Annals of Geriatric Medicine and Research最新文献

{"title":"Community-acquired pneumonia with Pseudomonas aeruginosa in a geriatric patient with rheumatoid arthritis under baricitinib treatment.","authors":"Eva Grundmann, Ghazala Gohar, Simon Meier, Bertram Feil, Michael Gagesch","doi":"10.4235/agmr.24.0191","DOIUrl":"https://doi.org/10.4235/agmr.24.0191","url":null,"abstract":"<p><p>Community-acquired pneumonia (CAP) in older unique diagnostic challenges. Unlike typical presentations with fever and cough, older may experience atypical symptoms like falls, confusion, or chronic disease deterioration. Immunomodulatory treatments for autoimmune diseases further complicate infection risks. This is the first case of a severe Pseudomonas aeruginosa pneumonia in an 86-year-old rheumatoid arthritis patient on baricitinib and prednisone. Initially admitted after a fall, she showed no respiratory symptoms but had a chest x-ray revealing extensive infiltrative consolidation. Sputum analysis confirmed the pneumonia, which was successfully treated with antibiotics. Following the resolution of the infection, the immunomodulatory therapy could be safely reintroduced. The case underscores the critical need for comprehensive diagnostic evaluation in older adults on immunomodulatory therapy, emphasizing that subtle, non-respiratory symptoms can mask serious infections and require heightened clinical suspicion.</p>","PeriodicalId":44729,"journal":{"name":"Annals of Geriatric Medicine and Research","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144129205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association Between Physical Activity, Depression Severity and Parkinson's Disease (PD) Symptoms in Older Adults with PD: A Cross-Sectional Study.","authors":"Younguk Kim, Dong Hyun Kim","doi":"10.4235/agmr.25.0034","DOIUrl":"https://doi.org/10.4235/agmr.25.0034","url":null,"abstract":"<p><strong>Background: </strong>Depression significantly impacts Parkinson's disease (PD) motor function, non-motor symptoms, and quality of life. While physical activity is associated with improved PD symptoms, the relationship between depression severity, physical activity (PA) levels, and PD symptoms remains underexplored. This study examines the associations between depression severity, PA, and PD motor and non-motor symptoms using a large dataset from the Fox Insight (FI) study.</p><p><strong>Methods: </strong>This cross-sectional study analyzed data from 3,445 individuals with PD completed the Geriatric Depression Scale-Short Form (GDS-S), the Physical Activity Scale for the Elderly (PASE), the Unified Parkinson's Disease Rating Scale Part 2 (UPDRS-2), and the Non-Motor Symptoms Questionnaire (NMSQ). Participants were categorized into four groups based on GDS-S scores: normal (0-4), mild (5-8), moderate (9-11), and severe (≥12). Kruskal-Wallis tests, Pearson correlations, and multiple linear regression analyses were conducted to assess associations between depression severity, PA, and PD symptoms.</p><p><strong>Results: </strong>Higher depression severity was associated with worse motor (UPDRS-2, χ² = 756.72, p < .001) and non-motor (NMSQ, χ² = 1072.13, p < .001) symptoms and lower PA levels (PASE, χ² = 396.24, p < .001). Regression analysis showed that NMSQ (β = 0.449, p < .001), UPDRS-2 (β = 0.212, p < .001), and PASE (β = -0.171, p < .001) significantly predicted depression severity.</p><p><strong>Conclusion: </strong>Depression severity in PD is strongly linked to increased PD symptom. These findings highlight the importance of integrating physical activity interventions and mental health strategies into PD management to improve overall well-being.</p>","PeriodicalId":44729,"journal":{"name":"Annals of Geriatric Medicine and Research","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144081234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Where is the Care for the Sense of Isolation of Hospitalized Elderly People?","authors":"Yeo Ju Lee","doi":"10.4235/agmr.25.0060","DOIUrl":"https://doi.org/10.4235/agmr.25.0060","url":null,"abstract":"","PeriodicalId":44729,"journal":{"name":"Annals of Geriatric Medicine and Research","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144081236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Differences in the health status of older adults in community and hospital cohorts.","authors":"Ji Yeon Lee, Kwang Joon Kim, Jong Eun Kim, Young Mi Yun, Eun Seo Sun, Chang Oh Kim","doi":"10.4235/agmr.24.0199","DOIUrl":"https://doi.org/10.4235/agmr.24.0199","url":null,"abstract":"<p><strong>Background: </strong>Older adults frequently utilize healthcare services across diverse medical settings to maintain continuity of care. However, data from the hospital records of older adults is often not linked to their health status in community settings, preventing a full understanding of their healthcare needs.</p><p><strong>Methods: </strong>This study aimed to compare the multidimensional health status (i.e., self-rated health, depression, physical function/activity, mobility, nutrition, lifestyle factors, blood laboratory, and diseases) of older adults between community and hospital cohorts. The goal was to identify the potential health problems of older adults and establish a preventive care system. Secondary analysis was conducted using data obtained from the Korean Urban Rural Elderly (KURE) study for the community cohort and outpatient patients from a single tertiary hospital for the hospital cohort.</p><p><strong>Results: </strong>Using age- and sex-matched propensity score matching, 550 older adults were selected equally from the two cohorts. Logistic regression was performed to predict the health status of the two groups. The health status of the community and hospital cohorts differed in several health domains. The hospital cohort group had more risk of depression, impairment in instrumental activities of daily living, and malnutrition. The hospital cohort group had lower alcohol intake and albumin, and higher glucose levels. The hospital group also had a higher prevalence of stroke and depression.</p><p><strong>Conclusion: </strong>The findings of this study highlight the need to provide multidimensional healthcare services that consider the deterioration of multiple health conditions in older adults.</p>","PeriodicalId":44729,"journal":{"name":"Annals of Geriatric Medicine and Research","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144081235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Life Expectancy of the Tokugawa Shogun Family Estimated from Edo Period Historical Records.","authors":"Hisashi Fujita, Shinya Matsukawa, Hiroomi Tsumura, Dong Hoon Shin","doi":"10.4235/agmr.25.0008","DOIUrl":"https://doi.org/10.4235/agmr.25.0008","url":null,"abstract":"<p><strong>Background: </strong>This study aims to estimate the average life expectancy (LE) of the Tokugawa Shogun family by analyzing historical documents. The data is also compared to modern Japanese life expectancy figures.</p><p><strong>Methods: </strong>The lifespan of members of the Tokugawa Shogun family is estimated based on data from Edo-period documents. We assess survival rates by age, sex, and other factors. Lunar calendar dates are converted into solar calendar dates, and birth years are counted as age 0 to ensure that the estimated LE is comparable to modern Japanese estimates, free from bias.</p><p><strong>Results: </strong>The mean life expectancy at birth (LEB) for males in the Tokugawa Shogun family is 20.93 ± 25.03 years, and for females, it is 20.53 ± 25.16 years. The pooled result for both sexes is 20.75 ± 25.00 years.</p><p><strong>Conclusions: </strong>The life expectancy of the Tokugawa Shogun family is lower than that of modern Japanese, despite their status as the supreme elite class in Edo-period Japan. This reduced life expectancy is primarily attributed to high infant mortality rates, though survival rates for individuals aged 10 and above remained relatively consistent.</p>","PeriodicalId":44729,"journal":{"name":"Annals of Geriatric Medicine and Research","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144049917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between physical function at admission and walking ability at discharge in older adults with vertebral compression fractures: an analysis using propensity score matching.","authors":"Kodai Hosaka, Hiroshi Otao, Eri Nishi, Junpei Imamura, Junko Tanaka, Hajime Shibata","doi":"10.4235/agmr.24.0180","DOIUrl":"https://doi.org/10.4235/agmr.24.0180","url":null,"abstract":"<p><strong>Background: </strong>Vertebral compression fractures (VCFs) are common among older adults, with the highest prevalence observed in Japan. These fractures cause pain, reduce quality of life, and increase the need for physical therapy. This study identified key factors at admission that predict walking ability at discharge in patients with VCFs.</p><p><strong>Methods: </strong>This retrospective cohort study included 143 patients aged ≥65 years with VCFs. VCFs are fractures in which only the anterior column of the vertebral body collapses. The primary variables assessed upon admission included the revised Hasegawa Dementia Scale (HDS-R) score, grip strength, skeletal muscle mass index (SMI), and phase angle (PhA). Propensity score matching was applied to adjust for background factors, after which a logistic regression analysis using a generalized linear model was conducted to determine whether these variables influenced walking ability at discharge.</p><p><strong>Results: </strong>Significant associations were observed between walking ability at discharge and HDS-R score at admission (p < 0.001, effect size [ES] = 0.42), grip strength (p = 0.027, ES = 0.23), SMI (p = 0.025, ES = 0.23), and PhA (p < 0.001, ES = 0.40). Logistic regression analysis indicated that HDS-R score (odds ratio [OR] = 1.19, p = 0.005) and PhA (OR = 3.21, p = 0.015) during admission significantly predicted walking ability at discharge.</p><p><strong>Conclusion: </strong>Walking ability at discharge in patients with VCFs can be predicted based on early assessments. In particular, HDS-R score and PhA at admission may serve as key indicators for prognosis in patients with VCFs.</p>","PeriodicalId":44729,"journal":{"name":"Annals of Geriatric Medicine and Research","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144055400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sarcopenic obesity defined by Japanese Working Group on Sarcopenic Obesity in post-stroke inpatients: prevalence and clinical implications.","authors":"Ayaka Matsumoto, Yoshihiro Yoshimura, Hidetaka Wakabayashi, Fumihiko Nagano, Sayuri Shimazu, Yoshifumi Kido, Ai Shiraishi, Takenori Hamada, Kouki Yoneda, Takahiro Bise, Aomi Kuzuhara","doi":"10.4235/agmr.25.0021","DOIUrl":"https://doi.org/10.4235/agmr.25.0021","url":null,"abstract":"<p><strong>Background: </strong>Sarcopenic obesity (SO) is characterized by the coexistence of sarcopenia and obesity, associated with adverse health outcomes. This study aimed to investigate the prevalence of SO as defined by the recently published Japanese Working Group on Sarcopenic Obesity (JWGSO) criteria in post-stroke patients undergoing rehabilitation and its association with activities of daily living (ADL) and length of hospital stay.</p><p><strong>Methods: </strong>This retrospective cohort study analyzed stroke patients aged 40-75 years undergoing rehabilitation. SO was diagnosed using JWGSO criteria. The primary outcome was the Functional Independence Measure (FIM) motor score at discharge, with length of hospital stay as a secondary outcome. Multiple linear regression analysis was performed to assess associations between SO and outcomes.</p><p><strong>Results: </strong>The study included 405 patients with a median age of 65 years (IQR 58-71), of whom 60.7% were male. The prevalence of JWGSO-defined SO was 5.4%. Multivariate regression analysis revealed no significant association between JWGSO-defined SO and FIM-motor at discharge (β = 0.015, p = 0.664) or length of stay (β = 0.008, p = 0.828). Sarcopenia alone demonstrated significant negative associations with both outcomes.</p><p><strong>Conclusion: </strong>The prevalence of JWGSO-defined SO in post-stroke rehabilitation patients was 5.4%, with no significant association with ADL or length of hospital stay. Sarcopenia alone showed stronger associations with outcomes, suggesting the importance of addressing muscle mass and strength in stroke rehabilitation.</p>","PeriodicalId":44729,"journal":{"name":"Annals of Geriatric Medicine and Research","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144002182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"HEART FAILURE IN PATIENTS WITH SARCOPENIA: SYSTEMATIC REVIEW AND META-ANALYSIS.","authors":"Pedro Ivo Carmo Campos, Marcus Vinicius Bolivar Malachias, Amanda Aparecida Oliveira Leopoldino, Juliano Bergamaschine Mata Diz","doi":"10.4235/agmr.24.0186","DOIUrl":"https://doi.org/10.4235/agmr.24.0186","url":null,"abstract":"<p><strong>Introduction: </strong>The prevalence of sarcopenia and heart failure (HF) is estimated to be between 8% - 34% and 3% - 11.8%, respectively. The prevalence of HF in patients with sarcopenia and the prognosis of this association remain unclear.</p><p><strong>Methods: </strong> A systematic review was conducted across MEDLINE/PubMed, Embase, CENTRAL, Scielo, and CINAHL databases, with manual searches in Google Scholar and grey literature. Meta-analysis was performed on the gathered results to assess the prevalence of HF in patients with sarcopenia, estimate phenotypes related to left ventricular ejection fraction (LVEF), and evaluate the associated mortality risk.</p><p><strong>Results: </strong>Out of 7.080 studies, 16 were selected. In patients with sarcopenia HF prevalence was 32% (95% CI 0.07-0.61, p<0.001, I²=100%). Patients with both conditions showed 45.9% (95% CI 0.34 - 0.58, p<0.001, I² 90.69%) with reduced LVEF, 10.3% (95% CI 0.00 - 0.29, p<0.001, I² 99%) with mildly reduced LVEF, and 29.1% (95% CI 0.14 - 0.45, p<0.001, I² 99%) having preserved LVEF.</p><p><strong>Conclusion: </strong>HF is highly prevalent in patients with sarcopenia and increases mortality risk.</p>","PeriodicalId":44729,"journal":{"name":"Annals of Geriatric Medicine and Research","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144020611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bridging the Gap: Addressing the Need for Home Health Care in South Korea's Aging Population.","authors":"Dae Hyun Kim, Joo Hyung Kim","doi":"10.4235/agmr.25.0023","DOIUrl":"https://doi.org/10.4235/agmr.25.0023","url":null,"abstract":"","PeriodicalId":44729,"journal":{"name":"Annals of Geriatric Medicine and Research","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143671370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Therapeutic Effects of Slow Deep Breathing on Cardiopulmonary Function, Physical Performance, Biochemical Parameters, and Stress in Older Adult Patients with Long COVID in Phayao, Thailand.","authors":"Tichanon Promsrisuk, Arunrat Srithawong, Ratchaniporn Kongsui, Napatr Sriraksa, Sitthisak Thongrong, Chiraphat Kloypan, Nattha Muangritdech, Kit Khunkitti, Thanakorn Thanawat, Petcharaporn Chachvarat","doi":"10.4235/agmr.24.0175","DOIUrl":"https://doi.org/10.4235/agmr.24.0175","url":null,"abstract":"<p><strong>Background: </strong>Long COVID poses significant challenges for older adult patients, affecting their cardiopulmonary function and overall well-being. This study aimed to investigate the effects of slow deep breathing exercises on cardiopulmonary function, physical performance, biochemical markers, oxidative stress, and stress levels in older adult patients with long COVID.</p><p><strong>Methods: </strong>Sixty older adult patients with long COVID were randomly assigned to an exercise group of 30 patients and a control group of 30 patients. The exercise group engaged in slow deep breathing exercises for 30 minutes, five times a week over a period of 8 weeks, while the control group maintained their usual activities. Cardiovascular parameters, heart rate variability (HRV), respiratory muscle strength (RMS), pulmonary function tests (PFT), physical performance, biochemical and oxidative stress markers, and stress levels were assessed at baseline, 4 weeks, and 8 weeks. Data were analyzed using one-way repeated measures ANOVA.</p><p><strong>Results: </strong>The exercise group showed significant reductions in cardiovascular parameters (systolic and diastolic blood pressure, pulse pressure, mean arterial pressure, and heart rate). Additionally, RMS, PFT, and physical performance showed significant increases. Improvements were also observed in HRV, biochemical markers (fasting blood sugar and lipid profile), oxidative stress markers (catalase, superoxide dismutase, and malondialdehyde), and stress levels. In contrast, no significant changes were found in the control group.</p><p><strong>Conclusion: </strong>Slow deep breathing exercises, as a non-pharmacological intervention, significantly improve cardiopulmonary function, physical performance, and various health markers in older adult patients with long COVID. This approach provides a valuable and accessible therapeutic option for this population.</p>","PeriodicalId":44729,"journal":{"name":"Annals of Geriatric Medicine and Research","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143568470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}