发布求助
文献互助 智能选刊 最新文献

Tetrahedron Letters最新文献

筛选
英文 中文
ZnBr2 catalyzed sequential A3-coupling and intramolecular cyclization: One-pot synthesis of 3-aminofurans ZnBr2催化顺序a3偶联和分子内环化：一锅法合成3-氨基呋喃
IF 1.5 4区 化学
Tetrahedron Letters Pub Date : 2025-06-19 DOI: 10.1016/j.tetlet.2025.155718
Battini Geetha Rani , Sreedhar Gundekari , Kola Ramesh , Chandra Sekhar Vasam , Narasimha Swamy Thirukovela
{"title":"ZnBr2 catalyzed sequential A3-coupling and intramolecular cyclization: One-pot synthesis of 3-aminofurans","authors":"Battini Geetha Rani ,&nbsp;Sreedhar Gundekari ,&nbsp;Kola Ramesh ,&nbsp;Chandra Sekhar Vasam ,&nbsp;Narasimha Swamy Thirukovela","doi":"10.1016/j.tetlet.2025.155718","DOIUrl":"10.1016/j.tetlet.2025.155718","url":null,"abstract":"<div><div>ZnBr<sub>2</sub> salt was observed to be an effective catalyst to promote domino A<sup>3</sup>-coupling and intramolecular cyclization for the synthesis of 3-aminofurans from simple and commercially available α-ketoaldehydes, secondary amines, and terminal alkynes as starting materials. This method is compatible with several substrates and attractive, due to the formation of water as a by-product, operational simplicity, atom-economy, shorter reaction time, and inexpensive catalyst.</div></div>","PeriodicalId":438,"journal":{"name":"Tetrahedron Letters","volume":"168 ","pages":"Article 155718"},"PeriodicalIF":1.5,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144501394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
t-BuOLi-promoted Knoevenagel condensation: An efficient approach for synthesizing Arylid-BOX t- buoli促进Knoevenagel缩合：一种合成芳基酰胺- box的有效方法
IF 1.5 4区 化学
Tetrahedron Letters Pub Date : 2025-06-18 DOI: 10.1016/j.tetlet.2025.155706
Run He, Zilong Zhang, Yuxiang Zhou, Li Zeng, Lou Shi, Deqiang Liang
{"title":"t-BuOLi-promoted Knoevenagel condensation: An efficient approach for synthesizing Arylid-BOX","authors":"Run He,&nbsp;Zilong Zhang,&nbsp;Yuxiang Zhou,&nbsp;Li Zeng,&nbsp;Lou Shi,&nbsp;Deqiang Liang","doi":"10.1016/j.tetlet.2025.155706","DOIUrl":"10.1016/j.tetlet.2025.155706","url":null,"abstract":"<div><div>A <em>t</em>-BuOLi-promoted Knoevenagel condensation is reported, offering a straightforward method for the rapid construction of Arylid-BOX. This late-stage functionalization method of unsubstituted BOX ligands enables the rapid synthesis of a wide range of Arylid-BOX compounds. We speculate that the relatively small atomic radius of lithium ions contributes to the high yields of this reaction.</div></div>","PeriodicalId":438,"journal":{"name":"Tetrahedron Letters","volume":"168 ","pages":"Article 155706"},"PeriodicalIF":1.5,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144307133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mercaptan-free approach to the synthesis of Ethiprole, an insecticide 无硫醇合成杀虫剂乙虫乐的方法
IF 1.5 4区 化学
Tetrahedron Letters Pub Date : 2025-06-18 DOI: 10.1016/j.tetlet.2025.155713
Rachel Gundamalla , P. Naveen Reddy , RajashakerBantu , B.V. Subba Reddy
{"title":"Mercaptan-free approach to the synthesis of Ethiprole, an insecticide","authors":"Rachel Gundamalla ,&nbsp;P. Naveen Reddy ,&nbsp;RajashakerBantu ,&nbsp;B.V. Subba Reddy","doi":"10.1016/j.tetlet.2025.155713","DOIUrl":"10.1016/j.tetlet.2025.155713","url":null,"abstract":"<div><div>An efficient and practical method has been developed for the synthesis of a second-generation insecticide, ethiprole. The key step involved in this approach is the thiocynation of pyrazole ring at the 4th position, which was achieved using bromine and potassium thiocyanate in methanol. Another important step involves the one-pot conversion of thiocyanate into ethyl sulfide using ethyl bromide in the presence of a base. Each step in this synthesis was performed efficiently on a gram scale to produce high-quality product. This new synthetic strategy is simple, convenient and scalable.</div></div>","PeriodicalId":438,"journal":{"name":"Tetrahedron Letters","volume":"168 ","pages":"Article 155713"},"PeriodicalIF":1.5,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144329791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Total syntheses of anticancer Abietane Diterpenoids, (±)-Royleanone and (±)-Inuroyleanol via Lewis acid catalyzed Hydroarylation 路易斯酸催化氢化芳基化合成抗癌阿比烷二萜（±）-罗伊精酮和（±）-尿精醇
IF 1.5 4区 化学
Tetrahedron Letters Pub Date : 2025-06-18 DOI: 10.1016/j.tetlet.2025.155715
Badrinath N. Kakde , Suman Noskar , Saikat Bag , Alakesh Bisai
{"title":"Total syntheses of anticancer Abietane Diterpenoids, (±)-Royleanone and (±)-Inuroyleanol via Lewis acid catalyzed Hydroarylation","authors":"Badrinath N. Kakde ,&nbsp;Suman Noskar ,&nbsp;Saikat Bag ,&nbsp;Alakesh Bisai","doi":"10.1016/j.tetlet.2025.155715","DOIUrl":"10.1016/j.tetlet.2025.155715","url":null,"abstract":"<div><div>Herein we report a Lewis acid-catalyzed intramolecular hydroarylation strategy enabling an efficient synthesis of [6,6,6]-fused abietane diterpenoids sharing a trans-decalin motif. Using bismuth(III) triflate as an efficient metal triflate, the key intermediates were prepared in high yields, facilitating concise total syntheses of royleanone (<strong>1a</strong>) and inuroyleanone (<strong>1c</strong>), showcasing a scalable approach to complex natural product frameworks.</div></div>","PeriodicalId":438,"journal":{"name":"Tetrahedron Letters","volume":"168 ","pages":"Article 155715"},"PeriodicalIF":1.5,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144329790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An efficient synthesis of Indolo[3,2-c]coumarins by Pd-catalyzed intramolecular CH carbonylation pd催化分子内CH羰基化高效合成吲哚[3,2-c]香豆素
IF 1.5 4区 化学
Tetrahedron Letters Pub Date : 2025-06-17 DOI: 10.1016/j.tetlet.2025.155716
Hai-Bing Long, Xue-Hua Huang, Da-Xian You, Ye Liang, Jin-Bao Peng, Jia-Lei Yan, Ai-Jun Ma
{"title":"An efficient synthesis of Indolo[3,2-c]coumarins by Pd-catalyzed intramolecular CH carbonylation","authors":"Hai-Bing Long,&nbsp;Xue-Hua Huang,&nbsp;Da-Xian You,&nbsp;Ye Liang,&nbsp;Jin-Bao Peng,&nbsp;Jia-Lei Yan,&nbsp;Ai-Jun Ma","doi":"10.1016/j.tetlet.2025.155716","DOIUrl":"10.1016/j.tetlet.2025.155716","url":null,"abstract":"<div><div>Indolo[3,2-<em>c</em>]coumarins, characterized by their distinctive fused heterocyclic architecture, demonstrate significant biological activities in natural settings. In this study, we report a Pd-catalyzed intramolecular C<img>H carbonylation methodology for the synthesis of indolo[3,2-<em>c</em>]coumarins, and provide a straightforward approach for the total synthesis of natural product derivative and bioactive molecule of this class. This novel methodology provides a versatile platform for the comprehensive synthesis of indolo[3,2-<em>c</em>]coumarins.</div></div>","PeriodicalId":438,"journal":{"name":"Tetrahedron Letters","volume":"168 ","pages":"Article 155716"},"PeriodicalIF":1.5,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144338692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Highly sensitive turn-on fluorescent probe for the specific detection of cadaverine in shrimp 对虾尸体碱特异检测的高灵敏度开启荧光探针
IF 1.5 4区 化学
Tetrahedron Letters Pub Date : 2025-06-16 DOI: 10.1016/j.tetlet.2025.155714
Pei Liu , Wei Du , Yu-An Feng , Yu-Bin Su , Ya-Wen Wang , Jian Xiao , Yu Peng
{"title":"Highly sensitive turn-on fluorescent probe for the specific detection of cadaverine in shrimp","authors":"Pei Liu ,&nbsp;Wei Du ,&nbsp;Yu-An Feng ,&nbsp;Yu-Bin Su ,&nbsp;Ya-Wen Wang ,&nbsp;Jian Xiao ,&nbsp;Yu Peng","doi":"10.1016/j.tetlet.2025.155714","DOIUrl":"10.1016/j.tetlet.2025.155714","url":null,"abstract":"<div><div>An organic small-molecule fluorescent probe <strong>SWJT-36</strong> with an isophorone backbone for the specific detection of cadaverine (Cad), a shrimp spoilage marker, was developed. After the reaction the solution exhibited a distinct color change from pale yellow to deep amber under visible light irradiation, accompanied by intense red fluorescence emission. Particularly, <strong>SWJT-36</strong> exhibited high selectivity, low detection limit (2.655 μM), and fast response (t<sub>1/2</sub> = 13.8 min) for Cad. The reaction mechanism of <strong>SWJT-36</strong> and Cad was determined by mass spectrometry. And <strong>SWJT-36</strong> could be made into portable test strips that could detect Cad, thereby detecting the freshness of shrimp.</div></div>","PeriodicalId":438,"journal":{"name":"Tetrahedron Letters","volume":"168 ","pages":"Article 155714"},"PeriodicalIF":1.5,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144307134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Catalytic reductive annulation reactions of alkenes using dihaloalkanes 二卤代烷烃催化还原环化反应
IF 1.5 4区 化学
Tetrahedron Letters Pub Date : 2025-06-16 DOI: 10.1016/j.tetlet.2025.155705
Sayan Roy , Divya Garg , Christopher Uyeda
{"title":"Catalytic reductive annulation reactions of alkenes using dihaloalkanes","authors":"Sayan Roy ,&nbsp;Divya Garg ,&nbsp;Christopher Uyeda","doi":"10.1016/j.tetlet.2025.155705","DOIUrl":"10.1016/j.tetlet.2025.155705","url":null,"abstract":"<div><div>A nickel catalyst promotes the reductive annulation of alkenes using 1,3-dihalopropanes to provide substituted cyclopentanes. Mechanistic studies indicate that activation of the dihaloalkane occurs by a halogen-atom abstraction mechanism to generate a carbon-centered radical. Overall, the method provides direct access to saturated ring-systems from simple acyclic reaction partners.</div></div>","PeriodicalId":438,"journal":{"name":"Tetrahedron Letters","volume":"168 ","pages":"Article 155705"},"PeriodicalIF":1.5,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144290704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Iridium-catalyzed ester-directed oxidative coupling of aromatic esters and alkenes 铱催化芳香酯和烯烃的酯化氧化偶联
IF 1.5 4区 化学
Tetrahedron Letters Pub Date : 2025-06-14 DOI: 10.1016/j.tetlet.2025.155707
Elumalai Kumaran, Zhen Xuan Wong, Weng Kee Leong
{"title":"Iridium-catalyzed ester-directed oxidative coupling of aromatic esters and alkenes","authors":"Elumalai Kumaran,&nbsp;Zhen Xuan Wong,&nbsp;Weng Kee Leong","doi":"10.1016/j.tetlet.2025.155707","DOIUrl":"10.1016/j.tetlet.2025.155707","url":null,"abstract":"<div><div>The directing group-assisted, transition metal-catalyzed oxidative coupling of arenes with alkenes is a powerful tool for synthesizing functionalized alkenes. In this work, we report the iridium catalyzed oxidative coupling of aromatic esters with alkenes.</div></div>","PeriodicalId":438,"journal":{"name":"Tetrahedron Letters","volume":"168 ","pages":"Article 155707"},"PeriodicalIF":1.5,"publicationDate":"2025-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144307135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stereoselective synthesis, optical characterization, DFT, and metal ion detection of tetra p-tert-butylthiacalix[4]arene derivatives containing amide and thiamide fragments at lower rim 立体选择合成，光学表征，DFT，和金属离子检测四对叔丁基噻唑烷衍生物含酰胺和硫酰胺片段的下边缘
IF 1.5 4区 化学
Tetrahedron Letters Pub Date : 2025-06-14 DOI: 10.1016/j.tetlet.2025.155709
Mohamed Sharaf , Amr H. Moustafa , Mounier A.A. Mohamed , Moumen S. Kamel , Aly Abdou , Omran A. Omran
{"title":"Stereoselective synthesis, optical characterization, DFT, and metal ion detection of tetra p-tert-butylthiacalix[4]arene derivatives containing amide and thiamide fragments at lower rim","authors":"Mohamed Sharaf ,&nbsp;Amr H. Moustafa ,&nbsp;Mounier A.A. Mohamed ,&nbsp;Moumen S. Kamel ,&nbsp;Aly Abdou ,&nbsp;Omran A. Omran","doi":"10.1016/j.tetlet.2025.155709","DOIUrl":"10.1016/j.tetlet.2025.155709","url":null,"abstract":"<div><div><em>P</em>-tolylacetamide and <em>p</em>-tolylthioacetamide fragments are present in new <em>p-tert</em>-butylthiacalix[4]arenes at lower rims. <em>P-tert</em>-butylthiacalix[4]arene<strong>1</strong>reacted with 2-chloro (<em>p</em>-tolyl)acetamide to produce acetamide derivatives of thiacalixarene<strong>2–3</strong>, which are then thionated with Lawesson's reagent to produce thiacetamidethiacalixarenes derivatives <strong>4–5</strong>. FT-IR, NMR, metal ion detection, and the optical absorption spectrum characteristics of the novel thiacalixarenes derivative have all been used to analyze their structures. Density Functional Theory calculations revealed critical insights into the electronic, structural, and reactive properties of thiacalixarene derivatives (<strong>2–5</strong>). Compound <strong>2</strong> exhibited the highest nucleophilicity, lowest energy gap, and greatest reactivity towards metal uptake, underscoring its suitability for coordination chemistry. Computational analyses using the B3lyp/6-311++G** method matched well with experimental data, confirming the theoretical models. The IR spectra showed good agreement between experimental and theoretical results. Molecule electrostatic potential mapping highlighted possible sites for electrophilic interactions and stable metal-ligand bonding.</div></div>","PeriodicalId":438,"journal":{"name":"Tetrahedron Letters","volume":"168 ","pages":"Article 155709"},"PeriodicalIF":1.5,"publicationDate":"2025-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144279728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Catalytic asymmetric approach to floral odorant, (+)- and (−)-Florhydral （+）-和(−)-花水合醛的催化不对称研究
IF 1.5 4区 化学
Tetrahedron Letters Pub Date : 2025-06-11 DOI: 10.1016/j.tetlet.2025.155688
Debabrata Mondal , Dhruvilkumar Sureshkumar Patel , Vishnumaya Bisai
{"title":"Catalytic asymmetric approach to floral odorant, (+)- and (−)-Florhydral","authors":"Debabrata Mondal ,&nbsp;Dhruvilkumar Sureshkumar Patel ,&nbsp;Vishnumaya Bisai","doi":"10.1016/j.tetlet.2025.155688","DOIUrl":"10.1016/j.tetlet.2025.155688","url":null,"abstract":"<div><div>Catalytic asymmetric total synthesis of either enantiomer of floral odorant, i.e. (+)-florhydral® (<strong>1a</strong>) and (−)-florhydral® (<em>ent</em>-<strong>1a</strong>) has been achieved via a key catalytic asymmetric 3-isopropyl benzene boronic acid addition onto ethyl crotonate. Thus, an efficient two-step approach to both enantiomers of florhydral has been shown using 2 mol% Rh-(<em>S</em>)-BINAP (<strong>L1</strong>) as catalyst to achieve the product with a stereogenic center at the pseudo-benzylic position (up to 90 % ee).</div></div>","PeriodicalId":438,"journal":{"name":"Tetrahedron Letters","volume":"168 ","pages":"Article 155688"},"PeriodicalIF":1.5,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144255222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：604180095
Book学术官方微信