Annals of Geriatric Medicine and Research最新文献

{"title":"Optimal Cutoff Values of Site-Specific Phase Angle for Predicting Independence in Activities of Daily Living in Post-stroke Patients.","authors":"Yoshihiro Yoshimura, Hidetaka Wakabayashi, Fumihiko Nagano, Ayaka Matsumoto, Sayuri Shimazu, Ai Shiraishi, Yoshifumi Kido, Takahiro Bise, Takenori Hamada, Kouki Yoneda","doi":"10.4235/agmr.25.0028","DOIUrl":"10.4235/agmr.25.0028","url":null,"abstract":"<p><strong>Background: </strong>Phase angle (PhA) is a potential indicator of nutritional status and functional outcomes. However, optimal regional PhA cutoff values for predicting activities of daily living (ADL) post-stroke are unclear. We aimed to determine these cutoffs and assess whether PhA adds prognostic value to established clinical models.</p><p><strong>Methods: </strong>In this retrospective cohort study, stroke patients undergoing inpatient rehabilitation had body composition and PhA measured via multi-frequency bioelectrical impedance analysis. The primary outcome was ADL independence at discharge (motor Functional Independence Measure &gt;78). Receiver operating characteristic (ROC) curves identified optimal PhA cutoffs; logistic regression assessed their predictive value, adjusting for confounders. Incremental discriminative ability was evaluated using area under the ROC curve (AUC) comparisons with DeLong's test.</p><p><strong>Results: </strong>Among 1,080 patients (median age, 75.6 years; 54.1% men), optimal PhA cutoffs were: whole-body (women 3.90°, men 4.60°), non-paretic upper limb (4.45°, 4.90°), and non-paretic lower limb (4.00°, 4.80°). Higher PhA values above these cutoffs were independently associated with ADL independence (all p&lt;0.05). Adding whole-body PhA to the baseline model improved AUC from 0.937 to 0.970 (ΔAUC=0.033; p=0.011); significant gains were observed for limb PhA.</p><p><strong>Conclusions: </strong>Optimal site-specific PhA cutoffs predict ADL independence at discharge in post-stroke patients. PhA provides significant incremental prognostic value beyond established clinical models, supporting its use in tailoring rehabilitation strategies.</p>","PeriodicalId":44729,"journal":{"name":"Annals of Geriatric Medicine and Research","volume":"29 3","pages":"403-413"},"PeriodicalIF":3.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12489603/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145193470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between Frailty, Locomotive Syndrome, and Participation Frequency in a Long-Term Care Prevention Program among Community-Dwelling Japanese Older Adults: A Sex-Specific Analysis.","authors":"Tamaki Hirose, Yohei Sawaya, Masahiro Ishizaka, Naori Hashimoto, Tomohiko Urano","doi":"10.4235/agmr.25.0047","DOIUrl":"10.4235/agmr.25.0047","url":null,"abstract":"<p><strong>Background: </strong>To examine the association between participation frequency in the long-term care prevention program and frailty and locomotive syndrome (LS), stratified by sex.</p><p><strong>Methods: </strong>A total of 486 older adults residing in City A, Tochigi Prefecture, were included in this study. The participants were categorized into three groups based on the frequency of participation in the long-term care prevention program: low participation, medium participation, and high participation groups. Frailty was assessed using the Questionnaire for Medical Checkup of Old-Old (QMCOO), and LS was assessed using the 5-question Geriatric Locomotive Function Scale (GLFS-5). Frailty and LS were compared separately for men and women in three groups. Additionally, a binomial logistic regression analysis was conducted to examine the association between non-frailty and participation frequency in men.</p><p><strong>Results: </strong>A total of 141 participants (29.0%) were classified as having frailty, and 160 (32.9%) met the criteria for LS. Intergroup comparisons showed significant differences in frailty prevalence, QMCOO Q1, and Q5, and LS total GLFS-5 score and GLFS-5 Q3, Q4, and Q5 in men. In contrast, intergroup item comparisons showed no significant differences in women. High participation was associated with non-frailty in men across all models in the binomial logistic regression analysis.</p><p><strong>Conclusions: </strong>For men, a higher frequency of participation in the long-term care prevention program was suggested to be associated not only with frailty but also with components of LS. These findings highlight the importance of promoting social participation among men, maintaining social participation among women, and adopting sex-specific approaches within community settings.</p>","PeriodicalId":44729,"journal":{"name":"Annals of Geriatric Medicine and Research","volume":"29 3","pages":"384-392"},"PeriodicalIF":3.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12489594/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145193465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Computational Thinking as a Novel Framework for Enhancing Cognitive Organization in Older Adults with Cognitive Frailty.","authors":"Daisuke Akiba, Mari Hirano","doi":"10.4235/agmr.25.0096","DOIUrl":"10.4235/agmr.25.0096","url":null,"abstract":"","PeriodicalId":44729,"journal":{"name":"Annals of Geriatric Medicine and Research","volume":" ","pages":"418-420"},"PeriodicalIF":3.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12489599/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144683341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Position statement: Evidence-Based Exercise Guidelines for Sarcopenia in Older Adults: Insights from the Korean Working Group on Sarcopenia.","authors":"Seongryu Bae, Sunga Kong, Chul-Hyun Kim, Ji-Seok Kim, Jin-Ho Koh, Sang Ki Lee, Seok-Ki Min, Seungyong Lee, Jun-Il Yoo, Deog-Yoon Kim, Hyuntae Park, Changsun Kim","doi":"10.4235/agmr.25.0052","DOIUrl":"10.4235/agmr.25.0052","url":null,"abstract":"<p><strong>Background: </strong>Sarcopenia is a geriatric muscle disease characterized by the loss of muscle mass, strength, and physical function. To better reflect the unique characteristics of sarcopenia in Korean older adults, the Korean Working Group on Sarcopenia (KWGS) developed a diagnostic algorithm, including a new category of \"functional sarcopenia.\" This study aimed to establish evidence-based exercise guidelines tailored to the KWGS framework.</p><p><strong>Methods: </strong>A multidisciplinary expert committee conducted a systematic review of randomized controlled trials (RCTs) published between 2000 and 2024 to assess exercise interventions according exercise interventions by FITT (frequency, intensity, time, type) principles. Five key questions were developed, focusing on optimizing exercise modalities to improve muscle mass, strength, and physical performance in older adults with or without sarcopenia.</p><p><strong>Results: </strong>A total of 42 RCTs met the inclusion criteria. Resistance training was most effective for improving muscle mass and strength, while combined resistance and aerobic exercise is most effective for enhancing physical function. The guideline recommends individualized exercise prescriptions based on sarcopenia subtypes and specific functional deficits, supported by evidence grades and levels.</p><p><strong>Conclusion: </strong>This is the first Korean evidence-based exercise guideline developed within the KWGS algorithm, offering clinical and community practitioners specific, actionable strategies for preventing and managing sarcopenia. It supports tailored interventions using FITT principles aligned with individual goals and sarcopenia classification.</p>","PeriodicalId":44729,"journal":{"name":"Annals of Geriatric Medicine and Research","volume":"29 3","pages":"278-294"},"PeriodicalIF":3.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12489597/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145193437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postural Control Measures in Randomized Controlled Trials for Older Adults Balance: A Systematic Scoping Review.","authors":"Romain Pichon, Jeremy Enez, Kathryn M Sibley, Benjamin Landre, Karim Jamal","doi":"10.4235/agmr.25.0019","DOIUrl":"10.4235/agmr.25.0019","url":null,"abstract":"<p><p>The aim of this work was to identify and characterize the measures employed for assessing postural control in randomized controlled trials (RCTs) of balance interventions in older adults with the reference to the Systems Framework for Postural Control. A scoping review was conducted, and RCTs of balance interventions in older adults published from 2013 to March 2023 were considered for inclusion. Two hundred and seventy-one studies were included with a total of 49 different measures used; the Timed Up and Go test being the most commonly employed. The median number of components of postural control assessed per study was five. The most frequently assessed components were motor systems and static stability, while reactive postural control, cognitive influences and verticality were the least frequently assessed. Postural control in RCTs of balance in older adults was assessed using a wide range of measures, but also from the perspective of a limited number of components.</p>","PeriodicalId":44729,"journal":{"name":"Annals of Geriatric Medicine and Research","volume":"29 3","pages":"305-313"},"PeriodicalIF":3.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12489596/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145193444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between Physical Activity, Depression Severity and Parkinson&apos;s Symptoms in Older Adults with Parkinson&apos;s disease: A Cross-Sectional Study.","authors":"Younguk Kim, Dong Hyun Kim","doi":"10.4235/agmr.25.0034","DOIUrl":"10.4235/agmr.25.0034","url":null,"abstract":"<p><strong>Background: </strong>Depression significantly impacts Parkinson&apos;s disease (PD) motor function, non-motor symptoms, and quality of life. While physical activity (PA) is associated with improved PD symptoms, the relationship between depression severity, PA levels, and PD symptoms remains underexplored. This study examines the associations between depression severity, PA, and PD motor and non-motor symptoms using a large dataset from the Fox Insight study.</p><p><strong>Methods: </strong>This cross-sectional study analyzed data from 3,445 individuals with PD completed the Geriatric Depression Scale-Short Form (GDS-S), the Physical Activity Scale for the Elderly (PASE), the Unified Parkinson&apos;s Disease Rating Scale Part 2 (UPDRS-2), and the Non-Motor Symptoms Questionnaire (NMSQ). Participants were categorized into four groups based on GDS-S scores: normal (0-4), mild (5-8), moderate (9-11), and severe (≥12). Kruskal-Wallis tests, Pearson correlations, and multiple linear regression analyses were conducted to assess associations between depression severity, PA, and PD symptoms.</p><p><strong>Results: </strong>Higher depression severity was associated with worse motor (UPDRS-2; χ²=756.72, p&lt;0.001) and non-motor (NMSQ; χ²=1072.13, p&lt;0.001) symptoms and lower PA levels (PASE; χ²=396.24, p&lt;0.001). Regression analysis showed that NMSQ (β=0.449, p&lt;0.001), UPDRS-2 (β=0.212, p&lt;0.001), and PASE (β=-0.171, p&lt;0.001) significantly predicted depression severity.</p><p><strong>Conclusion: </strong>Depression severity in PD is strongly linked to increased PD symptom. These findings highlight the importance of integrating PA interventions and mental health strategies into PD management to improve overall well-being.</p>","PeriodicalId":44729,"journal":{"name":"Annals of Geriatric Medicine and Research","volume":" ","pages":"360-367"},"PeriodicalIF":3.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12489604/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144081234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health-Promoting Behaviors and their Associations with Frailty, Depression, and Social Support in Thai Community-Dwelling Older Adults: A Cross-Sectional Analysis.","authors":"Bovornpot Choompunuch, Dussadee Lebkhao, Wipanee Suk-Erb, Hisako Matsuo","doi":"10.4235/agmr.25.0080","DOIUrl":"10.4235/agmr.25.0080","url":null,"abstract":"<p><strong>Background: </strong>As the global population ages, including Thailand, health-promoting behaviors (HPBs) have emerged as critical challenges affecting the well-being of community-dwelling older adults. This situation calls for a deeper understanding of the modifiable protective factors involved. The current study aimed to examine the associations between frailty, depression, social support, health literacy (HL), and HPBs among community-dwelling older adults in Thailand.</p><p><strong>Methods: </strong>A cross-sectional study with a convenience sample of 250 older adults was employed. We collected using validated questionnaires-including Tilburg Frailty Indicator, Thai Geriatric Depression Scale, Social Support Scale, Health Literacy Scale, and Health Promoting Behaviors Scale. We analyzed using descriptive statistics and stepwise multiple linear regression.</p><p><strong>Results: </strong>This study involved a total of 250 community-dwelling older adults, with a mean age of 70.41 years. The participants had a mean frailty score of 6.78±1.95, indicating that most were classified as frail (score ≥5) based on the Tilburg Frailty Indicator. They also reported no significant depressive symptoms (3.80±2.62), moderate levels of social support (36.70±4.20), poor health literacy (33.15±2.71), and moderate health-promoting behaviors (101.19±7.67). Health literacy, social support, frailty, depression, and comorbidity conditions were significant predictors of health-promoting behaviors, collectively explaining 80.5% of the variance.</p><p><strong>Conclusion: </strong>These findings emphasize that improved HL, greater social support, reduced frailty, and lower depression scores were associated with healthier behaviors in older adults. Multidisciplinary healthcare teams should consider these factors when designing their intervention strategies to gain a more comprehensive understanding and improve health outcomes.</p>","PeriodicalId":44729,"journal":{"name":"Annals of Geriatric Medicine and Research","volume":"29 3","pages":"393-402"},"PeriodicalIF":3.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12489605/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145193435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Community-Acquired Pneumonia with Pseudomonas aeruginosa in a Geriatric Patient with Rheumatoid Arthritis under Baricitinib Treatment.","authors":"Eva Grundmann, Ghazala Gohar, Simon Meier, Bertram Feil, Michael Gagesch","doi":"10.4235/agmr.24.0191","DOIUrl":"10.4235/agmr.24.0191","url":null,"abstract":"<p><p>Community-acquired pneumonia (CAP) in older patients presents unique diagnostic challenges. Unlike typical presentations with fever and cough, older adults may experience atypical symptoms like falls, confusion, or chronic disease deterioration. Immunomodulatory treatments for autoimmune diseases further complicate infection risks. This is the first case of a severe Pseudomonas aeruginosa pneumonia in an 86-year-old rheumatoid arthritis patient on baricitinib and prednisone. Initially admitted after a fall, she showed no respiratory symptoms but had a chest x-ray revealing extensive infiltrative consolidation. Sputum analysis confirmed the pneumonia, which was successfully treated with antibiotics. Following the resolution of the infection, the immunomodulatory therapy could be safely reintroduced. The case underscores the critical need for comprehensive diagnostic evaluation in older adults on immunomodulatory therapy, emphasizing that subtle, non-respiratory symptoms can mask serious infections and require heightened clinical suspicion.</p>","PeriodicalId":44729,"journal":{"name":"Annals of Geriatric Medicine and Research","volume":" ","pages":"414-417"},"PeriodicalIF":3.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12489608/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144129205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrated Community Care in Korea: Implementation and Challenges.","authors":"Soong-Nang Jang","doi":"10.4235/agmr.25.0150","DOIUrl":"10.4235/agmr.25.0150","url":null,"abstract":"","PeriodicalId":44729,"journal":{"name":"Annals of Geriatric Medicine and Research","volume":"29 3","pages":"275-277"},"PeriodicalIF":3.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12489598/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145193472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Heart Failure in Patients with Sarcopenia: Systematic Review and Meta-Analysis.","authors":"Pedro Ivo Carmo Campos, Juliano Bergamaschine Mata Diz, Amanda Aparecida Oliveira Leopoldino, Marcus Vinicius Bolivar Malachias","doi":"10.4235/agmr.24.0186","DOIUrl":"10.4235/agmr.24.0186","url":null,"abstract":"<p><strong>Background: </strong>The prevalence of sarcopenia and heart failure (HF) is estimated to be between 8%-34% and 3%-11.8%, respectively. The prevalence of HF in patients with sarcopenia and the prognosis of this association remain unclear.</p><p><strong>Methods: </strong> A systematic review was conducted across MEDLINE/PubMed, Embase, CENTRAL, SciELO, and CINAHL databases, with manual searches in Google Scholar and grey literature. Meta-analysis was performed on the gathered results to assess the prevalence of HF in patients with sarcopenia, estimate phenotypes related to left ventricular ejection fraction (LVEF), and evaluate the associated mortality risk.</p><p><strong>Results: </strong>Out of 7,080 studies, 16 were selected. In patients with sarcopenia, HF prevalence was 32% (95% CI 0.07-0.61, p&lt;0.001, I²=100%). Patients with both conditions showed 45.9% (95% confidence interval [CI], 0.34-0.58; p&lt;0.001, I²=90.69%) with reduced LVEF, 10.3% (95% CI, 0.00-0.29; p&lt;0.001, I²=99%) with mildly reduced LVEF, and 29.1% (95% CI, 0.14-0.45; p&lt;0.001, I²=99%) having preserved LVEF.</p><p><strong>Conclusion: </strong>HF is highly prevalent in patients with sarcopenia and increases mortality risk.</p>","PeriodicalId":44729,"journal":{"name":"Annals of Geriatric Medicine and Research","volume":" ","pages":"295-304"},"PeriodicalIF":3.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12489607/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144020611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}