{"title":"Relationships between in-person and digital social interactions with family and friends and loneliness among older adults in Japan: A cross-sectional analysis of the 2024 JACSIS.","authors":"Yu Koizumi, Takeshi Miura, Kazumi Kubota, Miya Aishima, Yukiko Matsumura, Yuka Kanoya, Takahiro Tabuchi","doi":"10.4235/agmr.25.0215","DOIUrl":"https://doi.org/10.4235/agmr.25.0215","url":null,"abstract":"<p><strong>Background: </strong>This study examined how the frequency of in-person, telephone, text-based communication, and video interactions with non-cohabiting family and friends relates to loneliness among older adults in Japan.</p><p><strong>Methods: </strong>We analyzed data from 6,786 adults aged ≥65 in the 2024 JACSIS study. Interaction frequency with non-cohabiting family and friends was categorized into none (reference), monthly, and weekly or more. Loneliness was measured using the 3-item UCLA Loneliness Scale and dichotomized at ≥4, indicating loneliness; a ≥7 cut-off was used in sensitivity analyses. Logistic regression models adjusted for sociodemographic, lifestyle, and health-related factors.</p><p><strong>Results: </strong>For family, significant associations with lower loneliness were observed only at weekly frequencies (in-person: adjusted odds ratio [aOR] 0.764, 95% confidence interval [CI] 0.664-0.879; text: aOR 0.747, 95% CI 0.659-0.846; telephone: aOR 0.624, 95% CI 0.543-0.718), whereas for friends, significant associations were observed at monthly frequencies (in-person: aOR 0.621, 95% CI 0.549-0.701; text: aOR 0.881, 95% CI 0.778-0.997; telephone: aOR 0.734, 95% CI 0.659-0.819). Video calls were associated with lower odds of severe loneliness (score ≥7) in sensitivity analyses (weekly calls with family: aOR 0.736, 95% CI 0.547-0.991; monthly calls with friends: aOR 0.656, 95% CI 0.470-0.917).</p><p><strong>Conclusions: </strong>Interactions with friends show associations with lower levels of loneliness at lower frequencies than family contact. While text and phone calls are broadly associated with reduced loneliness, video calls demonstrate a notable link specifically with a lower prevalence of severe loneliness, underscoring the potential for tailored communication strategies.</p>","PeriodicalId":44729,"journal":{"name":"Annals of Geriatric Medicine and Research","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147784944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Validity and reliability of smartphone-based cognitive assessment in older adults.","authors":"Mokyung Jung, Fumiharu Togo","doi":"10.4235/agmr.25.0175","DOIUrl":"https://doi.org/10.4235/agmr.25.0175","url":null,"abstract":"<p><strong>Background: </strong>This study examined the validity and reliability of two smartphone-based tasks, the Symbol Search Task (SST-SP) and the Dot Memory Task (DMT-SP), in cognitively healthy older adults.</p><p><strong>Methods: </strong>Sixty participants (32 older and 28 younger adults) completed two sessions approximately one week apart. In the first session, participants performed standardized cognitive tests (Symbol Digit Substitution Test and Visual Digit Span Test) on a personal computer (PC), PC-based Symbol Search Task (SST-PC), and Dot Memory Task (DMT-PC), followed by the SST-SP and DMT-SP. The second session included only SST-SP and DMT-SP.</p><p><strong>Results: </strong>In older adults, the correlation between the SST-SP and SST-PC was strong (r = 0.83). In addition, the SST-SP showed a moderate correlation with the Symbol Digit Substitution Test (r = 0.50). A strong correlation was observed between DMT-SP and DMT-PC (r = 0.86). The DMT-SP also showed a moderate correlation with the Visual Digit Span Test (r = -0.47). The SST-SP demonstrated good test-retest reliability and high split-half reliability, whereas the DMT-SP showed moderate test-retest reliability and acceptable-to-good split-half reliability. Older adults scored lower than younger adults on both the SST-SP and DMT-SP.</p><p><strong>Conclusions: </strong>The SST-SP and DMT-SP are valid and reliable tools for assessing processing speed and working memory, respectively, in cognitively healthy older adults. These tools may provide new strategies for assessing the cognitive performance and/or ability in older adults in both research and clinical settings.</p>","PeriodicalId":44729,"journal":{"name":"Annals of Geriatric Medicine and Research","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147724126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dao Thi Ngoc Nguyen, Vu Ton Ngoc Phan, Huy Mach Thai Tran, Hung Quoc Ha, Hieu Minh Dang, Phat Thanh Tran, Sang Thanh Nguyen, Phuc Tan Nguyen Le
{"title":"Age, Comorbidities, and Outcomes Following Hip Arthroplasty: A Retrospective Cohort Study from Vietnam.","authors":"Dao Thi Ngoc Nguyen, Vu Ton Ngoc Phan, Huy Mach Thai Tran, Hung Quoc Ha, Hieu Minh Dang, Phat Thanh Tran, Sang Thanh Nguyen, Phuc Tan Nguyen Le","doi":"10.4235/agmr.25.0172","DOIUrl":"https://doi.org/10.4235/agmr.25.0172","url":null,"abstract":"<p><strong>Background: </strong>While advanced age is a known risk factor for postoperative complications following hip arthroplasty, its role as an independent predictor versus a surrogate for comorbidity remains unclear, particularly in developing countries. This study aimed to investigate the independent impact of age on postoperative outcomes and explore the mediating role of key comorbidities in a resource-limited setting.</p><p><strong>Methods: </strong>We retrospectively reviewed 769 adult patients undergoing hip arthroplasty at a Vietnamese tertiary hospital (2021-2024), categorized into three groups: younger adults (18-64 years), older adults (65-79 years), and oldest old (≥80 years). The primary outcome was a composite of major postoperative complications. Multivariable logistic regression and structural equation modeling were used to identify independent predictors and assess mediation effects.</p><p><strong>Results: </strong>Among 769 patients, 363 were younger adults (47.2%) , 241 older adults (31.3%), and 165 oldest old (21.5%). Complication rates increased significantly with age (18.7%, 36.9%, and 60.0%, respectively; p < 0.001). However, multivariable adjustment showed that age was not an independent predictor. Instead, heart failure (aOR: 5.10, 95% CI: 1.97-13.20) and preoperative anemia (aOR: 1.77, 95% CI: 1.21-2.59) were identified as independent risk factors. Mediation analysis revealed that the effect of age on complications was significantly mediated through preoperative anemia.</p><p><strong>Conclusions: </strong>Increased postoperative risk in older adults is driven by comorbidity burden rather than chronological age. Preoperative anemia and heart failure are critical, independent predictors, with anemia acting as a key mediator for the effects of age. Individualized correction of modifiable comorbidities may be more beneficial than using age alone to assess surgical risk.</p>","PeriodicalId":44729,"journal":{"name":"Annals of Geriatric Medicine and Research","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147724112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hyerim Choi, Eung-Joon Lee, Mee Jee Kim, Ga Hyun Kim, Shinwoong Kim, Namhee Kim, Jeong Yeon Seok, A Jeong Kim, Yun Hee Jo, Yoonsook Cho, Keun-Hwa Jung
{"title":"High-intensity statin therapy and functional independence after acute ischemic stroke in adults aged 75 years and older: a retrospective, single-center cohort study.","authors":"Hyerim Choi, Eung-Joon Lee, Mee Jee Kim, Ga Hyun Kim, Shinwoong Kim, Namhee Kim, Jeong Yeon Seok, A Jeong Kim, Yun Hee Jo, Yoonsook Cho, Keun-Hwa Jung","doi":"10.4235/agmr.25.0202","DOIUrl":"https://doi.org/10.4235/agmr.25.0202","url":null,"abstract":"<p><strong>Background: </strong>Older patients aged ≥75 years are underrepresented in major statin trials, leaving the optimal statin intensity after acute ischemic stroke (AIS) undefined. We aimed to compare functional outcomes and short-term safety between high-intensity statin therapy (HIST) and moderate-intensity statin therapy (MIST) in patients aged ≥75 years with AIS or transient ischemic attack.</p><p><strong>Methods: </strong>Using a prospective stroke registry at a single tertiary center (2019-2022), we retrospectively analyzed 337 patients aged ≥75 years with AIS or transient ischemic attack who maintained statin therapy for 3 months (HIST n=117; MIST n=220). The primary outcome was a favorable 3-month functional outcome (modified Rankin Scale score 0-2). Secondary outcomes included stroke recurrence, adverse effects, and statin discontinuation. Multivariable logistic regression with pre-specified sensitivity analyses was performed.</p><p><strong>Results: </strong>Favorable outcomes at 3 months were more frequent with HIST (70.9% vs. 55.9%; p=0.010). After multivariable adjustment, HIST was independently associated with a favorable outcome (adjusted odds ratio [aOR] 2.03, 95% confidence interval [CI] 1.17-3.53), consistent across sensitivity analyses: per-protocol (aOR 3.48, 95% CI 1.97-6.17) and atrial fibrillation-adjusted (aOR 2.21, 95% CI 1.26-3.89). No significant differences were observed in statin discontinuation, stroke recurrence, or adverse effects.</p><p><strong>Conclusions: </strong>In older patients with AIS, HIST was independently associated with better functional outcomes without evidence of increased harm, broadly consistent with current guideline recommendations for HIST when tolerated. Prospective studies are needed to confirm a causal relationship.</p>","PeriodicalId":44729,"journal":{"name":"Annals of Geriatric Medicine and Research","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147677389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Associations between Fear of Crime and Symptom Burden among non-victimized Older Adults: Findings from the Swedish Population-Based Study \"Good Aging in Skåne\".","authors":"Emil Larsson, Sölve Elmståhl, Henrik Ekström","doi":"10.4235/agmr.25.0186","DOIUrl":"https://doi.org/10.4235/agmr.25.0186","url":null,"abstract":"<p><strong>Background: </strong>Although older adults are statistically less likely to be exposed to crime, they tend to worry more about it compared to younger adults. Fear of crime (FOC) has been associated with lower life satisfaction, dependence in activities of daily living, poorer mental health, and reduced self-reported physical health. Few studies have compared different age groups among older adults or examined its relationship with various symptoms of common diseases. This study aimed to improve understanding of the association between behavioral FOC and symptom burden.</p><p><strong>Methods: </strong>This cross-sectional study comprised 5,832 participants aged 60-96 years from the Swedish \"Good Aging in Skåne\" general population study. Data were collected through questionnaires, medical examinations, and patient journal reviews. Linear and logistic regression models, adjusted for age, gender, sociodemographic and health factors, were used to examine associations between FOC, the number of perceived symptoms, and prevalence of different symptom domains.</p><p><strong>Results: </strong>Overall, 34.7% of participants reported refraining from going out in the evening at least occasionally due to fear of crime or threats during the past year, with higher prevalence among women and individuals aged 70 years and older. Statistically significant associations were found between FOC and both the number of reported symptoms and several symptom domains.</p><p><strong>Conclusion: </strong>Fear of crime is common among older adults, particularly in women, and is associated with an increased total number of symptoms and certain symptom domains. FOC should be recognized as a crucial factor influencing older adults' lives, with extensive health consequences.</p>","PeriodicalId":44729,"journal":{"name":"Annals of Geriatric Medicine and Research","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147582627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jeffrey Cayaban Pagaduan, Melvin Barrientos Marzan, Xiaoling Wang, Benjamin Billot
{"title":"A Case Series on Longitudinal Hypothalamic Morphology in Mild Cognitive Impairment.","authors":"Jeffrey Cayaban Pagaduan, Melvin Barrientos Marzan, Xiaoling Wang, Benjamin Billot","doi":"10.4235/agmr.25.0122","DOIUrl":"https://doi.org/10.4235/agmr.25.0122","url":null,"abstract":"<p><p>We examined the longitudinal hypothalamic morphology in the progression of mild cognitive impairment (MCI). We used multivariable linear modelling to differentiate the structural volumetric change in the hypothalamic nuclei in nine females who developed MCI after 5 years and 61 healthy controls. We found significantly decreased left anterior-inferior (p < 0.01), left anterior-superior (p < 0.05), and left posterior (p < 0.01) hypothalamic regions among females with MCI compared to healthy controls. There was also a significant asymmetry at the anterior-superior hypothalamus (p < 0.05) in MCI females than in healthy controls. Thus, the degradation of the specific left hypothalamic subregions and leftward lateralization over time highlight the impact of early-stage MCI on the morphology of hypothalamus.</p>","PeriodicalId":44729,"journal":{"name":"Annals of Geriatric Medicine and Research","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147582662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association between participation in a municipality-led walking program and readiness for lifestyle improvement among community-dwelling older adults: a retrospective comparative study using linked administrative data.","authors":"Takeshi Miura, Makoto Kuroki, Sayuri Shimizu","doi":"10.4235/agmr.25.0200","DOIUrl":"https://doi.org/10.4235/agmr.25.0200","url":null,"abstract":"<p><strong>Background: </strong>Promoting physical activity among older adults is essential for extending healthy life expectancy. Municipality-led walking programs have been introduced in Japan; however, evidence of their effectiveness in promoting readiness for lifestyle improvement among older adults remains limited. We examined the association between participation in a municipality-led walking promotion program and readiness for lifestyle improvement among community-dwelling older adults.</p><p><strong>Methods: </strong>Data of community-dwelling adults aged ≥65 years who participated in a municipality-led walking promotion program implemented in Zushi City, Japan, in 2021, were compared with those of non-participants selected from the National Health Insurance database. Behavioral readiness was evaluated using the five-stage classification of the transtheoretical model. Pre- and post-intervention stages were assessed in both groups. Associations between participation and behavioral stage were examined using ordinal logistic regression with unadjusted, basic-adjusted, and fully adjusted models, controlling for baseline stage and habitual exercise.</p><p><strong>Results: </strong>Participants in the walking event had higher odds of being at a higher readiness stage than non-participants (unadjusted odds ratio [OR] = 2.91; basic-adjusted OR = 2.99; fully adjusted OR = 2.98). Analyses using a dichotomized transtheoretical model variable also indicated consistently higher odds of being in the action or maintenance stages among participants.</p><p><strong>Conclusion: </strong>Our findings suggest that short-term, municipality-led walking initiatives contribute to early-stage behavioral readiness for lifestyle improvement in older adults. They provide a valuable foundation for planning community-based health promotion and long-term care prevention strategies. Further studies are needed to evaluate similar programs across different settings and over more extended periods.</p>","PeriodicalId":44729,"journal":{"name":"Annals of Geriatric Medicine and Research","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147515302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Iku Nishimura, Kenji Tsunoda, Yuya Fujii, Koki Nagata, Bora Hwang, Tomohiro Okura
{"title":"Prospective associations between self-perceived voice disorders and psychological, social, and physical well-being among community-dwelling older adults.","authors":"Iku Nishimura, Kenji Tsunoda, Yuya Fujii, Koki Nagata, Bora Hwang, Tomohiro Okura","doi":"10.4235/agmr.25.0163","DOIUrl":"https://doi.org/10.4235/agmr.25.0163","url":null,"abstract":"<p><strong>Background: </strong>Self-perceived voice disorders (PVD) are common in later life and may affect psychological, social, and physical well-being. However, longitudinal evidence in community settings remains limited. This study sought to examine whether PVD predicted changes in well-being among community-dwelling older adults.</p><p><strong>Methods: </strong>Data were obtained from a community cohort in Kasama City, Japan. Older adults (n = 273; aged 76.5 years; 57.1% women) were classified based on baseline Voice Handicap Index-10 scores (0: no, 1-4: mild, and ≥5: PVD). Outcomes were assessed annually through 2025 using the Geriatric Depression Scale (GDS), Lubben Social Network Scale (LSNS), Physical Activity Scale for the Elderly (PASE), and physical performance measures (handgrip strength, single-leg balance with eyes open, sit-and-reach, and 5-m habitual walk). Linear mixed models analyzed the fixed effects of group, time, and their interaction while adjusting for selected covariates.</p><p><strong>Results: </strong>Significant group effects were observed for the GDS, total LSNS scores, and the LSNS family scale, indicating that participants with PVD had weakened psychological and social well-being and smaller family networks. Additionally, a notable group effect was observed in sit-and-reach, with PVD participants showing less flexibility than those without it in the physical performance measures.</p><p><strong>Conclusion: </strong>Among community-dwelling older adults, PVD was prospectively associated with increased depressive symptoms, diminished social networks, particularly smaller family networks, and reduced physical flexibility. These findings suggest that PVD preceding medical diagnosis may signal broader declines in psychological, social, and physical well-being, highlighting the importance of early identification and support.</p>","PeriodicalId":44729,"journal":{"name":"Annals of Geriatric Medicine and Research","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147515289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Co-existence of Possible Sarcopenia and Dysphagia is Associated with Poor Functional Outcomes in Patients with Acute Stroke: A 1-Year Follow-up Study.","authors":"Yoichi Sato, Takafumi Abe, Yosuke Kimura, Shu Tanaka, Kazuki Okuda, Ayaki Shirahata, Kenta Yamamoto, Kazushige Ide, Masafumi Nozoe","doi":"10.4235/agmr.26.0002","DOIUrl":"https://doi.org/10.4235/agmr.26.0002","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to clarify the association between the co-existence of possible sarcopenia (PS) and dysphagia in patients with acute stroke and the functional outcomes 12 months after stroke.</p><p><strong>Methods: </strong>This multicenter retrospective cohort study was conducted on patients with stroke admitted to two acute care hospitals in Japan between November 2020 and October 2023. PS was defined based on grip strength (men: <28 kg, women: <18 kg) and calf circumference (men: <34 cm, women: <33 cm) on admission. Dysphagia was defined as a Functional Oral Intake Scale score of less than 4. The outcome was defined as a composite of either poor functional outcome (modified Rankin Scale [mRS] score of 3-6) or failure to recover to the premorbid mRS at 12 months after stroke onset. Modified Poisson regression analysis was used to examine the association between the co-existence of PS and dysphagia and poor functional outcomes.</p><p><strong>Results: </strong>This study included 604 patients (median age: 76 years; 367 men). Compared with the non-PS and non-dysphagia group, the PS and dysphagia group had a higher proportion of poor functional outcomes. Subsequently, modified Poisson regression analysis was performed. The interaction between PS and dysphagia was significantly associated with poor functional outcomes (risk ratio = 4.348, 95% confidence interval: 2.683-7.046).</p><p><strong>Conclusions: </strong>In patients with acute stroke, the co-existence of PS and dysphagia was associated with poor functional outcomes 12 months after stroke. Future multicenter prospective interventional studies are required to clarify the effectiveness of multifaceted intervention programs in high-risk patients.</p>","PeriodicalId":44729,"journal":{"name":"Annals of Geriatric Medicine and Research","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147475775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association of Cachexia with Activities of Daily Living and Discharge Destinations among Inpatients with Dysphagia undergoing Convalescent Rehabilitation: A Multicenter Cohort Study.","authors":"Shintaro Togashi, Tomoyuki Murakami, Hidetaka Wakabayashi, Akio Shimizu, Shinta Nishioka, Ryo Momosaki","doi":"10.4235/agmr.25.0048","DOIUrl":"10.4235/agmr.25.0048","url":null,"abstract":"<p><strong>Background: </strong>Although a recent study reported an association between cachexia, as defined by the Asian Working Group for Cachexia (AWGC), and lower functional recovery at discharge among post-stroke patients capable of oral intake during the convalescent rehabilitation phase, its impact on functional recovery in patients with dysphagia remains unclear. This study aimed to evaluate the association between cachexia, according to AWGC criteria, and both functional status and discharge destinations among inpatients with dysphagia.</p><p><strong>Methods: </strong>This prospective cohort study enrolled 198 inpatients with dysphagia from eight convalescent rehabilitation hospitals. Cachexia was defined using the AWGC criteria at baseline. The primary outcome was the total Functional Independence Measure (FIM) at discharge, while the secondary outcomes were the Food Intake LEVEL Scale (FILS) score and discharge destinations. We applied generalized linear models to evaluate the association between cachexia and total FIM score at discharge, adjusting for age, sex, baseline FILS score, comorbidities, and use of enteral nutrition.</p><p><strong>Results: </strong>Of 198 patients, the median age was 83.0 years (interquartile range, 77.0-88.0); 111 (56.1%) were women, and 33 (16.7%) had cachexia. After adjusting for covariates, cachexia was not significantly associated with total FIM score at discharge (β=0.03, 95% confidence interval [CI] -0.10 to 0.15, p=0.66), FILS (β=0.23, 95% CI -0.53 to 1.00, p=0.55), or discharge destinations including discharge to home (β=0.25, 95% CI -0.75 to 1.35, p=0.63).</p><p><strong>Conclusion: </strong>Cachexia, as defined by the AWGC, was not significantly associated with either functional status at discharge or discharge destinations among inpatients with dysphagia undergoing convalescent rehabilitation.</p>","PeriodicalId":44729,"journal":{"name":"Annals of Geriatric Medicine and Research","volume":" ","pages":"128-136"},"PeriodicalIF":3.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13058734/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145193393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}