现新的病变，诊断为OSCC。虽然口腔内OSCC和SNP同时发生的情况并不常见，但据报道，在这种情况下，疼痛是恶性肿瘤的初始症状。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊