Giovanna Lopes Carvalho , Juliana Mota Siqueira , Daniele Heguedusch , David Eduardo Zuluaga Liberato , Andressa Teruya Ramos , Emília Maria Gomes Aguiar , Fabio Daumas Nunes
{"title":"巨网膜下神经源性斑块与口腔鳞状细胞癌:关联还是巧合?","authors":"Giovanna Lopes Carvalho , Juliana Mota Siqueira , Daniele Heguedusch , David Eduardo Zuluaga Liberato , Andressa Teruya Ramos , Emília Maria Gomes Aguiar , Fabio Daumas Nunes","doi":"10.1016/j.ajoms.2024.07.005","DOIUrl":null,"url":null,"abstract":"<div><div>Oral squamous cell carcinoma (OSCC) is a differential diagnosis of subgemmal neurogenous plaque (SNP), however cases of both adjacent lesions is extremely rare. Usually, SNP is associated with severe and persistent pain, a symptom rarely seen in early-stage OSCC. Here, we present a 47-year-old female patient complaining of severe pain upon touch, eating, or drinking in the posterior third of the lateral border of the tongue for one year, which was diagnosed as SNP. However, the symptoms did not decrease, and changed location to the middle third of the lateral border of the tongue, together with the appearance of a new lesion, which was diagnosed as OSCC. While the simultaneous occurrence of OSCC and SNP in the oral cavity is uncommon, pain has been reported as the initial symptom of malignancy in such cases.</div></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":"37 2","pages":"Pages 376-379"},"PeriodicalIF":0.4000,"publicationDate":"2024-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Subgemmal neurogenous plaque and oral squamous cell carcinoma: Association or coincidence?\",\"authors\":\"Giovanna Lopes Carvalho , Juliana Mota Siqueira , Daniele Heguedusch , David Eduardo Zuluaga Liberato , Andressa Teruya Ramos , Emília Maria Gomes Aguiar , Fabio Daumas Nunes\",\"doi\":\"10.1016/j.ajoms.2024.07.005\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Oral squamous cell carcinoma (OSCC) is a differential diagnosis of subgemmal neurogenous plaque (SNP), however cases of both adjacent lesions is extremely rare. Usually, SNP is associated with severe and persistent pain, a symptom rarely seen in early-stage OSCC. Here, we present a 47-year-old female patient complaining of severe pain upon touch, eating, or drinking in the posterior third of the lateral border of the tongue for one year, which was diagnosed as SNP. However, the symptoms did not decrease, and changed location to the middle third of the lateral border of the tongue, together with the appearance of a new lesion, which was diagnosed as OSCC. While the simultaneous occurrence of OSCC and SNP in the oral cavity is uncommon, pain has been reported as the initial symptom of malignancy in such cases.</div></div>\",\"PeriodicalId\":45034,\"journal\":{\"name\":\"Journal of Oral and Maxillofacial Surgery Medicine and Pathology\",\"volume\":\"37 2\",\"pages\":\"Pages 376-379\"},\"PeriodicalIF\":0.4000,\"publicationDate\":\"2024-07-06\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Oral and Maxillofacial Surgery Medicine and Pathology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2212555824001200\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"DENTISTRY, ORAL SURGERY & MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2212555824001200","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}
Subgemmal neurogenous plaque and oral squamous cell carcinoma: Association or coincidence?
Oral squamous cell carcinoma (OSCC) is a differential diagnosis of subgemmal neurogenous plaque (SNP), however cases of both adjacent lesions is extremely rare. Usually, SNP is associated with severe and persistent pain, a symptom rarely seen in early-stage OSCC. Here, we present a 47-year-old female patient complaining of severe pain upon touch, eating, or drinking in the posterior third of the lateral border of the tongue for one year, which was diagnosed as SNP. However, the symptoms did not decrease, and changed location to the middle third of the lateral border of the tongue, together with the appearance of a new lesion, which was diagnosed as OSCC. While the simultaneous occurrence of OSCC and SNP in the oral cavity is uncommon, pain has been reported as the initial symptom of malignancy in such cases.