Annals of Geriatric Medicine and Research最新文献

{"title":"Impairment in activities of daily living and related factors in elderly patients with severe lumbar spinal stenosis before hospitalization.","authors":"Daigo Ishizuka, Susumu Nozaki, Hiroshi Minezaki, Tsuyoshi Ota, Yasuyoshi Asakawa","doi":"10.4235/agmr.24.0128","DOIUrl":"10.4235/agmr.24.0128","url":null,"abstract":"<p><strong>Background: </strong>Lumbar spinal stenosis (LSS) impairs activities of daily living (ADL) in older adults. Factors associated with ADL impairment in LSS have not been identified. This study aimed to ascertain the pre-admission living conditions in elderly patients with LSS and investigate the factors associated with impairment in ADL.</p><p><strong>Methods: </strong>A total of 261 community-dwelling elderly adults aged ≥65 years with LSS, scheduled for surgery were included. The Oswestry Disability Index (ODI) was used to assess ADL impairment. The Life-Space Assessment was used to assess the extent and frequency of outings. pain, numbness, continuous walking distance, and health-related quality of life as psychosomatic functions. Falls self-efficacy, and the degree of social isolation were assessed as social life status. Factors associated with ADL impairment were examined using multiple logistic regression analysis.</p><p><strong>Results: </strong>Significant differences were found in psychosomatic functioning, living space, and falls self-efficacy depending on the presence or absence of ADL impairment. The ODI sub-components showed a stronger degree of impairment in pain intensity, walking, standing, and social life. There were significant differences in the frequency of going outside the home and 　inside the neighborhood, ADL impairment was shown to affect the frequency of outings within close proximity to their lives. Numbness was associated with ADL disability (odds ratio, 1.2; 95% confidence interval: 1.1-1.4).</p><p><strong>Conclusion: </strong>Assessing the degree of numbness is important in predicting ADL impairment in older adults with LSS. Additionally, assessing the living conditions and taking an appropriate approach before admission can help prevent ADL impairment.</p>","PeriodicalId":44729,"journal":{"name":"Annals of Geriatric Medicine and Research","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142666381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Circulating BMP-7 Level is Independent of Sarcopenia in Older Asian Adults.","authors":"Ahin Choi, Ji Yeon Baek, Eunhye Ji, Il-Young Jang, Hee-Won Jung, So Jeong Park, Yunju Jo, Eunju Lee, Dongryeol Ryu, Beom-Jun Kim","doi":"10.4235/agmr.24.0153","DOIUrl":"https://doi.org/10.4235/agmr.24.0153","url":null,"abstract":"<p><strong>Background: </strong>In vitro and animal studies have demonstrated that BMP-7, renowned for its osteogenic properties, also exerts beneficial effects on muscle metabolism by enhancing myogenesis and reversing muscle atrophy. Despite being proposed as a common regulatory factor for both muscle and bone, the impact of BMP-7 on human muscle health has not been thoroughly investigated.</p><p><strong>Methods: </strong>This cross-sectional study involved 182 community-dwelling older adults who underwent a comprehensive geriatric assessment in South Korea. Sarcopenia was diagnosed using Asian-specific cutoffs, and serum BMP-7 levels were quantified via enzyme immunoassay.</p><p><strong>Results: </strong>The mean age of the participants was 72.2 ± 7.3 years, with 62.6% being female. After adjustments for confounders, serum BMP-7 levels were not significantly different between individuals with and without sarcopenia, nor were there differences based on skeletal muscle mass, strength, or physical performance levels (P = 0.423 to 0.681). Likewise, no correlations were detected between circulating BMP-7 levels and any sarcopenia assessment metrics such as skeletal muscle index, grip strength, gait speed, or chair stand completion times (P = 0.127 to 0.577). No significant associations were observed between increases in serum BMP-7 concentrations and the risk of sarcopenia or poor muscle phenotypes (P = 0.431 to 0.712). Stratifying participants into quartiles based on serum BMP-7 levels also indicated no differences in sarcopenia-related parameters (P = 0.663 to 0.996).</p><p><strong>Conclusion: </strong>Despite experimental evidence supporting BMP-7's role in muscle metabolism, this study found no significant association between serum BMP-7 levels and clinical indicators of muscle health in older adults. These findings challenge the utility of serum BMP-7 as a biomarker for sarcopenia in this demographic.</p>","PeriodicalId":44729,"journal":{"name":"Annals of Geriatric Medicine and Research","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142630265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between Muscle Mass and Muscle Strength with Bone Density in Older Adults: A Systematic Review.","authors":"Nur Riviati, Surya Darma, Muhammad Reagan, Muhammad Baharul Iman, Fara Syafira, Bima Indra","doi":"10.4235/agmr.24.0113","DOIUrl":"https://doi.org/10.4235/agmr.24.0113","url":null,"abstract":"<p><strong>Background: </strong>Understanding the relationship between muscle mass, muscle strength, and bone density in older adults is crucial for addressing age-related conditions like osteoporosis and sarcopenia. This review aims to evaluate the relationship between muscle mass and muscle strength with bone density in older adults.</p><p><strong>Methods: </strong>This systematic review, following PRISMA guidelines, involved a comprehensive search across seven databases from 2014 to April 2024. Included were observational studies in English and Indonesian on adults aged 60 and older. The AXIS tool assessed the risk of bias, and the GRADE framework evaluated the evidence quality. Study selection was independently reviewed, and consensus was reached through discussion.</p><p><strong>Results: </strong>Ten studies were included. For muscle mass and bone density, five studies showed a significant association, while four did not. For muscle strength and bone density, four of seven studies reported a significant association. However, the evidence quality was low due to inconsistency.</p><p><strong>Conclusions: </strong>The relationship between muscle mass, muscle strength, and bone density in older adults shows variability and inconsistent evidence.</p>","PeriodicalId":44729,"journal":{"name":"Annals of Geriatric Medicine and Research","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142510026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perioperative Risk Factors for Postoperative Delirium in Non-Dementia Older Patients after Non-Cardiac Surgery and Anesthesia: A Prospective Study.","authors":"Napat Wattanaboot, Warinporn Kuawatcharawong, Pattarada Permsakmesub","doi":"10.4235/agmr.24.0129","DOIUrl":"https://doi.org/10.4235/agmr.24.0129","url":null,"abstract":"<p><strong>Background: </strong>To investigate the incidence and perioperative risk factors for postoperative delirium (POD) in non-dementia older patients who underwent anesthesia for non-cardiac surgery.</p><p><strong>Methods: </strong>This prospective cohort study was conducted on 195 non-dementia older patients, aged 60 years or older, who were hospitalized after non-cardiac surgery and anesthesia. The Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) was used to evaluate the occurrence of POD. Incidence of POD was reported. We conducted univariate and multivariate logistic regression to identify the risk factors associated with POD.</p><p><strong>Results: </strong>195 patients were enrolled; 172 completed the study. POD occurred in seven patients within three days after anesthesia, which is a 4.1% incidence of POD. Multivariate logistic analysis showed arrhythmia, coagulopathy, urinary comorbidity, minimum intraoperative heart rate, and minimum post-anesthesia care unit (PACU) pain score as independent risk factors for POD. A minimum PACU pain score > 1 is the optimum cutoff pain score for developing POD, with a sensitivity of 85.7% and a specificity of 69.1%. The postoperative complication rate and in-hospital mortality were significantly higher for patients with POD compared to those without POD.</p><p><strong>Conclusion: </strong>The incidence of POD in the study population is 4.1%. Arrhythmia, coagulopathy, urinary comorbidity, minimum intraoperative heart rate, and minimum PACU pain score were independent risk factors for POD. The minimum PACU pain score is the strongest independent risk factor of POD. POD is associated with increased postoperative complications and in-hospital mortality rates in non-dementia older patients.</p>","PeriodicalId":44729,"journal":{"name":"Annals of Geriatric Medicine and Research","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142362197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preoperative Geriatric Characteristics Associated with Changes in Postoperative Cognitive Function and Quality of Life: a Prospective, Observational Analytic Multicenter Study.","authors":"Isngadi Isngadi, Aswoco A Asmoro, Nurul Huda, Taufiq A Siswagama, Nancy M Rehatta, Susilo Chandra, Djayanti Sari, Mayang I Lestari, Tjokorda Ga Senapathi, Haizah Nurdin, Belindo Wirabuana, Bintang Pramodana, Adinda P Pradhana, Novita Anggraeni, Kenanga M Sikumbang, Radian A Halimi, Zafrullah K Jasa, Akhyar Hamonangan Nasution, Mochamat Mochamat, Purwoko Purwoko","doi":"10.4235/agmr.24.0102","DOIUrl":"https://doi.org/10.4235/agmr.24.0102","url":null,"abstract":"<p><strong>Background: </strong>Changes in cognitive function are associated with increased depression and decreased quality of life (QOL). This study aimed to determine the relationship between the characteristics of geriatric patients and anesthetic management with changes in postoperative cognitive function and QOL of geriatric patients undergoing elective surgery.</p><p><strong>Methods: </strong>This prospective observational analytic multicenter study included patients aged ≥60 years who underwent elective surgery in hospitals in Indonesia. We used the whole sampling method and performed follow-up 30 days after surgery. Data were analyzed using bivariate chi-square and multivariate regression tests with a confidence interval of 95% and α=5%.</p><p><strong>Results: </strong>Among the 933 geriatric patients included in this study (55.0% female), most (59.8%) received general anesthesia. Factors including age (p<0.001, B=-0.374, odds ratio [OR]=0.688), body mass index (BMI) (p<0.05, B=0.129, OR=1.138), and physical status based on American Society of Anesthesiologists (ASA) classification (p<.001, B=-0.458, OR=0.633) were significantly associated with postoperative cognitive function. BMI (p<.001, B=-0.218, OR=1.244), absence of comorbidities (p<0.05, B=-0.312, OR=0.732), regional anesthesia (p<0.05, B=0.606, OR=1.883), and changes in cognitive function (p<0.05, B=0.288, OR=1.334) were significantly correlated with changes in postoperative QOL.</p><p><strong>Conclusion: </strong>Age, BMI, and ASA physical status were significantly associated with postoperative cognitive function in geriatric patients, whereas BMI, comorbidities, regional anesthesia, and changes in postoperative cognitive function were associated with QOL. These preoperative factors can predict postoperative cognitive function and QOL and may be useful during preoperative planning.</p>","PeriodicalId":44729,"journal":{"name":"Annals of Geriatric Medicine and Research","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142298052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Information and Communication Technology Use on the Executive Function of Older Adults Without Dementia: A Longitudinal Fixed-effect Analysis.","authors":"Hamin Lee, Sangmi Park, Seungho Han, Hyeondong Lee, Ickpyo Hong, Hae Yean Park","doi":"10.4235/agmr.24.0073","DOIUrl":"https://doi.org/10.4235/agmr.24.0073","url":null,"abstract":"<p><strong>Background: </strong>Impaired executive function is common in older adults. This study examined the causal relationship between the use of information and communication technology (ICT) and executive function in older adults over time.</p><p><strong>Methods: </strong>This study performed a secondary analysis of data from four waves (2016-2019) of the National Health and Aging Trends Study (NHATS). A fixed-effect analysis was conducted to examine the effects of ICT on the executive function of older adults without dementia aged ≥65 years. This study analyzed data from 3,334 respondents.</p><p><strong>Results: </strong>We observed significant positive effects of ICT use on executive function over time (standardized β = 0.043-0.045, 95% confidence interval [CI] = 0.001-0.043, p < 0.05).</p><p><strong>Conclusion: </strong>The current findings support the use of ICT as a protective approach to prevent decline in executive function in community-dwelling older adults.</p>","PeriodicalId":44729,"journal":{"name":"Annals of Geriatric Medicine and Research","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142356053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of sarcopenia on falls, mobility limitation, and mortality using the diagnostic criteria proposed in the Korean Working Group on Sarcopenia guideline.","authors":"Ga Yang Shim, Hak Chul Jang, Ki-Woong Kim, Jae-Young Lim","doi":"10.4235/agmr.24.0131","DOIUrl":"https://doi.org/10.4235/agmr.24.0131","url":null,"abstract":"<p><strong>Background: </strong>The recent published Korean Working Group on Sarcopenia (KWGS) guideline includes the concept of functional sarcopenia. The study investigated the prevalence of sarcopenia and its association with health-related adverse outcomes defined by the KWGS in community-dwelling older adults.</p><p><strong>Methods: </strong>Data were sourced from the Korean Longitudinal Study on Health and Aging, focusing on Koreans 65 aged and above. The definitions of sarcopenia and functional sarcopenia followed the KWGS. The risks of falls, mobility limitation, and death were analyzed using logistic regression and Cox proportional hazard.</p><p><strong>Results: </strong>Of the 594 participants, 145 (24.4%) were classified as having functional sarcopenia and 129 (12.0%) with sarcopenia. Both showed an increased prevalence with age. Functional sarcopenia had higher risks of mobility limitation [odds ratio (OR) 3.461, 95% confidence interval (95% CI) 1.956-6.121] and mortality [hazard ratio (HR) 1.775, 95% CI 1.229-2.564]. Sarcopenia was associated with falls [OR 7.376, 95% CI 1.500-36.272], mobility limitation [OR 2.057, 95% CI 1.172-3.611] and mortality [HR 1.512, 95% CI 1.054-2.169].</p><p><strong>Conclusion: </strong>Functional sarcopenia is a prevalent condition that is associated with mobility limitation and mortality in community-dwelling older adults. This highlights the clinical relevance of functional sarcopenia and supports its inclusion in sarcopenia diagnosis.</p>","PeriodicalId":44729,"journal":{"name":"Annals of Geriatric Medicine and Research","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142356054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health and Community Care Workers&apos; Knowledge and Perceptions of Social Prescribing in Singapore.","authors":"Li Feng Tan, Reshma Aziz Merchant","doi":"10.4235/agmr.24.0062","DOIUrl":"10.4235/agmr.24.0062","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to survey knowledge and perceptions of social prescribing (SP) amongst health and community care workers, and is a cross-sectional online survey conducted in November 2023.</p><p><strong>Methods: </strong>The survey on basic demographics, awareness, knowledge, and practices of SP was completed by 123 health and community care workers.</p><p><strong>Results: </strong>The mean age of respondents was 39.0 years. Nearly two-thirds had heard of SP. A lower proportion of acute hospital doctors (55.6%) and nurses (56.8%) had heard of SP compared with primary and subacute care doctors (75.0%). The majority agreed that SP benefits patients' mental health and reduces healthcare utilization. Primary care physicians, community nurses, and active ageing centres were the top three professionals selected as most responsible for SP by survey respondents. The most commonly cited barriers to SP were seniors' reluctance (63.4%), lacking knowledge on how to refer (59.3%), lack of time (44.7%), and cost to seniors (44.7%).</p><p><strong>Conclusion: </strong>Overall, health and community care workers demonstrated positive attitudes toward SP and were keen to refer patients for SP. However, additional efforts are needed to improve knowledge about how to refer to and provide training on SP.</p>","PeriodicalId":44729,"journal":{"name":"Annals of Geriatric Medicine and Research","volume":" ","pages":"352-361"},"PeriodicalIF":2.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11467523/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140898269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between Gait Speed and Balance Disorders in Older Adults from 12 High Andean Peruvian Communities, 2013-2019.","authors":"Fiorella Oliva-Zapata, Kimi Ururi-Cupi, Leslie Salazar-Talla, Ana L Alcantara-Diaz, Sofia Cuba-Ruiz, Diego Urrunaga-Pastor, Fernando M Runzer-Colmenares, José F Parodi","doi":"10.4235/agmr.24.0010","DOIUrl":"10.4235/agmr.24.0010","url":null,"abstract":"<p><strong>Background: </strong>Gait speed is associated with a higher prevalence of balance disorders in older adults residing at high altitudes. This study investigated this association in older adults from 12 high-altitude Andean Peruvian communities.</p><p><strong>Methods: </strong>We performed a secondary data analysis from an analytical cross-sectional study of adults &gt;60 years of age, residing in 12 high-altitude Andean Peruvian communities, enrolled between 2013 and 2019. The exposure and outcome variables were gait speed (categorized in tertiles), and balance disorders (defined as a functional reach value of ≤20.32 cm), respectively. We built generalized linear models of the Poisson family with a logarithmic link function and robust variances, and estimated crude prevalence ratios (cPR) and adjusted prevalence ratios (aPR) with 95% confidence intervals (CIs).</p><p><strong>Results: </strong>We analyzed 418 older adults; 38.8% (n=162) were male, and the mean age was 73.2±6.9 years. The mean gait speed and functional reach were 0.66±0.24 m/s and 19.9±6.48 cm, respectively. In the adjusted regression model, the intermediate (aPR=1.88; 95% CI, 1.39-2.55; p&lt;0.001) and low (aPR=2.04; 95% CI, 1.51-2.76; p&lt;0.001) tertiles of gait speed were associated with a higher prevalence of balance disorders.</p><p><strong>Conclusion: </strong>The intermediate and low tertiles of gait speed were associated with a higher prevalence of balance disorders among older adult residents of 12 high-altitude Andean communities. We recommend further research on the behavior of this association to propose interventions for these vulnerable groups and reduce the impact of geriatric conditions.</p>","PeriodicalId":44729,"journal":{"name":"Annals of Geriatric Medicine and Research","volume":" ","pages":"291-300"},"PeriodicalIF":2.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11467516/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141089260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between Dynapenia and Multimorbidity in Community-Dwelling Older Adults: A Systematic Review.","authors":"Hironori Ohinata, Shan Yun, Naoko Miyajima, Michiko Yuki","doi":"10.4235/agmr.24.0007","DOIUrl":"10.4235/agmr.24.0007","url":null,"abstract":"<p><p>Dynapenia and multimorbidity are common health problems affecting older adults. However, few studies have systematically reviewed the association between dynapenia and multimorbidity. Therefore, this systematic review aimed to provide a comprehensive overview of studies on the association between these conditions. We searched four electronic databases for relevant articles published in July 2023. The main inclusion criteria were the following: a description of dynapenia, which indicates loss of muscle strength, and a description of multimorbidity with two or more chronic diseases. Five studies met these inclusion criteria. In all five of these studies, the participants were community-dwelling older adults. All the studies showed an association between dynapenia and multimorbidity. The prevalence of dynapenia and multimorbidity ranged from 16% to 25.9%. The results of our systematic review demonstrated that dynapenia in older adults increases the risk of multimorbidity. We propose that interventions and reversible changes in dynapenia can prevent multimorbidity. (PROSPERO Registration No. CRD42023443282).</p>","PeriodicalId":44729,"journal":{"name":"Annals of Geriatric Medicine and Research","volume":" ","pages":"238-246"},"PeriodicalIF":2.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11467507/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140897911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}