Sensors and Actuators Reports最新文献_第7页

Fast and sensitive virus detection using a plasmonic sensor that integrates electrokinetically assisted sampling and surface-enhanced Raman scattering 使用集成了电动辅助采样和表面增强拉曼散射的等离子体传感器进行快速灵敏的病毒检测

IF 6.5

Sensors and Actuators Reports Pub Date : 2024-12-26 DOI: 10.1016/j.snr.2024.100273

Shamim Azimi , Maryam Moridsadat , Bhavin Shastri , Bruce W. Banfield , Carlos Escobedo , Aristides Docoslis

{"title":"Fast and sensitive virus detection using a plasmonic sensor that integrates electrokinetically assisted sampling and surface-enhanced Raman scattering","authors":"Shamim Azimi , Maryam Moridsadat , Bhavin Shastri , Bruce W. Banfield , Carlos Escobedo , Aristides Docoslis","doi":"10.1016/j.snr.2024.100273","DOIUrl":"10.1016/j.snr.2024.100273","url":null,"abstract":"<div><div>We present a novel plasmonic biosensing method for on-chip detection on viral particles featuring a microelectrode platform that integrates accelerated sampling of virus with surface-enhanced Raman scattering (SERS). We show experimentally that our approach can produce spectacular results owing to the unique incorporation of two key features: (1) Concentration amplification of virus on the SERS-active substrate; (2) Local plasmonic activity enhancement due to the targeted superimposition of silver nanoparticles on the captured virus sites. When tested for the detection of the M13 bacteriophage our “sandwich” assay yielded excellent reproducibility (signal variation <6 %) and a very low limit of detection (1.13 × 10<sup>2</sup> pfu/ml). Compared with the performance of our standard SERS substrates, SERS signals stronger by at least one order of magnitude are typically achieved. In addition to experimental results, our work also includes finite element (COMSOL Multiphysics) and finite-difference time-domain (FDTD) simulations that provide insights into the mechanisms of concentration amplification and plasmonic activity enhancement, respectively.</div></div>","PeriodicalId":426,"journal":{"name":"Sensors and Actuators Reports","volume":"9 ","pages":"Article 100273"},"PeriodicalIF":6.5,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143158247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Platinum nanoparticles decorated on electrodeposited Ti3C2Tx MXene nanosheets as an ultrasensitive biosensor for CA15–3 detection 电沉积Ti3C2Tx MXene纳米片上修饰的铂纳米粒子作为CA15-3检测的超灵敏生物传感器

IF 6.5

Sensors and Actuators Reports Pub Date : 2024-12-26 DOI: 10.1016/j.snr.2024.100278

Sepideh Shafaei , Rahim Mohammad-Rezaei , Balal Khalilzadeh , Ibrahim Isildak

{"title":"Platinum nanoparticles decorated on electrodeposited Ti3C2Tx MXene nanosheets as an ultrasensitive biosensor for CA15–3 detection","authors":"Sepideh Shafaei , Rahim Mohammad-Rezaei , Balal Khalilzadeh , Ibrahim Isildak","doi":"10.1016/j.snr.2024.100278","DOIUrl":"10.1016/j.snr.2024.100278","url":null,"abstract":"<div><div>In this study, an efficient and ultrasensitive biosensor based on platinum nanoparticles decorated on MXene nanosheets (NSs) was reported for the detection of CA15–3 breast cancer biomarker. In order to increase the accuracy and reproducibility of the fabricated biosensor, MXene NSs and platinum nanoparticles (PtNPs) were electrochemically deposited on the surface of glassy carbon electrode (MXene-Pt/GCE). The synergistic effect of MXene and PtNPs caused an increased conductivity, fast electron transfers, amplified sensitivity and improved stabilization of streptavidin and CA15–3 antibody on the electrode surface. According to the electrochemical results, the electroactive surface area of MXene-Pt/GCE was obtained 0.1345 cm<sup>2</sup> which was remarkably more than GCE. The detection limit and linear range for the developed CA15–3 breast cancer biosensor were 1 nU and 1 to 100 nU, respectively. Based on the data, the proposed biosensor exhibited unique reproducibility, stability, and selectivity which can be differentiate between the healthy serum samples and patients suffering from breast cancer.</div></div>","PeriodicalId":426,"journal":{"name":"Sensors and Actuators Reports","volume":"9 ","pages":"Article 100278"},"PeriodicalIF":6.5,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143158253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cortisol detection using a Long Period Fiber Grating Immunosensor coated with Graphene Oxide 用氧化石墨烯涂层的长周期光纤光栅免疫传感器检测皮质醇

IF 6.5

Sensors and Actuators Reports Pub Date : 2024-12-25 DOI: 10.1016/j.snr.2024.100279

Simone Soares , Ambra Giannetti , Flavio Esposito , Lucia Sansone , Anubhav Srivastava , Stefania Campopiano , Michele Giordano , Margarida Facão , Nuno F. Santos , Agostino Iadicicco , Carlos Marques , Francesco Chiavaioli

{"title":"Cortisol detection using a Long Period Fiber Grating Immunosensor coated with Graphene Oxide","authors":"Simone Soares , Ambra Giannetti , Flavio Esposito , Lucia Sansone , Anubhav Srivastava , Stefania Campopiano , Michele Giordano , Margarida Facão , Nuno F. Santos , Agostino Iadicicco , Carlos Marques , Francesco Chiavaioli","doi":"10.1016/j.snr.2024.100279","DOIUrl":"10.1016/j.snr.2024.100279","url":null,"abstract":"<div><div>Recirculating Aquaculture Systems (RAS) have revolutionized the protein production sector in aquaculture, leading to significant growth and expansion of the industry. Despite the success of RAS in aquaculture, there are challenges related to stress in fish raised in these systems, which can impact their food intake, growth, and overall well-being. One of the major limitations in the aquaculture industry is the lack of smart sensors for real-time detection of stress hormones like cortisol, hindering our ability to understand and effectively manage the welfare of fish in these systems. In this work, a graphene oxide (GO) coated long period grating (LPG) was fabricated into a double-clad optical fiber (DCF) with W-shaped refractive index profile. The working point of the device was tuned to the mode transition region to enhance its sensitivity against outer medium changes. It was further integrated into a microfluidic system and the fiber surface was functionalized with specific anti-cortisol antibodies for the detection of cortisol. Finally, the performance of this immunosensor was evaluated for a cortisol concentration range of 0.01 ng/mL to 100 ng/mL, a wide working range of concentrations of relevant interest, achieving a limit of detection (LOD) of 0.06 ng/mL. Moreover, a selectivity test using testosterone and glucose as interfering substances was carried out.</div></div>","PeriodicalId":426,"journal":{"name":"Sensors and Actuators Reports","volume":"9 ","pages":"Article 100279"},"PeriodicalIF":6.5,"publicationDate":"2024-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143158250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Laser-induced graphene electrochemical immunosensors for rapid and sensitive serological detection: A case study on dengue detection platform 用于快速灵敏血清学检测的激光诱导石墨烯电化学免疫传感器：登革热检测平台的案例研究

IF 6.5

Sensors and Actuators Reports Pub Date : 2024-12-24 DOI: 10.1016/j.snr.2024.100276

Supawee Inlumphan , Winadda Wongwiriyapan , Narathon Khemasiri , Prapakorn Rattanawarinchai , Piyawan Leepheng , Panuwat Luengrojanakul , Tuksadon Wuttikhun , Michiko Obata , Masatsugu Fujishige , Kenji Takeuchi , Mayuree Phonyiem Reilly , Teerayut Uwanno , Mati Horprathum , Supanit Porntheeraphat , Kannika Sitthisuwannakul , Supranee Phanthanawiboon , Annop Klamchuen

{"title":"Laser-induced graphene electrochemical immunosensors for rapid and sensitive serological detection: A case study on dengue detection platform","authors":"Supawee Inlumphan , Winadda Wongwiriyapan , Narathon Khemasiri , Prapakorn Rattanawarinchai , Piyawan Leepheng , Panuwat Luengrojanakul , Tuksadon Wuttikhun , Michiko Obata , Masatsugu Fujishige , Kenji Takeuchi , Mayuree Phonyiem Reilly , Teerayut Uwanno , Mati Horprathum , Supanit Porntheeraphat , Kannika Sitthisuwannakul , Supranee Phanthanawiboon , Annop Klamchuen","doi":"10.1016/j.snr.2024.100276","DOIUrl":"10.1016/j.snr.2024.100276","url":null,"abstract":"<div><div>Here, we present a diagnostic on a chip platform based on laser-induced graphene (LIG) electrochemical immunosensors for serological detection. The electrochemical immunosensors are fabricated through CO<sub>2</sub> laser induction on polyimide (PI) sheets. Optimal electrochemical activity of LIG electrodes is obtained under optimized conditions of laser fluence. To verify the application, the serological detection platform was demonstrated. After functionalization with dengue virus (DENV) antigen, the LIG electrochemical immunosensors are able to sense the presence of mouse anti-flavivirus monoclonal (4G2) antibody in a wide linear working range of 25–20,000 ng/ml with the limit of detection (LOD) of 17.41 ng/ml. A specific recognition with 4G2 antibodies against with media protein and isotype is confirmed. Furthermore, the reliability of LIG electrochemical immunosensors compared to conventional enzyme-linked immunosorbent assay (ELISA) is verified through the NS1 antibodies identification in human blood serum clinical samples at room temperature. Our results highlight that the LIG-based electrode is a promising platform for electrochemical immunosensors, aimed at developing reliable and practical diagnostic tools for serological detection. These tools enable early diagnosis of infectious diseases, as well as non-invasive and rapid screening.</div></div>","PeriodicalId":426,"journal":{"name":"Sensors and Actuators Reports","volume":"9 ","pages":"Article 100276"},"PeriodicalIF":6.5,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143157708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Microfluidic device for both active and passive cell separation techniques: A review 微流控装置用于主动和被动细胞分离技术的研究进展

IF 6.5

Sensors and Actuators Reports Pub Date : 2024-12-20 DOI: 10.1016/j.snr.2024.100277

Muhammad Asraf Mansor , Muhammad Asyraf Jamrus , Chong Kar Lok , Mohd Ridzuan Ahmad , Michal Petrů , Seyed Saeid Rahimian Koloor

{"title":"Microfluidic device for both active and passive cell separation techniques: A review","authors":"Muhammad Asraf Mansor , Muhammad Asyraf Jamrus , Chong Kar Lok , Mohd Ridzuan Ahmad , Michal Petrů , Seyed Saeid Rahimian Koloor","doi":"10.1016/j.snr.2024.100277","DOIUrl":"10.1016/j.snr.2024.100277","url":null,"abstract":"<div><div>Microfluidic separation of particles and cells has been extensively developed in recent years in a wide range of applications of sciences, engineering, and industry. At the same time, this area has been explored within the framework of interdisciplinary study, resulting in several experiments conducted in this field. Due to the heterogeneity of cells, label-free methods that utilize the inherent physical properties of cells to separate, offer more advantages including high throughput, simple design, reduced sample volumes, and low device cost. This paper comprehensively studies the latest progress in microfluidic technology for both active and passive cell separation techniques. In order to limit the extent of this work, our primary emphasis is on six common methods of cell separation: acoustophoresis, dielectrophoresis, magnetophoresis, inertial, pinched flow fractionation (PFF), and deterministic lateral displacement (DLD). We elaborate on the efficiency, throughput rate, and clogging in microfluidic devices. In addition, the advantages and limitations of both microfluidics devices were discussed.</div></div>","PeriodicalId":426,"journal":{"name":"Sensors and Actuators Reports","volume":"9 ","pages":"Article 100277"},"PeriodicalIF":6.5,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143157707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advances in neural information detection sensors for spatial cognition research: A review 空间认知神经信息检测传感器研究进展

IF 6.5

Sensors and Actuators Reports Pub Date : 2024-12-17 DOI: 10.1016/j.snr.2024.100274

Mingchuan Wang , Shiya Lv , Yu Wang , Zhaojie Xu , Peiyao Jiao , Yu Liu , Siyu Zhang , Yirong Wu , Mixia Wang , Jinping Luo , Shi Yan , Zhimei Qi , Yilin Song , Juntao Liu , Xinxia Cai

{"title":"Advances in neural information detection sensors for spatial cognition research: A review","authors":"Mingchuan Wang , Shiya Lv , Yu Wang , Zhaojie Xu , Peiyao Jiao , Yu Liu , Siyu Zhang , Yirong Wu , Mixia Wang , Jinping Luo , Shi Yan , Zhimei Qi , Yilin Song , Juntao Liu , Xinxia Cai","doi":"10.1016/j.snr.2024.100274","DOIUrl":"10.1016/j.snr.2024.100274","url":null,"abstract":"<div><div>Spatial cognition is crucial for animal survival and reflects higher-order cognitive processes achieved through the coordination of neurons, local networks, and the brain's overall structure. Neural biosensors reliably detect signals in the brain at multiple levels, including neuronal action potentials (spikes), local field potentials (LFP), and blood-oxygen-level-dependent (BOLD) signals, which are interconnected yet distinct. These signals have significantly contributed to spatial cognition research. However, a comprehensive analysis across these levels is lacking, limiting full understanding of neural encoding and decoding mechanisms. This review introduces biosensor methods for detecting neural signals at various levels and discusses their applications in spatial cognition. It aims to inspire future research by promoting multi-modal, multi-level approaches for comprehensive decoding of neural mechanisms.</div></div>","PeriodicalId":426,"journal":{"name":"Sensors and Actuators Reports","volume":"9 ","pages":"Article 100274"},"PeriodicalIF":6.5,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143157706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Electrospinning ZnS:Ni quantum dots into carbon nanofibrous structure as a base for the electrochemical aptasensor for detection of trypsin 静电纺丝ZnS:Ni量子点成碳纳米纤维结构，作为检测胰蛋白酶的电化学感应传感器的基础

IF 6.5

Sensors and Actuators Reports Pub Date : 2024-12-15 DOI: 10.1016/j.snr.2024.100272

Haniyeh Shantiaei, Mahmoud Roushani, Farzaneh Mohammadi

{"title":"Electrospinning ZnS:Ni quantum dots into carbon nanofibrous structure as a base for the electrochemical aptasensor for detection of trypsin","authors":"Haniyeh Shantiaei, Mahmoud Roushani, Farzaneh Mohammadi","doi":"10.1016/j.snr.2024.100272","DOIUrl":"10.1016/j.snr.2024.100272","url":null,"abstract":"<div><div>Herein, ZnS:Ni quantum dots embedded within carbon nanofibers (ZnS:Ni/CNFs) are synthesized via a simple electrospinning technology with a subsequent carbonization process and proposed for biosensing purposes. This hybrid material was applied as a substrate for aptamer immobilization aiming at Trypsin sensing. It is revealed that the electrochemical Trypsin aptasensor developed based on the novel ZnS:Ni/CNFs composite exhibited superior analysis performance to previously reported Trypsin aptasensor, such as a wide linear range from 0.1 fg mL<sup>−1</sup> to 600 ng mL<sup>−1</sup> and low detection limit of 0.03 fg mL<sup>−1</sup> (S/<em>N</em> = 3), excellent reproducibility and selectivity. In addition, apt/ ZnS:Ni CNFs/GCE can detect Trypsin present in human serum samples. This work can inspire researchers to build functional hybrid nanomaterials based on nanofibers for the purpose of generating electrochemical biosensors. Additionally, the implementation of the suggested platform has the potential to be highly beneficial in future studies and extends their applications in biosensors and health monitoring.</div></div>","PeriodicalId":426,"journal":{"name":"Sensors and Actuators Reports","volume":"9 ","pages":"Article 100272"},"PeriodicalIF":6.5,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143157709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Senescence-associated β-galactosidase detection in human oral cancer samples using bimetallic (Fe, Cu)-MOF-919 impedimetric immunosensor 用双金属(Fe, Cu)-MOF-919阻抗免疫传感器检测人口腔癌样品中衰老相关β-半乳糖苷酶

IF 6.5

Sensors and Actuators Reports Pub Date : 2024-12-14 DOI: 10.1016/j.snr.2024.100271

Priya Vijayaraghavan , Sathyadevi Palanisamy , Yen-Yun Wang , Pamela Berilyn So , Chia-Her Lin , Shey-Cherng Tzou , Shyng-Shiou F. Yuan , Yun-Ming Wang

{"title":"Senescence-associated β-galactosidase detection in human oral cancer samples using bimetallic (Fe, Cu)-MOF-919 impedimetric immunosensor","authors":"Priya Vijayaraghavan , Sathyadevi Palanisamy , Yen-Yun Wang , Pamela Berilyn So , Chia-Her Lin , Shey-Cherng Tzou , Shyng-Shiou F. Yuan , Yun-Ming Wang","doi":"10.1016/j.snr.2024.100271","DOIUrl":"10.1016/j.snr.2024.100271","url":null,"abstract":"<div><div>Clinical diagnosis of diseases like cancer, requires rapid and ultrasensitive screening methods. β-galactosidase (β-gal) is a glycoside hydrolase enzyme, that is upregulated in senescent cells and primary ovarian cancer cells. It is considered a significant biomarker for cellular senescence and primary ovarian cancers. The current study demonstrates the designing of a bimetallic metal-organic framework, (Fe, Cu)-MOF-919, as an ultrasensitive electrochemical immunosensor for investigating ꞵ-galactosidase (β-gal) enzyme on screen-printed carbon electrodes (SPCE) using electrochemical impedance spectroscopy (EIS) in human oral cancer plasma samples. The sensor exhibited a linear response in a wide concentration of β-gal ranging from 10 fg/mL to 1 ng/mL with a limit of detection (LOD) of 4.79 fg/mL and a limit of quantification (LOQ) of 14.53 fg/mL. Furthermore, the sensor confirmed outstanding selectivity and sensitivity against biologically significant interfering molecules. Analyses of β-gal in human oral cancer samples also demonstrated the potential of β-gal for clinical diagnosis. The sensing approach holds substantial clinical relevance by being a promising option for designing latent biosensors.</div></div>","PeriodicalId":426,"journal":{"name":"Sensors and Actuators Reports","volume":"9 ","pages":"Article 100271"},"PeriodicalIF":6.5,"publicationDate":"2024-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143157705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Flap endonuclease 1 (FEN1) biomarker as a new diagnostic target for the biosensing of cancer 皮瓣内切酶1 （FEN1）作为肿瘤生物传感新诊断靶点

IF 6.5

Sensors and Actuators Reports Pub Date : 2024-12-09 DOI: 10.1016/j.snr.2024.100270

Saba Mahboubi , Mehdi Evazalipour , Ehsan Zamani , Nozhat Zebardast , Alireza Farokhrouz , Rahim Nosrati

{"title":"Flap endonuclease 1 (FEN1) biomarker as a new diagnostic target for the biosensing of cancer","authors":"Saba Mahboubi , Mehdi Evazalipour , Ehsan Zamani , Nozhat Zebardast , Alireza Farokhrouz , Rahim Nosrati","doi":"10.1016/j.snr.2024.100270","DOIUrl":"10.1016/j.snr.2024.100270","url":null,"abstract":"<div><div>Flap endonuclease 1 (FEN1) is a structure-specific nuclease that plays a role in DNA replication and genome stability. FEN1 is overexpressed in proliferative cancers and correlates with the grade and aggressiveness of the cancer, suggesting that it could potentially be considered a promising biomarker for various cancer types. Due to the initiation of cancer is related to the lack of the activity of FEN1 nuclease, the detection and quantification of FEN1 is significance for cancer diagnosis in early stage. There are various approaches to detect the different types of cancer biomarkers. In this context, biosensing platforms and nanotechnology-based methods have attracted much attention. To date, the sensitivity and performance of biosensors can enhance by nanomaterials/nanoparticles that have been incorporated in biosensing platforms. This review overview a brief classification and description of the advancement of biosensors and nanobiosensors for the detection and quantitation of FEN1 based on optical and electrochemical platforms.</div></div>","PeriodicalId":426,"journal":{"name":"Sensors and Actuators Reports","volume":"9 ","pages":"Article 100270"},"PeriodicalIF":6.5,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143157704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Direct anodic electrografting of Osmium complexes on Indium tin oxide 锇配合物在氧化铟锡上的直接阳极电接枝

IF 6.5

Sensors and Actuators Reports Pub Date : 2024-12-07 DOI: 10.1016/j.snr.2024.100266

Haeyeon Lee , Su Yong Go , Chae Yun Kim , Eun Joong Kim , Chung Mu Kang , Taek Dong Chung

{"title":"Direct anodic electrografting of Osmium complexes on Indium tin oxide","authors":"Haeyeon Lee , Su Yong Go , Chae Yun Kim , Eun Joong Kim , Chung Mu Kang , Taek Dong Chung","doi":"10.1016/j.snr.2024.100266","DOIUrl":"10.1016/j.snr.2024.100266","url":null,"abstract":"<div><div>Indium tin oxide (ITO) is a widely used electrode material in electrochemical biosensors owing to its beneficial characteristics such as transparency and chemical inertness. The exceptionally sluggish kinetics of heterogeneous electron transfer in ITO provides an exceptionally low background current, making electron mediators essential for electrochemical sensors. However, the chemical modification of ITO with molecular mediators is still challenging. Few straightforward and credible methods are available to obtain sufficiently thin mediator films firmly anchored on the ITO without losing its inherent benefits, including low background current and transparency. This study demonstrated the anodic electrografting of three osmium complexes, which allowed the formation of molecular mediator monolayers on ITO. The densely packed monolayer of osmium complexes retained their reversible redox processes over hundreds of potential cycles. We confirmed electron mediation by the modified electrodes for 4-aminophenol oxidation, suggesting a simple protocol for developing ITO-based biosensors functionalized with molecular mediators.</div></div>","PeriodicalId":426,"journal":{"name":"Sensors and Actuators Reports","volume":"9 ","pages":"Article 100266"},"PeriodicalIF":6.5,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143157701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0