Sensors and Actuators Reports最新文献_第6页

Applications of electrochemical impedance spectroscopy in disease diagnosis—A review 疾病诊断中的电化学阻抗光谱应用 - 综述

IF 6.5

Sensors and Actuators Reports Pub Date : 2024-06-12 DOI: 10.1016/j.snr.2024.100205

José A. Ribeiro , Pedro A.S. Jorge

{"title":"Applications of electrochemical impedance spectroscopy in disease diagnosis—A review","authors":"José A. Ribeiro , Pedro A.S. Jorge","doi":"10.1016/j.snr.2024.100205","DOIUrl":"10.1016/j.snr.2024.100205","url":null,"abstract":"<div><p>Electrochemical impedance spectroscopy (EIS) is a reliable technique for gathering information about electrochemical process occurring at the electrode surface and investigating properties of materials. Furthermore, EIS technique can be a very versatile and valuable tool in analytical assays for detection and quantification of several chemically and biologically relevant (bio)molecules. The first part of this Review (<em>Introduction</em>) provides brief insights into (i) theoretical aspects of EIS, (ii) the instrumentation required to perform the EIS studies and (iii) the most relevant representations of impedance experimental data (such as Nyquist and Bode plots). In the end of this section, (iv) theoretical aspects regarding the fitting of the Randles circuit to experimental data are addressed, not only to obtain information about electrochemical processes but also to illustrate its utility for analytical purposes. The second part of the Review (<em>Impedimetric Detection of Disease Biomarkers</em>) focuses on the applications of EIS in the biomedical field, particularly as analytical technique in electrochemical sensors and biosensors for screening disease biomarkers. In the last section (<em>Conclusions and Perspectives</em>), we discuss main achievements of EIS technique in analytical assays and provide some perspectives, challenges and future applications in the biomedical field.</p></div>","PeriodicalId":426,"journal":{"name":"Sensors and Actuators Reports","volume":"8 ","pages":"Article 100205"},"PeriodicalIF":6.5,"publicationDate":"2024-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666053924000213/pdfft?md5=f068273f787566f7142495848e036e2e&pid=1-s2.0-S2666053924000213-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141401091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ultrasensitive detection of interleukin-6 enabled by three-dimensional spatial amplification 利用三维空间放大技术实现白细胞介素-6 的超灵敏检测

IF 5.9

Sensors and Actuators Reports Pub Date : 2024-06-10 DOI: 10.1016/j.snr.2024.100213

Masaki Yamaguchi , Vivek Shetty

{"title":"Ultrasensitive detection of interleukin-6 enabled by three-dimensional spatial amplification","authors":"Masaki Yamaguchi , Vivek Shetty","doi":"10.1016/j.snr.2024.100213","DOIUrl":"https://doi.org/10.1016/j.snr.2024.100213","url":null,"abstract":"<div><p>Accurately measuring interleukin-6 (IL-6) levels is crucial in both clinical medicine and research due to its role in various physiological and pathological processes. We present proof-of-concept of a novel three-dimensional (3D) spatial amplification method for developing highly sensitive and miniaturized IL-6 biosensors. We designed an IL-6 immunosensor platform utilizing a unique 3D microfluidic structure fabricated with femtosecond-pulsed laser processing. This design features a porous transducer element with over 4500 microcavities, thereby increasing the reaction area by 13-fold compared to traditional 2D designs while maintaining transparency. By combining this 3D structure with a competitive antigen-antibody reaction, the sensor achieved an exceptional limit of detection of 0.27 pg/mL for IL-6 in human blood samples. Additionally, we demonstrated effective control of liquid flow within the porous element using a reduction of pressure and centrifugation speeds. This 3D spatial amplification method offers a promising approach for developing highly sensitive and compact IL-6 biosensors. Such miniaturized sensors hold potential for point-of-care testing devices, enabling convenient and timely IL-6 analysis.</p></div>","PeriodicalId":426,"journal":{"name":"Sensors and Actuators Reports","volume":"8 ","pages":"Article 100213"},"PeriodicalIF":5.9,"publicationDate":"2024-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666053924000298/pdfft?md5=6276c30b19805284de285d9877568356&pid=1-s2.0-S2666053924000298-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141323998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Paper-based immunosensor integrated with bioinspired Cu-polydopamine nanozyme for voltammetric detection of CA-15-3 tumor marker 集成了生物启发铜-多巴胺纳米酶的纸基免疫传感器，用于伏安法检测 CA-15-3 肿瘤标志物

IF 5.9

Sensors and Actuators Reports Pub Date : 2024-06-10 DOI: 10.1016/j.snr.2024.100209

Mohammad Ali Farzin, Seyed Morteza Naghib

{"title":"Paper-based immunosensor integrated with bioinspired Cu-polydopamine nanozyme for voltammetric detection of CA-15-3 tumor marker","authors":"Mohammad Ali Farzin, Seyed Morteza Naghib","doi":"10.1016/j.snr.2024.100209","DOIUrl":"https://doi.org/10.1016/j.snr.2024.100209","url":null,"abstract":"<div><p>This manuscript describes the fabrication and characterization of a highly conductive paper-based nanoplatform for immobliztion of anti-CA 15-3 antibodies. For this purpose, cellulosic filter paper (FP) was first coated with Cu nanosponges (CuNSs) through ion beam sputtering deposition (IBSD) method and then covered with Cu-doped polydopamine nanospheres (Cu-PDA). Polydopamine doped with copper exhibited laccase (multi-copper oxidase)-mimicking properties. Bioinspired by the structure of the active site and the electron transfer mechanism of laccase, Cu-PDA nanozyme catalyzed the oxidation of hydroquinone (HQ) signal probe. In this design, CA-15-3, a prognostic biomarker in the breast cancer, was chosen as a model target. To the best of our knowledge, this is the only paper on the design of an electrochemical biosensor based on dense and uniform CuNSs produced by IBSD. More importantly, Cu-PDA is biocompatible and biodegradable, which makes it a potential competitor in the point-of-care (POC) biosensing applications. Thus, this paper-based sensing strategy can be used in designing cost-effective flexible chips consisting of electrodes printed on paper for in-situ and real-time monitoring biomarkers under clinical conditions. In addition to these outstanding features, the LOD (1.3 mU mL 1) and LOQ (4.3 mU mL 1) of the Ab/HQ/Cu-PDA/CuNSs/FP-based immunosensor was significantly lower than the clinically relevant cut-off level (30 U mL 1). In the practical applications, one of the key superiorities of this immuosensor is the wide DLR (5 mU mL 1–280 U mL 1) which covers the ultimate value of healthy and patient individuals.</p></div>","PeriodicalId":426,"journal":{"name":"Sensors and Actuators Reports","volume":"8 ","pages":"Article 100209"},"PeriodicalIF":5.9,"publicationDate":"2024-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666053924000250/pdfft?md5=04eb6669534ae720eaeb2e18fb583fa8&pid=1-s2.0-S2666053924000250-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141323999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fabrication of humidity monitoring sensor using porous silicon nitride structures for alkaline conditions 利用多孔氮化硅结构制造碱性条件下的湿度监测传感器

IF 5.9

Sensors and Actuators Reports Pub Date : 2024-06-06 DOI: 10.1016/j.snr.2024.100203

Soobin Park , Inseong Hwang , Jae Chan Park , Tae Joo Park , Han-Seung Lee , Sang Yeon Lee , Hyun-Min Yang , Bongyoung Yoo

{"title":"Fabrication of humidity monitoring sensor using porous silicon nitride structures for alkaline conditions","authors":"Soobin Park , Inseong Hwang , Jae Chan Park , Tae Joo Park , Han-Seung Lee , Sang Yeon Lee , Hyun-Min Yang , Bongyoung Yoo","doi":"10.1016/j.snr.2024.100203","DOIUrl":"https://doi.org/10.1016/j.snr.2024.100203","url":null,"abstract":"<div><p>Porous silicon nitride structures were fabricated for a humidity sensor. The porous silicon structures were fabricated by the metal-assisted chemical etching process, and the conformal silicon nitride thin film was deposited by the atomic layer deposition process. The optimized porous sensor with the 10 nm-thick silicon nitride thin film had a hydrophilic surface and compared to other sensors, had an excellent humidity sensing response. Especially, it showed a superior humidity sensing response at 1 kHz with fast response and recovery times of 13.3 s and 12.4 s, respectively, were observed. Based on the electrochemical impedance spectroscopy results, the equivalent circuits and humidity sensing mechanism were discussed. The chemical stability of the silicon nitride was characterized using Tafel analysis in alkaline electrolytes. Additionally, the sensor's humidity sensing capabilities were tested under cement-embedded conditions.</p></div>","PeriodicalId":426,"journal":{"name":"Sensors and Actuators Reports","volume":"8 ","pages":"Article 100203"},"PeriodicalIF":5.9,"publicationDate":"2024-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666053924000195/pdfft?md5=3678eef3e7c87eccb19ae1a05ae621ac&pid=1-s2.0-S2666053924000195-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141308143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sensitivity-enhanced humidity sensor based on a surface core fiber decorated with graphene oxide 基于氧化石墨烯装饰的表芯纤维的灵敏度增强型湿度传感器

IF 5.9

Sensors and Actuators Reports Pub Date : 2024-06-02 DOI: 10.1016/j.snr.2024.100207

Rang Chu , Yanzhen Tan , Fei Zhou , Ye Liu

引用次数: 0

Peptide-based electrochemical detection of prostate cancer-derived exosomes using a dual signal amplification strategy 利用双重信号放大策略对前列腺癌外泌体进行基于肽的电化学检测

IF 5.9

Sensors and Actuators Reports Pub Date : 2024-06-01 DOI: 10.1016/j.snr.2024.100202

Jinlong Li , Wenting Cheng , Chuang Wang , Yuanyuan Miao , Yongfeng Yang

{"title":"Peptide-based electrochemical detection of prostate cancer-derived exosomes using a dual signal amplification strategy","authors":"Jinlong Li , Wenting Cheng , Chuang Wang , Yuanyuan Miao , Yongfeng Yang","doi":"10.1016/j.snr.2024.100202","DOIUrl":"https://doi.org/10.1016/j.snr.2024.100202","url":null,"abstract":"<div><p>Prostate cancer-derived exosomes have important potential as biomarkers for diagnosis and treatment of prostate cancer. But such specific exosomes towards clinical application remains problematic due to their comparatively low concentration in relation to other constituents of blood. Additionally, the presence of particles in blood that share a similar size with exosomes adds to the complexity of their selective and sensitive detection. Consequently, the detection of exosomes derived from prostate cancer in intricate biological settings necessitates the implementation of highly sensitive and specific biosensors. Herein, we report an electrochemical biosensor for prostate cancer-derived exosomes detection, with two-level selectivity achieved through a sandwich structure involving specific peptides and two-level amplification utilizing the combination of biotin-streptavidin linkage and G-quadruplex hemin mimetic peroxidase to enhance the sensitivity. Evaluation of PSMA positive exosomes at various concentrations demonstrates a remarkable limit of detection as low as 26 particles/μL, as well as an excellent linear sensor response spanning from 1.0 × 10<sup>2</sup> to 1.0 × 10<sup>7</sup> particles/μL. Compared to the enzymatic biosensor, this biosensor proves more versatile without a label or enzyme, and may be more promising for clinical applications.</p></div>","PeriodicalId":426,"journal":{"name":"Sensors and Actuators Reports","volume":"7 ","pages":"Article 100202"},"PeriodicalIF":5.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666053924000183/pdfft?md5=2439407a345670f6b65f7aa925675782&pid=1-s2.0-S2666053924000183-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141249408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of an electrochemical biosensor with TiN nano-electrode arrays for IL-6 detection 利用 TiN 纳米电极阵列开发用于检测 IL-6 的电化学生物传感器

IF 5.9

Sensors and Actuators Reports Pub Date : 2024-06-01 DOI: 10.1016/j.snr.2024.100204

Shu-Tsai Cheng , Ching-Fen Shen , Jeng-Huei Shiau , Kuan-Ru Chou , Wei-Yu Lin , Chun-Lung Lien , Chao-Min Cheng

{"title":"Development of an electrochemical biosensor with TiN nano-electrode arrays for IL-6 detection","authors":"Shu-Tsai Cheng , Ching-Fen Shen , Jeng-Huei Shiau , Kuan-Ru Chou , Wei-Yu Lin , Chun-Lung Lien , Chao-Min Cheng","doi":"10.1016/j.snr.2024.100204","DOIUrl":"10.1016/j.snr.2024.100204","url":null,"abstract":"<div><p>In this study, we developed a novel electrochemical biosensor for detecting IL-6 that uses a nano-electrode array (NEA) fabricated via standard CMOS processing. Miniaturizing the electrodes to the nanoscale and arranging them in an array to form an NEA facilitated the creation of a higher electric field magnitude, compared to that available via the use of microelectrodes, that could be used to improve biosensor sensitivity. Additionally, the array configuration of the NEA aided in providing sufficient reaction sites. Each nano-electrode in the NEA was cylindrically shaped, with a radius of 0.1 µm, and a top layer formed by TiN physical vapor deposition. Each NEA biosensor was divided into four independent banks, with each bank including a set of WE, CE and RE. These banks were capable of independently inputting and outputting electrical signals. This design allowed the NEA biosensor to undergo selective modification by CV input. In this study, we discuss and address material and contamination issues associated with CMOS-produced NEAs and their uses as biosensors. To ameliorate these issues, we stored materials and products in a nitrogen-controlled cabinet and conducted pretreatment cleaning on the electrodes. Both steps had a noticeable impact on the cleanliness of the electrode surfaces. These optimized conditions resulted in a remarkable 96.6 % reduction in R<sub>ct</sub>. The NEA surface was functionalized by electrochemically grafting diazonium salts subsequently immobilized with anti-IL-6 antibodies via EDC/NHS chemistry. The resulting NEA biosensor demonstrated sufficient sensitivity to rapidly distinguish inflammatory conditions and disease severity. This showcases the potential for using NEA devices mass-produced via standard CMOS processing as electrodes for biosensors.</p></div>","PeriodicalId":426,"journal":{"name":"Sensors and Actuators Reports","volume":"8 ","pages":"Article 100204"},"PeriodicalIF":5.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666053924000201/pdfft?md5=a148fc71168933c01717ae24ad21f182&pid=1-s2.0-S2666053924000201-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141276490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hypersensitive detection of CYFRA21-1 by SERS dual antibody sandwich method 用 SERS 双抗体夹心法超灵敏检测 CYFRA21-1

IF 5.9

Sensors and Actuators Reports Pub Date : 2024-05-22 DOI: 10.1016/j.snr.2024.100198

Song Ge , Mingxin Wang , Shunhua Zhu , Han Wu , Jing Li , Dongsheng Liu , Qingli Huang , Shibao Li , Xiaojing Sun

{"title":"Hypersensitive detection of CYFRA21-1 by SERS dual antibody sandwich method","authors":"Song Ge , Mingxin Wang , Shunhua Zhu , Han Wu , Jing Li , Dongsheng Liu , Qingli Huang , Shibao Li , Xiaojing Sun","doi":"10.1016/j.snr.2024.100198","DOIUrl":"https://doi.org/10.1016/j.snr.2024.100198","url":null,"abstract":"<div><h3>Purpose</h3><p>As an important reference index for the early diagnosis of non-small cell lung cancer (NSCLC), CYFRA21-1 still lacks the detection of low equipment cost, wide linear range and high sensitivity. Surface-enhanced Raman scattering (SERS) is a vibration spectrum technology based on the surface plasma of precious metal nanoparticles, which has been effectively applied to the detection of tumor markers. The combination of SERS technology and sensors has great potential in the ultrasensitive detection of tumor markers. The purpose of this study was to develop a sensitive method using SERS to quantitatively detect CYFRA21-1 for early diagnosis of NSCLC.</p></div><div><h3>Methods</h3><p>A double-antibody sandwich immunoassay based on SERS was designed and tested to implement the ultrasensitive detection of CYFRA21-1 in the serum of NSCLC patients.</p></div><div><h3>Results</h3><p>Gold @Ag nanorods (Au @Ag NRs) with higher Raman signals were prepared and used as probes, while magnetic graphene oxide was used as a magnetic substrate. The immunized probe, immune substrate and CYFRA21-1 standard substance in the buffer system formed a double-antibody sandwich structure. The standard curve displayed a liner range from 1pg mL<sup>−1</sup> to 10 ng mL<sup>−1</sup>, and the detection limit (LOD) is 0.8943pg mL<sup>−1</sup>. The Raman intensity exhibited a wide linear relationship with the logarithm of CYFRA21-1 concentration.</p></div><div><h3>Conclusion</h3><p>Our study successfully established a double-antibody sandwich immunoassay based on SERS. This method demonstrated high specificity and sensitivity for detecting CYFRA21-1 protein content in serum. It has the potential to be applied for early detection of lung cancer biomarkers.</p></div>","PeriodicalId":426,"journal":{"name":"Sensors and Actuators Reports","volume":"7 ","pages":"Article 100198"},"PeriodicalIF":5.9,"publicationDate":"2024-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666053924000146/pdfft?md5=04c4276bb4840e5ba02b5e803153af33&pid=1-s2.0-S2666053924000146-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141083960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fluorescence based dopamine detection 基于荧光的多巴胺检测

IF 5.9

Sensors and Actuators Reports Pub Date : 2024-05-18 DOI: 10.1016/j.snr.2024.100199

Valeriia Sliesarenko , Urban Bren , Aleksandra Lobnik

{"title":"Fluorescence based dopamine detection","authors":"Valeriia Sliesarenko , Urban Bren , Aleksandra Lobnik","doi":"10.1016/j.snr.2024.100199","DOIUrl":"https://doi.org/10.1016/j.snr.2024.100199","url":null,"abstract":"<div><p>Dopamine is an important hormone and neurotransmitter, and its levels in human fluids can indicate stress, depression, and various mental disorders. Food products, as well as medications, affect its level in the human body greatly. Therefore, dopamine monitoring is crucial, and necessary for improving the quality of life. The priority is to search for simple and environmentally friendly sensor systems for the in vitro detection of dopamine, enabling mass utilization.</p><p>In this study, we explored the use of o-phthalaldehyde (OPA) as an indicator for the detection of dopamine, with fluorescence in the visible range (λ<sub>ex</sub>/λ<sub>em</sub> = 390/455 nm), while direct dopamine fluorescence measurement was in the UV range (λ<sub>ex</sub>/λ<sub>em</sub> = 280/320 nm). The longer excitation/emission wavelengths of dopamine-OPA complex, as well as lower detection limits, are useful for developing a simple detection method using LEDs. Three types of poloxamers were tested as additives to improve the fluorescence signal from the reaction between dopamine and OPA. Pluronic F127 led to a 16-fold increase in the fluorescence. Utilizing 4% Pluronic F127 with OPA at pH 7 resulted in a linear response within concentration ranges of dopamine (0.5–3 µM), achieving a limit of detection of 0.015 µM. In contrast, a direct detection of dopamine within the same range exhibited a detection limit of 0.13 µM.</p></div>","PeriodicalId":426,"journal":{"name":"Sensors and Actuators Reports","volume":"7 ","pages":"Article 100199"},"PeriodicalIF":5.9,"publicationDate":"2024-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666053924000158/pdfft?md5=1f2429dcc48f90f8a9afc65d0ad28fe7&pid=1-s2.0-S2666053924000158-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141089973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Review: Perovskite nanostructures materials versatile platform for advance biosensor applications 回顾：用于先进生物传感器应用的透镜纳米结构材料多功能平台

IF 5.9

Sensors and Actuators Reports Pub Date : 2024-05-17 DOI: 10.1016/j.snr.2024.100201

Vivek B. Korde , Suhas Khot , Dinkar B. Kamble , Shankar Amalraj

{"title":"Review: Perovskite nanostructures materials versatile platform for advance biosensor applications","authors":"Vivek B. Korde , Suhas Khot , Dinkar B. Kamble , Shankar Amalraj","doi":"10.1016/j.snr.2024.100201","DOIUrl":"https://doi.org/10.1016/j.snr.2024.100201","url":null,"abstract":"<div><p>The distinct presence of a central atom surrounded by eight ligands leads to higher light absorption and charge carrier mobility in perovskite materials. The peculiar nature of the structure inspires all the scientists and researchers to work more in sustainable applications, such as solar cells, light emitting diodes, transistor and biosensors. The capability of perovskite material in detecting smaller molecules such as O<sub>2</sub>, NO<sub>2</sub> and CO<sub>2</sub> is higher. Therefore, several biosensors are demonstrated based on the perovskite nanomaterial to various chemical and biological species with both solid and solution states. The immense sources of research articles thrived the author, to review the perovskite nanomaterials in the dimension of biosensor application extensively. This review covers major three areas of perovskite nanomaterial, such as components and characteristics of biosensors, properties and preparation of perovskite materials and application and research trends of perovskite nanostructure biosensor.</p></div>","PeriodicalId":426,"journal":{"name":"Sensors and Actuators Reports","volume":"7 ","pages":"Article 100201"},"PeriodicalIF":5.9,"publicationDate":"2024-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666053924000171/pdfft?md5=2c0c5fbdf52e1a12e7eecbbc9327d3bc&pid=1-s2.0-S2666053924000171-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141067298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0