t-BuOLi-promoted Knoevenagel condensation: An efficient approach for synthesizing Arylid-BOX

IF 1.5 4区化学 Q3 CHEMISTRY, ORGANIC

Tetrahedron Letters Pub Date : 2025-06-18 DOI:10.1016/j.tetlet.2025.155706

Run He, Zilong Zhang, Yuxiang Zhou, Li Zeng, Lou Shi, Deqiang Liang

引用次数: 0

Abstract

A t-BuOLi-promoted Knoevenagel condensation is reported, offering a straightforward method for the rapid construction of Arylid-BOX. This late-stage functionalization method of unsubstituted BOX ligands enables the rapid synthesis of a wide range of Arylid-BOX compounds. We speculate that the relatively small atomic radius of lithium ions contributes to the high yields of this reaction.

查看原文本刊更多论文

t- buoli促进Knoevenagel缩合：一种合成芳基酰胺- box的有效方法

报道了一种t- buoli促进的Knoevenagel缩合，为快速构建芳基酰胺- box提供了一种简单的方法。这种未取代BOX配体的后期功能化方法可以快速合成各种芳基酰胺-BOX化合物。我们推测，锂离子相对较小的原子半径有助于该反应的高收率。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Tetrahedron Letters 化学-有机化学

CiteScore

3.50

自引率

5.60%

发文量

521

审稿时长

28 days

期刊介绍： Tetrahedron Letters provides maximum dissemination of outstanding developments in organic chemistry. The journal is published weekly and covers developments in techniques, structures, methods and conclusions in experimental and theoretical organic chemistry. Rapid publication of timely and significant research results enables researchers from all over the world to transmit quickly their new contributions to large, international audiences.