Veterinary Biomedical and Clinical Journal最新文献

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The Potentials of Robusta Coffee Seed Extract as Antioxidant on Kidney Histopathology in Mice Exposed to Monosodium Glutamate 罗布斯塔咖啡种子提取物对谷氨酸钠暴露小鼠肾脏组织病理学的抗氧化作用
Veterinary Biomedical and Clinical Journal Pub Date : 2023-01-31 DOI: 10.21776/ub.vetbioclinj.2023.005.01.3
Feby Dwi Wisudawati, Nove Hidajati, F. Fikri, K. P. Santoso, A. L. Saputro, M. T. E. Purnama
{"title":"The Potentials of Robusta Coffee Seed Extract as Antioxidant on Kidney Histopathology in Mice Exposed to Monosodium Glutamate","authors":"Feby Dwi Wisudawati, Nove Hidajati, F. Fikri, K. P. Santoso, A. L. Saputro, M. T. E. Purnama","doi":"10.21776/ub.vetbioclinj.2023.005.01.3","DOIUrl":"https://doi.org/10.21776/ub.vetbioclinj.2023.005.01.3","url":null,"abstract":"The purpose of this study was to determine the potential of administration robusta coffee extract as an antioxidant on the renal histopathology in mice exposed to monosodium glutamate (MSG) orally. This study used 20 adult male rats with Balb C strain divided into 5 experimental groups, namely K + (MSG 0.12 mg / head and Vitamin C 6 mg/mice), K- (MSG 0.12 mg/mice and Sodium carboxymethyl cellulose (CMC Na) 0,1 ml/mice), P1 (MSG 0.12 mg/mice and Robusta coffee extract 0.1 mg/mice), P2 (MSG 0.12 mg/mice and Robusta coffee extract 0.2 mg/mice), and P3 (MSG 0.12 mg/mice and 0.4 mg Robusta coffee extract mg/mice). The experimental group was treated every day at intervals between MSG and Vitamin C, CMC Na, and Robusta coffee extract for 60 min, the treatment was carried out for 42 days. Kidney histopathology scores were analyzed using the Saphiro-Wilk and Levene test to evaluate homogeneity, followed by the Kruskal Wallis test. The results of the Saphiro Wilk and Levene statistical analysis obtained p<0.05, thus the data continued with the Kruskal Wallis test scores of kidney cell damage obtained 0.043 which showed that the data were significant. The mean score of kidney cell damage in the treatment groups was K+ 1.60; K- 1.63; P1 1.70; P2 1.63; and P3 1.73. The conclusion is that Robusta coffee bean extract did not show a decrease in kidney cell damage that was different between treatment groups. Further research is needed to find out about the effect of different dosages of Robusta Coffee Extract to different organs","PeriodicalId":432813,"journal":{"name":"Veterinary Biomedical and Clinical Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125928637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Feline Calicivirus Infection with Chronic Stomatitis, Rhinitis and Otitis in a Bengal Cat in Indonesia 印度尼西亚孟加拉猫慢性口炎、鼻炎和中耳炎的猫杯状病毒感染
Veterinary Biomedical and Clinical Journal Pub Date : 2022-12-31 DOI: 10.21776/ub.vetbioclinj.2022.004.02.1
I. P. Hermawan, Donna Marie Leo
{"title":"Feline Calicivirus Infection with Chronic Stomatitis, Rhinitis and Otitis in a Bengal Cat in Indonesia","authors":"I. P. Hermawan, Donna Marie Leo","doi":"10.21776/ub.vetbioclinj.2022.004.02.1","DOIUrl":"https://doi.org/10.21776/ub.vetbioclinj.2022.004.02.1","url":null,"abstract":"The purpose of this case study was to describesthe infection withfeline calicivirus manifested aschronic stomatitis, rhinitisand otitis ina Bengal cat. Acat was presented to the clinic due to inappetence, weakness, and frequent vomiting. It hadnever been vaccinated, and never been given anthelmintic. It had an openwound on itsback,andpurulent dischargewas appearing inthe earand nose. Usingan antigen testkit, Feline Calicivirus was tested positivefor infection with Feline calicivirus.Therapies were givento relieve clinical signshowever, thepatient could not be saved. Prevention of feline caliciviruscould be done by vaccination, as well as maintainingcleanliness of housingand equipment","PeriodicalId":432813,"journal":{"name":"Veterinary Biomedical and Clinical Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116790842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Case Study: Removal of Calculi in The Bladder using Cystotomy Method in Female Pomeranian Mix Pekingese Dog at Winadi Vet Animal Clinic Malang 个案研究:在玛琅威纳迪兽医诊所用膀胱切开术切除雌性波美拉尼亚混合北京哈巴狗膀胱结石
Veterinary Biomedical and Clinical Journal Pub Date : 2022-12-31 DOI: 10.21776/ub.vetbioclinj.2022.004.02.3
Fenti Nursafitri, D. Vidiastuti, Winda Syafitri
{"title":"Case Study: Removal of Calculi in The Bladder using Cystotomy Method in Female Pomeranian Mix Pekingese Dog at Winadi Vet Animal Clinic Malang","authors":"Fenti Nursafitri, D. Vidiastuti, Winda Syafitri","doi":"10.21776/ub.vetbioclinj.2022.004.02.3","DOIUrl":"https://doi.org/10.21776/ub.vetbioclinj.2022.004.02.3","url":null,"abstract":"Urolithiasis is a disease caused by calculi, crystals, or excessive sediment in the urinary tract, which is generallycomposed of one or more types of minerals such as struvite, calcium oxalate, calcium phosphate, uric acid, andcystine.A10-year-oldfemalePomeranianmixPekingesedogwasreferredtoWinadiVetAnimalClinicMalangwith clinical signs of dysuria, strangury, and hematuria. The physical examination findings were lethargy, caudalabdominal pain, and bladder distension. Radiological examination results indicated distension in the urinarybladder containing two stones occupying withclearmarginsand radiopaque-likeopacity,withlengths of3.44cmand 3.35 cm, respectively. Cystotomy to remove the calculi was performed by incision on the midline.The urinary bladder was closed using a two-layer closure suture type, the first layer used simple interrupted, andthe second layer used simple continuous suture with 3-0 polyglactin (Vicryl®) suture. The animal recovered onthefourteenth day aftersurgery","PeriodicalId":432813,"journal":{"name":"Veterinary Biomedical and Clinical Journal","volume":"98 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116103830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surgical Management of Niktitan Membrane Prolapse in Beagle Dogat DNA Animal Clinic Bogor 比格犬DNA动物诊所尼克提膜脱垂的外科治疗
Veterinary Biomedical and Clinical Journal Pub Date : 2022-12-31 DOI: 10.21776/ub.vetbioclinj.2022.004.02.5
Erina Bidari Utomo, M. A. Lesmana, Nofan Rickyawan, Gegana Wimaldy Airlangga, S. D. Waspada
{"title":"Surgical Management of Niktitan Membrane Prolapse in Beagle Dogat DNA Animal Clinic Bogor","authors":"Erina Bidari Utomo, M. A. Lesmana, Nofan Rickyawan, Gegana Wimaldy Airlangga, S. D. Waspada","doi":"10.21776/ub.vetbioclinj.2022.004.02.5","DOIUrl":"https://doi.org/10.21776/ub.vetbioclinj.2022.004.02.5","url":null,"abstract":"An 11-year-old female Beagle dog weighing 18 Kg was brought to the clinic with redness discoloration in her right eye, a cherry like lump, and ocular discharge. Based on the clinical signs, the diagnosis was a prolaps of the nictitating membrane or “Cherry Eye” with a fausta prognosis. The treatment was a surgery using the Morgan Pocket method to maintain the mobility of the nictitating membrane and lymphoid tissue. The postoperative therapy given was the anti-inflammatory drug meloxicam 0.2 mg/kg once a day orally and gentamicin eye ointment (Genoint 0.3% Eye Oint) topically twice a day. Five days after the surgery and treatment, the dog's eyes had improved, and there was no lump observable","PeriodicalId":432813,"journal":{"name":"Veterinary Biomedical and Clinical Journal","volume":"25 1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128727307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy of Shallots Infusion (Allium Cepa L.) as an Antidiarrhea in Mice (Mus Musculus) 葱冲剂对小鼠止泻作用的研究
Veterinary Biomedical and Clinical Journal Pub Date : 2022-12-31 DOI: 10.21776/ub.vetbioclinj.2022.004.02.2
A. S. Purohita, A. Mustika, L. N. Sutardi, Amaq Fadholly
{"title":"Efficacy of Shallots Infusion (Allium Cepa L.) as an Antidiarrhea in Mice (Mus Musculus)","authors":"A. S. Purohita, A. Mustika, L. N. Sutardi, Amaq Fadholly","doi":"10.21776/ub.vetbioclinj.2022.004.02.2","DOIUrl":"https://doi.org/10.21776/ub.vetbioclinj.2022.004.02.2","url":null,"abstract":"Shallots have been used for generations as traditional medicine, one of which is used in the treatment of diarrhea. This study determinedthe antidiarrheal activity of the shallot bulbs using intestinal protection and intestinal transit methods, and to determine the effective concentration that gives the best antidiarrheal effect in mice. This study used thirtymiceanddivided into six groups.The negativecontrol groupwas givenTween 80 (1%), positivecontrol group was given LoperamideHCl, and four various concentrations of shallot infusion treatment groups (1.25%, 2.5%, 5%, and 10 %). The treatment was given by the oral route. The parameters used in the intestinal protection method were frequency of defecation and fecesconsistency, while in intestinal transit method the parameters used were the percentage ratio of the marker trajectories compared to the overall length of the intestine. The results showed that the 1.25% concentration of shallot infusion indicatedthe best antidiarrheal activity and had a smaller ratio or stronger inhibition tointestinal peristalticcompared toall other concentrations, 2.5%, 5%, dan 10%. We concludedthat shallot bulbs infusion with a concentration of 1.25% has the most effective anti-diarrheal effect. This research can be continued by measurement of other diarrheal parameters such asstool weight, as well as start and stop time of diarrhea to further clarify the anti-diarrheal potential of shallot bulb infusion","PeriodicalId":432813,"journal":{"name":"Veterinary Biomedical and Clinical Journal","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121870348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Case Report Foot and Mouth Disease (FMD) in Beef Cattle in Central Bangka Regency, Bangka Belitung Islands Province 邦加勿里洞群岛省邦加县中部肉牛口蹄疫病例报告
Veterinary Biomedical and Clinical Journal Pub Date : 2022-12-31 DOI: 10.21776/ub.vetbioclinj.2022.004.02.4
Inawati Wulandani
{"title":"Case Report Foot and Mouth Disease (FMD) in Beef Cattle in Central Bangka Regency, Bangka Belitung Islands Province","authors":"Inawati Wulandani","doi":"10.21776/ub.vetbioclinj.2022.004.02.4","DOIUrl":"https://doi.org/10.21776/ub.vetbioclinj.2022.004.02.4","url":null,"abstract":"Foot and mouth disease (FMD) is a contagious animal disease with high morbidity and enormous economic losses. This disease is caused by the type A virus from the Picornaviride family, which can attack various species of animals with an even number of nails. Foot and mouth disease was endemic in Central Bangka Regency from the beginning of May to September 2022, and affected cattle reached 1,309 heads. This paper aimed todetermine the prevalanceof cases, existing disease symptoms, and recovery response to treatment. The method used was collecting data from Central Bangka Regency animal health officers from early May to September 14, 2022. The result was that the prevalence of FMD cases in the Pangkalan Baru sub-district was 44.60%, Simpang Katis sub-district 49.70%, the Namang sub-district 6.10%, the Koba sub-district 6.80% and Sungaiselan sub-district 0.54% Symptoms experienced by the animals include hypersalivation/mouth discharge, anorexia, blistering lesions on the tongue, lips, gums and between rashes. Drug therapy includes antibiotics, antipyretics, vitamins, non-steroidal anti-inflammatories, feed premixes as well as routine spraying of disinfectants. Based on the report of the Field Veterinarian, the therapy provided good results without recurrence, and the clinical cure rate reached 96.72%","PeriodicalId":432813,"journal":{"name":"Veterinary Biomedical and Clinical Journal","volume":"108 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131455382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Case Study: Pyothorax in Domestic Short Hair Cat 个案研究:家养短毛猫的脓胸
Veterinary Biomedical and Clinical Journal Pub Date : 2022-06-27 DOI: 10.21776/ub.vetbioclinj.2022.004.01.1
N. Hasanah, Upakarti Mentari, Siti Zaenab, Zulfa Ichsanniyati
{"title":"Case Study: Pyothorax in Domestic Short Hair Cat","authors":"N. Hasanah, Upakarti Mentari, Siti Zaenab, Zulfa Ichsanniyati","doi":"10.21776/ub.vetbioclinj.2022.004.01.1","DOIUrl":"https://doi.org/10.21776/ub.vetbioclinj.2022.004.01.1","url":null,"abstract":"One of the diseases caused by pathogenic microbial infections is pyothorax. Pyothorax, also known as thoracic empyema, accumulates purulent exudates in the pleural space. This study aims to understand the diagnosis and therapy of pyothorax in Domestic Short Hair (DSH) cats. A male DSH cat came with a harsh breath condition or acute dyspnea. The cat was breathing more rapidly, having to make more effort to breathe. The anamnesis showed that the patient had a cough history and repeated with a dyspnea condition. Some diagnoses were radiographic examination (x-ray) and laboratory tests such as complete blood cell, blood chemistry, cytology, and bacterial culture. Result of radiography examination and laboratory examination showed that increasing of white blood cells or leukocytosis in complete blood cell test, fluid loss (dehydration) in the blood chemistry test, radiography (x-ray) imaging saw the abnormalities in the lungs that was a white color (radio-opaque) and looked homogeneous. Thoracocentesis founded pleural effusions in the form of pus/pyo, cytology examination found polymorphonuclear cells (PMN) neutrophils and mononuclear cells (MN), and the result of pus bacterial culture was Acinobacter baumannii. The examination results in patients showed positive pyothorax with causal of Acinobacter baumanii. Antibiotic therapy sensitive to Acinobacter baumanii had been proven effective until the patient recovered. The antibiotics for therapy started with 10 mg/kg BW of Enrofloxacin, 20 mg/kg BW of Meropenem, and 20 mg/kg BW of Tigecycline. Tigecycline has proven to be effective until the cat recovers.","PeriodicalId":432813,"journal":{"name":"Veterinary Biomedical and Clinical Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130776983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Identification and Morphometric Analysis of Toxocara cati in Domestic Cat at Ontosenovet Animal Clinic Malang 马琅Ontosenovet动物诊所家猫猫弓形虫鉴定及形态计量学分析
Veterinary Biomedical and Clinical Journal Pub Date : 2022-06-27 DOI: 10.21776/ub.vetbioclinj.2022.004.01.5
E. Soegiarto, R. Yesica, D. Antika
{"title":"Identification and Morphometric Analysis of Toxocara cati in Domestic Cat at Ontosenovet Animal Clinic Malang","authors":"E. Soegiarto, R. Yesica, D. Antika","doi":"10.21776/ub.vetbioclinj.2022.004.01.5","DOIUrl":"https://doi.org/10.21776/ub.vetbioclinj.2022.004.01.5","url":null,"abstract":"Toxocariasis is a worm disease caused by infection of Toxocara cati. This study aims to identify the etiology, clinical symptoms, diagnosis, morphometry of eggs and worms in domestic cats at the Ontosenovet Animal Clinic Malang. The results of physical examination reveal enlargement of the abdomen, dull hair and hair loss. Hematological examination results showed a decrease in platelets, RDW-VC, and RDW-SD, an increase in lymphocytes, and MCHC. Examination of feces and worms and eggs is carried out at the Parasitology Laboratory of the Faculty of Veterinary Medicine, Universitas Brawijaya. Stool examination is carried out using native and floating methods which showed the presence of worm eggs in the second method. The eggs show a slightly elongated or oval shape, thick walls, and a mottled surface. Worm eggs have an average length of 71,61 μm and a width of 59,87 μm. Worms obtained from cat vomit were then made preparations with Acetocarmine staining. The results of worm observations show three lips on the anterior, posterior end of digitiform and curved to the ventral. The results of morphometric measurements of adult T. cati show that the diameter of the worm, the length of the posterior end of the worm, and the width of the lips obtained an average of 754,14 μm, 545,19 μm, and 314,87 μm respectively. Overall body lengths of worm samples 1, 2, and 3 are 7,50 cm, 8,70 cm, and 7,80 cm with an average of 8,00 cm. Based on the examination the cat had toxocariasis due to Toxocara cati. The therapy given is an anthelmintic Drontal (¾ tablet) which contained 20 mg praziquantel and 80 mg pyrantel.","PeriodicalId":432813,"journal":{"name":"Veterinary Biomedical and Clinical Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130960934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Infection with Strongyle in Bali Cattle (Bos sondaicus) in Kupang Regency 姑邦县巴厘牛(bossondaicus) Strongyle感染
Veterinary Biomedical and Clinical Journal Pub Date : 2022-06-27 DOI: 10.21776/ub.vetbioclinj.2022.004.01.3
V. Mbula, Aji Winarso, M. Sanam
{"title":"Infection with Strongyle in Bali Cattle (Bos sondaicus) in Kupang Regency","authors":"V. Mbula, Aji Winarso, M. Sanam","doi":"10.21776/ub.vetbioclinj.2022.004.01.3","DOIUrl":"https://doi.org/10.21776/ub.vetbioclinj.2022.004.01.3","url":null,"abstract":"Gastrointestinal parasitic worm infection is one of the most common disease agents found in Bali cattle. The large number of eggs found, indicates the prevalence of nematodiasis in a region. This study aims to calculate the prevalence and analyze the relationship of the degree of infection with risk factors for the incidence of gastrointestinal nematodiasis in Bali cattle in Kupang Regency. This study uses across-sectional study with simple random sampling and the number of samples taken is 171 samples. Microscopic examination of faecal samples uses the McMaster method to identify gastrointestinal nematode eggs based on their type. Data analysis uses the Chi-Square test to determine the relationship ofthe significance of risk factors. Based on the results of research, Strongyle type nematodes have a prevalence value of 46.78%. Age and sex did not show an influence on infection risk.","PeriodicalId":432813,"journal":{"name":"Veterinary Biomedical and Clinical Journal","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129541892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Torbangun Leaf (Coleus ambonicus, L.) Extract Feeding on Cisplatin-Induced in Wistar Rats (Rattus norvegicus) 托尔班冈叶(Coleus ambonicus, L.)的药效顺铂诱导褐家鼠提取液饲喂
Veterinary Biomedical and Clinical Journal Pub Date : 2022-06-27 DOI: 10.21776/ub.vetbioclinj.2022.004.01.2
R. Solfaine, M. Supriyanto
{"title":"Effect of Torbangun Leaf (Coleus ambonicus, L.) Extract Feeding on Cisplatin-Induced in Wistar Rats (Rattus norvegicus)","authors":"R. Solfaine, M. Supriyanto","doi":"10.21776/ub.vetbioclinj.2022.004.01.2","DOIUrl":"https://doi.org/10.21776/ub.vetbioclinj.2022.004.01.2","url":null,"abstract":"This study aimed to analyze the effect of torbangun leaf extract (Coleus ambonicus, L.) on kidney histopathology in cisplatin-induced Wistar rats. The design used was Completely Randomized Design (CRD) with three different treatments and six repetitions. The rats used were 18 male Wistar (Rattus norvegicus) rats, bodyweight 150-200 grams and 2-3 months of age. Treatment P0 for Wistar rats given aquadest ad libitum, P1 for Wistar rats injected with Cisplatin on day 4, intraperitoneally at a dose of 7 mg/kg with 1% of CMC NA suspension and P2 for Wistar rats given Torbangun leaf extract orally at a dose of 100 mg/kg BW for seven days. On day 4, groups P1 and P2 were injected with Cisplatin intraperitoneally at a 7 mg/kg BW. The non-parametric data from the study were statistically tested with the Kruskal Wallis test and the post hoc test in the form of the Mann-Whitney test. The test results from statistical analysis showed that the Torbangun leaf extract could reduce tissue damage by significantly reducing hemorrhage, congestion, and vasculitis in the treatment group","PeriodicalId":432813,"journal":{"name":"Veterinary Biomedical and Clinical Journal","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121588844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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