The use of ubiquinone to improve the healing of soft and hard jaw tissues – A systematic review

IF 0.4 Q4 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of Oral and Maxillofacial Surgery Medicine and Pathology Pub Date : 2024-07-19 DOI:10.1016/j.ajoms.2024.07.008

Alini Cardoso Soares , Camila Barcellos Calderipe , Rafael dos Santos Giorgis , Luisa Quevedo Grave , Antonio Cesar Manentti Fogaça , Marcos Antonio Torriani , Ana Carolina Uchoa Vasconcelos , Lauren Frenzel Schuch

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引用次数: 0

Abstract

Objective

The aim of the present study was to survey the scientific literature for conclusive evidence about the capacity of ubiquinone to improve the healing process of soft and hard jaw tissue.

Methods

A systematic review was conducted according to the PRISMA 2020 statement. An electronic search was undertaken in six databases and in the gray literature.

Results

Eight studies were identified, four of them in vitro, three in vivo, and one clinical. All articles demonstrated that ubiquinone accelerates the repair of soft tissue, whereas one study found little effect on the remodeling of bone tissue. Despite the possibility that ubiquinone application may be beneficial, the limited knowledge about the action of this coenzyme on oral tissue repair requires further preclinical studies before the development of human clinical trials.

Conclusion

This systematic review provides valuable information about potential new medications that could help the healing of oral tissues, especially for oral and maxillofacial surgeons.

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使用泛醌改善颌骨软组织和硬组织的愈合--系统综述

本研究旨在对科学文献进行调查，以寻找有关泛醌改善颌骨软硬组织愈合过程能力的确凿证据。结果共发现 8 项研究，其中 4 项为体外研究，3 项为体内研究，1 项为临床研究。所有文章都表明泛醌能加速软组织的修复，而一项研究发现它对骨组织的重塑几乎没有影响。尽管应用泛醌可能有益，但由于对这种辅酶对口腔组织修复作用的了解有限，因此在开展人体临床试验之前需要进一步进行临床前研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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