Journal of the World Federation of Orthodontists最新文献

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Effectiveness of clear aligner versus removable inclined plane in treatment of anterior crossbite in mixed dentition: A randomized clinical trial. 透明矫正器与可移动斜面治疗混合牙列前牙合的有效性:一项随机临床试验。
IF 2.6
Journal of the World Federation of Orthodontists Pub Date : 2024-12-19 DOI: 10.1016/j.ejwf.2024.11.001
Asmaa S Salem, Nehal F Albelasy, Ahmed A El-Bialy
{"title":"Effectiveness of clear aligner versus removable inclined plane in treatment of anterior crossbite in mixed dentition: A randomized clinical trial.","authors":"Asmaa S Salem, Nehal F Albelasy, Ahmed A El-Bialy","doi":"10.1016/j.ejwf.2024.11.001","DOIUrl":"https://doi.org/10.1016/j.ejwf.2024.11.001","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to compare the efficacy of clear aligners and removable inclined planes (RIP) in management of anterior crossbite in late mixed dentition patients using a 3D digital model.</p><p><strong>Materials and methods: </strong>Twenty-four patients with functional anterior crossbite, aged 8 to 12 years old, were randomly assigned to two parallel groups: the clear aligner (CA) group with a mean age of 10.74 ± 1.1 years, treated with clear aligner, and the RIP group with a mean age of 10.54 ± 1.06 years. Digital models were obtained for each patient before (T0) and after 4 months of starting the treatment (T1) using an intraoral scanner. The T0 to T1 digital model was superimposed to assess the primary outcome, labial movement of the maxillary incisors. For each model, the following secondary outcomes were evaluated: overbite, intermolar width (IMW), incisor leveling, arch perimeter (AP), and mesiodistal angulation. Data analysis included descriptive statistics, paired t tests, independent t tests, one-way ANOVA, and Tukey's HSD test.</p><p><strong>Results: </strong>There was no significant difference between CA and RIP groups regarding overjet, overbite, incisor leveling, and mesiodistal angulation of the maxillary incisors (P < 0.05). However, a significant difference was found between two groups in IMW, AP, and incisor superimposition (P < 0.05).</p><p><strong>Conclusions: </strong>The CA group showed a more significant increase in labial movement of maxillary incisors, IMW, and AP compared to the RIP group. However, both treatment protocols were effective in treating anterior crossbite. This study was recorded in the ClinicalTrials.gov database (identifier: NCT06015386).</p>","PeriodicalId":43456,"journal":{"name":"Journal of the World Federation of Orthodontists","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142872995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Periosteum response to static forces stimulates cortical drifting: A new orthopedic target 骨膜对静力的反应会刺激皮质漂移:新的矫形目标
IF 2.6
Journal of the World Federation of Orthodontists Pub Date : 2024-12-01 DOI: 10.1016/j.ejwf.2024.07.003
Mani Alikhani , Mona Alikhani , Chinapa Sangsuwon , Serafim P. Oliveira , Fanar Abdullah , Cristina C. Teixeira
{"title":"Periosteum response to static forces stimulates cortical drifting: A new orthopedic target","authors":"Mani Alikhani ,&nbsp;Mona Alikhani ,&nbsp;Chinapa Sangsuwon ,&nbsp;Serafim P. Oliveira ,&nbsp;Fanar Abdullah ,&nbsp;Cristina C. Teixeira","doi":"10.1016/j.ejwf.2024.07.003","DOIUrl":"10.1016/j.ejwf.2024.07.003","url":null,"abstract":"<div><h3>Background</h3><div>The mechanism of cortical bone adaptation to static forces is not well understood. This is an important process because static forces are applied to the cortical bone in response to the growth of soft tissues and during Orthodontic and Orthopedic corrections. The aim of this study was to investigate the cortical bone response to expanding forces applied to the maxilla.</div></div><div><h3>Methods</h3><div>Overall, 375 adult Sprague-Dawley rats were divided into three groups: 1) static force group, 2) static force plus stimulation group, and 3) sham group. In addition to static force across the maxilla, some animals were exposed to anti-inflammatory medication. Samples were collected at different time points and evaluated by micro-computed tomography, fluorescence microscopy, immunohistochemistry, and gene and protein analyses.</div></div><div><h3>Results</h3><div>The application of expansion forces to the maxilla increased inflammation in the periosteum and activated osteoclasts on the surface of the cortical plate. This activation was independent of the magnitude of tooth movement but followed the pattern of skeletal displacement. Bone formation on the surface of the cortical plate occurred at a later stage and resulted in the relocation of the cortical boundary of the maxilla and cortical drifting.</div></div><div><h3>Conclusions</h3><div>This study demonstrates that cortical bone adaptation to static forces originates from the periosteum, and it is an inflammatory-based phenomenon that can be manipulated by the clinician. Our findings support a new theory for cortical adaptation to static forces and an innovative clinical approach to promote cortical drifting through periosteal stimulation. Being able to control cortical drift can have a significant impact on clinical orthodontic and dentofacial orthopedics by allowing corrections of severe deformities without the need for maxillofacial surgery.</div></div>","PeriodicalId":43456,"journal":{"name":"Journal of the World Federation of Orthodontists","volume":"13 6","pages":"Pages 293-302"},"PeriodicalIF":2.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142113202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Orofacial dysfunction in cleft lip and palate patients using the nordic orofacial test-screening 使用北欧口腔测试筛查唇腭裂患者的口腔功能障碍。
IF 2.6
Journal of the World Federation of Orthodontists Pub Date : 2024-12-01 DOI: 10.1016/j.ejwf.2024.05.002
Neda Eslami , Erfan Bardideh , Pourya Tatari , Lohrasb Dehghani
{"title":"Orofacial dysfunction in cleft lip and palate patients using the nordic orofacial test-screening","authors":"Neda Eslami ,&nbsp;Erfan Bardideh ,&nbsp;Pourya Tatari ,&nbsp;Lohrasb Dehghani","doi":"10.1016/j.ejwf.2024.05.002","DOIUrl":"10.1016/j.ejwf.2024.05.002","url":null,"abstract":"<div><h3>Introduction</h3><div>The Nordic Orofacial Test-Screening (NOT-S) protocol serves as a widely recognized tool for assessing orofacial dysfunction comprehensively. This study aimed to compare orofacial dysfunction between unilateral (UCLP) and bilateral (BCLP) cleft lip and palate patients using the NOT-S.</div></div><div><h3>Materials and Methods</h3><div>This descriptive cross-sectional study enrolled 104 patients, comprising 72 with unilateral cleft lip and palate (UCLP) and 32 with bilateral cleft lip and palate (BCLP) referred to the cleft lip and palate clinic of Mashhad Dental School. Orofacial dysfunction was assessed using the Nordic Orofacial Test-Screening (NOT-S), which includes a structured interview and clinical examinations encompassing 6 domains each. Statistical analysis utilized Mann–Whitney, Fisher's exact, and Chi-square tests, with significance set at <em>P</em> &lt; 0.05.</div></div><div><h3>Results</h3><div>No significant differences were found in structured interview (<em>P</em> = 0.45), clinical examination (<em>P</em> = 0.45), or total NOT-S score (<em>P</em> = 0.11) between the two types of cleft lip and palate.</div></div><div><h3>Conclusion</h3><div>Based on NOT-S assessment, patients with unilateral (UCLP) and bilateral (BCLP) cleft lip and palate exhibited comparable orofacial dysfunctions. In the structured interview, the most prevalent issues were identified in the domain of chewing and swallowing for both cleft types. In clinical examination, unilateral cleft lip and palate patients commonly experienced facial problems at rest, while bilateral cleft lip and palate patients frequently encountered challenges with speaking. However, these differences were not statistically significant.</div></div>","PeriodicalId":43456,"journal":{"name":"Journal of the World Federation of Orthodontists","volume":"13 6","pages":"Pages 288-292"},"PeriodicalIF":2.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141724670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dr. Lawrence F. Andrews (1929–2024) 劳伦斯·f·安德鲁斯博士(1929-2024)
IF 2.6
Journal of the World Federation of Orthodontists Pub Date : 2024-12-01 DOI: 10.1016/j.ejwf.2024.11.004
Will A. Andrews DDS
{"title":"Dr. Lawrence F. Andrews (1929–2024)","authors":"Will A. Andrews DDS","doi":"10.1016/j.ejwf.2024.11.004","DOIUrl":"10.1016/j.ejwf.2024.11.004","url":null,"abstract":"","PeriodicalId":43456,"journal":{"name":"Journal of the World Federation of Orthodontists","volume":"13 6","pages":"Pages 310-311"},"PeriodicalIF":2.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142757532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring the potential applications of intraoral scanners in the treatment of cleft lip and palate deformity—A scoping review of literature 探索口内扫描仪在唇腭裂畸形治疗中的潜在应用--文献综述。
IF 2.6
Journal of the World Federation of Orthodontists Pub Date : 2024-12-01 DOI: 10.1016/j.ejwf.2024.06.001
Karthik Sennimalai , Madhanraj Selvaraj , Hamza Parvez Siddiqui , Nitika Monga , Kathijathul Hidhaya Sameemullah
{"title":"Exploring the potential applications of intraoral scanners in the treatment of cleft lip and palate deformity—A scoping review of literature","authors":"Karthik Sennimalai ,&nbsp;Madhanraj Selvaraj ,&nbsp;Hamza Parvez Siddiqui ,&nbsp;Nitika Monga ,&nbsp;Kathijathul Hidhaya Sameemullah","doi":"10.1016/j.ejwf.2024.06.001","DOIUrl":"10.1016/j.ejwf.2024.06.001","url":null,"abstract":"<div><h3>Background</h3><div>In the realm of cleft lip and palate (CLP) care, the integration of intraoral scanners (IOS) may offer a promising avenue, enabling precise digital imaging, record-keeping, treatment planning and execution. This scoping review aimed to explore the current applications of IOS in CLP patients and discuss potential future directions for optimizing the utilization of IOS in cleft care.</div></div><div><h3>Material and methods</h3><div>The review was registered apriori in the Open Science Framework (OSF) Registries (<span><span>https://doi.org/10.17605/OSF.IO/KPD34</span><svg><path></path></svg></span>). A systematic search was conducted across various databases like Ovid MEDLINE, PubMed, Cochrane Library, Embase, Web of Science, Scopus, Google Scholar, Grey literature, and Trial registries using a broad search strategy. The articles published in any language till December 20, 2023 were considered. Studies that demonstrated the application of intraoral scanning in nonsyndromic CLP patients were included. A validated sixteen-item content assessment tool was used to evaluate the included studies. Two independent reviewers performed data extraction and content assessment.</div></div><div><h3>Results</h3><div>Fifteen research studies and thirteen case reports/series were included in the final analysis. Various applications included capturing intraoral and extraoral images, scanning orthodontic study models, assessing dental changes, monitoring treatment changes related to nasoalveolar molding therapy, and fabricating appliances. The content assessment showed below-average mean scores of 34.79 ± 9.37% for research studies and 39.7 ± 0.14% for case reports/series. This can be attributed to insufficient information on scanning parameters, methodology, accuracy, patient outcomes, limitations, and potential solutions. The reproducibility of landmark identification in IOS was within 0.2 mm. Patients and caregivers preferred digital impressions over traditional alginate methods, reporting positive experiences in 84.8% of cases.</div></div><div><h3>Conclusion</h3><div>Intraoral scanners offer good clinical accuracy and validity in assessing dentofacial and nasolabial morphology in cleft patients. Adopting IOS can streamline clinical workflows, enhance treatment accuracy, and improve patient outcomes in managing cleft lip and palate.</div></div>","PeriodicalId":43456,"journal":{"name":"Journal of the World Federation of Orthodontists","volume":"13 6","pages":"Pages 265-278"},"PeriodicalIF":2.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141856779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Microplastics and orthodontic aligners: The concerns arising from the modernization of practice through polymers and plastics 微塑料和正畸矫治器:通过聚合物和塑料实现现代化实践引起的关注。
IF 2.6
Journal of the World Federation of Orthodontists Pub Date : 2024-12-01 DOI: 10.1016/j.ejwf.2024.10.001
Nearchos Panayi , Spyridon N. Papageorgiou , George Eliades , Theodore Eliades
{"title":"Microplastics and orthodontic aligners: The concerns arising from the modernization of practice through polymers and plastics","authors":"Nearchos Panayi ,&nbsp;Spyridon N. Papageorgiou ,&nbsp;George Eliades ,&nbsp;Theodore Eliades","doi":"10.1016/j.ejwf.2024.10.001","DOIUrl":"10.1016/j.ejwf.2024.10.001","url":null,"abstract":"<div><div>Plastic aligners have transformed orthodontics, offering a discreet, comfortable, and aesthetically pleasing alternative to traditional fixed appliances. While they have advantages over fixed appliances, they come with environmental and health concerns due to the use of nonbiodegradable plastics, such as the leaching of Bisphenol-A (BPA) and microplastics that can impact human health directly through ingestion. Studies have shown that plastic aligners release microplastics during use, raising concerns about their potential health effects and environmental pollution. The potential health effects of ingested microplastics extend beyond gut microbiota disruption to impact various systems in the body. Research suggests that microplastic exposure can lead to respiratory complications, cardiovascular risks, and implications for brain health and cognitive function. The mechanisms of microplastic uptake into the body through inhalation, ingestion, and skin contact are essential for understanding how these particles interact with human tissues and organs. By prioritizing patient safety, responsible practices, and advancing scientific knowledge the orthodontic community can work towards mitigating the potential health impacts associated with microplastic exposure from aligners.</div></div>","PeriodicalId":43456,"journal":{"name":"Journal of the World Federation of Orthodontists","volume":"13 6","pages":"Pages 259-264"},"PeriodicalIF":2.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142682224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transforming orthodontic care: Integrating the biopsychosocial model for optimal patient outcomes 转变正畸护理:整合最佳患者结果的生物心理社会模型
IF 2.6
Journal of the World Federation of Orthodontists Pub Date : 2024-12-01 DOI: 10.1016/j.ejwf.2024.11.002
Vinod Krishnan (Editor-in-Chief)
{"title":"Transforming orthodontic care: Integrating the biopsychosocial model for optimal patient outcomes","authors":"Vinod Krishnan (Editor-in-Chief)","doi":"10.1016/j.ejwf.2024.11.002","DOIUrl":"10.1016/j.ejwf.2024.11.002","url":null,"abstract":"","PeriodicalId":43456,"journal":{"name":"Journal of the World Federation of Orthodontists","volume":"13 6","pages":"Pages 257-258"},"PeriodicalIF":2.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142757531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prediction of patient cooperation before orthodontic treatment: Handwriting and artificial intelligence 预测正畸治疗前患者的合作情况:手写和人工智能
IF 2.6
Journal of the World Federation of Orthodontists Pub Date : 2024-12-01 DOI: 10.1016/j.ejwf.2024.07.004
Farhad Salmanpour, Hasan Camcı
{"title":"Prediction of patient cooperation before orthodontic treatment: Handwriting and artificial intelligence","authors":"Farhad Salmanpour,&nbsp;Hasan Camcı","doi":"10.1016/j.ejwf.2024.07.004","DOIUrl":"10.1016/j.ejwf.2024.07.004","url":null,"abstract":"<div><h3>Background</h3><div>The purpose of this study was to compare the success of various convolutional neural network (CNN) models trained with handwriting samples in predicting patient cooperation.</div></div><div><h3>Methods</h3><div>A total of 237 (147 female and 90 male, mean age 14.94 ± 2.4) patients undergoing fixed orthodontic treatment were included in the study. In the 12th month of treatment, participants were divided into two groups based on the patient cooperation scale: cooperative or noncooperative. Then, for each patient, handwriting samples were obtained. Artificial neural network models were used to classify the patients as cooperative or noncooperative using the collected data. The accuracy, precision, recall, and F1-score values of nine different CNN models were compared.</div></div><div><h3>Results</h3><div>By overall success rate, InceptionResNetV2 (Accuracy: 72.0%, F1-score: 0.649) and NasNetMobil (Accuracy: 70.0%, F1-score: 0.417) were the two most effective CNN models. The two models with the lowest success rate were DenseNet121 (Accuracy: 59.0%, F1-score: 0.424) and ResNet50V2 (Accuracy: 46.0%, F1-score: 0.286). The success rates of the other five models were comparable.</div></div><div><h3>Conclusions</h3><div>The artificial intelligence models trained with handwriting samples are not sufficiently accurate for clinical application in cooperation prediction.</div></div>","PeriodicalId":43456,"journal":{"name":"Journal of the World Federation of Orthodontists","volume":"13 6","pages":"Pages 303-309"},"PeriodicalIF":2.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142134132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trends and insights in animal and biomedical research: A 5-year scientometric analysis of orthodontic peer-reviewed journals 动物和生物医学研究的趋势和见解:对正畸同行评审期刊的五年科学计量分析。
IF 2.6
Journal of the World Federation of Orthodontists Pub Date : 2024-12-01 DOI: 10.1016/j.ejwf.2024.08.003
Hams H. Abdelrahman , Yomna M. Yacout , Dina G. Hassan , Mohamed G. Hassan , Gamal A. Hassan
{"title":"Trends and insights in animal and biomedical research: A 5-year scientometric analysis of orthodontic peer-reviewed journals","authors":"Hams H. Abdelrahman ,&nbsp;Yomna M. Yacout ,&nbsp;Dina G. Hassan ,&nbsp;Mohamed G. Hassan ,&nbsp;Gamal A. Hassan","doi":"10.1016/j.ejwf.2024.08.003","DOIUrl":"10.1016/j.ejwf.2024.08.003","url":null,"abstract":"<div><h3>Background</h3><div>Biomedical research plays a critical role in advancing orthodontic innovations by identifying new targets for therapeutic interventions and developing more effective, personalized orthodontic treatment. This study evaluates the major contributors and trends in animal-related orthodontic research over the past 5 years (2017–2023).</div></div><div><h3>Methods</h3><div>All animal-related studies published in the eight orthodontic journals listed in the 2022 Journal Citation Reports between January 2017 and June 2023 were retrieved from the Web of Science Core Collection. After examination, the following bibliometric data were extracted from each article: title, authors, affiliations, geographic origin, year of publication, journal name, and keywords. Multiple bibliometric software packages including Biblioshiny R-package software, Datawrapper, and Datasmith were used to analyze different bibliometric outcomes.</div></div><div><h3>Results</h3><div>A total of 3669 articles were screened from which 266 were selected and included in the analysis. The annual growth rate of production exhibited a decline of 11.18%. Most of the included studies focused on orthodontic tooth movement (32.3%), mainly utilizing rat models (50%). Although the United States accounted for the highest number of publications (n = 236), the trend in funded research showed a decreasing trajectory over time, with notably limited funding from the National Institutes of Health.</div></div><div><h3>Conclusion</h3><div>This study reveals a declining trend in overall animal-related orthodontic research, highlighted by a significant decrease in National Institutes of Health funding over time. To address this gap, academic institutions and professional organizations should support initiatives fostering biomedical orthodontic research.</div></div>","PeriodicalId":43456,"journal":{"name":"Journal of the World Federation of Orthodontists","volume":"13 6","pages":"Pages 279-287"},"PeriodicalIF":2.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142297900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of restraint stress and orthodontic treatment on physical and psychological states in rats. 约束应激与正畸治疗对大鼠身心状态的影响。
IF 2.6
Journal of the World Federation of Orthodontists Pub Date : 2024-11-27 DOI: 10.1016/j.ejwf.2024.10.002
Ye Cheng, Hua Nie, Jun Qian, Jiangyue Lu, Yanfen Li, Huang Li, Fuhua Yan
{"title":"Effects of restraint stress and orthodontic treatment on physical and psychological states in rats.","authors":"Ye Cheng, Hua Nie, Jun Qian, Jiangyue Lu, Yanfen Li, Huang Li, Fuhua Yan","doi":"10.1016/j.ejwf.2024.10.002","DOIUrl":"https://doi.org/10.1016/j.ejwf.2024.10.002","url":null,"abstract":"<p><strong>Objective: </strong>To explore the effects of restraint stress and orthodontic tooth movement on the body weight and behavior of rats.</p><p><strong>Materials and methods: </strong>Twenty 8-week-old male Wistar rats were randomly divided into four groups: sham stress nonorthodontic (CC), sham stress orthodontic (CO), stress nonorthodontic (SC) and stress orthodontic (SO). Rats in the stress group were subjected to restraint stress for 21 days, and those in the orthodontic group received molar retraction on days 8 to 21 (D8-D21). The weights of the rats were measured, and behavioral tests were performed on D0, D10, and D20. Serum corticosterone levels in the rats were measured on D0, D4, D8, D12, D16, and D21.</p><p><strong>Results: </strong>The weights of rats in the CO, SC, and SO groups were significantly lower than those in the CC group. In the open-field test, the number of times the rats entered the central zone in the CC group was significantly higher than that in the other three groups. In the elevated plus maze test, at D10, the number of times the rats entered the open arms in the SO, SC, and CO groups was significantly lower than that in the CC group. From D12, the serum corticosterone levels in the CO, SC, and SO groups were significantly higher than those in the CC group.</p><p><strong>Conclusions: </strong>Both restraint stress and orthodontic tooth movement interventions may have adverse effects on weight, behavior, and neuroendocrine responses. However, overlapping the two intervention methods did not increase the magnitude of the effect.</p>","PeriodicalId":43456,"journal":{"name":"Journal of the World Federation of Orthodontists","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142751981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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